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CN117338689B - Cosmetics and base compositions for instantly improving skin condition - Google Patents

Cosmetics and base compositions for instantly improving skin condition Download PDF

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Publication number
CN117338689B
CN117338689B CN202311447892.5A CN202311447892A CN117338689B CN 117338689 B CN117338689 B CN 117338689B CN 202311447892 A CN202311447892 A CN 202311447892A CN 117338689 B CN117338689 B CN 117338689B
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extract solution
solution
cosmetic
skin condition
matrix composition
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CN117338689A (en
Inventor
裴运林
孙云起
冼嘉星
聂艳峰
郭朝万
蒲艳
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Guangdong Marubi Biological Technology Co Ltd
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Guangdong Marubi Biological Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • A61K2800/522Antioxidants; Radical scavengers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cosmetics (AREA)

Abstract

本申请涉及化妆品领域,涉及一种即时提升皮肤状态的化妆品、基质组合物。以质量百分比计,基质组合物中各个组分在化妆品中的添加量为:交替单胞菌发酵产物提取物溶液0.1%‑5%;十四烷基氨基丁酰缬氨酰胺基丁酸脲三氟乙酸盐溶液0.1%‑2%;紫檀木提取物溶液0‑10%;欧蓍草提取物溶液0‑6%。上述技术方案中,通过在化妆品中添加上述的基质组合物可以有效地实现化妆品即时提升皮肤状态的作用。进一步地,上述的基质组合物通过搭建交替单胞菌发酵产物提取物溶液、十四烷基氨基丁酰缬氨酰胺基丁酸脲三氟乙酸盐溶液、紫檀木提取物溶液、欧蓍草提取物溶液组成的护肤基质,得到一款可用于多种体系的、可用于全面部的快速淡纹护肤品。The present application relates to the field of cosmetics, and to a cosmetic and matrix composition that can instantly improve the skin condition. In terms of mass percentage, the amount of each component in the matrix composition added to the cosmetics is: 0.1%-5% of the extract solution of the fermentation product of Alteromonas; 0.1%-2% of the tetradecylaminobutyryl valinylamide butyric acid urea trifluoroacetate solution; 0-10% of the red sandalwood extract solution; 0-6% of the yarrow extract solution. In the above technical scheme, by adding the above matrix composition to the cosmetics, the effect of the cosmetics instantly improving the skin condition can be effectively achieved. Furthermore, the above matrix composition is constructed by constructing a skin care matrix composed of the extract solution of the fermentation product of Alteromonas, the tetradecylaminobutyryl valinylamide butyric acid urea trifluoroacetate solution, the red sandalwood extract solution, and the yarrow extract solution, to obtain a quick wrinkle-lightening skin care product that can be used in a variety of systems and can be used for the entire face.

Description

Cosmetic and matrix composition for immediate improvement of skin condition
Technical Field
The application relates to the field of cosmetics, in particular to a cosmetic and matrix composition for immediately improving skin state.
Background
Along with the improvement of the living standard of people, the number of social gathering is also improved remarkably, and people pay more attention to the delicate face, so that the problem of fine lines and wrinkles is certainly one of the most desirable problems of people.
However, the anti-aging cosmetics currently on the market generally need 28-58 days to be effective, but when they temporarily attend important occasions, people rapidly increase their skin conditions including fine lines, skin roughness, luster, etc., so that products having rapid onset of action are also required. Among them, the effect of rapid wrinkle resistance is most important.
Disclosure of Invention
The embodiment of the application aims to provide a cosmetic and matrix composition for immediately improving skin state.
In a first aspect, the present application provides a cosmetic product for immediate improvement of skin condition, the cosmetic product comprising a matrix composition; the matrix composition comprises: alteromonas fermentation product extract solution, tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution, pterocarpus santalinus extract solution, achillea tragacanth extract solution; the matrix composition comprises the following components in percentage by mass: 0.1% -5% of alteromonas fermentation product extract solution; 0.1% -2% of tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution; 0-10% of Pterocarpus extract solution; 0-6% of yarrow extract solution.
In the technical scheme, the matrix composition is added into the cosmetics to effectively realize the effect of the cosmetics on immediately improving the skin state.
Furthermore, the matrix composition can be used for preparing a fast light-line skin care product which can be used for various systems and whole faces by constructing a skin care matrix consisting of an alteromonas fermentation product extract solution, a tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution, a pterocarpus santalinus extract solution and a tragacanth extract solution.
In other embodiments of the present application, the amount of each component in the matrix composition added to the cosmetic in mass percent is: 0.1% -5% of alteromonas fermentation product extract solution; 0.1% -2% of tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution; 5% -10% of pterocarpus santalinus extract solution; 2% -6% of yarrow extract solution.
In other embodiments of the present application, the amount of each component in the matrix composition added to the cosmetic in mass percent is: 3% -5% of alteromonas fermentation product extract solution; 0.5% -2% of tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution; 5% -10% of pterocarpus santalinus extract solution; 2% -6% of yarrow extract solution.
