CN115554194B - Whitening and freckle-removing cream and preparation method thereof - Google Patents

Abstract

This application relates to the field of cosmetics, and specifically discloses a whitening and freckle-removing cream, including the following components: antioxidant A; butylene glycol; erythritol; nicotinamide; sodium hyaluronate; carbomer; p-hydroxyacetophenone ; Isononyl Isononanoate; Jojoba Seed Oil; Dimethicone; Emulsifier; Squalane; Tocopheryl Acetate; Ascorbyl Tetraisopalmitate; 1,2‑Hexanediol; amino acid; humectant; arginine ferulate; 1‑methylhydantoin‑2‑imide; diglucosylgallic acid; antioxidant B; whitening agent; the rest is water; among them, anti Oxidant A includes bifid yeast fermentation product filtrate, p-hydroxyacetophenone, butanediol and 1,2-hexanediol; whitening agent includes hydrolyzed prunus japonica, strawberry saxifrage extract and water. The application has the advantages of better removing melanin and improving the whitening and freckle-removing efficacy of the freckle-removing cream.

Description

Whitening and freckle-removing cream and preparation method thereof

technical field

The application relates to the field of cosmetics, more specifically, it relates to a whitening and freckle-removing cream and a preparation method thereof.

Background technique

The skin is a function that can protect the internal tissues and organs of the human body from damage, prevent the loss of water in the body, and prevent harmful substances from invading the human body. Therefore, the skin is an important tissue of the human body, and it is also a symbol that directly expresses human health and aging.

However, with age, the body's metabolism weakens accordingly, and the ability to restore melanin also weakens, and melanin is deposited in the lower layer of the skin; in addition, the accelerated pace of life, irregular work and rest, frequent use of electronic products and some Cosmetics containing heavy metals will also increase the formation of melanin.

At present, there are many skin care products about freckle-removing function on the market, such as various freckle-removing creams, but existing freckle-removing creams cannot remove melanin well, so that the freckle-removing effect is not very obvious, thereby affecting people's lives. Therefore, there is still room for improvement.

Contents of the invention

In order to better remove melanin and improve the whitening and freckle-removing effect of the freckle-removing cream, the application provides a whitening and freckle-removing cream and a preparation method thereof, and adopts the following technical scheme:

In the first aspect, the present application provides a whitening and freckle-removing cream, which adopts the following technical scheme:

A whitening and freckle-removing cream, comprising the following components by mass percentage:

Antioxidant A 9-10%; Butylene Glycol 1-2%; Erythritol 1-2%; Nicotinamide 1-2%; Sodium Hyaluronate 0.1-0.3%; Carbomer 0.1-0.2%; Acetophenone 0.1-0.2%; Isononyl Isononanoate 3-5%; Jojoba Seed Oil 1-2%; Dimethicone 1-2%; Emulsifier 1-2%; Squalane 1-3%; Tocopheryl Acetate 0.2-0.4%; Ascorbyl Tetraisopalmitate 0.2-0.3%; 1,2-Hexanediol 0.1-0.2%; Arginine 0.15-0.2%; Ferulate 0.1-0.3%; 1-Methylhydantoin-2-imide 0.6-0.8%; Diglucosyl gallic acid 0.2-0.4%; Antioxidant B 4-6%; Whitening agent 1- 3%; the rest is water; the total mass percentage is 100%;

Wherein, the antioxidant A comprises the following components in mass percent:

Bifid yeast fermentation product filtrate 95-98%;

p-Hydroxyacetophenone 0.6-0.7%;

Butanediol 0.5-0.7%;

1,2-hexanediol 0.6-3.9%;

The whitening agent includes hydrolyzed European plum, strawberry saxifrage extract and water, and the hydrolyzed European plum and strawberry saxifrage extract respectively account for 0.3-0.5% and 0.1-0.2% by mass of the whitening agent, and the rest is water.

