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CN116616790B - Cardiac risk assessment method, apparatus, computer device and storage medium - Google Patents

Cardiac risk assessment method, apparatus, computer device and storage medium Download PDF

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CN116616790B
CN116616790B CN202310907009.XA CN202310907009A CN116616790B CN 116616790 B CN116616790 B CN 116616790B CN 202310907009 A CN202310907009 A CN 202310907009A CN 116616790 B CN116616790 B CN 116616790B
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左能
黄庆玺
李小钦
龙文瑶
方红
刘文玉
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    • AHUMAN NECESSITIES
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Abstract

本申请涉及一种心脏风险评估方法、装置、计算机设备与存储介质,所述方法包括:获取与临床适应症相匹配的目标心电检测所对应的心电数据;所述临床适应症用于指示能否进行负荷运动心电检测;所述目标心电检测至少包括静息心电检测;按照所述目标心电检测对所述心电数据中QRS波群的高频成分进行分析得到相应参考特征;根据所述参考特征确定心脏风险评估等级与心脏风险类型;所述心脏风险评估等级作为对受测者进行分流的参考指标;所述心脏风险类型作为评估所述受测者的心脏可能存在的风险类型的参考指标。采用本方法能够通过无创方式提高心脏健康状况识别准确性。

This application relates to a cardiac risk assessment method, device, computer equipment and storage medium. The method includes: obtaining ECG data corresponding to target ECG detection that matches clinical indications; the clinical indications are used to indicate Whether stress exercise ECG detection can be performed; the target ECG detection at least includes resting ECG detection; and the high-frequency components of the QRS wave group in the ECG data are analyzed according to the target ECG detection to obtain the corresponding reference features. ; Determine the heart risk assessment level and heart risk type according to the reference characteristics; the heart risk assessment level is used as a reference index for shunting the subject; the heart risk type is used to evaluate the possible existence of the subject's heart Reference indicators for risk types. Using this method can improve the accuracy of identifying cardiac health status in a non-invasive way.

Description

心脏风险评估方法、装置、计算机设备与存储介质Cardiac risk assessment method, device, computer equipment and storage medium

技术领域Technical Field

本申请涉及心电数据处理技术领域,特别是涉及一种心脏风险评估方法、装置、计算机设备与存储介质。The present application relates to the technical field of electrocardiogram data processing, and in particular to a cardiac risk assessment method, apparatus, computer equipment and storage medium.

背景技术Background Art

目前,通常基于心电图(ECG)中表征心脏复极阶段的ST-T段数据来分析心脏活性相关信息,从而实现对心脏的风险评估,但是很多心脏潜在问题在ST-T段数据表现并无异常,由此存在心脏风险评估准确性低的问题,若需要更加准确地评估心脏风险从而更有效地识别心脏健康状况,则需要基于冠脉造影、心肌活检等有创方式来实现,而有创评估方式会对受测者的身体健康产生或多或少的影响。At present, cardiac activity-related information is usually analyzed based on the ST-T segment data that represents the cardiac repolarization phase in the electrocardiogram (ECG) to achieve cardiac risk assessment. However, many potential heart problems do not show any abnormalities in the ST-T segment data, resulting in low accuracy in cardiac risk assessment. If it is necessary to more accurately assess cardiac risk and thus more effectively identify heart health conditions, it needs to be achieved through invasive methods such as coronary angiography and myocardial biopsy. Invasive assessment methods will have more or less impact on the physical health of the subject.

发明内容Summary of the invention

基于此,有必要针对上述技术问题,提供一种能够通过无创方式提高心脏健康状况识别准确性的心脏风险评估方法、装置、计算机设备与存储介质。Based on this, it is necessary to provide a cardiac risk assessment method, device, computer equipment and storage medium that can improve the accuracy of identifying cardiac health status in a non-invasive manner to address the above technical problems.

一种心脏风险评估方法,所述方法包括:A method for assessing cardiac risk, the method comprising:

获取与临床适应症相匹配的目标心电检测所对应的心电数据;所述临床适应症用于指示能否进行负荷运动心电检测;所述目标心电检测至少包括静息心电检测;Acquire ECG data corresponding to a target ECG test that matches a clinical indication; the clinical indication is used to indicate whether a load exercise ECG test can be performed; the target ECG test at least includes a resting ECG test;

按照所述目标心电检测对所述心电数据中QRS波群的高频成分进行分析得到相应参考特征;Analyzing the high-frequency components of the QRS complex in the electrocardiogram data according to the target electrocardiogram detection to obtain corresponding reference features;

根据所述参考特征确定心脏风险评估等级与心脏风险类型;所述心脏风险评估等级作为对受测者进行分流的参考指标;所述心脏风险类型作为评估所述受测者的心脏可能存在的风险类型的参考指标。The cardiac risk assessment level and the cardiac risk type are determined based on the reference characteristics; the cardiac risk assessment level is used as a reference indicator for triaging the subject; and the cardiac risk type is used as a reference indicator for assessing the possible risk type of the subject's heart.

在其中一个实施例中,若所述目标心电检测仅包括静息心电检测,则所述心电数据包括所述受测者的年龄与静息心电信号,所述参考特征包括第一静息参考特征;所述按照所述目标心电检测对所述心电数据中QRS波群的高频成分进行分析得到相应参考特征,包括:In one embodiment, if the target ECG detection only includes resting ECG detection, the ECG data includes the age and resting ECG signal of the subject, and the reference feature includes a first resting reference feature; the high-frequency component of the QRS complex in the ECG data is analyzed according to the target ECG detection to obtain the corresponding reference feature, including:

分析所述静息心电信号中QRS波群的高频成分得到高频QRS包络曲线;Analyzing the high-frequency components of the QRS complex in the resting electrocardiogram signal to obtain a high-frequency QRS envelope curve;

根据所述高频QRS包络曲线与所述年龄确定第一静息参考特征;所述第一静息参考特征包括静息阳性导联数量、静息临界导联数量、第一目标导联数量与第二目标导联数量;所述第一目标导联数量是指相应高频形态指数大于或等于第一指数阈值的静息导联的数量;所述第二目标导联数量是指相应均方根电压小于或等于第一电压阈值的静息导联的数量。A first resting reference feature is determined according to the high-frequency QRS envelope curve and the age; the first resting reference feature includes the number of resting positive leads, the number of resting critical leads, the number of first target leads and the number of second target leads; the first target number of leads refers to the number of resting leads whose corresponding high-frequency morphology index is greater than or equal to the first index threshold; the second target number of leads refers to the number of resting leads whose corresponding root mean square voltage is less than or equal to the first voltage threshold.

在其中一个实施例中,所述参考特征还包括第二静息参考特征;所述按照所述目标心电检测对所述心电数据中QRS波群的高频成分进行分析得到相应参考特征,还包括:In one embodiment, the reference feature further includes a second resting reference feature; and the step of analyzing the high frequency components of the QRS complex in the ECG data according to the target ECG detection to obtain the corresponding reference feature further includes:

根据所述高频QRS包络曲线与所述年龄确定第二静息参考特征;所述第二静息参考特征包括所述静息阳性导联数量、所述静息临界导联数量与所述第一目标导联数量;Determining a second resting reference feature according to the high-frequency QRS envelope curve and the age; the second resting reference feature includes the number of resting positive leads, the number of resting critical leads and the first target lead number;

所述根据所述参考特征确定心脏风险评估等级与心脏风险类型,包括:The determining of the cardiac risk assessment level and the cardiac risk type according to the reference feature comprises:

根据所述第一静息参考特征确定第一风险评估等级;determining a first risk assessment level according to the first resting reference feature;

根据所述第二静息参考特征确定第二风险评估等级;determining a second risk assessment level according to the second resting reference feature;

根据所述第一风险评估等级与所述第二风险评估等级确定心脏风险评估等级与心脏风险类型。A cardiac risk assessment level and a cardiac risk type are determined according to the first risk assessment level and the second risk assessment level.

在其中一个实施例中,所述第一静息参考特征还包括目标高频形态指数与目标均方根电压;所述第二静息参考特征还包括所述目标高频形态指数;所述目标高频形态指数为各静息导联对应的高频形态指数中的最大值;所述目标均方根电压为各静息导联对应的均方根电压中的最小值。In one embodiment, the first resting reference feature also includes a target high-frequency morphology index and a target root mean square voltage; the second resting reference feature also includes the target high-frequency morphology index; the target high-frequency morphology index is the maximum value of the high-frequency morphology indexes corresponding to each resting lead; the target root mean square voltage is the minimum value of the root mean square voltages corresponding to each resting lead.

在其中一个实施例中,若所述目标心电检测还包括负荷运动心电检测,则所述心电数据包括所述受测者的年龄、静息心电信号与运动心电信号,所述参考特征包括第一静息参考特征与第一运动参考特征;所述按照所述目标心电检测对所述心电数据中QRS波群的高频成分进行分析得到相应参考特征,包括:In one embodiment, if the target ECG detection also includes load exercise ECG detection, the ECG data includes the age, resting ECG signal and exercise ECG signal of the subject, and the reference feature includes a first resting reference feature and a first exercise reference feature; the high-frequency components of the QRS complex in the ECG data are analyzed according to the target ECG detection to obtain the corresponding reference features, including:

分析所述静息心电信号中QRS波群的高频成分得到高频QRS包络曲线;Analyzing the high-frequency components of the QRS complex in the resting electrocardiogram signal to obtain a high-frequency QRS envelope curve;

根据所述高频QRS包络曲线与所述年龄确定第一静息参考特征;所述第一静息参考特征包括静息阳性导联数量、静息临界导联数量、第一目标导联数量与第二目标导联数量;所述第一目标导联数量是指相应高频形态指数大于或等于第一指数阈值的静息导联的数量;所述第二目标导联数量是指相应均方根电压小于或等于第一电压阈值的静息导联的数量;Determine a first resting reference feature according to the high-frequency QRS envelope curve and the age; the first resting reference feature includes the number of resting positive leads, the number of resting critical leads, the number of first target leads and the number of second target leads; the first target lead number refers to the number of resting leads whose corresponding high-frequency morphology index is greater than or equal to the first index threshold; the second target lead number refers to the number of resting leads whose corresponding root mean square voltage is less than or equal to the first voltage threshold;

分析所述运动心电信号中QRS波群的高频成分得到高频QRS波形曲线;Analyzing the high-frequency components of the QRS complex in the exercise electrocardiogram signal to obtain a high-frequency QRS waveform curve;

根据所述运动心电信号确定所述受测者的最大心率;Determining the maximum heart rate of the subject according to the exercise electrocardiogram signal;

根据所述高频QRS波形曲线、所述年龄与所述最大心率确定第一运动参考特征;所述第一运动参考特征包括运动阳性导联数量、运动临界导联数量、第三目标导联数量、第四目标导联数量与第五目标导联数量;所述第三目标导联数量是指相应第一振幅下降相对值大于或等于第一相对值阈值的运动导联的数量;所述第四目标导联数量是指相应高频QRS波形曲线在第一时间段内呈下降与上升反复波动趋势的运动导联的数量;所述第五目标导联数量是指相应第二振幅下降相对值大于或等于第二相对值阈值的运动导联的数量。A first motion reference feature is determined according to the high-frequency QRS waveform curve, the age and the maximum heart rate; the first motion reference feature includes the number of motion-positive leads, the number of motion-critical leads, the number of third target leads, the number of fourth target leads and the number of fifth target leads; the third target lead number refers to the number of motion leads whose corresponding first amplitude decrease relative value is greater than or equal to the first relative value threshold; the fourth target lead number refers to the number of motion leads whose corresponding high-frequency QRS waveform curve shows a trend of repeated decrease and increase within a first time period; the fifth target lead number refers to the number of motion leads whose corresponding second amplitude decrease relative value is greater than or equal to the second relative value threshold.

在其中一个实施例中,所述参考特征还包括第二静息参考特征与第二运动参考特征;所述按照所述目标心电检测对所述心电数据中QRS波群的高频成分进行分析得到相应参考特征,还包括:In one embodiment, the reference feature further includes a second resting reference feature and a second motion reference feature; the step of analyzing the high frequency components of the QRS complex in the electrocardiogram data according to the target electrocardiogram detection to obtain the corresponding reference feature further includes:

根据所述高频QRS包络曲线与所述年龄确定第二静息参考特征;所述第二静息参考特征包括所述静息阳性导联数量、所述静息临界导联数量与所述第一目标导联数量;Determining a second resting reference feature according to the high-frequency QRS envelope curve and the age; the second resting reference feature includes the number of resting positive leads, the number of resting critical leads and the first target lead number;

根据所述高频QRS波形曲线、所述年龄与所述最大心率确定第二运动参考特征;所述第二运动参考特征包括所述运动阳性导联数量与所述运动临界导联数量;Determining a second motion reference feature according to the high-frequency QRS waveform curve, the age and the maximum heart rate; the second motion reference feature includes the number of motion-positive leads and the number of motion-critical leads;

所述根据所述参考特征确定心脏风险评估等级与心脏风险类型,包括:The determining of the cardiac risk assessment level and the cardiac risk type according to the reference feature comprises:

根据所述第一静息参考特征确定第一风险评估等级;determining a first risk assessment level according to the first resting reference feature;

根据所述第二静息参考特征与所述第二运动参考特征确定第二风险评估等级;determining a second risk assessment level according to the second rest reference feature and the second motion reference feature;

根据所述第一运动参考特征确定第三风险评估等级;determining a third risk assessment level according to the first motion reference feature;

根据所述第一风险评估等级、所述第二风险评估等级与所述第三风险评估等级确定心脏风险评估等级与心脏风险类型。A cardiac risk assessment level and a cardiac risk type are determined according to the first risk assessment level, the second risk assessment level, and the third risk assessment level.

在其中一个实施例中,所述第一静息参考特征还包括目标高频形态指数与目标均方根电压;所述第二静息参考特征还包括所述目标高频形态指数;所述目标高频形态指数为各静息导联对应的高频形态指数中的最大值;所述目标均方根电压为各静息导联对应的均方根电压中的最小值;第一运动参考特征还包括各运动导联对应的第一振幅下降相对值与第二振幅下降相对值;所述第二运动参考特征还包括各运动导联对应的第二振幅下降相对值。In one embodiment, the first resting reference feature also includes a target high-frequency morphology index and a target root mean square voltage; the second resting reference feature also includes the target high-frequency morphology index; the target high-frequency morphology index is the maximum value of the high-frequency morphology indexes corresponding to each resting lead; the target root mean square voltage is the minimum value of the root mean square voltages corresponding to each resting lead; the first motion reference feature also includes a first relative amplitude decrease value and a second relative amplitude decrease value corresponding to each motion lead; the second motion reference feature also includes a second relative amplitude decrease value corresponding to each motion lead.

在其中一个实施例中,所述方法还包括:In one embodiment, the method further comprises:

根据所述心电数据按照所述心脏风险类型确定相应风险评估特征;Determining corresponding risk assessment features according to the cardiac risk type based on the electrocardiogram data;

根据所述风险评估特征确定相应心脏风险类型的关注级别。A concern level of the corresponding cardiac risk type is determined according to the risk assessment characteristics.

一种心脏风险评估装置,所述装置包括:A cardiac risk assessment device, comprising:

获取模块,用于获取与临床适应症相匹配的目标心电检测所对应的心电数据;所述临床适应症用于指示能否进行负荷运动心电检测;所述目标心电检测至少包括静息心电检测;An acquisition module, used to acquire ECG data corresponding to a target ECG test that matches a clinical indication; the clinical indication is used to indicate whether a load exercise ECG test can be performed; the target ECG test at least includes a resting ECG test;

特征确定模块,用于按照所述目标心电检测对所述心电数据中QRS波群的高频成分进行分析得到相应参考特征;A feature determination module, used for analyzing the high-frequency components of the QRS complex in the ECG data according to the target ECG detection to obtain corresponding reference features;

风险评估模块,用于根据所述参考特征确定心脏风险评估等级与心脏风险类型;所述心脏风险评估等级作为对受测者进行分流的参考指标;所述心脏风险类型作为评估所述受测者的心脏可能存在的风险类型的参考指标。The risk assessment module is used to determine the cardiac risk assessment level and the cardiac risk type according to the reference characteristics; the cardiac risk assessment level is used as a reference indicator for triaging the subject; the cardiac risk type is used as a reference indicator for assessing the possible risk type of the subject's heart.

一种计算机设备,包括存储器和处理器,所述存储器存储有计算机程序,所述处理器执行所述计算机程序时实现各方法实施例中的步骤。A computer device includes a memory and a processor, wherein the memory stores a computer program, and the processor implements the steps in each method embodiment when executing the computer program.

一种计算机可读存储介质,其上存储有计算机程序,所述计算机程序被处理器执行时实现各方法实施例中的步骤。A computer-readable storage medium stores a computer program, which implements the steps in various method embodiments when executed by a processor.

上述心脏风险评估方法、装置、计算机设备和存储介质,通过获取与临床适应症相匹配的目标心电检测所对应的心电数据,以及按照目标心电检测对相应心电数据中QRS波群的高频成分进行分析得到相应参考特征,并对参考特征进行评估分析,高效而准确地得到表征受测者心脏出现问题的风险大小的心脏风险评估等级,以及表征心脏可能存在的风险类型的心脏风险类型,由此,能够通过无创方式高效、准确地评估受测者心脏出现问题的风险大小以及风险类型,以供医生参考,以便于医生结合临床症状高效而准确地识别受测者的心脏健康状况,并给出进一步地诊疗和/或检测参考建议,以实现对受测者的导诊、分流。此外,用于评估受测者心脏风险的心电数据,是在与受测者的临床适应症相匹配的目标心电检测过程中采集到的,以便于在保证受测者安全检测的情况下,尽可能全面的获取能够准确评估受测者心脏风险的心电数据,以进一步提高心脏风险评估的准确性,从而进一步提高心脏健康状况识别准确性。The above-mentioned cardiac risk assessment method, device, computer equipment and storage medium obtain the ECG data corresponding to the target ECG detection matching the clinical indication, and analyze the high-frequency components of the QRS wave group in the corresponding ECG data according to the target ECG detection to obtain the corresponding reference features, and evaluate and analyze the reference features, so as to efficiently and accurately obtain the cardiac risk assessment level that characterizes the risk of the subject's heart problems, and the cardiac risk type that characterizes the possible risk type of the heart. Thus, the risk size and risk type of the subject's heart problems can be efficiently and accurately assessed in a non-invasive manner for the doctor's reference, so that the doctor can efficiently and accurately identify the subject's heart health status in combination with clinical symptoms, and give further diagnosis and/or detection reference suggestions to achieve the guidance and diversion of the subject. In addition, the ECG data used to assess the subject's heart risk is collected during the target ECG detection process matching the subject's clinical indication, so as to obtain ECG data that can accurately assess the subject's heart risk as comprehensively as possible while ensuring the subject's safe detection, so as to further improve the accuracy of cardiac risk assessment, thereby further improving the accuracy of cardiac health status identification.