In other embodiments of the application, the alteromonas fermentation product extract solution comprises greater than or equal to 0.5% by mass of the efficacy.
In other embodiments of the present application, the solution of tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate comprises 0.1% or more of the functional material by mass.
In other embodiments of the present application, the pterocarpus santalinus extract solution comprises 2.70% or more of the functional substance by mass.
In other embodiments of the present application, the solution of yarrow extract comprises 0.1% or more by mass of the efficacy product.
In other embodiments of the present application, the cosmetic further comprises, in mass percent: 1% -2% of PEG-40 hydrogenated castor oil; 2% -8% of glycerol; 0.5% -4% of butanediol; dipotassium glycyrrhizinate 0.1% -0.8%; EDTA disodium 0.01% -0.2%; sodium hyaluronate 0.01% -0.1%; carbomer 0.05% -0.25%; 0.01% -0.2% of sclerotium rolfsii; 0.03% -0.15% of aminomethyl propanol solution; octanoyl hydroxamic acid solution 0.2% -1%; 0.1% -1% of polyglycerol-10 myristate solution; the balance being water.
In other embodiments of the application, the octanoyl hydroxamic acid solution comprises: butanediol, octanoyl hydroxamic acid, ethylhexyl, glycerol, 1, 2-hexanediol, and water.
In other embodiments of the present application, the aminomethyl propanol solution comprises: aminomethylpropanol and water.
In other embodiments of the application, the polyglycerin-10 myristate solution comprises: glycerol, diphenyl polydimethylsiloxane, glycerol tris (ethylhexanoate), polyglycerol-10 myristate and water.
In a second aspect, the present application provides a matrix composition for use in a cosmetic product for immediate improvement of skin conditions provided in the first aspect, the matrix composition comprising: alteromonas fermentation product extract solution, tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution, pterocarpus santalinus extract solution, and tragacanth extract solution.
In other embodiments of the application, the matrix composition comprises, in parts by mass: 0.1% -5% of alteromonas fermentation product extract solution; 0.1% -2% of tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution; 0-10% of Pterocarpus extract solution; 0-6% of yarrow extract solution.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present application more apparent, the technical solutions in the embodiments of the present application will be clearly and completely described below, and it is apparent that the described embodiments are some embodiments of the present application, but not all embodiments.
Thus, the following detailed description of the embodiments of the application is not intended to limit the scope of the application, as claimed, but is merely representative of selected embodiments of the application. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.
In order to achieve the effect of rapid wrinkle resistance, the following general categories are adopted:
1. Filling class
The physical filling of wrinkles with silica or silicone elastomers has achieved a rapid wrinkle smoothing effect, typically in the form of emulsions, with the risk of mud pickup and skinning after absorption.
2. Polysaccharides and their use
The macromolecular polysaccharide raw material can rapidly form a film on the surface of skin, and the layer of polysaccharide film can rapidly spread wrinkles to achieve the effect of smoothing the wrinkles, and can also rapidly and perceptively tighten the feel and make the skin smoother. However, the polysaccharide film has poor water resistance and sweat resistance, is incompatible with grease, cannot be applied to an emulsifying system, cannot be matched with other products for use, has obvious tightening sense, cannot be applied in a large area, and is only suitable for an eye essence formula based on the characteristics.
3. Peptides
For example, high concentration of snake venom peptide and other raw materials acting on neurotransmitter targets can paralyze muscles, and can play a role in quickly relaxing muscles as long as the concentration is large enough, so as to achieve a quick anti-wrinkle effect. The disadvantage is that it is generally relatively expensive.
The embodiment of the application provides a cosmetic for immediately improving the skin state, which comprises a matrix composition; the matrix composition comprises: alteromonas fermentation product extract solution, tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution, pterocarpus santalinus extract solution, achillea tragacanth extract solution; the matrix composition comprises the following components in percentage by mass: 0.1% -5% of alteromonas fermentation product extract solution; 0.1% -2% of tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution; 0-10% of Pterocarpus extract solution; 0-6% of yarrow extract solution.
In the technical scheme, the matrix composition is added into the cosmetics to effectively realize the effect of the cosmetics on immediately improving the skin state.
Furthermore, the matrix composition can be used for preparing a fast light-line skin care product which can be used for various systems and whole faces by constructing a skin care matrix consisting of an alteromonas fermentation product extract solution, a tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution, a pterocarpus santalinus extract solution and a tragacanth extract solution.
Furthermore, in the technical scheme, the alteromonas fermentation product extract solution can reduce the generation and migration of neurons and reduce the possibility of generating synaptic connection; decrease clathrin to slow down synaptic vesicle recirculation and neuronal exocytosis, decrease acetylcholine release; reducing neuronal signaling, thereby reducing activation of postsynaptic pathways; reducing acetylcholine receptors to relax muscles in many ways, such as by relaxing activation of postsynaptic pathways. The alteromonas fermentation product extract solution is compounded with the tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution, so that rapid striae lightening can be effectively realized; and is applicable to a full face.
