CN116869579A - An animal tissue sampling device - Google Patents

Abstract

The application discloses animal tissue sampling equipment, which relates to the field of animal tissue sampling, and comprises a puncture rod and a sampling mechanism, wherein the puncture rod is of a hollow structure, the sampling mechanism is arranged on the puncture rod, the sampling mechanism comprises a sampling window and an enucleation cutting assembly, the sampling window is arranged on the puncture rod, the enucleation cutting assembly penetrates through and can be movably arranged at the inner side of the sampling window, the enucleation cutting assembly comprises an enucleation cutting rod, longitudinal enucleation cutting teeth and radial enucleation cutting teeth, the enucleation cutting rod can be movably arranged in the puncture rod, the radial enucleation cutting teeth are symmetrically arranged at two sides of an annular surface of the enucleation cutting rod, the longitudinal enucleation cutting teeth are arranged at two sides of the side surface of the end part of the enucleation cutting rod, and the radial enucleation cutting teeth and the longitudinal enucleation cutting teeth are connected in a head-tail mode to form an enucleation cutting window, and the enucleation cutting window corresponds to the sampling window. According to the animal tissue sampling equipment provided by the embodiment of the application, the longitudinal enucleation teeth and the radial enucleation teeth are matched to firmly bite the animal tissue, and the animal tissue can be cut from the front, back, left and right directions, so that the animal tissue can be effectively enucleated for sampling.

Description

An animal tissue sampling device

Technical field

The present application relates to the technical field of animal tissue sampling, and in particular to an animal tissue sampling device.

Background technique

In animal or human tissue sampling, puncture is commonly used to sample specific subcutaneous tissue, and then biopsy the tissue, referred to as puncture biopsy. Generally speaking, puncture biopsy is a more convenient and easy-to-operate inspection method. The wound formed by puncture It is very small, causes little damage to body tissues, and does not cause a large amount of bleeding. At the same time, the risk of infection to the patient during the operation and recovery process is also very low, the process safety factor is high, and it also has high accuracy.

Some of the existing puncture and sampling equipment use negative pressure suction, such as commonly used negative pressure puncture needles. There are also some more advanced puncture equipment that reach the tissue and dig out the tissue through a cutting action. This method affects the tissue. The damage is less than that of negative pressure suction. Existing equipment, such as a living kidney tissue puncture sampling needle disclosed in Chinese patent CN207136869U, separates the sample trapped in the sample storage tank from the body by rotating the rotary cutting tube in the middle. , the wound area is small, but the patented sample storage tank only has blades on both sides of the edge, and there is only rotational cutting. The tissue cutting dimensions are small. The sample storage tank and the blades on both sides cannot stably clamp the tissue, and the tissue is easily removed from the sample storage tank. If it slips, the sampling success rate is not high.

Contents of the invention

The present application aims to solve, at least to a certain extent, one of the technical problems in the related art.

To this end, the first purpose of this application is to provide an animal tissue sampling device that can bite the animal tissue firmly and cut from the front, back, left and right directions, so that the animal tissue can be effectively cut out and sampled.

In order to achieve the above object, the first embodiment of the present application proposes an animal tissue sampling device. An animal tissue sampling device includes a puncture rod and a sampling mechanism, wherein the puncture rod is a hollow structure, and the sampling mechanism is configured On the puncture rod, the sampling mechanism includes a sampling window and a cutting assembly, wherein the sampling window is opened on the puncture rod, and the cutting assembly penetrates and is movably arranged inside the sampling window, and the cutting assembly includes Cutting rod, longitudinal cutting teeth and radial cutting teeth, wherein the cutting rod is a hollow structure, the cutting rod is movably arranged inside the puncture rod, and the radial cutting teeth are symmetrically arranged inside the puncture rod. On both sides of the annular surface of the cutting rod, the longitudinal cutting teeth are arranged on both sides of the end side of the cutting rod, and the radial cutting teeth and the longitudinal cutting teeth are connected end to end to form a cutting window, and the The cutting window and the sampling window correspond to each other.

The animal tissue sampling device in the embodiment of the present application can firmly bite the animal tissue through the cooperation of the longitudinal cutting teeth and the radial cutting teeth, and can cut from the front, rear, left and right directions, so that the animal tissue can be effectively cut and sampled.

