CN115584313B - Detection kit for detecting infectious pathogen sample - Google Patents
Detection kit for detecting infectious pathogen sample Download PDFInfo
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- CN115584313B CN115584313B CN202211578042.4A CN202211578042A CN115584313B CN 115584313 B CN115584313 B CN 115584313B CN 202211578042 A CN202211578042 A CN 202211578042A CN 115584313 B CN115584313 B CN 115584313B
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- 238000001514 detection method Methods 0.000 title claims abstract description 94
- 244000052769 pathogen Species 0.000 title claims abstract description 20
- 208000015181 infectious disease Diseases 0.000 title claims abstract description 19
- 230000002458 infectious effect Effects 0.000 title claims abstract description 19
- 230000001717 pathogenic effect Effects 0.000 title claims abstract description 19
- 239000007788 liquid Substances 0.000 claims abstract description 107
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 91
- 239000012678 infectious agent Substances 0.000 claims abstract description 9
- 230000000694 effects Effects 0.000 claims abstract description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 39
- 230000007246 mechanism Effects 0.000 claims description 23
- 239000002351 wastewater Substances 0.000 claims description 12
- 238000012360 testing method Methods 0.000 claims description 10
- 230000005484 gravity Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 238000007599 discharging Methods 0.000 description 3
- 239000000284 extract Substances 0.000 description 3
- 208000028774 intestinal disease Diseases 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 208000035473 Communicable disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/20—Mixing the contents of independent containers, e.g. test tubes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a detection kit for detecting an infectious pathogen sample, and belongs to the technical field of detection kits. The utility model provides a detect reagent box for infectious agent sample detects, including box body and hinged joint's lid on the box body, fixedly connected with support column in the box body, the top of support column is connected with the backup pad, is provided with the detection dish in the backup pad, still is provided with electric putter in the box body, and electric putter's top is connected with the holding ring, is provided with the pipe of placing that is circumference evenly distributed on the holding ring, is provided with the reagent pipe in the pipe of placing, and the top of box body rotates and sets up the liquid source casing, and the bottom activity of liquid source casing is provided with the rotation pipe; the invention has convenient use, does not need to manually add reagents or transfer reagents one by using a burette, reduces the labor intensity of operators, improves the detection efficiency, reduces the intervention of the operators, and greatly reduces the leakage or pollution probability of the detection sample, thereby improving the detection accuracy.
Description
Technical Field
The invention relates to the technical field of detection kits, in particular to a detection kit for detecting an infectious pathogen sample.
Background
Intestinal diseases are diseases with high incidence rate at present, infectious pathogens are easy to generate in the intestinal tract, and if the intestinal diseases are not treated timely, the intestinal diseases are easy to harm the health of patients and the health of other people. With the development of the medical and chemical industries, some detection kits which are more convenient to use are rapidly popularized and used for detecting pathogen samples of infectious diseases.
The existing reagent kit generally needs to add reagents into a test tube positioned in the reagent kit one by one through manual operation of a tester, the operation process is slow, then when a sample to be detected and the reagents are mixed in the reagent tube, the mixed reagents need to be transferred to the detection test paper by adopting a pipette or an injector for detection, and when different reagents are extracted, the pipette tip or the injector and the needle need to be cleaned, so that the operation is complex, the time is wasted, and the detection efficiency is low; meanwhile, in the process of transferring the detection sample from the reagent tube to the detection test paper, manual operation is needed, such as improper operation, sample leakage, sample cross contamination and the like can be generated, risks are brought to detection personnel and detection sample safety, and the accuracy of detection samples is reduced.
Disclosure of Invention
The invention aims to solve the problems in the prior art and provides a detection kit for detecting an infectious pathogen sample.
In order to achieve the above purpose, the present invention adopts the following technical scheme:
the utility model provides a detect reagent box for infectious pathogen sample detects, includes box body and hinged joint's lid on the box body, fixedly connected with support column in the box body, the top of support column is connected with the backup pad, be provided with the detection dish in the backup pad, the inside electric putter that still is provided with of box body, electric putter's top is connected with the holding ring, be provided with on the holding ring and be circumference evenly distributed's the pipe of placing, place intraductally and be provided with the reagent pipe, the top of box body rotates and sets up the liquid source casing, the bottom activity of liquid source casing is provided with the rotation pipe, the cover of rotation pipe outside is equipped with the clear water casing, be provided with the liquid feeding pipeline between clear water casing and the reagent pipe.
