CN115702849A - Dressing with pH indicating function and preparation method thereof - Google Patents
Dressing with pH indicating function and preparation method thereof Download PDFInfo
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- CN115702849A CN115702849A CN202110910642.5A CN202110910642A CN115702849A CN 115702849 A CN115702849 A CN 115702849A CN 202110910642 A CN202110910642 A CN 202110910642A CN 115702849 A CN115702849 A CN 115702849A
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- layer
- dressing
- indicating function
- cotton layer
- adhesive
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- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 239000010410 layer Substances 0.000 claims abstract description 69
- 229920000742 Cotton Polymers 0.000 claims abstract description 63
- 238000010521 absorption reaction Methods 0.000 claims abstract description 29
- BELBBZDIHDAJOR-UHFFFAOYSA-N Phenolsulfonephthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2S(=O)(=O)O1 BELBBZDIHDAJOR-UHFFFAOYSA-N 0.000 claims abstract description 23
- 229960003531 phenolsulfonphthalein Drugs 0.000 claims abstract description 20
- 239000007793 ph indicator Substances 0.000 claims abstract description 14
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims abstract description 11
- 239000011734 sodium Substances 0.000 claims abstract description 11
- 229910052708 sodium Inorganic materials 0.000 claims abstract description 11
- 239000011241 protective layer Substances 0.000 claims description 28
- 239000012790 adhesive layer Substances 0.000 claims description 24
- 239000007788 liquid Substances 0.000 claims description 14
- 239000000243 solution Substances 0.000 claims description 12
- 239000011358 absorbing material Substances 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 7
- 239000000853 adhesive Substances 0.000 claims description 6
- 230000001070 adhesive effect Effects 0.000 claims description 6
- 238000005520 cutting process Methods 0.000 claims description 6
- 239000011259 mixed solution Substances 0.000 claims description 4
- 239000004745 nonwoven fabric Substances 0.000 claims description 4
- 229920006264 polyurethane film Polymers 0.000 claims description 4
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 3
- 239000006261 foam material Substances 0.000 claims description 3
- 230000001954 sterilising effect Effects 0.000 claims description 3
- 230000002745 absorbent Effects 0.000 claims 1
- 239000002250 absorbent Substances 0.000 claims 1
- 229920001296 polysiloxane Polymers 0.000 claims 1
- 238000002791 soaking Methods 0.000 claims 1
- 206010052428 Wound Diseases 0.000 abstract description 26
- 208000027418 Wounds and injury Diseases 0.000 abstract description 26
- 208000015181 infectious disease Diseases 0.000 abstract description 7
- 206010048038 Wound infection Diseases 0.000 abstract description 4
- 230000000474 nursing effect Effects 0.000 abstract description 3
- 230000006866 deterioration Effects 0.000 abstract description 2
- 239000002344 surface layer Substances 0.000 abstract description 2
- 239000000463 material Substances 0.000 description 9
- 238000004026 adhesive bonding Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 230000029663 wound healing Effects 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 238000007598 dipping method Methods 0.000 description 2
- 239000006260 foam Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 235000010410 calcium alginate Nutrition 0.000 description 1
- 229960002681 calcium alginate Drugs 0.000 description 1
- 239000000648 calcium alginate Substances 0.000 description 1
- OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002439 hemostatic effect Effects 0.000 description 1
- 239000000416 hydrocolloid Substances 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- PYOZTOXFQNWBIS-UHFFFAOYSA-N phenol;sodium Chemical compound [Na].OC1=CC=CC=C1 PYOZTOXFQNWBIS-UHFFFAOYSA-N 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
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- Materials For Medical Uses (AREA)
Abstract
The invention discloses a dressing with a pH indicating function and a preparation method thereof, wherein the dressing with the pH indicating function comprises an absorption cotton layer (1) absorbed with a pH indicator. According to the dressing with the PH indicating function, provided by the invention, as the absorption surface layer contains phenol red or phenol red sodium, when the PH value of the wound reaches above 6.5, the absorption cotton layer can change the color, so that a wounded or medical personnel can judge whether the wound is infected according to the color of the absorption cotton layer, take nursing measures in time, avoid the infection deterioration and relieve the pain of the wounded. The preparation method provided by the invention is used for preparing the dressing with the pH indicating function, so that the wound can be rapidly healed, and the wound infection can be prevented.
