CN116762816B - A herbicidal composition and its application - Google Patents

Abstract

The invention belongs to the field of pesticides, and particularly relates to a weeding composition and application thereof. The weeding composition comprises an active ingredient A and an active ingredient B in herbicidally effective amounts, wherein the active ingredient A is

Description

Weeding composition and application thereof

Technical Field

The invention belongs to the field of pesticides, and particularly relates to a weeding composition and application thereof.

Background

Chemical weeding is the most economical and effective means in farmland weed control, but long-term continuous high-dosage chemical herbicide with single variety or single action mode is easy to cause problems of weed resistance, resistance evolution and the like. The reasonable compounding or compounding of the herbicide compound has the advantages of expanding the weed spectrum, improving the preventing and killing effect, delaying the occurrence and development of weed resistance and drug resistance, and the like, is one of the most effective methods for solving the problems, and still needs to develop a herbicide composition variety with high safety, broad herbicide spectrum, capability of generating synergistic effect and solving the problem of resistant weeds in production.

Disclosure of Invention

In order to solve the problems in the prior art, the invention provides a weeding composition and application thereof. The composition can effectively prevent and remove various weeds in corn and soybean strip intercropped fields, has high safety and good selectivity to crops, and has the characteristics of expanding weed control spectrum, reducing application amount, generating synergistic effect, solving resistant weeds and the like.

A herbicidal composition comprising a herbicidally effective amount of an active ingredient A and an active ingredient B, wherein the active ingredient A isThe active ingredient B is selected from one or more than two of penoxsulam (CAS: 447399-55-5), acetochlor (CAS: 34256-82-1), butachlor (CAS: 23184-66-9), metolachlor (CAS: 86763-47-5), metolachlor (CAS: 87392-12-9), pendimethalin (CAS: 40487-42-1) and metribuzin (CAS: 21087-64-9).

When the active ingredient B is metazachlor, the weight ratio of A to B in the weeding composition is 4.5:1-15:1, preferably 5:1-10:1, and more preferably 5.5:1-9:1;

when the active ingredients B are acetochlor, butachlor, metolachlor and pendimethalin, the weight ratio of A to B in the weeding composition is 0.75:1-10:1, preferably 1:1-5:1, more preferably 1.5:1-3:1;

When the active ingredient B is metolachlor, the weight ratio of A to B in the weeding composition is 1:10-10:1, preferably 1:5-5:1, and more preferably 1:3-1:1;

When the active ingredient B is metribuzin, the weight ratio of A to B in the weeding composition is 1.8:1-10:1, preferably 2:1-5:1, and more preferably 2:1-4:1.

The mass percentage of A and B in the weeding composition accounts for 1-95% of the total amount, preferably 10-80%.

The herbicidal composition further comprises conventional adjuvants including carriers and/or surfactants.

The term "carrier" as used herein means an organic or inorganic, natural or synthetic substance. They facilitate the application of the active ingredient, which carriers are generally inert and must be agriculturally acceptable, in particular by the treated plants. The carrier may be solid, such as clay, natural or synthetic silicate, silica, resin, wax, solid fertilizer, etc., or liquid, such as water, alcohols, ketones, petroleum fractions, aromatic or waxy hydrocarbons, chlorinated hydrocarbons, liquefied gases, etc.