附图说明BRIEF DESCRIPTION OF THE DRAWINGS

图1为一个实施例中心脏风险评估方法的流程示意图;FIG1 is a schematic diagram of a process flow of a cardiac risk assessment method in one embodiment;

图2为一个实施例中高频QRS波形曲线的示意图;FIG2 is a schematic diagram of a high-frequency QRS waveform curve in one embodiment;

图3为一个实施例中高频QRS包络曲线的示意图;FIG3 is a schematic diagram of a high frequency QRS envelope curve in one embodiment;

图4为另一个实施例中心脏风险评估方法的流程示意图;FIG4 is a schematic flow chart of a cardiac risk assessment method in another embodiment;

图5为一个实施例中心脏风险评估装置的结构框图;FIG5 is a block diagram of a cardiac risk assessment device in one embodiment;

图6为一个实施例中计算机设备的内部结构图。FIG. 6 is a diagram showing the internal structure of a computer device in one embodiment.

具体实施方式DETAILED DESCRIPTION

为了使本申请的目的、技术方案及优点更加清楚明白,以下结合附图及实施例,对本申请进行进一步详细说明。应当理解,此处描述的具体实施例仅仅用以解释本申请,并不用于限定本申请。In order to make the purpose, technical solution and advantages of the present application more clearly understood, the present application is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

本申请提供的心脏风险评估方法,可以应用于终端,也可以应用于服务器,还可以应用于包括终端与服务器的交互系统,并通过终端和服务器的交互实现,在此不作具体限定。终端可以但不限于是各种个人计算机、笔记本电脑、智能手机、平板电脑、心电监测设备和便携式可穿戴设备,服务器可以用独立的服务器或者是多个服务器组成的服务器集群来实现。The cardiac risk assessment method provided in the present application can be applied to a terminal, a server, or an interactive system including a terminal and a server, and is implemented through the interaction between the terminal and the server, which is not specifically limited here. The terminal can be, but is not limited to, various personal computers, laptops, smart phones, tablet computers, electrocardiogram monitoring devices, and portable wearable devices, and the server can be implemented as an independent server or a server cluster consisting of multiple servers.

在一个实施例中,如图1所示,提供了一种心脏风险评估方法,以该方法应用于服务器为例进行说明,具体包括以下步骤:In one embodiment, as shown in FIG1 , a cardiac risk assessment method is provided, which is described by taking the method applied to a server as an example, and specifically includes the following steps:

S102,获取与临床适应症相匹配的目标心电检测所对应的心电数据;临床适应症用于指示能否进行负荷运动心电检测;目标心电检测至少包括静息心电检测。S102, obtaining ECG data corresponding to a target ECG test that matches a clinical indication; the clinical indication is used to indicate whether a load exercise ECG test can be performed; the target ECG test at least includes a resting ECG test.

其中,临床适应症用于指示相应受测者所适用的心电检测,具体用于指示相应受测者能否进行负荷运动心电检测,具体包括是否低血糖、低血压与心梗急性发作期,以及生命体征是否稳定等临床数据。若生命体征稳定、且排除低血糖、低血压与心梗急性发作期,表明相应受测者能够进行负荷运动心电检测,则该临床适应症相匹配的目标心电检测包括静息心电检测与负荷运动心电检测,否则,表明相应受测者不能够进行负荷运动心电检测,则临床适应症相匹配的目标心电检测包括静息心电检测。受测者在静息心电检测过程中处于静息状态。受测者在负荷运动心电检测过程中处于运动状态,以通过运动增加受测者的心脏负荷。目标心电检测是指受测者所适用的心电检测的类型。可以理解,上述临床适应症的具体内容仅作为示例,并不用于具体限定。Among them, the clinical indication is used to indicate the ECG test applicable to the corresponding subject, specifically to indicate whether the corresponding subject can perform a load exercise ECG test, specifically including clinical data such as whether hypoglycemia, hypotension and acute attack of myocardial infarction are present, and whether vital signs are stable. If the vital signs are stable and hypoglycemia, hypotension and acute attack of myocardial infarction are excluded, it indicates that the corresponding subject can perform a load exercise ECG test, then the target ECG test matched by the clinical indication includes a resting ECG test and a load exercise ECG test, otherwise, it indicates that the corresponding subject cannot perform a load exercise ECG test, then the target ECG test matched by the clinical indication includes a resting ECG test. The subject is in a resting state during the resting ECG test. The subject is in a state of exercise during the load exercise ECG test to increase the subject's cardiac load through exercise. The target ECG test refers to the type of ECG test applicable to the subject. It can be understood that the specific content of the above clinical indications is only used as an example and is not used for specific limitation.

具体地,获取受测者的心电数据,该心电数据是在目标心电检测过程中采集到的心电数据,该目标心电检测与该受测者的临床适应症相匹配,也即是指该目标心电检测由该受测者的临床适应症确定。Specifically, the ECG data of the subject is obtained, which is the ECG data collected during the target ECG detection process. The target ECG detection matches the clinical indication of the subject, that is, the target ECG detection is determined by the clinical indication of the subject.

在一个实施例中,若目标心电检测包括静息心电检测,则所获取到的心电数据包括受测者的年龄,以及在静息心电检测过程中采集到的静息心电信号。若目标心电检测包括静息心电检测与负荷运动心电检测,则所获取到的心电数据包括受测者的年龄、在静息心电检测过程中采集到的静息心电信号,以及在负荷运动心电检测过程中采集到的运动心电信号。In one embodiment, if the target ECG detection includes a resting ECG detection, the acquired ECG data includes the age of the subject and the resting ECG signal collected during the resting ECG detection. If the target ECG detection includes a resting ECG detection and a load exercise ECG detection, the acquired ECG data includes the age of the subject, the resting ECG signal collected during the resting ECG detection, and the exercise ECG signal collected during the load exercise ECG detection.

S104,按照目标心电检测对心电数据中QRS波群的高频成分进行分析得到相应参考特征。S104, analyzing the high frequency components of the QRS complex in the ECG data according to the target ECG detection to obtain corresponding reference features.

具体地,心电数据中包括多个反映左、右心室除极电位和时间的变化的QRS波群,每个QRS波群包括高频成分与低频成分。每个目标心电检测对应有相应的参考特征,通过分别对每个目标心电检测对应的心电数据中QRS波群的高频成分进行分析,能够确定该目标心电检测所对应的参考特征。Specifically, the ECG data includes multiple QRS complexes that reflect the changes in the left and right ventricular depolarization potentials and time, and each QRS complex includes high-frequency components and low-frequency components. Each target ECG detection corresponds to a corresponding reference feature, and by analyzing the high-frequency components of the QRS complex in the ECG data corresponding to each target ECG detection, the reference feature corresponding to the target ECG detection can be determined.

在一个实施例中,若目标心电检测包括静息心电检测,则对静息心电信号中QRS波群的高频成分进行分析得到相应参考特征。若目标心电检测包括静息心电检测与负荷运动心电检测,则对静息心电信号中QRS波群的高频成分进行分析得到相应参考特征,以及对运动心电信号中QRS波群的高频成分进行分析得到相应参考特征。其中,基于静息心电信号确定的参考特征可理解为静息参考特征,静息参考特征至少包括第一静息参考特征,还可包括第二静息参考特征,基于运动心电信号确定的参考特征可理解为运动参考特征,运动参考特征至少包括第一运动参考特征,还可包括第二运动参考特征。In one embodiment, if the target ECG detection includes a resting ECG detection, the high-frequency components of the QRS complex in the resting ECG signal are analyzed to obtain corresponding reference features. If the target ECG detection includes a resting ECG detection and a load exercise ECG detection, the high-frequency components of the QRS complex in the resting ECG signal are analyzed to obtain corresponding reference features, and the high-frequency components of the QRS complex in the exercise ECG signal are analyzed to obtain corresponding reference features. Among them, the reference features determined based on the resting ECG signal can be understood as resting reference features, and the resting reference features at least include a first resting reference feature and may also include a second resting reference feature. The reference features determined based on the exercise ECG signal can be understood as motion reference features, and the motion reference features at least include a first motion reference feature and may also include a second motion reference feature.

S106,根据参考特征确定心脏风险评估等级与心脏风险类型;心脏风险评估等级作为对受测者进行分流的参考指标;心脏风险类型作为评估受测者的心脏可能存在的风险类型的参考指标。S106, determining a cardiac risk assessment level and a cardiac risk type based on the reference characteristics; the cardiac risk assessment level is used as a reference indicator for triaging the subject; the cardiac risk type is used as a reference indicator for assessing the possible risk type of the subject's heart.

其中,心脏风险评估等级用于表征心脏出现问题的风险大小,如心脏风险评估等级越高,表征心脏出现问题的风险越大,以便于医生结合受测者的临床症状对该受测者进行导诊、分流。心脏风险类型用于表征受测者心脏可能存在的风险类型,也即是用于表征受测者可能存在的心脏问题的类型,具体包括心肌损伤风险、心脏性猝死风险、冠脉狭窄风险与其他中的至少一种,心肌损伤风险表征存在心肌损伤的可能性,心脏性猝死风险表征存在心脏性猝死的可能性,冠脉狭窄风险表征存在冠脉狭窄的可能性,其他表征不存在心肌损伤、心脏性猝死与冠脉狭窄中的任意一种风险的可能性。可以理解,医生还可结合心脏风险评估等级、心脏风险类型与临床症状对受测者进行分流。Among them, the cardiac risk assessment level is used to characterize the risk of heart problems. For example, the higher the cardiac risk assessment level, the greater the risk of heart problems, so that doctors can guide and divert the subject in combination with the subject's clinical symptoms. The cardiac risk type is used to characterize the type of risk that the subject's heart may have, that is, it is used to characterize the type of heart problems that the subject may have, specifically including the risk of myocardial damage, the risk of sudden cardiac death, the risk of coronary artery stenosis, and at least one of the others. The risk of myocardial damage characterizes the possibility of myocardial damage, the risk of sudden cardiac death characterizes the possibility of sudden cardiac death, the risk of coronary artery stenosis characterizes the possibility of coronary artery stenosis, and the others characterize the possibility of no risk of any of myocardial damage, sudden cardiac death, and coronary artery stenosis. It can be understood that doctors can also divert subjects in combination with the cardiac risk assessment level, cardiac risk type, and clinical symptoms.

具体地,对所得到的参考特征进行评估分析得到相应心脏风险评估分数,根据心脏风险评估分数确定相应心脏风险评估等级与心脏风险类型,以供医生参考,以便于医生准确了解受测者心脏出现问题的风险大小,以及可能存在的风险类型,从而准确识别受测者的心脏健康状况。若目标心电检测包括静息心电检测,则根据静息参考指标确定心脏风险评估分数,若目标心电检测包括静息心电检测与负荷运动心电检测,则根据静息参考指标与负荷运动参考指标确定心脏风险评估分数,进而确定受测者的心脏风险评估等级与心脏风险类型。Specifically, the obtained reference features are evaluated and analyzed to obtain a corresponding cardiac risk assessment score, and the corresponding cardiac risk assessment level and cardiac risk type are determined based on the cardiac risk assessment score for reference by doctors, so that doctors can accurately understand the risk of the subject's heart problems and the possible risk types, thereby accurately identifying the subject's heart health status. If the target ECG test includes a resting ECG test, the cardiac risk assessment score is determined based on the resting reference index; if the target ECG test includes a resting ECG test and a load exercise ECG test, the cardiac risk assessment score is determined based on the resting reference index and the load exercise reference index, thereby determining the subject's cardiac risk assessment level and cardiac risk type.

在一个实施例中,按照目标心电检测将所得到的参考特征输入相应预设的风险评估函数或预先训练好的风险评估模型,得到相应心脏风险评估分数。可以理解,将参考特征输入预先训练好的风险评估模型,该风险评估模型也可直接输出相应心脏风险评估等级,还可同步输出相应心脏风险类型,具体由用于训练该风险评估模型的训练数据集(包括输入特征与相应输出特征)确定。In one embodiment, the reference features obtained are input into a corresponding preset risk assessment function or a pre-trained risk assessment model according to the target ECG detection to obtain a corresponding cardiac risk assessment score. It can be understood that the reference features are input into a pre-trained risk assessment model, and the risk assessment model can also directly output the corresponding cardiac risk assessment level and synchronously output the corresponding cardiac risk type, which is specifically determined by the training data set (including input features and corresponding output features) used to train the risk assessment model.

在一个实施例中,将心脏风险评估分数与各预设分数区间进行比较,以确定相应心脏风险评估等级,进而确定心脏风险类型。以心脏风险评估等级包括依次升高的第一等级至第六等级共六个等级为例,针对每个心脏风险评估等级预配置有相应的预设分数区间,分别为[0,10]、[11,30]、[31,50]、[51,60]、[61,70]、[71,100],若心脏风险评估分数处于[0,10],则将心脏风险评估等级确定为第一等级,将心脏风险类型确定为其他。In one embodiment, the cardiac risk assessment score is compared with each preset score interval to determine the corresponding cardiac risk assessment level, and then determine the cardiac risk type. Taking the cardiac risk assessment level including six levels from the first level to the sixth level that increase in sequence as an example, a corresponding preset score interval is pre-configured for each cardiac risk assessment level, which are [0, 10], [11, 30], [31, 50], [51, 60], [61, 70], and [71, 100], respectively. If the cardiac risk assessment score is between [0, 10], the cardiac risk assessment level is determined to be the first level, and the cardiac risk type is determined to be others.

在一个实施例中,若输出的心脏风险评估等级与心脏风险类型供导诊医生参考,则对受测者进行分流包括建议受测者去住院部就诊、建议受测者去门诊就诊、建议受测者回家(无需就诊)。可以理解,若建议受测者去门诊或住院部就诊,还可根据心脏风险类型将受测者分流至相应科室或医生。其中,导诊医生比如体检机构或体检科室的医生,还比如医院中针对心血管疾病科室设置的、用于对准备前往心血管疾病科室就诊的受测者进行导诊、分流的医生,在此不做具体限制。举例说明,以心脏风险评估等级包括六个等级为例,若针对受测者输出的心脏风险评估等级为第一等级,导诊医生可建议受测者回家,若心脏风险评估等级为第二等级或第三等级,可建议受测者去门诊就诊,否则,则建议受测者去住院部就诊。值得说明的是,导诊医生还需结合受测者的临床症状对受测者进行导诊、分流。In one embodiment, if the output cardiac risk assessment level and cardiac risk type are provided for reference by the guiding doctor, the subject is triaged including suggesting the subject to go to the inpatient department for treatment, suggesting the subject to go to the outpatient department for treatment, and suggesting the subject to go home (no need for treatment). It can be understood that if the subject is recommended to go to the outpatient department or the inpatient department for treatment, the subject can also be diverted to the corresponding department or doctor according to the cardiac risk type. Among them, the guiding doctor is such as a doctor in a physical examination institution or a physical examination department, and also such as a doctor set up for the cardiovascular disease department in the hospital for guiding and diverting the subject who is about to go to the cardiovascular disease department for treatment, and no specific restrictions are made here. For example, taking the cardiac risk assessment level including six levels as an example, if the cardiac risk assessment level output for the subject is the first level, the guiding doctor can suggest the subject to go home, if the cardiac risk assessment level is the second level or the third level, the subject can be suggested to go to the outpatient department for treatment, otherwise, the subject is suggested to go to the inpatient department for treatment. It is worth mentioning that the guiding doctor also needs to guide and divert the subjects based on their clinical symptoms.

在一个实施例中,若输出的心脏风险评估等级与心脏风险类型供门诊医生参考,则对受测者进行分流包括建议受测者住院、建议受测者定期复查、建议受测者若出现不适症状再就诊。举例说明,以心脏风险评估等级包括六个等级为例,若针对受测者输出的心脏风险评估等级为第一等级,门诊医生可建议受测者若出现不适症状再就诊,若心脏风险评估等级为第二等级或第三等级,可建议受测者定期复查,否则,则建议受测者住院。值得说明的是,门诊医生还需结合受测者的临床症状提供进一步的诊疗和/或检测参考建议。In one embodiment, if the output cardiac risk assessment level and cardiac risk type are for reference by outpatient doctors, the subjects are triaged including recommending hospitalization for the subjects, recommending regular checkups for the subjects, and recommending that the subjects seek medical attention again if they experience any discomfort symptoms. For example, taking the cardiac risk assessment level as an example, if the cardiac risk assessment level output for the subject is the first level, the outpatient doctor may recommend that the subject seek medical attention again if any discomfort symptoms occur. If the cardiac risk assessment level is the second or third level, the subject may be recommended to have regular checkups. Otherwise, the subject is recommended to be hospitalized. It is worth noting that outpatient doctors are also required to provide further diagnosis and treatment and/or testing reference suggestions based on the clinical symptoms of the subject.