Description
Technical Field
The invention relates to the technical field of medical instruments and new materials, in particular to a dressing with a pH indicating function and a preparation method thereof.
Background
The dressing is auxiliary materials except main materials for articles, and mainly refers to hemostatic gauze. Traditional dressings are mainly dry gauze and oil gauze. Modern wound dressings include interactive wound dressings, calcium alginate dressings, silver dressings, foam dressings, hydrocolloid dressings, and hydrogel dressings. The dressing in the prior art can play a role in stopping bleeding, resisting bacteria and promoting wound healing after being applied to a wound. However, after the dressing in the prior art is applied to a wound, wound healing or infection conditions cannot be observed, such as infection of the wound, and the wound cannot be found in time; or the wound infection condition can be found only by uncovering the dressing, which is not only troublesome, but also not beneficial to wound healing, and brings certain pain to the wounded.
Disclosure of Invention
The invention aims to provide a dressing with a pH indicating function and a preparation method thereof.
The dressing with the PH indicating function comprises an absorption cotton layer (1) absorbed with a PH indicator.
The dressing with the PH indicating function is also provided with a protective layer (2), and the protective layer (2) is arranged at the bottom of the absorbing cotton layer (1); the area of the protective layer (2) is larger than that of the absorption cotton layer (1), and the absorption cotton layer (1) is arranged at the position, close to the center, of the protective layer (2). The dressing with the PH indicating function is further provided with an adhesive layer (3), the adhesive layer (3) is arranged between the protective layer (2) and the absorbing cotton layer (1), the shape and the area of the adhesive layer (3) are consistent with those of the protective layer (2), and the adhesive layer (3) forms an annular adhesive area around the absorbing cotton layer (1). The dressing with the pH indicating function is further provided with a release paper layer (4), the release paper is attached to the tops of the absorption tissue layer (1) and the gluing area, and the shape and the area of the release paper layer (4) are consistent with those of the gluing layer (3).
The preparation method of the dressing with the pH indicating function, provided by the invention, comprises the following steps: s1, preparing an absorption cotton layer with a pH indicating function; s2, preparing a protective layer, an adhesive layer and a release paper layer; and S3, cutting and attaching the absorption cotton layer, the protective layer, the adhesive layer and the release paper layer to form the dressing with the pH indicating function.
The step of preparing the absorbent cotton layer with the pH indicating function by using the S1 comprises the following steps: s11, a step of dipping the liquid absorbing material in a PH indicator to form the liquid absorbing material with the PH indicating function; s12, a step of drying the liquid absorption material with the pH indication function to form an absorption cotton with the pH indication function; s13, compacting the absorbing cotton to form a lamellar absorbing cotton layer with a pH indicating function; s14, a step of performing film cutting treatment on the absorbent cotton layer with the pH indicating function. The protective layer is made of polyurethane film material. The adhesive layer is made of silica gel or acrylic pressure-sensitive adhesive. The preparation method of the dressing with the pH indicating function further comprises the step of sterilizing the absorption cotton layer with the pH indicating function. The liquid absorbing material is made of needle punched cotton, spunlaced cotton, hot air non-woven fabric or foam material; the PH indicator is phenol red solution, phenol red sodium solution or mixed solution of phenol red and phenol red sodium.
According to the dressing with the PH indicating function, the absorption surface layer contains phenol red or phenol red sodium, and when the PH value of a wound is more than 6.5, the absorption cotton layer can change the color, so that a wounded person or medical personnel can judge whether the wound is infected according to the color of the absorption cotton layer, take nursing measures in time, avoid the deterioration of infection and relieve the pain of the wounded person. The preparation method provided by the invention is used for preparing the dressing with the pH indicating function, so that the wound can be rapidly healed, and the wound infection can be prevented.
