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CN118022015B - Purification sterilization device is used in injection production - Google Patents

Purification sterilization device is used in injection production Download PDF

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Publication number
CN118022015B
CN118022015B CN202311848060.4A CN202311848060A CN118022015B CN 118022015 B CN118022015 B CN 118022015B CN 202311848060 A CN202311848060 A CN 202311848060A CN 118022015 B CN118022015 B CN 118022015B
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China
Prior art keywords
bin
sterilization
wall
temperature high
frame
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CN202311848060.4A
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Chinese (zh)
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CN118022015A (en
Inventor
刘正华
陶春梅
朱友伟
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Jiangsu Yangtze River Pharmaceutical Co ltd
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Jiangsu Yangtze River Pharmaceutical Co ltd
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Priority to CN202311848060.4A priority Critical patent/CN118022015B/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023Heat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/26Accessories or devices or components used for biocidal treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10Apparatus features
    • A61L2202/12Apparatus for isolating biocidal substances from the environment
    • A61L2202/121Sealings, e.g. doors, covers, valves, sluices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20Targets to be treated
    • A61L2202/21Pharmaceuticals, e.g. medicaments, artificial body parts
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/85Food storage or conservation, e.g. cooling or drying

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

The invention discloses a purification and sterilization device for injection production, and relates to the field of medical sterilization. The purification and sterilization device for injection production comprises a high-temperature high-pressure sterilization bin and a feeding and discharging preparation bin at two ends of the high-temperature high-pressure sterilization bin, wherein a steam injection frame is arranged on the inner wall of the high-temperature high-pressure sterilization bin, a semi-open material transferring table is rotatably arranged in the feeding and discharging preparation bin, a material carrying frame is arranged in the semi-open material transferring table, and a material tray is arranged on the material carrying frame. This injection production is with purifying sterilization apparatus carries out the material through half open type material platform that changes, effectively reduces the heat and looses, and when the carrier is carried to the drive conveyer belt simultaneously moves forward, fixed rack drive power input ring gear rotates for rotatory main shaft drives the material dish revolution, and the gear takes place the meshing transmission with fixed ring gear to the auxiliary drive of minute axle bottom simultaneously, makes the material dish rotate, realizes that inboard material rotates to the outside, with this realization fully sterilizes, reduces the sterilization time, promotes sterilization effect.

Description

Purification sterilization device is used in injection production
Technical Field
The invention relates to the technical field of medical sterilization, in particular to a purification and sterilization device for injection production.
Background
In the production process of the injection, the injection needs to undergo multiple processes of liquid preparation, filling, packaging, sterilization and packaging, and the sterilization process can adopt two modes of physical sterilization and chemical sterilization, and the chemical sterilization mostly adopts ethylene oxide gas, but has high cost and troublesome tail gas treatment, so that the injection is realized by adopting physical sterilization through high-temperature and high-pressure steam in the market at present.
Most pharmaceutical manufacturers now carry out sterilization by setting up a sterilization production line, placing packaged injection on a material rack, pushing the material rack to the inside of a high-temperature high-pressure sterilization bin for sterilization, in order to increase the rate, placing the material rack on the material rack in a densely stacked manner, sterilizing the injection bottle surface by arranging steam generators on two sides or at the top of the high-temperature high-pressure sterilization bin, wherein the disadvantage of densely stacking is that the materials are too concentrated, so that the sterilization effect of the outer side materials is good, the sterilization effect of the inner side is poor, the high-temperature high-pressure sterilization process recommended by the industry is 121 ℃ for 20min, but because the materials are densely stacked, the problem that the original temperature of the materials is low and the heating time is needed is not considered under the existing steam temperature maintenance, and further the sterilization time is needed to be prolonged, so that the whole sterilization process occupies more time, the production rate is lower during production, and a large amount of high-temperature and high-heat steam is emitted outwards in the process of the material entering and exiting the high-temperature high-pressure sterilization bin, so that energy loss is caused, and the problem is solved for the purification sterilization device for injection production.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides a purification and sterilization device for injection production, which solves the problems that the prior industry adopts a mode of densely stacking materials on a material rack and then placing the materials in a high-temperature high-pressure sterilization bin for steam sterilization, the sterilization time is required to be further prolonged due to densely stacking the materials, and a large amount of high-temperature high-heat steam is emitted outwards in the process of feeding and discharging the materials into the high-temperature high-pressure sterilization bin, so that energy loss is caused.