In addition, the animal tissue sampling equipment proposed above in this application may also have the following additional technical features:

In one embodiment of the present application, an anti-detaching tooth is provided on the inside of the radial cutting teeth. The angle between the anti-detaching teeth and the radial cutting teeth is greater than 90°. The anti-detaching teeth are located on the cutting edge. the inside of the window.

In one embodiment of the present application, cutting edges are provided on both sides of the sampling window along the axial direction of the puncture rod, and the cutting edges have a convex streamlined structure.

In one embodiment of the present application, the puncture rod is provided with a sampling depth scale, the puncture end of the puncture rod is provided with a puncture head, and the puncture head is provided with a guide component that drives the elastic reset of the cutting rod, The guide assembly includes a guide chute, a spring and a guide post. The guide chute is provided inside the puncture head. The guide post is slidably disposed inside the guide chute. The two ends of the spring are respectively connected with the guide chute. The bottom of the cutting rod is connected to one end of the guide column, the other end of the guide column is provided with a polygonal chuck, and one end of the cutting rod is provided with a polygonal slot that matches the polygonal chuck.

In one embodiment of the present application, a sample recovery mechanism is provided at one end of the cutting rod. The sample recovery mechanism includes a sample rod and a pull handle. The sample rod is a hollow structure, and the sample rod has a hollow structure. One end is connected to the cutting rod, the sample rod is disposed through the interior of the puncture rod, and the pull-out handle is disposed at the other end of the sample rod.

In one embodiment of the present application, an interstitial fluid extraction mechanism is provided inside the sample rod. The interstitial fluid extraction mechanism includes a partition filter, a storage chamber, and a suction tube, wherein the storage chamber is provided inside the sample rod. , the baffle filter is arranged between the cutting rod and the storage chamber, and the storage chamber is connected to the chopping rod through the baffle filter, one end of the suction pipe is connected to the storage chamber, and the suction pipe The other end of the tube runs through the sample stem.

In one embodiment of the present application, the suction tube is provided with a sealing seat, the sealing seat is arranged inside the sample rod, and a plug is provided at the connection between the pull-out handle and the sample rod. The tube goes through the plug.

In one embodiment of the present application, a limited propulsion mechanism is provided outside the puncture rod. The limit propulsion mechanism includes a fixed seat, a piston piece and a hydraulic groove. The fixed seat is sleeved on the puncture rod and the sample rod. On the outside, the hydraulic groove is opened on the inner wall of the fixed seat, the end of the puncture rod facing away from the puncture end is slidably disposed in the hydraulic groove, and the piston piece is disposed on the end of the puncture rod facing away from the puncture end.

In one embodiment of the present application, a sealing sliding sleeve is provided between the sample rod and the fixed seat. The sealing sliding sleeve is set on the sample rod. A hydraulic joint is provided on the fixed seat. The hydraulic joint Connected to hydraulic tank.

In one embodiment of the present application, the edge portion of the sampling window is provided with sampling window cutting teeth.

Additional aspects and advantages of the application will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the application.

Description of the drawings

The above and/or additional aspects and advantages of the present application will become apparent and readily understood from the following description of the embodiments in conjunction with the accompanying drawings, in which:

Figure 1 is a schematic structural diagram of an animal tissue sampling device according to an embodiment of the present application;

Figure 2 is a front cross-sectional view of an animal tissue sampling device according to another embodiment of the present application;

Figure 3 is a partial cross-sectional view of an animal tissue sampling device according to another embodiment of the present application;

Figure 4 is a left cross-sectional view of an animal tissue sampling device according to another embodiment of the present application;

Figure 5 is an enlarged view of A in Figure 4.

As shown in the figure: 1. Puncture head; 2. Sampling mechanism; 21. Sampling window; 22. Guide assembly; 221. Guide chute; 222. Spring; 223. Guide column; 24. Sampling window cutting teeth; 23. Cutting component; 231. Cutting rod; 232. Longitudinal cutting teeth; 233. Radial cutting teeth; 234. Preventing tooth removal; 235. Cutting window; 3. Puncture rod; 31. Sampling depth scale; 32 , cutting blade; 4. limit propulsion mechanism; 41. fixed seat; 42. piston piece; 43. hydraulic tank; 44. hydraulic joint; 45. sealing sliding sleeve; 5. sample recovery mechanism; 51. sample rod; 52. Plug; 53. Pull handle; 6. Tissue fluid extraction mechanism; 61. Barrier filter; 62. Storage chamber; 63. Sealing seat; 64. Suction tube.

