CN118358947A - Medical consumable transfer device and nucleic acid detection all-in-one machine with same - Google Patents
Medical consumable transfer device and nucleic acid detection all-in-one machine with same Download PDFInfo
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- CN118358947A CN118358947A CN202310104423.7A CN202310104423A CN118358947A CN 118358947 A CN118358947 A CN 118358947A CN 202310104423 A CN202310104423 A CN 202310104423A CN 118358947 A CN118358947 A CN 118358947A
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- 238000012546 transfer Methods 0.000 title claims abstract description 112
- 238000001514 detection method Methods 0.000 title claims abstract description 18
- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 10
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 10
- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 10
- 230000007246 mechanism Effects 0.000 claims description 40
- 230000003321 amplification Effects 0.000 claims description 26
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 26
- 239000003153 chemical reaction reagent Substances 0.000 claims description 21
- 238000000605 extraction Methods 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 10
- 239000012491 analyte Substances 0.000 claims description 8
- 230000005540 biological transmission Effects 0.000 claims description 7
- 238000002360 preparation method Methods 0.000 claims description 5
- 238000003556 assay Methods 0.000 claims 2
- 230000000149 penetrating effect Effects 0.000 claims 1
- 238000005259 measurement Methods 0.000 description 8
- 238000012360 testing method Methods 0.000 description 8
- 239000012528 membrane Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000009471 action Effects 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G35/00—Mechanical conveyors not otherwise provided for
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G47/00—Article or material-handling devices associated with conveyors; Methods employing such devices
- B65G47/74—Feeding, transfer, or discharging devices of particular kinds or types
- B65G47/90—Devices for picking-up and depositing articles or materials
- B65G47/902—Devices for picking-up and depositing articles or materials provided with drive systems incorporating rotary and rectilinear movements
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Mechanical Engineering (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The application provides a medical consumable transfer device and a nucleic acid detection integrated machine with the same, wherein the medical consumable transfer device comprises: the first driving piece drives the ferry frame to move along a first horizontal direction, and the second driving piece drives the first bearing table to move relative to the ferry frame along a vertical direction; the third driving piece drives the transfer frame to move along the second horizontal direction; the gripper can move along the vertical direction and the first horizontal direction; the first plummer has first loading position and dodges the position, and when first plummer was located first loading position, the upper surface of first plummer was in same horizontal plane with the upper surface of transferring the frame, and the tongs can remove to the top of first plummer and snatch medical consumable, and when first plummer was located dodges the position, the top of transferring the frame can remove to first plummer, and the tongs can place medical consumable on the transfer frame. According to the technical scheme provided by the application, the problem of complex movement stroke of the gripper in the prior art can be solved.
Description
Technical Field
The invention relates to the technical field of nucleic acid detection, in particular to a medical consumable transfer device and a nucleic acid detection integrated machine with the same.
Background
In clinical medicine testing laboratories, a large number of medical consumables are often required to participate in the testing process for large volume testing requirements.
In the prior art, medical consumables are grabbed through the tongs, and the medical consumables are moved by the aid of movement of the tongs, so that the medical consumables are transported. However, since the working path of the consumable is complicated, the gripper needs to grasp and transfer the consumable from a plurality of positions, so that the movement stroke of the gripper in the prior art is complicated, the movement complexity of the gripper is increased, and the transmission efficiency is reduced.
Disclosure of Invention
The invention provides a medical consumable transfer device and a nucleic acid detection integrated machine with the same, which are used for solving the problem of complex movement stroke of a gripper in the prior art.