Preferably, the top of box body is provided with first motor, the output of first motor passes the box body and links to each other with the liquid source casing, be connected with first connecting rod between clear water casing and the holding ring, the first shrinkage pool of matched with has been seted up on liquid feeding pipeline and the liquid source casing, the one end that the clear water casing was kept away from to the liquid feeding pipeline is arranged in the reagent pipe.
Preferably, the first connecting rod comprises two L-shaped rods, the two L-shaped rods are respectively connected with the clean water shell and the positioning ring, and a connecting pipe is slidably arranged between the two L-shaped rods.
Preferably, sliding connection has the piston board in the rotation pipe, be formed with the working cavity between the diapire of piston board and liquid source casing, be provided with feed liquor valve and the drain valve of being connected with the working cavity on rotation pipe and the piston board respectively, drain valve department is connected with flexible pipe, flexible pipe is arranged in the upside of detecting the dish, offer a plurality of and feed liquor valve matched with second shrinkage pool on the clear water casing, second shrinkage pool and first shrinkage pool staggered distribution, and be circumference evenly distributed on the clear water casing.
Preferably, the support plate is connected with a positioning ring through a connecting rod, the positioning ring is fixedly connected with a telescopic pipe, the telescopic pipe comprises a sleeve fixedly connected with the positioning ring and a movable pipe fixedly connected with the piston plate, and the movable pipe is slidably connected in the sleeve.
Preferably, the support plate is provided with a driving mechanism for driving the rotating tube to rotate, the driving mechanism comprises a rotating rod which is arranged on the support plate in a rotating mode, an incomplete gear is connected to the rotating rod, a first gear is connected to the outer side of the incomplete gear in a meshed mode, a first rotating rod is arranged between the first gear and the support plate, a first gear ring is arranged on the outer side of the first gear in a meshed mode, the first gear ring is connected with the rotating tube through a supporting rod, the driving mechanism further comprises a second motor which is fixedly arranged on the support plate, and the output end of the second motor penetrates through the support plate and is connected with the rotating rod.
Preferably, the liquid discharging mechanism is arranged in the rotating tube and is connected with the driving mechanism, the liquid discharging mechanism comprises a second rotating rod which is rotatably arranged on the supporting plate, a second gear which is meshed with the incomplete gear is arranged on the second rotating rod, a first bevel gear is arranged on the second rotating rod, a support plate is fixedly arranged on the supporting plate, a third rotating rod is rotatably connected on the support plate, a second bevel gear which is meshed with the first bevel gear is connected on the third rotating rod, a first connecting plate is connected on the third rotating rod, a second connecting plate is rotatably connected on the first connecting plate through a pin shaft, and one end of the second connecting plate far away from the first connecting plate is movably connected with the piston plate.
Preferably, the rotating rod is provided with a driving gear, the supporting plate is provided with a second gear ring meshed with the driving gear, and the detection disc is arranged on the second gear ring.
Preferably, a plurality of circumferentially staggered detection grooves and wastewater grooves are formed in the detection disc, detection test paper is arranged in the detection grooves, and colorimetric marks are arranged at the detection grooves.
Preferably, the positioning ring is fixedly connected with a shell, the shell is internally and movably connected with a universal ball, the universal ball is connected with the placing pipe through a connecting rod, a second connecting rod is arranged on the outer side of the liquid source shell, one end, far away from the liquid source shell, of the second connecting rod is connected with a rotating ring, a plurality of lugs which are uniformly distributed in circumference are arranged on the rotating ring, and the lugs are movably abutted to the placing pipe.
Compared with the prior art, the invention provides a detection kit for detecting infectious pathogen samples, which has the following beneficial effects:
1. this a detect reagent box for infectious pathogen sample detects through evenly adding the reagent liquid source in making every reagent pipe, and reagent and sample mix, control actuating mechanism and flowing back mechanism operation afterwards, extracts one by one to the reagent solution of mixing in the reagent pipe to make it arrange in the detection dish and detect, need not operating personnel and add or draw the reagent with buret manual one by one, reduce operating personnel intensity of labour, improve detection efficiency, reduce personnel's intervention simultaneously, greatly reduced the probability of detecting sample leakage or pollution, thereby improved the rate of accuracy of detection.
