CN117099995A - Antioxidant electronic atomized liquid and preparation method thereof - Google Patents
Antioxidant electronic atomized liquid and preparation method thereof Download PDFInfo
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- CN117099995A CN117099995A CN202311135246.5A CN202311135246A CN117099995A CN 117099995 A CN117099995 A CN 117099995A CN 202311135246 A CN202311135246 A CN 202311135246A CN 117099995 A CN117099995 A CN 117099995A
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- antioxidant
- grape seed
- nicotine
- organic acid
- atomized liquid
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- 230000003078 antioxidant effect Effects 0.000 title claims abstract description 128
- 239000003963 antioxidant agent Substances 0.000 title claims abstract description 125
- 239000007788 liquid Substances 0.000 title claims abstract description 105
- 238000002360 preparation method Methods 0.000 title abstract description 24
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 claims abstract description 75
- 229960002715 nicotine Drugs 0.000 claims abstract description 75
- -1 nicotine organic acid salt Chemical class 0.000 claims abstract description 55
- 229940087603 grape seed extract Drugs 0.000 claims abstract description 49
- 235000002532 grape seed extract Nutrition 0.000 claims abstract description 49
- 239000001717 vitis vinifera seed extract Substances 0.000 claims abstract description 49
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 claims abstract description 47
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 36
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 33
- 150000007524 organic acids Chemical class 0.000 claims abstract description 16
- 239000002904 solvent Substances 0.000 claims abstract description 13
- 239000002994 raw material Substances 0.000 claims abstract description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 47
- 229940087559 grape seed Drugs 0.000 claims description 38
- 239000000843 powder Substances 0.000 claims description 34
- 239000000284 extract Substances 0.000 claims description 19
- 238000000605 extraction Methods 0.000 claims description 16
- 235000011187 glycerol Nutrition 0.000 claims description 12
- 108010059892 Cellulase Proteins 0.000 claims description 11
- 229940106157 cellulase Drugs 0.000 claims description 11
- 230000000694 effects Effects 0.000 claims description 11
- 238000001914 filtration Methods 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 11
- JOOXCMJARBKPKM-UHFFFAOYSA-N 4-oxopentanoic acid Chemical compound CC(=O)CCC(O)=O JOOXCMJARBKPKM-UHFFFAOYSA-N 0.000 claims description 10
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 10
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 10
- 238000002156 mixing Methods 0.000 claims description 9
- 238000002791 soaking Methods 0.000 claims description 8
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- 241000219095 Vitis Species 0.000 claims description 6
- 235000009754 Vitis X bourquina Nutrition 0.000 claims description 6
- 235000012333 Vitis X labruscana Nutrition 0.000 claims description 6
- 235000014787 Vitis vinifera Nutrition 0.000 claims description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 6
- 239000005711 Benzoic acid Substances 0.000 claims description 5
- 108090000790 Enzymes Proteins 0.000 claims description 5
- 102000004190 Enzymes Human genes 0.000 claims description 5
- 235000010233 benzoic acid Nutrition 0.000 claims description 5
- 229940088598 enzyme Drugs 0.000 claims description 5
- 239000004310 lactic acid Substances 0.000 claims description 5
- 235000014655 lactic acid Nutrition 0.000 claims description 5
- 229940040102 levulinic acid Drugs 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- UYEMGAFJOZZIFP-UHFFFAOYSA-N 3,5-dihydroxybenzoic acid Chemical compound OC(=O)C1=CC(O)=CC(O)=C1 UYEMGAFJOZZIFP-UHFFFAOYSA-N 0.000 claims description 4
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 claims description 4
- 239000000443 aerosol Substances 0.000 claims description 4
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 4
- 238000004108 freeze drying Methods 0.000 claims description 4
- 238000007873 sieving Methods 0.000 claims description 4
- 238000003809 water extraction Methods 0.000 claims description 4
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims description 2
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims description 2
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 2
- 235000011054 acetic acid Nutrition 0.000 claims description 2
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 2
- 235000015165 citric acid Nutrition 0.000 claims description 2
- 239000001630 malic acid Substances 0.000 claims description 2
- 235000011090 malic acid Nutrition 0.000 claims description 2
- 235000019260 propionic acid Nutrition 0.000 claims description 2
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 claims description 2
- 239000011975 tartaric acid Substances 0.000 claims description 2
- 235000002906 tartaric acid Nutrition 0.000 claims description 2
- 235000013305 food Nutrition 0.000 claims 3