Furthermore, in the technical scheme, the tetradecylamino Ding Xianxie amino amidobutyric urea trifluoroacetate solution can promote the synthesis of self hyaluronic acid in vivo, and can tighten and plump skin at multiple positions. The tetradecylamino Ding Xianxie amino amidobutyric urea trifluoroacetate solution is compounded with the alteromonas fermentation product extract solution, so that rapid striae lightening can be effectively realized; and is applicable to a full face.
Furthermore, in the technical scheme, the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution has strong oxygen radical absorption capacity; the DPPH free radical inhibiting capability is very strong; can inhibit melanin generation; inhibiting elastase and collagenase, thereby improving wrinkles; can lighten skin color; can reduce ultraviolet damage; has anti-saccharification capability.
In some embodiments of the application, the rapid striae lightening can be effectively realized by compounding the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution, the tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution and the alteromonas fermentation product extract solution; and has long-acting anti-aging effect, and can achieve long-acting skin color brightening and long-acting oxidation resistance, thereby realizing instant and long-acting anti-aging.
Furthermore, in the technical scheme, the yarrow (ACHILLEA MILLEFOLIUM) extract solution can influence MC-2R receptor and MOR-1 receptor through adrenocorticotropic hormone and endorphin, so that the differentiation, migration and proliferation of keratinocytes are promoted, the skin blemish is improved, the skin surface is perfected, and the skin is enabled to be light-colored from inside to outside.
In some embodiments of the present application, not only can rapid streaking be effectively achieved by compounding an extract solution of yarrow (ACHILLEA MILLEFOLIUM) with a solution of pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract, a solution of tetradecylamino Ding Xianxie amino butyric acid urea trifluoroacetate, an extract solution of alteromonas fermentation products; and has long-acting anti-aging effect, and can promote the differentiation of keratinocytes for a long time, thereby realizing instant and long-acting anti-aging.
In the above technical scheme, the addition amount of the alteromonas fermentation product extract solution, the tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution, the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution and the milfoil (ACHILLEA MILLEFOLIUM) extract solution in the cosmetics is limited in the above range, so that the effect of rapid graining can be effectively achieved.
Further, in some embodiments of the present application, the individual components of the matrix composition are added to the cosmetic in the following amounts by mass percent: 0.1% -5% of alteromonas fermentation product extract solution; 0.1% -2% of tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution; 5-10% of pterocarpus santalinus extract solution; 2-6% of yarrow extract solution.
In the technical scheme, the addition amount of the alteromonas fermentation product extract solution, the tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution, the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution and the milfoil (ACHILLEA MILLEFOLIUM) extract solution in the cosmetics is limited in the range, so that the effects of rapid graining can be effectively realized, and meanwhile, the cosmetic composition has long-acting anti-aging effect, can achieve long-acting skin color brightening, long-acting antioxidation and long-acting acceleration of keratinocyte differentiation, thereby realizing instant and long-acting anti-aging.
Further, in some embodiments of the present application, the individual components of the matrix composition are added to the cosmetic in the following amounts by mass percent: 3% -5% of alteromonas fermentation product extract solution; 0.5% -2% of tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution; 5-10% of pterocarpus santalinus extract solution; 2-6% of yarrow extract solution.
In the technical scheme, the addition amount of the alteromonas fermentation product extract solution, the tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution, the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution and the milfoil (ACHILLEA MILLEFOLIUM) extract solution in the cosmetic is further limited, so that the effect of rapid wrinkle lightening can be further effectively improved, and meanwhile, the cosmetic has a long-acting anti-aging effect, can achieve the effects of long-acting brightening skin color, long-acting anti-oxidation and long-acting promotion of keratinocyte differentiation, thereby realizing instant and long-acting anti-aging.
It should be noted that the above-mentioned cosmetics may be in various forms commonly used in the art, such as water, milk, cream, etc.
The other components of the cosmetic can be selected from common components of corresponding dosage forms. Such as the usual aqueous phase, oil phase, etc.
Further, illustratively, in some embodiments of the present application, the individual components of the matrix composition are added to the cosmetic in the following amounts by mass percent:
Alteromonas fermentation product extract solution 0.1%, 0.2%, 0.5%, 0.8%, 1%, 1.2%, 1.5%, 1.8%, 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, 5% or a range between any two of the foregoing;
Tetradecylamino Ding Xianxie amino amidobutyric urea trifluoroacetate solution 0.1%, 0.2%, 0.5%, 0.8%, 1%, 1.2%, 1.5%, 1.8%, 2% or a range between any two of the foregoing;
Pterocarpus extract solution 0, 0.1%, 0.5%, 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10% or a range between any two of the foregoing;
The achillea extract solution 0, 0.1%, 0.5%, 1%, 2%, 3%, 4%, 5%, 6% or a range between any two of the foregoing.
