CN116570338B - Left auricle occluder and placement method - Google Patents

Abstract

The invention discloses a left auricle plugging device which comprises a plugging unit and a grapple unit, wherein the plugging unit can be contracted and expanded, when the plugging device is placed, the plugging unit is in a contracted state, and after the grapple unit is fixed on a comb muscle in a special form in a human left auricle, the plugging unit is expanded to plug the human left auricle. According to the left auricle plugging device, the grapple units are detachably connected with the plugging units, and the grapple units with proper specifications can be selected according to actual conditions so as to adapt to different patients, improve the flexibility and adaptability of the plugging device, and reduce the damage to the patients caused by placing the plugging device. Meanwhile, the grapple unit is fixed on the comb muscle in a special form in the left auricle of the human body, so that the placement stability of the left auricle occluder is improved, the situation that the left auricle occluder leaks or falls off is prevented, the occlusion reliability is improved, and meanwhile, the inner wall of the left auricle of the human body is prevented from being punctured and fixed. The invention also provides a placement method of the left auricle occluder.

Description

A kind of left atrial appendage occlusion device and placement method

Technical field

The present invention relates to the technical field of medical devices, and in particular to a left atrial appendage occluder and a placement method.

Background technique

For patients with atrial fibrillation or those with high CHA ₂ DS ₂ -VASc scores (atrial fibrillation stroke risk scores), LAA occluders are often used to seal the patient's LAA to isolate it from the left atrium and prevent LAA The detached thrombus enters the blood circulation and causes an embolism event. The left atrial appendage occluder is a cage-like or plug-like device composed of a metal stent and a polymer membrane. The metal structure of the device mainly includes an occluder disc and an occluder mesh. There are blocking membranes in both the blocking disk and the blocking net. The blocking disk has a cylindrical mesh structure, and the blocking film is fixed and covers the inner wall of the blocking disk. The blocking net has a round cake mesh structure, and the blocking film is fixed and covers the inner wall of the blocking net. The sealing disk and the sealing net are connected by connecting rods or brackets through the bases in their respective centers.

The blocking function of the left atrial appendage occluder is realized by the blocking disc, the blocking net, and the blocking membrane. The blocking disc fixes the position of the occluder and the inside of the left atrial appendage. The blocking net is located in the atrium. It is the structural basis for the atrial endothelial cells to endothelialize the occluder in the left atrium, and it also has a fixation effect. The joint action of the occlusion disk and the occlusion net enables the LAA occluder to be bidirectionally fixed at the opening of the LAA in the left atrium - the movement of the occluder into the LAA is hindered by the occluder net, and its movement into the left atrium is anchored. Fixed hook pulling. The occluding membrane made of polytetrafluoroethylene in the occluding disc and mesh allows the passage of red blood cells while preventing the dislodged thrombus from entering the left atrium from the left atrial appendage.

When the left atrial appendage occluder is not placed, it is stored in a folded umbrella shape in the delivery sheath. The occluder disc occluder mesh is made of nickel-titanium alloy and has malleability and memory. It can be expanded into a plug-like structure and mesh after release. shape structure.

During the placement of the left atrial appendage occluder, the delivery sheath transports the folded occluder from the left atrium into the left atrial appendage. The relative position of the top of the delivery sheath and the left atrial appendage is determined through the positioning ring under real-time angiography, and the delivery sheath is pushed deep into the left atrial appendage. The bottom end of the occluder is connected to the guide wire, and the delivery sheath is withdrawn at the same time to release the left atrial appendage occluder from the delivery sheath. The occlusion disc is deployed in the left atrial appendage, forming a plug-like structure. There are anchor hooks on the metal support rods of the structure. The surgeon pulls the guidewire occluder to make the anchor hooks on the occlusion disc penetrate into the inner wall of the left atrial appendage to achieve closure. device fixation. Continue to withdraw the delivery sheath, unfold the blocking net, and cover the left atrial appendage opening from the left atrium side. If the placement is not good and needs to be repositioned, push the delivery sheath forward so that the left atrial appendage occluder loses its support function under the pressure of the delivery sheath opening, and folds back into the delivery sheath in an umbrella shape to realize the recovery function for relocation. After successful placement, unscrew the guidewire, withdraw the delivery sheath, and complete the placement of the left atrial appendage occlusion device.

