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CN116650566A - Four-black-bone arthralgia-relieving traditional Chinese medicine composition and preparation method and application method thereof - Google Patents

Four-black-bone arthralgia-relieving traditional Chinese medicine composition and preparation method and application method thereof Download PDF

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CN116650566A
CN116650566A CN202310763168.7A CN202310763168A CN116650566A CN 116650566 A CN116650566 A CN 116650566A CN 202310763168 A CN202310763168 A CN 202310763168A CN 116650566 A CN116650566 A CN 116650566A
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aconitum
chinese medicine
medicine composition
traditional chinese
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覃伟
周刚
龙红琼
尤庆峰
谢东
张万桂
杨培培
袁良辰
王智超
王思洋
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Yichang traditional chinese medicine hospital
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Abstract

本发明提供了一种四乌散痹中药组合物,其包括230‑250份川乌、230‑250份草乌、180‑220份乌梢蛇、580‑620份威灵仙、280‑300份乌梅、580‑620份鸡血藤、220‑260份木瓜、580‑620份青风藤、4500‑5000份白酒,其中白酒酒精度为52‑60°。本发明同时还提供了该组合物的制备方法和使用方法。本发明副作用少、小,非常适合制作成散、膏贴、洗剂、酊剂药酒剂等多种剂型推广使用,丰富了痹症的中医治疗方药选择。The invention provides a Siwu Sanbi traditional Chinese medicine composition, which comprises 230-250 parts of Aconitum aconitum, 230-250 parts of Aconitum aconiti, 180-220 parts of black snake, 580-620 parts of Clematis, 280-300 parts of Black plum, 580-620 parts of Mildew Spathifolia, 220-260 parts of Papaya, 580-620 parts of Qingfengteng, 4500-5000 parts of white wine, of which the alcohol content of white wine is 52-60°. The invention also provides the preparation method and application method of the composition. The invention has few and small side effects, is very suitable for being made into powder, plaster, lotion, tincture, medicine liquor and other dosage forms for popularization and use, and enriches the selection of traditional Chinese medicine prescriptions for treating arthralgia.

Description

一种四乌散痹中药组合物及其制备方法和使用方法A Siwu Sanbi traditional Chinese medicine composition and its preparation method and application method

技术领域technical field

本发明涉及中药组合物技术领域,尤其涉及一种四乌散痹中药组合物及其制备方法和使用方法。The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition of Siwu Sanbi and its preparation method and application method.

背景技术Background technique

痹症:痹症是指人体机表、经络因感受风、寒、湿、热等引起的以肢体关节及肌肉酸痛、麻木、重着、屈伸不利,甚或关节肿大灼热等为主症的一类病证。临床上有渐进性或反复发作性的特点。主要病机是气血痹阻不通,筋脉关节失于濡养所致。Arthralgia: Arthralgia refers to a class of diseases in which the body surface and meridians are affected by wind, cold, dampness, heat, etc. The main symptoms are pain, numbness, heaviness, difficulty in flexion and extension of limb joints and muscles, or even swelling and burning of joints. certificate. Clinically there are progressive or recurrent features. The main pathogenesis is that qi and blood numbness is blocked, and the tendons and arteries are lost in moistening and nourishing.