2. According to the detection kit for detecting the infectious pathogen sample, when the liquid inlet valve is aligned with the liquid adding pipeline, the piston plate is controlled to move downwards, so that the piston plate extracts the mixed reagent in the reagent pipe through the liquid inlet valve and the liquid adding pipeline, the mixed reagent enters the working cavity, then the piston plate is controlled to move upwards, the mixed reagent entering the working cavity falls on the detection disc through the liquid outlet valve and the telescopic pipe, and the mixed reagent is detected; when the liquid inlet valve is aligned with the second concave hole, the clean water in the clean water shell can be extracted by the downward movement of the piston plate to enter the working cavity, and when the piston plate moves upwards again, the clean water in the working cavity is discharged through the liquid outlet valve and washes the reagent adhered to the inner part of the telescopic pipe before the telescopic pipe, so that the influence on the detection result of other subsequent sample reagents is avoided.
3. This a detect reagent box for infectious pathogen sample detects, the initiative tooth in the outside meshes with the second ring gear in the backup pad when rotating through the dwang, and the second ring gear drives the detection dish and continuously rotates, makes the detection groove and the waste water groove automatic replacement of arranging the flexible pipe downside in, makes the mixed reagent that falls from flexible pipe department and the waste water after wasing flexible pipe get into detection groove and waste water groove respectively.
4. This a detect reagent box for infectious agent sample detects, the rotation of liquid source casing can drive the rotation ring through the second connecting rod and rotate, and the lug that inboard set up offsets with placing the pipe when the rotation ring rotates, places the pipe and offsets on the holding ring through the universal ball, when the lug no longer offsets with placing the pipe, places the pipe and automatic re-set under the solution gravity of its inside reagent pipe to rock when making the sample in the reagent pipe add the reagent, accelerate its mixing efficiency and the homogeneity of mixing, and then improve detection efficiency and the testing result to the sample.
Drawings
FIG. 1 is a schematic diagram of a first embodiment of the present invention;
FIG. 2 is a schematic diagram of a second embodiment of the present invention;
FIG. 3 is a schematic view of the inside of the case of the present invention;
FIG. 4 is a schematic cross-sectional view of the present invention;
FIG. 5 is an enlarged schematic view of portion A of FIG. 4 in accordance with the present invention;
FIG. 6 is an enlarged schematic view of part B of FIG. 4 in accordance with the present invention;
FIG. 7 is a schematic cross-sectional view of the clean water housing of the present invention;
FIG. 8 is a schematic diagram of the inside of the case of the present invention;
fig. 9 is a schematic view showing an external structure of the support plate of the present invention;
fig. 10 is a schematic cross-sectional structure of the support plate of the present invention;
fig. 11 is a schematic structural view of the test disc of the present invention.
In the figure: 1. a case body; 101. a support column; 102. an electric push rod; 2. a box cover; 3. a support plate; 4. a detection disc; 401. a detection groove; 402. a waste water tank; 403. colorimetric marking; 5. a positioning ring; 501. a housing; 502. a universal ball; 6. placing a tube; 7. a reagent tube; 8. a liquid source housing; 801. a first motor; 802. a first concave hole; 9. a rotary tube; 901. a liquid inlet valve; 902. a liquid outlet valve; 10. a clean water shell; 1001. a second concave hole; 11. a first link; 111. an L-shaped rod; 112. a connecting pipe; 12. a liquid adding pipeline; 13. a piston plate; 14. a telescopic tube; 141. a sleeve; 142. a movable tube; 15. a rotating lever; 151. an incomplete gear; 152. a second motor; 153. a drive gear; 16. a first rotating lever; 161. a first gear; 17. a first ring gear; 18. a second rotating rod; 181. a second gear; 182. a first bevel gear; 19. a support plate; 191. a third rotating rod; 1911. a first connecting plate; 1912. a second connecting plate; 192. a second bevel gear; 20. a second ring gear; 21. a positioning ring; 22. a rotating ring; 221. a second link; 222. and a bump.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments.
In the description of the present invention, it should be understood that the terms "upper," "lower," "front," "rear," "left," "right," "top," "bottom," "inner," "outer," and the like indicate or are based on the orientation or positional relationship shown in the drawings, merely to facilitate description of the present invention and to simplify the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present invention.
Example 1:
referring to fig. 1, fig. 2, fig. 3, fig. 4, fig. 7, fig. 8 and fig. 11, a detection kit for detecting infectious pathogen samples comprises a box body 1 and a box cover 2 hinged on the box body 1, wherein a support column 101 is fixedly connected in the box body 1, the top of the support column 101 is connected with a support plate 3, a detection disc 4 is arranged on the support plate 3, an electric push rod 102 is further arranged in the box body 1, the top of the electric push rod 102 is connected with a positioning ring 5, a placing pipe 6 which is uniformly distributed in circumference is arranged on the positioning ring 5, a reagent pipe 7 is arranged in the placing pipe 6, a liquid source shell 8 is rotatably arranged at the top of the box body 1, a rotating pipe 9 is movably arranged at the bottom of the liquid source shell 8, a clear water shell 10 is sleeved outside the rotating pipe 9, and a liquid adding pipeline 12 is arranged between the clear water shell 10 and the reagent pipe 7.