The structure of the human left atrial appendage is complex and diverse. The inner wall of the left atrial appendage has ravines composed of pectinate muscles. In the heart structure of some patients, there is a special shape of the pectinate muscle that is connected to the inner wall of the left atrial appendage at both ends and is not connected to the inner wall of the left atrial appendage in the middle. In the journal called HeartRhythm, an article was published in 2013: Anatomical characteristics of the leftatrial appendage in cardiogenic stroke with low CHADS ₂ scores (DOI: 10.1016/j.hrthm.2013.01.036). In the image at the end of the article, the label is The image of "H" reflects the influence of this special shape of pectinate muscle on the blood flow field in the left atrial appendage. This picture proves the existence of this physiological structure in the left atrial appendage, that is, the existence of a special shape of pectinate muscle. If the left atrial appendage occluder cannot fully fit the inner wall of the left atrial appendage due to the pectinate muscles during placement, there will be a gap between the occluder and the inner wall of the left atrial appendage, and there is a risk that the detached thrombus will enter the left atrium and enter the systemic blood vessels along with the blood. leading to embolic events in patients.

Although various optimizations have been made in the structural design, the structure of the left atrial appendage occluder has changed from a separate plug-like structure to a two-part structure consisting of a blocking disk and a blocking net, which further increases the success rate of blocking detached thrombi and optimizes The endothelialization process of the left atrium for the left atrial appendage occluder was analyzed. At present, when the left atrial appendage occluder is placed, in order to stably pierce the inner wall of the left atrial appendage with the anchor hook and achieve the effect of fixing the occluded disc, the surgeon needs to pull the left atrial appendage outward so that the overall placement position of the left atrial appendage occluder is at The left atrial appendage of the left atrium is biased toward the left atrium side. The blocking net should have been tightly fitted to cover the opening of the left atrial appendage. However, due to traction, the coverage was not tight, resulting in a gap between the blocking net and the atrial wall, causing leakage and possibly DRT (device-related thrombosis device-related thrombosis) occurs. At the same time, pulling the occlusion disc with force may cause the anchor hook on the occlusion disc to tear the inner wall of the left atrial appendage. If the placement is not good, the blocking disk needs to be retracted, the anchoring hook is inserted into the inner wall of the left atrial appendage again, and the process of "release, deployment, pulling, and insertion" is repeated, which may cause greater harm to the patient. The current left atrial appendage occluder can change the diameter of the occluder net and occluder disk. However, due to the complex and diverse structure of the human left atrial appendage, there is still the problem of poor adaptability, and the placement process is still easy to cause harm to the patient.

Therefore, how to change the current situation in the existing technology that the left atrial appendage occluder has poor adaptability and easily causes harm to patients has become an urgent problem for those skilled in the art to solve.

Contents of the invention

The purpose of the present invention is to provide a left atrial appendage occluder and a placement method to solve the above-mentioned problems existing in the prior art, improve the adaptability of the left atrial appendage occluder, and reduce the harm caused to patients by placing the occluder.

In order to achieve the above object, the present invention provides the following solutions: The present invention provides a left atrial appendage occluding device, including:

A blocking unit, the blocking unit can be contracted and expanded, and when expanded, the blocking unit can block the left atrial appendage of the human body;

The grapple unit is detachably connected to the blocking unit, and the grapple unit can be fixed on the special-shaped pectinate muscle in the left atrial appendage of the human body.

Preferably, the blocking unit includes a first blocking membrane, a stent assembly and a second blocking membrane, the first blocking membrane is connected to the second blocking membrane using the stent assembly, and the first blocking membrane The blocking film, the stent assembly and the second blocking film are all made of elastic material. In the free state, the first blocking film and the second blocking film are bowl-shaped structures, and The openings of both are arranged in a direction away from the bracket assembly.

Preferably, the stent assembly includes an inner stent wire, an inner stent base, an outer stent wire and an outer stent base. The inner stent base is located at the closing end of the first sealing membrane and is connected to each other. The inner stent wire One end is connected to the opening end of the first blocking film, and the other end is connected to the inner bracket base; the outer bracket base is located at the closing end of the second blocking membrane and the two are connected, and the outer bracket Wires connect the first blocking membrane and the outer stent base.