In order to achieve the above purpose, the invention is realized by the following technical scheme: the purification and sterilization device for injection production comprises a high-temperature high-pressure sterilization bin and feeding and discharging preparation bins arranged at two ends of the high-temperature high-pressure sterilization bin, wherein a steam injection frame is arranged on the inner wall of the high-temperature high-pressure sterilization bin, a semi-open material transferring table is rotatably arranged in the feeding and discharging preparation bin, a material carrying frame is arranged in the semi-open material transferring table, and the material carrying frame comprises;
The sliding carrier plate is arranged in the semi-open material transferring table in a sliding manner;
A rotating spindle rotatably disposed on the sliding carrier plate;
The material trays are arranged on the outer wall of the rotary main shaft in an annular array;
a driving conveyer belt is arranged in the high-temperature high-pressure sterilization bin and used for conveying the material carrying frame;
The high-temperature high-pressure sterilization bin is internally provided with a fixed rack which is used for driving the rotary main shaft to rotate, and the rotation process of the rotary main shaft drives the plurality of material trays to rotate.
Preferably, the material carrying rack further comprises;
The support frame is fixedly arranged on the outer wall of the rotary main shaft;
The split shaft is rotatably arranged at the end part of the supporting frame, and the material disc is fixedly sleeved on the outer surface of the split shaft;
The connecting frame is fixedly arranged at the top end of the rotary main shaft, and the split shaft is rotationally connected to the bottom of the connecting frame.
Preferably, a transmission mechanism is arranged at the top of the sliding carrier plate, and the transmission mechanism comprises;
The power input toothed ring is rotatably arranged at the top of the sliding carrier plate, and the outer wall of the power input toothed ring is meshed with the fixed rack;
The main driving gear is fixedly arranged on the outer wall of the bottom end of the rotary main shaft;
The transmission gear is rotatably arranged at the top of the sliding carrier plate, and two sides of the transmission gear are respectively meshed with the inner wall of the power input toothed ring and the outer wall of the main driving gear;
The auxiliary driving gear is fixedly arranged at the bottom end of the split shaft;
The fixed inner gear ring is arranged above the power input gear ring and is meshed with the auxiliary driving gear.
Preferably, the semi-open transfer table comprises;
the rotating table is rotatably arranged in the feeding and discharging preparation bin;
The driving motor is arranged at the top part in the feeding and discharging preparation bin, and the output end of the driving motor is fixedly connected with the rotating table;
The supporting seat is fixedly arranged at the inner bottom of the feeding and discharging preparation bin, and the rotating table is rotatably arranged at the top of the supporting seat.
Preferably, a sealing frame is arranged between the high-temperature high-pressure sterilization bin and the material inlet and outlet preparation bin, the outer wall of the rotating table is attached to the sealing frame, an inflatable sealing rubber strip is arranged on the inner wall of the sealing frame, the inflatable sealing rubber strip abuts against the outer wall of the rotating table, and a sealing bin door is arranged at the end part of the material inlet and outlet preparation bin.
Preferably, an air pump is installed at the top of the high-temperature high-pressure sterilization bin, the output end of the air pump is communicated with the inflatable sealing rubber strip, a steam generator is installed on the back surface of the high-temperature high-pressure sterilization bin and is connected with a steam injection frame, and a plurality of air nozzles are arranged on the outer wall of the steam injection frame.
Preferably, an inclined water guide groove is formed in the inner bottom of the high-temperature high-pressure sterilization bin, a water storage groove is formed in the lower portion of the middle of the inclined water guide groove, a water tank is installed on the outer wall of the high-temperature high-pressure sterilization bin, one end of the water tank is connected with the steam generator, a circulating water pump is installed on the other side of the water tank, the input end of the circulating water pump is connected with the water storage groove, a plc controller is installed on the outer wall of the high-temperature high-pressure sterilization bin, and the plc controller is in control connection with the circulating water pump and the steam generator.