上述心脏风险评估方法,通过获取与临床适应症相匹配的目标心电检测所对应的心电数据,以及按照目标心电检测对相应心电数据中QRS波群的高频成分进行分析得到相应参考特征,并对参考特征进行评估分析,高效而准确地得到表征受测者心脏出现问题的风险大小的心脏风险评估等级,以及表征心脏可能存在的风险类型的心脏风险类型,由此,能够通过无创方式高效、准确地评估受测者心脏出现问题的风险大小以及风险类型,以供医生参考,以便于医生结合临床症状高效而准确地识别受测者的心脏健康状况,并给出进一步地诊疗和/或检测参考建议,以实现对受测者的导诊、分流。此外,用于评估受测者心脏风险的心电数据,是在与受测者的临床适应症相匹配的目标心电检测过程中采集到的,以便于在保证受测者安全检测的情况下,尽可能全面的获取能够准确评估受测者心脏风险的心电数据,从而进一步提高心脏风险评估的准确性,从而进一步提高心脏健康状况识别准确性。The above-mentioned cardiac risk assessment method obtains the ECG data corresponding to the target ECG test that matches the clinical indications, and analyzes the high-frequency components of the QRS wave group in the corresponding ECG data according to the target ECG test to obtain the corresponding reference features, and evaluates and analyzes the reference features, so as to efficiently and accurately obtain the cardiac risk assessment level that characterizes the risk of the subject's heart problems, and the cardiac risk type that characterizes the possible risk type of the heart. Thus, the risk size and risk type of the subject's heart problems can be efficiently and accurately assessed in a non-invasive manner for the doctor's reference, so that the doctor can efficiently and accurately identify the subject's heart health status in combination with clinical symptoms, and give further diagnosis and/or testing reference suggestions to achieve guidance and diversion of the subject. In addition, the ECG data used to assess the subject's heart risk is collected during the target ECG test that matches the subject's clinical indications, so as to obtain ECG data that can accurately assess the subject's heart risk as comprehensively as possible while ensuring the subject's safe test, thereby further improving the accuracy of cardiac risk assessment, thereby further improving the accuracy of cardiac health status identification.

在一个实施例中,若目标心电检测仅包括静息心电检测,则心电数据包括受测者的年龄与静息心电信号,参考特征包括第一静息参考特征;S104包括:分析静息心电信号中QRS波群的高频成分得到高频QRS包络曲线;根据高频QRS包络曲线与年龄确定第一静息参考特征;第一静息参考特征包括静息阳性导联数量、静息临界导联数量、第一目标导联数量与第二目标导联数量;第一目标导联数量是指相应高频形态指数大于或等于第一指数阈值的静息导联的数量;第二目标导联数量是指相应均方根电压小于或等于第一电压阈值的静息导联的数量。In one embodiment, if the target ECG detection only includes resting ECG detection, the ECG data includes the age and resting ECG signal of the subject, and the reference feature includes a first resting reference feature; S104 includes: analyzing the high-frequency components of the QRS complex in the resting ECG signal to obtain a high-frequency QRS envelope curve; determining the first resting reference feature based on the high-frequency QRS envelope curve and age; the first resting reference feature includes the number of resting positive leads, the number of resting critical leads, the first target lead number and the second target lead number; the first target lead number refers to the number of resting leads whose corresponding high-frequency morphology index is greater than or equal to the first index threshold; the second target lead number refers to the number of resting leads whose corresponding root mean square voltage is less than or equal to the first voltage threshold.

其中,静息阳性导联数量是指相应导联阳性指标指示为阳性的静息导联的数量,能够用于评估静息状态下的心肌缺血风险,二者成正相关关系。静息临界导联数量是指相应导联阳性指标指示为临界的静息导联的数量,能够用于评估静息状态下心肌缺血的临界风险,结合该参考特征能更准确地识别心肌缺血情况。导联阳性指标指示为阳性,用于表征相应静息导联的高频形态指数大于或等于第二指数阈值、且受测者的年龄大于或等于预设年龄,或者,用于表征相应静息导联的高频形态指数大于或等于第三指数阈值、且受测者的年龄小于预设年龄。导联阳性指标指示为临界,用于表征相应静息导联的高频形态指数大于第二指数阈值且小于第三指数阈值、且受测者的年龄小于预设年龄。第一指数阈值、第二指数阈值与第三指数阈值具体可自定义,比如第一指数阈值为20%,第二指数阈值为8%,第三指数阈值为15%。第一电压阈值具体可根据实际情况自定义,比如4uV(微伏)。预设年龄可自定义,比如50岁。Among them, the number of resting positive leads refers to the number of resting leads in which the corresponding lead positive index indicates positive, which can be used to assess the risk of myocardial ischemia in the resting state, and the two are positively correlated. The number of resting critical leads refers to the number of resting leads in which the corresponding lead positive index indicates critical, which can be used to assess the critical risk of myocardial ischemia in the resting state. Combined with this reference feature, myocardial ischemia can be more accurately identified. The lead positive index indicates positive, which is used to characterize that the high-frequency morphological index of the corresponding resting lead is greater than or equal to the second index threshold, and the age of the subject is greater than or equal to the preset age, or, it is used to characterize that the high-frequency morphological index of the corresponding resting lead is greater than or equal to the third index threshold, and the age of the subject is less than the preset age. The lead positive index indicates critical, which is used to characterize that the high-frequency morphological index of the corresponding resting lead is greater than the second index threshold and less than the third index threshold, and the age of the subject is less than the preset age. The first index threshold, the second index threshold and the third index threshold can be customized, for example, the first index threshold is 20%, the second index threshold is 8%, and the third index threshold is 15%. The first voltage threshold can be customized according to actual conditions, such as 4uV (microvolts). The preset age can be customized, such as 50 years old.

具体地,对静息心电信号中的各QRS波群依次进行对齐、求均值、高频滤波处理得到高频QRS波群数据(QRS波群的高频波段数据),或者,对静息心电信号中的QRS波群依次进行高频滤波、对齐、求均值处理得到高频QRS波群数据,或者,通过分析静息心电信号从中提取出高频心电信号,再对高频心电信号中的QRS波群依次进行对齐与求均值处理得到高频QRS波群数据,在此不作具体限定。基于高频QRS波群数据能够形成高频QRS包络曲线,由此,对静息心电信号进行上述数据处理能够得到高频QRS包络曲线。分析每条静息导联对应的高频QRS包络曲线,得到该高频QRS包络曲线上各振幅减小区域的总面积作为第一总面积,以及该高频QRS包络曲线下方总面积作为第二总面积,将第一总面积与第二总面积的比值作为该静息导联对应的高频形态指数。根据受测者的年龄与各静息导联对应的高频形态指数分别确定相应导联阳性指标,筛选并统计相应导联阳性指标指示为阳性的静息导联得到静息阳性导联数量,筛选并统计相应导联阳性指标指示为临界的静息导联得到静息临界导联数量,以及筛选并统计相应高频形态指数大于或等于第一指数阈值的静息导联得到第一目标导联数量。对各条静息导联对应的高频QRS包络曲线(也即是高频QRS波群数据)求均方根,得到相应静息导联的均方根电压,筛选并统计相应均方根电压小于或等于第一电压阈值的静息导联得到第二目标导联数量。Specifically, each QRS complex in the resting ECG signal is aligned, averaged, and high-frequency filtered in sequence to obtain high-frequency QRS complex data (high-frequency band data of the QRS complex), or the QRS complex in the resting ECG signal is high-frequency filtered, aligned, and averaged in sequence to obtain high-frequency QRS complex data, or the high-frequency ECG signal is extracted from the resting ECG signal by analyzing the resting ECG signal, and then the QRS complex in the high-frequency ECG signal is aligned and averaged in sequence to obtain high-frequency QRS complex data, which is not specifically limited here. A high-frequency QRS envelope curve can be formed based on the high-frequency QRS complex data, and thus, the high-frequency QRS envelope curve can be obtained by performing the above data processing on the resting ECG signal. The high-frequency QRS envelope curve corresponding to each resting lead is analyzed to obtain the total area of each amplitude reduction region on the high-frequency QRS envelope curve as the first total area, and the total area below the high-frequency QRS envelope curve as the second total area, and the ratio of the first total area to the second total area is used as the high-frequency morphological index corresponding to the resting lead. According to the age of the subject and the high-frequency morphological index corresponding to each resting lead, the positive index of the corresponding lead is determined respectively, and the resting leads indicated as positive by the positive index of the corresponding lead are screened and counted to obtain the number of resting positive leads, the resting leads indicated as critical by the positive index of the corresponding lead are screened and counted to obtain the number of resting critical leads, and the resting leads with the corresponding high-frequency morphological index greater than or equal to the first index threshold are screened and counted to obtain the first target lead number. The root mean square of the high-frequency QRS envelope curve (that is, the high-frequency QRS wave group data) corresponding to each resting lead is calculated to obtain the root mean square voltage of the corresponding resting lead, and the resting leads with the corresponding root mean square voltage less than or equal to the first voltage threshold are screened and counted to obtain the second target lead number.

在一个实施例中,若参考特征包括第一静息参考特征,则心脏风险评估分数包括第一风险评估分数。将基于受测者的年龄与静息心电信号确定的第一静息参考特征,输入针对静息心电检测预配置的第一风险评估函数或预先训练好的第一风险评估模型中,得到相应第一风险评估分数,将第一风险评估分数与各预设分数区间进行比较,得到第一风险评估等级,根据第一风险评估等级确定第一风险类型,并将第一风险评估等级确定为心脏风险评估等级,以及将第一风险类型确定为心脏风险类型。举例说明,若第一风险评估等级为第一等级,则第一风险类型为其他,否则,第一风险类型为心肌炎风险。In one embodiment, if the reference feature includes a first resting reference feature, the cardiac risk assessment score includes a first risk assessment score. The first resting reference feature determined based on the subject's age and resting ECG signal is input into a first risk assessment function preconfigured for resting ECG detection or a pre-trained first risk assessment model to obtain a corresponding first risk assessment score, the first risk assessment score is compared with each preset score interval to obtain a first risk assessment level, the first risk type is determined according to the first risk assessment level, the first risk assessment level is determined as a cardiac risk assessment level, and the first risk type is determined as a cardiac risk type. For example, if the first risk assessment level is the first level, the first risk type is others, otherwise, the first risk type is myocarditis risk.

在一个实施例中,针对静息心电检测预配置的第一风险评估函数的表达式如下:In one embodiment, the expression of the first risk assessment function preconfigured for resting ECG detection is as follows:

其中,为第一风险评估分数,为静息临界导联数量,为静息阳性导联数量,为第一目标导联数量,为第二目标导联数量。in, is the first risk assessment score, is the number of resting critical leads, is the number of resting positive leads, is the first target lead number, is the second target lead number.

在一个实施例中,第一静息参考特征还包括目标高频形态指数与目标均方根电压,其中,目标高频形态指数为各静息导联对应的高频形态指数中的最大值,目标均方根电压为各静息导联对应的均方根电压的最小值。在本实施例中,针对静息心电检测预配置的第一风险评估函数的表达式,还可表示如下:In one embodiment, the first resting reference feature also includes a target high frequency morphology index and a target root mean square voltage, wherein the target high frequency morphology index is the maximum value of the high frequency morphology indexes corresponding to each resting lead, and the target root mean square voltage is the minimum value of the root mean square voltage corresponding to each resting lead. In this embodiment, the expression of the first risk assessment function preconfigured for resting ECG detection can also be expressed as follows:

其中,为基于目标高频形态指数确定的附加分数,为基于目标均方根电压确定的附加分数,分别基于以下表达式得到:in, is an additional score determined based on the target high frequency morphology index, is the additional fraction determined based on the target RMS voltage, and is obtained based on the following expressions:

其中,为目标高频形态指数,为目标均方根电压,单位为uV(微伏)。in, is the target high-frequency morphological index, is the target RMS voltage in uV (microvolt).

上述实施例中,若临床适应症指示受测者不能进行负荷运动心电检测,则根据在静息心电检测过程中采集到的静息心电信号与受测者的年龄确定第一静息参考特征,以便于根据第一静息参考特征准确评估心脏风险评估等级与心脏风险类型。In the above embodiment, if the clinical indication indicates that the subject cannot undergo stress exercise ECG testing, the first resting reference feature is determined based on the resting ECG signal collected during the resting ECG testing process and the age of the subject, so as to accurately assess the cardiac risk assessment level and cardiac risk type based on the first resting reference feature.

在一个实施例中,参考特征还包括第二静息参考特征;S104还包括:根据高频QRS包络曲线与年龄确定第二静息参考特征;第二静息参考特征包括静息阳性导联数量、静息临界导联数量与第一目标导联数量;S106包括:根据第一静息参考特征确定第一风险评估等级;根据第二静息参考特征确定第二风险评估等级;根据第一风险评估等级与第二风险评估等级确定心脏风险评估等级与心脏风险类型。In one embodiment, the reference feature also includes a second resting reference feature; S104 also includes: determining the second resting reference feature based on the high-frequency QRS envelope curve and age; the second resting reference feature includes the number of resting positive leads, the number of resting critical leads and the number of first target leads; S106 includes: determining a first risk assessment level based on the first resting reference feature; determining a second risk assessment level based on the second resting reference feature; determining a cardiac risk assessment level and a cardiac risk type based on the first risk assessment level and the second risk assessment level.

其中,第二静息参考特征为第一静息参考特征的子集,由此,在确定第一静息参考特征时,也可同步确定第二静息参考特征。第一静息参考特征用于评估出现心肌炎的可能性,第二静息参考特征用于评估出现心脏性猝死的可能性。The second resting reference feature is a subset of the first resting reference feature, so when the first resting reference feature is determined, the second resting reference feature can also be determined synchronously. The first resting reference feature is used to assess the possibility of myocarditis, and the second resting reference feature is used to assess the possibility of sudden cardiac death.

在一个实施例中,若参考特征包括第一静息参考特征与第二静息参考特征,则心脏风险评估分数包括第一风险评估分数与第二风险评估分数。将第一静息参考特征输入针对静息心电检测预配置的第一风险评估函数或预先训练好的第一风险评估模型中,得到相应第一风险评估分数,将第一风险评估分数与各预设分数区间进行比较,得到第一风险评估等级。将第二静息参考特征输入针对静息心电检测预配置的第二风险评估函数或第二风险评估模型中,得到相应第二风险评估分数,将第二风险评估分数与各预设分数区间进行比较,得到第二风险评估等级。将第一风险评估等级与第二风险评估等级中的最大值(最高等级)确定为心脏风险评估等级。根据第一风险评估等级确定第一风险类型,以及根据第二风险评估等级确定第二风险类型,并根据第一风险类型与第二风险类型确定心脏风险类型。In one embodiment, if the reference feature includes a first resting reference feature and a second resting reference feature, the cardiac risk assessment score includes a first risk assessment score and a second risk assessment score. The first resting reference feature is input into a first risk assessment function preconfigured for resting ECG detection or a pre-trained first risk assessment model to obtain a corresponding first risk assessment score, and the first risk assessment score is compared with each preset score interval to obtain a first risk assessment level. The second resting reference feature is input into a second risk assessment function preconfigured for resting ECG detection or a second risk assessment model to obtain a corresponding second risk assessment score, and the second risk assessment score is compared with each preset score interval to obtain a second risk assessment level. The maximum value (highest level) of the first risk assessment level and the second risk assessment level is determined as the cardiac risk assessment level. The first risk type is determined according to the first risk assessment level, and the second risk type is determined according to the second risk assessment level, and the cardiac risk type is determined according to the first risk type and the second risk type.

举例说明,若第一风险评估等级为第二等级,第二风险评估等级为第一等级,则将心脏风险评估等级确定为第二等级,将第一风险类型确定为心肌炎风险,将第二风险类型确定为其他,进而将心脏风险类型确定为心肌炎风险。若第一风险评估等级为第三等级,第二风险评估等级为第二等级,则将心脏风险评估等级确定为第三等级,将第一风险类型确定为心肌炎风险,将第二风险类型确定为心脏性猝死风险,进而将心脏风险类型确定为心肌炎风险与心脏性猝死风险。For example, if the first risk assessment level is the second level and the second risk assessment level is the first level, the cardiac risk assessment level is determined to be the second level, the first risk type is determined to be myocarditis risk, the second risk type is determined to be others, and the cardiac risk type is determined to be myocarditis risk. If the first risk assessment level is the third level and the second risk assessment level is the second level, the cardiac risk assessment level is determined to be the third level, the first risk type is determined to be myocarditis risk, the second risk type is determined to be sudden cardiac death risk, and the cardiac risk type is determined to be myocarditis risk and sudden cardiac death risk.

在一个实施例中,针对静息心电检测预配置的第二风险评估函数的表达式如下:In one embodiment, the expression of the second risk assessment function preconfigured for resting ECG detection is as follows:

其中,为基于第二静息参考特征确定的第二风险评估分数,为静息临界导联数量,为静息阳性导联数量,为第一目标导联数量。in, is a second risk assessment score determined based on a second resting reference feature, is the number of resting critical leads, is the number of resting positive leads, is the first target lead number.

上述实施例中,若临床适应症指示受测者不能进行负荷运动心电检测,则根据静息心电信号与受测者的年龄确定第一静息参考特征与第二静息参考特征,以便于结合第一静息参考特征与第二静息参考特征更准确地评估心脏风险评估等级与心脏风险类型。In the above embodiment, if the clinical indication indicates that the subject cannot undergo stress exercise ECG testing, the first resting reference feature and the second resting reference feature are determined based on the resting ECG signal and the age of the subject, so as to more accurately evaluate the cardiac risk assessment level and cardiac risk type in combination with the first resting reference feature and the second resting reference feature.

在一个实施例中,第一静息参考特征还包括目标高频形态指数与目标均方根电压;第二静息参考特征还包括目标高频形态指数;目标高频形态指数为各静息导联对应的高频形态指数中的最大值;目标均方根电压为各静息导联对应的均方根电压中的最小值。In one embodiment, the first resting reference feature also includes a target high-frequency morphology index and a target root mean square voltage; the second resting reference feature also includes a target high-frequency morphology index; the target high-frequency morphology index is the maximum value of the high-frequency morphology indexes corresponding to each resting lead; the target root mean square voltage is the minimum value of the root mean square voltages corresponding to each resting lead.

在一个实施例中,针对静息心电检测预配置的第二风险评估函数的表达式,还可表示如下:In one embodiment, the expression of the second risk assessment function preconfigured for resting ECG detection can also be expressed as follows:

其中,为基于目标高频形态指数确定的附加分数,基于以下表达式得到:in, is an additional score determined based on the target high-frequency morphology index, based on the following expression:

其中,为目标高频形态指数。in, is the target high-frequency morphology index.