Detailed ways

The embodiments of the present application are described in detail below. Examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements with the same or similar functions. The embodiments described below with reference to the drawings are exemplary and are intended to explain the present application, but should not be construed as limiting the present application. On the contrary, the embodiments of the present application include all changes, modifications and equivalents falling within the spirit and scope of the appended claims.

The animal tissue sampling device according to the embodiment of the present application will be described below in conjunction with the accompanying drawings.

As shown in Figures 1-5, the animal tissue sampling device according to the embodiment of the present application includes a puncture rod 3 and a sampling mechanism 2. The puncture rod 3 is a hollow structure, and the sampling mechanism 2 is arranged on the puncture rod 3.

The sampling mechanism 2 includes a sampling window 21 and a cutting assembly 23. The sampling window 21 is opened on the puncture rod 3, and the cutting assembly 23 penetrates and is movably arranged inside the sampling window 21. The cutting assembly 23 includes a cutting rod 231, Longitudinal cutting teeth 232 and radial cutting teeth 233 .

Among them, the cutting rod 231 is a hollow structure, the cutting rod 231 is movably arranged inside the puncture rod 3, the radial cutting teeth 233 are symmetrically arranged on both sides of the annular surface of the cutting rod 231, and the longitudinal cutting teeth 232 are arranged on Both sides of the end side of the cutting rod 231 are cut out, and the radial cutting teeth 233 and the longitudinal cutting teeth 232 are connected end-to-end to form a cutting window 235. The cutting window 235 and the sampling window 21 correspond to each other.

Specifically, when a biopsy sample needs to be taken from a specific location of the animal's subcutaneous tissue, the operator first inserts the puncture end of the puncture rod 3 under the animal's skin. It should be noted that during the puncture sampling process, it can be used in conjunction with an X-ray machine to ensure accurate Check the sampling position of the puncture rod 3 until the sampling window 21 at the bottom of the puncture rod 3 reaches the sampling position. The operator controls the rotation of the cutting rod 231 so that the cutting window 235 and the sampling window 21 correspond to each other, and then the sampling window 21 is The tissue will be compressed and enter the cutting window 235. The operator moves the cutting rod 231 left and right and controls the rotation of the cutting rod 231. The serrated longitudinal cutting teeth 232 and radial cutting teeth 233 bite the animal tissue firmly. Prevent the tissue from slipping, and can cut from the front, back, left and right directions, so that the animal tissue falls into the cutting window 235 after cutting out, and then the operator controls the cutting rod 231 to rotate, so that the cutting window 235 and the sampling window 21 are staggered from each other, and sampling The window 21 is closed, and the cut sampling tissue is rolled into the cutting rod 231. Finally, the puncture rod 3 is pulled out, the sampling window 21 is opened, and the tissue is taken out.

In the embodiment of the present application, as shown in Figure 2-4, the anti-separation teeth 234 are provided on the inside of the radial cutting teeth 233. The angle between the anti-separation teeth 234 and the radial cutting teeth 233 is greater than 90°. The teeth 234 are located inside the cutting window 235. When the tissue enters the cutting window 235, the angle between the teeth 234 and the anti-detaching tooth 234 is an acute angle, which facilitates the tissue to enter the bottom of the cutting window 235. When the tissue is pulled away from the cutting window 235 by force, at this time The angle between the tissue in the cutting window 235 and the anti-exfoliation 234 is an obtuse angle, and the tissue is blocked from bite by the anti-exfoliation 234 .

Specifically, when the cut tissue enters the bottom of the cut out window 235, the tissue will be blocked by the anti-detaching 234 and stuck at the bottom of the cut out window 235 and cannot slip out, which facilitates further engagement of the tissue that needs to be cut out and facilitates zigzag longitudinal cut out. The cutting teeth 232 and the radial cutting teeth 233 cut off animal tissue.