痹症与外感风寒湿热之邪和人体正气不足有关。风寒湿等邪气,在人体卫气虚弱时容易侵入人体而致病。汗出当风、坐卧湿地、涉水冒雨等,均可使风寒湿等邪气侵入机体经络,留于关节,导致经脉气血闭阻不通,不通则痛,正如《素问·痹论》所说:“风寒湿三气杂至,合而为痹。”根据感受邪气的相对轻重,常分为行痹(风痹)、痛痹(寒痹)、着痹(湿痹)。若素体阳盛或阴虚火旺,复感风寒湿邪,邪从热化或感受热邪,留注关节,则为热痹。总之,风寒湿热之邪侵入机体,痹阻关节肌肉筋络,导致气血闭阻不通,气滞血瘀,痹阻经络,筋脉关节失于濡养产生本病。目前,中药治疗痹症治疗方药不丰富。Arthralgia is related to the heresy of exogenous wind-cold, damp-heat and the deficiency of human righteousness. Evil qi such as wind, cold and damp can easily invade the human body and cause disease when the human body's defensive qi is weak. Sweating against the wind, sitting and lying on wet ground, wading in the rain, etc., can cause wind, cold and dampness and other pathogenic factors to invade the meridians of the body and stay in the joints, resulting in blockage of qi and blood in the meridians. It is said: "The three qi of wind, cold and damp are mixed together, and they combine to form numbness." According to the relative severity of the perceived evil energy, it is often divided into xingbi (wind numbness), painful numbness (cold numbness), and dampness numbness (dampness numbness). If the body is full of yang or yin-deficiency and fire-exuberant, and you feel wind-cold-damp evil again, and the evil turns from heat or you feel heat evil and stay in the joints, then it is heat arthralgia. In a word, wind-cold, damp-heat pathogens invade the body, numb the joints, muscles and tendons, resulting in occlusion of qi and blood, stagnation of qi and blood stasis, numbness of the meridians, loss of tendons and arteries and joints, leading to primary disease. At present, there are not many prescriptions for the treatment of arthralgia by traditional Chinese medicine.

发明内容Contents of the invention

针对现有技术中所存在的不足,本发明提供了一种四乌散痹中药组合物及其制备方法和使用方法,丰富了中医治疗痹症的方药选择。Aiming at the deficiencies in the prior art, the invention provides a Siwu Sanbi traditional Chinese medicine composition and its preparation method and use method, which enriches the selection of prescriptions for treating Bi syndrome in traditional Chinese medicine.

根据本发明的实施例,一种四乌散痹中药组合物,按重量计,包括230-250份川乌、230-250份草乌、180-220份乌梢蛇、580-620份威灵仙、280-300份乌梅、580-620份鸡血藤、220-260份木瓜、580-620份青风藤、4500-5000份白酒,其中白酒酒精度为52-60°。According to an embodiment of the present invention, a Siwu Sanbi traditional Chinese medicine composition comprises 230-250 parts of Aconitum aconitum, 230-250 parts of Aconitum aconitum, 180-220 parts of black snake, 580-620 parts of Weiling Xian, 280-300 parts of ebony plums, 580-620 parts of Caulis Spatholobus, 220-260 parts of papaya, 580-620 parts of Qingfengteng, 4500-5000 parts of white wine, wherein the alcohol content of white wine is 52-60 °.

根据另一实施例,提供了上述组合物的制备方法,将川乌、草乌、乌梢蛇、威灵仙、乌梅、鸡血藤、木瓜、青风藤加入白酒中浸泡160-200日。According to another embodiment, a preparation method of the above-mentioned composition is provided. Aconitum aconitum, Aconitum aconitum, Snake, Clematis, Ume, Spatholobus, papaya, and Qingfengteng are added to white wine and soaked for 160-200 days.

根据另一实施例,提供了上述四乌散痹中药组合物的使用方法,过滤得液体,所得液体导入患部。According to another embodiment, a method for using the above-mentioned Siwu Sanbi traditional Chinese medicine composition is provided, the liquid is filtered, and the obtained liquid is introduced into the affected part.

进一步地,采用推拿法导入患部,推拿时间15-20min。Further, the massage method is used to introduce into the affected area, and the massage time is 15-20 minutes.

进一步地,采用超声导入仪导入患部,超声时间10-15min。Further, an ultrasonic introduction instrument is used to introduce into the affected part, and the ultrasonic time is 10-15 minutes.

根据另一实施例,提供了另一种四乌散痹中药组合物,按重量计,包括230-250份川乌、230-250份草乌、180-220份乌梢蛇、580-620份威灵仙、280-300份乌梅、580-620份鸡血藤、220-260份木瓜、580-620份青风藤和4500-5000份水。According to another embodiment, another Siwu Sanbi traditional Chinese medicine composition is provided, including 230-250 parts of Aconitum aconitum, 230-250 parts of Aconitum aconitum, 180-220 parts of Aconitum aconitiformis, 580-620 parts of Clematis, 280-300 parts of black plum, 580-620 parts of Milletah, 220-260 parts of papaya, 580-620 parts of Qingfengteng and 4500-5000 parts of water.