- 239000007921 spray Substances 0.000 claims 1
- 230000003064 anti-oxidating effect Effects 0.000 abstract description 11
- 230000002035 prolonged effect Effects 0.000 abstract description 3
- 235000006708 antioxidants Nutrition 0.000 description 101
- 230000000052 comparative effect Effects 0.000 description 31
- 238000011056 performance test Methods 0.000 description 14
- 239000000796 flavoring agent Substances 0.000 description 10
- 235000019640 taste Nutrition 0.000 description 10
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 8
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 8
- 230000003647 oxidation Effects 0.000 description 8
- 238000007254 oxidation reaction Methods 0.000 description 8
- 238000000889 atomisation Methods 0.000 description 7
- 238000002474 experimental method Methods 0.000 description 6
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 description 6
- 239000000126 substance Substances 0.000 description 5
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 4
- 229930003268 Vitamin C Natural products 0.000 description 4
- 229930003427 Vitamin E Natural products 0.000 description 4
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 4
- 235000019154 vitamin C Nutrition 0.000 description 4
- 239000011718 vitamin C Substances 0.000 description 4
- 235000019165 vitamin E Nutrition 0.000 description 4
- 229940046009 vitamin E Drugs 0.000 description 4
- 239000011709 vitamin E Substances 0.000 description 4
- 108010024636 Glutathione Proteins 0.000 description 3
- CWEZAWNPTYBADX-UHFFFAOYSA-N Procyanidin Natural products OC1C(OC2C(O)C(Oc3c2c(O)cc(O)c3C4C(O)C(Oc5cc(O)cc(O)c45)c6ccc(O)c(O)c6)c7ccc(O)c(O)c7)c8c(O)cc(O)cc8OC1c9ccc(O)c(O)c9 CWEZAWNPTYBADX-UHFFFAOYSA-N 0.000 description 3
- 150000001765 catechin Chemical class 0.000 description 3
- ADRVNXBAWSRFAJ-UHFFFAOYSA-N catechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3ccc(O)c(O)c3 ADRVNXBAWSRFAJ-UHFFFAOYSA-N 0.000 description 3
- 235000005487 catechin Nutrition 0.000 description 3
- 210000002421 cell wall Anatomy 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- 229960003180 glutathione Drugs 0.000 description 3
- 235000003969 glutathione Nutrition 0.000 description 3
- 230000007062 hydrolysis Effects 0.000 description 3
- 238000006460 hydrolysis reaction Methods 0.000 description 3
- 239000012535 impurity Substances 0.000 description 3
- 150000008442 polyphenolic compounds Chemical class 0.000 description 3
- 235000013824 polyphenols Nutrition 0.000 description 3
- 229920002414 procyanidin Polymers 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 235000016623 Fragaria vesca Nutrition 0.000 description 2
- 240000009088 Fragaria x ananassa Species 0.000 description 2
- 235000011363 Fragaria x ananassa Nutrition 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 206010013954 Dysphoria Diseases 0.000 description 1
- 101001018064 Homo sapiens Lysosomal-trafficking regulator Proteins 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 208000006083 Hypokinesia Diseases 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 102100033472 Lysosomal-trafficking regulator Human genes 0.000 description 1
- 244000038561 Modiola caroliniana Species 0.000 description 1
- 235000010703 Modiola caroliniana Nutrition 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 235000019606 astringent taste Nutrition 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 230000007760 free radical scavenging Effects 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 description 1
- 239000007968 orange flavor Substances 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
- A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
- A24B15/302—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by natural substances obtained from animals or plants
- A24B15/303—Plant extracts other than tobacco
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/10—Devices using liquid inhalable precursors
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Botany (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Storage Of Fruits Or Vegetables (AREA)
Abstract
The invention discloses an antioxidant electronic atomized liquid and a preparation method thereof, and relates to the technical field of electronic atomized liquid. The electronic atomized liquid consists of the following raw materials in percentage by weight: 5-10% of antioxidant nicotine organic acid salt, 35-50% of essence base solution, 35-55% of glycerol and 5-15% of propylene glycol; wherein the antioxidant organic acid salt of nicotine consists of nicotine, organic acid, grape seed extract and solvent. Based on the weight of the antioxidant organic acid salt of nicotine, the antioxidant organic acid salt consists of 10-20% of nicotine, 15-20% of organic acid, 0.2-0.5% of grape seed extract and 60-65% of solvent. The grape seed extract with the antioxidation function is applied to the electronic atomized liquid, so that the antioxidation capability of the electronic atomized liquid is improved, the storage period of the atomized liquid is prolonged, and the quality of the atomized liquid is improved.
