CN115919504B - Split type single embedded branch tectorial membrane support - Google Patents

Abstract

The present application relates to a split-type single embedded branch covered stent, which includes a main frame with at least one fenestration structure; one end of the embedded stent is sealed and fixed to the fenestration structure, so that the fenestration structure passes through the embedded stent and the fenestration structure. The connecting cavity of the main stent is connected; the branch stent is detachably inserted into the embedded stent through the fenestration structure; the branch stent includes the branch film and the branch skeleton assembly fixed on the branch film. Along the radial direction of the branch stent, the branch film Including a first layer of membrane and a second layer of membrane, the first layer of membrane is located inside the connecting cavity of the branch stent, the second layer of membrane is located outside the branch stent, and the branch skeleton assembly is fixed between the first layer of membrane and the second layer of membrane , the proximal end and the far end of the branch coating are respectively integrally formed with folded sections, and the folded sections are fixed to the inner peripheral wall of the branch coating. The application has the effect of reducing the damage and stimulation of the branch stent to the LSA distal vessel wall in the cardiac cycle, and improving the long-term patency rate of the branch artery.

Description

Split single embedded branch covered stent

technical field

The present application relates to the field of medical devices, in particular to a split-type single-embedded branch covered stent.

Background technique

With the improvement of endovascular technology and advances in material science, Thoracic Endovascular Aortic Artery Repair (TEVAR) has become the first choice for the treatment of type B aortic dissection. Artery (Left Subclavian Artery, LSA)) lesions due to insufficient or unhealthy proximal anchoring area, conventional TEVAR needs to occlude the left clavicle artery to prolong the proximal anchoring area, but left upper limb ischemia, subclavian artery stealing may occur after surgery Therefore, it is very important to preserve or reconstruct the left clavicle artery when performing TEVAR surgery for Stanford type B dissection.

Common surgical methods for left clavicle artery reconstruction include hybrid surgery, parallel stent technique, fenestration technique, and branch stent technique. Hybrid surgery is effective, but compared with total endovascular surgery, it still has the disadvantages of large trauma and long operation time. Parallel stent technology is relatively simple and easy to operate, but because there is a gutter between the two stents, the probability of type I endoleak increases, and the interaction force between the stents and between the stent and the aortic wall makes reverse tearing of the dissection and There is an increased risk of parallel stent occlusion. The fenestration technique is mainly to reserve on the artificial vascular membrane of the stent, design a side hole or in-situ fenestration according to the specific situation before the operation, and reserve the blood supply of the branch arteries through the side hole after the stent is released. The disadvantage is that the positioning is not accurate and the technical difficulty is high. , there is a risk of failure, an increase in the chance of infection during the reconstruction of the stent, or a risk of affecting the long-term patency rate of the LSA stent, the structural stability of the main stent and/or the service life. The branch stent technology is more in line with the physiological anatomy. While reducing the risk of type I endoleak, it also reduces the risk of type III endoleak. It can also effectively isolate lesions with breaches located in LSA. It is expected to become the first choice for reconstructing LSA in the future.

Branch stent technology provides an integrated branched aortic stent-graft technology to treat patients with Stanford type B dissection. It uses corresponding interventional instruments to radially compress the stent-graft and deliver it to the lesion position to release it. Restore the stent graft to the predetermined shape, thereby separating the dissection breach or enlarged cavity of the human blood vessel, reshaping the true lumen of the blood vessel, and restoring the blood flow to the correct direction, thereby achieving the therapeutic effect. In order to ensure the blood supply of the branch arteries, the branch arteries and the stent graft are usually connected by a branch stent, that is, the branch stent and the stent graft are integrated, and the branch stent is released in the branch artery, thereby ensuring the blood supply of the branch artery. Effect. However, branch stents can cause damage to the inner wall of the artery when pulled into the branch artery.

Contents of the invention

In order to improve the problem that the branch stent of the existing covered stent will cause damage to the inner wall of the artery when it is pulled into the branch artery, the present application provides a split-type single-embedded branch covered stent.

The application provides a split-type single embedded branch covered stent, including a main body stent, the main body stent is a tubular structure with openings at both ends, the main body stent encloses a communication cavity for communicating with the target blood vessel, the main body The bracket is provided with at least one window structure;

An embedded bracket, the embedded bracket is a tubular structure with openings at both ends, and one end of the embedded bracket is sealed and fixed to the window structure, so that the window structure passes through the embedded bracket and the main body The communication cavity of the stent communicates; and

A branch stent, the branch stent is a tubular structure with openings at both ends, the branch stent encloses a connecting cavity for communicating with the branch artery, and the branch stent is detachably plugged into the embedded In the stent, the connection cavity of the branch stent communicates with the communication cavity;

The branch stent includes a branch film and a branch skeleton assembly fixed to the branch film. Along the radial direction of the branch stent, the branch film includes a first layer of film and a second layer of film. The first A layer of membrane is located inside the connecting cavity of the branch stent, the second layer of membrane is located outside the branch stent, and the branch skeleton assembly is fixed between the first layer of membrane and the second layer of membrane In between, the proximal end and the distal end of the branch coating are respectively integrally formed with folded sections, and the folded sections are fixed to the inner peripheral wall of the branch coating.

In some other embodiments, the main body stent includes a tubular membrane, a bare stent, and a plurality of supporting skeletons, both the bare stent and the supporting framework are in a ring structure, and the bare stent is fixed on the tubular membrane A plurality of the support skeletons are located at the distal end side of the bare stent, and a plurality of the support skeletons are arranged and fixed in sequence along the axial direction of the tubular covering; the bare stent and the support skeleton both include A plurality of supporting rods connected successively at included angles, along the circumferential direction of the main body bracket, two adjacent included angles are respectively crests and troughs, and the crests are closer to the center of the main body bracket than the troughs Proximal end: at least part of the crests, troughs and the support rods of the supporting frame are fitted and fixed on the peripheral wall of the tubular covering, at least part of the crests of the supporting frame are in contact with the The tubular coverings have gaps therebetween and are separable from said tubular coverings to form free zones, said free zones having an axial length of at least 2.5-4 mm.

In some other embodiments, the plurality of supporting skeletons include an adherent skeleton, a bundle diameter skeleton, an auxiliary skeleton and a distal skeleton arranged in sequence from the proximal end to the distal end of the tubular membrane, and the adherent skeleton and The beam diameter skeletons are all located on the proximal side of the fenestration structure, the auxiliary skeleton and the distal skeleton are both located on the distal side of the fenestration structure; the troughs of the bare stent are fixed on the The tubular covering, the crest of the bare stent and the struts of the bare stent at least partially extend beyond the proximal end of the tubular covering; the axial length of each strut on the adherent skeleton are all the same; there are multiple beam diameter skeletons, and the axial lengths of the supporting rods on at least one of the beam diameter skeletons are the same; the axial lengths of the supporting rods on the distal end skeleton are the same;

There are at least two auxiliary frames, the troughs of two adjacent auxiliary frames are axially opposite, and the peaks of two adjacent auxiliary frames are axially opposite; along the main body In the circumferential direction of the bracket, the two adjacent peaks on the auxiliary frame include high waves and low waves, and the high waves are closer to the proximal end of the main body bracket than the low waves; Among the peaks, the high waves and the low waves are arranged alternately along the circumferential direction of the main body bracket.

In some other embodiments, the trough of the bare stent is fixed with a plurality of suture loops by dense sutures to fix the trough of the bare stent to the tubular graft, and the support rod is fixed by suturing. At least one suture coil is fixed by thread suture to fix the support rod of the bare stent to the tubular graft, and the suture coil on the support rod of the bare stent is connected to the The suture coils on the troughs are closely adjacent; the troughs of the bare stent and the struts are fixed to the axial length of the tubular graft by the suture coils to form an anchoring zone, and the anchoring The axial length of the region is at least 3-5 mm, and the axial length of the anchoring region is the overlapping length of the bare stent and the adherent framework in the axial direction.

In some other embodiments, the plurality of supporting frames further include at least one first reinforcing frame, and at least one of the first reinforcing frames is located at the distal side of the fenestration structure; the beam diameter frame also includes at least one The second reinforcing frame, at least one second reinforcing frame is located on the distal side of at least one second full fixed frame, the first reinforcing frame and the second reinforcing frame are arranged adjacent to each other in the axial direction, so The first reinforcing frame and the second reinforcing frame are respectively located on both sides of the window structure in the axial direction; at least one of the supporting rods on the first reinforcing frame has the same axial length, and at least one of the The axial lengths of the supporting rods on the second reinforcing frame are the same, and the peaks, the troughs and the supporting rods on at least one of the first reinforcing frames are all attached and fixed to the peripheral wall of the tubular coating , the trough on the first reinforcing skeleton is axially opposite to the crest on the second reinforcing skeleton.

In some other embodiments, the flexible beam diameter member is a ring structure, and any at least two points on the ring of the beam diameter member are fixed to the main body bracket to form two fixing points, so that the flexible The bundle diameter member forms at least two flexible rings; alternatively, the flexible bundle diameter member includes at least two flexible rings, and one end of the flexible ring in the length direction is fixed to at least one of the tubular membrane and the supporting frame to Form a fixed site;

Along the circumferential direction of the main body bracket, the ends of the two flexible rings away from the fixing point can overlap each other to form a wire loop for the bundle diameter guide wire to pass through, and the length direction of the flexible ring can be along the The circumferential arrangement of the main body bracket, the length direction of at least two flexible rings can surround the circumferential direction of the main body bracket so that the main body bracket can be radially compressed.

In some other embodiments, the fixing position is a fixing sleeve, and the fixing sleeve fixes the connecting bone on the branch rod corresponding to each of the first wave-shaped rings; or, the at least part of the fixing position Each of the first wave-shaped rings is formed by helically winding the branch rod where the connecting bone is located on the connecting bone.