Further, in some embodiments of the application, the alteromonas fermentation product extract solution comprises greater than or equal to 0.5% by mass of the efficacy.
The alteromonas fermentation product extract solution described above can be obtained commercially.
Further, in some embodiments of the application, the alteromonas fermentation product extract solution consists of glycerol, water, caprylyl glycol, alteromonas fermentation product extract; wherein the mass percentage of the alteromonas fermentation product extract is more than or equal to 0.5 percent.
Further, in some embodiments of the application, the solution of tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate comprises 0.1% or more of the functional substance by mass.
Further, in some embodiments of the present application, the above-described solution of tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate is commercially available.
Further, in some embodiments of the present application, the above-described solution of tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate consists of tetradecylamino Ding Xianxie amino amidobutyric acid, urea trifluoroacetate, glycerol, water, magnesium chloride; wherein the mass percentage of the tetradecylamino Ding Xianxie amino amido butyric acid is more than or equal to 0.1 percent.
Further, in some embodiments of the present application, the pterocarpus santalinus extract solution comprises 2.70% or more of the functional substance by mass.
Further, in some embodiments of the present application, the pterocarpus santalinus extract solution described above may be obtained commercially.
Further, in some embodiments of the present application, the pterocarpus santalinus extract solution described above is composed of pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract, caprylic/capric triglyceride, dipropylene glycol, PEG-40 hydrogenated castor oil, 1, 3-propanediol, tocopheryl acetate, glycerol, disodium EDTA, water. Wherein the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract is used as an efficacy substance, and the mass percentage of the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract is more than or equal to 2.70%.
Further, in some embodiments of the present application, the solution of yarrow extract includes 0.1% or more by mass of the efficacy product.
Further, in some embodiments of the present application, the above-described solution of an extract of yarrow may be obtained commercially.
Further, in some embodiments of the present application, the above-described solution of an extract of tragacanth consists of water, butylene glycol, 1, 2-pentanediol, xanthan gum, an extract solution of tragacanth (ACHILLEA MILLEFOLIUM); wherein the milfoil (ACHILLEA MILLEFOLIUM) extract is used as the efficacy substance, and the mass percentage of the milfoil is more than or equal to 0.1%.
Further, in some embodiments of the present application, the composition, in mass percent,
The cosmetic further comprises: 1% -2% of PEG-40 hydrogenated castor oil; 2% -8% of glycerol; 0.5% -4% of butanediol; dipotassium glycyrrhizinate 0.1% -0.8%; EDTA disodium 0.01% -0.2%; sodium hyaluronate 0.01% -0.1%; carbomer 0.05% -0.25%; 0.01% -0.2% of sclerotium rolfsii; 0.03% -0.15% of aminomethyl propanol solution; octanoyl hydroxamic acid solution 0.2% -1%; 0.1% -1% of polyglycerol-10 myristate solution; the balance being water.
Further, in some embodiments of the present application, the composition, in mass percent,
The cosmetic further comprises: 1.1% -1.9% of PEG-40 hydrogenated castor oil; 2.1% -7.9% of glycerol; 0.6% -3.9% of butanediol; dipotassium glycyrrhizinate 0.2% -0.7%; EDTA disodium 0.02% -0.19%; sodium hyaluronate 0.02% -0.19%; carbomer 0.06% -0.24%; 0.02% -0.19% of sclerotium rolfsii; 0.04% -0.14% of aminomethyl propanol solution; octanoyl hydroxamic acid solution 0.21% -0.99%; 0.11% -0.99% of polyglycerol-10 myristate solution; the balance being water.
Illustratively, in some embodiments of the present application, the cosmetic further comprises, in mass percent: 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, 1.6%, 1.7%, 1.8%, 1.9% or a range between any two of the foregoing PEG-40 hydrogenated castor oil values;
Glycerol 2.1%, 2.5%, 2.8%, 3.0%, 3.2%, 3.5%, 4.0%, 4.5%, 5.0%, 5.5%, 6.0%, 6.5%, 7.0%, 7.5%, 7.9% or a range between any two of the foregoing;
0.6%, 0.8%, 1%, 1.2%, 1.5%, 2.0%, 2.5%, 3%, 3.5%, 3.9% butanediol or a range between any two of the foregoing values;
Dipotassium glycyrrhizinate 0.2%, 0.3%, 0.4%, 0.5%, 0.6%, 0.7% or a range between any two of the foregoing;
Disodium EDTA 0.02%, 0.03%, 0.05%, 0.08%, 0.1%, 0.12%, 0.15%, 0.18%, 0.19% or ranges between any two of the foregoing;
Sodium hyaluronate 0.02%, 0.05%, 0.08%, 0.1%, 0.12%, 0.13%, 0.15%, 0.18%, 0.19% or a range between any two of the foregoing;
Carbomer 0.06%, 0.08%, 0.1%, 0.12%, 0.15%, 0.18%, 0.19%, 0.2%, 0.21%, 0.22%, 0.23%, 0.24% or a range between any two of the foregoing;
0.02%, 0.05%, 0.08%, 0.1%, 0.12%, 0.15%, 0.16%, 0.18%, 0.19% or a range between any two of the foregoing values;
Aminomethyl propanol solution 0.04%, 0.05%, 0.08%, 0.1%, 0.12%, 0.13%, 0.14% or a range between any two of the preceding values;
Octanoyl hydroxamic acid solutions 0.21%, 0.23%, 0.25%, 0.28%, 0.3%, 0.35%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 0.99%, or ranges between any two of the foregoing;
0.11%, 0.12%, 0.15%, 0.2%, 0.3%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 0.95%, 0.99% or a range between any two of the foregoing values of the polyglycerin-10 myristate solution.
