CN117622876A - Device for guaranteeing uniform suspension mixing and no damage conveying - Google Patents

Abstract

The invention relates to the field of medicine production, and discloses a device for guaranteeing uniform and non-destructive transportation of suspension, which comprises a lifting platform, a shaking table, a control cabinet and a suspension bracket; the lifting platform comprises a platform upper layer, a platform lower layer and an internal lifting mechanism, wherein the platform lower layer is of a hollow structure, and the platform upper layer is lifted under the action of the internal lifting mechanism to leave the platform lower layer or descend to be nested in the platform lower layer; the shaking table is arranged on the upper layer of the platform; the control cabinet is provided with a power socket, an ascending button and a descending button; the suspension bracket comprises a vertical rod and a cross rod at the top end of the vertical rod. The lifting platform is matched with the shaking table for use, so that when the suspension with active substances such as cells is conveyed, the mixing effect is fully ensured, the split charging uniformity is improved, the shaking table is lifted by the lifting platform, the liquid is conveyed by means of gravitational potential energy, and the loss of the active substances such as cells caused by foam generated by shaking by external force and extrusion of the peristaltic pump is avoided.

Description

A device that ensures the suspension is mixed and transported without damage

Technical field

The invention relates to the field of pharmaceutical production, and specifically to a device that ensures uniform mixing and non-destructive delivery of suspension.

Background technique

The containers currently used in pharmaceutical production mainly include plastic or stainless steel containers and disposable bags, and silicone pipelines are used to transport liquids. When using plastic or stainless steel containers to store and transport suspensions, compressed air needs to be used as the power source, and external shaking is required to ensure uniform dispersion. However, violent shaking will produce a large amount of foam, which can easily cause damage to cells and other active substances in the suspension. harm. Use disposable bags to store the suspension and use a shaker to mix when transporting. Because disposable bags cannot use compressed air as a power source, a peristaltic pump must be used as a power source; however, the extrusion of a peristaltic pump can easily cause the loss of cells and other active substances in the suspension.

Contents of the invention

In order to overcome the shortcomings of the existing technology, the present invention provides a device that ensures uniform mixing and lossless transportation of the suspension. The technical solution is as follows:

A device that ensures uniform mixing and lossless transportation of suspension, which includes a lifting platform, a shaker, a control cabinet and a suspension bracket; the lifting platform includes an upper platform, a lower platform and an internal lifting mechanism. The lower platform is a hollow structure, and the platform The upper layer is lifted by the internal lifting mechanism to leave the lower layer of the platform or descend to be nested in the lower layer of the platform. There is a height fixing mechanism between the upper layer of the platform and the lower layer of the platform to fix the upper layer of the platform at a corresponding height position; the shaker is placed on The upper layer of the platform; the control cabinet is installed on the side of the lower layer of the platform. The control cabinet is equipped with a power socket, an ascending button and a descending button. The control cabinet is electrically connected to the shaker and the internal lifting mechanism respectively; the suspension bracket is installed on the lower layer of the platform. The vertical bar on the side and the cross bar on the top are provided with hooks for hanging the liquid storage bag at the end of the cross bar.

Further, the internal lifting mechanism includes a scissor frame, a hydraulic cylinder, a hydraulic pump and a motor. The upper end of the scissor frame is hinged to the upper layer of the platform, and the lower end is hinged to the bottom of the lower platform. The hydraulic cylinder is installed at the lower part of the scissor frame and passes through the piston rod. It is hinged with the middle part of the scissor frame, the hydraulic pump is connected to the hydraulic cylinder through the oil pipe, and the motor drives the hydraulic pump.

Further, the vertical rod of the suspension bracket includes an upper rod and a lower rod. The lower rod is a hollow structure, and the upper rod is inserted into the lower rod; the upper rod and the lower rod are provided with corresponding bracket pin holes, and the upper rod can be fixed by matching pins. at the corresponding height position.

Further, the contact surface between the upper layer of the platform and the lower layer of the platform is provided with fumigation-resistant silicone sealing strips; guardrails are provided around the upper layer of the platform; handrails are provided on the upper part of the lower layer of the platform, and the control cabinet is installed on one side of the handrail.

Further, the height fixing mechanism includes platform latch holes and matching latch pins provided correspondingly on the upper layer of the platform and the lower layer of the platform.

