CN117918942A - Quick cryoablation device - Google Patents
Quick cryoablation device Download PDFInfo
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- CN117918942A CN117918942A CN202410196360.7A CN202410196360A CN117918942A CN 117918942 A CN117918942 A CN 117918942A CN 202410196360 A CN202410196360 A CN 202410196360A CN 117918942 A CN117918942 A CN 117918942A
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- air inlet
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- rapid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00577—Ablation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00982—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body combined with or comprising means for visual or photographic inspections inside the body, e.g. endoscopes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0212—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument inserted into a body lumen, e.g. catheter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0231—Characteristics of handpieces or probes
- A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Otolaryngology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
Abstract
The invention relates to the technical field of medical equipment, and discloses a rapid cryoablation device which comprises a rapid cryoablation probe, wherein the rapid cryoablation probe comprises a shell, one end of the shell is fixedly connected with a connecting seat, and the other end of the shell is connected with a freezing head through a pipeline; the cryoablation assembly comprises an air inlet piece and an air return piece, one ends of the air inlet piece and the air return piece respectively extend into the pipeline and are communicated with the freezing head, an air inlet pipeline interface and an air return pipeline interface are arranged on the shell, the other end of the air inlet piece is communicated with the air inlet pipeline interface, and the other end of the air return piece is communicated with the air return pipeline interface; the injection assembly comprises an injection piece, the injection piece is arranged at one end of the air inlet piece, which is close to the freezing head, the air inlet piece is used for converting liquid carbon dioxide into gaseous carbon dioxide through the injection piece, and the air return piece is used for adsorbing the gaseous carbon dioxide; a rapid cryoablation device includes a storage member and an adjustment assembly. The probe realizes rapid ablation freezing and rewarming, and has the advantages of simple structure, easy operation, obvious effect and popularization value.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to a rapid cryoablation device.
Background
Cryoablation is a method for inactivating solid tissues in situ by freezing pathological tissues through a low-temperature technology, and the action principle is that the pathological tissues are rapidly cooled by low temperature to destroy cells, so that cell necrosis or apoptosis is caused, and the aim of treatment is achieved. Cryoablation is a commonly used interventional technique in surgery. Because of the therapeutic principle of cryoablation, the application of the cryoablation in the natural cavity of the human body has the advantages of high safety, small irritation and damage to the wall tissues of the cavity, and difficult complication such as fistula or stenosis. Cryoablation is used under the guidance of an endoscope, is a minimally invasive treatment mode, and is increasingly used.
Cryoablation is widely applied in interventional therapy, and through a low-temperature instrument, focal tissues are subjected to freezing and rewarming processes in a controlled manner, ice crystals are formed in cells of the lesion tissues, so that the cells are dehydrated and shrunken, irreversible damage is caused to the cells, and death of the cells of the lesion tissues is caused, so that the aim of treatment is fulfilled.
In order to meet the effect and efficiency of cryoablation, the probe temperature of cryoablation needs to reach a lower limit temperature and simultaneously reach a faster cooling and heating rate.
Accordingly, there is a need for a rapid cryoablation device that addresses the above-described issues.
Disclosure of Invention
The object of the present invention is to provide a rapid cryoablation device that solves the above-mentioned problems of the prior art.
In order to achieve the above object, the present invention provides the following solutions: the invention provides a rapid cryoablation probe comprising:
the refrigerator comprises a shell, wherein one end of the shell is fixedly connected with a connecting seat, and the other end of the shell is connected with a refrigerating head through a pipeline;
The cryoablation assembly comprises an air inlet piece and an air return piece, one ends of the air inlet piece and the air return piece respectively extend into the pipeline to be communicated with the freezing head, an air inlet pipeline interface and an air return pipeline interface are arranged on the shell, the other end of the air inlet piece is communicated with the air inlet pipeline interface, and the other end of the air return piece is communicated with the air return pipeline interface;
the injection assembly comprises an injection piece, the injection piece is arranged at one end, close to the freezing head, of the air inlet piece, the air inlet piece is used for converting liquid carbon dioxide into gaseous carbon dioxide through the injection piece, and the air return piece is used for adsorbing the gaseous carbon dioxide.
Preferably, the air inlet piece comprises an air inlet pipeline arranged in the middle of the pipeline, one end of the air inlet pipeline is communicated with the air inlet pipeline interface, and the other end of the air inlet pipeline is communicated with the freezing head.