Preferably, the number of the inner stent wires and the outer stent wires is multiple, and the inner stent wires and the outer stent wires surround the axes of the first blocking film and the second blocking film. Evenly distributed in circumferential direction.

Preferably, the shape of the inner stent wire is consistent with the outline of the first blocking membrane; the outer stent wire is also connected to an auxiliary stent wire, and the auxiliary stent wire is arranged on two adjacent ones of the Between the outer stent wires, the auxiliary stent wires are X-shaped.

Preferably, the blocking unit further includes a blocking net, the blocking net cover is provided outside the second blocking film, and the shape of the blocking net matches the second blocking film, so The closing end of the blocking net is connected to the base of the outer bracket, and the blocking net is made of woven nickel-titanium alloy wire.

Preferably, both the inner stent base and the outer stent base can be detachably connected to the guide wire of the delivery sheath.

Preferably, the grapple unit includes a grapple base, a spring, a grapple rod and a shackle connected in sequence. The grapple base is detachably connected to the blocking unit, and the shackle can be hooked on the left atrial appendage of the human body. It is fixed on the special shape of the pectinate muscle inside.

Preferably, the shackles are annular structures with notches, the number of shackles is multiple, and the plurality of hooks are evenly distributed around the axis of the grab bar.

The present invention also provides a method for placing the above-mentioned left atrial appendage occluder, which puts the occluder unit in a contracted state, transports the left atrial appendage occluder into the left atrial appendage of the human body, and moves the grapple unit away from the occluder unit. One end of the blocking unit is fixed on the pectinate muscle of a special shape in the left atrial appendage of the human body, so that the blocking unit is deployed, and the blocking unit blocks the left atrial appendage of the human body.

Compared with the prior art, the present invention achieves the following technical effects:

In the left atrial appendage occluder of the present invention, the occluder unit can contract and expand. When the occluder is placed, the occluder unit is in a contracted state, and the grapple unit is fixed on the special-shaped pectinate muscle in the left atrial appendage of the human body. The blocking unit is deployed to block the human left atrial appendage. In the left atrial appendage occluder of the present invention, the grapple unit and the occluder unit are detachably connected. The grapple unit of appropriate specifications can be selected according to the actual situation to adapt to different patients, improve the flexibility and adaptability of the occluder, and reduce the cost of placing the occluder. The harm caused by the occluder to the patient. At the same time, the grapple unit of the present invention is fixed on the special-shaped pectinate muscle in the left atrial appendage of the human body. In the left atrial appendage of some patients, there is a special-shaped pectinate muscle. In the case of atrial fibrillation, the contraction function of the left atrial appendage disappears. , this type of pectinate muscle no longer has the contractile function, which is one of the reasons for the increased risk of thrombus formation in the left atrial appendage. However, the position of the pectinate muscle is relatively fixed, and because it is a muscle tissue, it has a certain toughness, and it can be used as a fixed left atrial appendage. The fixed point of the occluder improves the placement stability of the left atrial appendage occluder, prevents the left atrial appendage occluder from leaking or falling off, improves the reliability of the occluder, and the grapple unit is fixed in the left atrial appendage of the human body. The special shape of the pectinate muscle avoids puncturing and fixing the inner wall of the human left atrial appendage, thereby further reducing the harm caused to the patient by placing the left atrial appendage occluder.

The present invention also provides a method for placing the above-mentioned left atrial appendage occluder. The occluder unit is used to occlude the left atrial appendage. At the same time, the grapple unit is used to fix the special-shaped pectinate muscle in the left atrial appendage of the human body to avoid damage to the left atrial appendage. Puncture of the left atrial appendage endothelium reduces the complications of pericardial effusion and cardiac tamponade during closure surgery.

Description of the drawings

In order to explain the embodiments of the present invention or the technical solutions in the prior art more clearly, the drawings needed to be used in the embodiments will be briefly introduced below. Obviously, the drawings in the following description are only some of the drawings of the present invention. Embodiments, for those of ordinary skill in the art, other drawings can also be obtained based on these drawings without exerting creative efforts.

