CN1177606C - Medicine for treating gastritis and gastric or duodenal ulcer and its preparing process - Google Patents
Medicine for treating gastritis and gastric or duodenal ulcer and its preparing process Download PDFInfo
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- CN1177606C CN1177606C CNB021380082A CN02138008A CN1177606C CN 1177606 C CN1177606 C CN 1177606C CN B021380082 A CNB021380082 A CN B021380082A CN 02138008 A CN02138008 A CN 02138008A CN 1177606 C CN1177606 C CN 1177606C
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- rhizoma
- medicine
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- duodenal ulcer
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- 239000003814 drug Substances 0.000 title claims abstract description 27
- 208000007882 Gastritis Diseases 0.000 title claims abstract description 16
- 208000000718 duodenal ulcer Diseases 0.000 title claims abstract description 11
- 229940079593 drug Drugs 0.000 title description 6
- 238000000034 method Methods 0.000 title description 3
- 230000008569 process Effects 0.000 title description 2
- 208000007107 Stomach Ulcer Diseases 0.000 title 1
- 230000002496 gastric effect Effects 0.000 title 1
- 201000005917 gastric ulcer Diseases 0.000 title 1
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 9
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 9
- 230000001954 sterilising effect Effects 0.000 claims abstract description 9
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 9
- 238000002360 preparation method Methods 0.000 claims abstract description 8
- 239000002552 dosage form Substances 0.000 claims abstract description 6
- 239000000843 powder Substances 0.000 claims abstract description 6
- 239000002994 raw material Substances 0.000 claims abstract description 5
- 210000002784 stomach Anatomy 0.000 claims description 13
- 239000012535 impurity Substances 0.000 claims description 9
- 241000218176 Corydalis Species 0.000 claims description 8
- 238000005303 weighing Methods 0.000 claims description 4
- 241000180579 Arca Species 0.000 claims description 3
- 241000238370 Sepia Species 0.000 claims description 3
- 201000003639 autosomal recessive cerebellar ataxia Diseases 0.000 claims description 3
- 238000001354 calcination Methods 0.000 claims description 3
- 239000006071 cream Substances 0.000 claims description 3
- 238000002481 ethanol extraction Methods 0.000 claims description 3
- 235000013372 meat Nutrition 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 9
- 230000008901 benefit Effects 0.000 abstract description 2
- 241000237528 Arcidae Species 0.000 abstract 1
- 241001313857 Bletilla striata Species 0.000 abstract 1
- 241000099774 Cuscuta salina Species 0.000 abstract 1
- 241000219061 Rheum Species 0.000 abstract 1
- 235000009411 Rheum rhabarbarum Nutrition 0.000 abstract 1
- IYGYMKDQCDOMRE-UHFFFAOYSA-N d-Bicucullin Natural products CN1CCC2=CC=3OCOC=3C=C2C1C1OC(=O)C2=C1C=CC1=C2OCO1 IYGYMKDQCDOMRE-UHFFFAOYSA-N 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 13
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 13
- 208000025865 Ulcer Diseases 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 231100000397 ulcer Toxicity 0.000 description 5
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 3
- 239000002775 capsule Substances 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 241000411851 herbal medicine Species 0.000 description 3
- 229940069428 antacid Drugs 0.000 description 2
- 239000003159 antacid agent Substances 0.000 description 2
- 230000001458 anti-acid effect Effects 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000001131 transforming effect Effects 0.000 description 2
- 208000019838 Blood disease Diseases 0.000 description 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000000812 cholinergic antagonist Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 210000001198 duodenum Anatomy 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000001156 gastric mucosa Anatomy 0.000 description 1
- 230000007661 gastrointestinal function Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000014951 hematologic disease Diseases 0.000 description 1
- 208000018706 hematopoietic system disease Diseases 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000002048 spasmolytic effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention provides medicine with the advantages of complete function, good therapeutic effect, high cure rate, long medicine effect and no toxin side effect for treating gastritis and duodenal ulcer and a preparation method thereof. The medicine is uses notoginseng, golden thread, tuber of hyacinth bletilla, adlumidin, rhubarb, ark shell and cuttlebone as raw materials for preparing medicinal powder by mixing proportionally, and various dosage forms are prepared by sterilization for 30 minutes at high temperature of 110 DGE C.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of gastritis, stomach, duodenal ulcer, is that raw material is through processing, be refined into Chinese patent medicine with pure Chinese herbal medicine specifically.The invention still further relates to the preparation method of this medicine.
Background technology
For a long time, the harm people's that gastritis, stomach, duodenal ulcer are serious health, this type of disease sickness rate is high and be distributed among the crowd widely.
At present, various to this type of treatment of diseases medicament categories both at home and abroad, its treatment characteristic has nothing in common with each other, but real evident in efficacy and the treating both the principal and secondary aspects of a disease person is very few.As present clinical quite a few medicine that is used for the treatment of, only with single mechanism of action control and treatment disease: antacid class medicine only reaches the purpose of pain relieving and relief of symptoms with the antacid effect; Spasmolytic class medicine only reaches the purpose of pain relieving and relief of symptoms with spasmolysis.And all can not promote wound healing, reconcile gastrointestinal function.