上述实施例中,基于包括附加参考特征的第一静息参考特征与第二静息参考特征,能够更准确地识别、区分心脏可能存在的风险类型,以及更准确地评估心脏出现问题的风险大小,以便于医生结合临床症状更准确地识别受测者的心脏健康状况,从而给出进一步诊疗、检测等参考建议,以实现更准确地导诊、分流。In the above embodiment, based on the first resting reference feature and the second resting reference feature including the additional reference feature, it is possible to more accurately identify and distinguish the possible risk types of the heart, and more accurately assess the risk of heart problems, so that the doctor can more accurately identify the heart health status of the subject in combination with the clinical symptoms, and thus give reference suggestions for further diagnosis, treatment, testing, etc., so as to achieve more accurate guidance and diversion.

在一个实施例中,若目标心电检测还包括负荷运动心电检测,则心电数据包括受测者的年龄、静息心电信号与运动心电信号,参考特征包括第一静息参考特征与第一运动参考特征;S104包括:分析静息心电信号中QRS波群的高频成分得到高频QRS包络曲线;根据高频QRS包络曲线与年龄确定第一静息参考特征;第一静息参考特征包括静息阳性导联数量、静息临界导联数量、第一目标导联数量与第二目标导联数量;第一目标导联数量是指相应高频形态指数大于或等于第一指数阈值的静息导联的数量;第二目标导联数量是指相应均方根电压小于或等于第一电压阈值的静息导联的数量;分析运动心电信号中QRS波群的高频成分得到高频QRS波形曲线;根据运动心电信号确定受测者的最大心率;根据高频QRS波形曲线、年龄与最大心率确定第一运动参考特征;第一运动参考特征包括运动阳性导联数量、运动临界导联数量、第三目标导联数量、第四目标导联数量与第五目标导联数量;第三目标导联数量是指相应第一振幅下降相对值大于或等于第一相对值阈值的运动导联的数量;第四目标导联数量是指相应高频QRS波形曲线在第一时间段内呈下降与上升反复波动趋势的运动导联的数量;第五目标导联数量是指相应第二振幅下降相对值大于或等于第二相对值阈值的运动导联的数量。In one embodiment, if the target ECG detection also includes load exercise ECG detection, the ECG data includes the age, resting ECG signal and exercise ECG signal of the subject, and the reference features include a first resting reference feature and a first exercise reference feature; S104 includes: analyzing the high-frequency components of the QRS complex in the resting ECG signal to obtain a high-frequency QRS envelope curve; determining the first resting reference feature according to the high-frequency QRS envelope curve and the age; the first resting reference feature includes the number of resting positive leads, the number of resting critical leads, the first target lead number and the second target lead number; the first target lead number refers to the number of resting leads whose corresponding high-frequency morphology index is greater than or equal to the first index threshold; the second target lead number refers to the number of resting leads whose corresponding root mean square voltage is less than or equal to the first voltage threshold; analyzing A high-frequency QRS waveform curve is obtained from the high-frequency components of the QRS wave group in the exercise ECG signal; the maximum heart rate of the subject is determined according to the exercise ECG signal; the first exercise reference feature is determined according to the high-frequency QRS waveform curve, age and maximum heart rate; the first exercise reference feature includes the number of exercise-positive leads, the number of exercise-critical leads, the number of third target leads, the number of fourth target leads and the number of fifth target leads; the number of third target leads refers to the number of exercise leads whose corresponding first amplitude decrease relative value is greater than or equal to the first relative value threshold; the number of fourth target leads refers to the number of exercise leads whose corresponding high-frequency QRS waveform curve shows a trend of repeated decrease and increase within a first time period; the number of fifth target leads refers to the number of exercise leads whose corresponding second amplitude decrease relative value is greater than or equal to the second relative value threshold.

其中,运动心电信号是在负荷运动心电检测过程中采集到的心电信号。负荷运动心电检测过程包括多个阶段,具体可依次包括静息阶段、运动阶段和恢复阶段等三个阶段,运动心电信号包括各阶段的心电信号,阶段的划分不限于此,具体可根据实际情况进行划分。最大心率是指受测者在整个负荷运动心电检测过程中的心率的最大值。运动阳性导联数量是指相应导联阳性指标指示为阳性的运动导联的数量,能够用于评估负荷运动状态下的心肌缺血风险,二者成正相关关系。运动临界导联数量是指相应导联阳性指标指示为临界的运动导联的数量,能够用于评估负荷运动状态下心肌缺血的临界风险,结合该参考特征能够更准确地评估负荷运动状态下的心肌缺血情况。Among them, the exercise ECG signal is the ECG signal collected during the load exercise ECG detection process. The load exercise ECG detection process includes multiple stages, which can specifically include three stages, namely, the resting stage, the exercise stage and the recovery stage. The exercise ECG signal includes the ECG signals of each stage. The division of the stages is not limited to this, and can be specifically divided according to actual conditions. The maximum heart rate refers to the maximum heart rate of the subject during the entire load exercise ECG detection process. The number of exercise positive leads refers to the number of exercise leads where the corresponding lead positive index indicates positive, which can be used to assess the risk of myocardial ischemia under load exercise, and the two are positively correlated. The number of critical exercise leads refers to the number of exercise leads where the corresponding lead positive index indicates critical, which can be used to assess the critical risk of myocardial ischemia under load exercise. Combined with this reference feature, the myocardial ischemia under load exercise can be more accurately assessed.

导联阳性指标指示为阳性,用于表征相应运动导联的第一振幅下降相对值大于第三相对值阈值、振幅下降绝对值大于预设绝对值阈值、受测者的年龄小于预设年龄、且受测者的最大心率大于目标心率的80%,或者,用于表征相应运动导联的第一振幅下降相对值大于第四相对值阈值、振幅下降绝对值大于预设绝对值阈值、受测者的年龄小于预设年龄、且受测者的最大心率小于或等于目标心率的80%,或者,用于表征相应运动导联的第一振幅下降相对值大于第四相对值阈值、振幅下降绝对值大于预设绝对值阈值、受测者的年龄大于或等于预设年龄、且受测者的最大心率大于目标心率的80%,或者,用于表征相应运动导联的第一振幅下降相对值大于第五相对值阈值、振幅下降绝对值大于预设绝对值阈值、受测者的年龄大于或等于预设年龄、且受测者的最大心率小于或等于目标心率的80%。第一相对值阈值、第二相对值阈值、第三相对值阈值、第四相对值阈值、第五相对值阈值、预设绝对值阈值、预设年龄根据实际情况自定义,比如分别为55%、40%、60%、50%、40%、1uV(微伏)、50岁。目标心率根据受测者的年龄确定,如目标心率=(220-受测者年龄)×85%。The lead positive indicator indicates a positive value, which is used to characterize that the first amplitude decrease relative value of the corresponding motion lead is greater than the third relative value threshold, the absolute value of the amplitude decrease is greater than the preset absolute value threshold, the age of the subject is less than the preset age, and the maximum heart rate of the subject is greater than 80% of the target heart rate, or, it is used to characterize that the first amplitude decrease relative value of the corresponding motion lead is greater than the fourth relative value threshold, the absolute value of the amplitude decrease is greater than the preset absolute value threshold, the age of the subject is less than the preset age, and the maximum heart rate of the subject is less than or equal to 80% of the target heart rate, or, it is used to characterize that the first amplitude decrease relative value of the corresponding motion lead is greater than the fourth relative value threshold, the absolute value of the amplitude decrease is greater than the preset absolute value threshold, the age of the subject is greater than or equal to the preset age, and the maximum heart rate of the subject is greater than 80% of the target heart rate, or, it is used to characterize that the first amplitude decrease relative value of the corresponding motion lead is greater than the fifth relative value threshold, the absolute value of the amplitude decrease is greater than the preset absolute value threshold, the age of the subject is greater than or equal to the preset age, and the maximum heart rate of the subject is less than or equal to 80% of the target heart rate. The first relative value threshold, the second relative value threshold, the third relative value threshold, the fourth relative value threshold, the fifth relative value threshold, the preset absolute value threshold, and the preset age are customized according to the actual situation, such as 55%, 40%, 60%, 50%, 40%, 1uV (microvolt), and 50 years old. The target heart rate is determined according to the age of the subject, such as target heart rate = (220-subject age) × 85%.

导联阳性指标指示为临界,用于表征相应运动导联的第一振幅下降相对值大于第三相对值阈值的90%且小于或等于第三相对值阈值、振幅下降绝对值大于预设绝对值阈值、受测者的年龄小于预设年龄、且受测者的最大心率大于目标心率的80%,或者,用于表征相应运动导联的第一振幅下降相对值大于第四相对值阈值的90%且小于或等于第四相对值阈值、振幅下降绝对值大于预设绝对值阈值、受测者的年龄小于预设年龄、且受测者的最大心率小于或等于目标心率的80%,或者,用于表征相应运动导联的第一振幅下降相对值大于第四相对值阈值的90%且小于或等于第四相对值阈值、振幅下降绝对值大于预设绝对值阈值、受测者的年龄大于或等于预设年龄、且受测者的最大心率大于目标心率的80%,或者,用于表征相应运动导联的第一振幅下降相对值大于第五相对值阈值的90%且小于或等于第五相对值阈值、振幅下降绝对值大于预设绝对值阈值、受测者的年龄大于或等于预设年龄、且受测者的最大心率小于或等于目标心率的80%。The lead positive indicator is critical, which is used to characterize that the first amplitude decrease relative value of the corresponding motion lead is greater than 90% of the third relative value threshold and less than or equal to the third relative value threshold, the absolute value of the amplitude decrease is greater than the preset absolute value threshold, the age of the subject is less than the preset age, and the maximum heart rate of the subject is greater than 80% of the target heart rate, or the first amplitude decrease relative value of the corresponding motion lead is greater than 90% of the fourth relative value threshold and less than or equal to the fourth relative value threshold, the absolute value of the amplitude decrease is greater than the preset absolute value threshold, the age of the subject is less than the preset age, and the maximum heart rate of the subject is less than or equal to 80% of the target heart rate. %, or, the first amplitude decrease relative value used to characterize the corresponding motion lead is greater than 90% of the fourth relative value threshold and less than or equal to the fourth relative value threshold, the absolute value of the amplitude decrease is greater than the preset absolute value threshold, the age of the subject is greater than or equal to the preset age, and the maximum heart rate of the subject is greater than 80% of the target heart rate, or, the first amplitude decrease relative value used to characterize the corresponding motion lead is greater than 90% of the fifth relative value threshold and less than or equal to the fifth relative value threshold, the absolute value of the amplitude decrease is greater than the preset absolute value threshold, the age of the subject is greater than or equal to the preset age, and the maximum heart rate of the subject is less than or equal to 80% of the target heart rate.

第一时间段包括运动前一段时间、运动中和运动后一段时间,运动前一段时间位于静息阶段,运动中包括整个运动阶段,运动后一段时间位于恢复阶段,运动前一段时间、运动中和运动后一段时间是连续的时间段。第二时间段包括运动前一段时间与运动中的一段时间,或者,第二时间段包括运动中的一段时间,运动前一段时间与运动中的一段时间为连续的时间段,运动中的一段时间可根据实际情况自定义,比如运动中的前3分钟。第一时间段具体可包括第二时间段,也即是指第二时间段为第一时间段的子区间。第二振幅下降相对值用于表征高频QRS波形曲线在第二时间段内的下降坡度或陡降程度,若第二振幅下降相对值超过第二相对值阈值,表明该下降坡度或陡降程度足够大,则表征存在冠脉狭窄的可能性。第一振幅下降相对值可理解为高频QRS波形曲线在第一时间段内的振幅下降相对值,第二振幅下降相对值可理解为高频QRS波形曲线在第二时间段内的振幅下降相对值。The first time period includes a period of time before exercise, during exercise and after exercise, the period of time before exercise is in the resting stage, the period of time during exercise includes the entire exercise stage, and the period of time after exercise is in the recovery stage. The period of time before exercise, during exercise and after exercise are continuous time periods. The second time period includes a period of time before exercise and a period of time during exercise, or the second time period includes a period of time during exercise, the period of time before exercise and the period of time during exercise are continuous time periods, and the period of time during exercise can be customized according to actual conditions, such as the first 3 minutes of exercise. The first time period may specifically include the second time period, that is, the second time period is a sub-interval of the first time period. The second amplitude decrease relative value is used to characterize the descending slope or steepness of the high-frequency QRS waveform curve in the second time period. If the second amplitude decrease relative value exceeds the second relative value threshold, it indicates that the descending slope or steepness is large enough, which indicates the possibility of coronary stenosis. The first amplitude decrease relative value can be understood as the relative value of the amplitude decrease of the high-frequency QRS waveform curve in the first time period, and the second amplitude decrease relative value can be understood as the relative value of the amplitude decrease of the high-frequency QRS waveform curve in the second time period.

具体地,按照本申请的一个或多个实施例中公开的第一静息参考特征确定方式,根据静息心电信号与受测者的年龄确定相应第一静息参考特征,在此不再赘述。运动心电信号包括受测者在整个负荷运动心电检测过程中各次心跳对应的QRS波群。通过窗口函数按照时序与预设移动步长将运动心电信号划分为多个心电信号子集,每个心电信号子集包括多次心跳对应的QRS波群。对于每个心电信号子集,对其所包括的多次心跳对应的QRS波群,依次进行对齐、求均值与高频滤波处理得到相应高频QRS波群数据(QRS波群的高频波段数据),对该高频QRS波群数据求均方根得到相应均方根电压,作为该心电信号子集对应的均方根电压/强度/振幅。按照时序对各心电信号子集对应的均方根电压/强度/振幅进行曲线平滑处理,得到运动心电信号对应的高频QRS波形曲线,由此,高频QRS波形曲线又可理解为高频QRS时间-强度曲线。其中,窗口函数的窗口长度与预设移动步长均可根据实际需求自定义,比如,窗口长度设置为10秒,预设移动步长设置为10秒或一次心跳周期,一次心跳周期是指相邻两次心跳之间的时间间隔,在此不作具体限定。按照时序是指按照信号的采集时间/负荷运动心电检测过程推进的检测时间的先后顺序。按照现有技术公开的从心电信号中提取心率序列的方式,从运动心电数据中提取受测者的心率序列,并从心率序列中筛选最大值作为受测者的最大心率。Specifically, according to the first resting reference feature determination method disclosed in one or more embodiments of the present application, the corresponding first resting reference feature is determined according to the resting ECG signal and the age of the subject, which will not be repeated here. The exercise ECG signal includes the QRS wave group corresponding to each heartbeat of the subject during the entire load exercise ECG detection process. The exercise ECG signal is divided into multiple ECG signal subsets according to the timing and the preset moving step size through a window function, and each ECG signal subset includes QRS wave groups corresponding to multiple heartbeats. For each ECG signal subset, the QRS wave groups corresponding to the multiple heartbeats included therein are aligned, averaged and high-frequency filtered in turn to obtain the corresponding high-frequency QRS wave group data (high-frequency band data of the QRS wave group), and the high-frequency QRS wave group data is root-mean-squared to obtain the corresponding root-mean-square voltage, which is used as the root-mean-square voltage/intensity/amplitude corresponding to the ECG signal subset. The root mean square voltage/intensity/amplitude corresponding to each subset of ECG signals is smoothed according to the timing to obtain the high-frequency QRS waveform curve corresponding to the exercise ECG signal. Therefore, the high-frequency QRS waveform curve can be understood as a high-frequency QRS time-intensity curve. Among them, the window length and the preset moving step of the window function can be customized according to actual needs. For example, the window length is set to 10 seconds, and the preset moving step is set to 10 seconds or one heartbeat cycle. One heartbeat cycle refers to the time interval between two adjacent heartbeats, which is not specifically limited here. According to the timing, it refers to the order of detection time promoted by the signal acquisition time/load exercise ECG detection process. According to the method of extracting heart rate sequence from ECG signal disclosed in the prior art, the heart rate sequence of the subject is extracted from the exercise ECG data, and the maximum value from the heart rate sequence is selected as the maximum heart rate of the subject.

进一步地,从第一时间段内的高频QRS波形曲线上选取均方根电压最大的点作为第一参考点,从第一时间段内的高频QRS波形曲线上选取时间晚于第一参考点、且均方根电压最小的点作为第二参考点,将第一参考点的均方根电压与第二参考点的均方根电压作差得到第一振幅下降绝对值,将第一振幅下降绝对值与第一参考点的均方根电压的比值确定为第一振幅下降相对值。筛选并统计相应第一振幅下降相对值大于或等于第一相对值阈值的运动导联得到第三目标导联数量。根据第一振幅下降相对值、第一振幅下降绝对值、受测者的年龄与最大心率确定相应高频QRS波形曲线的导联阳性指标,作为相应运动导联所对应的导联阳性指标。筛选并统计相应导联阳性指标指示为阳性的运动导联得到运动阳性导联数量,以及筛选并统计相应导联阳性指标指示为临界的运动导联得到运动临界导联数量。分析各运动导联对应的高频QRS波形曲线在第一时间段内的变化趋势,以筛选并统计相应高频QRS波形曲线在第一时间段内呈下降与上升反复波动趋势的运动导联,得到第四目标导联数量。Further, a point with the largest root mean square voltage is selected from the high-frequency QRS waveform curve within the first time period as the first reference point, and a point with a time later than the first reference point and the smallest root mean square voltage is selected from the high-frequency QRS waveform curve within the first time period as the second reference point, and the root mean square voltage of the first reference point is subtracted from the root mean square voltage of the second reference point to obtain the first amplitude decrease absolute value, and the ratio of the first amplitude decrease absolute value to the root mean square voltage of the first reference point is determined as the first amplitude decrease relative value. The motion leads whose corresponding first amplitude decrease relative value is greater than or equal to the first relative value threshold are screened and counted to obtain the third target lead number. The lead positive index of the corresponding high-frequency QRS waveform curve is determined according to the first amplitude decrease relative value, the first amplitude decrease absolute value, the age of the subject and the maximum heart rate, as the lead positive index corresponding to the corresponding motion lead. The motion leads whose corresponding lead positive index indicates positive are screened and counted to obtain the number of motion positive leads, and the motion leads whose corresponding lead positive index indicates critical are screened and counted to obtain the number of motion critical leads. The change trend of the high-frequency QRS waveform curve corresponding to each motion lead in the first time period is analyzed to screen and count the motion leads whose corresponding high-frequency QRS waveform curve shows a downward and upward repeated fluctuation trend in the first time period to obtain the fourth target lead number.