Further, in some embodiments of the application, the octanoyl hydroxamic acid solution comprises: butanediol, octanoyl hydroxamic acid, ethylhexyl, glycerol, 1, 2-hexanediol, and water.
Further, in some embodiments of the application, the aminomethyl propanol solution comprises: aminomethylpropanol and water.
Further, in some embodiments of the application, the polyglycerin-10 myristate solution comprises: glycerol, diphenyl polydimethylsiloxane, glycerol tris (ethylhexanoate), polyglycerol-10 myristate and water.
Some embodiments of the present application provide a matrix composition in a cosmetic product for immediately improving skin condition provided in the first aspect.
Further, in some embodiments of the application, the matrix composition comprises: alteromonas fermentation product extract solution, tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution, pterocarpus santalinus extract solution, and tragacanth extract solution.
Further, in some embodiments of the present application, the matrix composition comprises, in parts by weight: 0.1% -5% of alteromonas fermentation product extract solution; 0.1% -2% of tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution; 0-10% of Pterocarpus extract solution; 0-6% of yarrow extract solution.
The matrix composition is used for preparing a skin care matrix which is composed of alteromonas fermentation product extract solution, tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution, pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution and yarrow (ACHILLEA MILLEFOLIUM) extract solution, so that the skin care product which can be used for various systems and can be used for comprehensive rapid light-line skin care is obtained.
The following examples are set forth to better illustrate the application.
[ Example ]
A cosmetic for improving skin condition in real time is provided, and the formula of the cosmetic is shown in Table 1. Units in table 1: wt.%.
TABLE 1
The cosmetic is prepared according to the following preparation steps:
1. Adding phase A into water phase pot, stirring, heating to 70-90deg.C, and maintaining for 10-30min.
2. Pumping the raw materials into an emulsifying pot, vacuumizing, homogenizing, and maintaining the temperature for 10-30min.
3. Cooling to 60-70deg.C, adding phase B, cooling to 35-50deg.C, adding phase C, D, and stirring for 15min.
The amounts of the individual components in the matrix composition are primarily adjusted in the various examples, with the amounts of the other components being as indicated in the table above.
Example 1
1. Alteromonas fermentation product extract solution: 0.1%
2. Tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution: 0.1%
3. Pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution: 0% of
4. Milfoil (ACHILLEA MILLEFOLIUM) extract solution: 0% of
Wherein the content of the functional substance in the alteromonas fermentation product extract solution is 0.5%;
The content of the functional substance in the tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution is 0.1%;
the content of the functional substance in the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution is 0.28%;
the content of the functional substance in the achillea (ACHILLEA MILLEFOLIUM) extract solution is 0.5%.
Example 2
1. Alteromonas fermentation product extract solution: 1%
2. Tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution: 0.5%
3. Pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution: 0% of
4. Milfoil (ACHILLEA MILLEFOLIUM) extract solution: 0% of
Wherein the content of the functional substance in the alteromonas fermentation product extract solution is 0.5%;
The content of the functional substance in the tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution is 0.1%;
the content of the functional substance in the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution is 0.28%;
the content of the functional substance in the achillea (ACHILLEA MILLEFOLIUM) extract solution is 0.5%.
Example 3
1. Alteromonas fermentation product extract solution: 3%
2. Tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution: 1.5%
3. Pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution: 0% of
4. Milfoil (ACHILLEA MILLEFOLIUM) extract solution: 0% of
Wherein the content of the functional substance in the alteromonas fermentation product extract solution is 0.5%;
The content of the functional substance in the tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution is 0.1%;
the content of the functional substance in the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution is 0.28%;
the content of the functional substance in the achillea (ACHILLEA MILLEFOLIUM) extract solution is 0.5%.