In the split-type single embedded branch covered stent provided by the present application, the branched stent is inserted into the embedded stent through the fenestrated structure, so that the branched stent communicates with the communicating cavity, so that the blood flow flowing through the communicating cavity is introduced into the branched stent , to reconstruct branch arteries, the detachable plug-in cooperation between the branch stent and the main body stent can reduce the damage and stimulation of the branch stent to the LSA distal vessel wall during the cardiac cycle, thereby ensuring the long-term patency of the branch artery. The structural design of the branch stent has a significant impact on the long-term patency of the branch artery. The covering of the branch is two layers of membrane, and the branch skeleton component is located between the two layers of membrane, which can further reduce the impact of the branch stent on the LSA during the cardiac cycle. Injury stimulation of the distal vessel wall. During the process of radial compression of the branch stent in the interventional device, or in the process of releasing the branch stent from the interventional device to the branch artery, the friction between the branch stent and the interventional device, the pulsation of the target vessel and the branch artery itself, inappropriate The release and positioning of the main body stent and the branch stent have different degrees of separation tests on the two layers of membranous material, that is, the two layers of membranous material have the risk of being at least partially separated from each other, resulting in the risk of occlusion of the branch stent and affecting the branch stent. long-term patency. The setting of at least two turning sections is beneficial to improve the friction force between the proximal end and the distal end of the first layer of film and the second layer of film being impacted by high-flow blood flow, and the friction between the branch stent and the interventional instrument during the compression and release process 1. The impact of the target blood vessel and the branch artery's own pulsation on the branch stent or the problem of at least partial separation due to inappropriate operation reduces the risk of occlusion of the branch stent and improves the long-term patency rate of the branch stent.

Description of drawings

Fig. 1 is a schematic diagram of the structure of a split type single embedded branch covered stent.

Fig. 2 is a structural schematic diagram of another viewing angle of the split-type single embedded branch stent-graft.

Fig. 3 is a schematic structural view of the main body stent (the flexible bundle diameter member is not shown).

Fig. 4 is a plane expanded view of the main body bracket (the built-in bracket is not shown).

Fig. 5 is a plan development view of another possible embodiment of the main body bracket.

Fig. 6 is a structural schematic diagram of the cooperation of the flexible bundle diameter member and the circumscribed bundle diameter guide wire to radially compress part of the main body stent.

Fig. 7 is a schematic diagram of the structure of the embedded stent.

Fig. 8 is a schematic structural diagram of a branch bracket.

Fig. 9 is a structural schematic diagram of another possible fixing method for connecting the bone and the first wave-shaped ring.

Fig. 10 is a schematic diagram of a scene where a split type single embedded branch covered stent is used for reconstruction of the aortic arch.

Fig. 11 is a schematic diagram of another exemplary structure of the main body bracket.

FIG. 12 is a schematic diagram of an enlarged structure at point A in FIG. 11 .

Explanation of reference numerals: 1. main body support; 10. tubular coating; 20. bare support; 201. anchoring area; 30. support frame; 3001. support rod; 3002. peak; ;32, beam diameter frame; 321, first fully fixed frame; 322, second fully fixed frame; 3221, high wave; 3222, low wave; 323, second reinforced frame; 33, first reinforced frame; 34, auxiliary frame ; 341, free zone; 35, distal skeleton; 36, reinforced part; 361, first support rod; 362, second support rod; 363, reinforced trough; 364, first wall-attached trough; 365, second wall-attached trough; 366, first avoidance peak; 367, second avoidance peak; 40, flexible beam diameter member; 401, flexible ring; 402, fixed position; 403, wire ring; 404, beam diameter guide wire; 50, Suture coil; 60, connecting node; 70, developing mark; 2, embedded stent; 21, embedded membrane; 22, embedded skeleton; 3, branch bracket; 301, branch membrane; 302, support section; 303 , flexible segment; 304, adherent segment; 305, folded segment; 306, supporting bone ring; 3061, first wave ring; 3062, second wave ring; 3063, connecting bone; 3064, branch rod; 3065, fixed sleeve ;307, flexible bone ring; 371, wave-shaped unit; 372, unit rod; 308, adherent bone ring; 4, fenestration structure; 5, aortic arch; 6, lesser curvature; 7, left clavicle artery; 8, tumor cavity .

Detailed ways

The following will clearly and completely describe the technical solutions in the embodiments of the application with reference to the accompanying drawings in the embodiments of the application. Apparently, the described embodiments are only part of the embodiments of the application, not all of them. Based on the implementation manners in this application, all other implementation manners obtained by persons of ordinary skill in the art without creative efforts shall fall within the scope of protection of this application.

For the field of interventional medical devices, the proximal end refers to the end of the stent close to the human heart after the interventional treatment, and the distal end refers to the end of the stent away from the human heart after the interventional treatment. The direction of the rotation center axis of objects such as cylinders and tubes is the axial direction, and the direction perpendicular to the axial direction is the radial direction. The circumferential direction refers to the "circumferential direction", that is, the direction around the axis of the cylinder, tube, etc. (perpendicular to the axis and perpendicular to the radius of the section). "Circumferential", "axial", and "radial" together constitute three orthogonal directions of cylindrical coordinates. Circumferential length refers to the extension length of a structure or element along the circumferential direction of a column, tube, etc. Axial length refers to the extension length of a structure or element along the axial direction of a column, tube, etc. This description is only for the convenience of expression, and does not constitute a limitation to the present application. The structure below refers to the expanded structure of the split-type single-embedded branch stent-graft.

In order to improve the problem that the branch stent of the existing stent-graft will cause damage to the inner wall of the artery when it is pulled into the branch artery, the first embodiment of the present application provides a split-type single-embedded branch stent-graft, which can be applied to blood vessels In this method, endoluminal isolation can be performed to isolate the lesion area in the lumen or the dissection breach. For example, a split-type single-embedded branch covered stent can be used to isolate the arterial dissection breach or aneurysm in the lumen of the blood vessel. It can be understood that the blood vessel may be the aortic arch, thoracic aorta, abdominal aorta, etc. Those of ordinary skill in the art should know that the use of blood vessels for illustration is only used as an example and not a limitation of the present application. The solutions of the present application are applicable to various human or animal lumens, such as digestive tract lumens.

Please refer to FIG. 1 and FIG. 2 . FIG. 1 is a schematic structural diagram of a split-type single embedded branch stent-graft, and FIG. 2 is a structural schematic diagram of a split-type single embedded branch stent-graft from another perspective. The split-type single embedded branch stent-graft includes a main body stent 1, an embedded stent 2 fixed on the inner wall of the main body stent 1, and a branch stent 3 detachably connected to the main body stent 1, and the branch stent 3 is used for reconstructing branch arteries. The main body stent 1 is a tubular structure with two ends open, and the main body stent 1 encloses a communicating cavity (not shown in the figure) for communicating with a target blood vessel. The main body bracket 1 is provided with at least one window opening structure 4, and the window opening structure 4 may be circular, oval or other irregular shapes. The embedded bracket 2 is a tubular structure with two ends open, and one end of the embedded bracket 2 is sealed and fixed to the window structure 4 so that the window structure 4 communicates with the communication cavity of the main body bracket 1 through the embedded bracket 2 . The branch stent 3 is a tubular structure with two ends open, and the branch stent 3 encloses a connecting cavity (not shown in the figure) for communicating with the branch artery. The branch stent 3 is plugged into the embedded stent 2 through the fenestration structure 4, so that the branch stent 3 communicates with the communicating cavity, so that the blood flowing through the communicating cavity is introduced into the branch stent 3, and the branch artery is reconstructed. The detachable plug-in cooperation between the branch stent 3 and the main body stent 1 can reduce the damage and stimulation of the branch stent 3 to the LSA distal vessel wall during the cardiac cycle, thereby ensuring the long-term patency of the branch artery.

Please refer to FIG. 3 and FIG. 4 together. FIG. 3 is a schematic structural view of the main body stent 1 (the flexible beam diameter member 40 is not shown), and FIG. 4 is a planar development view of the main body stent 1 (the embedded bracket 2 is not shown). The main body stent 1 includes a tubular covering 10 , a bare stent 20 , a plurality of supporting frameworks 30 and a plurality of groups of flexible bundle diameter members 40 . Both the bare stent 20 and the support frame 30 are ring-shaped structures, the bare stent 20 is fixed on the proximal end of the tubular membrane 10, a plurality of support frameworks 30 are located at the distal side of the bare stent 20, and the plurality of support frameworks 30 are arranged along the tubular membrane 10. The axial direction is arranged in sequence and fixed. Both the bare bracket 20 and the supporting frame 30 include a plurality of supporting rods 3001 connected in sequence at angles. Along the circumferential direction of the main body bracket 1, the two adjacent angles are respectively a peak 3002 and a valley 3003, and the peak 3002 is compared with the valley 3003. Closer to the proximal end of the main body bracket 1. The bare stent 20 and the supporting frame 30 can be fixed on the tubular covering 10 by suturing, sticking, stamping, sticking, setting or hot pressing. A plurality of groups of flexible beam diameter members 40 are all located at the proximal side of the fenestration structure 4, and the flexible beam diameter members 40 are used to radially compress the local body stent 1 located at the proximal end side of the fenestration structure 4, that is, the proximal end of the fenestration structure 4 The region from the end edge to the proximal edge of the main body stent 1 can be radially compressed by the flexible beam diameter member 40 to be in a radially compressed state, so that after the main body stent 1 enters the target blood vessel, the at least partially radially compressed main body stent 1 can still be in the target blood vessel. Axial movement or circumferential rotation in the blood vessel facilitates precise adjustment of the position of the fenestration structure 4 , so that the fenestration structure 4 is better aligned with the root opening of the branch artery, and the positioning accuracy of the fenestration structure 4 is improved.