Specifically, a plurality of reagent pipes 7 in the box body 1 are internally provided with different detection samples, a reagent liquid source is uniformly added in each reagent pipe 7 through matching the control liquid source shell 8 with the liquid adding pipeline 12, the reagents are mixed with the samples, then the mixed reagent solutions in the reagent pipes 7 are extracted one by one and are placed in the detection disc 4 for detection, an operator does not need to manually add or absorb the reagents one by using a buret, the labor intensity of the operator is reduced, the detection efficiency is improved, the intervention of the operator is reduced, the leakage or pollution probability of the detection samples is greatly reduced, and the detection accuracy is improved.
Example 2:
referring to fig. 2, 3, 4, 5 and 7, a detection kit for detecting an infectious pathogen sample is further provided, based on embodiment 1, with a first motor 801 at the top of the box 1, an output end of the first motor 801 penetrates through the box 1 and is connected with the liquid source housing 8, a first connecting rod 11 is connected between the clean water housing 10 and the positioning ring 5, a first concave hole 802 is formed in the liquid supply housing 8 in a matching manner, and one end of the liquid supply conduit 12, far from the clean water housing 10, is disposed in the reagent tube 7.
Specifically, through controlling the operation of the first motor 801, the output end of the first motor 801 drives the liquid source shell 8 to rotate in the box body 1, a first concave hole 802 is formed in the liquid source shell 8, a first concave hole 802 is formed in a plurality of liquid adding pipelines 12 arranged on the clean water shell 10, along with the uniform rotation of the liquid source shell 8 on the clean water shell 10, reagents in the liquid source shell 8 fall through the first concave hole 802 and enter each liquid adding pipeline 12 one by one, finally fall into the reagent tube 7 under the action of gravity, and are mixed with detection samples in the reagent tube 7.
Example 3:
referring to fig. 3, 4, 5 and 8, a detection kit for detecting an infectious agent sample is further provided, based on embodiment 2, in which the first link 11 includes two L-shaped bars 111, the two L-shaped bars 111 are connected to the clean water housing 10 and the positioning ring 5, respectively, and a connection tube 112 is slidably provided between the two L-shaped bars 111.
Specifically, by controlling the electric push rod 102 to shrink, the electric push rod 102 drives the positioning ring 5 to move downwards, and then the positioning ring 5 drives the placing pipe 6 and the reagent pipe 7 inside the placing pipe to move downwards, at the moment, the clear water shell 10 movably arranged with the liquid source shell 8 keeps the height unchanged, the first connecting rod 11 is automatically stretched, and the reagent pipe 7 is convenient to be far away from the liquid adding pipeline 12, so that the reagent pipe 7 is taken out and cleaned.
Example 4:
referring to fig. 2, 3, 4, 5, 7 and 9, a detection kit for detecting an infectious pathogen sample is further provided, based on embodiment 2, with a piston plate 13 slidably connected in a rotating tube 9, a working cavity is formed between the piston plate 13 and a bottom wall of a liquid source housing 8, a liquid inlet valve 901 and a liquid outlet valve 902 connected with the working cavity are respectively arranged on the rotating tube 9 and the piston plate 13, a telescopic tube 14 is connected at the liquid outlet valve 902, the telescopic tube 14 is arranged on the upper side of the detection disc 4, a plurality of second concave holes 1001 matched with the liquid inlet valve 901 are formed in a clear water housing 10, and the second concave holes 1001 and the first concave holes 802 are distributed in a staggered manner and are uniformly distributed on the clear water housing 10 in circumference.
Specifically, when the liquid inlet valve 901 is aligned with the liquid adding pipeline 12, the piston plate 13 is controlled to move downwards, so that the piston plate 13 extracts the mixed reagent in the reagent pipe 7 through the liquid inlet valve 901 and the liquid adding pipeline 12, the mixed reagent enters the working cavity, then the piston plate 13 is controlled to move upwards, the mixed reagent entering the working cavity falls on the detection disc 4 through the liquid outlet valve 902 and the telescopic pipe 14, and the mixed reagent is detected; when the liquid inlet valve 901 is aligned with the second concave hole 1001, the clean water inside the clean water housing 10 can be pumped by the downward movement of the piston plate 13 to enter the working cavity, and when the piston plate 13 moves up again, the clean water entering the working cavity is discharged through the liquid outlet valve 902 and washes the reagent adhered to the interior of the telescopic tube 14 before so as to avoid influencing the detection result of other subsequent sample reagents.