从第二时间段内的高频QRS波形曲线上选取均方根电压最小的点作为第三参考点,从第二时间段内高频QRS波形曲线上选取时间早于第三参考点、且均方根电压最大的点作为第四参考点,将第四参考点的均方根电压与第三参考点的均方根电压作差得到第二时间段内的第二振幅下降绝对值,将第二振幅下降绝对值与第四参考点的均方根电压的比值作为第二振幅下降相对值。筛选并统计相应第二振幅下降相对值大于或等于第二相对值阈值的运动导联得到第五目标导联数量。A point with the smallest root mean square voltage is selected from the high-frequency QRS waveform curve in the second time period as the third reference point, and a point with a time earlier than the third reference point and the largest root mean square voltage is selected from the high-frequency QRS waveform curve in the second time period as the fourth reference point. The root mean square voltage of the fourth reference point is subtracted from the root mean square voltage of the third reference point to obtain the second amplitude decrease absolute value in the second time period, and the ratio of the second amplitude decrease absolute value to the root mean square voltage of the fourth reference point is used as the second amplitude decrease relative value. The motion leads whose corresponding second amplitude decrease relative value is greater than or equal to the second relative value threshold are screened and counted to obtain the fifth target lead number.

在一个实施例中,高频QRS波形曲线在第一时间段内呈下降与上升反复波动趋势,是指高频QRS曲线在第一时间段内呈下降趋势的总次数大于或等于两次,且上升趋势与下降趋势交替出现。比如高频QRS波形曲线在第一时间段内呈“W”型或“倒N”型波形。In one embodiment, the high-frequency QRS waveform curve presents a downward and upward repeated fluctuation trend in the first time period, which means that the total number of times the high-frequency QRS curve presents a downward trend in the first time period is greater than or equal to two times, and the upward trend and the downward trend appear alternately. For example, the high-frequency QRS waveform curve presents a "W" type or "inverted N" type waveform in the first time period.

在一个实施例中,若参考特征包括第一静息参考特征与第一运动参考特征,则心脏风险评估分数包括第一风险评估分数与第三风险评估分数。按照本申请的一个或多个实施例,根据第一静息参考特征确定相应第一风险评估等级与第一风险类型。将第一运动参考特征输入针对负荷运动心电检测预配置的风险评估函数或预先训练好的风险评估模型,得到相应第三风险评估分数,将第三风险评估分数与各预设分数区间进行比较,得到第三风险评估等级,根据第三风险评估等级确定第三风险类型。将第一风险评估等级与第三风险评估等级中的最高等级确定为心脏风险评估等级,并根据第一风险类型与第三风险类型确定心脏风险类型。举例说明,若第一风险评估等级为第一等级,第三风险评估等级为第五等级,则第一风险类型为其他,第三风险类型为冠脉狭窄风险,则将心脏风险评估等级确定为第五等级,并将心脏风险类型确定为冠脉狭窄风险。In one embodiment, if the reference feature includes a first resting reference feature and a first motion reference feature, the cardiac risk assessment score includes a first risk assessment score and a third risk assessment score. According to one or more embodiments of the present application, the corresponding first risk assessment level and the first risk type are determined according to the first resting reference feature. The first motion reference feature is input into a risk assessment function preconfigured for load exercise ECG detection or a pre-trained risk assessment model to obtain a corresponding third risk assessment score, and the third risk assessment score is compared with each preset score interval to obtain a third risk assessment level, and the third risk type is determined according to the third risk assessment level. The highest level of the first risk assessment level and the third risk assessment level is determined as the cardiac risk assessment level, and the cardiac risk type is determined according to the first risk type and the third risk type. For example, if the first risk assessment level is the first level and the third risk assessment level is the fifth level, the first risk type is others, and the third risk type is coronary stenosis risk, then the cardiac risk assessment level is determined to be the fifth level, and the cardiac risk type is determined to be coronary stenosis risk.

在一个实施例中,针对负荷运动心电检测预配置的风险评估函数的表达式如下:In one embodiment, the expression of the risk assessment function preconfigured for stress exercise ECG detection is as follows:

其中,为第三风险评估分数,为运动临界导联数量,为运动阳性导联数量,为第三目标导联数量,为第四目标导联数量,为第五目标导联数量。in, is the third risk assessment score, is the number of motion critical leads, is the number of motor-positive leads, is the third target lead number, is the fourth target lead number, is the fifth target lead number.

在一个实施例中,第一运动参考特征还包括各运动导联对应的第一振幅下降相对值与第二振幅下降相对值。在本实施例中,针对负荷运动心电检测预配置的风险评估函数的表达式,还可表示如下:In one embodiment, the first motion reference feature also includes a first amplitude drop relative value and a second amplitude drop relative value corresponding to each motion lead. In this embodiment, the expression of the risk assessment function preconfigured for stress exercise ECG detection can also be expressed as follows:

其中,为基于各运动导联对应的第一振幅下降相对值确定的附加分数,为基于各运动导联对应的第二振幅下降相对值确定的附加分数,分别基于以下表达式得到:in, is an additional score determined based on the relative value of the first amplitude decrease corresponding to each motion lead, is an additional score determined based on the relative value of the second amplitude decrease corresponding to each motion lead, and is obtained based on the following expressions:

上述实施例中,若临床适应症指示受测者能进行负荷运动心电检测,则根据在静息心电检测过程中采集到的静息心电信号与受测者的年龄确定第一静息参考特征,以及根据在负荷运动心电检测过程中采集到的运动心电信号与受测者年龄确定第一运动参考特征,以便于根据第一静息参考特征与第一运动参考特征准确评估心脏风险评估等级与心脏风险类型。In the above embodiment, if the clinical indication indicates that the subject can undergo stress exercise ECG testing, a first resting reference feature is determined based on the resting ECG signal collected during the resting ECG testing and the age of the subject, and a first motion reference feature is determined based on the motion ECG signal collected during the stress exercise ECG testing and the age of the subject, so as to accurately assess the cardiac risk assessment level and the cardiac risk type based on the first resting reference feature and the first motion reference feature.

在一个实施例中,参考特征还包括第二静息参考特征与第二运动参考特征;S104还包括:根据高频QRS包络曲线与年龄确定第二静息参考特征;第二静息参考特征包括静息阳性导联数量、静息临界导联数量与第一目标导联数量;根据高频QRS波形曲线、年龄与最大心率确定第二运动参考特征;第二运动参考特征包括运动阳性导联数量与运动临界导联数量;S106包括:根据第一静息参考特征确定第一风险评估等级;根据第二静息参考特征与第二运动参考特征确定第二风险评估等级;根据第一运动参考特征确定第三风险评估等级;根据第一风险评估等级、第二风险评估等级与第三风险评估等级确定心脏风险评估等级与心脏风险类型。In one embodiment, the reference feature also includes a second resting reference feature and a second motion reference feature; S104 also includes: determining the second resting reference feature according to the high-frequency QRS envelope curve and age; the second resting reference feature includes the number of resting positive leads, the number of resting critical leads and the number of first target leads; determining the second motion reference feature according to the high-frequency QRS waveform curve, age and maximum heart rate; the second motion reference feature includes the number of motion positive leads and the number of motion critical leads; S106 includes: determining the first risk assessment level according to the first resting reference feature; determining the second risk assessment level according to the second resting reference feature and the second motion reference feature; determining the third risk assessment level according to the first motion reference feature; determining the cardiac risk assessment level and the cardiac risk type according to the first risk assessment level, the second risk assessment level and the third risk assessment level.

其中,第二静息参考特征为第一静息参考特征的子集,由此,在确定第一静息参考特征时,也可同步确定第二静息参考特征。类似地,第二运动参考特征为第一运动参考特征的子集,由此,在确定第一运动参考特征时,也可同步确定第二运动参考特征。第一静息参考特征用于评估出现心肌炎的可能性,第二静息参考特征与第二运动参考特征用于联合评估出现心脏性猝死的可能性,第一运动参考特征用于评估出现冠脉狭窄的可能性。Among them, the second resting reference feature is a subset of the first resting reference feature, so when the first resting reference feature is determined, the second resting reference feature can also be synchronously determined. Similarly, the second motion reference feature is a subset of the first motion reference feature, so when the first motion reference feature is determined, the second motion reference feature can also be synchronously determined. The first resting reference feature is used to assess the possibility of myocarditis, the second resting reference feature and the second motion reference feature are used to jointly assess the possibility of sudden cardiac death, and the first motion reference feature is used to assess the possibility of coronary artery stenosis.

在一个实施例中,若参考特征包括第一静息参考特征、第二静息参考特征、第一运动参考特征与第二运动参考特征,则心脏风险评估分数包括第一风险评估分数、第二风险评估分数与第三风险评估分数。按照本申请的一个或多个实施例,根据第一静息参考特征确定第一风险评估分数,进而确定第一风险评估等级与第一风险类型,以及根据第一运动参考特征确定第三风险评估分数,进而确定第三风险评估等级与第三风险类型。将第二静息参考特征与第二运动参考特征,输入针对静息心电检测与负荷运动心电检测联合配置的风险评估函数或风险评估模型,得到第二风险评估分数,将第二风险评估分数与各预设分数区间进行比较得到第二风险评估等级,并根据第二风险评估等级确定第二风险类型。进一步地,将第一风险评估等级、第二风险评估等级与第三风险评估等级中的最高等级确定为心脏风险评估等级,并根据第一风险类型、第二风险类型与第三风险类型确定心脏风险类型。In one embodiment, if the reference feature includes a first resting reference feature, a second resting reference feature, a first motion reference feature, and a second motion reference feature, the cardiac risk assessment score includes a first risk assessment score, a second risk assessment score, and a third risk assessment score. According to one or more embodiments of the present application, the first risk assessment score is determined according to the first resting reference feature, and then the first risk assessment level and the first risk type are determined, and the third risk assessment score is determined according to the first motion reference feature, and then the third risk assessment level and the third risk type are determined. The second resting reference feature and the second motion reference feature are input into a risk assessment function or a risk assessment model configured for resting ECG detection and load exercise ECG detection to obtain a second risk assessment score, and the second risk assessment score is compared with each preset score interval to obtain a second risk assessment level, and the second risk type is determined according to the second risk assessment level. Further, the highest level among the first risk assessment level, the second risk assessment level, and the third risk assessment level is determined as the cardiac risk assessment level, and the cardiac risk type is determined according to the first risk type, the second risk type, and the third risk type.

举例说明,若第一风险评估等级为第二等级,第二风险评估等级为第四等级,第三风险评估等级为第三等级,则第一风险类型为心肌炎风险,第二风险类型为心脏性猝死风险,第三风险类型为冠脉狭窄风险,则将心脏风险评估等级确定为第四等级,将心脏风险类型确定为心肌炎风险、心脏性猝死风险与冠脉狭窄风险。For example, if the first risk assessment level is the second level, the second risk assessment level is the fourth level, and the third risk assessment level is the third level, the first risk type is myocarditis risk, the second risk type is sudden cardiac death risk, and the third risk type is coronary artery stenosis risk, then the cardiac risk assessment level is determined to be the fourth level, and the cardiac risk types are determined to be myocarditis risk, sudden cardiac death risk, and coronary artery stenosis risk.

在一个实施例中,针对静息心电检测与负荷运动心电检测联合配置的风险评估函数的表达式,如下:In one embodiment, the expression of the risk assessment function for the joint configuration of resting ECG detection and stress exercise ECG detection is as follows:

其中,为基于第二静息参考特征与第二运动参考特征联合确定的第二风险评估分数,为静息临界导联数量,为静息阳性导联数量,为第一目标导联数量,为运动临界导联数量,为运动阳性导联数量。in, is a second risk assessment score determined jointly based on the second rest reference feature and the second motion reference feature, is the number of resting critical leads, is the number of resting positive leads, is the first target lead number, is the number of motion critical leads, is the number of motion-positive leads.

上述实施例中,若临床适应症指示受测者能进行负荷运动心电检测,则根据静息心电信号与受测者的年龄确定第一静息参考特征与第二静息参考特征,以及根据运动心电信号与受测者的年龄确定第一运动参考特征与第二运动参考特征,以便于结合第一静息参考特征、第二静息参考特征、第一运动参考特征与第二运动参考特征更准确地评估心脏风险评估等级与心脏风险类型。In the above embodiment, if the clinical indication indicates that the subject is capable of undergoing stress exercise ECG testing, the first resting reference feature and the second resting reference feature are determined based on the resting ECG signal and the subject's age, and the first motion reference feature and the second motion reference feature are determined based on the exercise ECG signal and the subject's age, so as to more accurately assess the cardiac risk assessment level and the cardiac risk type by combining the first resting reference feature, the second resting reference feature, the first motion reference feature and the second motion reference feature.

在一个实施例中,第一静息参考特征还包括目标高频形态指数与目标均方根电压;第二静息参考特征还包括目标高频形态指数;目标高频形态指数为各静息导联对应的高频形态指数中的最大值;目标均方根电压为各静息导联对应的均方根电压中的最小值;第一运动参考特征还包括各运动导联对应的第一振幅下降相对值与第二振幅下降相对值;第二运动参考特征还包括各运动导联对应的第二振幅下降相对值。In one embodiment, the first resting reference feature also includes a target high-frequency morphology index and a target root mean square voltage; the second resting reference feature also includes a target high-frequency morphology index; the target high-frequency morphology index is the maximum value of the high-frequency morphology indexes corresponding to each resting lead; the target root mean square voltage is the minimum value of the root mean square voltages corresponding to each resting lead; the first motion reference feature also includes a first amplitude decrease relative value and a second amplitude decrease relative value corresponding to each motion lead; the second motion reference feature also includes a second amplitude decrease relative value corresponding to each motion lead.

在一个实施例中,针对静息心电检测与负荷运动心电检测联合配置的风险评估函数的表达式,还可表示如下:In one embodiment, the expression of the risk assessment function for the joint configuration of resting ECG detection and stress exercise ECG detection can also be expressed as follows:

其中,为基于目标高频形态指数确定的附加分数,为基于各运动导联对应的第二振幅下降相对值确定的附加分数,分别基于以下表达式得到:in, is an additional score determined based on the target high frequency morphology index, is an additional score determined based on the relative value of the second amplitude decrease corresponding to each motion lead, and is obtained based on the following expressions:

其中,为目标高频形态指数。in, is the target high-frequency morphology index.

上述实施例中,基于包括附加参考特征的第一静息参考特征、第二静息参考特征、第一运动参考特征与第二运动参考特征,能够更准确地识别、区分心脏可能存在的风险类型,以及更准确地评估心脏出现问题的风险大小,以便于医生结合临床症状更准确地识别受测者的心脏健康状况,从而给出进一步诊疗、检测等参考建议,以实现更准确地导诊、分流。In the above embodiment, based on the first resting reference feature, the second resting reference feature, the first motion reference feature and the second motion reference feature including the additional reference feature, it is possible to more accurately identify and distinguish the possible risk types of the heart, and more accurately assess the risk of heart problems, so that doctors can more accurately identify the heart health status of the subjects in combination with clinical symptoms, and thus provide reference suggestions for further diagnosis, treatment, testing, etc., to achieve more accurate guidance and diversion.

在一个实施例中,上述心脏风险评估方法还包括:根据心电数据按照心脏风险类型确定相应风险评估特征;根据风险评估特征确定相应心脏风险类型的关注级别。In one embodiment, the cardiac risk assessment method further includes: determining corresponding risk assessment features according to the cardiac risk type based on the electrocardiogram data; and determining a concern level of the corresponding cardiac risk type based on the risk assessment features.

具体地,关注级别表征关注程度的不同,可用于指示受测者出现相应心脏风险类型的可能性大小的不同。在根据心电数据确定心脏风险类型后,根据心电数据按照所确定的每个心脏风险类型确定相应风险评估特征,根据每个心脏风险类型对应的风险评估特征确定相应关注级别,以供医生在诊断过程中参考,以便于医生根据心脏风险类型、关注级别与临床症状能够准确识别受测者的心脏健康状况,从而给出相应的诊疗参考建议。可以理解,还可输出心脏风险评估等级、心脏风险类型对应的风险评估特征中的至少一种,以便于医生还综合考虑该些参考指标识别心脏健康状况。在本实施例中,所输出的心脏风险类型、关注级别等供门诊医生或住院部医生参考,以便于医生结合临床症状准确识别受测者的心脏健康状况,从而给出相应的诊疗或检测参考建议。Specifically, the attention level represents the different degree of attention, which can be used to indicate the different possibilities of the subject to have the corresponding cardiac risk type. After the cardiac risk type is determined according to the ECG data, the corresponding risk assessment feature is determined according to the ECG data according to each determined cardiac risk type, and the corresponding attention level is determined according to the risk assessment feature corresponding to each cardiac risk type, for the doctor's reference in the diagnosis process, so that the doctor can accurately identify the subject's cardiac health status according to the cardiac risk type, the attention level and the clinical symptoms, and thus give corresponding reference suggestions for diagnosis and treatment. It can be understood that at least one of the cardiac risk assessment level and the risk assessment feature corresponding to the cardiac risk type can also be output, so that the doctor can also comprehensively consider these reference indicators to identify the cardiac health status. In this embodiment, the output cardiac risk type, attention level, etc. are provided for reference by outpatient doctors or inpatient doctors, so that the doctor can accurately identify the subject's cardiac health status in combination with clinical symptoms, and thus give corresponding reference suggestions for diagnosis and treatment or testing.