A plurality of supporting frames 30 includes an adherent frame 31, a beam diameter frame 32, at least one first reinforcing frame 33, an auxiliary frame 34 and a distal frame 35, an adherent frame 31, a beam diameter frame 32, and at least one first reinforcing frame 33 , the auxiliary frame 34 and the distal frame 35 are arranged and fixed sequentially along the proximal end of the tubular membrane 10 to the distal end of the tubular membrane 10 . The sticking frame 31 and beam diameter frame 32 are located at the proximal side of the fenestration structure 4 , and the auxiliary frame 34 , the distal frame 35 and at least one first reinforcing frame 33 are all located at the distal side of the fenestration structure 4 .

The trough 3003 of the bare stent 20 is fixed on the tubular covering 10, the crest 3002 of the bare stent 20 and the support rod 3001 of the bare stent 20 at least partially extend out of the proximal end of the tubular covering 10, that is, at least part of the support rod 3001 of the bare stent 20 The peak 3002 of the partial and bare stent 20 is not covered by the tubular coating 10, in other words, along the axial direction of the support rod 3001, the support rod 3001 is at least partially not covered by the tubular coating 10, and the peak 3002 of the bare stent 20 Not covered by the tubular membrane 10 . The trough 3003 of the bare stent 20 is fixed with a plurality of suture coils 50 by dense sutures to fix the trough 3003 of the bare stent 20 to the proximal end of the tubular covering 10 (that is, the multiple suture coils 50 are closely adjacent to each other), supporting The rod 3001 is sutured with at least one suture coil 50 to fix the support rod 3001 of the bare stent 20 to the tubular covering 10, and the suture coil 50 on the support rod 3001 is connected with the suture coil 50 on the valley 3003 of the bare stent 20 closely adjacent. The trough 3003 and the support rod 3001 of the bare stent 20 are fixed to the axial length of the tubular graft 10 through the suture coil 50 to form an anchoring region 201, and the axial length of the anchoring region 201 is at least 3-5mm, that is, the bare stent 20 The axial length covered by the tubular membrane 10 is 3-5 mm, and the part of the bare stent 20 covered by the tubular membrane 10 is fixed to the tubular membrane 10 by suturing coils 50 . In some other embodiments, the exemplary formation method of the suture coil 50 may be as follows: taking the support frame 30 fixed on the outer peripheral wall of the tubular membrane 10 as an example, the two sides in the length direction of the support rod 3001 are named as the first side and the first side respectively. On the second side, one end of the suture is fixed on the outer peripheral wall of the tubular covering 10, step S1, the other end of the suture is inserted into the inner peripheral wall of the tubular covering 10 along the first side of the support rod 3001, step S2, followed by The suture thread passes from the inner peripheral wall of the tubular covering 10 to the outer peripheral wall of the tubular covering 10 along the second side of the support rod 3001, step S3, then the suture wraps around the support rod 3001 and passes through the first side of the support rod 3001 Inserted into the inner peripheral wall of the tubular covering film 10, a suture coil 50 with a substantially ring-shaped structure is formed after the steps S1-S3 are completed. Finally, steps S1 to S3 are repeated along the shape trend of the support frame 30 to fix the bare stent 20 and the support frame 30 to the tubular membrane 10 .

The crests 3002, troughs 3003, and support rods 3001 of the adherent frame 31, beam diameter frame 32, at least one first reinforcement frame 33, and the distal frame 35 are all fixed to the tubular membrane 10 by sutures, such as the crests 3002 and troughs 3003 All of them are fixed with a plurality of suture coils 50 (that is, the multiple suture coils 50 are closely adjacent to each other) through intensive suture with suture threads, and at least one suture coil 50 is arranged at intervals on the support rod 3001, so that the suture threads will adhere to the wall skeleton 31, beam diameter The frame 32, at least one first reinforcing frame 33, and the distal frame 35 are fitted and fixed on the tubular covering 10, so that the wall-attached frame 31, beam diameter frame 32, at least one first reinforcing frame 33, and the distal frame 35 are almost completely Fitting the tubular film 10 for fixation not only improves the radial support force of the adherent frame 31, the beam diameter frame 32, at least one first reinforcement frame 33 and the distal frame 35, but also helps to prevent the beam diameter frame 32 from being hooked to the flexible frame. The bundle diameter member 40 facilitates the disengagement of the flexible bundle diameter member 40 to release the main body stent 1 , so that the main body stent 1 self-expands to return to a predetermined shape smoothly.

At least one wall-attached framework 31 is located on the proximal side of the fenestration structure 4 . The waveform trend of the adherent framework 31 is consistent with that of the bare stent 20, that is, the peak 3002 of the adherent framework 31 is opposite to the peak 3002 of the bare stent 20 in the axial direction, and the wave trough 3003 of the first fully fixed framework 321 is opposite to that of the bare stent 20 in the axial direction. The troughs 3003 of the stent 20 are opposite in the axial direction, so that the crests 3002 of the adherent framework 31 can be located in the area between two adjacent support rods 3001 of the bare stent 20, which is beneficial to avoid the proximal end of the tubular membrane 10 from being placed on the implantation target. After the blood vessel, because the anatomical structure of the target blood vessel is relatively curved, the proximal end of the tubular membrane 10 is easy to wrinkle, which is beneficial to reduce the occurrence of type Ia endoleak. The point where the strut 3001 on the bare stent 20 intersects with the proximal edge of the tubular covering 10 and the contact point between the crest 3002 of the adherent skeleton 31 and the tubular covering 10 are both named connection nodes 60, the anchor of the bare stent 20 The setting of the axial length of the fixed area 201 makes the arrangement of the connecting nodes 60 along the circumferential direction of the tubular coating 10 more reasonable, and avoids too large a difference in the circumferential distance between any two adjacent connecting nodes 60 , that is, the setting of the axial length of the anchoring area 201 makes the arrangement of the connecting nodes 60 more uniform along the circumferential direction of the tubular membrane 10, which is beneficial to further avoid The problem of wrinkling occurs, so as to better prevent internal leakage. The crest 3002 of the adherent framework 31 is fixed at the position near the proximal edge of the tubular covering 10, so that the axial length of the anchoring area 201 is approximately the overlapping length of the bare stent 20 and the adherent framework 31 in the axial direction (ie, the length of the adherent The distance between the crest 3002 of the skeleton 31 and the proximal edge of the tubular covering 10 is allowed to have an error of ±1.5mm), the axial length of the anchoring area 201 of the bare stent 20 is set so that the main body stent 1 radially shrinks or radially During the expansion process, the waveform trend of the adherent skeleton 31 is consistent with the waveform trend of the bare stent 20, which is beneficial to avoid deformation of the proximal end of the main body stent 1 during radial contraction or radial self-expansion, so that the main body stent 1 and the The adherence between the blood vessel walls is better, further improving the effect of preventing endoleak. In the adherent framework 31, each support rod 3001 has the same axial length along the tubular covering 10, so as to enhance the radial support force of the proximal end of the main body stent 1, thereby helping to reduce the risk of blood flow due to high flow after the main body stent 1 is implanted in the target blood vessel. The risk of displacement due to the impact of the current.

Beam diameter frame 32 includes at least one first fully fixed frame 321, at least one second fully fixed frame 322 and at least one second reinforced frame 323, at least one first fully fixed frame 321, at least one second fully fixed frame 322 and at least one A second reinforcing frame 323 is arranged and fixed sequentially along the proximal end to the distal end of the tubular membrane 10 . At least one first full fixation frame 321 can be located at the proximal side of the fenestration structure 4 . At least one first fully fixed framework 321 is located at the distal side of at least one wall-attached framework 31, and the wavelength of the first fully fixed framework 321 is smaller than the wavelength of other supporting frameworks 30, in other words, at least one first fully fixed framework 321 Compared with the waveforms of other supporting frameworks 30, the waveform of the main body stent 1 is denser, so that the proximal end of the main body stent 1 fits the blood vessel wall better, and reduces the risk of type Ia endoleak. The axial lengths of the support rods 3001 on at least one first fully fixed frame 321 along the main body stent 1 are the same, so as to further increase the radial support force at the proximal end of the main body stent 1, thereby helping to reduce the number of implants of the main body stent 1 into the target blood vessel. There is a risk of subsequent displacement due to the impact of high flow blood flow.

At least one second full fixation frame 322 is located at the proximal side of the fenestration structure 4 . The axial lengths of the support rods 3001 on at least one third fixed frame are different. Specifically, along the circumferential direction of the main body bracket 1, two adjacent crests 3002 include a high wave 3221 and a low wave 3222. Compared with the low wave, the high wave 3221 3222 is closer to the proximal end of the body stent 1 . Along the circumferential direction of the main body stent 1, the high wave 3221 and the low wave 3222 are arranged alternately, which is beneficial to reduce the straightening force of the proximal end of the main body stent 1, improve the flexibility of the proximal end of the main body stent 1, and make the proximal end of the main body stent 1 better. Fitting the anatomical structure of the curved blood vessel, it is beneficial to reduce the risk of type Ia endoleak.

In other embodiments, for example, please refer to FIG. 5 , which is a plan development view of another possible embodiment of the main body bracket 1 . The setting of the second full fixed frame 322 can also be omitted.

In this embodiment, the first reinforcing frame 33 and the second reinforcing frame 323 are arranged adjacent to each other in the axial direction, and the first reinforcing frame 33 and the second reinforcing frame 323 are located on both sides of the window structure 4 in the axial direction, namely The first reinforcing frame 33 is located at the distal side of the fenestration structure 4 , and the second reinforcing frame 323 is located at the proximal end side of the fenestration structure 4 . The axial lengths of the supporting rods 3001 on the first reinforcing frame 33 are the same, and the axial lengths of the supporting rods 3001 on the second reinforcing frame 323 are the same. The setting of the first reinforcement frame 33 and the second reinforcement frame 323 is used to enhance the radial support force around the fenestration structure 4, so that the fenestration structure 4 can be more fully in contact with the blood vessel wall, which is beneficial to improve the fenestration structure 4 Extrusion deformation (such as extrusion of calcified plaque, irregular blood vessel section, etc. on the main body stent 1). For the peaks 3002 and troughs 3003 on the first reinforcement skeleton 33 and the second reinforcement skeleton 323, the peaks 3002 on the first reinforcement skeleton 33 and the troughs 3003 on the second reinforcement skeleton 323 are axially opposite, and the first reinforcement skeleton 33 The trough 3003 on the top and the crest 3002 on the second reinforcing frame 323 are opposite in the axial direction, which helps to improve the problem of axial shortening of the part of the main body bracket 1 close to the window structure 4, and fully ensures that the window structure 4 is Returning to the predetermined form from the compressed state, at the same time, more sufficient space can be reserved for the window structure 4, which further fully ensures that the window structure 4 returns to the predetermined form from the radially compressed state.