Example 4
1. Alteromonas fermentation product extract solution: 5%
2. Tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution: 2%
3. Pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution: 0% of
4. Milfoil (ACHILLEA MILLEFOLIUM) extract solution: 0% of
Wherein the content of the functional substance in the alteromonas fermentation product extract solution is 0.5%;
The content of the functional substance in the tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution is 0.1%;
the content of the functional substance in the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution is 0.28%;
the content of the functional substance in the achillea (ACHILLEA MILLEFOLIUM) extract solution is 0.5%.
Example 5
1. Alteromonas fermentation product extract solution: 3%
2. Tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution: 1.5%
3. Pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution: 5%
4. Milfoil (ACHILLEA MILLEFOLIUM) extract solution: 2%
Wherein the content of the functional substance in the alteromonas fermentation product extract solution is 0.5%;
The content of the functional substance in the tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution is 0.1%;
the content of the functional substance in the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution is 0.28%;
the content of the functional substance in the achillea (ACHILLEA MILLEFOLIUM) extract solution is 0.5%.
Example 6
1. Alteromonas fermentation product extract solution: 3%
2. Tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution: 1.5%
3. Pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution: 10 percent of
4. Milfoil (ACHILLEA MILLEFOLIUM) extract solution: 3%
Wherein the content of the functional substance in the alteromonas fermentation product extract solution is 0.5%;
The content of the functional substance in the tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution is 0.1%;
the content of the functional substance in the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution is 0.28%;
the content of the functional substance in the achillea (ACHILLEA MILLEFOLIUM) extract solution is 0.5%.
Blank control sample
1. Alteromonas fermentation product extract solution: 0% of
2. Tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution: 0% of
3. Pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution: 0% of
4. Milfoil (ACHILLEA MILLEFOLIUM) extract solution: 0% of
Wherein the content of the functional substance in the alteromonas fermentation product extract solution is 0.5%;
The content of the functional substance in the tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution is 0.1%;
the content of the functional substance in the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution is 0.28%;
the content of the functional substance in the achillea (ACHILLEA MILLEFOLIUM) extract solution is 0.5%.
Comparative sample 1
1. Alteromonas fermentation product extract solution: 0% of
2. Tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution: 1.5%
3. Pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution: 5%
4. Milfoil (ACHILLEA MILLEFOLIUM) extract solution: 2%
Wherein the content of the functional substance in the alteromonas fermentation product extract solution is 0.5%;
The content of the functional substance in the tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution is 0.1%;
the content of the functional substance in the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution is 0.28%;
the content of the functional substance in the achillea (ACHILLEA MILLEFOLIUM) extract solution is 0.5%.
Comparative sample 2
1. Alteromonas fermentation product extract solution: 3%
2. Tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution: 0% of
3. Pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution: 5%
4. Milfoil (ACHILLEA MILLEFOLIUM) extract solution: 2%
Wherein the content of the functional substance in the alteromonas fermentation product extract solution is 0.5%;
The content of the functional substance in the tetradecylamino Ding Xianxie amino amido butyric urea trifluoroacetate solution is 0.1%;
the content of the functional substance in the pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution is 0.28%;
the content of the functional substance in the achillea (ACHILLEA MILLEFOLIUM) extract solution is 0.5%.
[ Experimental example ]
Samples of each example, blank comparative example, and each comparative example were used for the anti-aging efficacy test.
The laboratory is provided with the following relevant safety test data and instructions for evaluation prior to human testing: product safety instructions, product related toxicological test report (multiple skin irritation test or body patch test).
The anti-wrinkle efficacy, the brightening and pore refining effects of the sample are tested, a front-back control test is adopted, a skin test probe is used for collecting the L-value and the ITA-value of facial skin, a three-dimensional image is used for collecting the number/area of under-eye lines and French lines, the number/area/roughness stm and VISIA-CR images, front-back comparison analysis is carried out on data, and the instant effects before and after 20 minutes of use and the long-term effects after 28 days of use of the product are verified.
The test results are shown in tables 2 to 4.
Table 2 pore roughness data
TABLE 3 wrinkle improvement data
TABLE 4 skin brightness data
From the above experimental data, it can be seen that the matrix composition of the present application is applied to cosmetics, and the skin state can be rapidly improved as a whole after 20 minutes using the cosmetics, which is embodied as rough and smoother skin, reduced wrinkles and improved brightness.
Further, as can be seen from the skin brightness data, the brightness enhancement is more obvious as the compounding scheme of example 5 and example 6, and comparative examples 1-4 show that the brightness enhancement in the composition is mainly based on the stripping effect of the yarrow (ACHILLEA MILLEFOLIUM) extract solution, the yarrow (ACHILLEA MILLEFOLIUM) extract solution has the rapid brightness enhancement effect, and the skin brightness can be improved after long-term use.