Description
Technical Field
The invention relates to the technical field of electronic atomized liquid, in particular to an antioxidant electronic atomized liquid and a preparation method thereof.
Background
The electronic atomization liquid is heated by the electronic atomization device, so that aerosol can be formed for sucking by consumers. The main components of the electronic aerosol generally include glycerin, propylene glycol, nicotine salts and specialty fragrances. However, the nicotine salt is applied to the electronic atomized liquid, and has the defect of low oxidation resistance, so that the electronic atomized liquid is poor in stability and extremely easy to oxidize, the color of the electronic atomized liquid is deepened, the storage period of the atomized liquid is influenced, and the suction taste of the electronic atomized liquid is influenced. Therefore, there is a need to develop an electronic atomized liquid with higher oxidation resistance.
In order to improve the antioxidation capability of the electronic atomized liquid, vitamin C, vitamin E, glutathione and the like are mostly adopted as antioxidants in the prior art, and compared with the oxidation speed of nicotine, the antioxidation capability of the antioxidants in the prior art scheme can not meet the antioxidation effect, and the situation of oxidative discoloration still occurs after the use.
Grape seed extract is a novel high-efficiency natural antioxidant substance which is extracted from grape seeds and cannot be synthesized in human body, and mainly comprises polyphenols including catechins and procyanidins (OPC). The antioxidant is a substance with the strongest antioxidant and free radical scavenging capacity found in the nature at present, has antioxidant activity which is 50 times that of vitamin E and 20 times that of vitamin C, can effectively scavenge redundant free radicals in human bodies, has the functions of deferring senility, enhancing immunity, resisting oxidation, resisting allergy, resisting fatigue, strengthening physique, improving sub-health state and the like, and can also improve symptoms such as dysphoria, irritability, dizziness, hypodynamia, hypomnesis and the like. At present, grape seed extract is mainly used in the fields of natural functional food additives, medical health products, daily chemical products and the like, and no application method of grape seed extract exists in the electronic atomization industry.
In order to overcome the technical defects, the invention provides the antioxidant electronic atomized liquid and the preparation method thereof, which are used for well fusing grape seed extract into the electronic atomized liquid, improving the antioxidant capacity of the electronic atomized liquid, prolonging the storage period of the atomized liquid and improving the quality of the atomized liquid.
Disclosure of Invention
In order to solve the technical problems, the invention provides an antioxidant electronic atomized liquid and a preparation method thereof, and the antioxidant electronic atomized liquid specifically comprises the following technical scheme:
in a first aspect, an antioxidant electronic atomized liquid is provided, which comprises the following raw materials in percentage by weight:
5-10% of antioxidant nicotine organic acid salt, 35-50% of essence base solution, 35-55% of glycerol and 5-15% of propylene glycol; wherein the antioxidant organic acid salt of nicotine consists of nicotine, organic acid, grape seed extract and solvent.
Further, the nicotine accounts for 10-20% of the weight of the antioxidant nicotine organic acid salt, the organic acid accounts for 15-20% of the weight of the antioxidant nicotine organic acid salt, the grape seed extract accounts for 0.2-0.5% of the weight of the antioxidant nicotine organic acid salt, and the solvent accounts for 60-65% of the weight of the antioxidant nicotine organic acid salt.
Preferably, the nicotine is 20% by weight of the antioxidant organic acid salt of nicotine.
Further, the preparation method of the grape seed extract comprises the following steps:
(1) Drying and crushing grape seeds, and sieving with a 60-80 mesh sieve to obtain grape seed powder;
(2) Adding cellulase and water which is 2-3 times of the weight of the grape seed powder into the grape seed powder, and soaking for 15-18h at 28-32 ℃;
(3) Extracting soaked grape seed powder with water for 2-4 times at 35-45deg.C, filtering, mixing the water extractive solutions, and freeze drying to obtain grape seed extract.
Preferably, in the preparation method of the grape seed extract, in the step (2), the weight of water used for soaking the grape seed powder is 2 times that of the grape seed powder, and the soaking time is 16 hours.
Further, in the preparation method of the grape seed extract, in the step (3), water is continuously added into the soaked grape seed powder for extraction for 3 times, the water extraction temperature is 40 ℃, water which is 5 times of the weight of the grape seed powder is added for the first time for extraction for 3 hours, water which is 3 times of the weight of the grape seed powder is added for the second time for extraction for 2 hours, water extract II is obtained by filtration, water which is 1 time of the weight of the grape seed powder is added for the third time for extraction for 1 hour, water extract III is obtained by filtration, and the water extract I, the water extract II and the water extract III are combined and freeze-dried to obtain the grape seed extract.