In other embodiments, the axial length of the first reinforcing skeleton 33 may also be different, and the axial length of the second reinforcing skeleton 323 may also be different, that is, along the circumferential direction of the main body bracket 1, the first reinforcing skeleton 33 and the two adjacent crests 3002 on the second reinforcing frame 323 include a high wave 3221 and a low wave 3222 , and the high wave 3221 is closer to the proximal end of the tubular covering 10 than the low wave 3222 . Along the circumferential direction of the main body stent 1 , high waves 3221 and low waves 3222 are arranged alternately to further improve the flexibility of the proximal end of the main body stent 1 and improve the bird's beak effect.

According to the exemplary embodiment of the present application, in some exemplary embodiments, the setting of the second reinforcing frame 323 can also be omitted, so that the window structure 4 is located between at least one first full fixed frame 321 and the first reinforcing frame 33 .

The auxiliary frame 34 is provided with at least two, and the axial lengths of the support rods 3001 on the at least two auxiliary frames 34 are different, that is, along the circumferential direction of the main frame 1, two adjacent peaks 3002 on the auxiliary frame 34 include The high wave 3221 and the low wave 3222, the high wave 3221 is closer to the proximal end of the tubular graft 10 than the low wave 3222. Along the circumferential direction of the tubular membrane 10, high waves 3221 and low waves 3222 are arranged alternately. The high wave 3221 on the auxiliary framework 34 near the proximal end of the tubular membrane 10 is axially opposite to the low wave 3222 on the auxiliary framework 34 near the distal end of the tubular membrane 10 , and on the auxiliary framework 34 near the proximal end of the tubular membrane 10 The trough 3003 of the trough is opposite to the trough 3003 on the auxiliary frame 34 near the distal end of the tubular membrane 10 in the axial direction, so that the waveform trends of at least two auxiliary frames 34 are approximately the same.

The low wave 3222, the wave trough 3003 and the support rod 3001 of the auxiliary frame 34 are all fixed to the tubular covering 10 by sutures. The suture coils 50 are closely adjacent to each other), and at least one suture coil 50 is arranged at intervals on the support rod 3001 , so that the suture thread can suture and fix the auxiliary framework 34 to the tubular graft 10 . There is a gap between the high wave 3221 of the auxiliary frame 34 and the tubular covering 10 and the high wave 3221 of the auxiliary frame 34 can be separated from the tubular covering 10 to form a free area 341, that is, the high wave 3221 of the auxiliary frame 34 does not need to be fixed to the tubular covering 10 by sutures. The covering film 10, or the high wave 3221 of the auxiliary bracket does not need to be fixed on the tubular covering film 10 by sticking, punching, sticking, setting or hot pressing, so that the high wave 3221 of the auxiliary frame 34 is lower than the low wave of the auxiliary frame 34. 3222 has more room for deformation. The axial length of the free zone 341 is 2.5-4 mm, which ensures that the high wave 3221 of the auxiliary frame 34 has sufficient space for movement.

After the main body stent 1 is implanted into a curved target vessel, for example, after the main body stent 1 is implanted into the aortic arch 5, in order to adapt to the arched portion of the aortic arch 5, the main body stent 1 is close to the lesser curved side 6 of the vessel (see Figure 10). If one side needs to be adaptively bent, then the crests 3002 and troughs 3003 of the supporting frame 30 on the main frame 1 can approach each other in the axial direction, the alternate arrangement of high waves 3221 and low waves 3222 on the auxiliary frame 34 and the free area 341 of the high waves 3221 It is set so that the side of the auxiliary frame 34 close to the lesser curvature of the blood vessel 6 has a larger deformation space, that is, the support rods 3001 of two adjacent auxiliary frames 34 near the side of the lesser curvature of the blood vessel 6 can have more axial Deformation to increase the axial overlap length, at the same time, the high wave 3221 can be folded in the axial direction with the axially adjacent support frame 30 in a direction away from the central axis of the main body bracket 1, and the free area 341 of the high wave 3221 is set to drive the adjacent wave trough 3003 is folded in the axial direction with the axially adjacent support frame 30 in the direction close to the central axis of the main body stent 1, so that the side of the main body stent 1 close to the lesser curved side 6 of the blood vessel fits the curved curve of the blood vessel more closely, reducing the internal Leakage occurs. The greater the degree of arching of the target blood vessel, the greater the degree of axial deformation of the support rod 3001 on the side of the auxiliary frame 34 near the lesser curvature side 6 of the blood vessel.

There are at least two distal skeletons 35 , and at least two distal skeletons 35 are arranged in sequence along the axial direction of the tubular membrane 10 . The axial lengths of the support rods 3001 on the distal frame 35 are the same to increase the radial support force of the distal end of the main body stent 1, which is beneficial to improve the problem that the main body stent 1 is prone to displacement after being implanted in the target blood vessel. The distal end of the tubular covering film 10 is provided with at least one developing mark 70, and the developing mark 70 is located at the proximal end or the proximal end side of at least two distal skeletons 35 close to the distal end of the tubular covering film 10, that is, the developing mark 70 can be fixed On the distal skeleton 35, so that the development mark 70 is located at the proximal end of at least two distal skeletons 35 close to the distal port of the tubular film 10; the development mark 70 can also be fixed on the tubular film 10, so that the development mark 70 is located on the proximal side of at least two distal skeletons 35 near the distal port of the tubular graft 10 . The axial length of the visualized marker 70 and the distal edge of the tubular covering 10 is at least 30-50 mm. The developing mark 70 is used to indicate the position where another external support is plugged into the main support 1 , so that the external support and the main support 1 have sufficient overlapping axial lengths to provide sufficient anchoring length for the external support. The proximal end of the tubular covering 10 can also be fixed with at least one developing mark 70 for indicating the proximal position of the main body stent 1; the distal end of the tubular covering 10 can also be fixed with at least one developing mark 70 for indicating the main body stent 1 in the remote position. A plurality of developing marks 70 may also be fixed on the tubular film 10 around the circumference of the window structure 4 . In some other embodiments, there are four developing marks 70 around the window opening structure 4 in the circumferential direction, two of which are located on both sides of the window opening structure 4 along the axial direction of the main body bracket 1, and the other two developing marks 70 are located on both sides of the window opening structure 4 along the circumferential direction of the main body support 1 . The two development marks 70 on both sides of the fenestration structure 4 in the axial direction facilitate the alignment of the fenestration structure 4 with the edge of the root opening of the branch artery to the maximum extent, and it is convenient for the operator to judge the release completion degree of the fenestration structure 4, that is, to judge the opening Whether the window structure 4 is released to the maximum diameter; the two developing marks 70 on both sides of the window structure 4 are convenient for the operator to judge the coincidence of the two developing marks 70 after the main body support 1 is released. The two developing marks 70 do not coincide, and the operator can adjust the position of the main frame 1 again to adjust the position of the window structure 4 until the two developing marks 70 on the 4 circumference of the window structure overlap, so as to better ensure the opening The window structure 4 more completely coincides with the root opening of the branch artery, which ensures the precise positioning of the release of the branch stent 3 and significantly reduces the difficulty of operation during the operation.

The material of the developing mark 70 can be made of materials with good X-ray opacity, strong corrosion resistance, and good biocompatibility, and can be materials such as gold, platinum, tantalum, osmium, rhenium, tungsten, iridium, rhodium, or these materials alloy. It can be understood that the development mark 70 can also be understood as having a development material at the corresponding position of the corresponding distal end skeleton 35 or the tubular coating 10; The distal frame 35 or the fenestration structure 4 is respectively provided with a developing mark 70 , and the developing mark 70 is arranged around at least part of the distal frame 35 or the fenestration structure 4 .

Please refer to FIG. 4 and FIG. 6 in conjunction. FIG. 6 is a structural schematic diagram of the flexible bundle diameter member 40 cooperating with the circumscribed bundle diameter guide wire 404 to radially compress part of the main body stent 1 . The flexible bundle diameter member 40 is an annular structure, and any two points on the ring of the flexible bundle diameter member 40 are fixed to the support frame 30 to form two fixed points 402 (for example, by suturing, sticking, stamping, sticking, setting or hot pressing to form a fixing point 402 ), so that the flexible beam path member 40 forms at least two flexible rings 401 . The two fixing points 402 can be roughly coincident, so that the length direction of the flexible ring 401 can be arranged along the circumferential direction of the tubular membrane 10 . The two fixing points 402 may not coincide. For example, the two fixing points 402 may be spaced at a certain distance in the circumferential direction, at a certain distance in the axial direction, or at the same time in both the circumferential direction and the axial direction, so that The length direction of at least part of the flexible ring 401 is arranged along the circumferential direction of the tubular membrane 10 . In this embodiment, at least two fixed points 402 on the flexible beam diameter member 40 can be roughly overlapped to form coincident fixed points, and the multiple coincident fixed points formed by multiple groups of flexible beam diameter members 40 are roughly along the axial direction of the main body stent 1 The directions are aligned and extended. It can be understood that, in other embodiments, at least two flexible rings 401 can also be formed independently, instead of being separated from the same ring structure by setting at least two fixing points 402, for example, the flexible beam path member 40 includes at least two A flexible ring 401 , one end of the flexible ring 401 in the length direction is fixed to at least one of the tubular membrane 10 and the supporting frame 30 to form a fixing point 402 .