According to an aspect of the present invention, there is provided a medical consumable transfer apparatus, comprising: the ferry mechanism comprises a ferry frame, a first driving piece, a second driving piece and a first bearing table, wherein the first driving piece can drive the ferry frame to move along a first horizontal direction, and the second driving piece can drive the first bearing table to move along a vertical direction relative to the ferry frame; the transfer mechanism comprises a transfer frame and a third driving piece, and the third driving piece can drive the transfer frame to move along a second horizontal direction perpendicular to the first horizontal direction; a gripping mechanism including a grip movable in a vertical direction and a first horizontal direction; the first bearing table is provided with a first bearing position and an avoidance position lower than the first bearing position, when the first bearing table is located at the first bearing position, the upper surface of the first bearing table and the upper surface of the transfer frame are located on the same horizontal plane, the gripper can move to the upper portion of the first bearing table and grasp medical consumables, when the first bearing table is located at the avoidance position, the transfer frame can move to the upper portion of the first bearing table, and the gripper can place the medical consumables on the transfer frame.
Further, the ferry frame includes: the first driving piece can drive the frame body to move along a first horizontal direction; the second plummer is arranged on the frame body, the second plummer is provided with an avoidance port, the first plummer can vertically move to penetrate through the avoidance port, the first plummer also is provided with a second bearing position lower than the first bearing position, and when the first plummer is positioned at the second bearing position, the upper surface of the first plummer is not higher than the upper surface of the second plummer.
Further, the ferry mechanism further comprises a driving gear and a driven rack which are meshed, the driving gear is rotatably arranged on the ferry frame, the second driving piece is in driving connection with the driving gear, the driven rack extends vertically, and the driven rack is connected with the first bearing table.
Further, the ferry mechanism further comprises a first guide rail and a first sliding groove, wherein the first guide rail extends along the vertical direction, the first guide rail is arranged on the ferry frame, the first sliding groove is arranged on the first bearing table, and the first sliding groove is movably arranged on the first guide rail along the extending direction of the first guide rail.
Further, the first bearing table comprises a first flat plate and a first vertical plate, the upper ends of the first flat plate and the first vertical plate are connected, and the second driving piece is in driving connection with the first vertical plate.
Further, the second plummer includes second flat board and second riser, and the upper end of second flat board and second riser is connected, dodges the mouth setting on the second flat board, and the lower extreme and the support body of second riser are connected, and when first plummer was located the second and bears the weight of the position, the upper surface of first plummer was not higher than the upper surface of second flat board.
Further, the ferry mechanism also comprises a base, and the ferry frame is movably arranged on the base along the first horizontal direction.
Further, the ferrying mechanism also comprises a driving belt extending along the first horizontal direction, the driving belt is arranged on the base, the first driving piece is in driving connection with the driving belt, and the driving belt is in driving connection with the ferrying frame; and/or the ferry mechanism further comprises a second guide rail and a second sliding groove, wherein the second guide rail extends along the first horizontal direction, the second guide rail is arranged on the ferry frame, the second sliding groove is arranged on the base, and the second sliding groove is movably arranged on the second guide rail along the extending direction of the second guide rail.
Further, the upper surface of the first bearing table is of a rectangular structure, and the extending direction of the long side of the first bearing table is the same as the first horizontal direction; the ferry frame has first ferry position and second ferry position on first horizontal direction, transfer frame has first transfer position and second transfer position on the second horizontal direction, second ferry position and second transfer position coincide in the horizontal direction, when the ferry frame is located first ferry position, the tongs can remove to the top of first plummer and place medical consumable, when the ferry frame is located second ferry position, and first plummer is located first plummer, the tongs can remove to the top of first plummer and snatch medical consumable, when first plummer is located dodges the position, and transfer frame is located first transfer position, the tongs can place medical consumable on the transfer frame, when transfer frame is located second transfer position, can carry out the filling operation to the medical consumable on the transfer frame.
According to another aspect of the present invention, there is provided a nucleic acid detection integrated machine including a reagent preparing apparatus for preparing an extraction reagent and an amplification reagent, a test object extracting apparatus for extracting an analyte from a sample and combining the analyte with the amplification reagent to form a measurement mixture, and an amplification detecting apparatus for performing amplification detection on the measurement mixture, the test object extracting apparatus including the medical consumable transfer apparatus provided above.