By adopting the above-mentioned technical scheme, the filtrate of the fermented product of Bifida yeast contains various metabolites, polysaccharides, proteins, polypeptides, amino acids, minerals, acids and other nutrients, which nourish the skin, promote metabolism, and provide the basis for skin protein synthesis The ingredients play the role of moisturizing, anti-oxidation and whitening; hydrolyzed European plum has the effect of whitening and lightening spots; the extract of strawberry saxifrage strongly inhibits elastase and collagenase, and has the effect of anti-oxidation and anti-aging. Erythritol can penetrate into the skin, retain the moisture on the skin well, and has obvious moisturizing and water absorption properties.

Therefore, the present application uses the bifid yeast fermentation product filtrate, hydrolyzed prunus prunus, strawberry saxifrage extract and erythritol to cooperate with each other, which is beneficial to improve the whitening and freckle-removing effect of the whitening and freckle-removing cream. This is due to the flavonoid glycosides contained in the strawberry saxifrage extract, which can affect the production of melanin by inhibiting the activity of T cells and dopa oxidase, and the polysaccharides, proteins, polypeptides, and amino acids in the filtrate of the fermentation product of bifid yeast , minerals, acids and other ingredients, combined with hydrolyzed European plum, can complex copper ions in the active site of tyrosinase, thereby inhibiting the activity of tyrosinase; and erythritol can combine strawberry saxifrage extract with A variety of active ingredients in the filtrate of the fermentation product of bifid yeast penetrate into the skin quickly without affecting skin cells, and combine with tyrosine that causes melanin production, effectively block the activity of tyrosine and the production of melanin, and accelerate melanin Decomposition and elimination, so that the freckle effect of whitening and freckle cream can be greatly improved.

Preferably, the preparation method of the strawberry saxifrage extract is as follows:

Weigh strawberry saxifrage, crush it into a coarse powder, add 6-8 times the volume of 80% ethanol to reflux extract 2-3 times, each time for 1-2 hours, filter, combine the filtrates, recover ethanol under reduced pressure, concentrate the remaining liquid, Sequentially use 4-5 times the volume of petroleum ether and ethyl acetate to extract 2-3 times each, combine the ethyl acetate extracts, evaporate to dryness under reduced pressure, and obtain the strawberry saxifrage extract.

By adopting the above-mentioned technical scheme, the strawberry saxifrage extract prepared by the above-mentioned method has higher purity, because the quercetin-5-O-glucoside contained in the strawberry saxifrage extract makes the catalysis of elastase The structure of the active center is changed or covered, resulting in a decrease in the activity of elastase, which is beneficial to improving the anti-wrinkle effect of the whitening and freckle-removing cream.

Preferably, the erythritol mass percentage of the strawberry saxifrage extract is 25-30%.

By adopting the above-mentioned technical scheme, if the content of strawberry saxifrage extract is too much, erythritol cannot quickly penetrate into the skin and easily affect skin cells, and if the content of strawberry saxifrage extract is too small, it will not achieve good results The effect of whitening and freckle removal. Therefore, a specific ratio of strawberry saxifrage extract and erythritol is used to cooperate with each other, so that the freckle removal effect of the whitening and freckle removing cream can reach the best.

Preferably, the whitening agent also includes the following components in mass percentage:

Butanediol 45-50%;

Arbutin 0.4-0.5%;

Citric acid 0.4-0.6%;

Sodium sulfite 0.3-0.5%;

Acetyl tyrosine 0.1-0.2%;

Peony root extract 0.07-0.09%;

Aminopropanol ascorbyl phosphate 0.04-0.06%;

Scutellaria baicalensis root extract 0.03-0.05%;

Glutathione 0.004-0.006%.

By adopting the above technical scheme, arbutin can inhibit the activity of tyrosinase in the body and prevent the formation of melanin, thereby reducing skin pigmentation, removing spots and freckles; citric acid can accelerate the renewal of cutin, and help the skin to peel off melanin , shrink pores, dissolve blackheads; acetyltyrosine can induce tyrosinase, thereby reducing melanin production; peony root extract can prevent melanin production, and can prevent freckles; aminopropanol ascorbyl phosphate can inhibit skin Abnormal pigmentation on the skin; Scutellaria baicalensis root extract can inhibit elastase, interfere with secretion, and eliminate free radicals, thereby increasing skin metabolism, increasing skin elasticity and wrinkle resistance, and anti-aging. Therefore, the whitening and freckle-removing effect of the whitening and freckle-removing cream is further improved by using the above-mentioned substances in a specific ratio.