Example 5:
referring to fig. 4 and 8, a detection kit for detecting a sample of infectious agents is further provided, based on embodiment 4, in which a positioning ring 21 is connected to a support plate 3 via a connecting rod, the positioning ring 21 is fixedly connected to a telescopic tube 14, the telescopic tube 14 includes a sleeve 141 fixedly connected to the positioning ring 21 and a movable tube 142 fixedly connected to a piston plate 13, and the movable tube 142 is slidably connected to the sleeve 141.
Specifically, as the piston plate 13 moves up and down, the sleeve 141 of the telescopic tube 14 is fixed by the retainer ring 21, so that the movable tube 142 slides in the sleeve 141 while moving up and down with the piston plate 13.
Example 6:
referring to fig. 2, 3, 4, 5, 6, 7, 8, 9 and 10, a detection kit for detecting a sample of an infectious pathogen is further provided on the support plate 3, a driving mechanism for driving the rotation tube 9 to rotate is provided on the support plate 3, the driving mechanism includes a rotation rod 15 rotatably provided on the support plate 3, an incomplete gear 151 is connected to the rotation rod 15, a first gear 161 is connected to the outer side of the incomplete gear 151 in a meshed manner, a first rotary rod 16 is provided between the first gear 161 and the support plate 3, a first gear ring 17 is provided to the outer side of the first gear 161 in a meshed manner, the first gear ring 17 is connected to the rotation tube 9 through a support rod, the driving mechanism further includes a second motor 152 fixedly provided on the support plate 3, and an output end of the second motor 152 penetrates through the support plate 3 and is connected to the rotation rod 15.
Specifically, by controlling the second motor 152 to operate, the output end of the second motor 152 drives the rotating rod 15 to rotate, the rotating rod 15 drives the incomplete gear 151 to rotate when rotating, the incomplete gear 151 intermittently engages with the first gear 161 on the first rotating rod 16, the first gear 161 intermittently engages with the first gear ring 17, and the first gear ring 17 drives the rotating tube 9 to rotate through the supporting rod when rotating, so that the liquid inlet valve 901 on the rotating tube 9 is aligned with the opening of the liquid adding pipeline 12 or the second concave hole 1001 on the clean water shell 10, and the mixed reagent or clean water is convenient to be extracted and used.
Example 7:
referring to fig. 2, 3, 4, 5, 6, 7, 8, 9 and 10, based on embodiment 6, further, a liquid draining mechanism is disposed in the rotating tube 9 and connected with the driving mechanism, the liquid draining mechanism includes a second rotating rod 18 rotatably disposed on the supporting plate 3, a second gear 181 engaged with the incomplete gear 151 and connected with the second rotating rod 18 is disposed on the second rotating rod 18, a first bevel gear 182 is disposed on the second rotating rod 18, a support plate 19 is fixedly disposed on the supporting plate 3, a third rotating rod 191 is rotatably connected on the support plate 19, a second bevel gear 192 engaged with the first bevel gear 182 is connected on the third rotating rod 191, a first connecting plate 1911 is connected on the third rotating rod 191, a second connecting plate 1912 is rotatably connected on the first connecting plate 1911 through a pin, and one end of the second connecting plate 1912 far from the first connecting plate 1911 is movably connected with the piston plate 13.
Specifically, when the rotating rod 15 rotates to drive the incomplete gear 151 to rotate, after the incomplete gear 151 is meshed with the first gear 161 on the first rotating rod 16, the first gear 161 does not rotate any more, at this time, the incomplete gear 151 is meshed with the second gear 181 on the second rotating rod 18, when the second gear 181 rotates to drive the second rotating rod 18 and the first bevel gear 182 on the outer side to rotate, the first bevel gear 182 is meshed with the second bevel gear 192 on the third rotating rod 191 to drive the second bevel gear 192 to drive the third rotating rod 191 to rotate, and when the third rotating rod 191 rotates to drive the first connecting plate 1911 to rotate, the first connecting plate 1911 drives the second connecting plate 1912 to swing, so that the second connecting plate 1912 pulls the piston plate 13 to reciprocate up and down in the rotating tube 9.