Further, in the preparation method of the grape seed extract, in the step (2), the enzyme activity of the cellulase ranges from 600U/mg to 900U/mg, and the weight ratio of the cellulase to the grape seed powder is 1:5000.
Preferably, the preparation method of the antioxidant nicotine organic acid salt comprises the following steps: mixing nicotine, organic acid, grape seed extract and solvent under stirring to obtain antioxidant organic acid salt of nicotine.
Further, the organic acid is one or more of benzoic acid, acetic acid, propionic acid, butyric acid, 3, 5-dihydroxybenzoic acid, levulinic acid, lactic acid, malic acid, citric acid and tartaric acid.
Further, the solvent is one or more of food-grade glycerol, food-grade ethanol and food-grade propylene glycol.
Further, the essence base liquid is one or more of strawberry-flavor essence base liquid, apple-flavor essence base liquid, mango-flavor essence base liquid, grape-flavor essence base liquid, mung-bean-flavor essence base liquid, red-bean-flavor essence base liquid, orange-flavor essence base liquid and tobacco-flavor essence base liquid.
Further, the nicotine content is 15-20mg/g.
In a second aspect, there is provided a method for preparing the antioxidant electronic atomized liquid according to the first aspect, including the steps of: and uniformly stirring and mixing the antioxidant nicotine organic acid salt, the essence base solution, the glycerol and the propylene glycol to obtain the antioxidant electronic atomized liquid.
The grape seed extract prepared by the method provided by the invention is added in the process of preparing nicotine salt, an antioxidant environment is provided for nicotine from the source, and the grape seed extract can be well fused into the electronic atomized liquid, so that the grape seed extract with an antioxidant effect can be well applied to the electronic atomized liquid, the antioxidant capacity of the electronic atomized liquid is improved, the storage period of the atomized liquid is prolonged, and the quality of the atomized liquid is improved.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely, and it is apparent that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
It should be understood that the terms "comprises" and "comprising," when used in this specification and the appended claims, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof.
It is also to be understood that the terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used in this specification and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.
It should be further understood that the term "and/or" as used in the present specification and the appended claims refers to any and all possible combinations of one or more of the associated listed items, and includes such combinations.
In order to more fully understand the technical content of the present invention, the following description and description of the technical solution of the present invention will be further presented with reference to specific embodiments.
The preparation method of grape seed extract comprises the following steps:
(1) Drying and crushing grape seeds, and sieving with a 60-80 mesh sieve to obtain grape seed powder;
(2) Adding cellulase and water which is 2-3 times of the weight of the grape seed powder into the grape seed powder, and soaking for 15-18h at 28-32 ℃;
(3) Extracting soaked grape seed powder with water for 2-4 times at 35-45deg.C, filtering, mixing the water extractive solutions, and freeze drying to obtain grape seed extract.
Preferably, in the preparation method of the grape seed extract, in the step (2), the weight of water used for soaking the grape seed powder is 2 times that of the grape seed powder, and the soaking time is 16 hours.
Preferably, in the step (3), water is continuously added into the soaked grape seed powder for extraction for 3 times, the water extraction temperature is 40 ℃, water which is 5 times of the weight of the grape seed powder is added for the first time for extraction for 3 hours, water which is 3 times of the weight of the grape seed powder is added for the second time for extraction for 2 hours, water which is 1 time of the weight of the grape seed powder is added for the third time for extraction for 1 hour, the water extract III is obtained by filtration, and the water extract I, the water extract II and the water extract III are combined and freeze-dried to obtain the grape seed extract.
Preferably, in the step (2), the enzyme activity of the cellulase ranges from 600U/mg to 900U/mg, and the weight ratio of the cellulase to the grape seed powder is 1:5000.
In the range of the enzyme activity, the hydrolysis effect of the cell wall of the grape seed is good, and the water-soluble polyphenols antioxidant substances such as catechins, procyanidins (OPC) and the like in the grape seed are fully extracted. Above this concentration range, the efficiency of grape seed cell wall hydrolysis is almost unchanged, below which the efficiency of grape seed cell wall hydrolysis is low.
By adopting the grape seed extract prepared by the preparation method, the water-soluble polyphenols antioxidant substances such as catechins, procyanidins (OPC) and the like in grape seeds can be fully extracted, so that the grape seed extract has high-efficiency antioxidant effect in electronic atomized liquid.