Preferably, the whitening and freckle-removing cream also includes the following components in mass percentage:

Glycyrrhiza glabra root extract 0.002-0.003%;

Cyclodextrin 0.08-0.10%.

By adopting the above-mentioned technical scheme, the licorice root extract has strong anti-oxidation activity, the functions of skin depigmentation and lightening of spots, can be used for whitening, sterilization, lightening of spots, and has the effect of soothing the skin. The cyclodextrin wraps the licorice root extract in it, which makes the activity of the licorice root extract more stable, so that the whitening and freckle-removing cream has a longer-lasting whitening and freckle-removing effect.

Preferably, the antioxidant B includes the following components in mass percentage:

Ellagic acid 26-30%;

Butanediol 35-40%;

1,2-hexanediol 0.1-0.2%;

Ethylhexylglycerin 0.1-0.2%;

Water 30-35%.

Preferably, the emulsifier comprises the following components in mass percent:

Cetearyl Alcohol 76-80%;

Cetearyl Glucoside 18.5-19.6%;

Glucose 0.1-0.3%;

Water 0.7-5.9%.

By adopting the above-mentioned technical scheme and using the above-mentioned substances in a specific ratio, the whitening and freckle-removing cream can penetrate into the skin more easily, and the moisturizing effect of the whitening and freckle-removing cream can also be enhanced, the texture is refreshing, and the whitening and freckle-removing cream is easier to apply on the skin s surface.

In the second aspect, the present application provides a preparation method of a whitening and freckle-removing cream, which adopts the following technical scheme:

A preparation method of whitening and freckle-removing cream, comprising the following steps:

S1: Weigh the raw materials Antioxidant A, Butylene Glycol, Erythritol, Niacinamide, Sodium Hyaluronate, Carbomer, p-Hydroxyacetophenone and water according to the formula, add them to the main pot and stir to heat to 80-85 ℃, homogenize to fully dissolve it, and obtain the mixture A;

S2: Then weigh isononyl isononanoate, jojoba seed oil, polydimethylsiloxane, emulsifier, squalane, tocopheryl acetate and ascorbyl tetraisopalmitate, and add them to the oil phase in sequence Heat it in the pot to 83-85°C, pump it into the main pot after completely dissolving, homogenize for 5-8 minutes, keep warm for 30-35 minutes, and get the mixture B;

S3: Then start to cool down to 45-50°C, add raw materials 1,2-hexanediol and arginine into the main pot, stir evenly, and cool down to 40-43°C;

S4: Continue to add raw materials arginine ferulate, 1-methylhydantoin-2-imide, diglucosyl gallic acid, antioxidant B and whitening agent, stir evenly, continue to stir and cool down to 36 At -38°C, whitening and freckle-removing cream can be obtained.

By adopting the above technical scheme, the whitening and freckle-removing cream prepared by the above-mentioned preparation method has better whitening and freckle-removing effect, and the components can be fully mixed evenly, which is beneficial to improve the freckle-removing effect of the whitening and freckle-removing cream.

In summary, the present application includes at least one of the following beneficial technical effects:

1. This application uses the bifid yeast fermentation product filtrate, hydrolyzed European plum, strawberry saxifrage extract and erythritol to cooperate with each other, which is beneficial to improve the whitening and freckle-removing effect of the whitening and freckle-removing cream. This is due to the flavonoid glycosides contained in the strawberry saxifrage extract, which can affect the production of melanin by inhibiting the activity of T cells and dopa oxidase, and the polysaccharides, proteins, polypeptides, and amino acids in the filtrate of the fermentation product of bifid yeast , minerals, acids and other ingredients, combined with hydrolyzed European plum, can complex copper ions in the active site of tyrosinase, thereby inhibiting the activity of tyrosinase; and erythritol can combine strawberry saxifrage extract with A variety of active ingredients in the filtrate of bifid yeast fermentation products penetrate into the skin without affecting skin cells, and combine with tyrosine that causes melanin production, effectively block the activity of tyrosine and the production of melanin, and accelerate melanin Decomposition and elimination, so that the freckle effect of whitening and freckle cream can be greatly improved.