Drawings
FIG. 1 is a schematic diagram of a dressing with pH indication according to a first embodiment of the present invention;
FIG. 2 is a schematic diagram of a method for manufacturing a dressing with pH indicating function according to a second embodiment of the present invention;
fig. 3 is a schematic diagram of the steps for preparing a PH indicating absorbent cotton layer in the preparation of a PH indicating dressing according to example two of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example one
The dressing with pH indicator function provided by this embodiment comprises an absorbent cotton layer 1 absorbed with pH indicator. It will be appreciated by those skilled in the art that the PH indicator may employ phenol red or sodium phenol red or a combination of both. It will be appreciated by those skilled in the art that wounds heal well and without infection and are in an acidic state with a PH below 5, whereas when the wound is infected, its PH rises above 6.5, in a mildly alkaline state. The dressing that has PH instruction function that this embodiment provided, because contain phenol red or phenol red sodium in the absorption surface course, when wound PH to reach more than 6.5, absorb continuous layer 1 and can change the colour to whether wounded or medical personnel can judge the wound according to the colour that absorbs continuous layer 1 and infected, in time take to deal with nursing measures, avoid infecting and worsen, alleviate the wounded's misery.
Further, the dressing with PH indication function provided in this embodiment is further provided with a protection layer 2, and the protection layer 2 is disposed at the bottom of the absorption cotton layer 1; the area of the protective layer 2 is larger than that of the absorbent cotton layer 1, and the absorbent cotton layer 1 is arranged at a position, close to the center, of the protective layer 2. As will be understood by those skilled in the art, the protective layer 2 may be made of a polyurethane film material, and has moisture and bacteria permeable functions. When the dressing with the PH indication function provided in the present embodiment is applied to a wound, the absorbent cotton layer 1 is applied to the wound site; the protective layer 2 is applied to the skin around the wound, and the absorbent cotton layer 1 can be applied to the wound position more stably.
Further, the dressing with the PH indication function provided by this embodiment is further provided with an adhesive layer 3, the adhesive layer 3 is disposed between the protective layer 2 and the absorbent cotton layer 1, the shape and the area of the adhesive layer 3 are consistent with those of the protective layer 2, and the adhesive layer 3 forms an annular adhesive area around the absorbent cotton layer 1. As can be understood by those skilled in the art, the adhesive layer 3 can make the absorbent cotton layer 1 better attached to the top of the protective layer 2 at the central position, and can also make the dressing with the PH indicating function provided by this embodiment more firmly attached to the skin around the wound, and the application effect is better.
Further, the dressing with the PH indication function provided by this embodiment is further provided with a release paper layer 4, the release paper is attached to the top of the absorption tissue layer 1 and the gluing area, and the shape and the area of the release paper layer 4 are consistent with those of the adhesive layer 3. It can be understood by those skilled in the art that when the dressing with PH indication function provided in this embodiment is not in use, the release paper is attached on top of the absorbent cotton layer 1 and the adhesive area, so that the dressing with PH indication function provided in this embodiment can be stored and transported conveniently, and the external environment is prevented from contaminating the absorbent cotton layer 1, which causes the adhesive area to decrease in viscosity.
Example two
The embodiment provides a preparation method of a dressing with a pH indicating function, which comprises the following steps:
s1, preparing an absorption cotton layer with a pH indicating function;
s2, preparing a protective layer, an adhesive layer and a release paper layer;
and S3, cutting and attaching the absorption cotton layer, the protective layer, the adhesive layer and the release paper layer to form the dressing with the pH indicating function.
Further, the protective layer is made of a polyurethane film material.
Further, the adhesive layer is made of silica gel or acrylic pressure-sensitive adhesive.