According to the technical scheme, the medical consumable transfer device comprises a ferrying mechanism, a transfer mechanism and a grabbing mechanism, medical consumables are placed on a first bearing table located at a first bearing position, a first driving piece is used for driving the ferrying frame to be close to a grabbing hand in the first horizontal direction, when the first bearing table moves to the lower side of the grabbing hand, the grabbing hand is used for grabbing the medical consumables on the first bearing table, a second driving piece is used for driving the first bearing table to descend to an avoidance position, a third driving piece is used for driving the transfer frame to be close to the grabbing hand in the second horizontal direction, when the transfer frame moves to the upper side of the first bearing table, the grabbing hand is used for placing the medical consumables on the transfer frame, and when the transfer frame is used for driving the transfer frame to be far away from the grabbing hand in the second horizontal direction, the medical consumables are transferred from the ferrying frame to the transfer frame by the grabbing hand. Therefore, the movement of the first bearing table between the first bearing position and the avoidance position, the movement of the ferry frame along the first horizontal direction and the movement of the transfer frame along the second horizontal direction are utilized, so that the gripper can transfer medical consumables between the ferry frame and the transfer frame only by simple grabbing and placing, the movement stroke of the gripper is simplified, and the transfer efficiency of the medical consumables is improved.
Drawings
The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this specification, illustrate embodiments of the application and together with the description serve to explain the application. In the drawings:
Fig. 1 shows a schematic structural view of a ferrying mechanism of a medical consumable transfer device according to an embodiment of the present invention;
FIG. 2 shows a schematic structural view of another view of a ferrying mechanism of a medical consumable transfer device according to an embodiment of the present invention;
FIG. 3 is a schematic view of a ferrying mechanism of a medical consumable transfer device according to an embodiment of the present invention;
FIG. 4 shows a schematic structural view of a ferrying mechanism for placing an amplification plate on a medical consumable transfer apparatus provided according to an embodiment of the present invention;
FIG. 5 shows a schematic structural view of a ferrying mechanism for placing an amplification plate-and-frame membrane in a medical consumable transfer device provided in accordance with an embodiment of the present invention;
FIG. 6 shows a schematic structural view of a ferrying mechanism for placing an extraction plate on a medical consumable transfer device provided according to an embodiment of the present invention;
FIG. 7 is a schematic view showing the structure of a first carrying platform for placing an amplification plate frame membrane on a medical consumable transfer apparatus according to an embodiment of the present invention;
FIG. 8 illustrates a top view of an amplification plate frame membrane placed on a first carrier stage of a medical consumable transfer apparatus provided in accordance with an embodiment of the present invention;
Fig. 9 is a schematic structural view of a first carrying platform of the medical consumable transfer device according to the embodiment of the present invention.
Wherein the above figures include the following reference numerals:
10. A ferrying mechanism; 11. a ferry frame; 111. a frame body; 112. a second bearing table; 1121. an avoidance port; 1122. a second plate; 1123. a second vertical plate; 121. a first driving member; 122. a second driving member; 13. a first loading table; 131. a first plate; 132. a first vertical plate; 141. a drive gear; 142. a driven rack; 151. a first guide rail; 152. a second guide rail; 16. a base; 17. a transmission belt;
21. an amplification plate; 22. amplifying the plate frame membrane; 23. and (5) extracting the plate.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. The following description of at least one exemplary embodiment is merely exemplary in nature and is in no way intended to limit the invention, its application, or uses. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
As shown in fig. 1 to 9, the embodiment of the invention provides a medical consumable transfer device, which comprises a ferry mechanism 10, a transfer mechanism and a grabbing mechanism, wherein the ferry mechanism 10 comprises a ferry frame 11, a first driving member 121, a second driving member 122 and a first bearing table 13, the first driving member 121 can drive the ferry frame 11 to move along a first horizontal direction, the second driving member 122 can drive the first bearing table 13 to move along a vertical direction relative to the ferry frame 11, the transfer mechanism comprises a transfer frame and a third driving member, the third driving member can drive the transfer frame to move along a second horizontal direction perpendicular to the first horizontal direction, the grabbing mechanism comprises a gripper which can move along the vertical direction and the first horizontal direction, wherein the first bearing table 13 has a first bearing position and an avoidance position lower than the first bearing position, when the first bearing table 13 is located at the first bearing position, the upper surface of the first bearing table 13 is located on the same horizontal plane as the upper surface of the transfer frame, the gripper can move to the first bearing table 13 and can move to the first bearing table 13 when the gripper is located at the first bearing position, and the gripper can move to the first bearing table 13 to the avoidance position, and the gripper can move to the medical consumable.