The preparation method of the antioxidant nicotine organic acid salt comprises the following steps:
mixing nicotine, organic acid, grape seed extract and solvent under stirring (no solid residue) to obtain antioxidant organic acid salt of nicotine.
By introducing grape seed extract during the preparation of nicotine salt, an antioxidant environment can be provided for nicotine from the source, the antioxidant effect is exerted to the greatest extent, and the used organic acid can better neutralize the alkalinity of nicotine, so that consumers can provide better sucking experience during sucking.
The preparation method of the antioxidant electronic atomized liquid comprises the following steps:
and uniformly stirring and mixing the antioxidant nicotine organic acid salt, the essence base solution, the glycerol and the propylene glycol to obtain the antioxidant electronic atomized liquid.
Example 1
An antioxidant electronic atomized liquid consists of the following raw materials in percentage by weight:
8.5g of antioxidant nicotine organic acid salt, 42g of essence base solution (strawberry flavor essence base solution), 35g of glycerol and 11g of propylene glycol; wherein the antioxidant organic acid salt of nicotine consists of nicotine, organic acid (benzoic acid, lactic acid, levulinic acid), grape seed extract and solvent (food-grade glycerol).
The said nicotine is 20% of the weight of the organic acid salt of the anti-oxidation nicotine, the said organic acid is 18% of the weight of the organic acid salt of the anti-oxidation nicotine (wherein, benzoic acid is 14%, lactic acid is 2.4%, levulinic acid is 1.6%), the said grape seed extract is 0.4% of the weight of the organic acid salt of the anti-oxidation nicotine, the said solvent is 61.6% of the weight of the organic acid salt of the anti-oxidation nicotine.
The nicotine content is 17mg/g.
The preparation method of the grape seed extract of the embodiment 1 comprises the following steps:
(1) Drying and crushing 50g of grape seeds, and sieving with a 60-mesh sieve to obtain grape seed powder;
(2) Adding 10mg of cellulase (enzyme activity of cellulase: 800U/mg) and 100mL of water into grape seed powder, soaking at 28deg.C for 16h;
(3) Continuously adding water into the soaked grape seed powder for extraction for 3 times, wherein the water extraction temperature is 40 ℃, 250mL of water is added for the first time for extraction for 3 hours, filtering to obtain a first water extract, 150mL of water is added for the second time for extraction for 2 hours, filtering to obtain a second water extract, 50mL of water is added for the third time for extraction for 1 hour, filtering to obtain a third water extract, and mixing the first water extract, the second water extract and the third water extract, and freeze-drying to obtain the grape seed extract. The grape seed extract is in the form of mauve transparent oil.
The method for preparing the antioxidant nicotine organic acid salt in the embodiment 1 comprises the following steps:
5g of nicotine, 4.5g of organic acid (wherein, 3.5g of benzoic acid, 0.6g of lactic acid and 0.4g of levulinic acid), 0.1g of grape seed extract and 15.4g of solvent (food-grade glycerin) are stirred and mixed uniformly (without solid residue) to obtain the antioxidant nicotine organic acid salt.
The preparation method of the antioxidant electronic atomized liquid of the embodiment 1 comprises the following steps:
8.5g of antioxidant nicotine organic acid salt, 42g of essence base solution (strawberry flavor essence base solution), 35g of glycerol and 11g of propylene glycol are stirred and mixed uniformly to obtain the antioxidant electronic atomized liquid.
