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CN115736987A - Rapid imaging method for breast positioning of hemispherical ultrasonic tomography system - Google Patents

Rapid imaging method for breast positioning of hemispherical ultrasonic tomography system Download PDF

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CN115736987A
CN115736987A CN202211458517.6A CN202211458517A CN115736987A CN 115736987 A CN115736987 A CN 115736987A CN 202211458517 A CN202211458517 A CN 202211458517A CN 115736987 A CN115736987 A CN 115736987A
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breast
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imaging method
tomography system
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CN115736987B (en
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雷晓旭
黄跃龙
韩春林
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Zhejiang Hengjiu Medical Devices Co ltd
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Abstract

The invention belongs to the field of ultrasonic tomography, and particularly relates to a quick imaging method for breast positioning of a hemispherical ultrasonic tomography system, which comprises the following steps: acquiring empty water data; breast data acquisition; analyzing the collected data; preprocessing the analyzed data; calculating an attenuation coefficient; carrying out image reconstruction; processing the reconstructed image, storing the processed image in a specified memory position, and periodically reading the processed image through a GUI (graphical user interface) terminal; and displaying the breast position images of the coronal plane and the sagittal plane through a GUI end, and judging whether the breast position of the patient is in the optimal area. The invention can image a pair of coronal planes and a pair of sagittal plane acoustic attenuation rate images in real time, can judge whether the breast in XY direction is in the optimal imaging area through the coronal plane, and can judge whether the patient in Z direction is deep enough through the sagittal plane.

Description

一种半球形超声断层成像系统乳房定位用快速成像方法A fast imaging method for breast positioning in a hemispherical ultrasonic tomography system

技术领域technical field

本发明属于超声断层成像领域,具体涉及一种半球形超声断层成像系统乳房定位用快速成像方法。The invention belongs to the field of ultrasonic tomography, in particular to a fast imaging method for breast positioning in a hemispherical ultrasonic tomography system.

背景技术Background technique

超声断层成像的成像空间为三维,但最佳成像区域一般都比成像孔径尺寸小。当病人俯卧在设备上时,肉眼不能很好判断乳房是否在最佳成像区域内。现有光学摄像头方式不能准确判断病人乳房位置且成像效果差异大。The imaging space of ultrasonic tomography is three-dimensional, but the optimal imaging area is generally smaller than the imaging aperture size. When the patient lies prone on the device, the naked eye cannot judge whether the breast is in the optimal imaging area. The existing optical camera method cannot accurately judge the position of the patient's breast and the imaging effect varies greatly.

公开号为CN113598825A的中国专利公开了一种用于超声成像系统的乳房定位成像方法及其应用,该方案包括以下步骤:设定超声换能器阵元的序列,每个所述超声换能器阵元按照所述序列进行发射和采集超声信号操作;依据采集到的所述超声信号计算获得乳房一层冠状面的轮廓;对所述轮廓进行空间坐标转换,得到所述轮廓在超声成像系统的横切面中的空间分布,本发明具有定位精度高,成像效果好的优点。The Chinese patent with the publication number CN113598825A discloses a breast positioning imaging method for an ultrasonic imaging system and its application. The solution includes the following steps: setting the sequence of ultrasonic transducer array elements, each of the ultrasonic transducers The array element transmits and collects ultrasonic signals according to the sequence; calculates and obtains the contour of the coronal surface of the first layer of the breast according to the collected ultrasonic signals; performs spatial coordinate conversion on the contour, and obtains the contour in the ultrasonic imaging system. Spatial distribution in the cross-section, the present invention has the advantages of high positioning accuracy and good imaging effect.

然而,上述乳房定位成像方法依然存在以下缺点:However, the above-mentioned breast localization imaging method still has the following disadvantages:

对比度差,噪声明显,不易有效辨别出乳房的位置,且只有一个切面的展示(X,Y方向),没有深度方向信息。The contrast is poor, the noise is obvious, it is difficult to effectively identify the position of the breast, and there is only one section display (X, Y direction), and there is no depth direction information.

发明内容Contents of the invention

为了弥补现有技术的不足,本发明提供一种半球形超声断层成像系统乳房定位用快速成像方法技术方案。In order to make up for the deficiencies in the prior art, the present invention provides a technical proposal of a rapid imaging method for breast positioning in a hemispherical ultrasonic tomographic imaging system.