Surfactants may include emulsifiers, dispersants or wetting agents, which may be ionic or nonionic. Examples which may be mentioned are salts of polyacrylic acid, lignosulfonates, salts of phenolsulfonic acid or naphthalenesulfonic acid, polymers of ethylene oxide with aliphatic alcohols or with aliphatic amines with substituted phenols, in particular alkylphenols or arylphenols, sulfosuccinates, taurine derivatives, in particular taurates, and phosphates of alcohols or of polyethylated phenols, alkylsulfonates, alkylaryl sulfonates, alkyl sulfates, lauryl ether sulfates, fatty alcohol sulfates, and also sulfated hexadecyl-, heptadeca-and octadecanols and sulfated fatty alcohol glycol ethers, furthermore condensates of naphthalene or naphthalenesulfonic acid with phenol and formaldehyde, polyoxyethylene octylphenyl ether, ethoxylated isooctylphenols, octylphenols or nonylphenols, alkylphenyl polyglycol ethers, tributylphenyl polyglycol ethers, tristearylphenyl polyglycol ethers, alkylaryl polyether alcohols, alcohol and fatty alcohol/ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, lauryl alcohol polyglycol ethers, sorbitol esters, lignin sulfite waste solutions, and also proteins, polysaccharides (e.g. methylcellulose), polyvinyl alcohol, hydrophobically modified polyvinyl pyrrolidone, polyvinyl alcohol carboxylate, polyvinyl pyrrolidone, and copolymers thereof. At least one surfactant is required to be present to facilitate the dispersion of the active ingredients in water and to enable them to be applied correctly to the plants.

The above-described compositions may also contain various other components such as protective colloids, binders, thickeners, thixotropic agents, penetrating agents, stabilizers, chelating agents, dyes, colorants and polymers.

The herbicidal composition further comprises at least one safener, preferably one or more of bisbenzoxazole acid (CAS: 163520-33-0), cyprosulfamide (CAS: 221667-31-8), pyraclonil (CAS: 135590-91-9), cloquintocet-mexyl (CAS: 99607-70-2), gibberellic acid (CAS: 7-06-5), furilazole (CAS: 121776-33-8), metcamifen (CAS: 129531-12-0).

The compositions of the present invention may be diluted by the user prior to use or used directly. The preparation can be prepared by common processing method, namely, mixing the active substance with liquid solvent or solid carrier, and adding one or more surfactants such as dispersing agent, stabilizer, wetting agent, adhesive, defoamer, etc.

The specific preparation of the weeding composition is dispersible oil suspending agent, water suspending agent, suspending emulsion, wettable powder, emulsifiable concentrate, water dispersible granule (dry suspending agent), water emulsion and microemulsion.

Briefly, the compositions of the present invention can be mixed with solid and liquid additives conventionally used in prior art formulations. The amount of the active ingredient used varies with the external conditions such as temperature, humidity, the nature of the herbicide used, and the like. It may have a large variation, for example between 0.001 and 1.0kg/ha, or more, of active substance, but preferably between 0.005 and 750g/ha, in particular between 0.005 and 500 g/ha.

In the context of the present specification, if the abbreviated form of the generic name of the active compound is used, all customary derivatives, such as esters and salts, as well as isomers, in particular optical isomers, in particular one or more commercially available forms, are included in each case. If the generic name denotes esters or salts, all other customary derivatives are also included in each case, such as other esters and salts, free acids and neutral compounds, as well as isomers, in particular optical isomers, in particular one or more commercially available forms. The chemical name given to a compound means at least one compound covered by a common name, generally the preferred compound. In the case of sulfonamides such as sulfonylureas, salts also include salts formed by the exchange of cations with hydrogen atoms in the sulfonamide group. For example, 2-methyl 4-chloro derivatives include, but are not limited to, 2-methyl 4-chloro sodium salt, potassium salt, dimethyl ammonium salt, isopropyl amine salt, etc., and 2-methyl 4-chloro methyl ester, ethyl ester, isooctyl ester, ethyl thioester, etc., 2,4-D derivatives include, but are not limited to, 2,4-D salts such as sodium salt, potassium salt, dimethyl ammonium salt, triethanolammonium salt, isopropyl amine salt, choline, etc., and 2,4-D esters such as methyl ester, ethyl ester, butyl ester, isooctyl ester, etc.

The invention also provides a use of the herbicidal composition for controlling weeds and a method for controlling unwanted plant growth comprising applying the herbicidal composition to plants, plant parts, plant seeds or areas of plant growth.

In addition, the compositions of the invention can be applied by spraying onto the foliage of the plants to be treated, i.e. onto weeds, in particular onto surfaces which are infested or susceptible to infestation by weeds.