Multiple groups of flexible bundle diameter members 40 are arranged sequentially from the proximal end to the distal end of the tubular covering 10 , and the multiple groups of flexible bundle diameter members 40 are located on the proximal side of the fenestration structure 4 . For the same flexible beam path member 40, the ends of at least two flexible rings 401 away from the fixing point 402 are approached to each other along the circumferential direction of the main body bracket 1 until the ends of at least two flexible rings 401 away from the fixing point 402 can overlap each other to A wire loop 403 is formed for the guide wire 404 to pass through. The length direction of the flexible ring 401 can be arranged along the circumferential direction of the main body stent 1, and the length direction of at least two flexible rings 401 can surround the circumferential direction of the main body stent 1. The main body support 1 can be radially compressed. A plurality of wire loops 403 formed by multiple sets of flexible beam diameter members 40 are arranged and extended along the axial direction of the main body stent 1, and a bundle of diameter guide wires 404 are sequentially passed through each wire loop 403 along the axial direction of the main body stent 1, so that each At least two flexible rings 401 on a flexible bundle diameter member 40 can form a ring surrounding the main body stent 1 along the circumference of the main body stent 1, and the bundle diameter guide wire 404 plays a role in maintaining the ring, so that the main body Part of the axial length of the stent 1 is in a state of radial compression. After the main body stent 1 is implanted in the target blood vessel, the radially compressed main body stent 1 can still move axially or rotate circumferentially in the target blood vessel, so that it is convenient to precisely adjust the position of the fenestration structure 4, so that the fenestration structure 4 is better in harmony with the target blood vessel. The root openings of the branch arteries are aligned to improve the positioning accuracy of the fenestrated structure 4 .

Along the axial direction of the main body stent 1, at least one wave trough 3003 of the bare stent 20 is provided with a flexible beam diameter member 40, and at least one wave valley 3003 of the wall-attached skeleton 31 is provided with a flexible beam diameter member 40, and each beam diameter skeleton 32 is adjacent The at least one wave trough 3003 and the at least one wave crest 3002 are both provided with a flexible beam path member 40 . In other words, along the axial direction of the main body stent 1, the coincident fixed points of multiple sets of flexible beam diameter members 40 are located at least one trough 3003 of the bare stent 20, at least one trough 3003 of the adherent skeleton 31, and the first fully fixed skeleton. At least one crest 3002 and at least one trough 3003 adjacent to 321, at least one high wave 3221 and at least one trough 3003 adjacent to the second full fixed skeleton 322, and at least one crest 3002 and at least one adjacent trough 3003 on the second reinforced skeleton 323 One wave trough 3003. Compared with setting the coincident fixed point on the support rod 3001, setting the coincident fixed point on the adjacent wave peak 3002 and wave trough 3003 of the support frame 30 is beneficial to improve the radial compression of the main body bracket 1 after it is assembled in the interventional instrument. And the problem that the trough 3003 is tilted away from the central axis of the main body stent 1, thereby reducing the friction between the proximal end of the main body stent 1 and the inner wall of the interventional device, so that the proximal end of the main body stent 1 can be more smoothly separated from the interventional device and Released in target blood vessels. Along the axial direction of the main body stent 1, each overlapping fixed point is located on the similar peaks 3002 and troughs 3003 on each support frame 30, so that the multiple overlapping fixed points formed by multiple groups of flexible beam diameter members 40 are roughly along the axis of the main body stent 1. Arrange and extend in the direction.

It can be understood that if the main body bracket 1 can omit the second full fixed frame 322 and/or the second reinforced frame 323 , then the flexible beam diameter member 40 on the second fully fixed frame 322 and/or the second reinforced frame 323 is correspondingly omitted.

Please refer to FIG. 4 and FIG. 7 together. FIG. 7 is a schematic structural diagram of the embedded bracket 2 . The proximal end of the embedded bracket 2 is sealed and fixed to the fenestration structure 4 , so that the fenestration structure 4 communicates with the communication cavity through the embedded bracket 2 . The distal end of the embedded stent 2 extends toward the distal end of the main body stent 1, so as to facilitate the guide wire approach during the intracavitary interventional therapy and achieve a more ideal effect of the intracavitary interventional therapy. The embedded stent 2 includes an embedded membrane 21 and a plurality of embedded skeletons 22 , the embedded membrane 21 has a tubular structure, and the plurality of embedded skeletons 22 are arranged in sequence along the axial direction of the embedded membrane 21 . The distal port of the embedded film 21 is oblique, so that the side of the distal port of the embedded film 21 closer to the central axis of the main body stent 1 is closer than the side of the distal port of the embedded film 21 away from the central axis of the main body stent 1 Close to the proximal end of the main frame 1. The distal port of the embedded film 21 is designed with an oblique opening, which is beneficial to avoid excessive concentration of stress on the distal port of the embedded film 21, which may easily lead to the radial compression of the embedded stent 2 at the distal port of the embedded stent 2. Difficulty returning from self-expansion to a predetermined configuration. The embedded frame 22 is an open-loop structure, and the open ring opening of the embedded frame 22 is located on the side of the embedded coating 21 close to the inner wall of the main body stent 1 . The embedded framework 22 of the open-loop structure is beneficial to reduce the radial dimension of the main body stent 1 , so that the main body stent 1 can be released from the interventional device more smoothly.

The branch stent 3 is inserted into the embedded stent 2, so that the branch stent 3 communicates with the communicating cavity, so that the blood flowing through the communicating cavity is introduced into the branch stent 3, and the branch artery is reconstructed. The structural design of branch stent 3 has a significant impact on the long-term patency rate of branch arteries. Branch stent 3 technology provides an integrated branched aortic stent-graft technology to treat patients with Stanford type B dissection, but it may be due to high The impact of flow and blood flow, the wide range of pulsation of the vessel wall, the incorrect release and positioning of the main body stent 1 and the branch stent 3, or the irregular shape of the blood vessel section, etc., the structural limitations of the branch stent 3 itself are difficult to ensure the distance of the branch stent 3. In the long-term patency rate, the branch stent 3 may have the risk of occlusion, and it is difficult to guarantee the medium and long-term efficacy of interventional therapy. In the later stage, it may be necessary to place a bare stent 20 in the branch stent 3 for branch artery intervention to ensure the patency rate of the branch stent 3 , increasing the risk of complications.

In order to improve the problem that the long-term patency of the branch stent 3 is difficult to guarantee after the branch stent 3 is inserted into the main body stent 1 , different structural designs are adopted for different regions of the branch stent 3 along the axial direction of the branch stent 3 .

Please refer to FIG. 1 and FIG. 8 in conjunction. FIG. 8 is a schematic structural diagram of the branch bracket 3 . The branch stent 3 includes a branch covering film 301 and a branch skeleton assembly fixed to the branch covering film 301 . Along the radial direction of the branch stent 3, the branch coating 301 includes a first layer of film and a second layer of film (not shown in the figure), the first layer of film is located inside the connecting cavity of the branch stent 3, and the second layer of film is located inside the branch stent 3. On the outside of the stent 3 , the first layer of membrane is used for contacting with the blood flow, and the second layer of membrane is used for contacting with the blood vessel wall. The branch skeleton assembly is fixed between the first layer of film and the second layer of film, for example, the branch skeleton assembly can be fixed between the first layer of film and the second layer of film by means of heat and pressure.

Along the axial direction of the branch stent 3, the branch stent 3 includes a support section 302, a flexible section 303 and a wall-adhering section 304 connected in sequence from the proximal end to the distal end. Tapered design. It can be understood that the support segment 302 and the wall-adhering segment 304 are equal-diameter structures, relative to the flexible segment 303, in the actual production process, an error of ±10% is allowed, or, the support segment 302 and the wall-adhering segment 304 are designed With a small taper design, the supporting section 302 and the wall-adhering section 304 may not be completely isometric structures. The radial dimension of the support section 302 is greater than the radial dimension of the wall-adhering section 304 , and the radial dimension of the support section 302 is greater than the radial dimension of the embedded stent 2 . The radial dimension of the proximal end of the flexible segment 303 is greater than the radial dimension of the distal end of the flexible segment 303 , the proximal end of the flexible segment 303 is connected to the supporting segment 302 , and the distal end of the flexible segment 303 is connected to the adherent segment 304 .

The branch stent 3 also includes a turn-over section 305, the turn-over section 305 is provided with at least two sections, the at least two turn-over sections 305 are respectively located at the proximal end and the distal end of the branch coating 301, the turn-over section 305 is located in the connecting cavity, and The folded section 305 is fixed on the inner peripheral wall of the branch coating 301 , for example, the folded section 305 can be fixed to the inner peripheral wall of the branch coating 301 by means of sewing, pasting, stamping, pasting, embedding or hot pressing. The folded section 305 is formed by turning the proximal end and the distal end of the branch coating 301 into the connecting cavity, that is, at least one folded section 305 is integrally formed with the proximal end of the branch coating 301, and at least one folded section 305 is integrated with the branch membrane 301. The distal end of the covering film 301 is integrally formed. Since the branch coating 301 includes a first layer of film and a second layer of film, the branch coating 301 is two layers of membranes, and the branch skeleton assembly is located between the two layers of membranes, the branch stent 3 is radially compressed on the interventional instrument During the process, or when the branch stent 3 is separated from the interventional device to be released in the branch artery, the friction between the branch stent 3 and the interventional device, the pulsation of the target vessel and the branch artery itself, improper main body stent 1 and branch The release and positioning of the stent 3 all have different degrees of separation tests on the two layers of membranous matter, that is, the two layers of membranous matter have the risk of being at least partially separated from each other, resulting in the risk of occlusion of the branch stent 3 and affecting the distance of the branch stent 3. Period patency. The setting of at least two turning sections 305 is beneficial to improve the impact between the proximal end and the distal end of the first layer of film and the second layer of film and the impact of high-flow blood flow, the compression and release of the branch stent 3 and the interventional instrument. The impact of the friction force, the pulsation of the target blood vessel and the branch artery itself on the branch stent 3 or the problem of at least partial separation due to improper operation can reduce the risk of occlusion of the branch stent 3 and improve the long-term patency rate of the branch stent 3 . The axial length of the folded section 305 is 1-5 mm.