Furthermore, the lower layer of the platform is equipped with swivel casters.

Furthermore, the swivel casters are oil-free casters that are resistant to fumigation and disinfectants.

Furthermore, the control cabinet is equipped with an emergency stop button.

Furthermore, the outer surfaces of the upper platform, lower platform, control cabinet, suspension bracket and shaker are all made of stainless steel.

Further, the shaker adopts a shaker or stirrer that mixes by shaking.

The basic working principle of the present invention is as follows:

When in use, control the descent button to lower the lifting platform to the lowest level, place the suspension on the shaker of the lifting platform, connect the shaker to the power socket of the control cabinet and run the shaker. Control the rising button to raise the lifting platform to the highest point and insert the latch, so that the liquid is mixed at the highest point and discharged from the liquid outlet pipe of the liquid storage bag by relying on gravity potential energy. When there is a small amount of suspension remaining in the liquid storage bag that cannot be emptied, hang the liquid storage bag on the hook at the end of the horizontal bar of the suspension bracket, insert the vertical rod of the suspension bracket from the upper rod into the lower rod, and use the matching latch to secure it. The upper rod is fixed at the corresponding height position until the liquid in the bag is fully drained.

Compared with the existing technology, the present invention mainly has the following beneficial technical effects:

1. The present invention uses a lifting platform in conjunction with a shaker. When transporting a suspension containing cells and other active substances, it not only fully ensures the mixing effect and improves the uniformity of packaging, but also through the lifting platform Elevate the shaking table and rely on gravity potential energy to transport the liquid, thus avoiding the loss of cells and other active substances caused by foam generated by external shaking and extrusion of the peristaltic pump.

2. The upper platform of the lifting platform of the present invention is driven up and down by the scissor-type hydraulic lifting structure, which is simple to operate, flexible and efficient. The motor drives the hydraulic pump to work, and the hydraulic pump applies mechanical energy to the scissor frame through the hydraulic cylinder, and the scissor frame drives the upper layer of the platform to move up and down. The rise and fall of the upper layer of the platform is controlled by the forward and reverse rotation of the motor. When the upper level of the platform is lowered to the lowest level, most of the upper level of the platform is nested within the lower structure of the platform; when the upper level of the platform rises, the scissor frame slowly raises the upper level to the highest position, at which time the latch needs to be inserted; the upper level of the platform can be raised as needed Or drop to any location.

3. Compact structure and high automation level.

4. It can be easily moved to different working places through the universal casters.

Description of drawings

Figure 1 is a schematic diagram of the three-dimensional structure of the present invention;

Figure 2 is a schematic diagram of the internal lifting mechanism of the lifting platform of the present invention;

Figure 3 is a schematic front view of the present invention;

Figure 4 is a schematic left view of the present invention;

Figure 5 is a schematic top view of the present invention;

In the picture: 1-shaking table, 2-hook, 3-cross bar, 4-upper platform, 5-platform latch hole, 6-bracket latch hole, 7-lower platform, 8-vertical rod, 8.1-upper rod, 8.2-Lower rod, 9-Silicone sealing strip, 10-Swivel casters, 11-Up button, 12-Handrail, 13-Power socket, 14-Down button, 15-Guardrail, 16-Scissor stand, 17-Hydraulic cylinder , 18-hydraulic pump, 19-motor, 20-oil pipe.

Detailed ways

The present invention will be described in detail below with reference to the embodiments and drawings.

Example 1

See Figure 1, Figure 2, Figure 3, Figure 4 and Figure 5. A device that ensures uniform mixing and lossless transportation of suspension, which includes a lifting platform, a shaker 1, a control cabinet and a suspension bracket; the lifting platform includes an upper platform 4, a lower platform 7 and an internal lifting mechanism. The lower platform 7 is a hollow structure , the upper layer 4 of the platform rises to leave the lower layer 7 of the platform or descends to be nested in the lower layer 7 of the platform due to the action of the internal lifting mechanism. There is a height fixing mechanism between the upper layer 4 of the platform and the lower layer 7 of the platform to fix the upper layer 4 of the platform at the corresponding height position. ; The shaker 1 is placed on the upper level 4 of the platform; the control cabinet is installed on the side of the lower level 7 of the platform. The control cabinet is equipped with a power socket 13, an up button 11 and a down button 14. The control cabinet is electrically connected to the shaker 1 and the internal lifting mechanism respectively. Connection; the suspension bracket includes a vertical bar 8 installed on the side of the lower platform 7 and a cross bar 3 on its top. The end of the cross bar 3 is provided with a hook 2 for hanging the liquid storage bag.