在一个实施例中,将每个心脏风险类型对应的风险评估特征输入针对该心脏风险类型预先训练好的风险评估模型,由该风险评估模型输出相应关注级别,或者,将每个心脏风险类型对应的风险评估特征输入针对该心脏风险类型预配置的风险评估函数或预先训练好的风险评估模型,得到该心脏风险类型对应的风险评估分数,进而确定相应关注级别,或者,将每个心脏风险类型对应的各风险评估特征分别与相应预设参考区间进行比较,以确定各风险评估特征对应的参考等级,并综合各参考等级确定相应关注级别。可以理解,若风险评估特征仅包括用于定量分析的特征,则基于风险评估特征按照上述评估方式确实相应关注级别。若风险评估特征包括用于定性分析的特征与用于定量分析的特征,则可在基于用于定性分析的特征判定存在相应心脏风险类型的情况下,再基于用于定量分析的特征按照上述评估方式确定相应关注级别。对于将关注级别作为输出特征的风险评估模型,也可将用于定性分析的特征与用于定量分析的特征作为输入特征,输入相应风险评估模型,以得到相应关注级别。In one embodiment, the risk assessment feature corresponding to each cardiac risk type is input into a risk assessment model pre-trained for the cardiac risk type, and the risk assessment model outputs the corresponding level of concern, or the risk assessment feature corresponding to each cardiac risk type is input into a risk assessment function pre-configured for the cardiac risk type or a pre-trained risk assessment model to obtain a risk assessment score corresponding to the cardiac risk type, and then determine the corresponding level of concern, or each risk assessment feature corresponding to each cardiac risk type is compared with a corresponding preset reference interval to determine a reference level corresponding to each risk assessment feature, and the corresponding level of concern is determined based on each reference level. It can be understood that if the risk assessment feature only includes features for quantitative analysis, the corresponding level of concern is determined based on the risk assessment feature in the above-mentioned evaluation method. If the risk assessment feature includes features for qualitative analysis and features for quantitative analysis, then when it is determined that the corresponding cardiac risk type exists based on the features for qualitative analysis, the corresponding level of concern can be determined based on the features for quantitative analysis in the above-mentioned evaluation method. For a risk assessment model that uses the level of concern as an output feature, the features for qualitative analysis and the features for quantitative analysis can also be used as input features and input into the corresponding risk assessment model to obtain the corresponding level of concern.

在一个实施例中,心电数据仅包括静息心电信号,若心脏风险类型包括心肌损伤风险,则根据静息心电信号确定心肌损伤风险对应的风险评估特征,若心脏风险类型还包括心脏性猝死风险,则还根据静息心电信号确定心脏性猝死风险对应的风险评估特征。心肌损伤风险对应的风险评估特征包括用于评估心肌炎风险的第一风险评估特征,以及用于评估心衰风险的第二风险评估特征。第一风险评估特征包括静息阳性导联数量,用于确定心肌炎类型,若心肌炎类型为急性心肌炎,则第一风险评估特征还包括目标高频形态指数,若心肌炎类型为慢性心肌炎,则第一风险评估特征还包括目标高频形态指数与肢体导联平均峰值电压,若心肌炎类型为暴发性心肌炎,则第一风险评估特征还包括QRS时限、目标高频形态指数、肢体导联平均峰值电压与各静息导联对应的高频形态指数。其中,目标高频形态指数为各静息导联对应的高频形态指数中的最大值,肢体导联平均峰值电压为各肢体导联的峰值电压的平均值,静息导联包括肢体导联与胸导联。可以理解,第一风险评估特征还可包括第六目标导联数量,用于对心肌炎情况进行定性分析,第六目标导联数量为相应波峰数超过第一数量阈值、且相应导联阳性指标指示为阳性的静息导联的数量,第一数量阈值比如3。第二风险评估特征包括QRS时限、肢体导联平均峰值电压与各静息导联对应的高频形态指数,还可包括静息阳性导联数量,用于对心衰风险进行定量分析,还可包括第六目标导联数量,用于对心衰情况进行定性分析。In one embodiment, the ECG data only includes a resting ECG signal. If the cardiac risk type includes the risk of myocardial injury, the risk assessment feature corresponding to the risk of myocardial injury is determined according to the resting ECG signal. If the cardiac risk type also includes the risk of sudden cardiac death, the risk assessment feature corresponding to the risk of sudden cardiac death is also determined according to the resting ECG signal. The risk assessment feature corresponding to the risk of myocardial injury includes a first risk assessment feature for assessing the risk of myocarditis and a second risk assessment feature for assessing the risk of heart failure. The first risk assessment feature includes the number of resting positive leads, which is used to determine the type of myocarditis. If the type of myocarditis is acute myocarditis, the first risk assessment feature also includes a target high-frequency morphology index. If the type of myocarditis is chronic myocarditis, the first risk assessment feature also includes a target high-frequency morphology index and an average peak voltage of limb leads. If the type of myocarditis is fulminant myocarditis, the first risk assessment feature also includes a QRS duration, a target high-frequency morphology index, an average peak voltage of limb leads, and a high-frequency morphology index corresponding to each resting lead. Among them, the target high-frequency morphology index is the maximum value of the high-frequency morphology index corresponding to each resting lead, the average peak voltage of the limb leads is the average value of the peak voltage of each limb lead, and the resting leads include limb leads and chest leads. It can be understood that the first risk assessment feature may also include the sixth target lead number, which is used to qualitatively analyze the myocarditis situation. The sixth target lead number is the number of resting leads whose corresponding wave peak number exceeds the first quantity threshold and the corresponding lead positive index indicates positive. The first quantity threshold is, for example, 3. The second risk assessment feature includes the QRS duration, the average peak voltage of the limb leads and the high-frequency morphology index corresponding to each resting lead, and may also include the number of resting positive leads, which is used to quantitatively analyze the risk of heart failure, and may also include the sixth target lead number, which is used to qualitatively analyze the heart failure situation.

在本实施例中,心脏性猝死风险对应的风险评估特征包括QRS时限与各静息导联对应的高频形态指数,还包括静息阳性导联数量、心律失常评估指标、目标峰值电压与心动过速评估指标中的至少一项,用于对心脏性猝死风险进行定量分析,还可包括第七目标导联数量,用于对心脏性猝死风险进行定性分析,还可包括QRS碎裂波指标,用于结合第七目标导联数量进行更准确的定性分析。心律失常评估指标包括频发性心律失常与偶发性心律失常。目标峰值电压为各静息导联对应的峰值电压中的最小值。心动过速评估指标用于指示是否存在室性心动过速的可能性。第七导联数量为相应波峰数大于或等于第二数量阈值的静息导联的数量。第二数量阈值比如4。心律失常评估指标与心动过速评估指标,基于由静息心电信号得到的低频心电图确定。QRS碎裂波指标用于指示低频心电图是否存在QRS碎裂波。In this embodiment, the risk assessment features corresponding to the risk of sudden cardiac death include the QRS duration and the high-frequency morphology index corresponding to each resting lead, and also include at least one of the number of resting positive leads, arrhythmia assessment index, target peak voltage and tachycardia assessment index, which are used to quantitatively analyze the risk of sudden cardiac death, and may also include the number of seventh target leads for qualitative analysis of the risk of sudden cardiac death, and may also include QRS fragmentation wave index for more accurate qualitative analysis in combination with the number of seventh target leads. The arrhythmia assessment index includes frequent arrhythmias and occasional arrhythmias. The target peak voltage is the minimum value of the peak voltages corresponding to each resting lead. The tachycardia assessment index is used to indicate whether there is a possibility of ventricular tachycardia. The number of seventh leads is the number of resting leads whose corresponding wave peak number is greater than or equal to the second number threshold. The second number threshold is, for example, 4. The arrhythmia assessment index and the tachycardia assessment index are determined based on the low-frequency electrocardiogram obtained from the resting electrocardiogram signal. The QRS fragmentation index is used to indicate whether there is a QRS fragmentation wave in the low-frequency electrocardiogram.

在一个实施例中,心电数据包括静息心电信号与运动心电信号,若心脏风险类型包括冠脉狭窄风险,则根据运动心电信号确定相应风险评估特征,若心脏风险类型包括心肌损伤风险,则根据静息心电信号确定相应风险评估特征,若心脏风险类型包括心脏性猝死风险,则根据静息心电信号与运动心电信号确定相应风险评估特征。冠脉狭窄风险对应的风险评估特征包括第一振幅下降相对值与第一振幅下降绝对值中的至少一种,用于对冠脉狭窄情况进行定量分析,还可包括运动阳性导联数量,用于对心肌缺血情况进行定量分析,还可包括第二振幅下降相对值,用于对冠脉狭窄情况进行定性分析。心肌损伤风险对应的风险评估特征与上述相应实施例中的一致,在此不再赘述。心脏性猝死风险对应的风险评估特征,包括基于静息心电信号确定的风险评估特征与基于运动心电信号确定的风险评估特征,其中,基于静息心电信号确定的风险评估特征与上述相应实施例中的一致,在此不再赘述,基于运动心电信号确定的风险评估特征包括运动阳性导联数量,还可包括第二振幅下降相对值。In one embodiment, the ECG data includes a resting ECG signal and an exercise ECG signal. If the cardiac risk type includes the risk of coronary artery stenosis, the corresponding risk assessment feature is determined based on the exercise ECG signal. If the cardiac risk type includes the risk of myocardial injury, the corresponding risk assessment feature is determined based on the resting ECG signal. If the cardiac risk type includes the risk of sudden cardiac death, the corresponding risk assessment feature is determined based on the resting ECG signal and the exercise ECG signal. The risk assessment feature corresponding to the risk of coronary artery stenosis includes at least one of a first relative value of amplitude decrease and a first absolute value of amplitude decrease, which is used to quantitatively analyze the coronary artery stenosis. It may also include the number of exercise-positive leads, which is used to quantitatively analyze the myocardial ischemia. It may also include a second relative value of amplitude decrease, which is used to qualitatively analyze the coronary artery stenosis. The risk assessment feature corresponding to the risk of myocardial injury is consistent with that in the above-mentioned corresponding embodiments and will not be repeated here. The risk assessment characteristics corresponding to the risk of sudden cardiac death include risk assessment characteristics determined based on resting ECG signals and risk assessment characteristics determined based on exercise ECG signals. The risk assessment characteristics determined based on resting ECG signals are consistent with those in the above-mentioned corresponding embodiments and will not be repeated here. The risk assessment characteristics determined based on exercise ECG signals include the number of motion-positive leads and may also include the relative value of the second amplitude decrease.

上述实施例中,根据心电数据按照受测者的心脏风险类型确定相应风险评估特征,并基于该风险评估特征进一步确定该心脏风险类型对应的关注级别,以供医生参考,以便于医生结合临床症状更准确地识别受测者的心脏健康状况。In the above embodiment, corresponding risk assessment features are determined according to the subject's cardiac risk type based on the ECG data, and the concern level corresponding to the cardiac risk type is further determined based on the risk assessment features for the doctor's reference, so that the doctor can more accurately identify the subject's cardiac health status in combination with clinical symptoms.

在本申请的一个或多个实施例中,静息心电检测过程中用于采集静息心电信号的静息导联,与负荷运动心电检测过程中用于采集运动心电信号的运动导联,在类型、数量及位置等方面可以相同也可以不同,在此不作具体限定。In one or more embodiments of the present application, the resting leads used to collect resting ECG signals during resting ECG detection and the motion leads used to collect motion ECG signals during load exercise ECG detection may be the same or different in type, quantity, and position, and are not specifically limited here.

在一个实施中,如图2所示,提供了高频QRS波形曲线的示意图。高频QRS波形曲线用于表征在整个负荷运动心电检测过程中,受测者的QRS波群的高频成分的均方根随时间的变化趋势,也即是用于体现整个负荷运动心电检测过程中的能量变化趋势。图2示例了肢体导联aVF对应的高频QRS波形曲线,横坐标是时间,对应负荷运动心电检测过程的检测时间,单位是min(分钟),纵坐标是均方根电压(RMS电压),均方根电压也可以理解为强度或振幅,单位是uV(微伏)。其中,用于确定相应导联阳性指标的第一振幅下降相对值与第一振幅下降绝对值分别为55%与2.9uV。In one implementation, as shown in FIG2 , a schematic diagram of a high-frequency QRS waveform is provided. The high-frequency QRS waveform is used to characterize the change trend of the root mean square of the high-frequency component of the subject's QRS wave group over time during the entire load exercise ECG detection process, that is, to reflect the energy change trend during the entire load exercise ECG detection process. FIG2 illustrates the high-frequency QRS waveform corresponding to the limb lead aVF. The horizontal axis is time, corresponding to the detection time of the load exercise ECG detection process, and the unit is min (minutes). The vertical axis is the root mean square voltage (RMS voltage), which can also be understood as intensity or amplitude, and the unit is uV (microvolt). Among them, the relative value of the first amplitude decrease and the absolute value of the first amplitude decrease used to determine the positive indicator of the corresponding lead are 55% and 2.9uV, respectively.

在一个实施中,如图3所示,提供了高频QRS包络曲线的示意图。高频QRS包络曲线体现的是对静息心电信号中的所有高频QRS波群(QRS波群的高频成分)平均化处理得到的形状图,具体以单个高频QRS波群包络曲线呈现。图3示例了胸导联V5对应的高频QRS包络曲线,横坐标是时间,对应QRS波群的持续时间,单位是ms(毫秒),纵坐标是电压,单位是uV(微伏)。其中,相应导联的高频形态指数为7.1%。In one implementation, as shown in FIG3 , a schematic diagram of a high-frequency QRS envelope curve is provided. The high-frequency QRS envelope curve reflects the shape diagram obtained by averaging all high-frequency QRS complexes (high-frequency components of the QRS complex) in the resting ECG signal, and is specifically presented as a single high-frequency QRS complex envelope curve. FIG3 illustrates the high-frequency QRS envelope curve corresponding to chest lead V5, where the horizontal axis is time, corresponding to the duration of the QRS complex, in ms (milliseconds), and the vertical axis is voltage, in uV (microvolts). Among them, the high-frequency morphology index of the corresponding lead is 7.1%.

如图4所示,在一个实施例中,提供了一种心脏风险评估方法,该方法具体包括以下步骤:As shown in FIG4 , in one embodiment, a cardiac risk assessment method is provided, the method specifically comprising the following steps:

S402,获取与临床适应症相匹配的目标心电检测所对应的心电数据;临床适应症用于指示能否进行负荷运动心电检测;目标心电检测至少包括静息心电检测。S402, obtaining ECG data corresponding to a target ECG test that matches a clinical indication; the clinical indication is used to indicate whether a load exercise ECG test can be performed; the target ECG test at least includes a resting ECG test.

S404,若目标心电检测仅包括静息心电检测,则心电数据包括受测者的年龄与静息心电信号;分析静息心电信号中QRS波群的高频成分得到高频QRS包络曲线。S404, if the target ECG detection only includes resting ECG detection, the ECG data includes the age of the subject and the resting ECG signal; and the high-frequency components of the QRS complex in the resting ECG signal are analyzed to obtain a high-frequency QRS envelope curve.

S406,根据高频QRS包络曲线与年龄确定第一静息参考特征与第二静息参考特征;第一静息参考特征包括静息阳性导联数量、静息临界导联数量、第一目标导联数量、第二目标导联数量、目标高频形态指数与目标均方根电压;第一目标导联数量是指相应高频形态指数大于或等于第一指数阈值的静息导联的数量;第二目标导联数量是指相应均方根电压小于或等于第一电压阈值的静息导联的数量;目标高频形态指数为各静息导联对应的高频形态指数中的最大值;目标均方根电压为各静息导联对应的均方根电压中的最小值;第二静息参考特征包括静息阳性导联数量、静息临界导联数量、第一目标导联数量与目标高频形态指数。S406, determine the first resting reference feature and the second resting reference feature according to the high-frequency QRS envelope curve and age; the first resting reference feature includes the number of resting positive leads, the number of resting critical leads, the first target number of leads, the second target number of leads, the target high-frequency morphology index and the target root mean square voltage; the first target number of leads refers to the number of resting leads whose corresponding high-frequency morphology index is greater than or equal to the first index threshold; the second target number of leads refers to the number of resting leads whose corresponding root mean square voltage is less than or equal to the first voltage threshold; the target high-frequency morphology index is the maximum value of the high-frequency morphology index corresponding to each resting lead; the target root mean square voltage is the minimum value of the root mean square voltage corresponding to each resting lead; the second resting reference feature includes the number of resting positive leads, the number of resting critical leads, the first target number of leads and the target high-frequency morphology index.

S408,根据第一静息参考特征确定第一风险评估等级。S408: Determine a first risk assessment level according to the first rest reference feature.

S410,根据第二静息参考特征确定第二风险评估等级。S410: Determine a second risk assessment level according to a second rest reference feature.

S412,根据第一风险评估等级与第二风险评估等级确定心脏风险评估等级与心脏风险类型;心脏风险评估等级作为对受测者进行分流的参考指标;心脏风险类型作为评估受测者的心脏可能存在的风险类型的参考指标。S412, determining a cardiac risk assessment level and a cardiac risk type according to the first risk assessment level and the second risk assessment level; the cardiac risk assessment level is used as a reference indicator for triaging the subject; the cardiac risk type is used as a reference indicator for assessing the possible risk type of the subject's heart.

S414,若目标心电检测还包括负荷运动心电检测,则心电数据包括受测者的年龄、静息心电信号与运动心电信号;分析静息心电信号中QRS波群的高频成分得到高频QRS包络曲线。S414, if the target ECG test also includes load exercise ECG test, the ECG data includes the age of the subject, resting ECG signal and exercise ECG signal; the high-frequency components of the QRS wave group in the resting ECG signal are analyzed to obtain a high-frequency QRS envelope curve.

S416,根据高频QRS包络曲线与年龄确定第一静息参考特征与第二静息参考特征;第一静息参考特征包括静息阳性导联数量、静息临界导联数量、第一目标导联数量、第二目标导联数量、目标高频形态指数与目标均方根电压;第一目标导联数量是指相应高频形态指数大于或等于第一指数阈值的静息导联的数量;第二目标导联数量是指相应均方根电压小于或等于第一电压阈值的静息导联的数量;目标高频形态指数为各静息导联对应的高频形态指数中的最大值;目标均方根电压为各静息导联对应的均方根电压中的最小值;第二静息参考特征包括静息阳性导联数量、静息临界导联数量、第一目标导联数量与目标高频形态指数。S416, determine the first resting reference feature and the second resting reference feature according to the high-frequency QRS envelope curve and age; the first resting reference feature includes the number of resting positive leads, the number of resting critical leads, the first target number of leads, the second target number of leads, the target high-frequency morphology index and the target root mean square voltage; the first target number of leads refers to the number of resting leads whose corresponding high-frequency morphology index is greater than or equal to the first index threshold; the second target number of leads refers to the number of resting leads whose corresponding root mean square voltage is less than or equal to the first voltage threshold; the target high-frequency morphology index is the maximum value of the high-frequency morphology index corresponding to each resting lead; the target root mean square voltage is the minimum value of the root mean square voltage corresponding to each resting lead; the second resting reference feature includes the number of resting positive leads, the number of resting critical leads, the first target number of leads and the target high-frequency morphology index.