The branch skeleton assembly includes a supporting bone ring 306, a flexible bone ring 307 and a wall-attached bone ring 308 arranged in sequence along the axial direction of the branch bracket 3, the supporting bone ring 306 is located at the supporting segment 302, and the flexible bone ring 307 extends from at least part of the supporting segment 302, The flexible segment 303 and at least part of the adherent segment 304 extend sequentially, and the adherent bone ring 308 is located in the adherent segment 304 .

The supporting bone ring 306 includes a plurality of first wave-shaped rings 3061, at least one second wave-shaped ring 3062 and a connecting bone 3063. The plurality of first wave-shaped rings 3061 and at least one second wave-shaped ring 3062 are arranged in sequence along the axial direction of the branch bracket 3, The second wave ring 3062 is located at the distal side of the first wave ring 3061 , in other words, the first wave ring 3061 is closer to the proximal end of the branch stent 3 than the second wave ring 3062 . The connecting bone 3063 connects the plurality of first wave rings 3061 together. Both the first wave ring 3061 and the second wave ring 3062 include a plurality of branch rods 3064 which are successively connected at angles. It is closer to the proximal end of the branch stent 3 than the trough 3003 . Each first wave ring 3061 is provided with at least one fixing position fixed to the connecting bone 3063 so that the connecting bone 3063 connects the plurality of first wave rings 3061 in the axial direction. The fixing position is located on the branch bar 3064 of each first wave ring 3061 . The fixing position can be formed by suturing, sticking, punching, sticking, setting, welding or hot pressing. In this embodiment, the fixing position is a fixing sleeve 3065, and the fixing sleeve 3065 fixes the connecting bone 3063 on each first On the branch rod 3064 on the wave ring 3061. Along the axial direction of the branch bracket 3, the connecting bone 3063 extends along the adjacent support rods 3001 connecting two first wave-shaped rings 3061, so that the connecting bone 3063 is an inclined linear shape extending from the proximal end to the distal end of the support segment 302. . The setting of the connecting bone 3063 is beneficial to improve the shortening of the branch stent 3 due to the friction of the interventional instrument, the pulsation of the blood vessel, the impact of the blood flow, etc., or reduce the extent of the shortening, and at the same time strengthen the support section 302. The effect of radial support force. The connecting bone 3063 is set in an inclined linear shape, which is beneficial to reduce the friction between the connecting bone 3063 and the interventional instrument bracket or the radial compression and self-expansion of the branch bracket 3 to return to the predetermined shape. The risk of a second coat.

According to an exemplary embodiment of the present application, in other implementation manners, please refer to FIG. 9, for example, which is a structural schematic diagram of another possible fixing method between the connecting bone 3063 and the first waveform ring 3061 (only part of the first waveform is shown ring 3061 and partially connecting bone 3063). At least part of the fixed position is formed by helically winding the branch rod 3064 where the connecting bone 3063 is located on each first wave-shaped ring 3061 around the connecting bone 3063, that is, the branch rod 3064 where the fixed position is located on each first wave-shaped ring 3061 can be spirally wound. Winding on the connecting bone 3063 enables the connecting bone 3063 to more stably connect multiple first wave-shaped rings 3061 together, which is beneficial to further improve the problem of shortening of the branch stent 3 or further reduce the degree of shortening. The branch rod 3064 where the fixing position is located on each first wave-shaped ring 3061 can be helically wound on the connecting bone 3063, which also has the effect of reducing the number of fixing positions, for example, only retaining the two ends of the connecting bone 3063 in the length direction The fixing sleeve 3065 and the reduction in the number of fixing positions can reduce the friction between the branch bracket 3 and the interventional device, reduce the risk that the fixing sleeve 3065 may break the branch covering film 301, and reduce the radial size of the interventional device. It can be understood that, on the basis of spiral winding, other fixing methods such as sewing, cladding, punching, sticking, setting, welding or hot pressing can also be superimposed.

The flexible bone ring 307 includes a plurality of wave-shaped units 371 , and the flexible bone ring 307 is a tubular structure formed by connecting the wave-shaped units 371 end-to-end and continuously helically arranged along the outer periphery of the first layer of membrane. The wave unit 371 includes a plurality of unit rods 372 connected in sequence at angles. Along the circumferential direction of the branch bracket 3, the two adjacent angles are respectively a peak 3002 and a valley 3003. The peak 3002 is closer to the branch bracket 3 than the valley 3003. the proximal end. A branch rod 3064 on the second wave ring 3062 is provided with a fixing position, and the fixing position on the second wave ring 3062 fixes the end of the flexible bone ring 307 close to the proximal end of the branch bracket 3 on the second wave ring 3062, which is beneficial to The structural stability of the flexible bone ring 307 in the axial direction of the branch bracket 3 is improved.

The structure of the adherent bone ring 308 is the same as that of the supporting bone ring 306 , and will not be repeated here. It can be understood that the structure of the adherent bone ring 308 is the same as that of the supporting bone ring 306 , but the number of the first wave ring 3061 and the second wave ring 3062 may be different. For the adherent bone ring 308, a plurality of first wave-shaped rings 3061 and at least one second wave-shaped ring 3062 of the adherent bone ring 308 are arranged in sequence along the axial direction of the branch bracket 3, and the second wave-shaped ring 3062 of the adherent bone ring 308 is located at The proximal side of the first wave-shaped ring 3061 of the adherent bone ring 308 , in other words, the first wave-shaped ring 3061 of the adherent bone ring 308 is closer to the branch bracket 3 than the second wave-shaped ring 3062 of the adherent bone ring 308 the far end. A branch rod 3064 of the second wave-shaped ring 3062 of the adherent bone ring 308 is provided with a fixed position, and the fixed position on the second wave-shaped ring 3062 of the adherent bone ring 308 makes the flexible bone ring 307 close to the distal end of the branch bracket 3 Fixing on the second wave-shaped ring 3062 of the adherent bone ring 308 is beneficial to further improve the structural stability of the flexible bone ring 307 in the axial direction of the branch bracket 3 .

The branch bracket 3 is inserted into the built-in bracket 2 through at least part of the support section 302, and the end of the support section 302 away from the wall-adhering section 304 extends out of the distal end of the built-in bracket 2, so that the branch bracket 3 can be more stably inserted into the inner bracket. Embedded in the stent 2, it is beneficial to improve the problem of displacement of the implanted stent, thereby helping to avoid at least partial occlusion of the branch stent 3 due to displacement, and improve the long-term patency of the branch artery; at the same time, the diameter of the support section 302 The radial dimension larger than that of the embedded stent 2 can better expand the embedded stent 2, which is beneficial to avoid affecting the blood flow of the branch arteries. At least part of the flexible section 303 and the wall-attached section 304 of the branch stent 3 are used to be implanted into the branch artery. If the angle between the branch artery (such as the left clavicle artery) and the target blood vessel (such as the aortic arch 5 ) is an acute angle (the acute angle is the angle between the branch artery and the target blood vessel that is far away from the end of the heart), the flexible section 303 It has better flexibility, can adapt to the anatomical structure of the curved blood vessel, and is beneficial to reduce the risk of occlusion of the branch stent 3 due to the acute angle formed between the branch artery and the target blood vessel. The wall-adhering section 304 can reduce the stimulation to the blood vessel wall, and has good adhesion. Different designs are adopted for different regions along the axial direction of the branch stent 3 , so that the branch stent 3 can adapt to different requirements of different branch vessels for the structure of the branch stent 3 .

The tubular covering 10, the insert covering 21, and the branch covering 301 are all biocompatible fabrics, including but not limited to woven or knitted polyester such as polyethylene terephthalate, polyethylene terephthalate Glycol esters, polylactides, polyglycolides and their copolymers; fluorinated polymers such as polytetrafluoroethylene, expanded or electrospun polytetrafluoroethylene and polyvinylidene fluoride; polysiloxanes such as Polydimethylsiloxanes; Polyurethanes such as polyether polyurethanes, polyurethane ureas, polyether polyurethane ureas, polyurethanes containing carbonate linkages, wound nickel titanium and polyurethanes containing siloxane segments; silicones, ultra-high molecular weight Polyethylene, fluorinated ethylene propylene copolymer, or other suitable material. In this embodiment, the tubular coating 10 and the embedded coating 21 are made of PET material, and the branch coating 301 is made of e-PTFE material. Limit.

The support frame 30, the embedded frame 22 and the branch frame all adopt elastic materials, so that the support frame, the embedded frame 22 and the branch frame components can shrink or expand in the radial direction, that is, the support frame 30, the embedded frame 22 and the branch frame components With radial expansion ability, it can be compressed under the action of external force and self-expand or mechanically expand to return to the original shape and maintain the original shape after the external force is removed, so that it can adhere to the vessel wall through its radial support force after implantation . Elastomeric materials include, but are not limited to, nickel-titanium alloys, nickel-titanium superelastic alloys, cobalt-chromium-nickel-molybdenum alloys, copper-based shape memory alloys, iron-based shape memory alloys, medical stainless steel alloys, or various polymers such as polynorbornene, polyurethane , polylactic acid copolymer, etc.) and the like are made of one or more.