Preferably, the top of supporting seat has seted up the ring channel, the inside of ring channel is provided with the ball, holding ring and holding ring are installed respectively at the upper and lower both ends of rolling table, the holding ring rotates to be connected in the interior roof of advance the material preparation storehouse of going out, the holding ring rotates the inside that sets up at the ring channel.
Preferably, the spout has been seted up to the interior bottom of rolling table, the top of spout is provided with the pushing plate, the pushing plate is used for promoting the outside removal of slip carrier plate, the bottom rotation of spout is provided with the drive lead screw, the bottom fixedly connected with carriage of pushing plate, carriage and drive lead screw threaded connection, servo motor is installed to the one end of drive lead screw, servo motor installs in the interior diapire of rolling table.
Preferably, the bottom welding of fixed ring gear has the back shaft, the bottom fixed connection of back shaft is at slip support plate top, one side of fixed ring gear just to the fixed rack is provided with the cutting plane, the bottom of slip support plate is provided with the straight-line gyro wheel, anti-skidding draw-in groove has been seted up at the top of drive conveyer belt, straight-line gyro wheel joint is in the inside of anti-skidding draw-in groove.
The purification and sterilization device for producing injection disclosed by the invention has the following beneficial effects:
1. This injection production is with purifying sterilization apparatus, inside the rolling table of carrying the work or material rest propelling movement to one end, push away the work or material rest to the drive conveyer belt through the flitch, make the inline gyro wheel card go into the inside zonulae occludens of antiskid draw-in groove, the drive conveyer belt carries the carrying work or material rest and reciprocates, jet the material through the air nozzle on the steam injection frame, when fixed rack and power input ring gear contact, along with carrying the work or material rest and following the drive conveyer belt and move forward, power input ring gear rotates this moment, make rotatory main shaft rotate, drive a plurality of material trays and revolve, the vice driving gear of minute axle bottom takes place the meshing transmission with fixed ring gear simultaneously, make the material tray rotate, realize inboard material rotation to the outside, thereby realize abundant sterilization, reduce the sterilization time, promote sterilization effect.
2. This injection production is with purifying sterilization device, semi-open formula material platform rotation 180 degrees realizes carrying the work or material rest and flows between high temperature high pressure sterilization storehouse and business turn over material preparation storehouse, the high temperature high pressure sterilization storehouse opening of circulation process is little, the temperature loss is little, and after the material enters into high temperature high pressure sterilization storehouse, through starting the air pump, make the air pump aerify to the inside of inflatable joint strip, make inflatable joint strip fill, the gap between seal frame and the revolving stage is plugged up, steam and temperature leak appear when avoiding carrying out high temperature sterilization, and the material in-process of coming out, need close the sealed bin door at both ends, and part high temperature steam enters into the material preparation storehouse of coming out along with the revolving stage, be used for carrying out preheating to the material of material that waits the pan feeding, improve the utilization ratio of high temperature steam, further shorten the required time of material sterilization.
3. This purification sterilization device is used in injection production, the ring channel has been seted up at the top of supporting seat, the inside of ring channel is provided with the ball, locating ring and supporting ring are installed respectively at the upper and lower both ends of rolling stand, the locating ring rotates to be connected in the interior roof in advance storehouse of business turn over material, the supporting ring rotates the inside that sets up at the ring channel, when driving motor drives the rolling stand rotation, prevents that the revolving stage from taking place to incline, the ball can play the effect of effectively reducing friction resistance simultaneously.