In the embodiment of the present application, as shown in Figures 1 and 4, the sampling window 21 is provided with cutting edges 32 on both sides along the axial direction of the puncture rod 3. The cutting edges 32 have a convex streamlined structure. Specifically, the convex structure On the one hand, the cutting edge 32 strengthens the structural strength of the puncture rod 3 and prevents the puncture rod 3 from breaking at the sampling window 21. Furthermore, the sampling window 21 can be designed to be relatively large to facilitate the tissue to fall into the sampling window 21 and facilitate the cutting of the tissue.

In addition, the cutting edge 32 cuts and opens the tissue outside the puncture rod 3 to facilitate smooth puncture of the puncture rod 3 and reduce puncture resistance.

In addition, the cutting edge 32 of the convex structure supports and pulls the tissue at the cutting edge 32, so that the tissue at the sampling window 21 is drawn into the sampling window 21, making it easier to cut the tissue.

In the embodiment of the present application, as shown in Figures 1-3, the puncture rod 3 is provided with a sampling depth scale 31 to facilitate viewing of the puncture depth. The puncture end of the puncture rod 3 is provided with a puncture head 1, and the puncture head 1 is provided with a puncture head 1 inside. The cutting rod 231 is driven to elastically reset the guide assembly 22. The guide assembly 22 includes a guide chute 221, a spring 222 and a guide column 223.

Among them, the guide chute 221 is provided inside the puncture head 1, and the guide post 223 is slidably disposed inside the guide chute 221. The two ends of the spring 222 are respectively connected to the bottom of the guide chute 221 and one end of the guide post 223. The guide post 223 is The other end is provided with a polygonal chuck, and one end of the cutting rod 231 is provided with a polygonal chuck that matches the polygonal chuck.

Specifically, when the cutting rod 231 is rotating and cutting out the tissue, the human eye cannot directly observe the cutting situation because the cutting rod 231 is within the tissue. After the cutting rod 231 completes cutting out the tissue, release the cutting rod. 231, the cutting rod 231 will be reset by the elastic force and torsion of the spring 222, as shown in Figure 3, so that the cutting rod 231 can be reset without any force, and the cutting window 235 and the sampling window 21 are staggered, so that the tissue is wrapped in the cutting window. in the cutting rod 231 to prevent tissue from slipping.

In the embodiment of the present application, as shown in Figure 2-3, one end of the cutting rod 231 is provided with a sample recovery mechanism 5. The sample recovery mechanism 5 includes a sample rod 51 and a pull handle 53. The sample rod 51 is a hollow structure. , one end of the sample rod 51 is connected to the cutting rod 231 , the sample rod 51 is disposed through the interior of the puncture rod 3 , and the pull handle 53 is disposed at the other end of the sample rod 51 .

Specifically, the operator drives the sample rod 51 to move by pulling the handle 53, and the sample rod 51 drives the cutting rod 231 to move in the puncture rod 3 to facilitate the control of the cutting rod 231. When the sample rod 51 is completely removed from the puncture rod 3, When withdrawing, the operator can take out the tissue in the cutting rod 231, and the puncture rod 3 does not need to be pulled out from the animal tissue, so multiple samples can be taken.

In the embodiment of the present application, as shown in FIGS. 2-3 , a tissue fluid extraction mechanism 6 is provided inside the sample rod 51 . The tissue fluid extraction mechanism 6 includes a barrier filter 61 , a storage chamber 62 and a suction tube 64 .

Among them, the storage chamber 62 is arranged inside the sample rod 51, the partition filter 61 is arranged between the cutting rod 231 and the storage chamber 62, and the storage chamber 62 is connected to the cutting rod 231 through the partition filter 61, and the suction tube One end of the suction pipe 64 is connected to the storage chamber 62 , and the other end of the suction pipe 64 penetrates the sample rod 51 .

Further, a sealing seat 63 is set on the suction tube 64 , and the sealing seat 63 is arranged inside the sample rod 51 . A plug 52 is provided at the connection between the pull handle 53 and the sample rod 51 , and the suction tube 64 passes through the plug 52 .