2. The strawberry saxifrage extract prepared by the above method has a relatively high purity. Due to the quercetin-5-O-glucoside contained in the strawberry saxifrage extract, the catalytic active center structure of elastase occurs Altered or covered up, resulting in a decrease in the activity of elastase, which is beneficial to improve the anti-wrinkle effect of the whitening and freckle-removing cream.

3. Using a specific ratio of strawberry saxifrage extract and erythritol to cooperate with each other is beneficial to further improve the freckle removing effect of the whitening and freckle removing cream.

Detailed ways

The present application will be described in further detail below in conjunction with the examples.

Preparation Example 1

A preparation method of antioxidant A. At normal temperature, respectively add bifid yeast fermentation product filtrate, butanediol, p-hydroxyacetophenone and 1,2-hexanediol into a stirring tank, and stir at a speed of 50r/min Uniform, that is, the antioxidant A is prepared.

Preparation example 2-3

The difference from Preparation Example 1 is that the dosage of each component is different from that of Preparation Example 1, and the dosage of each component in Preparation Example 3 is not within the scope of protection of this application.

Preparation Example 4

The difference from Preparation Example 2 is that the filtrate of the fermented product of Bifida yeast is replaced with an equal amount of 1,2-hexanediol.

The components and dosages of Preparation Examples 1-4 are shown in Table 1, and the unit of dosage is kg.

Table 1 Antioxidant A

Preparation Example 5

A preparation method of a whitening agent. At normal temperature, hydrolyzed prunus praecox, strawberry saxifrage extract and water are respectively added into a stirring kettle, and stirred evenly at a speed of 80 r/min to prepare the whitening agent.

Preparation example 6-7

The difference with Preparation Example 5 is that the dosage of each component is different from that of Preparation Example 4, and the dosage of each component in Preparation Example 7 is not within the scope of protection of this application.

Preparation example 8

The difference with Preparation Example 6 is:

Whitening agents also include butylene glycol, arbutin, citric acid, sodium sulfite, acetyltyrosine, peony root extract, aminopropanol ascorbyl phosphate, scutellaria baicalensis root extract, and glutathione.

Preparation Example 9

The difference with Preparation Example 8 is that the amount of each component is different from that of Preparation Example 6.

Preparation Example 10

The difference from Preparation Example 6 is that the hydrolyzed European plum is replaced by an equal amount of water.

Preparation Example 11

The difference from Preparation Example 6 is that the strawberry saxifrage extract is replaced with an equal amount of water.

The components and dosages in Preparation Examples 5-11 are shown in Table 2, and the unit of dosage is kg.

Table 2 Whitening agent

Preparation Example 12

An antioxidant B is prepared by adding ellagic acid, butanediol, 1,2-hexanediol, ethylhexylglycerin and water into a stirring tank at room temperature and stirring evenly at a speed of 100r/min. Antioxidant B.

Preparation Example 13-14

The difference from Preparation Example 12 is that the dosage of each component is different from that of Preparation Example 12, and the dosage of each component in Preparation Example 14 is not within the protection scope of the present application.

The components and dosage of Preparation Examples 12-14 are shown in Table 3, and the unit of dosage is kg.

Table 3 Antioxidant B

Preparation Example 15

An emulsifier, which is prepared by adding cetearyl alcohol, cetearyl glucoside, glucose and water into a stirring tank and stirring evenly at a speed of 150 r/min.

Preparation Example 16-17

The difference with Preparation Example 15 is that the dosage of each component is different from that of Preparation Example 15, and the dosage of each component in Preparation Example 17 is not within the scope of protection of this application.

