CN115445028A - An automatic injection adjustment system - Google Patents
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- CN115445028A CN115445028A CN202211332175.3A CN202211332175A CN115445028A CN 115445028 A CN115445028 A CN 115445028A CN 202211332175 A CN202211332175 A CN 202211332175A CN 115445028 A CN115445028 A CN 115445028A
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- 238000002347 injection Methods 0.000 title claims abstract description 54
- 239000007924 injection Substances 0.000 title claims abstract description 54
- 239000007788 liquid Substances 0.000 claims abstract description 48
- 238000000520 microinjection Methods 0.000 claims abstract description 23
- 230000001105 regulatory effect Effects 0.000 claims abstract description 16
- 230000001276 controlling effect Effects 0.000 claims 1
- -1 double-plate bracket Substances 0.000 claims 1
- 230000036772 blood pressure Effects 0.000 description 9
- 239000003814 drug Substances 0.000 description 9
- 229940079593 drug Drugs 0.000 description 3
- 238000000034 method Methods 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 238000001523 electrospinning Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000004949 mass spectrometry Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000001690 micro-dialysis Methods 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2051—Connecting means having tap means, e.g. tap means activated by sliding
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/36—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests with means for eliminating or preventing injection or infusion of air into body
- A61M5/365—Air detectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2006—Having specific accessories
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3334—Measuring or controlling the flow rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/30—Blood pressure
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Abstract
本发明提供了一种自动针剂调节系统,包括:面板;第一微量注射泵、第二微量注射泵,安装在面板上,通过电机的带动来注入和输出液体;液体存储装置,安装在面板上,用于存储注射所需的液体;第一流量传感器、第二流量传感器,安装在面板上,用于检测液体的流量;第一压力传感器、第二压力传感器,安装在面板上,用于检测液体的压力;第一气泡传感器、第二气泡传感器,安装在面板上,用于检测液体的气泡含量;第一流量调节阀、第二流量调节阀,安装在面板上,用于调节液体的实时流量;功控屏,安装在面板上,用于观察各传感器,反馈回来的参数,并及时的发出修正信号;第一液体输出管路、第二输出管路,使用传感器固定,用于输出液体;第一注射区、第二注射区,受体的液体注入区。
The invention provides an automatic injection adjustment system, comprising: a panel; a first micro-injection pump and a second micro-injection pump installed on the panel to inject and output liquid driven by a motor; a liquid storage device installed on the panel , used to store the liquid required for injection; the first flow sensor and the second flow sensor are installed on the panel to detect the flow of the liquid; the first pressure sensor and the second pressure sensor are installed on the panel to detect The pressure of the liquid; the first air bubble sensor and the second air bubble sensor are installed on the panel to detect the bubble content of the liquid; the first flow regulating valve and the second flow regulating valve are installed on the panel to adjust the real-time flow of the liquid Flow rate; power control panel, installed on the panel, used to observe the parameters fed back by each sensor, and send a correction signal in time; the first liquid output pipeline and the second output pipeline, fixed by sensors, are used to output liquid ; The first injection area, the second injection area, the liquid injection area of the receptor.
Description
技术领域technical field
本发明涉及医疗器械技术领域, 尤其涉及一种自动针剂调节系统。The invention relates to the technical field of medical devices, in particular to an automatic injection adjustment system.
背景技术Background technique
随着临床医学精确给药、微流芯片、药物/营养学研究、微透析、反应堆定量给药、生物反应器、细胞注射、静电纺丝、质谱分析等要求越来越严格,传统注射方式已不能满足人们的需要,精度较高的微量注射泵由此产生。With the increasingly stringent requirements for precise drug delivery in clinical medicine, microfluidic chips, drug/nutrition research, microdialysis, reactor dosing, bioreactors, cell injection, electrospinning, mass spectrometry, etc., traditional injection methods have become increasingly strict. Can not meet people's needs, resulting in a higher precision micro-injection pump.
但常见的微型注射泵,所输出的药剂量只是电脑上给出的固定数值,而没有进行输出后的数值测量,如《一种微量注射泵》202010339772 .3中,只是通过电机带动丝杠螺母,驱动注射器注射一定的药剂,以及采用超声换能器来测量液体的输出量,精确度并不高。However, the output of the common micro-injection pump is only a fixed value given by the computer, and there is no measurement of the output value. For example, in "A Micro-injection Pump" 202010339772.3, the screw nut is only driven by the motor , driving the syringe to inject a certain medicament, and using an ultrasonic transducer to measure the output of the liquid, the accuracy is not high.