The medical consumable transfer device provided by the embodiment is applied, the medical consumable transfer device comprises a ferry mechanism 10, a transfer mechanism and a grabbing mechanism, the medical consumable is placed on a first bearing table 13 located at a first bearing position, a first driving piece 121 is used for driving a ferry frame 11 to approach a gripper along a first horizontal direction, when the first bearing table 13 moves to the lower side of the gripper, the first bearing table 13 is grabbed by the gripper, a second driving piece 122 is used for driving the first bearing table 13 to descend to an avoidance position, a third driving piece is used for driving a transfer frame to approach the gripper along a second horizontal direction, when the transfer frame moves to the upper side of the first bearing table 13, the gripper places the medical consumable on the transfer frame, and when the transfer frame is driven by the third driving piece to depart from the gripper along the second horizontal direction, so that the gripper transfers the medical consumable from the ferry frame 11 to the transfer frame. Therefore, the movement of the first bearing table 13 between the first bearing position and the avoiding position, the movement of the ferry frame 11 along the first horizontal direction and the movement of the transfer frame along the second horizontal direction are utilized, so that the gripper can transfer medical consumables between the ferry frame 11 and the transfer frame only by simple grabbing and placing, the movement stroke of the gripper is simplified, and the transfer efficiency of the medical consumables is improved.
As shown in fig. 1 and 3, the ferry frame 11 includes a frame body 111 and a second bearing platform 112, the first driving member 121 can drive the frame body 111 to move along a first horizontal direction, the second bearing platform 112 is disposed on the frame body 111, the second bearing platform 112 has an avoidance port 1121, the first bearing platform 13 is vertically movably disposed through the avoidance port 1121, the first bearing platform 13 further has a second bearing position lower than the first bearing position, and when the first bearing platform 13 is located at the second bearing position, the upper surface of the first bearing platform 13 is not higher than the upper surface of the second bearing platform 112. By adopting the second bearing table 112, when the size of the medical consumable is larger, the bearing area of the medical consumable can be increased by moving the first bearing table 13 to the second bearing position and placing the medical consumable on the second bearing table 112.
In this embodiment, when the first bearing table 13 is located at the second bearing position, the upper surface of the first bearing table 13 and the upper surface of the second bearing table 112 may be on the same horizontal plane, so that the first bearing table 13 and the second bearing table 112 can be utilized to jointly receive medical consumables, and the second bearing position and the avoiding position are on the same horizontal plane.
In other embodiments, when the first bearing table 13 is located at the second bearing position, the upper surface of the first bearing table 13 is lower than the upper surface of the second bearing table 112, and the first bearing table 13 is not used for bearing medical consumables, and only the second bearing table 112 is used for bearing medical consumables.
As shown in fig. 4 to 6, the medical consumable comprises an amplifying plate 21, an amplifying plate frame film 22 and an extracting plate 23, when the first bearing table 13 is located at a first bearing position, the amplifying plate 21 or the amplifying plate frame film 22 is borne by the first bearing table 13, when the first bearing table 13 is located at a second bearing position, the extracting plate 23 is borne by the second bearing table 112, since the height of the extracting plate 23 is greater than that of the amplifying plate 21 and that of the amplifying plate frame film 22, the medical consumable can be grabbed from the same height by a gripper, when the extracting plate 23 is borne, the placing position of the extracting plate 23 is lower than that of the amplifying plate 21 or the amplifying plate frame film 22 by the first bearing table 13, so that the gripper can grab medical consumables with different heights by lowering a fixed height, the movement stroke of the gripper is simplified, and the transferring efficiency of the medical consumable is improved.