The components and consumption of Preparation Example 15-17 are shown in Table 4

Table 4 Emulsifier

Example 1

This embodiment discloses a whitening and freckle-removing cream, which includes the following components:

Antioxidant A; Butylene Glycol; Erythritol; Niacinamide; Sodium Hyaluronate; Carbomer; 4-Hydroxyacetophenone; Isononyl Isononanoate; Jojoba Seed Oil; Dimethicone; Emulsifier; Squalane; Tocopheryl Acetate; Ascorbyl Tetraisopalmitate; 1,2-Hexanediol; Arginine; Arginine Ferulate; 1-Methylhydantoin-2 - imide; diglucosyl gallic acid; antioxidant B; whitening agent; the rest is water;

Wherein, the antioxidant A prepared in Preparation Example 1 is used as the antioxidant A; the whitening agent prepared in Preparation Example 5 is used as the whitening agent; the antioxidant B prepared in Preparation Example 12 is used as the antioxidant B; the emulsifier is prepared in Preparation Example 12. 15 The emulsifier prepared.

This embodiment discloses a preparation method of a whitening and freckle-removing cream, comprising the following steps:

S1: Weigh the raw materials antioxidant A, butylene glycol, erythritol, nicotinamide, sodium hyaluronate, carbomer, p-hydroxyacetophenone and water according to the formula, add them to the main pot in turn, stir and heat to 80°C, Homogenize to make it fully dissolved to obtain the mixture A;

S2: Then weigh isononyl isononanoate, jojoba seed oil, polydimethylsiloxane, emulsifier, squalane, tocopheryl acetate and ascorbyl tetraisopalmitate, and add them to the oil phase pot in sequence Heat it to 83°C, pump it into the main pot after it is completely dissolved, homogenize it at a speed of 100r/min for 5 minutes, and keep it warm for 30 minutes to obtain the mixture B;

S3: Then start to cool down to 45°C, add the raw materials 1,2-hexanediol and arginine respectively into the main pot, stir evenly at a speed of 80r/min, stir and cool down to 40°C;

S4: Continue to add raw materials arginine ferulate, 1-methylhydantoin-2-imide, diglucosylgallic acid, antioxidant B and whitening agent, and stir evenly at a speed of 120r/min , continue to stir and cool down to 36°C to obtain whitening and freckle-removing cream.

Example 2

The difference from Example 1 is that: the antioxidant A prepared in Preparation Example 2 is used for antioxidant A; the whitening agent prepared in Preparation Example 6 is used for the whitening agent; the antioxidant B prepared in Preparation Example 13 is used for antioxidant B ; The emulsifier prepared in Preparation Example 16 is used as the emulsifier.

A preparation method of whitening and freckle-removing cream, comprising the following steps:

S1: Weigh the raw materials antioxidant A, butanediol, erythritol, nicotinamide, sodium hyaluronate, carbomer, p-hydroxyacetophenone and water according to the formula, add them to the main pot in turn, stir and heat to 85°C, Homogenize to make it fully dissolved to obtain the mixture A;

S2: Then weigh isononyl isononanoate, jojoba seed oil, polydimethylsiloxane, emulsifier, squalane, tocopheryl acetate and ascorbyl tetraisopalmitate, and add them to the oil phase pot in sequence Heat it to 85°C, pump it into the main pot after it is completely dissolved, homogenize it at a speed of 100r/min for 8 minutes, and keep it warm for 35 minutes to obtain the mixture B;

S3: Then start to cool down to 50°C, add the raw materials 1,2-hexanediol and arginine respectively into the main pot, stir evenly at a speed of 80r/min, stir and cool down to 43°C;

S4: Continue to add raw materials arginine ferulate, 1-methylhydantoin-2-imide, diglucosylgallic acid, antioxidant B and whitening agent, and stir evenly at a speed of 120r/min , continue to stir and cool down to 38°C to obtain whitening and freckle-removing cream.

Example 3

The difference from Example 2 is that: the antioxidant A prepared in Preparation Example 3 is used for antioxidant A; the whitening agent prepared in Preparation Example 7 is used for the whitening agent; the antioxidant B prepared in Preparation Example 14 is used for antioxidant B ; The emulsifier prepared in Preparation Example 17 is used as the emulsifier. That is, the amount of each component in Example 3 is not within the scope of protection of the present application.