Example 8:
referring to fig. 2, 3, 9, 10 and 11, a detection kit for detecting an infectious agent sample is further provided, based on embodiment 7, with a driving gear 153 provided on the rotation lever 15, a second gear ring 20 engaged with the driving gear 153 provided on the support plate 3, and a detection disk 4 provided on the second gear ring 20.
Further, a plurality of circumferentially staggered detection grooves 401 and wastewater grooves 402 are formed in the detection disc 4, detection test paper is arranged in the detection grooves 401, and colorimetric marks 403 are arranged at the detection grooves 401.
Specifically, when the rotating rod 15 rotates, the driving gear 153 on the outer side is meshed with the second gear ring 20 on the supporting plate 3, the second gear ring 20 drives the detection disc 4 to continuously rotate, so that the mixed reagent falling from the telescopic tube 14 and the waste water after cleaning the telescopic tube 14 respectively enter the detection groove 401 and the waste water groove 402, the mixed reagent entering the detection groove 401 contacts with the internal detection test paper, and the mixed reagent is compared with the corresponding colorimetric mark 403 after being discolored, so that the color-changing detection device is convenient to use; it should be noted that the detection disc 4 may be composed of two half discs, so that the detection disc 4 is convenient to be taken and placed from the second gear ring 20.
Example 9:
referring to fig. 2, 3, 4 and 8, based on the embodiment 2, a detection kit for detecting an infectious pathogen sample is further provided, wherein a housing 501 is fixedly connected to a positioning ring 5, a universal ball 502 is movably connected to the housing 501, the universal ball 502 is connected to a placing tube 6 through a connecting rod, a second connecting rod 221 is disposed on the outer side of the liquid source housing 8, one end of the second connecting rod 221, which is far away from the liquid source housing 8, is connected to a rotating ring 22, a plurality of protrusions 222 which are uniformly distributed circumferentially are disposed on the rotating ring 22, and the protrusions 222 are movably abutted to the placing tube 6.
Specifically, when the liquid source shell 8 evenly injects the reagent into each reagent tube 7, the rotation of the liquid source shell 8 drives the rotating ring 22 to rotate through the second connecting rod 221, the protruding block 222 arranged on the inner side of the rotating ring 22 is propped against the placing tube 6, the placing tube 6 swings on the positioning ring 5 through the universal ball 502, when the protruding block 222 is not propped against the placing tube 6, the placing tube 6 automatically resets under the gravity of the solution of the reagent tube 7 in the placing tube 6, so that the sample in the reagent tube 7 shakes when the reagent is added, the mixing efficiency and the mixing uniformity are accelerated, the detection efficiency and the detection result of the sample are improved, and the problem that the stress shaking amplitude of the placing tube 6 is small, so that the reagent tube 7 cannot collide with the liquid adding pipeline 12 in the placing tube 6 when the reagent tube 7 shakes, and the reagent tube 7 is damaged is caused.
Working principle: different detection samples are stored in a plurality of reagent pipes 7 in the box body 1, the output end of a first motor 801 drives a liquid source shell 8 to rotate in the box body 1, a first concave hole 802 is formed in the liquid source shell 8, a first concave hole 802 is formed in a plurality of liquid adding pipelines 12 arranged on the clear water shell 10, the liquid source shell 8 rotates on the clear water shell 10 at a uniform speed along with the liquid source shell 8, reagents in the liquid source shell 8 fall down through the first concave hole 802 and enter each liquid adding pipeline 12 one by one, finally fall into the reagent pipes 7 under the action of gravity and are mixed with the detection samples in the reagent pipes 7, so that a reagent liquid source is uniformly added into each reagent pipe 7, in the process, the rotation of the liquid source shell 8 drives a rotating ring 22 to rotate through a second connecting rod 221, a convex block 222 arranged on the inner side of the rotating ring 22 is propped against a placing pipe 6, and the placing pipe 6 swings on a positioning ring 5 through a universal ball 502, so that the samples in the reagent pipes 7 are rocked, the mixing efficiency and the mixing uniformity of the samples in the reagent pipes 7 are accelerated, the mixing efficiency and the detection results of the samples are improved; subsequently, the driving mechanism and the liquid discharging mechanism are controlled to operate together, wherein the first concave hole 802 of the liquid source housing 8 is not opposite to the first concave hole 802 of the liquid feeding pipeline 12; by controlling the second motor 152 to operate, the output end of the second motor 152 drives the rotating rod 15 to rotate, the rotating rod 15 drives the incomplete gear 151 to rotate when rotating, the incomplete gear 151 intermittently meshes with the first gear 161 on the first rotating rod 16, the first gear 161 intermittently meshes with the first gear ring 17, the first gear ring 17 drives the rotating pipe 9 to rotate through the supporting rod, further, the liquid inlet valve 901 on the rotating pipe 9 is aligned with the opening of the liquid adding pipeline 12, the incomplete gear 151 is not meshed with the first gear 161 any more, at the moment, the incomplete gear 