S418,分析运动心电信号中QRS波群的高频成分得到高频QRS波形曲线。S418, analyzing the high-frequency components of the QRS wave group in the exercise electrocardiogram signal to obtain a high-frequency QRS waveform curve.

S420,根据运动心电信号确定受测者的最大心率。S420, determining the maximum heart rate of the subject according to the exercise electrocardiogram signal.

S422,根据高频QRS波形曲线、年龄与最大心率确定第一运动参考特征与第二运动参考特征;第一运动参考特征包括运动阳性导联数量、运动临界导联数量、第三目标导联数量、第四目标导联数量与第五目标导联数量,以及各运动导联对应的第一振幅下降相对值与第二振幅下降相对值;第三目标导联数量是指相应第一振幅下降相对值大于或等于第一相对值阈值的运动导联的数量;第四目标导联数量是指相应高频QRS波形曲线在第一时间段内呈下降与上升反复波动趋势的运动导联的数量;第五目标导联数量是指相应第二振幅下降相对值大于或等于第二相对值阈值的运动导联的数量;第二运动参考特征包括运动阳性导联数量与运动临界导联数量,以及各运动导联对应的第二振幅下降相对值。S422, determining the first motion reference feature and the second motion reference feature according to the high-frequency QRS waveform curve, age and maximum heart rate; the first motion reference feature includes the number of motion-positive leads, the number of motion-critical leads, the number of third target leads, the number of fourth target leads and the number of fifth target leads, as well as the first relative amplitude decrease value and the second relative amplitude decrease value corresponding to each motion lead; the third target lead number refers to the number of motion leads whose corresponding first relative amplitude decrease value is greater than or equal to the first relative value threshold; the fourth target lead number refers to the number of motion leads whose corresponding high-frequency QRS waveform curve shows a trend of repeated fluctuation of decrease and increase within a first time period; the fifth target lead number refers to the number of motion leads whose corresponding second relative amplitude decrease value is greater than or equal to the second relative value threshold; the second motion reference feature includes the number of motion-positive leads and the number of motion-critical leads, as well as the second relative amplitude decrease value corresponding to each motion lead.

S424,根据第一静息参考特征确定第一风险评估等级。S424: Determine a first risk assessment level according to the first rest reference feature.

S426,根据第二静息参考特征与第二运动参考特征确定第二风险评估等级。S426: Determine a second risk assessment level according to the second rest reference feature and the second motion reference feature.

S428,根据第一运动参考特征确定第三风险评估等级。S428: Determine a third risk assessment level according to the first motion reference feature.

S430,根据第一风险评估等级、第二风险评估等级与第三风险评估等级确定心脏风险评估等级与心脏风险类型。S430: Determine a cardiac risk assessment level and a cardiac risk type according to the first risk assessment level, the second risk assessment level, and the third risk assessment level.

S432,根据心电数据按照心脏风险类型确定相应风险评估特征。S432, determining corresponding risk assessment features according to the cardiac risk type based on the ECG data.

S434,根据风险评估特征确定相应心脏风险类型的关注级别。S434, determining the level of concern of the corresponding cardiac risk type according to the risk assessment characteristics.

上述实施例中,若临床适应症指示受测者不能进行负荷运动心电检测,则获取并分析受测者年龄与在静息心电检测过程中采集到的静息心电信号,得到第一静息参考特征与第二静息参考特征,进而确定相应心脏风险评估等级与心脏风险类型。若临床适应症指示受测者能够进行负荷运动心电检测,则获取并分析受测者年龄与在静息心电检测过程中采集到的静息心电信号,得到第一静息参考特征与第二静息参考特征,以及获取并分析年龄与在负荷运动心电检测过程中采集到的运动心电信号,得到第一运动参考特征与第二运动参考特征,并综合考虑各参考特征得到相应心脏风险评估等级与心脏风险类型。通过输出表征受测者心脏出现问题的风险大小的心脏风险评估等级,以及表征心脏可能存在的风险类型的心脏风险类型供医生参考,以便于医生结合临床症状高效而准确地识别受测者的心脏健康状况,并给出进一步地诊疗和/或检测参考建议,以实现对受测者的普筛、导诊与分流。而根据心电数据按照受测者的心脏风险类型确定相应风险评估特征,进而确定心脏风险类型对应的关注级别供医生参考,以便于医生结合临床症状更准确地识别受测者的心脏健康状况,并给出进一步地诊疗参考建议。In the above embodiment, if the clinical indication indicates that the subject cannot undergo stress exercise ECG testing, the subject's age and the resting ECG signal collected during the resting ECG testing process are obtained and analyzed to obtain the first resting reference feature and the second resting reference feature, and then the corresponding cardiac risk assessment level and cardiac risk type are determined. If the clinical indication indicates that the subject can undergo stress exercise ECG testing, the subject's age and the resting ECG signal collected during the resting ECG testing process are obtained and analyzed to obtain the first resting reference feature and the second resting reference feature, and the age and the exercise ECG signal collected during the stress exercise ECG testing process are obtained and analyzed to obtain the first exercise reference feature and the second exercise reference feature, and the corresponding cardiac risk assessment level and cardiac risk type are obtained by comprehensively considering each reference feature. By outputting the cardiac risk assessment level that characterizes the risk of the subject's heart problems and the cardiac risk type that characterizes the possible risk type of the heart for the doctor's reference, the doctor can efficiently and accurately identify the subject's heart health status in combination with clinical symptoms, and give further diagnosis and/or testing reference suggestions to achieve general screening, guidance and triage of the subject. Based on the ECG data, the corresponding risk assessment features are determined according to the subject's heart risk type, and then the corresponding level of concern for the heart risk type is determined for the doctor's reference, so that the doctor can more accurately identify the subject's heart health status in combination with clinical symptoms, and give further diagnosis and treatment reference suggestions.

应该理解的是,虽然图1和图4的流程图中的各个步骤按照箭头的指示依次显示,但是这些步骤并不是必然按照箭头指示的顺序依次执行。除非本文中有明确的说明,这些步骤的执行并没有严格的顺序限制,这些步骤可以以其它的顺序执行。而且,图1和图4中的至少一部分步骤可以包括多个步骤或者多个阶段,这些步骤或者阶段并不必然是在同一时刻执行完成,而是可以在不同的时刻执行,这些步骤或者阶段的执行顺序也不必然是依次进行,而是可以与其它步骤或者其它步骤中的步骤或者阶段的至少一部分轮流或者交替地执行。It should be understood that, although the various steps in the flowcharts of Fig. 1 and Fig. 4 are sequentially displayed according to the indication of the arrows, these steps are not necessarily executed in sequence in the order indicated by the arrows. Unless there is a clear explanation in this article, the execution of these steps is not strictly limited in order, and these steps can be executed in other orders. Moreover, at least a part of the steps in Fig. 1 and Fig. 4 may include multiple steps or multiple stages, and these steps or stages are not necessarily executed at the same time, but can be executed at different times, and the execution order of these steps or stages is not necessarily to be carried out in sequence, but can be executed in turn or alternately with other steps or at least a part of the steps or stages in other steps.

在一个实施例中,如图5所示,提供了一种心脏风险评估装置500,包括:获取模块501、特征确定模块502与风险评估模块503,其中:In one embodiment, as shown in FIG5 , a cardiac risk assessment device 500 is provided, comprising: an acquisition module 501 , a feature determination module 502 and a risk assessment module 503 , wherein:

获取模块501,用于获取与临床适应症相匹配的目标心电检测所对应的心电数据;临床适应症用于指示能否进行负荷运动心电检测;目标心电检测至少包括静息心电检测;The acquisition module 501 is used to acquire ECG data corresponding to a target ECG test that matches a clinical indication; the clinical indication is used to indicate whether a load exercise ECG test can be performed; the target ECG test at least includes a resting ECG test;

特征确定模块502,用于按照目标心电检测对心电数据中QRS波群的高频成分进行分析得到相应参考特征;The feature determination module 502 is used to analyze the high frequency components of the QRS complex in the ECG data according to the target ECG detection to obtain corresponding reference features;

风险评估模块503,用于根据参考特征确定心脏风险评估等级与心脏风险类型;心脏风险评估等级作为对受测者进行分流的参考指标;心脏风险类型作为评估受测者的心脏可能存在的风险类型的参考指标。The risk assessment module 503 is used to determine the cardiac risk assessment level and cardiac risk type according to the reference characteristics; the cardiac risk assessment level is used as a reference indicator for triaging the subject; the cardiac risk type is used as a reference indicator for assessing the possible risk type of the subject's heart.

在一个实施例中,若目标心电检测仅包括静息心电检测,则心电数据包括受测者的年龄与静息心电信号,参考特征包括第一静息参考特征;特征确定模块502,还用于分析静息心电信号中QRS波群的高频成分得到高频QRS包络曲线;根据高频QRS包络曲线与年龄确定第一静息参考特征;第一静息参考特征包括静息阳性导联数量、静息临界导联数量、第一目标导联数量与第二目标导联数量;第一目标导联数量是指相应高频形态指数大于或等于第一指数阈值的静息导联的数量;第二目标导联数量是指相应均方根电压小于或等于第一电压阈值的静息导联的数量。In one embodiment, if the target ECG detection only includes resting ECG detection, the ECG data includes the age and resting ECG signal of the subject, and the reference feature includes a first resting reference feature; the feature determination module 502 is also used to analyze the high-frequency components of the QRS complex in the resting ECG signal to obtain a high-frequency QRS envelope curve; determine the first resting reference feature based on the high-frequency QRS envelope curve and age; the first resting reference feature includes the number of resting positive leads, the number of resting critical leads, the first target lead number and the second target lead number; the first target lead number refers to the number of resting leads whose corresponding high-frequency morphology index is greater than or equal to the first index threshold; the second target lead number refers to the number of resting leads whose corresponding root mean square voltage is less than or equal to the first voltage threshold.

在一个实施例中,参考特征还包括第二静息参考特征;特征确定模块502,还用于根据高频QRS包络曲线与年龄确定第二静息参考特征;第二静息参考特征包括静息阳性导联数量、静息临界导联数量与第一目标导联数量;风险评估模块503,还用于根据第一静息参考特征确定第一风险评估等级;根据第二静息参考特征确定第二风险评估等级;根据第一风险评估等级与第二风险评估等级确定心脏风险评估等级与心脏风险类型。In one embodiment, the reference feature also includes a second resting reference feature; the feature determination module 502 is also used to determine the second resting reference feature based on the high-frequency QRS envelope curve and age; the second resting reference feature includes the number of resting positive leads, the number of resting critical leads and the number of first target leads; the risk assessment module 503 is also used to determine the first risk assessment level based on the first resting reference feature; determine the second risk assessment level based on the second resting reference feature; determine the cardiac risk assessment level and the cardiac risk type based on the first risk assessment level and the second risk assessment level.

在一个实施例中,第一静息参考特征还包括目标高频形态指数与目标均方根电压;第二静息参考特征还包括目标高频形态指数;目标高频形态指数为各静息导联对应的高频形态指数中的最大值;目标均方根电压为各静息导联对应的均方根电压中的最小值。In one embodiment, the first resting reference feature also includes a target high-frequency morphology index and a target root mean square voltage; the second resting reference feature also includes a target high-frequency morphology index; the target high-frequency morphology index is the maximum value of the high-frequency morphology indexes corresponding to each resting lead; the target root mean square voltage is the minimum value of the root mean square voltages corresponding to each resting lead.

在一个实施例中,若目标心电检测还包括负荷运动心电检测,则心电数据包括受测者的年龄、静息心电信号与运动心电信号,参考特征包括第一静息参考特征与第一运动参考特征;特征确定模块502,还用于分析静息心电信号中QRS波群的高频成分得到高频QRS包络曲线;根据高频QRS包络曲线与年龄确定第一静息参考特征;第一静息参考特征包括静息阳性导联数量、静息临界导联数量、第一目标导联数量与第二目标导联数量;第一目标导联数量是指相应高频形态指数大于或等于第一指数阈值的静息导联的数量;第二目标导联数量是指相应均方根电压小于或等于第一电压阈值的静息导联的数量;分析运动心电信号中QRS波群的高频成分得到高频QRS波形曲线;根据运动心电信号确定受测者的最大心率;根据高频QRS波形曲线、年龄与最大心率确定第一运动参考特征;第一运动参考特征包括运动阳性导联数量、运动临界导联数量、第三目标导联数量、第四目标导联数量与第五目标导联数量;第三目标导联数量是指相应第一振幅下降相对值大于或等于第一相对值阈值的运动导联的数量;第四目标导联数量是指相应高频QRS波形曲线在第一时间段内呈下降与上升反复波动趋势的运动导联的数量;第五目标导联数量是指相应第二振幅下降相对值大于或等于第二相对值阈值的运动导联的数量。In one embodiment, if the target ECG detection also includes load exercise ECG detection, the ECG data includes the age, resting ECG signal and exercise ECG signal of the subject, and the reference features include a first resting reference feature and a first exercise reference feature; the feature determination module 502 is also used to analyze the high-frequency components of the QRS wave group in the resting ECG signal to obtain a high-frequency QRS envelope curve; determine the first resting reference feature according to the high-frequency QRS envelope curve and age; the first resting reference feature includes the number of resting positive leads, the number of resting critical leads, the first target lead number and the second target lead number; the first target lead number refers to the number of resting leads whose corresponding high-frequency morphology index is greater than or equal to the first index threshold; the second target lead number refers to the number of resting leads whose corresponding root mean square voltage is less than or equal to the first voltage threshold ; Analyze the high-frequency components of the QRS wave group in the exercise ECG signal to obtain a high-frequency QRS waveform curve; determine the maximum heart rate of the subject based on the exercise ECG signal; determine the first motion reference feature based on the high-frequency QRS waveform curve, age and maximum heart rate; the first motion reference feature includes the number of motion-positive leads, the number of motion-critical leads, the number of third target leads, the number of fourth target leads and the number of fifth target leads; the number of third target leads refers to the number of motion leads whose corresponding first amplitude decrease relative value is greater than or equal to the first relative value threshold; the number of fourth target leads refers to the number of motion leads whose corresponding high-frequency QRS waveform curve shows a trend of repeated decrease and increase within a first time period; the number of fifth target leads refers to the number of motion leads whose corresponding second amplitude decrease relative value is greater than or equal to the second relative value threshold.

在一个实施例中,参考特征还包括第二静息参考特征与第二运动参考特征;特征确定模块502,还用于根据高频QRS包络曲线与年龄确定第二静息参考特征;第二静息参考特征包括静息阳性导联数量、静息临界导联数量与第一目标导联数量;根据高频QRS波形曲线、年龄与最大心率确定第二运动参考特征;第二运动参考特征包括运动阳性导联数量与运动临界导联数量;风险评估模块503,还用于根据第一静息参考特征确定第一风险评估等级;根据第二静息参考特征与第二运动参考特征确定第二风险评估等级;根据第一运动参考特征确定第三风险评估等级;根据第一风险评估等级、第二风险评估等级与第三风险评估等级确定心脏风险评估等级与心脏风险类型。In one embodiment, the reference feature also includes a second resting reference feature and a second motion reference feature; the feature determination module 502 is also used to determine the second resting reference feature based on the high-frequency QRS envelope curve and age; the second resting reference feature includes the number of resting positive leads, the number of resting critical leads and the number of first target leads; the second motion reference feature is determined based on the high-frequency QRS waveform curve, age and maximum heart rate; the second motion reference feature includes the number of motion positive leads and the number of motion critical leads; the risk assessment module 503 is also used to determine the first risk assessment level based on the first resting reference feature; determine the second risk assessment level based on the second resting reference feature and the second motion reference feature; determine the third risk assessment level based on the first motion reference feature; determine the cardiac risk assessment level and the cardiac risk type based on the first risk assessment level, the second risk assessment level and the third risk assessment level.

在一个实施例中,第一静息参考特征还包括目标高频形态指数与目标均方根电压;第二静息参考特征还包括目标高频形态指数;目标高频形态指数为各静息导联对应的高频形态指数中的最大值;目标均方根电压为各静息导联对应的均方根电压中的最小值;第一运动参考特征还包括各运动导联对应的第一振幅下降相对值与第二振幅下降相对值;第二运动参考特征还包括各运动导联对应的第二振幅下降相对值。In one embodiment, the first resting reference feature also includes a target high-frequency morphology index and a target root mean square voltage; the second resting reference feature also includes a target high-frequency morphology index; the target high-frequency morphology index is the maximum value of the high-frequency morphology indexes corresponding to each resting lead; the target root mean square voltage is the minimum value of the root mean square voltages corresponding to each resting lead; the first motion reference feature also includes a first amplitude decrease relative value and a second amplitude decrease relative value corresponding to each motion lead; the second motion reference feature also includes a second amplitude decrease relative value corresponding to each motion lead.

在一个实施例中,特征确定模块502,还用于根据心电数据按照心脏风险类型确定相应风险评估特征;风险评估模块503,还用于根据风险评估特征确定相应心脏风险类型的关注级别。In one embodiment, the feature determination module 502 is further used to determine corresponding risk assessment features according to the cardiac risk type based on the ECG data; the risk assessment module 503 is further used to determine the concern level of the corresponding cardiac risk type based on the risk assessment features.

关于心脏风险评估装置的具体限定可以参见上文中对于心脏风险评估方法的限定,在此不再赘述。上述心脏风险评估装置中的各个模块可全部或部分通过软件、硬件及其组合来实现。上述各模块可以硬件形式内嵌于或独立于计算机设备中的处理器中,也可以以软件形式存储于计算机设备中的存储器中,以便于处理器调用执行以上各个模块对应的操作。For the specific definition of the cardiac risk assessment device, please refer to the definition of the cardiac risk assessment method above, which will not be repeated here. Each module in the above cardiac risk assessment device can be implemented in whole or in part by software, hardware and a combination thereof. Each of the above modules can be embedded in or independent of the processor in the computer device in the form of hardware, or can be stored in the memory of the computer device in the form of software, so that the processor can call and execute the operations corresponding to each of the above modules.