一种半球形超声断层成像系统乳房定位用快速成像方法,包括:A fast imaging method for breast positioning of a hemispherical ultrasonic tomography system, comprising:

步骤1,空水数据采集;Step 1, empty water data collection;

步骤2,乳房数据采集;Step 2, breast data collection;

步骤3,对采集的数据进行解析;Step 3, analyzing the collected data;

步骤4,对解析后的数据进行预处理;Step 4, preprocessing the parsed data;

步骤5,计算衰减系数;Step 5, calculating the attenuation coefficient;

步骤6,进行图像重建;Step 6, carry out image reconstruction;

步骤7,对重建后的图像进行处理,处理后的图像存放在指定内存位置,通过GUI端周期性读取。Step 7: Process the reconstructed image, store the processed image in a designated memory location, and periodically read it through the GUI terminal.

进一步地,所述步骤1和步骤2中,每次采集时,冠状面和矢状面的数据同时采集。Further, in the step 1 and step 2, the data of the coronal plane and the sagittal plane are collected at the same time during each collection.

进一步地,所述步骤3包括:Further, said step 3 includes:

将发射TAS序号,发射阵元序号,接收TAS序号,接收阵元序号及一段AScan对应起来,保存在内存中。Correspond the transmitting TAS serial number, transmitting array element serial number, receiving TAS serial number, receiving array element serial number and an AScan, and store them in the memory.

进一步地,所述步骤3包括:将矢状面数据和冠状面数据区分开来,分别用于矢状面和冠状面图像的重建。Further, the step 3 includes: distinguishing the sagittal plane data and the coronal plane data, and using them for reconstruction of sagittal plane and coronal plane images respectively.

进一步地,所述步骤4包括:Further, said step 4 includes:

步骤4.1,按照下面公式计算每一段AScan信号的能量:Step 4.1, calculate the energy of each AScan signal according to the following formula:

Figure BDA0003954056860000021
Figure BDA0003954056860000021

式中,L是发射信号的特征长度,t0是直达波到达时间;In the formula, L is the characteristic length of the transmitted signal, and t0 is the arrival time of the direct wave;

步骤4.2,LOR排序,包括:将所有发射阵元和接收阵元对连线,求该Line在原来直角坐标系下进行极坐标变换的结果,将信号排列为(R,theta)矩阵,R为路径到中心点的距离,theta为路径与坐标轴夹角,其中,矢状面和冠状面的数据分开做LOR排序。Step 4.2, LOR sorting, including: connecting all transmitting array elements and receiving array element pairs, finding the result of polar coordinate transformation of the Line in the original Cartesian coordinate system, and arranging the signals into (R, theta) matrix, R is The distance from the path to the center point, theta is the angle between the path and the coordinate axis, and the data of the sagittal plane and the coronal plane are separately sorted by LOR.

进一步地,所述步骤5包括:Further, said step 5 includes:

根据步骤4中算出的能量I,将排序好的空水和乳房数据按照下面公式计算:According to the energy I calculated in step 4, the sorted empty water and breast data are calculated according to the following formula:

Atten=log(I空水/I物体)Atten=log(I empty water /I object )

其中,Atten为每个发射接收对的衰减系数。Wherein, Atten is the attenuation coefficient of each transmitting and receiving pair.

进一步地,所述步骤6包括:Further, said step 6 includes:

将处理后的Atten按照下面的公式进行重建:Reconstruct the processed Atten according to the following formula:

Figure BDA0003954056860000031
Figure BDA0003954056860000031

Figure BDA0003954056860000032
Figure BDA0003954056860000032

Figure BDA0003954056860000033
Figure BDA0003954056860000033

其中,f是图像,k是迭代次数,n是像素序号,wmn是第m个衰减和第n个像素的相交距离,pm是第m个衰减值,

Figure BDA0003954056860000034
是第m个加权投影的衰减值,Wm+是第m个衰减对应的归一化因子,λk是第k次迭代的系数,
Figure BDA0003954056860000035
是整个成像系统的采样点,wm’n是像素n和所有衰减相交距离之和,m'用来计算像素n和所有衰减相交距离的和,是一个常数的加权,可以提出去。Among them, f is the image, k is the number of iterations, n is the pixel number, w mn is the intersection distance between the mth attenuation and the nth pixel, p m is the mth attenuation value,
Figure BDA0003954056860000034
is the attenuation value of the mth weighted projection, W m+ is the normalization factor corresponding to the mth attenuation, λ k is the coefficient of the kth iteration,
Figure BDA0003954056860000035
is the sampling point of the entire imaging system, w m'n is the sum of pixel n and all attenuation intersection distances, m' is used to calculate the sum of pixel n and all attenuation intersection distances, and is a constant weight, which can be proposed.