Preferably, the air return piece comprises an air return pipeline arranged between the pipeline and the air inlet pipeline, one end of the air return pipeline is communicated with the air return pipeline interface, and the other end of the air return pipeline is communicated with the freezing head and forms a circulating pipeline with the air inlet pipeline.
Preferably, the injection member comprises an injection head fixedly connected in the air inlet pipeline, an injection hole is formed in the injection head, and the air inlet pipeline is communicated with the freezing head through the injection hole.
Preferably, the connecting seat is fixedly connected with a filter through a jackscrew, and the air inlet pipeline is communicated with the air inlet pipeline interface through the filter.
Preferably, one end of the shell is fixedly connected with a rubber sheath, and the rubber sheath is sleeved on the pipeline.
A rapid cryoablation device comprising:
The storage part is arranged on the support frame, and the air inlet pipeline connector and the air return pipeline connector are communicated with the storage part through connecting pipes;
the adjusting assembly comprises an adjusting piece and a monitoring piece, wherein the adjusting piece and the monitoring piece are respectively arranged on the connecting pipe.
Preferably, the storage part comprises two storage tanks fixedly connected to the support frame, one of the storage tanks is used for storing liquid carbon dioxide, the other storage tank is used for storing gaseous carbon dioxide, the two storage tanks are communicated, the air inlet pipeline interface is communicated with the storage tanks storing the liquid carbon dioxide, and the air return pipeline interface is respectively communicated with the two storage tanks.
Preferably, the adjusting member includes a ball valve mounted on the connection pipe.
Preferably, the monitoring member comprises a pressure gauge mounted on the connection tube.
Compared with the prior art, the invention has the following advantages and technical effects:
1. The invention provides a rapid cryoablation device, which comprises: the air inlet piece is used for conveying liquid carbon dioxide, the conveyed liquid carbon dioxide is converted into gaseous carbon dioxide in the freezing head after passing through the injection piece, the internal temperature of the freezing head is reduced, the gaseous carbon dioxide is conveyed to the outside through the air return piece, and the whole body is circulated, so that the freezing head is quickly cooled.
2. The invention provides a width freezing and ablating device, which is characterized in that the storage and the transportation of gaseous and liquid carbon dioxide are realized through a storage part, the liquid carbon dioxide is transported into an air inlet part and an air return part simultaneously after the temperature reduction is finished, and meanwhile, the internal pressure and the external pressure of the liquid carbon dioxide in the air inlet part and the air return part are regulated through a regulating component, so that the temperature and the pressure of the internal and the external liquid carbon dioxide are the same, the conversion is not performed any more, and the rapid rewarming of a freezing head is realized.
3. The invention provides a width freezing and ablating device which realizes rapid ablation freezing and rewarming, and the probe has the advantages of simple structure, easy operation, obvious effect and popularization value.
Drawings
For a clearer description of an embodiment of the invention or of the solutions of the prior art, the drawings that are needed in the embodiment will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the invention, and that other drawings can be obtained according to these drawings without inventive effort for a person skilled in the art:
FIG. 1 is a schematic diagram of the overall structure of a cryoablation probe of the present invention;
FIG. 2 is a schematic view of the internal structure of the cryoablation probe of the present invention;
FIG. 3 is a schematic view of a spray head according to the present invention;
FIG. 4 is a schematic diagram of the cooling state of the present invention;
FIG. 5 is a schematic view of the overall structure of the cryoablation device of the present invention;
FIG. 6 is a schematic diagram of the temperature recovery state of the present invention;
Wherein, 1, the shell; 2. a connecting seat; 3. a jackscrew; 4. a pipe; 5. a freezing head; 6. an air inlet pipeline interface; 7. an air return pipeline interface; 8. an air intake duct; 9. an air return pipeline; 10. an ejection head; 11. a filter; 12. a rubber sheath; 13. a support frame; 14. a storage tank; 15. a ball valve; 16. a pressure gauge.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In order that the above-recited objects, features and advantages of the present invention will become more readily apparent, a more particular description of the invention will be rendered by reference to the appended drawings and appended detailed description.