根据另一实施例,提供了上述组合物的制备方法,将川乌、草乌、乌梢蛇、威灵仙、乌梅、鸡血藤、木瓜、青风藤加入水中煎20-30min。According to another embodiment, a preparation method of the above-mentioned composition is provided. Aconitum aconitum, Aconitum aconitum, Snake, Clematis clematis, Ume, Millae Spatholobus, papaya, and Qingfengteng are added to water and decocted for 20-30 minutes.

根据另一实施例,提供了上述四乌散痹中药组合物的使用方法,过滤得液体,所得液体导入患部。According to another embodiment, a method for using the above-mentioned Siwu Sanbi traditional Chinese medicine composition is provided, the liquid is filtered, and the obtained liquid is introduced into the affected part.

进一步地,滤液浸润敷料后将敷料贴敷在患处热敷30-40min。Further, after the filtrate infiltrates the dressing, apply the dressing to the affected area and apply heat for 30-40 minutes.

进一步地,将患处浸泡于滤液中,浸泡15-25min。Further, soak the affected part in the filtrate for 15-25 minutes.

相比于现有技术,本发明具有如下有益效果:Compared with the prior art, the present invention has the following beneficial effects:

本发明组合物具有祛风除湿、解表散寒,活血化瘀,蠲痹通络止痛等功效。对风寒阻络型,寒凝静脉,淤血阻络,寒湿凝滞,等多型关节痹症均有良好的功效;能改善患者颈,肩,肘,腕,髋,膝等多处关节得骨、筋、肉的功能状态,显著的改善临床麻木、僵硬、疼痛,发冷等症状;本方副作用少、小,非常适合制作成散、膏贴、洗剂、酊剂、药酒剂等多种剂型推广使用。The composition of the present invention has the effects of dispelling wind and dampness, relieving exterior syndrome and dispelling cold, promoting blood circulation and removing blood stasis, dredging numbness, dredging collaterals, relieving pain and the like. It has a good effect on wind-cold blocking collaterals, cold coagulation veins, blood stasis blocking collaterals, cold-damp stagnation, and other types of arthralgia; it can improve patients' neck, shoulders, elbows, wrists, hips, knees and other joints. Functional status of tendons and muscles, significantly improving clinical symptoms such as numbness, stiffness, pain, and chills; this prescription has few side effects and is very suitable for the promotion of various dosage forms such as powder, plaster, lotion, tincture, and medicinal liquor use.

具体实施方式Detailed ways

下面结合实施例对本发明中的技术方案进一步说明。The technical solution in the present invention will be further described below in conjunction with the embodiments.

实施例1Example 1

本实施例提供了一种四乌散痹中药组合物,将230g川乌、230g草乌、180g乌梢蛇、580g威灵仙、280g乌梅、580g鸡血藤、220g木瓜、580g青风藤加入4500L白酒中(白酒酒精度为52°),静置浸泡200日。This embodiment provides a Siwu Sanbi traditional Chinese medicine composition, 230g Chuanwu, 230g Caowu, 180g Wushaoshe, 580g Clematis, 280g ebony, 580g Milletah, 220g papaya, 580g Qingfengteng In 4500L white wine (the alcohol content of the white wine is 52°), stand and soak for 200 days.

实施例2Example 2

本实施例提供了一种四乌散痹中药组合物,将240g川乌、240g草乌、200g乌梢蛇、600g威灵仙、290g乌梅、600g鸡血藤、240g木瓜、600g青风藤加入4800L白酒中(白酒酒精度为56°),静置浸泡180日。This embodiment provides a Siwu Sanbi traditional Chinese medicine composition, 240g Chuanwu, 240g Caowu, 200g Wushaoshe, 600g Clematis, 290g Ume, 600g Milletah, 240g papaya, 600g Qingfengteng In 4800L white wine (the alcohol content of the white wine is 56°), stand and soak for 180 days.

实施例3Example 3

本实施例提供了一种四乌散痹中药组合物,将250g川乌、250g草乌、220g乌梢蛇、620g威灵仙、300g乌梅、620g鸡血藤、260g木瓜、620g青风藤加入5000L白酒中(白酒酒精度为60°),静置浸泡160日。This embodiment provides a Siwu Sanbi traditional Chinese medicine composition, 250g Chuanwu, 250g Caowu, 220g Wushaoshe, 620g Clematis, 300g ebony, 620g Caulis Spatholobus, 260g papaya, 620g Qingfengteng In 5000L liquor (the alcohol content of liquor is 60°), stand and soak for 160 days.