进一步地,所述步骤7包括:Further, said step 7 includes:

步骤7.1,将重建的图像值映射到0~255区间;Step 7.1, mapping the reconstructed image value to the interval of 0-255;

步骤7.2,根据理论最佳成像区域,对矢状面和冠状面重建的图像分别加入一个矩形框的Mask,保留Mask内的图像,Mask以外的图像置为0,处理后的图像存放在指定内存位置,通过GUI端周期性读取。Step 7.2, according to the theoretical optimal imaging area, add a rectangular mask to the reconstructed images of the sagittal plane and the coronal plane respectively, keep the images in the Mask, set the images other than the Mask to 0, and store the processed images in the designated memory The position is periodically read through the GUI.

进一步地,还包括步骤8包括:GUI端通过两个窗口分别展示冠状面和矢状面的乳房位置图像,用以判断病人乳房位置是否在最佳区域。Further, step 8 also includes: the GUI terminal displays the breast position images of the coronal plane and the sagittal plane respectively through two windows, so as to judge whether the patient's breast position is in the optimal area.

与现有技术相比,本发明的有益效果是:Compared with prior art, the beneficial effect of the present invention is:

本发明可以实时将一副冠状面和一副矢状面的声衰减率图成像出来,通过冠状面可以判断XY方向上乳房是否在最佳成像区域,通过矢状面可以判断Z方向上病人俯卧的是否足够深,本发明集成在GUI操作界面上,图像实时在GUI中显示,方便操作以及判断病人乳房位置是否在最佳区域。The present invention can image a pair of coronal plane and a pair of sagittal plane sound attenuation rate maps in real time, judge whether the breast is in the best imaging area in the XY direction through the coronal plane, and judge whether the patient is prone in the Z direction through the sagittal plane Whether it is deep enough, the present invention is integrated on the GUI operation interface, and the image is displayed in the GUI in real time, which is convenient for operation and judging whether the position of the patient's breast is in the optimal area.

附图说明Description of drawings

图1为本发明流程图。Fig. 1 is the flow chart of the present invention.

具体实施方式Detailed ways

下面结合附图对本发明作进一步说明。The present invention will be further described below in conjunction with accompanying drawing.

本发明所采用的半球支架参考专利CN113598825A,本发明的超声换能器阵列以及超声换能器阵元按照专利CN113598825A中的方法设定序号。The hemispherical support used in the present invention refers to the patent CN113598825A, and the serial numbers of the ultrasonic transducer array and the ultrasonic transducer array elements of the present invention are set according to the method in the patent CN113598825A.

请参阅图1,一种半球形超声断层成像系统乳房定位用快速成像方法,包括以下步骤:Please refer to Fig. 1, a kind of hemispherical ultrasonic tomography system breast localization fast imaging method, comprises the following steps:

步骤1,空水数据采集Step 1, air and water data collection

空水数据采集就是只有水没有物体时进行数据采集,作用是为本发明提供一个基准。Empty water data collection is exactly to carry out data collection when only water has no object, and effect is to provide a benchmark for the present invention.

发射接收换能器的选择遵循几何空间位置的原则为:选择被成切面和半球形换能器相交处的TAS。每次采集时,冠状面和矢状面的数据同时采集。The selection of transmitting and receiving transducers follows the principle of geometric space position: select the TAS at the intersection of the tangent plane and the hemispherical transducer. Data in the coronal and sagittal planes are collected simultaneously for each acquisition.

步骤2,乳房数据采集Step 2, breast data collection

对乳房进行数据采集,采用的超声换能器和采集方式同上。For data collection of the breast, the ultrasonic transducer and collection method used are the same as above.

步骤3,数据解析Step 3, data analysis

主要为将发射TAS序号,发射阵元序号,接收TAS序号,接收阵元序号及一段AScan(4000个点)给对应起来,保存内存中。同时本步骤将矢状面和冠状面区分开来,分别用于矢状面和冠状面图像的重建。The main purpose is to match the transmitting TAS serial number, transmitting array element serial number, receiving TAS serial number, receiving array element serial number and a section of AScan (4000 points), and store them in the memory. At the same time, this step distinguishes the sagittal plane and the coronal plane, which are used for reconstruction of the sagittal plane and coronal plane images respectively.