在一个实施例中,提供了一种计算机设备,该计算机设备可以是服务器,其内部结构图可以如图6所示。该计算机设备包括通过系统总线连接的处理器、存储器和网络接口。其中,该计算机设备的处理器用于提供计算和控制能力。该计算机设备的存储器包括非易失性存储介质、内存储器。该非易失性存储介质存储有操作系统、计算机程序和数据库。该内存储器为非易失性存储介质中的操作系统和计算机程序的运行提供环境。该计算机设备的数据库用于存储与临床适应症相匹配的目标心电检测所对应的心电数据。该计算机设备的网络接口用于与外部的终端通过网络连接通信。该计算机程序被处理器执行时以实现一种心脏风险评估方法。In one embodiment, a computer device is provided, which may be a server, and its internal structure diagram may be as shown in FIG6 . The computer device includes a processor, a memory, and a network interface connected via a system bus. The processor of the computer device is used to provide computing and control capabilities. The memory of the computer device includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system, a computer program, and a database. The internal memory provides an environment for the operation of the operating system and the computer program in the non-volatile storage medium. The database of the computer device is used to store ECG data corresponding to target ECG detection that matches clinical indications. The network interface of the computer device is used to communicate with an external terminal via a network connection. When the computer program is executed by the processor, a cardiac risk assessment method is implemented.

本领域技术人员可以理解,图6中示出的结构,仅仅是与本申请方案相关的部分结构的框图,并不构成对本申请方案所应用于其上的计算机设备的限定,具体的计算机设备可以包括比图中所示更多或更少的部件,或者组合某些部件,或者具有不同的部件布置。Those skilled in the art will understand that the structure shown in FIG. 6 is merely a block diagram of a partial structure related to the solution of the present application, and does not constitute a limitation on the computer device to which the solution of the present application is applied. The specific computer device may include more or fewer components than those shown in the figure, or combine certain components, or have a different arrangement of components.

在一个实施例中,还提供了一种计算机设备,包括存储器和处理器,存储器中存储有计算机程序,该处理器执行计算机程序时实现上述各方法实施例中的步骤。In one embodiment, a computer device is further provided, including a memory and a processor, wherein a computer program is stored in the memory, and the processor implements the steps in the above method embodiments when executing the computer program.

在一个实施例中,提供了一种计算机可读存储介质,其上存储有计算机程序,该计算机程序被处理器执行时实现上述各方法实施例中的步骤。In one embodiment, a computer-readable storage medium is provided, on which a computer program is stored. When the computer program is executed by a processor, the steps in the above-mentioned method embodiments are implemented.

本领域普通技术人员可以理解实现上述实施例方法中的全部或部分流程,是可以通过计算机程序来指令相关的硬件来完成,的计算机程序可存储于一非易失性计算机可读取存储介质中,该计算机程序在执行时,可包括如上述各方法的实施例的流程。其中,本申请所提供的各实施例中所使用的对存储器、存储、数据库或其它介质的任何引用,均可包括非易失性和易失性存储器中的至少一种。非易失性存储器可包括只读存储器(Read-OnlyMemory,ROM)、磁带、软盘、闪存或光存储器等。易失性存储器可包括随机存取存储器(Random Access Memory,RAM)或外部高速缓冲存储器。作为说明而非局限,RAM可以是多种形式,比如静态随机存取存储器(Static Random Access Memory,SRAM)或动态随机存取存储器(Dynamic Random Access Memory,DRAM)等。Those of ordinary skill in the art can understand that all or part of the processes in the above-mentioned embodiment methods can be completed by instructing the relevant hardware through a computer program, and the computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above-mentioned methods. Among them, any reference to memory, storage, database or other media used in the embodiments provided in this application may include at least one of non-volatile and volatile memory. Non-volatile memory may include read-only memory (ROM), tape, floppy disk, flash memory or optical memory, etc. Volatile memory may include random access memory (RAM) or external cache memory. As an illustration and not limitation, RAM can be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM).

以上实施例的各技术特征可以进行任意的组合,为使描述简洁,未对上述实施例中的各个技术特征所有可能的组合都进行描述,然而,只要这些技术特征的组合不存在矛盾,都应当认为是本说明书记载的范围。The technical features of the above embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

以上实施例仅表达了本申请的几种实施方式,其描述较为具体和详细,但并不能因此而理解为对发明专利范围的限制。应当指出的是,对于本领域的普通技术人员来说,在不脱离本申请构思的前提下,还可以做出若干变形和改进,这些都属于本申请的保护范围。因此,本申请专利的保护范围应以所附权利要求为准。The above embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the patent of the present application shall be subject to the attached claims.

Claims (10)

1.一种心脏风险评估方法,其特征在于,所述方法包括:1. A cardiac risk assessment method, characterized in that the method includes: 获取与临床适应症相匹配的目标心电检测所对应的心电数据;所述临床适应症用于指示能否进行负荷运动心电检测;所述目标心电检测至少包括静息心电检测;Obtain the ECG data corresponding to the target ECG test that matches the clinical indication; the clinical indication is used to indicate whether stress exercise ECG test can be performed; the target ECG test at least includes resting ECG test; 按照所述目标心电检测对所述心电数据中QRS波群的高频成分进行分析得到相应参考特征;Analyze the high-frequency components of the QRS wave complex in the electrocardiogram data according to the target electrocardiogram detection to obtain corresponding reference features; 根据所述参考特征确定心脏风险评估等级与心脏风险类型;所述心脏风险评估等级作为对受测者进行分流的参考指标;所述心脏风险类型作为评估所述受测者的心脏可能存在的风险类型的参考指标;The cardiac risk assessment level and cardiac risk type are determined according to the reference characteristics; the cardiac risk assessment level is used as a reference index for shunting the subject; the cardiac risk type is used to evaluate the possible risk of the subject's heart Type of reference indicators; 其中,若所述目标心电检测还包括负荷运动心电检测,则所述心电数据包括所述受测者的年龄、静息心电信号与运动心电信号,所述参考特征包括第一静息参考特征与第一运动参考特征;所述按照所述目标心电检测对所述心电数据中QRS波群的高频成分进行分析得到相应参考特征,包括:Wherein, if the target ECG detection also includes stress exercise ECG detection, the ECG data includes the subject's age, resting ECG signal and exercise ECG signal, and the reference feature includes a first Resting reference features and first movement reference features; analyzing the high-frequency components of the QRS wave complex in the ECG data according to the target ECG detection to obtain corresponding reference features, including: 分析所述静息心电信号中QRS波群的高频成分得到高频QRS包络曲线;Analyze the high-frequency components of the QRS wave complex in the resting ECG signal to obtain a high-frequency QRS envelope curve; 根据所述高频QRS包络曲线与所述年龄确定第一静息参考特征;所述第一静息参考特征包括静息阳性导联数量、静息临界导联数量、第一目标导联数量与第二目标导联数量;所述第一目标导联数量是指相应高频形态指数大于或等于第一指数阈值的静息导联的数量;所述第二目标导联数量是指相应均方根电压小于或等于第一电压阈值的静息导联的数量;The first resting reference feature is determined according to the high-frequency QRS envelope curve and the age; the first resting reference feature includes the number of resting positive leads, the number of resting critical leads, and the number of first target leads. and the second target lead number; the first target lead number refers to the number of resting leads whose corresponding high-frequency morphological index is greater than or equal to the first index threshold; the second target lead number refers to the corresponding average The number of resting leads whose root-square voltage is less than or equal to the first voltage threshold; 分析所述运动心电信号中QRS波群的高频成分得到高频QRS波形曲线;Analyze the high-frequency components of the QRS complex in the exercise ECG signal to obtain a high-frequency QRS waveform curve; 根据所述运动心电信号确定所述受测者的最大心率;Determine the maximum heart rate of the subject according to the exercise ECG signal; 根据所述高频QRS波形曲线、所述年龄与所述最大心率确定第一运动参考特征;所述第一运动参考特征包括运动阳性导联数量、运动临界导联数量、第三目标导联数量、第四目标导联数量与第五目标导联数量;所述第三目标导联数量是指相应第一振幅下降相对值大于或等于第一相对值阈值的运动导联的数量;所述第四目标导联数量是指相应高频QRS波形曲线在第一时间段内呈下降与上升反复波动趋势的运动导联的数量;所述第五目标导联数量是指相应第二振幅下降相对值大于或等于第二相对值阈值的运动导联的数量。The first motion reference feature is determined according to the high-frequency QRS waveform curve, the age and the maximum heart rate; the first motion reference feature includes the number of motion positive leads, the number of motion critical leads, and the number of third target leads. , the fourth target lead number and the fifth target lead number; the third target lead number refers to the number of motion leads whose corresponding first amplitude drop relative value is greater than or equal to the first relative value threshold; The number of four target leads refers to the number of motion leads whose corresponding high-frequency QRS waveform curve shows a downward and upward fluctuation trend in the first period of time; the number of fifth target leads refers to the relative value of the corresponding second amplitude decrease. The number of motor leads greater than or equal to the second relative value threshold. 2.根据权利要求1所述的方法,其特征在于,若所述目标心电检测仅包括静息心电检测,则所述心电数据包括所述受测者的年龄与静息心电信号,所述参考特征包括第一静息参考特征;所述按照所述目标心电检测对所述心电数据中QRS波群的高频成分进行分析得到相应参考特征,包括:2. The method according to claim 1, wherein if the target ECG detection only includes resting ECG detection, the ECG data includes the subject's age and resting ECG signal. , the reference feature includes a first resting reference feature; and analyzing the high-frequency components of the QRS wave complex in the ECG data according to the target ECG detection to obtain the corresponding reference feature includes: 分析所述静息心电信号中QRS波群的高频成分得到高频QRS包络曲线;Analyze the high-frequency components of the QRS wave complex in the resting ECG signal to obtain a high-frequency QRS envelope curve; 根据所述高频QRS包络曲线与所述年龄确定第一静息参考特征;所述第一静息参考特征包括静息阳性导联数量、静息临界导联数量、第一目标导联数量与第二目标导联数量;所述第一目标导联数量是指相应高频形态指数大于或等于第一指数阈值的静息导联的数量;所述第二目标导联数量是指相应均方根电压小于或等于第一电压阈值的静息导联的数量。The first resting reference feature is determined according to the high-frequency QRS envelope curve and the age; the first resting reference feature includes the number of resting positive leads, the number of resting critical leads, and the number of first target leads. and the second target lead number; the first target lead number refers to the number of resting leads whose corresponding high-frequency morphological index is greater than or equal to the first index threshold; the second target lead number refers to the corresponding average The number of resting leads whose root-square voltage is less than or equal to the first voltage threshold. 3.根据权利要求2所述的方法,其特征在于,所述参考特征还包括第二静息参考特征;所述按照所述目标心电检测对所述心电数据中QRS波群的高频成分进行分析得到相应参考特征,还包括:3. The method according to claim 2, wherein the reference feature further includes a second resting reference feature; and the high-frequency QRS wave complex in the ECG data is detected according to the target ECG. The components are analyzed to obtain corresponding reference characteristics, which also include: 根据所述高频QRS包络曲线与所述年龄确定第二静息参考特征;所述第二静息参考特征包括所述静息阳性导联数量、所述静息临界导联数量与所述第一目标导联数量;A second resting reference feature is determined according to the high-frequency QRS envelope curve and the age; the second resting reference feature includes the number of resting positive leads, the number of resting critical leads and the Number of first target leads; 所述根据所述参考特征确定心脏风险评估等级与心脏风险类型,包括:Determining the cardiac risk assessment level and cardiac risk type based on the reference characteristics includes: 根据所述第一静息参考特征确定第一风险评估等级;Determine a first risk assessment level based on the first resting reference characteristic; 根据所述第二静息参考特征确定第二风险评估等级;Determine a second risk assessment level based on the second resting reference characteristic; 根据所述第一风险评估等级与所述第二风险评估等级确定心脏风险评估等级与心脏风险类型。The cardiac risk assessment level and the cardiac risk type are determined according to the first risk assessment level and the second risk assessment level. 4.根据权利要求3所述的方法,其特征在于,所述第一静息参考特征还包括目标高频形态指数与目标均方根电压;所述第二静息参考特征还包括所述目标高频形态指数;所述目标高频形态指数为各静息导联对应的高频形态指数中的最大值;所述目标均方根电压为各静息导联对应的均方根电压中的最小值。4. The method according to claim 3, wherein the first resting reference feature further includes a target high-frequency morphological index and a target root mean square voltage; the second resting reference feature further includes the target High-frequency morphology index; the target high-frequency morphology index is the maximum value among the high-frequency morphology indexes corresponding to each resting lead; the target root-mean-square voltage is the root-mean-square voltage corresponding to each resting lead. minimum value. 5.根据权利要求1所述的方法,其特征在于,所述参考特征还包括第二静息参考特征与第二运动参考特征;所述按照所述目标心电检测对所述心电数据中QRS波群的高频成分进行分析得到相应参考特征,还包括:5. The method of claim 1, wherein the reference features further include a second resting reference feature and a second motion reference feature; The high-frequency components of the QRS wave complex are analyzed to obtain corresponding reference features, which also include: 根据所述高频QRS包络曲线与所述年龄确定第二静息参考特征;所述第二静息参考特征包括所述静息阳性导联数量、所述静息临界导联数量与所述第一目标导联数量;A second resting reference feature is determined according to the high-frequency QRS envelope curve and the age; the second resting reference feature includes the number of resting positive leads, the number of resting critical leads and the Number of first target leads; 根据所述高频QRS波形曲线、所述年龄与所述最大心率确定第二运动参考特征;所述第二运动参考特征包括所述运动阳性导联数量与所述运动临界导联数量;Determine a second motion reference feature according to the high-frequency QRS waveform curve, the age and the maximum heart rate; the second motion reference feature includes the number of motion positive leads and the number of motion critical leads; 所述根据所述参考特征确定心脏风险评估等级与心脏风险类型,包括:Determining the cardiac risk assessment level and cardiac risk type based on the reference characteristics includes: 根据所述第一静息参考特征确定第一风险评估等级;Determine a first risk assessment level based on the first resting reference characteristic; 根据所述第二静息参考特征与所述第二运动参考特征确定第二风险评估等级;Determine a second risk assessment level based on the second resting reference feature and the second motion reference feature; 根据所述第一运动参考特征确定第三风险评估等级;Determine a third risk assessment level based on the first motion reference characteristic; 根据所述第一风险评估等级、所述第二风险评估等级与所述第三风险评估等级确定心脏风险评估等级与心脏风险类型。The cardiac risk assessment level and cardiac risk type are determined according to the first risk assessment level, the second risk assessment level and the third risk assessment level. 6.根据权利要求5所述的方法,其特征在于,所述第一静息参考特征还包括目标高频形态指数与目标均方根电压;所述第二静息参考特征还包括所述目标高频形态指数;所述目标高频形态指数为各静息导联对应的高频形态指数中的最大值;所述目标均方根电压为各静息导联对应的均方根电压中的最小值;第一运动参考特征还包括各运动导联对应的第一振幅下降相对值与第二振幅下降相对值;所述第二运动参考特征还包括各运动导联对应的第二振幅下降相对值。6. The method of claim 5, wherein the first resting reference feature further includes a target high-frequency morphological index and a target root mean square voltage; the second resting reference feature further includes the target High-frequency morphology index; the target high-frequency morphology index is the maximum value among the high-frequency morphology indexes corresponding to each resting lead; the target root-mean-square voltage is the root-mean-square voltage corresponding to each resting lead. minimum value; the first motion reference feature also includes the first relative amplitude decrease value and the second relative amplitude decrease value corresponding to each motion lead; the second motion reference feature also includes the second relative amplitude decrease value corresponding to each motion lead. value. 7.根据权利要求1至6中任意一项所述的方法,其特征在于,所述方法还包括:7. The method according to any one of claims 1 to 6, characterized in that the method further includes: 根据所述心电数据按照所述心脏风险类型确定相应风险评估特征;Determine corresponding risk assessment characteristics according to the cardiac risk type according to the ECG data; 根据所述风险评估特征确定相应心脏风险类型的关注级别。The level of concern for the corresponding cardiac risk type is determined based on the risk assessment characteristics. 8.一种心脏风险评估装置,其特征在于,所述装置包括:8. A cardiac risk assessment device, characterized in that the device includes: 获取模块,用于获取与临床适应症相匹配的目标心电检测所对应的心电数据;所述临床适应症用于指示能否进行负荷运动心电检测;所述目标心电检测至少包括静息心电检测;The acquisition module is used to obtain the ECG data corresponding to the target ECG detection that matches the clinical indications; the clinical indications are used to indicate whether stress exercise ECG detection can be performed; the target ECG detection at least includes static ECG testing; 特征确定模块,用于按照所述目标心电检测对所述心电数据中QRS波群的高频成分进行分析得到相应参考特征;A feature determination module, configured to analyze the high-frequency components of the QRS wave complex in the ECG data according to the target ECG detection to obtain corresponding reference features; 风险评估模块,用于根据所述参考特征确定心脏风险评估等级与心脏风险类型;所述心脏风险评估等级作为对受测者进行分流的参考指标;所述心脏风险类型作为评估所述受测者的心脏可能存在的风险类型的参考指标。A risk assessment module, configured to determine a cardiac risk assessment level and a cardiac risk type based on the reference characteristics; the cardiac risk assessment level serves as a reference index for triaging a subject; and the cardiac risk type serves as a reference indicator for assessing the subject A reference indicator of the type of risk that may exist for your heart. 9.一种计算机设备,包括存储器和处理器,所述存储器存储有计算机程序,其特征在于,所述处理器执行所述计算机程序时实现权利要求1至7中任一项所述的方法的步骤。9. A computer device, comprising a memory and a processor, the memory stores a computer program, characterized in that when the processor executes the computer program, the method of any one of claims 1 to 7 is implemented. step. 10.一种计算机可读存储介质,其上存储有计算机程序,其特征在于,所述计算机程序被处理器执行时实现权利要求1至7中任一项所述的方法的步骤。10. A computer-readable storage medium with a computer program stored thereon, characterized in that when the computer program is executed by a processor, the steps of the method according to any one of claims 1 to 7 are implemented.
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