Examples 2 to 7
Examples 2-7 differ from example 1 in the preparation of grape seed extract, the remaining conditions being the same, the specific parameters for the preparation of grape seed extract of the antioxidant electrospray solutions of examples 2-7 are shown in Table 1 below:
TABLE 1 examples 2-7 preparation parameters of grape seed extract of antioxidant electronic atomization liquid
Examples 8 to 14
Examples 8-14 differ from example 1 in the content of the components of the organic acid salt of the anti-oxidant nicotine, and all the other conditions are the same, and the specific content of the organic acid salt of the anti-oxidant nicotine in the anti-oxidant electronic atomizing liquid of examples 8-14 is shown in table 2 below:
TABLE 2 antioxidant nicotine organic acid salt component content of antioxidant electronic atomized solutions of examples 8-14
Examples 15 to 21
Examples 15 to 21 differ from example 1 in the content and types of components of the antioxidant electronic atomized liquid, and the other conditions were the same, and the specific content and types of components of the antioxidant electronic atomized liquid of examples 15 to 21 are shown in Table 3 below:
TABLE 3 component content and type of antioxidant electronic atomized liquid of examples 15-21
Comparative examples 1 to 7
Comparative examples 1 to 7 are different from example 1 in the content of the antioxidant nicotine organic acid salt component, and the other conditions are the same, and the specific content of the antioxidant nicotine organic acid salt of the antioxidant electronic atomized liquid of comparative examples 1 to 7 is shown in the following table 4:
TABLE 4 comparative examples 1-7 antioxidant organic acid salt component content of antioxidant electronic atomized solutions
Comparative examples 8 to 10
Comparative examples 8-10 differ from example 1 in the organic acid content of the antioxidant nicotine organic acid salt component, all under the same conditions. Comparative examples 8-10 specific component contents of the antioxidant nicotine organic acid salts of the antioxidant electronic atomized solutions are shown in table 5 below:
TABLE 5 comparative examples 8-10 antioxidant organic acid salt component content of antioxidant electronic atomized solutions
Comparative examples 11 to 12
Comparative examples 11-12 differ from example 1 in the amount of nicotine in the antioxidant nicotine organic acid salt component, and the remaining conditions are the same. Comparative examples 11-12 specific component contents of the antioxidant nicotine organic acid salts of the antioxidant electronic atomized solutions are shown in table 6 below:
TABLE 6 comparative examples 11-12 antioxidant organic acid salt component content of antioxidant electronic atomized solutions
Comparative examples 13 to 14
Comparative examples 13 to 14 are different from example 1 in the content of the organic acid salt of antioxidant nicotine in the antioxidant electronic atomized liquid, and the other conditions are the same. Comparative examples 13-14 the contents of specific components of the antioxidant electronic atomized liquid are shown in table 7 below:
table 7 comparative examples 13 to 14 antioxidant electronic atomized liquid component contents
Comparative examples 15 to 17
Comparative example 15 is different from example 1 in that vitamin C is used instead of the antioxidant organic acid salt of nicotine in the antioxidant electronic atomizer, and the other conditions are the same. Comparative example 16 is different from example 1 in that vitamin E is used instead of the antioxidant organic acid salt of nicotine in the antioxidant electronic atomizer, and the other conditions are the same. Comparative example 17 is different from example 1 in that glutathione is used instead of the antioxidant organic acid salt of nicotine in the antioxidant electronic nebulizing liquid, and the other conditions are the same.
Performance test
After the preparation of the electronic atomized liquid is finished, sampling is carried out in 0, 30 and 90 days of storage, 20 professional electronic atomized liquid sensory evaluators are selected to evaluate the atomized liquid samples respectively, and the average value is obtained. The evaluation items and scoring criteria are shown in table 8 below:
table 8 evaluation items and scoring criteria
Performance tests were performed on the antioxidant electronic atomized solutions of examples 1 to 21 and comparative examples 1 to 17, and the test results are shown in tables 9 to 14:
table 9 stores the results of the antioxidant electronic atomized liquid performance test of examples 1-21 sampled over 0 day
Table 10 stores the results of the antioxidant electronic atomized liquid performance test of comparative examples 1 to 17 sampled for 0 day
Table 11 stores the results of the antioxidant electronic atomized liquid performance test of examples 1-21 sampled for 30 days
Table 12 stores the results of the 30-day sampling test for the performance of the antioxidant electrospray liquid of comparative examples 1 to 17
Table 13 stores the results of the antioxidant electronic atomized liquid performance test of examples 1-21 sampled over 90 days
Table 14 stores the results of the antioxidant electronic atomized liquid performance test of comparative examples 1 to 17 sampled over 90 days
As shown in the test results of the performance test of the antioxidant electronic atomized liquid in tables 9-14, the antioxidant electronic atomized liquid of the embodiment of the invention has the advantages of oxidation of nicotine in the atomized liquid, reduced throat feeling, reduced irritation, increased flexibility and increased miscellaneous flavor along with the increase of the storage time. As can be seen from the performance detection experimental results of the embodiment 1 and the embodiments 2-7, the grape seed extract prepared by the preparation method of the grape seed extract has better antioxidation capability, the grape seed extract has smaller influence on essence base liquid, has rich taste and layering, is not easy to oxidize and rancidity by electronic atomization liquid, has lighter impurity taste and has pure taste. The results of the performance detection experiments of the embodiment 1 and the embodiments 8-14 show that the antioxidant nicotine organic acid salt has better antioxidant capacity, the influence of the antioxidant nicotine organic acid salt on the essence base liquid is smaller, the taste is rich in level, the electronic atomization liquid is not easy to oxidize and rancid, and the electronic atomization liquid has lighter impurity taste and pure taste. As can be seen from the performance detection experimental results of the embodiment 1 and the embodiments 15-21, the antioxidation electronic atomized liquid prepared by adopting the formula of the embodiment of the invention has rich taste and layering, is not easy to oxidize and rancid, has lighter impurity taste and has pure taste.