When the herbicidal composition of the present invention is applied, unexpected synergistic effects are obtained, and herbicidal activity is more remarkable than the sum of the expected activities using individual herbicides, and the activity of individual herbicides. The synergistic effect is manifested by a reduced application rate, a broader weed control spectrum, a faster and more durable herbicidal action, which are desirable in the practice of weed control. These new compositions are significantly superior to existing herbicides in terms of the characteristics described, achieving reduced use and being more environmentally friendly.

The synergistic weeding composition provided by the invention also has the following advantages:

(1) The composition of the invention is environment-friendly and is easy to degrade in the environment.

(2) The weeding composition disclosed by the invention is low in cost and convenient to use, and has great economic and social benefits in popularization and application.

All patents, patent applications, and publications mentioned or cited herein are hereby incorporated by reference in their entirety to the same extent as if each individual publication was specifically and individually indicated to be incorporated by reference.

Detailed Description

The following examples are not intended to limit the invention but are merely illustrative of how the invention may be practiced. For certain weeds, these examples showed particularly significant effectiveness. Examples are as follows:

A) Examples

Azol (36+6) aqueous suspension

36% Of A+6% of metazachlor+5% of polycarboxylate dispersant+3% of block polyether dispersant+2% of fatty alcohol polyoxyethylene ether+0.08% of xanthan gum+3% of ethylene glycol+0.1% of defoamer and deionized water

A+acetochlor (40+20) emulsifiable concentrate

40% Of A+20% of acetochlor+4.5% of calcium dodecyl benzene sulfonate+4% of cardanol polyoxyethylene ether+2% of block polyether emulsifier+15% of benzyl alcohol+180# solvent oil

A+butachlor (40+20) emulsifiable concentrate

40% Of A+20% of butachlor+5% of calcium dodecyl benzene sulfonate+5% of cardanol polyoxyethylene the ether, 3 percent of block polyether emulsifier, 15 percent of benzyl alcohol and 180# solvent oil are complemented

A+iprovalicarb (15+45) emulsifiable concentrate

15% Of A+45% of metolachlor, 5% of calcium dodecyl benzene sulfonate, 8% of cardanol polyoxyethylene ether, 3% of block polyether emulsifier and 180# solvent oil are supplemented

A+Mesona-concentrate (40+20) emulsifiable concentrate

The composition is prepared from 40% of A+20% of refined metolachlor, 5% of calcium dodecyl benzene sulfonate, 6% of cardanol polyoxyethylene ether, 1.6% of block polyether emulsifier, 15% of benzyl alcohol and 180# solvent oil

A+Dimevalonate (30+20) aqueous suspension

30% Of A+20% of pendimethalin+4% of polycarboxylate dispersant+2% of block polyether dispersant+3% of fatty alcohol polyoxyethylene ether+0.06% of xanthan gum+3% of ethylene glycol+1% of fumed silica+0.1% of defoamer and deionized water

A+oxaziclomefone (34+16) aqueous suspension

34% Of A+16% of metribuzin+4% of polycarboxylate dispersant+2% of block polyether dispersant+3% of fatty alcohol polyoxyethylene ether+0.06% of xanthan gum+3% of ethylene glycol+0.1% of defoamer and deionized water

The emulsifiable concentrate processing equipment comprises a mixing kettle, a storage tank and the like.

And (3) the processing process of the emulsifiable concentrate comprises the steps of putting all materials into a mixing kettle, stirring and mixing until all materials are completely dissolved, and transferring to a storage tank for filling after the materials are tested to be qualified.

The processing equipment of the water suspending agent comprises a mixing kettle, a colloid mill, a sand mill, a shearing machine and the like.

The processing process of the water suspending agent comprises the steps of putting all materials into a mixing kettle, stirring and mixing, then, feeding the materials into a colloid mill, performing three-stage sanding by a sand mill, finally, shearing uniformly in a shearing machine, and transferring the materials to a storage tank for filling after the test is qualified.