Drawings
In order to more clearly illustrate the embodiments of the invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the invention, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of the overall frontal structure of the present invention;
FIG. 2 is a schematic view of the overall rear structure of the present invention;
FIG. 3 is a schematic view of the internal structure of the material feeding and discharging preparation bin of the invention;
FIG. 4 shows the high temperature and high pressure of the present invention a cross section of the internal structure of the sterilization bin;
FIG. 5 is a schematic view of the outer surface structure of a semi-open transfer table according to the present invention;
FIG. 6 is a schematic view of the structure of the outer surface of the material carrying frame of the present invention;
FIG. 7 is an exploded view of the bottom structure of the carrier of the present invention;
FIG. 8 is a cross-sectional view of the internal structure of the feed and discharge preparation bin of the invention;
Fig. 9 is a cross-sectional view of the bottom structure of the high temperature high pressure sterilization chamber of the present invention.
In the figure: 1. a high-temperature high-pressure sterilization bin; 2. feeding and discharging a preparation bin; 3. sealing the bin gate; 4. a plc controller; 5. an air pump; 6. a steam generator; 7. a water tank; 8. a semi-open material transferring table; 81. a rotating table; 82. a driving motor; 83. a positioning ring; 84. a support ring; 85. a support base; 86. an annular groove; 87. a ball; 88. a chute; 89. a servo motor; 810. a pushing plate; 811. a carriage; 812. driving a screw rod; 9. a material carrying frame; 91. sliding the carrier plate; 92. an in-line roller; 93. a transmission mechanism; 931. a power input toothed ring; 932. a main drive gear; 933. a transmission gear; 934. fixing the inner gear ring; 935. a secondary drive gear; 936. a support shaft; 937. cutting a plane; 94. rotating the main shaft; 95. a connecting frame; 96. splitting; 97. a material tray; 98. a support frame; 10. a circulating water pump; 11. a sealing frame; 12. driving the conveyor belt; 13. a fixed rack; 14. a steam spraying frame; 15. an air nozzle; 16. an anti-slip clamping groove; 17. a sloping water guide channel; 18. a water storage tank; 19. and (5) inflating the sealing rubber strip.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more clear, the technical solutions in the embodiments of the present invention are clearly and completely described, and it is obvious that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The embodiment of the application solves the problems that a large amount of high-temperature steam is emitted outwards to cause energy loss in the process of feeding and discharging materials into and out of a high-temperature high-pressure sterilization bin due to the fact that materials are densely stacked and the sterilization time is further required to be prolonged in a steam sterilization mode by arranging the materials on a material rack in a densely stacked mode and then arranging the materials in the high-temperature high-pressure sterilization bin in the current industry.
In order to better understand the above technical solutions, the following detailed description will refer to the accompanying drawings and specific embodiments.
The embodiment of the invention discloses a purification and sterilization device for injection production.
According to the drawings 1-9, the high-temperature high-pressure sterilizing device comprises a high-temperature high-pressure sterilizing bin 1 and a feeding and discharging preparation bin 2 arranged at two ends of the high-temperature high-pressure sterilizing bin 1, wherein a steam injection frame 14 is arranged on the inner wall of the high-temperature high-pressure sterilizing bin 1, a semi-open material transferring table 8 is rotatably arranged in the feeding and discharging preparation bin 2, a material carrying frame 9 is arranged in the semi-open material transferring table 8, and the material carrying frame 9 comprises;
a slide carrier 91 slidably provided in the half-open transfer table 8;
a rotating spindle 94 rotatably provided on the slide carrier 91;
A plurality of material trays 97 arranged in an annular array on the outer wall of the rotary spindle 94;
a driving conveyer belt 12 is arranged in the high-temperature high-pressure sterilizing bin 1 and is used for conveying the material carrying frame 9;
the inside of the high temperature and high pressure sterilizing chamber 1 is provided with a fixed rack 13 which is used for driving the rotary main shaft 94 to rotate, and the rotary main shaft 94 is driven to rotate to drive the plurality of material trays 97 to rotate.
The material carrying frame 9 also comprises;
a supporting frame 98 fixedly installed to the outer wall of the rotating main shaft 94;
The split shaft 96 is rotatably arranged at the end part of the supporting frame 98, and the material disc 97 is fixedly sleeved on the outer surface of the split shaft 96;
The connecting frame 95 is fixedly arranged at the top end of the rotary main shaft 94, and the split shaft 96 is rotatably connected to the bottom of the connecting frame 95.