Figure 1 is a isometric view of the left atrial appendage occluder disclosed in an embodiment of the present invention;

Figure 2 is a front view of the left atrial appendage occluder disclosed in the embodiment of the present invention;

Figure 3 is a top view of the left atrial appendage occluder disclosed in the embodiment of the present invention;

Figure 4 is a side view of the left atrial appendage occluder disclosed in the embodiment of the present invention;

Figure 5 is a schematic structural diagram of the grapple unit of the left atrial appendage occluder disclosed in the embodiment of the present invention;

Figure 6 is a schematic diagram of the placement of the left atrial appendage occluder disclosed in the embodiment of the present invention.

Among them, 100 is the blocking unit and 200 is the grappling hook unit;

1 is the first blocking membrane, 2 is the stent component, 3 is the second blocking membrane, 4 is the inner stent wire, 5 is the inner stent base, 6 is the outer stent wire, 7 is the outer stent base, and 8 is the auxiliary stent wire. , 9 is the blocking net, 10 is the grapple base, 11 is the spring, 12 is the grapple rod, 13 is the shackle, 14 is the tie line, 15 is the delivery sheath, and 16 is the guide wire.

Detailed ways

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts fall within the scope of protection of the present invention.

The purpose of the present invention is to provide a left atrial appendage occluder and a placement method to solve the above-mentioned problems existing in the prior art, improve the adaptability of the left atrial appendage occluder, and reduce the harm caused to patients by placing the occluder.

In order to make the above objects, features and advantages of the present invention more obvious and understandable, the present invention will be described in further detail below with reference to the accompanying drawings and specific embodiments.

The present invention provides a left atrial appendage occluding device, which includes a occluding unit 100 and a grapple unit 200. The occluding unit 100 can be contracted and expanded, and when expanded, the occluding unit 100 can seal the human left atrial appendage; the grapple unit 200 and The blocking unit 100 is detachably connected, and the grapple unit 200 can be fixed on the special-shaped pectinate muscle in the left atrial appendage of the human body.

In the left atrial appendage occluder of the present invention, the occluder unit 100 can be contracted and expanded. When the occluder is placed, the occluder unit 100 is in a contracted state, and the grapple unit 200 is fixed in a special comb shape in the left atrial appendage of the human body. On the muscle, the blocking unit 100 is deployed to block the left atrial appendage of the human body. In the left atrial appendage occluder of the present invention, the grapple unit 200 and the occluder unit 100 are detachably connected. The grapple unit 200 of appropriate specifications can be selected according to the actual situation to adapt to different patients and improve the flexibility and adaptability of the occluder. Reduce the harm caused to the patient by placing the occluder. At the same time, the grapple unit 200 of the present invention is fixed on the special-shaped pectinate muscle in the left atrial appendage of the human body. In the left atrial appendage of some patients, there is a special-shaped pectinate muscle. In the case of atrial fibrillation, the left atrial appendage contraction function disappear, this type of pectinate muscle no longer has the contraction function, which is one of the reasons for the increased risk of thrombus formation in the left atrial appendage. However, the position of the pectinate muscle is relatively fixed, and because it is a muscle tissue, it has a certain toughness. As a fixed left atrial appendage, it has a certain toughness. The fixed point of the atrial appendage occluder improves the placement stability of the left atrial appendage occluder, prevents the left atrial appendage occluder from leaking or falling off, and improves the reliability of the occluder, and the grapple unit 200 is fixed on the left atrial appendage of the human body. The special shape of the pectinate muscle in the device avoids puncturing and fixing the inner wall of the human left atrial appendage, thereby further reducing the harm caused to the patient by placing the left atrial appendage occluder.

Specifically, the blocking unit 100 includes a first blocking membrane 1, a bracket assembly 2 and a second blocking membrane 3. The first blocking membrane 1 is connected to the second blocking membrane 3 using the bracket assembly 2. The first blocking membrane 1. The stent assembly 2 and the second blocking membrane 3 are both made of elastic material, so that the blocking unit 100 can be contracted to facilitate the use of the delivery sheath 15 to transport the left atrial appendage occluder. In the free state, the first blocking membrane 1 and the second occluding membrane 3 are both bowl-shaped structures, and the openings of both are set in a direction away from the stent assembly 2. After the occluder is delivered in place, the grapple unit 200 is fixed in the special left atrial appendage of the human body. After the pectinate muscle is attached, the delivery sheath 15 is removed, and the blocking unit 100 automatically expands under the action of elasticity to block the left atrial appendage of the human body.