B) Test of efficacy

Soil sealing treatment:

1) Test conditions

1.1 Conditions of culture)

The method is carried out in a controllable sunlight greenhouse, the temperature is 20-30 ℃, natural illumination is carried out, and the relative humidity is 57-72%.

The soil type is loam, the organic matter content is 1.63%, the pH=7.1, the alkaline hydrolysis nitrogen content is 84.3mg/kg, the quick-acting phosphorus content is 38.5mg/kg, and the quick-acting potassium content is 82.1mg/kg. The test soil was quantitatively loaded to 3/4 of the pot, and then irrigated from the bottom of the pot to completely wet the soil to a saturated state. The weed seeds to be tested are subjected to germination accelerating treatment until the weed seeds are exposed to white, then uniformly and quantitatively broadcast on the surface, and soil is covered by 0.5-1cm according to the size of the seeds, and the weed seeds are sowed for later use for 72 hours.

1.2 Equipment and instruments

GA10 model ten thousandth electronic balance (germany), ZDR2000 intelligent data recorder (zengzhou ze instruments limited), SPX intelligent biochemical incubator (Ningbo jiang south instrumentation factory), pipettor, etc.

2) Test design

2.1 Reagents) and

2.1.1 Pharmaceutical composition for testing)

Desired active ingredient a the active ingredient B required for the synthesis (¹H NMR(500MHz,DMSO-d₆)δ7.81(d,J＝2.0Hz,1H),7.48–7.55(m,1H),7.41(d,J＝8.5Hz,1H),4.72(s,2H),4.07(s,2H),1.16(s,6H).); is purchased from the reagent company with reference to patent US 1105357. The raw materials are all diluted by using acetone as solvent and 0.1% of emulsifier Tween-80 aqueous solution, and the diluted materials are diluted at present.

2.2 Test treatment)

2.2.1 A) and dose setting

In determining the proportion or content of each component of the A and the active ingredient B, the main purpose of the formulation should be considered according to the action characteristics of the two medicaments, the toxicity and other measures. The study was based on the preliminary pre-test, and the single use and the mixed use of A, B active ingredients are shown in the table. Water without agent, with the same solvent and emulsifier was used as a blank.

2.2.2 Repetition of test)

Each treatment was repeated 4 times, 3 pots each time, 20 weed seeds per pot were sown.

2) Test method

Irrigation was carried out before treatment, and a 1-2cm aqueous layer was maintained. And (3) taking quantitative liquid medicine by using a liquid transfer device, respectively carrying out irrigation treatment from low dose to high dose according to test design, repeating the treatment for 4 times, transferring the treated liquid medicine into a greenhouse for conventional culture, and keeping a water layer of 1-2cm all the time during the test.

3) Data investigation and statistical analysis

3.1 Method of investigation)

The entire seedlings of surviving weeds were cut off along the soil surface with a blade by an absolute number survey method, and the fresh weight of weeds was weighed with an analytical balance. For weeds that have died, the fresh weight is zero.

3.2 Time and number of surveys)

The investigation was performed 21 days after the treatment, 1 total.

3.3 Data statistical analysis)

Calculating the theoretical fresh weight inhibition rate (E0=X+Y-X X Y/100) of each treatment mixed combination by Gowing method, then comparing with the actual measurement inhibition rate (E), evaluating the combined action type of the mixed combination of the two to weeds, and when the E-E0 value is more than 10% and is synergistic, less than-10% is antagonistic and is addition between-10% and 10%. And determining the optimal proportion according to the actual control effect, the characteristics of herbicide, the balance of the formula and other factors. Wherein X is the fresh weight inhibition rate when the dosage of the active ingredient A is P, and Y is the fresh weight inhibition rate when the dosage of the active ingredient B is Q.