A transmission mechanism 93 is arranged at the top of the sliding carrier plate 91, and the transmission mechanism 93 comprises;
A power input toothed ring 931 rotatably provided on the top of the slide carrier 91, an outer wall of the power input toothed ring 931 being engaged with the fixed rack 13;
a main driving gear 932 fixedly mounted to a bottom end outer wall of the rotating main shaft 94;
a transmission gear 933 rotatably provided at the top of the slide carrier 91, both sides of the transmission gear 933 being engaged with the inner wall of the power input toothed ring 931 and the outer wall of the main driving gear 932, respectively;
a sub-driving gear 935 fixedly mounted to the bottom end of the split shaft 96;
A fixed ring gear 934 provided above the power input ring gear 931, the fixed ring gear 934 being meshed with the secondary driving gear 935.
The semi-open material transferring table 8 comprises;
a rotating table 81 rotatably provided inside the feed/discharge preparation chamber 2;
The driving motor 82 is arranged at the top in the feeding and discharging preparation bin 2, and the output end of the driving motor 82 is fixedly connected with the rotating table 81;
The supporting seat 85 is fixedly arranged at the inner bottom of the material inlet and outlet preparation bin 2, and the rotating table 81 is rotatably arranged at the top of the supporting seat 85.
A sealing frame 11 is arranged between the high-temperature high-pressure sterilization bin 1 and the feeding and discharging preparation bin 2, the outer wall of the rotating table 81 is attached to the sealing frame 11, an inflatable sealing adhesive tape 19 is arranged on the inner wall of the sealing frame 11, the inflatable sealing adhesive tape 19 abuts against the outer wall of the rotating table 81, a sealing bin door 3 is arranged at the end part of the feeding and discharging preparation bin 2, the inflatable sealing adhesive tape 19 is inflated through an air pump 5 to realize filling, and the sealing effect is enhanced by blocking the rotating table 81 and the sealing frame 11.
The top of the high-temperature high-pressure sterilization bin 1 is provided with an air pump 5, the output end of the air pump 5 is communicated with an inflatable sealing rubber strip 19, the back surface of the high-temperature high-pressure sterilization bin 1 is provided with a steam generator 6, the steam generator 6 is connected with a steam injection frame 14, and the outer wall of the steam injection frame 14 is provided with a plurality of air nozzles 15.
The inner bottom of the high-temperature high-pressure sterilization bin 1 is provided with an inclined water guide groove 17, a water storage groove 18 is arranged below the middle part of the inclined water guide groove 17, the water tank 7 is arranged on the outer wall of the high-temperature high-pressure sterilization bin 1, one end of the water tank 7 is connected with the steam generator 6, the circulating water pump 10 is arranged on the other side of the water tank 7, the input end of the circulating water pump 10 is connected with the water storage groove 18, the plc controller 4 is arranged on the outer wall of the high-temperature high-pressure sterilization bin 1, and the plc controller 4 is in control connection with the circulating water pump 10 and the steam generator 6.
An annular groove 86 is formed in the top of the supporting seat 85, balls 87 are arranged in the annular groove 86, a positioning ring 83 and a supporting ring 84 are respectively arranged at the upper end and the lower end of the rotating table 81, the positioning ring 83 is rotationally connected in the inner top wall of the feeding and discharging preparation bin 2, and the supporting ring 84 is rotationally arranged in the annular groove 86.
The spout 88 has been seted up to the interior bottom of rolling stand 81, and the top of spout 88 is provided with the pushing plate 810, and the pushing plate 810 is used for promoting the outside removal of slip carrier plate 91, and the bottom rotation of spout 88 is provided with drive lead screw 812, and the bottom fixedly connected with carriage 811 of pushing plate 810, carriage 811 and drive lead screw 812 threaded connection, servo motor 89 is installed to the one end of drive lead screw 812, and servo motor 89 installs in the interior diapire of rolling stand 81.