As shown in fig. 3, the ferry mechanism 10 further includes a driving gear 141 and a driven rack 142, where the driving gear 141 is rotatably disposed on the ferry frame 11, the second driving member 122 is in driving connection with the driving gear 141, the driven rack 142 extends vertically, and the driven rack 142 is connected with the first bearing table 13. The second driving piece 122 drives the driving gear 141 to rotate, and the driving gear 141 drives the driven rack 142 to move in the vertical direction relative to the ferry frame 11 by utilizing gear engagement transmission, so as to drive the first bearing table 13 to move in the vertical direction relative to the ferry frame 11, so that the first bearing table 13 moves among a first bearing position, an avoidance position and a second bearing position, and the reliability of the movement of the first bearing table 13 is improved.
As shown in fig. 3, the ferry mechanism 10 further includes a first rail 151 extending in the vertical direction, the first rail 151 being provided on the ferry frame 11, and a first runner provided on the first loading table 13, the first runner being provided on the first rail 151 movably in the extending direction of the first rail 151. The reliability of the movement direction of the first loading table 13 is improved by the guiding action of the first guide rail 151 on the first chute.
As shown in fig. 3, the first carrying platform 13 includes a first flat plate 131 and a first vertical plate 132, the first flat plate 131 is connected to an upper end of the first vertical plate 132, and the second driving member 122 is in driving connection with the first vertical plate 132. The first sliding groove is formed in the first vertical plate 132, so that the reliability of the movement direction of the first bearing table 13 can be improved, medical consumables can be placed on the first flat plate 131, and the placement stability of the medical consumables can be improved.
As shown in fig. 3, the second bearing platform 112 includes a second plate 1122 and a second vertical plate 1123, the upper ends of the second plate 1122 and the second vertical plate 1123 are connected, the avoidance port 1121 is provided on the second plate 1122, the lower end of the second vertical plate 1123 is connected to the frame 111, and when the first bearing platform 13 is located at the second bearing position, the upper surface of the first bearing platform 13 is not higher than the upper surface of the second plate 1122. The first guide rail 151 is provided on the second vertical plate 1123, so that the reliability of the movement direction of the first loading table 13 can be improved, the avoiding opening 1121 is provided on the second plate 1122, the medical consumable is placed on the second plate 1122, and the placement stability of the medical consumable can be improved.
As shown in fig. 1, the ferry mechanism 10 further comprises a base 16, and the ferry frame 11 is movably arranged on the base 16 along the first horizontal direction. Through the movement of ferry frame 11 at base 16 for the movement of ferry frame 11 is more steady, avoids medical consumptive material to drop.
As shown in fig. 1, the ferrying mechanism 10 further comprises a driving belt 17 extending in the first horizontal direction, the driving belt 17 is arranged on the base 16, the first driving member 121 is in driving connection with the driving belt 17, and the driving belt 17 is in driving connection with the ferrying frame 11. The first driving piece 121 drives the driving belt 17 to move, drives the ferry frame 11 to move relative to the base 16 along the first horizontal direction, and improves the stability of the movement of the ferry frame 11 by using the driving belt 17.
As shown in fig. 2, the ferry mechanism 10 further includes a second rail 152 extending in the first horizontal direction, the second rail 152 being provided on the ferry frame 11, and a second runner provided on the base 16, the second runner being movably provided on the second rail 152 along the extending direction of the second rail 152. The reliability of the movement direction of the ferry frame 11 is improved by the guiding action of the second guide rail 152 on the second slide groove.
Specifically, the second chute is provided on the frame 111.