Referring to fig. 1-6, the present invention provides a rapid cryoablation probe comprising:
The refrigerator comprises a shell 1, wherein one end of the shell 1 is fixedly connected with a connecting seat 2, and the other end of the shell 1 is connected with a refrigerating head 5 through a pipeline 4;
The cryoablation assembly comprises an air inlet piece and an air return piece, wherein one ends of the air inlet piece and the air return piece respectively extend into the pipeline 4 and are communicated with the freezing head 5, an air inlet pipeline interface 6 and an air return pipeline interface 7 are arranged on the shell 1, the other end of the air inlet piece is communicated with the air inlet pipeline interface 6, and the other end of the air return piece is communicated with the air return pipeline interface 7;
the injection assembly comprises an injection piece, the injection piece is arranged at one end of the air inlet piece, which is close to the freezing head 5, the air inlet piece is used for converting liquid carbon dioxide into gaseous carbon dioxide through the injection piece, and the air return piece is used for adsorbing the gaseous carbon dioxide.
Further optimizing scheme, the air inlet piece is including setting up the air inlet pipe 8 at the interior middle part of pipeline 4, and air inlet pipe 8 one end and air inlet pipe interface 6 intercommunication, air inlet pipe 8 other end and freezing head 5 intercommunication.
The air inlet pipeline 8 is positioned in the middle of the pipeline 4, and the air inlet pipeline 8 is used for conveying liquid carbon dioxide and converting gaseous carbon dioxide through the injection part to cool.
Further optimizing scheme, the return air piece is including setting up the return air pipeline 9 between pipeline 4 and air inlet pipe 8, and return air pipeline 9 one end and return air pipeline interface 7 intercommunication, return air pipeline 9 other end and freezing head 5 intercommunication, and form the circulation pipeline with air inlet pipe 8.
The return air pipe 9 is located outside the air intake pipe 8, and the return air pipe 9 is used for conveying gaseous carbon dioxide to the outside.
Further optimizing scheme, the injection part includes the injection head 10 of fixed connection in air inlet tube 8, has seted up the jet orifice on the injection head 10, and air inlet tube 8 passes through jet orifice and freezing head 5 intercommunication.
Referring to fig. 3, the spray head 10 is fixedly connected to the end of the air inlet pipe 8, the liquid carbon dioxide flows to the spray head 10, the diameter of the spray hole on the spray head 10 is 0.1mm, the liquid carbon dioxide rapidly passes through the spray hole to form spray under the high pressure flow of the liquid carbon dioxide, and the liquid carbon dioxide rapidly gasifies in the surrounding cavity so that the outer shell of the freezing head 5 at the end of the cryoablation probe rapidly reaches below 40 ℃ below zero (less than or equal to 4 seconds), and rapid ablation freezing is realized.
According to a further optimization scheme, a filter 11 is fixedly connected to the connecting seat 2 through the jackscrew 3, and the air inlet pipeline 8 and the air inlet pipeline interface 6 are communicated through the filter 11.
The filter 11 is fixedly connected with the connecting seat 2 through the jackscrew 3, and liquid carbon dioxide at the inlet end is filtered through the filter 11.
In a further optimized scheme, one end of the shell 1 is fixedly connected with a rubber sheath 12, and the rubber sheath 12 is sleeved on the pipeline 4.
The rubber sheath 12 is covered on the pipeline 4 to realize the protection of the pipeline 4.
Referring to fig. 1-4, liquid carbon dioxide in a normal temperature state is taken as a cryoablation medium, flows onto an injection head 10 at the tail end of an air inlet pipeline 8 from an air inlet pipeline interface 6 of the cryoablation probe through the air inlet pipeline 8, rapidly passes through an injection hole under the high-pressure flow of the liquid carbon dioxide to form injection, and rapidly gasifies in a surrounding cavity, so that the shell of a freezing head 5 at the tail end of the cryoablation probe rapidly reaches below 40 ℃ below zero (less than or equal to 4 seconds), and rapid ablation freezing is realized. The gas after the injection gasification returns to the return air pipeline interface 7 of the cryoablation probe through the return air pipeline 9 to form a finished loop, thereby completing a rapid ablation freezing process.
A rapid cryoablation device comprising:
The support frame 13, the support frame 13 is provided with a storage part, and the air inlet pipeline interface 6 and the air return pipeline interface 7 are communicated with the storage part through connecting pipes;
the adjusting component comprises an adjusting piece and a monitoring piece, and the adjusting piece and the monitoring piece are respectively arranged on the connecting pipe.