The bottom welding of fixed ring gear 934 has back shaft 936, the bottom fixed connection of back shaft 936 is at the slip carrier plate 91 top, the fixed ring gear 934 just is provided with cutting plane 937 to the one side of fixed rack 13, the bottom of slip carrier plate 91 is provided with straight-line gyro wheel 92, anti-skidding draw-in groove 16 has been seted up at the top of drive conveyer belt 12, straight-line gyro wheel 92 joint is in anti-skidding draw-in groove 16's inside, the design of here anti-skidding draw-in groove 16 and straight-line gyro wheel 92 is the same with elevator and shopping cart pulley design in the supermarket, the bottom of anti-skidding draw-in groove 16 is the shrink form, can make both zonulae occludens because gravity and frictional force after straight-line gyro wheel 92 card goes into anti-skidding draw-in groove 16 inside.
The working principle is as follows; when the device is used, materials to be sterilized are placed on a material tray 97, then a material carrying frame 9 is pushed into a rotating table 81 at one end, at the moment, a sliding carrier plate 91 is attached to two sides of the inner wall of the rotating table 81, tight positioning is achieved, then a sealing bin door 3 is closed, at the moment, a driving motor 82 is started, the driving motor 82 drives the rotating table 81 to rotate 180 degrees, at the moment, an opening of the rotating table 81 is inwards, a servo motor 89 is started, the servo motor 89 drives a driving screw rod 812 to rotate, so that a material pushing plate 810 slides outwards along a sliding groove 88, the material carrying frame 9 is pushed out of the rotating table 81, at the moment, the material carrying frame 9 slides onto a driving conveying belt 12, and an in-line roller 92 is automatically inserted into an anti-slip clamping groove 16, at the moment, the anti-slip clamping groove 16 and an in-line roller 92 are designed to be identical with an elevator and a shopping cart pulley in a supermarket, at the moment, the bottom end of the anti-slip clamping groove 16 is in a contracted shape, and after the in-line roller 92 is clamped into the anti-slip clamping groove 16, the inner part can enable the two to be tightly connected due to gravity and friction force;
At this time, the conveying belt 12 is driven to move forward to carry the material carrying frame 9, at this time, the steam generator 6 is started by the plc controller 4, the material is sprayed by the air nozzle 15 on the steam spraying frame 14, high-temperature steam sterilization is realized, when the fixed rack 13 is contacted with the power input toothed ring 931, the power input toothed ring 931 rotates along with the material carrying frame 9 moving forward along with the conveying belt 12, and the main driving gear 932 is driven to rotate by the transmission gear 933, at this time, the rotating main shaft 94 rotates, so that the plurality of material discs 97 are driven to revolve by the supporting frame 98 by taking the rotating main shaft 94 as an axis, when the material discs 97 revolve, the auxiliary driving gear 935 at the bottom end of the split shaft 96 is meshed with the fixed inner gear 934, so that the split shaft 96 drives the material discs 97 on the surface of the split shaft to rotate, so that the material on the outer surface of the whole material carrying frame 9 revolves to realize external sterilization, and simultaneously all the material discs 97 on the carrying frame 9 revolve, so that the material on the inner side rotates to the outer side, thereby realizing full sterilization, and the sterilization time is reduced, and sterilization effect is improved;
when the material carrying frame 9 moves to the tail end, the semi-open material rotating table 8 at the tail end rotates inwards by 180 degrees, at the moment, the conveying belt 12 is driven to push the material carrying frame 9 into the rotating table 81, then the rotating table 81 continues to rotate by 180 degrees, the material carrying frame 9 is transferred into the material inlet and outlet preparation bin 2at the other end, in the process, materials continuously enter the high-temperature high-pressure sterilization bin 1 for sterilization, after the materials enter the high-temperature high-pressure sterilization bin 1, the air pump 5 is started to enable the air pump 5 to inflate the inside of the inflatable sealing rubber strip 19, the inflatable sealing rubber strip 19 fills up a gap between the sealing frame 11 and the rotating table 81, steam and temperature leakage are avoided when high-temperature sterilization is carried out, in the material inlet and outlet process, the sealing bin doors 3 at the two ends need to be closed, and part of high-temperature steam enters the material inlet and outlet preparation bin 2 along with the rotating table 81 for preheating the materials to be fed.