As shown in fig. 4 to 6, the upper surface of the first carrying platform 13 has a rectangular structure, and the extending direction of the long side of the first carrying platform 13 is the same as the first horizontal direction. When the first bearing table 13 is located at the first bearing position, the first bearing table 13 is used for bearing the amplification plate 21 or the amplification plate frame film 22, at this time, the long side of the medical consumable on the first bearing table 13 is parallel to the long side of the first bearing table 13, when the first bearing table 13 is located at the second bearing position, the second bearing table 112 is used for bearing the extraction plate 23, at this time, the short side of the medical consumable on the first bearing table 13 is parallel to the long side of the first bearing table 13, so that the gripper can grasp medical consumables with different sizes in a similar telescopic range of the gripper arm, and the structure and the control method of the gripper are simplified. That is, the gripper grips the long side of the amplification plate 21, the long side of the amplification plate frame film 22, or the short side of the extraction plate 23 for transfer.
In this embodiment, the ferry frame 11 has a first ferry position and a second ferry position in the first horizontal direction, the transfer frame has a first transfer position and a second transfer position in the second horizontal direction, the second ferry position and the second transfer position overlap in the horizontal direction, when the ferry frame 11 is located at the first ferry position, the gripper can move to the upper side of the first carrying table 13 and place medical consumables, when the ferry frame 11 is located at the second ferry position and the first carrying table 13 is located at the first carrying position, the gripper can move to the upper side of the first carrying table 13 and grasp medical consumables, when the first carrying table 13 is located at the avoidance position and the transfer frame is located at the first transfer position, the gripper can place medical consumables on the transfer frame, and when the transfer frame is located at the second transfer position, the filling operation can be performed on medical consumables on the transfer frame.
Another embodiment of the present invention provides a nucleic acid detection integrated machine, including a reagent preparation device, a test object extraction device, and an amplification detection device, where the reagent preparation device is used to prepare an extraction reagent and an amplification reagent, the test object extraction device is used to extract an analyte from a sample and combine the analyte with the amplification reagent to form a measurement mixture, and the amplification detection device is used to perform amplification detection on the measurement mixture, and the test object extraction device includes the medical consumable transfer device provided above. Therefore, the nucleic acid detection all-in-one machine provided by the embodiment can also utilize the movement of the first bearing table 13 between the first bearing position and the avoidance position, the movement of the ferry frame 11 along the first horizontal direction and the movement of the transfer frame along the second horizontal direction, so that the gripper can transfer medical consumables between the ferry frame 11 and the transfer frame only by simple grabbing and placing, the movement stroke of the gripper is simplified, and the transfer efficiency of the medical consumables is improved.
The medical consumable transfer device is used for transferring medical consumables between the reagent preparation device and the to-be-detected object extraction device.
Specifically, an extraction reagent and an amplification reagent are prepared by a reagent preparation device, the extraction reagent and the amplification reagent are transported to a sample processing device respectively, the sample processing device mixes and extracts a sample with the extraction reagent, an analyte and the amplification reagent are combined to form a measurement mixture, the measurement mixture is transported to an amplification detection device, and after the analyte in the measurement mixture is amplified, the measurement mixture is analyzed and detected to obtain a detection result of the sample.
It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of exemplary embodiments according to the present application. As used herein, the singular is also intended to include the plural unless the context clearly indicates otherwise, and furthermore, it is to be understood that the terms "comprises" and/or "comprising" when used in this specification are taken to specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof.
The relative arrangement of the components and steps, numerical expressions and numerical values set forth in these embodiments do not limit the scope of the present invention unless it is specifically stated otherwise. Meanwhile, it should be understood that the sizes of the respective parts shown in the drawings are not drawn in actual scale for convenience of description. Techniques, methods, and apparatus known to one of ordinary skill in the relevant art may not be discussed in detail, but are intended to be part of the specification where appropriate. In all examples shown and discussed herein, any specific values should be construed as merely illustrative, and not a limitation. Thus, other examples of the exemplary embodiments may have different values. It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further discussion thereof is necessary in subsequent figures.