In a further optimized scheme, the storage part comprises two storage tanks 14 fixedly connected to the support frame 13, one storage tank 14 is used for storing liquid carbon dioxide, the other storage tank 14 is used for storing gaseous carbon dioxide, the two storage tanks 14 are communicated, the air inlet pipeline connector 6 is communicated with the storage tank 14 storing the liquid carbon dioxide, and the air return pipeline connector 7 is respectively communicated with the two storage tanks 14.
Referring to fig. 5 and 6, after the ablation freezing process is finished, the liquid carbon dioxide is respectively introduced into the air inlet pipeline 8 from the air inlet pipeline interface 6 and the air return pipeline 9 from the air return pipeline interface 7 by the storage tank 14 for storing the liquid carbon dioxide, at this time, two paths of liquid carbon dioxide with the same temperature meet in the freezing head 5at the tail end of the pipeline 4, and the temperature and the pressure of the liquid carbon dioxide inside and outside are the same, so that the liquid carbon dioxide in the air inlet pipeline 8 cannot pass through the injection hole, and thus the injection action is not formed any more, and a finished loop cannot be formed. At this time, the outer shell of the freezing head 5 is quickly warmed to zero degree or above (less than or equal to 5 seconds), thereby completing a quick re-warming process.
Further preferably, the adjusting member comprises a ball valve 15 mounted on the connecting tube.
The ball valve 15 is used to control the amount of carbon dioxide delivered.
Further preferably, the monitoring member comprises a pressure gauge 16 mounted on the connecting tube.
The pressure gauge 16 is used for monitoring the carbon dioxide delivery pressure, and ensuring that the pressure of the liquid carbon dioxide in the air inlet pipeline 8 and the pressure of the liquid carbon dioxide in the air return pipeline 9 are consistent.
The invention provides a rapid cryoablation device, which comprises the following specific working processes:
The cooling process comprises the following steps:
Liquid carbon dioxide is conveyed to the air inlet pipeline interface 6 through the storage tank 14, is filtered through the filter 11 in the connecting seat 2, and enters the air inlet pipeline 8 after passing through the filter 11. Wherein, air inlet pipe 8 is 0.7mm diameter stainless steel capillary, and air inlet pipe 8 passes through interference fit to be fixed on pipeline joint 6. The flow of liquid carbon dioxide continues in the inlet line 8 until the end of the injector head 10. At this time, the liquid carbon dioxide does not flow freely as in the air inlet pipeline 8, but flows under high pressure to form injection through the injection hole rapidly, and is gasified rapidly in the cavity of the freezing head 5, so that the temperature in the cavity of the freezing head 5 at the tail end of the cryoablation probe is below 40 ℃ below zero (less than or equal to 4 seconds) rapidly, and rapid ablation and freezing are realized. At this time, in the cavity of the freezing head 5, the gas after the injection gasification returns to the return air pipeline interface 7 of the cryoablation probe through the return air pipeline 9 and is conveyed into the storage tank 14 to form a finished loop, thereby completing a rapid ablation freezing process.
And (3) heating:
After the ablation freezing process is finished, liquid carbon dioxide enters the air inlet pipeline 8 from the air inlet pipeline interface 6 and enters the air return pipeline 9 from the air return pipeline interface 7 respectively from the storage tank 14, at the moment, two paths of liquid carbon dioxide with the same temperature meet in the freezing head 5 at the tail end of the pipeline 4, and the temperature and the pressure of the liquid carbon dioxide inside and outside are the same, so that the liquid carbon dioxide in the air inlet pipeline 8 cannot pass through the injection hole, the injection action is not formed any more, and a finished loop cannot be formed. At this time, the outer shell of the freezing head 5 is quickly warmed to zero degree or above (less than or equal to 5 seconds), thereby completing a quick re-warming process.
Thereby realizing a complete rapid cryoablation and rapid rewarming process. The device can realize rapid ablation freezing and rewarming, and the probe has the advantages of simple structure, easy operation, obvious effect and popularization value.
In the description of the present invention, it should be understood that the terms "longitudinal," "transverse," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like indicate or are based on the orientation or positional relationship shown in the drawings, merely to facilitate description of the present invention, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the present invention.
The above embodiments are only illustrative of the preferred embodiments of the present invention and are not intended to limit the scope of the present invention, and various modifications and improvements made by those skilled in the art to the technical solutions of the present invention should fall within the protection scope defined by the claims of the present invention without departing from the design spirit of the present invention.