Further, as can be seen from the skin roughness improvement data and the wrinkle improvement data, the matrix composition of the present application has the effect of rapidly improving pores and reducing wrinkles. Examples 3-6 comparative examples 1-2 show that the concentration of the matrix composition has a significant impact on the performance of the efficacy. Examples 3-4 comparative examples 1-2 and examples 5-6 demonstrate that alteromonas fermentation product extract solutions and tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solutions in combination, at sufficient concentrations, can exhibit very good immediate striae-lightening effects. Examples 3-4 comparative examples 1-2 demonstrate that the combination of alteromonas fermentation product extract solution with tetradecylamino Ding Xianxie amino amidobutyric acid urea trifluoroacetate solution provides an effect of 1+1 > 2 in terms of instant effect. Examples 5-6 comparative examples 3-4 show that the 28-day long-acting light streak performance is significantly improved as the antioxidant effect is enhanced after the addition of the Pterocarpus santalinus (PTEROCARPUS SANTALINUS) wood extract solution. In summary, the compounding scheme as in example 5 is more satisfactory in view of the rapid effect, the long-term effect, and the cost performance.
The embodiments described above are some, but not all embodiments of the application. The detailed description of the embodiments of the application is not intended to limit the scope of the application, as claimed, but is merely representative of selected embodiments of the application. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.

Claims (12)

1.一种即时提升皮肤状态的化妆品,其特征在于,所述化妆品包括基质组合物;所述基质组合物包括:交替单胞菌发酵产物提取物溶液、十四烷基氨基丁酰缬氨酰胺基丁酸脲三氟乙酸盐溶液、紫檀木提取物溶液、欧蓍草提取物溶液;以质量百分比计,所述基质组合物中各个组分在所述化妆品中的添加量为:所述交替单胞菌发酵产物提取物溶液3%-5%;所述十四烷基氨基丁酰缬氨酰胺基丁酸脲三氟乙酸盐溶液0.5%-2%;所述紫檀木提取物溶液0.1%-10%;所述欧蓍草提取物溶液0.1%-6%;使用所述化妆品20min后皮肤状态提升,包括:皮肤粗糙度降低、皱纹减少以及亮度提升。1. A cosmetic for instantly improving skin condition, characterized in that the cosmetic comprises a matrix composition; the matrix composition comprises: an altermonas fermentation product extract solution, a tetradecylaminobutyryl valinamidobutyric acid urea trifluoroacetate solution, a red sandalwood extract solution, and an achilles extract solution; in terms of mass percentage, the addition amount of each component in the matrix composition in the cosmetic is: 3%-5% of the altermonas fermentation product extract solution; 0.5%-2% of the tetradecylaminobutyryl valinamidobutyric acid urea trifluoroacetate solution; 0.1%-10% of the red sandalwood extract solution; 0.1%-6% of the achilles extract solution; after using the cosmetic for 20 minutes, the skin condition is improved, including: reduced skin roughness, reduced wrinkles, and improved brightness. 2.根据权利要求1所述的即时提升皮肤状态的化妆品,其特征在于,包括:2. The cosmetic for instantly improving skin condition according to claim 1, characterized in that it comprises: 以质量百分比计,所述基质组合物中各个组分在所述化妆品中的添加量为:所述交替单胞菌发酵产物提取物溶液3.5%-5%;所述十四烷基氨基丁酰缬氨酰胺基丁酸脲三氟乙酸盐溶液0.8%-2%;所述紫檀木提取物溶液0.5%-10%;所述欧蓍草提取物溶液0.5%-6%。In terms of mass percentage, the added amounts of the various components in the matrix composition in the cosmetics are: 3.5%-5% of the Alteromonas fermentation product extract solution; 0.8%-2% of the tetradecylaminobutyrylvalinamidobutyric acid urea trifluoroacetate solution; 0.5%-10% of the rosewood extract solution; and 0.5%-6% of the yarrow extract solution. 3.根据权利要求1所述的即时提升皮肤状态的化妆品,其特征在于,包括:3. The cosmetic for instantly improving skin condition according to claim 1, characterized in that it comprises: 以质量百分比计,所述基质组合物中各个组分在所述化妆品中的添加量为:所述交替单胞菌发酵产物提取物溶液3%-5%;所述十四烷基氨基丁酰缬氨酰胺基丁酸脲三氟乙酸盐溶液0.5%-2%;所述紫檀木提取物溶液5%-10%;所述欧蓍草提取物溶液2%-6%。