Table 1A evaluation of actual control and combined action of Pyricularia sulfone and Pyricularia sulfone on barnyard grass

Table 2A evaluation of actual control and combined action of acetochlor on barnyard grass

TABLE 3 evaluation of actual control and combined action of butachlor on barnyard grass by A compounding

Table 4A evaluation of actual control and combined action of metolachlor on barnyard grass

Table 5A evaluation of actual control and combined action of metolachlor on barnyard grass

Table 6A evaluation of actual control and combined action of Dimethoprene on barnyard grass

Table 7A evaluation of actual control and combined action of oxaziclomefone on barnyard grass

C) Demonstration of field

The herbicidal compositions prepared in examples 1 to 7 were used for the test of the effect of weeds in corn and soybean strip-type intercropped fields, and weeds occurring in the fields were mainly crabgrass, barnyard grass, gooseberry, purslane, etc.

The test method comprises the following steps:

Soil treatment (S) is carried out by adding 45 kg/667 m2 water into manual sprayer before germination of weeds, and uniformly spraying on soil surface.

The specific test agents and dosages are detailed in Table 8, with a cell area of 20 square meters and each treatment repeated 3 times. The investigation and control effects 20 days after the application are shown in Table 8.

Exemplary field effects of the formulated compositions described in Table 8

Through a large number of experiments and researches, the composition is unexpectedly found that the composition is used for preventing and killing main grassy weeds, broadleaf weeds, sedge weeds and the like, has a surprising and unexpected synergistic effect, is more remarkable in the synergistic effect under a low dosage, can reduce the dosage, reduces the pollution to the environment, reduces the agricultural cost through reasonable compounding, and has good application prospect. Meanwhile, the herbicide mixture has good selectivity and excellent synergistic effect on plants such as wheat fields, corn fields, paddy fields, peanuts, sugarcane, sorghum, millet, potatoes, rape, soybeans, cotton, vegetables, bluegrass, festuca arundinacea, zoysia japonica and the like through tests, and can be developed into herbicide mixtures with wide market value.

Claims (12)

1. A herbicidal composition comprising a herbicidally effective amount of an active ingredient A and an active ingredient B, wherein the active ingredient A isThe active component B is selected from one of the following compounds of penoxsulam, acetochlor, butachlor, metolachlor, mefenacet, pendimethalin and metribuzin,

When the active ingredient B is metazachlor, the weight ratio of A to B in the weeding composition is 5.5:1-9:1;

When the active ingredient B is acetochlor, butachlor, metolachlor, and pendimethalin, the weight ratio of A to B in the weeding composition is 1.5:1-3:1;

When the active ingredient B is metolachlor, the weight ratio of A to B in the weeding composition is 1:3-1:1;

When the active ingredient B is metribuzin, the weight ratio of A to B in the weeding composition is 2:1-4:1.

2. The herbicidal composition according to claim 1, wherein the mass percentage of a and B in the herbicidal composition is 1 to 95% of the total amount.

3. The herbicidal composition according to claim 2, wherein the mass percentage of a and B in the herbicidal composition is 10 to 80% of the total amount.

4. The herbicidal composition according to claim 1, wherein, the weeding composition also comprises conventional auxiliary agents.

5. The herbicidal composition of claim 4 wherein the conventional adjuvants comprise carriers and/or surfactants.

6. The herbicidal composition of claim 1 wherein the herbicidal composition further comprises at least one safener.

7. The herbicidal composition of claim 6 wherein the safener is selected from one or more of bisbenzoxazole acid, cyprosulfamide, pyraclostrobin, cloquintocet-mexyl, gibberellic acid, furilazole, metcamifen.

8. The herbicidal composition of claim 1 wherein the specific formulation of the herbicidal composition is a dispersible oil suspension, an aqueous suspension, a suspoemulsion, a wettable powder, an emulsifiable concentrate, a water dispersible granule, an aqueous emulsion or a microemulsion.

9. Use of a herbicidal composition according to any of claims 1 to 8 for controlling weeds.

10. Use of a herbicidal composition according to any one of claims 1 to 8 for controlling weeds in corn and soybean fields.

11. A method of controlling unwanted plant growth comprising applying the herbicidal composition of any one of claims 1 to 8 to a plant, plant seed or area of plant growth.

12. The method of claim 11, wherein the unwanted plant is corn, soybean strip intercropping field weeds.