Claims (10)
1. A rapid cryoablation probe comprising:
the refrigerator comprises a shell (1), wherein one end of the shell (1) is fixedly connected with a connecting seat (2), and the other end of the shell (1) is connected with a refrigerating head (5) through a pipeline (4);
The cryoablation assembly comprises an air inlet piece and an air return piece, one ends of the air inlet piece and the air return piece extend into the pipeline (4) respectively and are communicated with the freezing head (5), an air inlet pipeline interface (6) and an air return pipeline interface (7) are arranged on the shell (1), the other end of the air inlet piece is communicated with the air inlet pipeline interface (6), and the other end of the air return piece is communicated with the air return pipeline interface (7);
The injection assembly comprises an injection piece, the injection piece is arranged at one end, close to the freezing head (5), of the air inlet piece, the air inlet piece is used for converting liquid carbon dioxide into gaseous carbon dioxide through the injection piece, and the air return piece is used for adsorbing the gaseous carbon dioxide.
2. A rapid cryoablation probe according to claim 1 wherein: the air inlet piece comprises an air inlet pipeline (8) arranged in the middle of the pipeline (4), one end of the air inlet pipeline (8) is communicated with the air inlet pipeline interface (6), and the other end of the air inlet pipeline (8) is communicated with the freezing head (5).
3. A rapid cryoablation probe according to claim 2 wherein: the air return piece comprises an air return pipeline (9) arranged between the pipeline (4) and the air inlet pipeline (8), one end of the air return pipeline (9) is communicated with the air return pipeline interface (7), and the other end of the air return pipeline (9) is communicated with the freezing head (5) and forms a circulating pipeline with the air inlet pipeline (8).
4. A rapid cryoablation probe according to claim 2 wherein: the injection part comprises an injection head (10) fixedly connected in the air inlet pipeline (8), an injection hole is formed in the injection head (10), and the air inlet pipeline (8) is communicated with the freezing head (5) through the injection hole.
5. A rapid cryoablation probe according to claim 2 wherein: the connecting seat (2) is fixedly connected with a filter (11) through a jackscrew (3), and the air inlet pipeline (8) is communicated with the air inlet pipeline interface (6) through the filter (11).
6. A rapid cryoablation probe according to claim 1 wherein: one end of the shell (1) is fixedly connected with a rubber sheath (12), and the rubber sheath (12) is sleeved on the pipeline (4).
7. A rapid cryoablation apparatus adapted for use with a rapid cryoablation probe of claim 1 comprising:
The device comprises a support frame (13), wherein a storage part is arranged on the support frame (13), and the air inlet pipeline interface (6) and the air return pipeline interface (7) are communicated with the storage part through connecting pipes;
the adjusting assembly comprises an adjusting piece and a monitoring piece, wherein the adjusting piece and the monitoring piece are respectively arranged on the connecting pipe.
8. The rapid cryoablation device of claim 7 wherein: the storage piece comprises two storage tanks (14) fixedly connected to the support frame (13), one storage tank (14) is used for storing liquid carbon dioxide, the other storage tank (14) is used for storing gaseous carbon dioxide, the two storage tanks (14) are communicated, the air inlet pipeline interface (6) is communicated with the storage tanks (14) storing the liquid carbon dioxide, and the air return pipeline interface (7) is respectively communicated with the two storage tanks (14).
9. The rapid cryoablation device of claim 7 wherein: the adjusting member comprises a ball valve (15) mounted on the connecting tube.
10. The rapid cryoablation device of claim 7 wherein: the monitoring element comprises a pressure gauge (16) mounted on the connecting tube.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202410196360.7A CN117918942A (en) | 2024-02-22 | 2024-02-22 | Quick cryoablation device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202410196360.7A CN117918942A (en) | 2024-02-22 | 2024-02-22 | Quick cryoablation device |
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| CN117918942A true CN117918942A (en) | 2024-04-26 |
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| CN202410196360.7A Pending CN117918942A (en) | 2024-02-22 | 2024-02-22 | Quick cryoablation device |
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| US20100256621A1 (en) * | 2009-04-06 | 2010-10-07 | Cryomedix Llc | Single phase liquid refrigerant cryoablation system with multitubular distal section and related method |
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