Further, the step S1 of preparing an absorbent cotton layer with PH indicating function comprises:
s11, a step of dipping the liquid absorbing material in a PH indicator to form the liquid absorbing material with the PH indicating function;
s12, a step of drying the liquid absorption material with the pH indication function to form an absorption cotton with the pH indication function;
s13, compacting the absorbing cotton to form a lamellar absorbing cotton layer with a pH indicating function;
s14, a step of performing film cutting treatment on the absorbent cotton layer with the pH indicating function.
It will be appreciated by those skilled in the art that through the above steps, a PH indicating absorbent cotton layer having a size suitable for the manufactured PH indicating dressing can be obtained, thereby facilitating the subsequent manufacture of the PH indicating dressing.
Further, the present embodiment provides a method for preparing a dressing with PH indication function, which further includes a step of performing a sterilization treatment on the absorbent cotton layer with PH indication function. It will be appreciated by those skilled in the art that the prepared dressing with PH indication function may be further packaged for subsequent storage and shipment.
Further, the liquid absorbing material can be needle punched cotton, spunlaced cotton, hot air non-woven fabric or foam material. As can be understood by those skilled in the art, the needle punched cotton, the spunlaced cotton, the hot air non-woven fabric or the foam all have strong water absorption performance, can effectively absorb body fluid exuded from wounds after being made into a dressing, keeps the wounds dry and is not easy to cause infection.
Further, the pH indicator is phenol red solution, phenol red sodium solution or mixed solution of phenol red and phenol red sodium. As can be understood by those skilled in the art, the color of the phenol red solution, the phenol red sodium solution or the mixed solution of phenol red and phenol red sodium changes when the solution meets the liquid with the pH value of more than 6.5, so that the absorption cotton layer formed after the solution is soaked in the absorption cotton material changes the color after the solution absorbs the liquid exuded by wound infection, and the wounded and the medical staff can judge the infection condition of the wound through the color change, so that the wound can be treated in time and the wound can be kept to heal well.
Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (10)
1. A dressing with a pH indicator function, characterized in that it comprises an absorbent cotton layer (1) having a pH indicator adsorbed thereon.
2. A dressing having PH indicating function according to claim 1, wherein a protective layer (2) is further provided, said protective layer (2) being arranged at the bottom of the absorbent cotton layer (1); the area of the protective layer (2) is larger than that of the absorption cotton layer (1), and the absorption cotton layer (1) is arranged at the position, close to the center, of the protective layer (2).
3. A dressing having PH indicating functionality according to claim 2, further comprising an adhesive layer (3), wherein said adhesive layer (3) is arranged between said protective layer (2) and said absorbent cotton layer (1), said adhesive layer (3) having a shape and area corresponding to said protective layer (2), said adhesive layer (3) forming an annular adhesive area around said absorbent cotton layer (1).
4. A dressing having PH indicating function according to claim 3, further comprising a release paper layer (4), said release paper being attached on top of said absorbent tissue layer (1) and said adhesive area, said release paper layer (4) having a shape and area corresponding to said adhesive layer (3).
5. A preparation method of a dressing with a pH indicating function is characterized by comprising the following steps:
s1, preparing an absorption cotton layer with a pH indicating function;
s2, preparing a protective layer, an adhesive layer and a release paper layer;
and S3, cutting and attaching the absorbing cotton layer, the protective layer, the adhesive layer and the release paper layer to form the dressing with the pH indicating function.
6. The method of claim 5, wherein the step of preparing the absorbent cotton layer with PH indicating function by using S1 comprises:
s11, soaking the liquid absorbing material in a pH indicator to form the liquid absorbing material with a pH indicating function;
s12, drying the liquid absorbing material with the pH indicating function to form an absorbing sponge with the pH indicating function;
s13, compacting the absorbing cotton to form a lamellar absorbing cotton layer with a pH indicating function;
s14, a step of performing film cutting treatment on the absorbent cotton layer with the pH indicating function.