In a possible application scenario of a split-type single-embedded branch stent-graft, please refer to FIG. 10 , which is a schematic diagram of a scenario where a split-type single-embedded-branch covered stent is used for reconstruction of the aortic arch 5 . The blood vessel may be the aortic arch 5, release the split-type single embedded branch stent-graft in the aortic arch 5, and reconstruct at least one branch artery on the aortic arch 5 (such as branches of the brachiocephalic artery, left common carotid artery, and left clavicle artery 7) arteries) as an example. The split-type single embedded branch stent-graft is released in the aortic arch 5 , and the split-type single embedded branch covered stent can isolate the tumor cavity 8 formed by the aortic arch 5 or the dissection breach. The fenestration structure 4 on the split-type single embedded branch covered stent is aligned with the root opening of the branch artery, and one end of the branch stent 3 is released into the embedded stent 2 through the fenestration structure 4, and the other end of the branch stent 3 is released in the In order to reconstruct at least one branch artery on the aortic arch 5 (for example, branch arteries such as the brachiocephalic artery, the left common carotid artery, and the left clavicle artery). In this embodiment, reconstruction of the left clavicle artery is taken as an example.

The second embodiment of the present application provides a split-type single embedded branch covered stent, please refer to FIG. 11 , which is another exemplary structural diagram of the main body stent 1 . The difference between this embodiment and the split-type single embedded branch stent-graft provided in the first embodiment is that the structure of at least one first fully fixed skeleton 321 in this embodiment is different, and along the axial direction of the main body stent 1, The window structure 4 is located between at least one adherent frame 31 and at least one first full-fixed frame 321 , in other words, at least one first full-fixed frame 321 is located at the distal side of the fenestration structure 4 . In this embodiment, the second full fixing frame 322 , the first reinforcing frame 33 and the second reinforcing frame 323 can be omitted.

In this embodiment, two adjacent support rods 3001 forming troughs 3003 on at least one first fully fixed frame 321 enclose and form a reinforcing part 36. For the convenience of distinction, the two supporting rods 3001 forming a reinforcing part 36 are named respectively These are the first support rod 361 and the second support rod 362 , and the trough 3003 formed by connecting the distal end of the first support rod 361 with the distal end of the second support rod 362 is a reinforced trough 363 . The first support rod 361, the second support rod 362 and the reinforcement trough 363 form a semi-circular structure surrounding at least part of the window structure 4, which is conducive to improving the adhesion of the window structure 4 and better preventing internal leakage Effect.

Please refer to FIG. 12 in conjunction with FIG. 12 . FIG. 12 is a schematic diagram of an enlarged structure at point A in FIG. 11 . At least one first full fixation frame 321 forms a wall-adhering area on a side away from the proximal end of the main body bracket 1 , and forms an escape area on a side close to the proximal end of the main body bracket 1 . Specifically, along the circumferential direction of the main body stent 1, at least two troughs 3003 adjacent to both sides of the reinforcement trough 363 and the reinforcement trough 363 are farther away from the proximal end of the main body stent 1 than other troughs 3003 on the first full fixed frame 321 , at least two crests 3002 adjacent to both sides of the reinforced trough 363 are farther away from the proximal end of the main body bracket 1 than the other crests 3002 on the first fully fixed frame 321. The troughs 3003 are respectively named as the first adherent trough 364 and the second adherent trough 365 , and at least two peaks 3002 adjacent to both sides of the reinforced trough 363 are respectively named as the first avoiding peak 366 and the second avoiding peak 367 . Along the circumferential direction of the main body bracket 1, the first wall-adhering trough 364 and the second wall-attaching trough 365 are respectively located on both sides of the reinforcement trough 363, and the first avoidance peak 366 and the second avoidance peak 367 are respectively located at the reinforcement trough 363 on both sides. Between the proximal ends of the two support rods 3001 forming the first avoidance peak 366 and the two support rods 3001 forming the second avoidance peak 367 to the proximal ends of the support rods 3001 forming other peaks 3002 in the first fully fixed frame 321 The axial length between them is the axial length of the escaping area, and the length of the escaping area can be 2-4mm. The setting of the escaping area is beneficial to avoid the process of radial compression or self-expansion of the main body stent 1 and returning to the predetermined shape. Extruding the window structure 4 is beneficial for the window structure 4 to return to a predetermined shape more smoothly after self-expansion. The distal ends of the two support rods 3001 forming the first adherent trough 364, the two support rods 3001 forming the second adherent trough 365, and the two support rods 3001 forming the reinforcing trough 363 are formed in the first full fixed skeleton 321 The axial length between the distal ends of the support rods 3001 of the other troughs 3003 is the axial length of the wall-attached area, and the length of the wall-attached area can be 3-5mm. The effect of the adherence of the supporting framework 30 is beneficial to reduce the bird’s beak sign after the proximal end of the tubular membrane 10 is implanted into a curved target blood vessel, that is, it is beneficial to reduce the proximal end of the tubular membrane 10 implanted into a curved target blood vessel. Finally, the lesser curved side 6 at the proximal end of the main body stent 1 is more difficult to fit closely with the vessel wall, and a gap is likely to appear between the lesser curved side 6 at the proximal end of the main body stent 1 and the vessel wall, resulting in Type Ia endoleak.

All of the above are preferred embodiments of the application, and are not intended to limit the protection scope of the application. Therefore, all equivalent changes made according to the structure, shape, and principle of the application should be covered by the protection scope of the application. Inside.

Claims (21)

1. A split single embedded branch stent graft, comprising:

the main body support is of a tubular structure with two open ends, the main body support is enclosed into a communication cavity for communicating with a target blood vessel, and the main body support is provided with at least one windowing structure;

the embedded support is of a tubular structure with two open ends, and one end of the embedded support is fixed on the windowing structure in a sealing mode, so that the windowing structure is communicated with the communication cavity of the main body support through the embedded support; and

The branch support is of a tubular structure with two open ends, the branch support is enclosed into a connecting cavity for communicating with a branch artery, and the branch support is detachably inserted into the embedded support through the windowing structure so as to enable the connecting cavity of the branch support to be communicated with the connecting cavity;

the main body support comprises a tubular tectorial membrane and a plurality of supporting frameworks, the supporting frameworks are sequentially arranged and fixed along the axial direction of the tubular tectorial membrane, each supporting framework comprises a plurality of supporting rods which are sequentially connected with each other in an included angle, two adjacent included angles are respectively a wave crest and a wave trough along the circumferential direction of the main body support, and the wave crest is closer to the proximal end of the main body support than the wave trough; the supporting framework comprises at least one first full-fixed framework, two adjacent supporting rods forming the trough on the at least one first full-fixed framework are enclosed to form a reinforcing part, the trough formed by connecting the distal ends of the two supporting rods on the reinforcing part is a reinforcing trough, and the two supporting rods on the reinforcing part and the reinforcing trough form a semi-annular structure surrounding at least part of the windowing structure;

Along in the circumference direction of main part support, at least two of the trough of strengthening the trough both sides is first adherence trough and second adherence trough respectively, first adherence trough, second adherence trough with strengthen the trough compare other on the first full fixed skeleton the trough is more kept away from the proximal end of main part support is in order to form the adherence district.

2. The split type single-embedded branch stent-graft of claim 1, wherein the branch stent comprises a branch stent-graft and a branch skeleton assembly fixed to the branch stent-graft, the branch stent-graft comprises a first layer of film and a second layer of film along the radial direction of the branch stent, the first layer of film is positioned at the inner side of the connecting cavity of the branch stent, the second layer of film is positioned at the outer side of the branch stent, the branch skeleton assembly is fixed between the first layer of film and the second layer of film, the proximal end and the distal end of the branch stent-graft are respectively integrally formed with a turnover section, and the turnover section is fixed to the inner peripheral wall of the branch stent-graft; the axial length of the turnover section is 1-5mm.

3. The split type single embedded branch stent graft of claim 2, wherein the main body stent comprises a tubular stent graft, a bare stent and a plurality of supporting frameworks, the bare stent and the supporting frameworks are in annular structures, the bare stent is fixed at the proximal end of the tubular stent graft, the supporting frameworks are positioned at the distal end side of the bare stent, and the supporting frameworks are sequentially arranged and fixed along the axial direction of the tubular stent graft; the bare support and the support framework comprise a plurality of support rods which are sequentially connected with each other in an included angle manner, two adjacent included angles are respectively a peak and a trough along the circumferential direction of the main body support, and the peak is closer to the proximal end of the main body support than the trough; at least part of the peaks, the troughs and the support rods of the support framework are all attached to and fixed on the peripheral wall of the tubular coating, at least part of the peaks of the support framework are provided with gaps with the tubular coating and can be separated from the tubular coating to form a free zone, and the axial length of the free zone is at least 2.5-4mm.

4. The split type single embedded branched stent graft of claim 3, wherein a plurality of said supporting frameworks comprise an adherent framework, a bundle diameter framework, an auxiliary framework and a distal framework which are sequentially arranged from the proximal end to the distal end of said tubular stent graft, said adherent framework and said bundle diameter framework are both positioned on the proximal side of said fenestration, and said auxiliary framework and said distal framework are both positioned on the distal side of said fenestration; the wave trough of the bare stent is fixed on the tubular tectorial membrane, and the wave crest of the bare stent and the supporting rod of the bare stent extend out of the proximal end of the tubular tectorial membrane at least partially; the axial lengths of the supporting rods on the adherence framework are the same; the plurality of beam diameter frameworks are arranged, and the axial lengths of all the support rods on at least one beam diameter framework are the same; the axial length of each supporting rod on the distal framework is the same;

the auxiliary frameworks are provided with at least two, the wave troughs of two adjacent auxiliary frameworks are opposite in the axial direction, and the wave crests of two adjacent auxiliary frameworks are opposite in the axial direction; along the circumferential direction of the main body support, two adjacent wave crests on the auxiliary skeleton comprise high waves and low waves, and the high waves are closer to the proximal end of the main body support than the low waves; in the peaks on the auxiliary skeleton, the high waves and the low waves are alternately arranged along the circumferential direction of the main body support.