步骤4,数据预处理Step 4, data preprocessing

步骤4.1,计算每一段AScan信号的能量,按照下面公式进行积分:Step 4.1, calculate the energy of each AScan signal, and integrate according to the following formula:

Figure BDA0003954056860000051
Figure BDA0003954056860000051

其中,L是发射信号的特征长度,t0是直达波到达时间。Among them, L is the characteristic length of the transmitted signal, and t0 is the arrival time of the direct wave.

步骤4.2,LOR(Line of Response)重新排序。具体做法为按照信号的几何位置,将其重新排序。将所有发射阵元和接收阵元对连线,求该Line在原来直接坐标系下进行极坐标变换,将信号排列为(R,theta)矩阵。R为路径到中心点的距离,theta为路径与坐标轴夹角。在这一步中需要将矢状面和冠状面的数据分开做LOR的排序。Step 4.2, LOR (Line of Response) reordering. This is done by reordering the signals according to their geometrical position. Connect all transmitting array elements and receiving array element pairs, find the polar coordinate transformation of the Line in the original direct coordinate system, and arrange the signals into an (R, theta) matrix. R is the distance from the path to the center point, and theta is the angle between the path and the coordinate axis. In this step, the data of the sagittal plane and the coronal plane need to be sorted separately for LOR.

步骤5,计算衰减系数Step 5, calculate the attenuation coefficient

根据在步骤4中算出的能量I,将排序好的空水和乳房数据按照下面公式计算:According to the energy I calculated in step 4, the sorted empty water and breast data are calculated according to the following formula:

Atten=log(I/I物体)Atten=log(I water /I object )

Atten即为每个发射接收对的衰减系数。Atten is the attenuation coefficient of each transmitting and receiving pair.

步骤6,图像重建Step 6, image reconstruction

将处理后的Atten按照下面的公式进行重建。Reconstruct the processed Atten according to the following formula.

Figure BDA0003954056860000052
Figure BDA0003954056860000052

Figure BDA0003954056860000053
Figure BDA0003954056860000053

Figure BDA0003954056860000061
Figure BDA0003954056860000061

其中,f是图像,k是迭代次数,n是像素序号,wmn是第m个衰减和第n个像素的相交距离,pm是第m个衰减值,

Figure BDA0003954056860000063
是第m个加权投影的衰减值,Wm+是第m个衰减对应的归一化因子,λk是第k次迭代的系数,
Figure BDA0003954056860000064
是整个成像系统的采样点,m'用来计算像素n和所有衰减相交距离的和,是一个常数的加权,可以提出去。Among them, f is the image, k is the number of iterations, n is the pixel number, w mn is the intersection distance between the mth attenuation and the nth pixel, p m is the mth attenuation value,
Figure BDA0003954056860000063
is the attenuation value of the mth weighted projection, W m+ is the normalization factor corresponding to the mth attenuation, λ k is the coefficient of the kth iteration,
Figure BDA0003954056860000064
is the sampling point of the entire imaging system, m' is used to calculate the sum of pixel n and all attenuation intersection distances, which is a constant weighting and can be proposed.

步骤7,图像处理Step 7, image processing

步骤7.1,将重建的图像值映射到0~255区间。Step 7.1, map the reconstructed image value to the interval of 0-255.

步骤7.2,根据理论最佳成像区域,对矢状面和冠状面重建的图像分别加入一个矩形框的Mask,Mask是一个最佳区域内为1外部为0的二维矩阵,在Mask内的图像保留,以外的置为0。处理后的图像会存放在指定内存位置,GUI端周期性读取。Step 7.2, according to the theoretical optimal imaging area, add a rectangular mask to the reconstructed images of the sagittal plane and the coronal plane, respectively. Mask is a two-dimensional matrix with 1 in the optimal area and 0 outside, and the image in the Mask Reserved, others are set to 0. The processed image will be stored in the specified memory location, and the GUI terminal will periodically read it.

步骤8,图像GUI展示Step 8, image GUI display

GUI端(图形用户界面)有两个窗口分别展示冠状面和矢状面的乳房位置图像,用以判断病人乳房位置是否在最佳区域。若乳房未在最佳成像区域,则指导病人移动,调整乳房位置直到乳房在最佳区域。There are two windows on the GUI side (graphical user interface) to display the breast position images of the coronal plane and the sagittal plane respectively, to judge whether the patient's breast position is in the optimal area. If the breast is not in the optimal imaging area, instruct the patient to move and adjust the breast position until the breast is in the optimal area.