7. The method of claim 6, wherein the protective layer is made of polyurethane film.
8. The method of claim 7, wherein the adhesive layer is formed from silicone gel or acrylic pressure sensitive adhesive.
9. The method of claim 8, further comprising the step of sterilizing the absorbent cotton layer with PH indicator.
10. The method for preparing a dressing having a PH indicating function according to claim 9, wherein the liquid absorbing material is needle punched cotton, spunlaced cotton, hot air non-woven fabric or foam material; the PH indicator is phenol red solution, phenol red sodium solution or mixed solution of phenol red and phenol red sodium.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110910642.5A CN115702849A (en) | 2021-08-09 | 2021-08-09 | Dressing with pH indicating function and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110910642.5A CN115702849A (en) | 2021-08-09 | 2021-08-09 | Dressing with pH indicating function and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115702849A true CN115702849A (en) | 2023-02-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110910642.5A Withdrawn CN115702849A (en) | 2021-08-09 | 2021-08-09 | Dressing with pH indicating function and preparation method thereof |
Country Status (1)
| Country | Link |
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| CN (1) | CN115702849A (en) |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5181905A (en) * | 1989-11-28 | 1993-01-26 | Eric Flam | Method of monitoring the condition of the skin or wound |
| US20040044299A1 (en) * | 2002-08-27 | 2004-03-04 | Ryuichi Utsugi | Adhesive dressing |
| CN101327333A (en) * | 2008-07-24 | 2008-12-24 | 鲁建国 | Medical dressing containing microorganism indicator and method for producing the same |
| CN107375996A (en) * | 2017-07-31 | 2017-11-24 | 长沙海润生物技术有限公司 | A kind of Biofunctional dressing and preparation method thereof |
| US20190224363A1 (en) * | 2016-09-08 | 2019-07-25 | Sefar Ag | Indicator dressing and method for indicating a contamination, in particular of a wound |
| CN209347417U (en) * | 2018-10-26 | 2019-09-06 | 苏州汇涵医用科技发展有限公司 | Dressing with wound infection warning function |
| CN210019931U (en) * | 2018-12-18 | 2020-02-07 | 生命之星国际股份有限公司 | Wound dressing with indication function |
| CN211095265U (en) * | 2019-09-18 | 2020-07-28 | 广州中医药大学第一附属医院 | Medical multilayer dressing |
| CN217286299U (en) * | 2021-08-09 | 2022-08-26 | 上海亚澳医用保健品有限公司 | Dressing with PH indicating function |
-
2021
- 2021-08-09 CN CN202110910642.5A patent/CN115702849A/en not_active Withdrawn
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5181905A (en) * | 1989-11-28 | 1993-01-26 | Eric Flam | Method of monitoring the condition of the skin or wound |
| US20040044299A1 (en) * | 2002-08-27 | 2004-03-04 | Ryuichi Utsugi | Adhesive dressing |
| CN101327333A (en) * | 2008-07-24 | 2008-12-24 | 鲁建国 | Medical dressing containing microorganism indicator and method for producing the same |
| US20190224363A1 (en) * | 2016-09-08 | 2019-07-25 | Sefar Ag | Indicator dressing and method for indicating a contamination, in particular of a wound |
| CN107375996A (en) * | 2017-07-31 | 2017-11-24 | 长沙海润生物技术有限公司 | A kind of Biofunctional dressing and preparation method thereof |
| CN209347417U (en) * | 2018-10-26 | 2019-09-06 | 苏州汇涵医用科技发展有限公司 | Dressing with wound infection warning function |
| CN210019931U (en) * | 2018-12-18 | 2020-02-07 | 生命之星国际股份有限公司 | Wound dressing with indication function |
| CN211095265U (en) * | 2019-09-18 | 2020-07-28 | 广州中医药大学第一附属医院 | Medical multilayer dressing |
| CN217286299U (en) * | 2021-08-09 | 2022-08-26 | 上海亚澳医用保健品有限公司 | Dressing with PH indicating function |
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