151 can mesh with the second gear 181, the second gear 181 drives the second rotating rod 18 and the first bevel gear 182 on the outer side to rotate when rotating, the first bevel gear 182 meshes with the second bevel gear 192 on the third rotating rod 191, the second bevel gear 192 drives the third rotating rod 191, the first connecting plate 1911 drives the second connecting plate 1912 to swing when rotating, further, the second connecting plate 1912 pulls the piston plate 13 to move up and down in the rotating pipe 9, the liquid adding valve 13 is controlled by the reciprocating plate 13 to move up and down, and the reagent is led into the liquid mixing chamber 13 through the liquid adding pipeline 13, and the reagent is pumped into the liquid mixing chamber 13 is detected by the liquid mixing chamber 13, and the reagent is pumped by the liquid mixing valve is controlled by the liquid mixing valve 13, and the reagent is pumped by the liquid mixing valve is pumped by the liquid; then the incomplete gear 151 is meshed with the first gear 161 again, the rotating pipe 9 is enabled to continue to rotate and align with the second concave hole 1001 of the clear water shell 10 through the liquid inlet valve 901, then the incomplete gear 151 is meshed with the second gear 181 again, the piston plate 13 is controlled to move up and down, clear water in the clear water shell 10 is pumped into the working cavity by the downward movement of the piston plate 13, when the piston plate 13 moves up again, clear water in the working cavity is discharged through the liquid outlet valve 902, reagent adhered to the inner part of the telescopic pipe 14 before is washed, the detection result of other sample reagents is prevented from being influenced, the driving gear 153 on the outer side is meshed with the second gear ring 20 on the supporting plate 3 when the rotating rod 15 rotates, the second gear ring 20 drives the detecting disc 4 to rotate continuously, the detecting groove 401 originally arranged on the lower side of the telescopic pipe 14 is automatically replaced by the waste water groove 402, and waste water after washing falls into the waste water groove 402 from the telescopic pipe 14. The method is convenient to operate, the reagent is not required to be manually added or sucked one by an operator through the buret, the labor intensity of the operator is reduced, the detection efficiency is improved, meanwhile, the personnel intervention is reduced, the leakage or pollution probability of the detection sample is greatly reduced, and the detection accuracy is improved.
The foregoing is only a preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art, who is within the scope of the present invention, should make equivalent substitutions or modifications according to the technical scheme of the present invention and the inventive concept thereof, and should be covered by the scope of the present invention.
Claims (7)
1. The utility model provides a detect reagent box for infectious pathogen sample detects, includes box body (1) and hinged joint lid (2) on box body (1), a serial communication port, fixedly connected with support column (101) in box body (1), the top of support column (101) is connected with backup pad (3), be provided with on backup pad (3) and detect dish (4), box body (1) inside still is provided with electric putter (102), electric putter (102)'s top is connected with holding ring (5), be provided with on holding ring (5) and be circumference evenly distributed place pipe (6), be provided with reagent pipe (7) in placing pipe (6), the top of box body (1) rotates and sets up liquid source casing (8), the bottom activity of liquid source casing (8) is provided with rotation pipe (9), rotation pipe (9) outside cover is equipped with casing (10), be provided with liquid feeding pipeline (12) between clear water casing (10) and reagent pipe (7);
the top of the box body (1) is provided with a first motor (801), the output end of the first motor (801) penetrates through the box body (1) and is connected with a liquid source shell (8), a first connecting rod (11) is connected between the clear water shell (10) and the positioning ring (5), a first concave hole (802) matched with the liquid source shell (8) is formed in the liquid adding pipeline (12), and one end, far away from the clear water shell (10), of the liquid adding pipeline (12) is arranged in the reagent tube (7);
a piston plate (13) is connected in a sliding manner in the rotating pipe (9), a working cavity is formed between the piston plate (13) and the bottom wall of the liquid source shell (8), a liquid inlet valve (901) and a liquid outlet valve (902) which are connected with the working cavity are respectively arranged on the rotating pipe (9) and the piston plate (13), a telescopic pipe (14) is connected at the liquid outlet valve (902), the telescopic pipe (14) is arranged on the upper side of the detection disc (4), a plurality of second concave holes (1001) matched with the liquid inlet valve (901) are formed in the clear water shell (10), and the second concave holes (1001) are distributed in a staggered manner with the first concave holes (802) and are uniformly distributed on the clear water shell (10) in circumference;
the support plate (3) is connected with a positioning ring (21) through a connecting rod, the positioning ring (21) is fixedly connected with the telescopic pipe (14), the telescopic pipe (14) comprises a sleeve (141) fixedly connected with the positioning ring (21) and a movable pipe (142) fixedly connected with the piston plate (13), and the movable pipe (142) is slidably connected in the sleeve (141).