More specifically, the stent assembly 2 includes an inner stent wire 4, an inner stent base 5, an outer stent wire 6 and an outer stent base 7. The inner stent base 5 is located at the closing end of the first sealing membrane 1 and is connected to each other. The inner stent wire One end of 4 is connected to the open end of the first blocking membrane 1, and the other end is connected to the inner bracket base 5. The inner bracket wire 4 is used to support the first blocking membrane 1; the outer bracket base 7 is located at the closing end of the second blocking membrane 3 The first blocking membrane 1 is connected to the outer bracket base 7 by using the outer bracket wire 6 to improve the overall structural strength of the blocking device.

In order to further enhance the structural stability of the occluder, there are multiple inner stent wires 4 and multiple outer stent wires 6. The inner stent wires 4 and the outer stent wires 6 surround the first blocking membrane 1 and the second blocking membrane. 3 is evenly distributed in the circumferential direction to ensure the structural strength of the blocking unit 100 and at the same time improve the force uniformity between the first blocking membrane 1 and the outer bracket base 7 .

In this specific embodiment, the shape of the inner stent wire 4 is consistent with the outline of the first blocking membrane 1 to enhance the support stability of the inner stent wire 4 to the first blocking membrane 1 and thereby improve the performance of the occluder. Blocking reliability. In order to further improve the support stability and reliability of the bracket assembly 2, the outer bracket wire 6 is also connected to an auxiliary bracket wire 8. The auxiliary bracket wire 8 is arranged between two adjacent outer bracket wires 6. The auxiliary bracket wire 8 is X Shape, one end of the auxiliary stent wire 8 is connected to the end of the outer stent wire 6 close to the first blocking membrane 1, the other end of the auxiliary stent wire 8 is connected to the end of the outer stent wire 6 close to the outer stent base 7, the auxiliary stent wire 8 is connected to The outer stent wires 6 cooperate to form a support grid, which ensures that the stent assembly 2 can shrink with the first blocking film 1 and the second blocking film 3 while ensuring the structural stability of the blocking unit 100 in the unfolded state. It should also be noted here that in order to enhance the firmness of the connection between the outer stent wire 6 and the first blocking membrane 1 , the edge of the first blocking membrane 1 is fixed on the outer stent wire 6 using tie wires 14 to ensure a firm connection. At the same time, the tie wires 14 can also be used to enhance the supporting effect of the stent assembly 2 on the first blocking membrane 1 .

At the same time, the blocking unit 100 also includes a blocking net 9. The blocking net 9 is covered outside the second blocking film 3. The shape of the blocking net 9 matches the second blocking film 3. The blocking net 9 can The second blocking membrane 3 provides stable support to ensure that the first blocking membrane 1 and the second blocking membrane 3 can cooperate to block the human left atrial appendage and avoid leakage. The closing end of the blocking net 9 is connected to the outer stent base 7 , in this specific embodiment, the blocking net 9 is made of woven nickel-titanium alloy wire, so that the blocking net 9 can shrink and expand with the second blocking film 3. The blocking net 9 has ductility and memory at the same time. , when the second blocking film 3 is unfolded, it can be unfolded to form a network structure to support the second blocking film 3 . In other specific embodiments of the present invention, other materials can also be selected to make the blocking net 9 to meet different working conditions and further improve the flexibility and adaptability of the blocking device.

It should also be noted that both the inner stent base 5 and the outer stent base 7 can be detachably connected to the guide wire 16 of the delivery sheath 15, so that the guide wire 16 of the delivery sheath 15 can be used to drive the occluder to the delivery position smoothly and complete the process. Release of the occluder. In this specific embodiment, both the inner bracket base 5 and the outer bracket base 7 can be threadedly connected to the guide wire 16, and the connection is tight and easy to disassemble and assemble. When the guide wire 16 is threadedly connected to the inner bracket base 5, the guide wire 16 passes through The outer bracket base 7 is passed to further improve the convenience of operation.