Example 4

The difference from Example 2 is that the whitening agent is the whitening agent prepared in Preparation Example 8, that is, the whitening agent also includes butanediol, arbutin, citric acid, sodium sulfite, acetyltyrosine, peony root extract, amino Propyl Ascorbyl Phosphate, Scutellaria Baicalensis Root Extract, Glutathione.

Example 5

The difference from Example 2 is that the whitening agent prepared in Preparation Example 9 is used as the whitening agent, that is, the amount of each component in the whitening agent is different from that in Example 4.

Each component and dosage in Examples 1-5 are shown in Table 5, and the unit of dosage is kg.

table 5

Example 6

The difference with embodiment 5 is:

The preparation method of strawberry saxifrage extract is as follows:

Weigh strawberry saxifrage, crush it into a coarse powder, add 6 times the volume of 80% ethanol to reflux extraction twice, each time for 1 hour, filter, combine the filtrate, recover ethanol under reduced pressure, concentrate the remaining liquid, and use 4 times the volume Petroleum ether and ethyl acetate were extracted twice respectively, the ethyl acetate extracts were combined, and evaporated to dryness under reduced pressure to obtain the strawberry saxifrage extract.

Example 7

The difference with embodiment 5 is:

The preparation method of strawberry saxifrage extract is as follows:

Weigh strawberry saxifrage, crush it into a coarse powder, add 8 times the volume of 80% ethanol to reflux extraction for 3 times, each time for 2 hours, filter, combine the filtrate, recover ethanol under reduced pressure, concentrate the remaining liquid, and use 5 times the volume of Petroleum ether and ethyl acetate were extracted 3 times respectively, the ethyl acetate extracts were combined, and evaporated to dryness under reduced pressure to obtain the strawberry saxifrage extract.

Example 8

The difference from Example 7 is that the mass percentage of erythritol in the strawberry saxifrage extract is 25%.

Example 9

The difference from Example 7 is that the mass percentage of erythritol in the strawberry saxifrage extract is 30%.

Comparative example 1

The difference from Example 2 is that the antioxidant A prepared in Preparation Example 4 was used, that is, no bifid yeast fermentation product filtrate was added to the whitening and freckle-removing cream.

Comparative example 2

The difference from Example 2 is that the whitening agent prepared in Preparation Example 10 is used as the whitening agent, that is, no hydrolyzed Prunus prunus is added to the whitening and freckle-removing cream.

Comparative example 3

The difference from Example 2 is that the whitening agent prepared in Preparation Example 11 is used, that is, no strawberry saxifrage extract is added to the whitening and freckle-removing cream.

Comparative example 4

The difference with Example 2 is: replace erythritol with an equal amount of water.

Experiment 1 Freckle removal effect test

This experiment detects respectively the freckle removing effect of the whitening and freckle removing cream prepared above, and the detection method is as follows:

A total of 120 female volunteers aged 20-50 were selected and randomly divided into 12 groups with 10 people in each group. Tested instruments: German CK multi-probe skin test system MPA9, melanin and hemoglobin test probe (Mexamter MX18). The skin melanin content is tested by an instrument. If the content decreases, the whitening and freckle removing cream is effective in removing freckles. If the content increases or remains unchanged, the whitening and freckle removing cream is ineffective for freckle removing.

After cleansing, apply the whitening and anti-freckle cream to the face until it is absorbed without washing; use it 3 times a week for 30 consecutive days; The measurement was started after sitting quietly in the room (temperature 20±1°C, humidity 55±3) for 30 minutes. Select the 4*4cm area in the middle of the right face of each subject, and use the probe to test the average melanin content of the four corners of the area and the 5 positions in the middle. Then, on the 15th and 30th day after trying the whitening and freckle-removing cream, the average melanin content of each group of people was tested according to the above method.

Relative reduction of melanin = average melanin content on day 30 - average melanin content before testing.

Experiment 2 Tyrosinase activity inhibition test

According to the "Cosmetics-Tyrosinase Activity Inhibition Test Method (T/SHRH015-2018)", the tyrosinase inhibition rate (%) and the inhibition rate of the whitening and freckle cream prepared in the above examples and comparative examples were detected respectively. The higher the value, the better the whitening effect of the whitening and freckle removing cream.