5. The split single-embedded branched stent graft of claim 4, wherein said troughs of said bare stent are secured with a plurality of seaming loops by stitching to secure said troughs of said bare stent to said tubular stent, said strut is secured with at least one seaming loop by stitching to secure said strut of said bare stent to said tubular stent, and said seaming loops on said strut of said bare stent are immediately adjacent to said seaming loops on said troughs of said bare stent; the trough and the support rod of the bare stent are fixed on the axial length of the tubular tectorial membrane through the suture ring to form an anchoring zone, the axial length of the anchoring zone is at least 3-5mm, and the axial length of the anchoring zone is the superposition length of the bare stent and the wall-attached framework in the axial direction.

6. The split type single embedded branched stent graft of claim 4, wherein said wall-attached framework, said beam-diameter framework and said peaks, said troughs and said support bars of said distal framework are all affixed to the peripheral wall of said tubular stent graft; the trough, the support rod and the low wave of the auxiliary framework are all attached and fixed to the peripheral wall of the tubular coating, and a gap is reserved between the high wave of the auxiliary framework and the tubular coating and can be separated from the tubular coating so as to form a free zone.

7. The split type single embedded branched stent graft of any one of claims 4-6, wherein at least one of said wall-mounted frameworks is provided, at least one of said wall-mounted frameworks is positioned on a distal side of said bare stent, and the waveform profile of at least one of said wall-mounted frameworks is consistent with the waveform profile of said bare stent, such that said peaks of said wall-mounted frameworks can be positioned in an area between two adjacent support struts on said bare stent.

8. The split single-embedded branched stent graft of claim 7, wherein at least one of said first fully-fixed struts is distal to at least one of said wall-engaging struts; the axial length of each supporting rod on at least one first full-fixed framework is the same, and the wavelength of at least one first full-fixed framework is smaller than that of other supporting frameworks.

9. The split single-embedded branched stent graft of claim 8, wherein said bundle diameter scaffold further comprises at least a second fully secured scaffold, at least one of said second fully secured scaffold being distal to at least one of said first fully secured scaffold; along the circumferential direction of the main body support, two adjacent wave crests on at least one second full-fixed framework comprise high waves and low waves, and the high waves are closer to the proximal end of the main body support than the low waves; and in the wave crest on at least one second full-fixed framework, the high waves and the low waves are alternately arranged along the circumferential direction of the main body support.

10. The split single-embedded branched stent graft of claim 9, wherein a plurality of said struts further comprise at least a first reinforcement matrix, at least one of said first reinforcement matrix being located on a distal side of said fenestration; the beam diameter framework further comprises at least one second reinforcing framework, at least one second reinforcing framework is positioned at the far end side of at least one second full-fixed framework, the first reinforcing framework and the second reinforcing framework are adjacently arranged in the axial direction, and the first reinforcing framework and the second reinforcing framework are respectively positioned at two sides of the windowing structure in the axial direction; the axial lengths of the supporting rods on at least one first reinforcing framework are the same, the axial lengths of the supporting rods on at least one second reinforcing framework are the same, the wave crests, the wave troughs and the supporting rods on at least one first reinforcing framework are all adhered and fixed on the peripheral wall of the tubular coating, and the wave troughs on the first reinforcing framework are opposite to the wave crests on the second reinforcing framework in the axial direction.

11. The split single-embedded branched stent graft of claim 1, wherein the axial length between the distal ends of the two struts forming the first wall-attached trough, the two struts forming the second wall-attached trough, and the two struts forming the reinforcing trough to the distal ends of the struts forming the other trough in the first fully-fixed frame is the axial length of the wall-attached region, and the axial length of the wall-attached region is 3-5mm.

12. The split type single embedded branch stent graft according to claim 1, wherein in the circumferential direction of the main body stent, at least two peaks at two sides of the reinforcing trough are a first avoidance peak and a second avoidance peak, the first avoidance peak and the second avoidance peak are further away from the proximal end of the main body stent than other peaks on the first fully fixed skeleton to form a avoidance zone, and the axial length between the proximal ends of the two support rods forming the first avoidance peak and the proximal ends of the two support rods forming the second avoidance peak to the proximal ends of the support rods forming other peaks in the first fully fixed skeleton is the axial length of the avoidance zone, and the axial length of the avoidance zone is 2-4mm.

13. The split single-embedded branched stent graft of claim 6, wherein at least two distal end frames are provided, at least two distal end frames are sequentially arranged along the axial direction of the tubular stent graft, the distal end of the tubular stent graft is provided with at least one development mark, the development mark is positioned at least one of the proximal end and the proximal end side of at least two distal end frames near the distal end port of the tubular stent graft, the axial length of the development mark and the distal end edge of the tubular stent graft is at least 30-50mm, and the development mark is used for indicating the position of another external stent graft in the communication cavity of the main body stent.

14. The split single embedded branched stent graft of claim 4, further comprising a plurality of sets of flexible beam diameter members on the proximal side of the fenestration, said flexible beam diameter members for radially compressing a portion of said main body stent on the proximal side of said fenestration; the wall-attaching framework and the wave crests, the wave troughs and the supporting rods of the beam-diameter framework are all attached and fixed to the peripheral wall of the tubular tectorial membrane, at least one wave trough of the bare stent is provided with a flexible beam-diameter member, at least one wave trough of the wall-attaching framework is provided with a flexible beam-diameter member, at least one wave trough and at least one wave crest adjacent to each beam-diameter framework are all provided with flexible beam-diameter members, a plurality of flexible beam-diameter members are approximately arranged and extend along the axial direction of the main body stent, and the beam-diameter members are used for radially compressing local parts located at the proximal end side of the windowing structure.

15. The split single-embedded branched stent graft of claim 14, wherein said flexible beam member is of a loop configuration, any at least two points on the loop of said beam member being secured to said main body stent to form two securing points, thereby forming said flexible beam member into at least two flexible loops; alternatively, the flexible beam diameter member includes at least two flexible rings, one end of the flexible rings in the length direction is fixed to at least one of the tubular covering film and the supporting skeleton to form a fixing site;

Along the circumference of main part support, two the flexible ring is kept away from the one end of fixed site can coincide each other in order to form the wire loop that supplies the footpath seal wire to wear to establish, the length direction of flexible ring can be followed the circumference of main part support is arranged, and at least two the length direction of flexible ring can encircle the circumference of main part support is in order to make the main part support can radial compression.

16. The split single-embedded branched stent graft of claim 1, wherein the embedded stent graft comprises an embedded stent graft and a plurality of embedded frameworks, the embedded frameworks are sequentially arranged along the axial direction of the embedded stent graft, the far end opening of the embedded stent graft is an inclined opening, the embedded frameworks are in an open-loop structure, and the open-loop opening of the embedded frameworks is positioned on one side of the embedded stent graft close to the inner wall of the main body stent graft.

17. The split single-embedded branch stent graft of claim 3, wherein said branch stent graft comprises a support section, a flexible section and an attachment section connected in sequence from a proximal end to a distal end, said branch stent graft assembly comprising a support bone ring, a flexible bone ring and an attachment bone ring arranged in sequence along an axial direction of said branch stent graft, said support bone ring being positioned at said support section, said flexible bone ring extending in sequence from at least a portion of said support section, said flexible section, at least a portion of said attachment section, said attachment bone ring being positioned at said attachment section;

The flexible support comprises a flexible section, a support section and an adherence section, wherein the support section and the adherence section are of an equal-diameter structure, the flexible section adopts a taper design, the radial size of the proximal end of the flexible section is larger than the radial size of the distal end of the flexible section, the proximal end of the flexible section is connected with the support section, the distal end of the flexible section is connected with the adherence section, the radial size of the support section is larger than the radial size of the adherence section, and the radial size of the support section is larger than the radial size of the embedded bracket.

18. The split type single-embedded branch stent graft of claim 17, wherein said supporting bone ring comprises a plurality of first wavy rings, at least one second wavy ring and a connecting bone, said plurality of first wavy rings and said at least one second wavy ring are sequentially arranged along the axial direction of said branch stent, said second wavy rings are positioned at the distal end side of said first wavy rings, said first wavy rings and said second wavy rings each comprise a plurality of branching bars which are sequentially connected in an included angle, and in the circumferential direction of said branch stent, adjacent two included angles are a peak and a trough, respectively, said peak being closer to the proximal end of said branch stent than said trough; each first wavy ring is provided with at least one fixing position which is fixed with the connecting bone, so that the connecting bone axially connects a plurality of first wavy rings, and the fixing position is positioned on the branch rod of each first wavy ring; the structure of the wall-attached bone ring is the same as that of the supporting bone ring.

19. The split single-embedded branched stent graft of claim 18, wherein said anchor is a sleeve that secures said connecting bone to said split struts corresponding to each of said first undulating rings; alternatively, at least part of the fixation sites are formed by spirally winding the branch bars of each of the first wavy rings on the connective bone to the connective bone.

20. The split single-embedded branched stent graft of any one of claims 18-19, wherein said connecting bone extends along adjacent said support struts connecting two of said first undulating rings in the axial direction of said branched stent such that said connecting bone is of an oblique linear shape extending from the proximal end to the distal end of said support segments.

21. The split type single embedded branch stent graft of claim 20, wherein said flexible bone ring comprises a plurality of wave units, said flexible bone ring is a tubular structure formed by a plurality of wave units connected end to end and continuously and spirally arranged along the periphery of said first layer of membrane, said wave units comprise a plurality of unit rods connected in sequence with included angles, two adjacent included angles are respectively a peak and a trough along the periphery of said branch stent, said peak is closer to the proximal end of said branch stent than said trough; the fixing position is arranged on one of the branch rods on the second wavy ring of the supporting bone ring, and the fixing position on the second wavy ring of the supporting bone ring is used for fixing one end, close to the proximal end of the branch bracket, of the flexible bone ring on the second wavy ring of the supporting bone ring; one end of the flexible bone ring, which is close to the distal end of the branch bracket, is fixed on the wall-attached bone ring.

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