In addition, the grapple unit 200 includes a grapple base 10, a spring 11, a grapple 12 and a shackle 13 connected in sequence. The grapple base 10 is detachably connected to the blocking unit 100, and the shackle 13 can be hooked on a special (the hook 13 is hooked on the middle part of the pectinate muscle of a special shape that is not connected to the inner wall of the left atrial appendage) to achieve fixation. In this specific embodiment, the grapple base 10 and the inner stent base 5 are detachable. Connection, a spring 11 is provided between the grapple base 10 and the grapple rod 12. The spring 11 can play a buffering role when the fixed hook ring 13 is operated. In practical applications, other types of elastic parts can also be selected according to actual operation needs.

It should also be emphasized that the shackle 13 is an annular structure with a gap, so that the shackle 13 can hook the pectinate muscle of a special shape, which facilitates operation while ensuring the grabbing stability as much as possible. In this specific embodiment, , the corresponding central angle of the hook 13 is 270° to ensure reliable grasping, and the gap size of the hook 13 can be adjusted according to the size of the special shape of the pectinate muscle. The number of shackles 13 is one or more, and multiple shackles 13 are evenly distributed around the axis of the grab rod 12. In order to meet different fixing requirements, multiple grab hook units 200 can be provided, and the shackles of each grab hook unit 200 The numbers 13 are different, and the grapple base 10 is threadedly connected to the inner stent base 5 to facilitate replacement and improve the flexibility and adaptability of the left atrial appendage occluder.

Further, the present invention also provides a method for placing the above-mentioned left atrial appendage occluder, which puts the occluder unit 100 in a contracted state, transports the left atrial appendage occluder into the left atrial appendage of the human body, and moves the grapple unit 200 away from the occluder. One end of the unit 100 is fixed on the special-shaped pectinate muscle in the left atrial appendage of the human body, so that the blocking unit 100 is unfolded, and the blocking unit 100 blocks the left atrial appendage of the human body. The blocking unit 100 is used to block the left atrial appendage, and at the same time, The grapple unit 200 is fixed on the special-shaped pectinate muscle in the left atrial appendage of the human body, which avoids penetration of the left atrial appendage endothelium and reduces the occurrence of complications such as pericardial effusion and cardiac tamponade during closure surgery.

When placing the left atrial appendage occluder of the present invention, please refer to Figure 6. The delivery sheath 15 transports the contracted left atrial appendage occluder into the left atrial appendage, and the guide wire 16 is pushed to remove the contracted left atrial appendage occluder from the delivery sheath 15. Push it out, first expose the grapple unit 200, manipulate the guide wire 16 and the delivery sheath 15, so that the grapple ring 13 is hooked on the special shape of the pectinate muscle (the hook ring 13 is hooked on the special shape of the pectinate muscle and is not in contact with the left The middle part where the inner wall of the atrial appendage is connected) to achieve fixation; after the grasping is completed, keep the guide wire 16 motionless and withdraw (move the delivery sheath 15 away from the left atrial appendage) the delivery sheath 15 to expose the external stent wire 6 and the blocking net 9. Rotate the guide wire 16 to separate the guide wire 16 from the inner stent base 5. Tighten the guide wire 16 and the outer stent base 7 to connect them. Then withdraw the delivery sheath 15 to the outer stent base 7. At this time, the delivery sheath 15 No force is exerted on the contracted left atrial appendage occluder, but the occluder cannot be deployed under the constraints of the left atrial appendage orifice; continue to withdraw the guide wire 16 to completely withdraw the occluder net 9 from the left atrial appendage, and the occluder net 9 and The second blocking membrane 3 expands under the action of its own elasticity. At the same time, the stent component 2 loses the restraint of the blocking net 9 and opens completely. The six outer stent wires 6 pull the first blocking membrane 1 to expand toward the inner wall of the left atrial appendage. At the same time, they give the inner stent wire 4 a pulling force to expand, assisting the stent wire 8 to expand. Support the outer stent wire 6; the inner stent wire 4 is stretched to all sides under its own elasticity, and the outer stent wire 6 and the edge of the first sealing membrane 1 are closely attached to the inner wall of the left atrial appendage, and at the same time, the direction of the left atrial appendage sealing device is applied. The internal tension of the left atrial appendage causes the blocking net 9 to closely fit on one side of the atrium to block the left atrial appendage opening; the guide wire 16 is rotated to separate the guide wire 16 from the outer stent base 7 to complete the placement of the left atrial appendage blocking device. It should be explained here that the delivery sheath 15 and the guide wire 16 are common methods used by those skilled in the art, and will not be described again here.