实施例4Example 4

本实施例提供了一种四乌散痹中药组合物,与实施例1相比,不同在于如下:The present embodiment provides a Siwu Sanbi traditional Chinese medicine composition, compared with Example 1, the difference is as follows:

将白酒替换成水,浸泡替换为水煎20min。Replace white wine with water, and replace soaking with decoction for 20 minutes.

实施例5Example 5

本实施例提供了一种四乌散痹中药组合物,与实施例2相比,不同在于如下:The present embodiment provides a Siwu Sanbi traditional Chinese medicine composition, compared with Example 2, the difference is as follows:

将白酒替换成水,浸泡替换为水煎25min。Replace white wine with water, and replace soaking with decoction for 25 minutes.

实施例6Example 6

本实施例提供了一种四乌散痹中药组合物,与实施例3相比,不同在于如下:The present embodiment provides a Siwu Sanbi traditional Chinese medicine composition, compared with Example 3, the difference is as follows:

将白酒替换成水,浸泡替换为水煎30min。Replace white wine with water, and replace soaking with decoction for 30 minutes.

将上述实施例1-3提供的四乌散痹中药组合物过滤收集液体,取液体通过表1中下述方式进行处理:The Siwusanbi Chinese medicine composition provided by the above-mentioned embodiments 1-3 is filtered to collect the liquid, and the liquid is processed in the following manner in Table 1:

表1:Table 1:

注:每日2次,7日为一疗程。Note: 2 times a day, 7 days as a course of treatment.

将上述实施例4-6提供的四乌散痹中药组合物过滤收集液体,取液体通过表2中下述方式进行处理:The Siwusanbi Chinese medicine composition provided by the above-mentioned embodiments 4-6 is filtered to collect the liquid, and the liquid is processed in the following manner in Table 2:

表1:Table 1:

注:每日1次,7日为一疗程。Note: 1 time a day, 7 days as a course of treatment.

上述表1和表2中处理患者均为中医诊断为痹症,经过1疗程后,统计疗效如下:The treatment patients in the above table 1 and table 2 are all diagnosed as Arthralgia by traditional Chinese medicine. After 1 course of treatment, the statistical curative effect is as follows:

注:对照组方案:痹证患者行:推拿治疗、电针、艾灸、红光治疗,每日1次,7日为一疗程;Note: The plan of the control group: patients with Arthralgia Syndrome: massage therapy, electroacupuncture, moxibustion, red light therapy, once a day, 7 days as a course of treatment;

计算总有效率公式为:总有效率=(治愈+有效)/n×100%,其中,n为总患者数,Calculating the total effective rate formula is: total effective rate=(cure+effective)/n×100%, wherein, n is the total number of patients,

治愈:伤完全消失,对工作及生活无影响;Healing: the injury completely disappears, and has no effect on work and life;

有效:患者疼痛有明显减轻,神经损伤有明显改善,对工作及生活有一定影响;Effective: The patient's pain is significantly relieved, and the nerve damage is significantly improved, which has a certain impact on work and life;

无效:患者疼痛、神经损失均无改善,或加重,对工作及生活有严重影响。Invalid: The patient's pain and nerve loss did not improve, or aggravated, which had a serious impact on work and life.

最后说明的是,以上实施例仅用以说明本发明的技术方案而非限制,尽管参照较佳实施例对本发明进行了详细说明,本领域的普通技术人员应当理解,可以对本发明的技术方案进行修改或者等同替换,而不脱离本发明技术方案的宗旨和范围,其均应涵盖在本发明的权利要求范围当中。Finally, it is noted that the above embodiments are only used to illustrate the technical solutions of the present invention without limitation. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present invention can be carried out Modifications or equivalent replacements without departing from the spirit and scope of the technical solution of the present invention shall be covered by the claims of the present invention.