Summary of the invention
The object of the present invention is to provide that a kind of function is complete, good effect, cure rate height, hold the Chinese patent medicine of the treatment gastritis of imitating long and nontoxic, side effect, stomach, duodenal ulcer.
Another object of the present invention provides the preparation method of the medicine of this gastritis, stomach, duodenal ulcer.
Solution of the present invention is based on motherland's Chinese medicine, by the selected all medicines of " interior warp " theoretical " five ZANG-organs and six FU-organs all obtaining QI from the stomach " " the strongly fragrant people's disease of sending out of wood is taken care and pain in gastral cavilty ", general character according to multiple disease is deliberated repeatedly, meticulous effect, make product of the present invention, its drug effect reaches fully gives inner feelings at the beginning of the phase solution, be blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain, antacid convergence, the healing ulcer surface, repair gastric mucosa, and the pathogenic heat of more clearing up and discharging, ascending healthy energy, help transporting and transforming function of the spleen and stomach, auxiliary effect such as dispersing the stagnated live-QI to relieve the stagnation of QI.
Medicine of the present invention is made by following component: (consumption is a weight portion)
Radix Notoginseng 8-28 Rhizoma Coptidis 4-25 Pseudobulbus Bletillae (Rhizoma Bletillae) 10-40 Rhizoma Corydalis 15-50
Radix Et Rhizoma Rhei 8-45 Concha Arcae 15-30 Endoconcha Sepiae 8-25
The optimum weight of medicine of the present invention (part) proportioning is:
Radix Notoginseng 11 Rhizoma Coptidis 8.5 Pseudobulbus Bletillae (Rhizoma Bletillae) 35 Rhizoma Corydalis 29
Radix Et Rhizoma Rhei 14.5 Concha Arcaes 20.4 Endoconcha Sepiaes 17
Above-mentioned each component is made medicine production method of the present invention is:
1, get Radix Notoginseng, Rhizoma Coptidis, Rhizoma Corydalis, Radix Et Rhizoma Rhei earlier and eliminate impurity after the weighing respectively, use ethanol extraction, remove residue, receive cream, oven dry, it is standby to be crushed to 120 orders;
2, get the Pseudobulbus Bletillae (Rhizoma Bletillae) dry product and remove most impurity, be crushed to 120 orders after high-temperature sterilization standby;
3, get Concha Arcae and clean with clear water, eliminate residual meat and silt, it is standby to be crushed to 80 orders down after the calcining through 500-1000 ℃ of high temperature;
4, get Endoconcha Sepiae clean to remove impurity and be crushed to 120 orders after high-temperature sterilization standby;
5, above-mentioned powder is mixed and made into powder by proportioning, made various dosage forms behind the sterilization in 30 minutes through 110 ℃ of high temperature.
The present invention has following advantage through clinical use:
1, the selected multiple pure Chinese herbal medicine of the present invention, each component meet pharmaceutical control law regulation, utilize comprehensive function treatment gastritis, stomach, the duodenum illness of various Chinese herbal medicine, do not contain any chemical constituent, and be nontoxic and do not have any untoward reaction to human body.
2, the present invention need not to decoct, and can be made into various dosage forms (as making the capsule taking convenience) after the modernization process preparation method is extracted, and each dosage form all meets national drug health legislation regulation.
3, mechanism is original, good because the present invention cures the disease, so drug effect is long, and good effect, cure rate height, the extensive and treating both the principal and secondary aspects of a disease of indication.
4, medicine of the present invention has and regulates the flow of vital energy, and treating blood disorders helps the effect of transporting and transforming function of the spleen and stomach, to the also low dose of medication of prevention and health care of healthy elder crowd, both can strengthen digestive function, appetite stimulator, and the generation of preventable disease again really is " ill curing the disease, a no treating diseases and making health-care ".
The present invention's 300 routine clinical application experiments have fully proved above-mentioned superiority:
Select 150 gastritis (various) patient; 150 of stomach, duodenal ulcer patients, age 10-75 year, women 72 people among the gastritis sufferer, male 78 people; Women 63 people among the ulcer patient, male 87 people.
Method of administration: with capsule preparations oral administration of the present invention, every day, three each 1-2 grains serve on 7 days, then each 1 of every day three times, serve on 23 days, were a course of treatment with 30 days.
With capsule preparations of the present invention through a clinical total effective rate 83% of course of therapy gastritis group patient; Ulcer group patient is clinical always 89%.Alternative gastritis group model case 30 people (male 21 people, women 9 people); Ulcer group 30 people (male 19 people, women 11 people) carry out taking medicine of two courses of treatment, carry out after the drug withdrawal following up a case by regular visits in 3 years, and wherein gastritis group 18 people (male 11 people, women 7 people) did not have recurrence in 3 years, were considered as recovery from illness, and 8 people's disease cycle frequencies descend, the morbidity intensity decreases; Ulcer group 14 people (male 10 people, women 4 people) did not have recurrence in 3 years, were considered as recovery from illness, and 14 people's disease cycles descend, the morbidity intensity decreases.