The foregoing has shown and described the basic principles and main features of the present invention and the advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and that the above embodiments and descriptions are merely illustrative of the principles of the present invention, and various changes and modifications may be made without departing from the spirit and scope of the invention, which is defined in the appended claims. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (7)

1. The purification and sterilization device for injection production comprises a high-temperature high-pressure sterilization bin (1) and a feeding and discharging preparation bin (2) arranged at two ends of the high-temperature high-pressure sterilization bin (1), and is characterized in that a steam injection frame (14) is arranged on the inner wall of the high-temperature high-pressure sterilization bin (1), a semi-open material transferring table (8) is rotatably arranged in the feeding and discharging preparation bin (2), a material carrying frame (9) is arranged in the semi-open material transferring table (8), and the material carrying frame (9) comprises; a sliding carrier plate (91) which is arranged in the semi-open material transferring table (8) in a sliding way; a rotating spindle (94) rotatably provided on the slide carrier plate (91); the material trays (97) are arranged on the outer wall of the rotary main shaft (94) in an annular array; a driving conveyer belt (12) is arranged in the high-temperature high-pressure sterilization bin (1) and is used for conveying a material carrying frame (9); a fixed rack (13) is arranged in the high-temperature high-pressure sterilization bin (1) and is used for driving a rotary main shaft (94) to rotate, and the rotary main shaft (94) is driven to rotate in a rotary process to drive a plurality of material trays (97) to rotate;
The material carrying frame (9) also comprises; a support frame (98) fixedly mounted on the outer wall of the rotary spindle (94); the split shaft (96) is rotatably arranged at the end part of the supporting frame (98), and the material disc (97) is fixedly sleeved on the outer surface of the split shaft (96); the connecting frame (95) is fixedly arranged at the top end of the rotary main shaft (94), and the split shaft (96) is rotatably connected to the bottom of the connecting frame (95);
A transmission mechanism (93) is arranged at the top of the sliding carrier plate (91), and the transmission mechanism (93) comprises; a power input toothed ring (931) rotatably provided on the top of the slide carrier plate (91), the outer wall of the power input toothed ring (931) being engaged with the fixed rack (13); a main driving gear (932) fixedly mounted to a bottom end outer wall of the rotating main shaft (94); the transmission gear (933) is rotatably arranged at the top of the sliding carrier plate (91), and two sides of the transmission gear (933) are respectively meshed with the inner wall of the power input toothed ring (931) and the outer wall of the main driving gear (932); a secondary drive gear (935) fixedly mounted to the bottom end of the split shaft (96); a fixed ring gear (934) disposed above the power input ring gear (931), the fixed ring gear (934) being meshed with the secondary driving gear (935);
The semi-open material transferring table (8) comprises; a rotating table (81) rotatably provided in the feed/discharge preparation bin (2); the driving motor (82) is arranged at the inner top of the feeding and discharging preparation bin (2), and the output end of the driving motor (82) is fixedly connected with the rotating table (81); the supporting seat (85) is fixedly arranged at the inner bottom of the feeding and discharging preparation bin (2), and the rotating table (81) is rotatably arranged at the top of the supporting seat (85).
2. The purification and sterilization apparatus for producing an injection according to claim 1, wherein: a sealing frame (11) is arranged between the high-temperature high-pressure sterilization bin (1) and the feeding and discharging preparation bin (2), the outer wall of the rotating table (81) is attached to the sealing frame (11), an inflatable sealing rubber strip (19) is arranged on the inner wall of the sealing frame (11), the inflatable sealing rubber strip (19) abuts against the outer wall of the rotating table (81), and a sealing bin door (3) is arranged at the end part of the feeding and discharging preparation bin (2).
3. The purification and sterilization apparatus for producing an injection according to claim 2, wherein: the high-temperature high-pressure sterilizing bin is characterized in that an air pump (5) is arranged at the top of the high-temperature high-pressure sterilizing bin (1), the output end of the air pump (5) is communicated with an inflatable sealing rubber strip (19), a steam generator (6) is arranged on the back surface of the high-temperature high-pressure sterilizing bin (1), the steam generator (6) is connected with a steam spraying frame (14), and a plurality of air nozzles (15) are arranged on the outer wall of the steam spraying frame (14).