The left atrial appendage occluder of the present invention can pull the left atrial appendage occluder from the inside of the left atrial appendage, and the pulling force acts on the occluder net 9 so that it can closely fit and cover the left atrial appendage orifice on the left atrium side. The hook unit 200 is fixed on the special-shaped pectinate muscle in the left atrial appendage of the human body, so that the left atrial appendage occluder can be fixed more stably and prevent the left atrial appendage occluder from leaking or falling off; it can also target special-shaped patients. Due to individual differences in pectinate muscles, different grapple units 200 can be replaced to enhance the fitting effect of the left atrial appendage occluder and achieve tighter occludement.

Glossary:

Special shape of pectinate muscle: There is a pectinate muscle on the inner wall of the left atrial appendage of the human body. In the left atrial appendage of some people, the two ends of the pectinate muscle are connected to the inner wall of the left atrial appendage, but the middle part is not connected to the inner wall of the left atrial appendage. This will This kind of pectinate muscle whose middle part is not connected to the inner wall of the left atrial appendage is called a pectinate muscle with a special shape. There is a gap between the middle part of the pectinate muscle with a special shape and the inner wall of the left atrial appendage.

Specific examples are used in the present invention to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core idea; at the same time, for those of ordinary skill in the art, based on this The idea of the invention will be subject to change in the specific implementation and scope of application. In summary, the contents of this description should not be construed as limitations of the present invention.

Claims (7)

1. A left atrial appendage occlusion device, characterized by comprising: A blocking unit, the blocking unit can be contracted and expanded, and when expanded, the blocking unit can block the left atrial appendage of the human body; A grapple unit, the grapple unit is detachably connected to the blocking unit, and the grapple unit can be fixed on the special-shaped pectinate muscle in the left atrial appendage of the human body; The blocking unit includes a first blocking membrane, a stent assembly and a second blocking membrane. The first blocking membrane is connected to the second blocking membrane using the stent assembly. The first blocking membrane , the stent assembly and the second blocking film are made of elastic material, in the free state, the first blocking film and the second blocking film are bowl-shaped structures, and both The openings are all arranged in a direction away from the bracket assembly; The stent assembly includes an inner stent wire, an inner stent base, an outer stent wire and an outer stent base. The inner stent base is located at the closing end of the first blocking film and is connected to each other. One end of the inner stent wire is connected to The opening end of the first blocking film is connected, and the other end is connected to the inner bracket base; the outer bracket base is located at the closing end of the second blocking membrane and the two are connected, and the outer bracket wire is connected to the The first sealing film and the outer bracket base. 2. The left atrial appendage occluder according to claim 1, characterized in that: the number of the inner stent wire and the outer stent wire is multiple, and the inner stent wire and the outer stent wire are wound around The axes of the first blocking film and the second blocking film are evenly distributed in the circumferential direction. 3. The left atrial appendage occlusion device according to claim 1, characterized in that: the shape of the inner stent wire is consistent with the outline of the first blocking membrane; the outer stent wire is also connected to an auxiliary stent. The auxiliary stent wire is arranged between two adjacent outer stent wires, and the auxiliary stent wire is X-shaped. 4. The left atrial appendage occlusion device according to claim 1, characterized in that: the occlusion unit further includes a occlusion net, and the occlusion net cover is located outside the second occlusion membrane, and the The shape of the blocking net matches the second blocking film. The closing end of the blocking net is connected to the base of the outer bracket. The blocking net is made of woven nickel-titanium alloy wire. 5. The left atrial appendage occluder according to any one of claims 1 to 4, characterized in that: both the inner stent base and the outer stent base can be detachably connected to the guide wire of the delivery sheath. 6. The left atrial appendage occluder according to any one of claims 1 to 4, characterized in that: the grapple unit includes a grapple base, a spring, a grapple rod and a shackle connected in sequence, and the grapple base Detachably connected to the blocking unit, the hook can be hooked on the special-shaped pectinate muscle in the left atrial appendage of the human body and fixed. 7. The left atrial appendage occluder according to claim 6, characterized in that: the shackle is an annular structure with a gap, the number of the shackles is multiple, and the plurality of hooks surround the grasping device. The axis of the rod is uniformly distributed around the circumference.