Claims (10)

1.一种四乌散痹中药组合物,按重量计,其特征在于,包括230-250份川乌、230-250份草乌、180-220份乌梢蛇、580-620份威灵仙、280-300份乌梅、580-620份鸡血藤、220-260份木瓜、580-620份青风藤、4500-5000份白酒,其中白酒酒精度为52-60°。1. A Siwu Sanbi Chinese medicine composition, by weight, is characterized in that it comprises 230-250 parts of Aconitum aconitum, 230-250 parts of Aconitum aconitum, 180-220 parts of black snake, 580-620 parts of Clematis , 280-300 parts of ebony plums, 580-620 parts of Caulis Spatholobus, 220-260 parts of papaya, 580-620 parts of Qingfengteng, 4500-5000 parts of white wine, wherein the alcohol content of white wine is 52-60 °. 2.如权利要求1所述的四乌散痹中药组合物的制备方法,其特征在于,将川乌、草乌、乌梢蛇、威灵仙、乌梅、鸡血藤、木瓜、青风藤加入白酒中浸泡160-200日。2. the preparation method of Siwu Sanbi Chinese medicine composition as claimed in claim 1, is characterized in that, with Aconitum aconitum, Aconitum aconitum, Snake of black tip, Clematis clematis, plum, Spatholobus Spatholobus, Fructus Chaenomelis, Radix Sinensis Add in white wine and soak for 160-200 days. 3.一种四乌散痹中药组合物,按重量计,其特征在于,包括230-250份川乌、230-250份草乌、180-220份乌梢蛇、580-620份威灵仙、280-300份乌梅、580-620份鸡血藤、220-260份木瓜、580-620份青风藤和4500-5000份水。3. A Siwu Sanbi traditional Chinese medicine composition is characterized in that, by weight, it comprises 230-250 parts of Aconitum aconitum, 230-250 parts of Aconitum aconitum, 180-220 parts of black snake, 580-620 parts of Clematis , 280-300 parts of ebony plum, 580-620 parts of Caulis Spatholobus, 220-260 parts of papaya, 580-620 parts of Qingfengteng and 4500-5000 parts of water. 4.如权利要求2所述的四乌散痹中药组合物的制备方法,其特征在于,将川乌、草乌、乌梢蛇、威灵仙、乌梅、鸡血藤、木瓜、青风藤加入水中煎20-30min。4. the preparation method of Siwusanbi Chinese medicine composition as claimed in claim 2 is characterized in that, with Aconitum aconitum, Aconitum aconitum, Snake snakehead, Clematis clematis, ebony plum, Spatholobus Spatholobus, Chinese papaya, Tengweed Add water and fry for 20-30min. 5.如权利要求1所述的四乌散痹中药组合物的使用方法,其特征在于,过滤得液体,所得液体导入患部。5. The method of using the Siwu Sanbi traditional Chinese medicine composition as claimed in claim 1, wherein the liquid is obtained by filtering, and the obtained liquid is introduced into the affected part. 6.如权利要求5所述的使用方法,其特征在于,采用推拿法导入患部,推拿时间15-20min。6. The method of use according to claim 5, characterized in that the massage method is used to introduce into the affected part, and the massage time is 15-20 minutes. 7.如权利要求5所述的使用方法,其特征在于,采用超声导入仪导入患部,超声时间10-15min。7. The method of use according to claim 5, characterized in that, the ultrasonic introduction instrument is used to introduce into the affected part, and the ultrasonic time is 10-15 minutes. 8.如权利要求3所述的四乌散痹中药组合物的使用方法,其特征在于,过滤得液体,所得液体导入患部。8. The method of using the Siwusanbi traditional Chinese medicine composition as claimed in claim 3, wherein the liquid is obtained by filtering, and the obtained liquid is introduced into the affected part. 9.如权利要求8所述的使用方法,其特征在于,滤液浸润敷料后将敷料贴敷在患处热敷30-40min。9. The method of use according to claim 8, characterized in that, after the filtrate infiltrates the dressing, the dressing is applied to the affected area for 30-40 minutes. 10.如权利要求8所述的使用方法,其特征在于,将患处浸泡于滤液中,浸泡15-25min。10. The method according to claim 8, characterized in that the affected part is soaked in the filtrate for 15-25min.
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