4. A purification and sterilization apparatus for injection production according to claim 3, wherein: the inner bottom of the high-temperature high-pressure sterilization bin (1) is provided with an inclined water guide groove (17), a water storage groove (18) is arranged below the middle of the inclined water guide groove (17), a water tank (7) is arranged on the outer wall of the high-temperature high-pressure sterilization bin (1), one end of the water tank (7) is connected with a steam generator (6), a circulating water pump (10) is arranged on the other side of the water tank (7), the input end of the circulating water pump (10) is connected with the water storage groove (18), a plc controller (4) is arranged on the outer wall of the high-temperature high-pressure sterilization bin (1), and the plc controller (4) is in control connection with the circulating water pump (10) and the steam generator (6).
5. The purification and sterilization apparatus for producing an injection according to claim 4, wherein: annular groove (86) has been seted up at the top of supporting seat (85), the inside of annular groove (86) is provided with ball (87), holding ring (83) and holding ring (84) are installed respectively at the upper and lower both ends of rolling table (81), holding ring (83) rotate and connect in the interior roof of advance storehouse (2) of feeding and discharging, holding ring (84) rotate the inside that sets up at annular groove (86).
6. The purification and sterilization apparatus for producing an injection according to claim 5, wherein: spout (88) have been seted up to the interior bottom of rolling table (81), the top of spout (88) is provided with pushing away flitch (810), pushing away flitch (810) are used for promoting outside removal of slip carrier plate (91), the bottom rotation of spout (88) is provided with drive lead screw (812), the bottom fixedly connected with carriage (811) of pushing away flitch (810), carriage (811) and drive lead screw (812) threaded connection, servo motor (89) are installed to the one end of drive lead screw (812), servo motor (89) are installed in the interior bottom wall of rolling table (81).
7. The purification and sterilization apparatus for producing an injection according to claim 6, wherein: the bottom welding of fixed ring gear (934) has back shaft (936), the bottom fixed connection of back shaft (936) is at slip carrier plate (91) top, one side of fixed ring gear (934) just to fixed rack (13) is provided with cutting plane (937), the bottom of slip carrier plate (91) is provided with straight-line gyro wheel (92), anti-skidding draw-in groove (16) have been seted up at the top of drive conveyer belt (12), straight-line gyro wheel (92) joint is in the inside of anti-skidding draw-in groove (16).
CN202311848060.4A 2023-12-29 2023-12-29 Purification sterilization device is used in injection production Active CN118022015B (en)

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Publication number Priority date Publication date Assignee Title
CN105239347A (en) * 2015-10-31 2016-01-13 成都美饰实业有限责任公司 A sterilizing steam cabinet having a drying function
CN113018485A (en) * 2021-03-25 2021-06-25 徐炳辉 Degassing unit of medical cotton swab production usefulness

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Publication number Priority date Publication date Assignee Title
US4976920A (en) * 1987-07-14 1990-12-11 Adir Jacob Process for dry sterilization of medical devices and materials
ES2492682T3 (en) * 2010-04-28 2014-09-10 Lothar Saiger Procedure for cleaning and disinfection by machine objects
KR102086967B1 (en) * 2019-09-19 2020-03-09 장광양 Rotating type retort sterilization apparatus with basket fixing unit
CN216824196U (en) * 2021-12-27 2022-06-28 沈阳一叁生物科技有限公司 Steam type scalpel degassing unit
CN219921604U (en) * 2023-05-18 2023-10-31 华裕(无锡)制药有限公司 Urapidil hydrochloride injection sterilization device

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105239347A (en) * 2015-10-31 2016-01-13 成都美饰实业有限责任公司 A sterilizing steam cabinet having a drying function
CN113018485A (en) * 2021-03-25 2021-06-25 徐炳辉 Degassing unit of medical cotton swab production usefulness

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