In the description of the present invention, it should be understood that the azimuth or positional relationships indicated by the azimuth terms such as "front, rear, upper, lower, left, right", "lateral, vertical, horizontal", and "top, bottom", etc., are generally based on the azimuth or positional relationships shown in the drawings, merely to facilitate description of the present invention and simplify the description, and these azimuth terms do not indicate and imply that the apparatus or elements referred to must have a specific azimuth or be constructed and operated in a specific azimuth, and thus should not be construed as limiting the scope of protection of the present invention; the orientation word "inner and outer" refers to inner and outer relative to the contour of the respective component itself.
Spatially relative terms, such as "above … …," "above … …," "upper surface on … …," "above," and the like, may be used herein for ease of description to describe one device or feature's spatial location relative to another device or feature as illustrated in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "above" or "over" other devices or structures would then be oriented "below" or "beneath" the other devices or structures. Thus, the exemplary term "above … …" may include both orientations "above … …" and "below … …". The device may also be positioned in other different ways (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.
In addition, the terms "first", "second", etc. are used to define the components, and are only for convenience of distinguishing the corresponding components, and the terms have no special meaning unless otherwise stated, and therefore should not be construed as limiting the scope of the present invention.
The above description is only of the preferred embodiments of the present invention and is not intended to limit the present invention, but various modifications and variations can be made to the present invention by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. A medical consumable transfer device, characterized in that the medical consumable transfer device comprises:
the ferry mechanism (10) comprises a ferry frame (11), a first driving piece (121), a second driving piece (122) and a first bearing table (13), wherein the first driving piece (121) can drive the ferry frame (11) to move along a first horizontal direction, and the second driving piece (122) can drive the first bearing table (13) to move along a vertical direction relative to the ferry frame (11);
the transfer mechanism comprises a transfer frame and a third driving piece, and the third driving piece can drive the transfer frame to move along a second horizontal direction perpendicular to the first horizontal direction;
A gripping mechanism including a grip movable in the vertical direction and the first horizontal direction;
The medical consumable transfer rack comprises a first bearing table (13), a second bearing table (13), a gripper and a transfer rack, wherein the first bearing table (13) is provided with a first bearing position and an avoidance position lower than the first bearing position, when the first bearing table (13) is located at the first bearing position, the upper surface of the first bearing table (13) and the upper surface of the transfer rack are located on the same horizontal plane, the gripper can move to the upper side of the first bearing table (13) and grasp medical consumables, when the first bearing table (13) is located at the avoidance position, the transfer rack can move to the upper side of the first bearing table (13), and the gripper can place the medical consumables on the transfer rack.
2. Medical consumable transfer device according to claim 1, characterized in that the ferry frame (11) comprises:
A frame body (111), wherein the first driving piece (121) can drive the frame body (111) to move along the first horizontal direction;
The second plummer (112) is arranged on the frame body (111), the second plummer (112) is provided with an avoidance port (1121), the first plummer (13) is vertically movably arranged on the avoidance port (1121) in a penetrating mode, the first plummer (13) is further provided with a second bearing position lower than the first bearing position, and when the first plummer (13) is positioned at the second bearing position, the upper surface of the first plummer (13) is not higher than the upper surface of the second plummer (112).
3. The medical consumable transfer device according to claim 1, characterized in that the ferrying mechanism (10) further comprises a driving gear (141) and a driven rack (142) which are meshed, the driving gear (141) is rotatably arranged on the ferrying frame (11), the second driving member (122) is in driving connection with the driving gear (141), the driven rack (142) extends vertically, and the driven rack (142) is connected with the first bearing table (13).
4. The medical consumable transfer device according to claim 1, characterized in that the ferrying mechanism (10) further comprises a first guide rail (151) extending in a vertical direction and a first runner, the first guide rail (151) being provided on the ferrying frame (11), the first runner being provided on the first carrying table (13), the first runner being movably provided on the first guide rail (151) in an extending direction of the first guide rail (151).