The results of the performance test experiments of the embodiment 1 and the comparative examples 1-4 show that the antioxidant electronic atomized liquid prepared in the comparative examples 1-4 has serious nicotine oxidation after long-time storage, has dark color, slightly astringent and bitter taste, has larger influence on essence base liquid, and improves oxidation conditions along with the increase of the addition amount of grape seed extract. As can be seen from the results of the performance test experiments of example 1 and comparative examples 5 to 7, the excessive use of grape seed extract did not greatly increase the oxidation resistance of the electrospray solution.
In addition, as can be seen from the results of the performance test experiments of the combination of the example 1 and the comparative examples 8 to 10, the antioxidant electronic atomized liquid prepared with the content of the organic acid in the antioxidant nicotine organic acid salt component not in the range of the present invention has poor effect. As can be seen from the results of performance test experiments of example 1 and comparative examples 11 to 12, the antioxidant electronic atomized liquid prepared with the content of nicotine in the antioxidant nicotine organic acid salt component not in the range of the present invention has poor effect. As can be seen from the performance test results of the combination of the example 1 and the comparative examples 13 to 14, the antioxidant electronic atomized liquid prepared by the method that the content of the antioxidant nicotine organic acid salt in the antioxidant electronic atomized liquid is not in the range of the invention has poor effect.
In addition, as can be seen from the results of the performance test experiments of example 1 and comparative examples 15 to 17, the antioxidant electronic aerosol prepared by using vitamin C or vitamin E or glutathione instead of the antioxidant nicotine organic acid salt has poor effect.
In summary, the grape seed extract prepared by the method provided by the invention is added in the process of preparing nicotine salt, an antioxidant environment is provided for nicotine from the source, and the grape seed extract can be well fused into the electronic atomized liquid, so that the grape seed extract with the antioxidant effect can be well applied to the electronic atomized liquid, the antioxidant capacity of the electronic atomized liquid is improved, the storage period of the atomized liquid is prolonged, and the quality of the atomized liquid is improved.
While the invention has been described with reference to certain preferred embodiments, it will be understood by those skilled in the art that various changes and substitutions of equivalents may be made and equivalents will be apparent to those skilled in the art without departing from the scope of the invention. Therefore, the protection scope of the invention is subject to the protection scope of the claims.
Claims (10)
1. An antioxidant electronic atomized liquid is characterized by comprising the following raw materials in percentage by weight:
5-10% of antioxidant nicotine organic acid salt, 35-50% of essence base solution, 35-55% of glycerol and 5-15% of propylene glycol; wherein the antioxidant organic acid salt of nicotine consists of nicotine, organic acid, grape seed extract and solvent.
2. The antioxidant electronic atomized liquid of claim 1 wherein the nicotine comprises 10-20% by weight of the antioxidant nicotine organic acid salt, the organic acid comprises 15-20% by weight of the antioxidant nicotine organic acid salt, the grape seed extract comprises 0.2-0.5% by weight of the antioxidant nicotine organic acid salt, and the solvent comprises 60-65% by weight of the antioxidant nicotine organic acid salt.
3. The antioxidant electronic atomized liquid of claim 2 wherein the method of preparing grape seed extract comprises the steps of:
(1) Drying and crushing grape seeds, and sieving with a 60-80 mesh sieve to obtain grape seed powder;
(2) Adding cellulase and water which is 2-3 times of the weight of the grape seed powder into the grape seed powder, and soaking for 15-18h at 28-32 ℃;
(3) Extracting soaked grape seed powder with water for 2-4 times at 35-45deg.C, filtering, mixing the water extractive solutions, and freeze drying to obtain grape seed extract.
4. The method of preparing an antioxidant electronic atomized liquid according to claim 3, wherein in the step (3), water is continuously added into the soaked grape seed powder for extraction for 3 times, the water extraction temperature is 40 ℃, water which is 5 times of the weight of the grape seed powder is added for the first time for extraction for 3 hours, water which is 3 times of the weight of the grape seed powder is added for the second time for extraction for 2 hours, water which is 1 time of the weight of the grape seed powder is added for the third time for filtration for extraction for 1 hour, water extract three is obtained by filtration, and the water extract one, the water extract two and the water extract three are combined and freeze-dried to obtain the grape seed extract.