Specifically, during the process of cutting out the tissue, when the cutting window 235 is aligned with the sampling window 21, the operator can also apply a negative pressure suction force to the suction tube 64. At this time, the tissue fluid outside the sampling window 21 is sucked in by the negative pressure. The tissue fluid is cut out in the window 235 and then filtered through the partition filter 61 into the storage chamber 62 , and then the tissue fluid is extracted through the suction tube 64 .

By using the suction tube 64, a negative pressure suction force can also be applied to the sampling window 21, so that more tissue can enter the sampling window 21 when cutting out the tissue, thereby facilitating tissue cutting.

In the embodiment of the present application, as shown in Figures 2-3, a limiting propulsion mechanism 4 is provided outside the puncture rod 3. The limited propulsion mechanism 4 includes a fixed seat 41, a piston piece 42 and a hydraulic groove 43.

Among them, the fixed seat 41 is sleeved on the outside of the puncture rod 3 and the sample rod 51, the hydraulic groove 43 is opened on the inner wall of the fixed seat 41, the end of the puncture rod 3 away from the puncture end is slidably arranged in the hydraulic groove 43, and the piston piece 42 is provided On the end of the puncture rod 3 away from the puncture end.

Further, a sealing sliding sleeve 45 is provided between the sample rod 51 and the fixed seat 41. The sealing sliding sleeve 45 is sleeved on the sample rod 51. A hydraulic joint 44 is provided on the fixed seat 41, and the hydraulic joint 44 is connected with the hydraulic tank 43. .

Specifically, when the puncture rod 3 penetrates deeply into animal tissue, when the puncture head 1 reaches a predetermined approximate position, the operator connects the hydraulic oil through the hydraulic joint 44, and the hydraulic oil enters the hydraulic tank 43 to push the puncture rod 3 to move accurately. , to facilitate the puncture rod 3 to accurately reach the designated puncture sampling position.

In the embodiment of the present application, as shown in Figures 2-3, the edge part of the sampling window 21 is provided with sampling window cutting teeth 24. Specifically, the sampling window cutting teeth 24 cooperate with the serrated longitudinal cutting teeth 232 and The radial cutting teeth 233 bite the animal tissue firmly to prevent the tissue from slipping, and facilitate tissue cutting from the front, rear, left and right directions.

In summary, the animal tissue sampling equipment of the embodiment of the present application can firmly bite the animal tissue through the cooperation of the longitudinal cutting teeth and the radial cutting teeth, and can cut from the front, rear, left and right directions, so that the animal tissue can be effectively cut and sampled.

In the description of this specification, the terms "first" and "second" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly indicating the number of indicated technical features. Therefore, features defined as "first" and "second" may explicitly or implicitly include at least one of these features. In the description of this application, "plurality" means at least two, such as two, three, etc., unless otherwise expressly and specifically limited.

In the description of this specification, reference to the terms "one embodiment," "some embodiments," "an example," "specific examples," or "some examples" or the like means that specific features are described in connection with the embodiment or example. , structures, materials or features are included in at least one embodiment or example of the present application. In this specification, the schematic expressions of the above terms are not necessarily directed to the same embodiment or example. Furthermore, the specific features, structures, materials or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, those skilled in the art may combine and combine different embodiments or examples and features of different embodiments or examples described in this specification unless they are inconsistent with each other.

Although the embodiments of the present application have been shown and described above, it can be understood that the above-mentioned embodiments are illustrative and should not be construed as limitations of the present application. Those of ordinary skill in the art can make modifications to the above-mentioned embodiments within the scope of the present application. The embodiments are subject to changes, modifications, substitutions and variations.

Claims (10)