In terms of mass percentage, the added amounts of the various components in the matrix composition in the cosmetics are: 3%-5% of the Alteromonas fermentation product extract solution; 0.5%-2% of the tetradecylaminobutyrylvalinamidobutyric acid urea trifluoroacetate solution; 5%-10% of the rosewood extract solution; and 2%-6% of the yarrow extract solution. 4.根据权利要求1-3任一项所述的即时提升皮肤状态的化妆品,其特征在于,4. The cosmetic for instantly improving skin condition according to any one of claims 1 to 3, characterized in that: 所述交替单胞菌发酵产物提取物溶液包括质量百分含量大于等于0.5%的功效物。The Alteromonas fermentation product extract solution comprises a functional substance with a mass percentage content greater than or equal to 0.5%. 5.根据权利要求1-3任一项所述的即时提升皮肤状态的化妆品,其特征在于,5. The cosmetic for instantly improving skin condition according to any one of claims 1 to 3, characterized in that: 所述十四烷基氨基丁酰缬氨酰胺基丁酸脲三氟乙酸盐溶液包括质量百分含量大于等于0.1%的功效物。The tetradecylaminobutyrylvalinamidobutyric acid urea trifluoroacetate solution comprises a weight percentage content of greater than or equal to 0.1% of the efficacy substance. 6.根据权利要求1-3任一项所述的即时提升皮肤状态的化妆品,其特征在于,6. The cosmetic for instantly improving skin condition according to any one of claims 1 to 3, characterized in that: 所述紫檀木提取物溶液包括质量百分含量大于等于2.70%的功效物。The red sandalwood extract solution includes the efficacy substance in a mass percentage content greater than or equal to 2.70%. 7.根据权利要求1-3任一项所述的即时提升皮肤状态的化妆品,其特征在于,7. The cosmetic for instantly improving skin condition according to any one of claims 1 to 3, characterized in that: 所述欧蓍草提取物溶液包括质量百分含量大于等于0.1%的功效物。The yarrow extract solution comprises the efficacy substance in an amount greater than or equal to 0.1% by weight. 8.根据权利要求1所述的即时提升皮肤状态的化妆品,其特征在于,以质量百分比计,8. The cosmetic for instantly improving skin condition according to claim 1, characterized in that, in terms of mass percentage, 所述化妆品还包括:PEG-40 氢化蓖麻油 1%-2%;甘油 2%-8%;丁二醇 0.5%-4%;甘草酸二钾 0.1%-0.8%;EDTA 二钠0.01%-0.2%;透明质酸钠 0.01%-0.1%;卡波姆 0.05%-0.25%;小核菌胶0.01%-0.2%;氨甲基丙醇溶液0.03%-0.15%;辛酰羟肟酸溶液0.2%-1%;聚甘油-10肉豆蔻酸酯溶液 0.1%-1%;余量为水。The cosmetics also include: PEG-40 hydrogenated castor oil 1%-2%; glycerin 2%-8%; butylene glycol 0.5%-4%; dipotassium glycyrrhizinate 0.1%-0.8%; disodium EDTA 0.01%-0.2%; sodium hyaluronate 0.01%-0.1%; carbomer 0.05%-0.25%; sclerotium gum 0.01%-0.2%; aminomethyl propanol solution 0.03%-0.15%; caprylhydroxamic acid solution 0.2%-1%; polyglyceryl-10 myristate solution 0.1%-1%; and the balance is water. 9.根据权利要求8所述的即时提升皮肤状态的化妆品,其特征在于,9. The cosmetic for instantly improving skin condition according to claim 8, characterized in that: 所述辛酰羟肟酸溶液包括:丁二醇、辛酰羟肟酸、乙基己基、甘油、1,2-己二醇、水。The octanoylhydroxamic acid solution comprises: butanediol, octanoylhydroxamic acid, ethylhexyl, glycerol, 1,2-hexanediol and water. 10.根据权利要求8所述的即时提升皮肤状态的化妆品,其特征在于,10. The cosmetic for instantly improving skin condition according to claim 8, characterized in that: 所述氨甲基丙醇溶液包括:氨甲基丙醇、水。The aminomethyl propanol solution comprises: aminomethyl propanol and water. 11.根据权利要求8所述的即时提升皮肤状态的化妆品,其特征在于,11. The cosmetic for instantly improving skin condition according to claim 8, characterized in that: 所述聚甘油-10 肉豆蔻酸酯溶液包括:甘油、二苯基聚二甲基硅氧烷、甘油三(乙基己酸)酯、聚甘油-10 肉豆蔻酸酯、水。The polyglyceryl-10 myristate solution comprises: glycerin, diphenyl dimethicone, glyceryl tri(ethylhexanoate), polyglyceryl-10 myristate and water. 12.一种基质组合物,其特征在于,所述基质组合物为权利要求1-11任一项所述的即时提升皮肤状态的化妆品中的所述基质组合物,所述基质组合物包括:交替单胞菌发酵产物提取物溶液、十四烷基氨基丁酰缬氨酰胺基丁酸脲三氟乙酸盐溶液、紫檀木提取物溶液、欧蓍草提取物溶液。12. A matrix composition, characterized in that the matrix composition is the matrix composition in the cosmetic for instantly improving skin condition according to any one of claims 1 to 11, and the matrix composition comprises: an extract solution of an Alteromonas fermentation product, a tetradecylaminobutyrylvalinamidobutyric acid urea trifluoroacetate solution, a rosewood extract solution, and an yarrow extract solution.
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