Example 2

See Figure 1, Figure 2, Figure 3, Figure 4 and Figure 5. A device that ensures uniform mixing and lossless transportation of suspension. Based on the technical solution recorded in Embodiment 1, the internal lifting mechanism includes a scissor frame 16, a hydraulic cylinder 17, a hydraulic pump 18 and a motor 19. The scissor frame 16 The upper end is hinged with the upper layer 4 of the platform, and the lower end is hinged with the bottom of the lower layer 7 of the platform. The hydraulic cylinder 17 is installed at the lower part of the scissor frame 16 and is hinged with the middle part of the scissor frame 16 through the piston rod. The hydraulic pump 18 is connected to the hydraulic cylinder 17 and the motor 19 through the oil pipe 20 Drive hydraulic pump 18.

Example 3

See Figure 1, Figure 2, Figure 3, Figure 4 and Figure 5. A device that ensures uniform mixing and lossless transportation of suspension. Based on the technical solution recorded in Embodiment 1, the vertical rod 8 of the suspension bracket includes an upper rod 8.1 and a lower rod 8.2. The lower rod 8.2 is a hollow structure, and the upper rod 8.1 Insert the lower rod 8.2; the upper rod 8.1 and the lower rod 8.2 are provided with corresponding bracket pin holes 6, and the upper rod 8.1 can be fixed at the corresponding height position through matching pins.

Example 4

See Figure 1, Figure 2, Figure 3, Figure 4 and Figure 5. A device that ensures uniform mixing and non-destructive transportation of the suspension. Based on the technical solution recorded in Embodiment 1, the contact surface between the upper platform layer 4 and the lower platform layer 7 is provided with a fumigation-resistant silicone sealing strip 9 to reduce cleaning dead corners; Guardrails 15 are provided around the upper layer 4 of the platform to prevent slipping; handrails 12 are provided on the upper part of the lower layer 7 of the platform, and the control cabinet is installed on one side of the handrail 12.

Example 5

See Figure 1, Figure 2, Figure 3, Figure 4 and Figure 5. A device to ensure uniform mixing and non-destructive transportation of suspension. Based on the technical solution recorded in Embodiment 1, the height fixing mechanism includes platform pin holes 5 and matching pins provided correspondingly on the upper platform layer 4 and the lower platform layer 7 .

Example 6

See Figure 1, Figure 2, Figure 3, Figure 4 and Figure 5. A device that ensures uniform mixing and lossless transportation of suspension. Based on the technical solution recorded in Embodiment 1, the lower layer 7 of the platform is provided with swivel casters 10 to facilitate flexible movement; the swivel casters 10 are preferably fumigation-resistant and resistant to Disinfectant-free casters do not produce shedding and do not affect the environment of the clean area.

Example 7

See Figure 1, Figure 2, Figure 3, Figure 4 and Figure 5. A device that ensures uniform mixing and non-destructive transportation of suspension. Based on the technical solution recorded in Embodiment 1, the control cabinet is equipped with an emergency stop button so that the equipment can stop working at any time when an abnormality occurs.

Example 8

See Figure 1, Figure 2, Figure 3, Figure 4 and Figure 5. A device that ensures uniform mixing and non-destructive transportation of suspension. Based on the technical solution recorded in Embodiment 1, the outer surfaces of the upper platform 4, lower platform 7, control cabinet, suspension bracket and shaker 1 are all made of stainless steel. Easy to wipe without dead spots; Shaker 1 uses a shaker or stirrer that mixes by oscillation.

The division of the above embodiments is relative, and the technical solutions between the embodiments can be flexibly combined according to actual conditions.

In order to enable those skilled in the art to better understand the present invention, its specific working process is briefly introduced as follows:

First, connect the shaker 1 to the power socket 13 of the device, and operate the control cabinet lowering button 14 to lower the upper platform 4 of the lifting platform to the lowest point. Transfer the disposable bag containing the suspension to the shaker 1 on the lifting platform, start the shaker 1, and continue to mix the suspension in the disposable bag.