1. An animal tissue sampling device, characterized by including a puncture rod (3) and a sampling mechanism (2), wherein, The puncture rod (3) is a hollow structure, and the sampling mechanism (2) is provided on the puncture rod (3). The sampling mechanism (2) includes a sampling window (21) and a cutting assembly (23), wherein, The sampling window (21) is opened on the puncture rod (3), and the cutting assembly (23) penetrates and is movably arranged inside the sampling window (21). The cutting assembly (23) includes a cutting rod (23). 231), longitudinal cutting teeth (232) and radial cutting teeth (233), wherein, The cutting rod (231) is a hollow structure, the cutting rod (231) is movably arranged inside the puncture rod (3), and the radial cutting teeth (233) are symmetrically arranged on the cutting rod (231) On both sides of the annular surface, the longitudinal cutting teeth (232) are arranged on both sides of the end side of the cutting rod (231), and the radial cutting teeth (233) are in contact with the longitudinal cutting teeth (232). ) are connected end to end to form a cutting window (235), and the cutting window (235) and the sampling window (21) correspond to each other. 2. The animal tissue sampling equipment according to claim 1, characterized in that an anti-teeth loss (234) is provided on the inside of the radial cutting teeth (233), and the anti-teeth loss (234) is in conjunction with the radial cutting tooth (233). The included angle of the cutting teeth (233) is greater than 90°, and the tooth stripping prevention (234) is located inside the cutting window (235). 3. The animal tissue sampling device according to claim 1, characterized in that the sampling window (21) is provided with cutting edges (32) on both sides along the axial direction of the puncture rod (3), and the cutting edges (32) ) is a raised streamlined structure. 4. The animal tissue sampling equipment according to claim 1, characterized in that the puncture rod (3) is provided with a sampling depth scale (31), and the puncture end of the puncture rod (3) is provided with a puncture head. (1). The puncture head (1) is provided with a guide assembly (22) that drives the cutting rod (231) to elastically reset. The guide assembly (22) includes a guide chute (221), a spring (222) and Guide column (223), where, The guide chute (221) is provided inside the puncture head (1), the guide post (223) is slidably provided inside the guide chute (221), and the two ends of the spring (222) are respectively connected with the guide chute (221). The bottom of 221) is connected to one end of the guide column (223), the other end of the guide column (223) is provided with a polygonal chuck, and one end of the cutting rod (231) is provided with a polygonal chuck that matches the polygonal chuck. Polygonal card slot. 5. The animal tissue sampling equipment according to claim 1, characterized in that a sample recovery mechanism (5) is provided at one end of the cutting rod (231), and the sample recovery mechanism (5) includes a sample rod (51 ) and the pull handle (53), where, The sample rod (51) is a hollow structure, one end of the sample rod (51) is connected to the cutting rod (231), the sample rod (51) is disposed inside the puncture rod (3), and the pulling rod (51) is disposed inside the puncture rod (3). The handle (53) is provided at the other end of the sample rod (51). 6. The animal tissue sampling equipment according to claim 5, characterized in that a tissue fluid extraction mechanism (6) is provided inside the sample rod (51), and the tissue fluid extraction mechanism (6) includes a barrier filter ( 61), storage chamber (62) and suction pipe (64), wherein, The storage chamber (62) is disposed inside the sample rod (51), the partition filter (61) is disposed between the cutting rod (231) and the storage chamber (62), and the storage chamber (62) It is connected to the cutting rod (231) through the partition filter screen (61), one end of the suction pipe (64) is connected to the storage chamber (62), and the other end of the suction pipe (64) penetrates the sample rod ( 51). 7. The animal tissue sampling equipment according to claim 6, characterized in that the suction tube (64) is provided with a sealing seat (63), and the sealing seat (63) is arranged on the sample rod (51) Inside, a plug (52) is provided at the connection between the pull handle (53) and the sample rod (51), and the suction pipe (64) penetrates the plug (52). 8. The animal tissue sampling equipment according to claim 5, characterized in that a limited propulsion mechanism (4) is provided outside the puncture rod (3), and the limited propulsion mechanism (4) includes a fixed seat (41) , piston plate (42) and hydraulic groove (43), among which, The fixed seat (41) is sleeved on the outside of the puncture rod (3) and the sample rod (51). The hydraulic groove (43) is opened on the inner wall of the fixed seat (41). The puncture rod (3) faces away from One end of the puncture end is slidably disposed in the hydraulic groove (43), and the piston piece (42) is disposed on an end of the puncture rod (3) away from the puncture end. 9. The animal tissue sampling equipment according to claim 8, characterized in that a sealing sliding sleeve (45) is provided between the sample rod (51) and the fixed seat (41), and the sealing sliding sleeve (45) Set on the sample rod (51); A hydraulic joint (44) is provided through the fixed seat (41), and the hydraulic joint (44) is connected with the hydraulic tank (43). 10. The animal tissue sampling device according to claim 1, characterized in that the edge portion of the sampling window (21) is provided with sampling window cutting teeth (24).