最后应说明的是:以上各实施例仅用以说明本发明的技术方案,而非对其限制;尽管参照前述各实施例对本发明进行了详细的说明,本领域的普通技术人员应当理解:其依然可以对前述各实施例所记载的技术方案进行修改,或者对其中部分或者全部技术特征进行等同替换;而这些修改或者替换,并不使相应技术方案的本质脱离本发明各实施例技术方案的范围。Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present invention, rather than limiting them; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: It is still possible to modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the technical solutions of the various embodiments of the present invention. scope.

Claims (9)

1. A fast imaging method for locating a breast of a hemispherical ultrasonic tomography system is characterized by comprising the following steps:
step 1, acquiring empty water data;
step 2, breast data acquisition;
step 3, analyzing the acquired data;
step 4, preprocessing the analyzed data;
step 5, calculating an attenuation coefficient;
step 6, reconstructing an image;
and 7, processing the reconstructed image, and storing the processed image in a specified memory location.
2. The fast imaging method for locating the breast in the hemispherical ultrasonic tomography system as claimed in claim 1, wherein in the step 1 and the step 2, the data of the coronal plane and the data of the sagittal plane are acquired simultaneously at each acquisition.
3. The fast imaging method for breast localization in hemispherical ultrasound tomography system according to claim 1, wherein the step 3 comprises:
and the transmitting TAS serial number, the transmitting array element serial number, the receiving TAS serial number, the receiving array element serial number and a segment of AScan are corresponding and stored in the memory.
4. The fast imaging method for breast localization in hemispherical ultrasound tomography system according to claim 1, wherein the step 3 comprises: the sagittal plane data and the coronal plane data are distinguished and are respectively used for the reconstruction of sagittal plane images and coronal plane images.
5. The fast imaging method for breast localization of hemispherical ultrasonic tomography system as claimed in claim 1, wherein the step 4 comprises:
step 4.1, calculating the energy of each segment of the AScan signal according to the following formula:
Figure FDA0003954056850000021
wherein, L is the characteristic length of the transmitted signal, and t0 is the arrival time of the direct wave;
step 4.2, LOR sequencing, comprising: connecting all transmitting array elements and receiving array elements in a Line, solving the polar coordinate transformation result of the Line in the original rectangular coordinate system, arranging signals into (R, theta) matrixes, wherein R is the distance from a path to a central point, theta is the included angle between the path and coordinate axes, and the data of the sagittal plane and the coronal plane are separately subjected to LOR sequencing.
6. The fast imaging method for locating the breast of the hemispherical ultrasonic tomography system as claimed in claim 5, wherein the step 5 comprises:
and 4, calculating the sorted empty water and breast data according to the energy I calculated in the step 4 according to the following formula:
Atten=log(I empty water /I Object )
Wherein the Atten is the attenuation coefficient of each transmit-receive pair.
7. The fast imaging method for breast localization in hemispherical ultrasound tomography system according to claim 6, wherein the step 6 comprises:
the processed Atten is reconstructed according to the following formula:
Figure FDA0003954056850000022
Figure FDA0003954056850000023
Figure FDA0003954056850000024
where f is the image, k is the number of iterations, n is the pixel number, w mm Is the intersection distance, p, of the mth attenuation and the nth pixel m Is the m-th attenuation value of the signal,
Figure FDA0003954056850000025
is the attenuation value of the mth weighted projection, W m+ Is the normalization factor, λ, corresponding to the mth attenuation k Is the coefficient of the k-th iteration,
Figure FDA0003954056850000026
is the sampling point, w, of the entire imaging system m’n Is the sum of pixel n and all attenuation crossover distances, and m' is used to calculate the sum of pixel n and all attenuation crossover distances, which is a constant weight.
8. The fast imaging method for breast localization of hemispherical ultrasonic tomography system as claimed in claim 1, wherein the step 7 comprises:
step 7.1, mapping the reconstructed image value to an interval of 0-255;
and 7.2, respectively adding a Mask with a rectangular frame to the reconstructed images of the sagittal plane and the coronal plane according to the theoretical optimal imaging area, keeping the images in the Mask, setting the images except the Mask as 0, storing the processed images in a specified memory position, and periodically reading through a GUI (graphical user interface) terminal.
9. The fast imaging method for breast localization of hemispherical ultrasonic tomography system as claimed in claim 1, further comprising the step 8 of: the GUI end respectively displays the breast position images of the coronal plane and the sagittal plane through two windows so as to judge whether the breast position of the patient is in the optimal area.
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