Operate the rising button 11 of the control cabinet to slowly raise the upper platform 4 of the lifting platform. After rising to the highest position, insert the latch into the latch hole 5 of the platform; the suspension in the disposable bag remains mixed under the mixing of the shaker 1 state, the suspension in the bag is discharged by gravity potential energy. When a small amount of liquid remains in the bag, first remove the latch in the platform latch hole 5, and operate the control cabinet lowering button 14 to lower the platform upper layer 4 of the lifting platform to the lowest point. Remove the disposable bag, hang the end of the disposable bag at the end hook 2 of the suspension bracket crossbar 3, make the liquid outlet end of the disposable bag facing downward, and move the upper rod 8.1 from the lower rod 8.2 to After lifting it to a suitable height, insert a latch into the latch hole 6 of the bracket to fix it, so that the liquid can continue to be discharged by gravity.

Claims (10)

1. A device that ensures uniform mixing and lossless transportation of suspension, characterized in that it includes a lifting platform, a shaker, a control cabinet and a suspension bracket; the lifting platform includes an upper platform, a lower platform and an internal lifting mechanism, and the lower platform It is a hollow structure, and the upper layer of the platform rises to leave the lower layer of the platform or descends to be nested in the lower layer of the platform due to the action of the internal lifting mechanism. There is a height fixing mechanism between the upper layer of the platform and the lower layer of the platform to fix the upper layer of the platform at a corresponding height position; The shaker is placed on the upper level of the platform; the control cabinet is installed on the side of the lower level of the platform. The control cabinet is equipped with a power socket, an up button and a down button. The control cabinet is electrically connected to the shaker and the internal lifting mechanism respectively; the suspension bracket It includes a vertical bar installed on the lower side of the platform and a cross bar at the top. The end of the cross bar is provided with a hook for hanging the liquid storage bag. 2. A device for ensuring uniform mixing and lossless transportation of suspension according to claim 1, characterized in that the internal lifting mechanism includes a scissor frame, a hydraulic cylinder, a hydraulic pump and a motor, and the upper end of the scissor frame It is hinged with the upper layer of the platform, and the lower end is hinged with the bottom of the lower platform. The hydraulic cylinder is installed at the lower part of the scissor frame and is hinged with the middle part of the scissor frame through the piston rod. The hydraulic pump is connected to the hydraulic cylinder through the oil pipe, and the motor drives the hydraulic pump. 3. A device for ensuring uniform mixing and non-destructive transportation of suspension according to claim 1, characterized in that the vertical rod of the suspension bracket includes an upper rod and a lower rod, the lower rod is a hollow structure, and the upper rod is inserted into The lower pole; the upper pole and the lower pole are equipped with corresponding bracket pin holes, and the upper pole can be fixed at the corresponding height position through matching pins. 4. A device for ensuring uniform mixing and non-destructive transportation of suspension according to claim 1, characterized in that the contact surface between the upper layer of the platform and the lower layer of the platform is provided with a fumigation-resistant silicone sealing strip; the upper layer of the platform is surrounded by There are guardrails; there are handrails on the upper part of the lower platform, and the control cabinet is installed on one side of the handrails. 5. A device for ensuring uniform mixing and lossless transportation of suspension according to claim 1, characterized in that the height fixing mechanism includes platform latch holes and matching latch pins provided correspondingly on the upper layer of the platform and the lower layer of the platform. 6. A device for ensuring uniform mixing and non-destructive transportation of suspension according to claim 1, characterized in that the lower layer of the platform is provided with universal casters. 7. A device for ensuring uniform mixing and non-destructive transportation of suspension according to claim 6, characterized in that the swivel casters are oil-free casters that are resistant to fumigation and disinfectants. 8. A device for ensuring uniform mixing and non-destructive transportation of suspension according to claim 1, characterized in that the control cabinet is provided with an emergency stop button. 9. A device for ensuring uniform mixing and non-destructive transportation of suspension according to claim 1, characterized in that the outer surfaces of the upper platform, lower platform, control cabinet, suspension bracket and shaker are all made of stainless steel. . 10. A device for ensuring uniform mixing and non-destructive transportation of suspension according to claim 1, characterized in that the shaker is a shaker or stirrer that mixes by oscillation.