2. A test kit for the detection of infectious agent samples according to claim 1, characterized in that the first connecting rod (11) comprises two L-shaped rods (111), the two L-shaped rods (111) are respectively connected with the clean water housing (10) and the positioning ring (5), and a connecting pipe (112) is slidably arranged between the two L-shaped rods (111).
3. A detection kit for detecting a sample of infectious agents according to claim 2, characterized in that the support plate (3) is provided with a driving mechanism for driving the rotation tube (9) to rotate, the driving mechanism comprises a rotating rod (15) rotatably arranged on the support plate (3), an incomplete gear (151) is connected to the rotating rod (15), a first gear (161) is connected to the outer side of the incomplete gear (151) in a meshed manner, a first rotating rod (16) is arranged between the first gear (161) and the support plate (3), a first gear ring (17) is arranged to the outer side of the first gear (161) in a meshed manner, the first gear ring (17) is connected with the rotation tube (9) through a supporting rod, the driving mechanism further comprises a second motor (152) fixedly arranged on the support plate (3), and the output end of the second motor (152) penetrates through the support plate (3) and is connected with the rotating rod (15).
4. A detection kit for detecting an infectious pathogen sample according to claim 3, wherein a liquid draining mechanism is arranged in the rotating tube (9), the liquid draining mechanism is connected with the driving mechanism, the liquid draining mechanism comprises a second rotating rod (18) rotatably arranged on the supporting plate (3), a second gear (181) meshed with the incomplete gear (151) is arranged on the second rotating rod (18), a first bevel gear (182) is arranged on the second rotating rod (18), a supporting plate (19) is fixedly arranged on the supporting plate (3), a third rotating rod (191) is rotatably connected on the supporting plate (19), a second bevel gear (192) meshed with the first bevel gear (182) is connected on the third rotating rod (191), a first connecting plate (1911) is connected on the third rotating rod (191), a second connecting plate (1912) is rotatably connected on the first connecting plate (1911) through a pin shaft, and one end, far away from the first connecting plate (1911), of the second connecting plate (1912) is movably connected with the first connecting plate (13).
5. The detection kit for detecting infectious agent samples according to claim 4, wherein a driving gear (153) is arranged on the rotating rod (15), a second gear ring (20) in meshed connection with the driving gear (153) is arranged on the supporting plate (3), and the detection disc (4) is arranged on the second gear ring (20).
6. The detection kit for detecting infectious agent samples according to claim 5, wherein the detection disc (4) is provided with a plurality of circumferentially staggered detection grooves (401) and wastewater grooves (402), detection test paper is arranged in the detection grooves (401), and colorimetric marks (403) are arranged at the detection grooves (401).
7. The detection kit for detecting infectious pathogen samples according to claim 6, wherein the positioning ring (5) is fixedly connected with a shell (501), a universal ball (502) is movably connected in the shell (501), the universal ball (502) is connected with the placing tube (6) through a connecting rod, a second connecting rod (221) is arranged on the outer side of the liquid source shell (8), one end, far away from the liquid source shell (8), of the second connecting rod (221) is connected with a rotating ring (22), a plurality of lugs (222) which are uniformly distributed in circumference are arranged on the rotating ring (22), and the lugs (222) are movably abutted against the placing tube (6).
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| CN118146932A (en) * | 2024-05-08 | 2024-06-07 | 山东大学齐鲁医院德州医院(德州市人民医院) | A lung cancer detection kit |
| CN119660126B (en) * | 2025-02-20 | 2025-05-02 | 潍坊市检验检测中心 | A detection kit for nicotinoid insecticides in ginger |
| CN120214355B (en) * | 2025-05-28 | 2025-08-15 | 潍坊御俸食品有限公司 | Automatic pretreatment equipment and method for food heavy metal detection sample |
| CN120846982B (en) * | 2025-08-21 | 2026-01-27 | 中国人民解放军总医院第二医学中心 | Kit for acute kidney injury detection |
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