Experiment 3 DPPH-free radical scavenging experiment

According to "Cosmetics - Free Radical (DPPH) Scavenging Experimental Method (T/SHRH006-2018)", the scavenging rate (%) of DPPH free radicals of the whitening and freckle creams prepared in the above examples and comparative examples were tested respectively. The higher the scavenging rate The higher the value, the better the anti-wrinkle effect of the whitening and freckle-removing cream.

The above experimental results are shown in Table 6.

Table 6

According to the data of Comparative Examples 1-4 in Table 6 compared with Example 2 respectively, it can be obtained that in Comparative Example 1, the whitening and freckle cream did not add the bifid yeast fermentation product filtrate, in Comparative Example 2, hydrolyzed European plum was not added, and in Comparative Example 3, there was no Add strawberry saxifrage extract, no erythritol was added in Comparative Example 4, but in Example 3, the bifid yeast fermentation product filtrate, hydrolyzed European plum, strawberry saxifrage extract and erythritol were added at the same time, the embodiment The whitening and freckle-removing creams in 3 have better whitening and freckle-removing effects than Comparative Examples 1-4, indicating that the addition of bifid yeast fermentation product filtrate, hydrolyzed European plum, strawberry saxifrage extract and erythritol cooperate with each other, which is beneficial to improve the whitening effect. Freckle removal effect of freckle cream.

According to the data of Examples 4-5 in Table 6 compared with the data of Example 2 respectively, it can be obtained that in Examples 4-5, on the basis of Example 2, butylene glycol, arbutin, and lemon have also been added in the whitening agent. Acid, sodium sulfite, acetyltyrosine, peony root extract, aminopropanol ascorbyl phosphate, Scutellaria baicalensis root extract, glutathione, the freckle-removing effect of whitening and freckle-removing cream in embodiment 4-5 is higher than embodiment 2, illustrates Butanediol, arbutin, citric acid, sodium sulfite, acetyltyrosine, peony root extract, aminopropanol ascorbyl phosphate, scutellaria baicalensis root extract, and glutathione are added to the whitening agent to cooperate with each other, which is beneficial to further improve the whitening effect. Freckle-removing effect of whitening and freckle-removing cream.

According to the data of Example 6-7 in Table 6 compared with the data of Example 5 respectively, the strawberry saxifrage extract in Example 6-7 is prepared by the method of the present application. Compared with Example 5, the implementation The anti-wrinkle effect of the whitening and spot-removing cream in example 6-7 is greatly improved, and this is because the strawberry saxifrage extract prepared by the method of the present application has a higher purity, which is conducive to reducing the activity of elastase, thereby making The anti-wrinkle effect of whitening and freckle cream has been greatly improved.

According to the data of Examples 8-9 in Table 6 compared with the data of Example 7 respectively, Examples 8-9 limit the proportioning of the strawberry saxifrage extract and erythritol, compared to Example 7, The freckle-removing effect of the whitening and freckle-removing cream in Examples 8-9 is improved, which shows that the combination of a specific ratio of strawberry saxifrage extract and erythritol can make the freckle-removing effect of the whitening and freckle-removing cream reach the best.

All of the above are preferred embodiments of the application, and are not intended to limit the protection scope of the application. Therefore, all equivalent changes made according to the structure, shape, and principle of the application should be covered by the protection scope of the application. Inside.

Claims (3)

1. A whitening and freckle-removing cream is characterized in that: comprises the following components in percentage by mass:

9-10% of an antioxidant A; 1-2% of butanediol; erythritol 1-2%; 1-2% of nicotinamide; sodium hyaluronate 0.1-0.3%; carbomer 0.1-0.2%; 0.1 to 0.2 percent of p-hydroxyacetophenone; 3-5% of isononyl isononanoate; jojoba seed oil 1-2%; 1-2% of polydimethylsiloxane; 1-2% of emulsifying agent; 1-3% of squalane; 0.2-0.4% of tocopheryl acetate; 0.2-0.3% of ascorbyl tetraisopalmitate; 0.1-0.2% of 1, 2-hexanediol; arginine 0.15-0.2%; arginine ferulate 0.1-0.3%; 0.6 to 0.8 percent of 1-methyl hydantoin-2-imide; 0.2-0.4% of diglucosyl gallic acid; 4-6% of an antioxidant B; 1-3% of a whitening agent; 0.002-0.003% of Glycyrrhiza glabra root extract; cyclodextrin 0.08-0.10%; the balance being water; the total mass percentage is 100 percent;

wherein the antioxidant A consists of the following components in percentage by mass:

95-98% of fermentation product filtrate of the saccharomyces cerevisiae;

0.6 to 0.7 percent of p-hydroxyacetophenone;

0.5-0.7% of butanediol;

0.6-3.9% of 1, 2-hexanediol;

the whitening agent comprises hydrolyzed European plums, strawberry saxifrage extracts and water, wherein the hydrolyzed European plums and strawberry saxifrage extracts respectively account for 0.3-0.5% of the whitening agent, 0.1-0.2% of the whitening agent, and the balance is water;

the preparation method of the strawberry saxifraga extract comprises the following steps:

weighing strawberry herba Saxifragae, pulverizing into coarse powder, reflux-extracting with 80% ethanol for 2-3 times (1-2 hr each time), filtering, mixing filtrates, recovering ethanol under reduced pressure, concentrating the rest solution, sequentially extracting with petroleum ether and ethyl acetate for 2-3 times (4-5 times) by volume, mixing ethyl acetate extracts, and evaporating under reduced pressure to dryness to obtain strawberry herba Saxifragae extract;

the mass percentage of the strawberry saxifrage extract is 25-30% of erythritol;

the antioxidant B consists of the following components in percentage by mass:

ellagic acid 26-30%;

35-40% of butanediol;

0.1-0.2% of 1, 2-hexanediol;

0.1-0.2% of ethylhexyl glycerol;

30-35% of water;

the emulsifier consists of the following components in percentage by mass:

76-80% of cetostearyl alcohol;

18.5 to 19.6 percent of cetylglucosides;

glucose 0.1-0.3%;

0.7-5.9% of water.

2. The whitening and freckle-removing cream according to claim 1, wherein: the whitening agent is replaced by the following composition, and the composition comprises the following components in percentage by mass:

45-50% of butanediol;

0.4-0.5% of arbutin;

citric acid 0.4-0.6%;

sodium sulfite 0.3-0.5%;

0.1-0.2% of acetyl tyrosine;

0.07-0.09% of peony root extract;

0.04 to 0.06 percent of amino propanol ascorbyl phosphate;

0.03-0.05% of radix scutellariae extract;

glutathione 0.004-0.006%;

hydrolyzing European plums 0.3-0.5%;

0.1-0.2% of strawberry saxifrage extract;

the balance being water.

3. A method for preparing the whitening and freckle-removing cream as claimed in any one of claims 1 to 2, which is characterized in that: the method comprises the following steps:

s1: weighing raw materials including antioxidant A, butanediol, erythritol, nicotinamide, sodium hyaluronate, carbomer, p-hydroxyacetophenone and water according to a formula, sequentially adding into a main pot, stirring and heating to 80-85 ℃, homogenizing to fully dissolve the raw materials to obtain a mixture A;

s2: respectively weighing isononyl isononanoate, jojoba seed oil, polydimethylsiloxane, an emulsifier, squalane, tocopherol acetate and ascorbic acid tetraisopalmitate, sequentially adding into an oil phase pot, heating to 83-85 ℃, pumping into a main pot after complete dissolution, homogenizing for 5-8 minutes, and preserving heat for 30-35 minutes to obtain a mixture B;

s3: then starting to cool to 45-50 ℃, respectively adding raw materials 1, 2-hexanediol and arginine into a main pot, uniformly stirring, and cooling to 40-43 ℃;

s4: adding arginine ferulate, 1-methylhydantoin-2-imide, diglucosyl gallic acid, antioxidant B and whitening agent, stirring, and cooling to 36-38deg.C.