5. The medical consumable transfer device according to claim 1, wherein the first bearing table (13) comprises a first flat plate (131) and a first vertical plate (132), the first flat plate (131) is connected with the upper end of the first vertical plate (132), and the second driving member (122) is in driving connection with the first vertical plate (132).
6. The medical consumable transfer device according to claim 2, wherein the second bearing table (112) comprises a second flat plate (1122) and a second vertical plate (1123), the second flat plate (1122) is connected with the upper end of the second vertical plate (1123), the avoidance port (1121) is provided on the second flat plate (1122), the lower end of the second vertical plate (1123) is connected with the frame body (111), and when the first bearing table (13) is located at the second bearing position, the upper surface of the first bearing table (13) is not higher than the upper surface of the second flat plate (1122).
7. The medical consumable transfer device according to claim 1, characterized in that the ferrying mechanism (10) further comprises a base (16), the ferrying frame (11) being movably arranged on the base (16) along the first horizontal direction.
8. A medical consumable transfer device according to claim 7, wherein,
The ferry mechanism (10) further comprises a transmission belt (17) extending along the first horizontal direction, the transmission belt (17) is arranged on the base (16), the first driving piece (121) is in driving connection with the transmission belt (17), and the transmission belt (17) is in driving connection with the ferry frame (11); and/or the number of the groups of groups,
The ferry mechanism (10) further comprises a second guide rail (152) extending along the first horizontal direction and a second sliding groove, the second guide rail (152) is arranged on the ferry frame (11), the second sliding groove is arranged on the base (16), and the second sliding groove is movably arranged on the second guide rail (152) along the extending direction of the second guide rail (152).
9. A medical consumable transfer device according to claim 1, wherein,
The upper surface of the first bearing table (13) is of a rectangular structure, and the extending direction of the long side of the first bearing table (13) is the same as the first horizontal direction;
The ferry frame (11) is provided with a first ferry position and a second ferry position in the first horizontal direction, the transfer frame is provided with a first transfer position and a second transfer position in the second horizontal direction, the second ferry position and the second transfer position are overlapped in the horizontal direction, when the ferry frame (11) is positioned at the first ferry position, the gripper can move to the upper part of the first bearing table (13) and place medical consumables, when the ferry frame (11) is positioned at the second ferry position, and the first bearing table (13) is positioned at the first bearing position, the gripper can move to the upper part of the first bearing table (13) and grasp the medical consumables, when the first bearing table (13) is positioned at the avoidance position, and the transfer frame is positioned at the first transfer position, the gripper can place the medical consumables onto the transfer frame, and when the transfer frame is positioned at the second bearing table (13), the second bearing table is positioned at the second transfer position, and the medical consumables can be filled.
10. A nucleic acid detection all-in-one machine, characterized in that it comprises a reagent preparation device for preparing an extraction reagent and an amplification reagent, a test-object extraction device for extracting an analyte from a sample and combining the analyte with the amplification reagent to form an assay mixture, and an amplification detection device for performing amplification detection on the assay mixture, the test-object extraction device comprising the medical consumable transfer device according to any one of claims 1 to 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310104423.7A CN118358947A (en) | 2023-01-19 | 2023-01-19 | Medical consumable transfer device and nucleic acid detection all-in-one machine with same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310104423.7A CN118358947A (en) | 2023-01-19 | 2023-01-19 | Medical consumable transfer device and nucleic acid detection all-in-one machine with same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN118358947A true CN118358947A (en) | 2024-07-19 |
Family
ID=91882909
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310104423.7A Pending CN118358947A (en) | 2023-01-19 | 2023-01-19 | Medical consumable transfer device and nucleic acid detection all-in-one machine with same |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN118358947A (en) |
-
2023
- 2023-01-19 CN CN202310104423.7A patent/CN118358947A/en active Pending
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