The specific embodiment
Embodiment:
Take by weighing raw material (kilogram) by following proportioning
Radix Notoginseng 12.5 Rhizoma Coptidis 8 Pseudobulbus Bletillae (Rhizoma Bletillae) 33.5 Rhizoma Corydalis 28
Radix Et Rhizoma Rhei 17 Concha Arcaes 22 Endoconcha Sepiaes 19
Production method is as follows:
Get Radix Notoginseng, Rhizoma Coptidis, Rhizoma Corydalis, Rhizoma Coptidis and eliminate impurity after the weighing respectively and remove residue, receive cream with ethanol extraction, oven dry, it is standby to be crushed to 120 orders; High-temperature sterilization is standby after getting the Pseudobulbus Bletillae (Rhizoma Bletillae) dry product and removing impurity and be crushed to 120 orders; Get Concha Arcae and clean with clear water, eliminate residual meat and silt, it is standby to be crushed to 80 orders down after the calcining through 700 ℃ of high temperature; Get Endoconcha Sepiae clean to remove impurity and be crushed to 120 orders after high-temperature sterilization standby.Above-mentioned several fine powder components are mixed in proportion the back 110 ℃ of following constant temperature 30 minutes, and then were cooled to 105 ℃ of constant temperature 10 minutes, reduce to again and make various dosage forms after 100 ℃ of constant temperature were sterilized in 10 minutes.
Claims (3)
1, a kind of medicine for the treatment of gastritis, stomach, duodenal ulcer is characterized in that it is the medicament of being made by the following weight proportion raw material
Radix Notoginseng 8-28 Rhizoma Coptidis 4-25 Pseudobulbus Bletillae (Rhizoma Bletillae) 10-40 Rhizoma Corydalis 15-50
Radix Et Rhizoma Rhei 8-45 Concha Arcae 15-30 Endoconcha Sepiae 8-25.
2, the medicine of treatment gastritis according to claim 1, stomach, duodenal ulcer, wherein the weight proportion of each raw material is
Radix Notoginseng 11 Rhizoma Coptidis 8.5 Pseudobulbus Bletillae (Rhizoma Bletillae) 35 Rhizoma Corydalis 29
Radix Et Rhizoma Rhei 14.5 Concha Arcaes 20.4 Endoconcha Sepiaes 17.
3, the preparation method of the medicine of the described treatment gastritis of claim 2, stomach, duodenal ulcer is characterized in that getting earlier Radix Notoginseng, Rhizoma Coptidis, Rhizoma Corydalis, Radix Et Rhizoma Rhei and eliminates impurity after the weighing respectively, uses ethanol extraction, remove residue, receive cream, oven dry, it is standby to be crushed to 120 orders; Get the Pseudobulbus Bletillae (Rhizoma Bletillae) dry product and remove most impurity, be crushed to 120 orders after high-temperature sterilization standby; Get Concha Arcae and clean with clear water, eliminate residual meat and silt, it is standby to be crushed to 80 orders down after the calcining through 500-1000 ℃ of high temperature; Get Endoconcha Sepiae clean to remove impurity and be crushed to 120 orders after high-temperature sterilization standby; Above-mentioned powder is mixed and made into powder by proportioning, made various dosage forms behind the sterilization in 30 minutes through 110 ℃ of high temperature.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021380082A CN1177606C (en) | 2002-07-24 | 2002-07-24 | Medicine for treating gastritis and gastric or duodenal ulcer and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021380082A CN1177606C (en) | 2002-07-24 | 2002-07-24 | Medicine for treating gastritis and gastric or duodenal ulcer and its preparing process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1390600A CN1390600A (en) | 2003-01-15 |
| CN1177606C true CN1177606C (en) | 2004-12-01 |
Family
ID=4749231
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB021380082A Expired - Fee Related CN1177606C (en) | 2002-07-24 | 2002-07-24 | Medicine for treating gastritis and gastric or duodenal ulcer and its preparing process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1177606C (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1330355C (en) * | 2005-06-02 | 2007-08-08 | 陈贤柱 | Chinese medicinal composition for treating ulcer |
| CN105288352A (en) * | 2015-10-23 | 2016-02-03 | 彭树林 | Medicine for treating gastric and duodenal ulcer and preparation technology |
| CN108310296A (en) * | 2018-04-23 | 2018-07-24 | 党东 | A kind of Solid oral pharmaceutical for treating stomach trouble |
| CN110038088A (en) * | 2019-05-10 | 2019-07-23 | 边稳利 | A kind of Traditional Chinese medicine liniment and preparation method thereof for treating gastric ulcer |
-
2002
- 2002-07-24 CN CNB021380082A patent/CN1177606C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1390600A (en) | 2003-01-15 |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20041201 Termination date: 20150724 |
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| EXPY | Termination of patent right or utility model |