5. The antioxidant electronic atomized liquid of claim 4 wherein in step (2) the cellulase has an enzyme activity ranging from 600 to 900U/mg and the weight ratio of cellulase to grape seed powder is 1:5000.
6. The antioxidant electronic atomized of claim 2 wherein the organic acid is one or more of benzoic acid, acetic acid, propionic acid, butyric acid, 3, 5-dihydroxybenzoic acid, levulinic acid, lactic acid, malic acid, citric acid, tartaric acid.
7. The antioxidant electronic spray of claim 6 wherein the solvent is one or more of food grade glycerin, food grade ethanol, and food grade propylene glycol.
8. The antioxidant electronic atomized liquid of claim 1, wherein the essence base liquid is one or more of strawberry-flavored essence base liquid, apple-flavored essence base liquid, mango-flavored essence base liquid, grape-flavored essence base liquid, mung bean-flavored essence base liquid, red bean-flavored essence base liquid, orange-flavored essence base liquid, and tobacco-flavored essence base liquid.
9. The antioxidant electronic aerosol as set forth in claim 1, wherein said nicotine is present in an amount of 15 to 20mg/g.
10. The method for preparing the antioxidant electronic atomized liquid according to any one of claims 1-9, comprising the steps of: and uniformly stirring and mixing the antioxidant nicotine organic acid salt, the essence base solution, the glycerol and the propylene glycol to obtain the antioxidant electronic atomized liquid.
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Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110293535A1 (en) * | 2009-02-11 | 2011-12-01 | Heglund, A.S. | Composition for buccal absorption of nicotine for the purpose of smoking cessation |
| CN103627514A (en) * | 2012-08-24 | 2014-03-12 | 曹以鉴 | Method for extracting grape seed oil from grape seeds |
| CN104068467A (en) * | 2014-07-01 | 2014-10-01 | 安徽中烟工业有限责任公司 | Electronic cigarette liquid rich in plant flavone |
| WO2015061926A1 (en) * | 2013-10-29 | 2015-05-07 | 张丽娜 | A method for extracting grape seed oil by utilizing cellulase |
| CN106037012A (en) * | 2016-07-18 | 2016-10-26 | 福建中烟工业有限责任公司 | Electronic cigarette liquid |
| CN112674345A (en) * | 2019-10-17 | 2021-04-20 | 宁波合康生物医药科技有限公司 | Cyclodextrin additive and preparation method and application thereof |
| CN114601193A (en) * | 2022-04-27 | 2022-06-10 | 深圳市艾普生物科技有限公司 | Preparation method and application of antioxidant nicotine salt |
| CN115119957A (en) * | 2022-06-28 | 2022-09-30 | 深圳市艾普生物科技有限公司 | Antioxidant electronic cigarette oil and preparation method thereof |
| CN115281366A (en) * | 2022-06-28 | 2022-11-04 | 深圳市艾普生物科技有限公司 | Preparation method and application of antioxidant nicotine salt |
-
2023
- 2023-09-05 CN CN202311135246.5A patent/CN117099995A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110293535A1 (en) * | 2009-02-11 | 2011-12-01 | Heglund, A.S. | Composition for buccal absorption of nicotine for the purpose of smoking cessation |
| CN103627514A (en) * | 2012-08-24 | 2014-03-12 | 曹以鉴 | Method for extracting grape seed oil from grape seeds |
| WO2015061926A1 (en) * | 2013-10-29 | 2015-05-07 | 张丽娜 | A method for extracting grape seed oil by utilizing cellulase |
| CN104068467A (en) * | 2014-07-01 | 2014-10-01 | 安徽中烟工业有限责任公司 | Electronic cigarette liquid rich in plant flavone |
| CN106037012A (en) * | 2016-07-18 | 2016-10-26 | 福建中烟工业有限责任公司 | Electronic cigarette liquid |
| CN112674345A (en) * | 2019-10-17 | 2021-04-20 | 宁波合康生物医药科技有限公司 | Cyclodextrin additive and preparation method and application thereof |
| CN114601193A (en) * | 2022-04-27 | 2022-06-10 | 深圳市艾普生物科技有限公司 | Preparation method and application of antioxidant nicotine salt |
| CN115119957A (en) * | 2022-06-28 | 2022-09-30 | 深圳市艾普生物科技有限公司 | Antioxidant electronic cigarette oil and preparation method thereof |
| CN115281366A (en) * | 2022-06-28 | 2022-11-04 | 深圳市艾普生物科技有限公司 | Preparation method and application of antioxidant nicotine salt |
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