对于现有的微量注射泵而言,流速及稳定精度是影响注射泵品质的一个重要因素,而现有技术一般集中在提高注射泵的电机的最小进给距离上,通过新型微步步进电机及控制软件提供最低的流速。不仅忽略了给进液体与腔体之间、以及柱塞与腔体之间的摩擦力由静摩擦到动摩擦之间转换导致摩擦系数的改变,也即柱塞和液体在由静至动的瞬间与腔体之间的摩擦力会发生变化,导致注射出现超调、过量等问题,影响柱塞的进给精度;而且忽略了进入注射器的液体是否存在气泡的因素。For the existing micro-injection pumps, the flow rate and stable accuracy are an important factor affecting the quality of the injection pump, while the existing technology generally focuses on improving the minimum feed distance of the motor of the injection pump, through the new micro-stepping motor and control software to provide the lowest flow rate. Not only ignores the change of the friction coefficient between the feed liquid and the cavity, and the friction between the plunger and the cavity from static friction to dynamic friction, that is, the plunger and the liquid at the moment from static to dynamic The friction between the cavities will change, leading to problems such as overshoot and overshoot in the injection, which will affect the feeding accuracy of the plunger; and the factor of whether there are bubbles in the liquid entering the syringe is ignored.
综合上述现有微型注射泵存在问题,发明了一种自动针剂调节系统。Based on the problems existing in the existing miniature syringe pumps above, an automatic injection adjustment system has been invented.
发明内容Contents of the invention
本发明的目的在于提供一种精确的药剂流量、流速、气泡及压力变化,能够提高药物摄入的准确性。The purpose of the present invention is to provide a precise medicament flow, flow velocity, bubble and pressure change, which can improve the accuracy of medicament intake.
为实现上述目的,本发明中的微量注射泵采用如下技术方案:In order to achieve the above object, the micro-injection pump in the present invention adopts the following technical scheme:
一种自动针剂调节系统,其组成包括面板;流量传感器、流量调节阀、压力传感器及气泡传感器包括面板10,面板10以左右划分两部分,左部为功控屏,右部为液体存储装置;面板10以上下划分为两部分,上部为第一自动针剂调节系统,下部为第二自动针剂调节系统。An automatic injection adjustment system, which consists of a panel; a flow sensor, a flow regulating valve, a pressure sensor and an air bubble sensor include a
所述第一针剂调节系统与第二针剂调节系统布局一致,本发明只对第一针剂调节系统进行介绍;The layout of the first injection adjustment system is consistent with that of the second injection adjustment system, and the present invention only introduces the first injection adjustment system;
所述第一针剂调节系统,包括微量注射泵2,微量注射泵2由直流电机2014驱动丝杠2016带动移动挡板2012前进、后退,从而带动注射针管2019进行药剂的吸入和输出;所述注射针管2019固定端放置于双板支架2011上,用夹紧夹2018进行前端夹紧固定;所述注射针管2019移动端固定于移动挡板2012上,用微型挡板2017进行固定;所述支撑柱2015贯穿于双板支架2011、移动挡板2012并连接到直流电机2014上,起到支撑作用;所述基底2013用于固定双板支架2011和直流电机2014,起到定位支撑作用;The first injection adjustment system includes a micro-injection pump 2, and the micro-injection pump 2 is driven by a
所述第一微量注射泵201通过底座2013用螺栓固定于面板10上。The first
所述储液槽102中的液体通过直流电机2014的带动后经过Y型管901、T型管902的分流吸入注射针管2019内部,所述注射针管2019通过直流电机带动丝杠2016使得注射针管2019内部的液体T型管902按照一定的速度流出;The liquid in the
所述经T型管902流出的液体先后流经第一流量传感器301、第一血压传感器401、第一气泡传感器501及第一流量调节阀601;所述第一流量传感器301、第一血压传感器401、第一气泡传感器501及第一流量调节阀601连接功控屏7,通过功控屏7来判断液体的流量、流速及气泡,从而达到对所述第一输出管道904中液体的控制,以符合所需的要求。The liquid flowing out of the T-
所述第一流量传感器301、第一血压传感器401、第一气泡传感器501及第一流量调节阀601通过固定槽位分别用螺栓固定于面板10上。The
传感器部分包括:流量传感器、流量调节阀、压力传感器、气泡传感器设置在面板上,用于检测液体状态;The sensor part includes: flow sensor, flow regulating valve, pressure sensor, and air bubble sensor are set on the panel to detect the state of the liquid;
液体存储装置包括:箱体和保护罩,安装在面板上,用于存放所需的液体;The liquid storage device includes: a box body and a protective cover, which are installed on the panel and used to store the required liquid;
功控屏,安装在面板上,用于读取参数;Power control screen, installed on the panel, used to read parameters;
安装结构,设置在面板上,用于安装传感器、液体存储装置、功控屏、管路微量注射泵;The installation structure is arranged on the panel, and is used for installing sensors, liquid storage devices, power control panels, and pipeline micro-injection pumps;
微量注射泵包括:针管、针管固定装置、丝杠、基座、支撑柱及电机;The micro injection pump includes: needle tube, needle tube fixing device, lead screw, base, support column and motor;
针管的固定端放在针管固定装的双板支架上,用夹紧夹夹紧防止转动,双板支架固定在基座的左端;移动端安装在与丝杠相连的针管固定装置上,用挡板夹紧移动端,保证丝杠能与针管移动端实时移动;The fixed end of the needle tube is placed on the double-plate bracket of the needle tube fixing device, and is clamped with a clamp to prevent rotation. The double-plate bracket is fixed on the left end of the base; The plate clamps the moving end to ensure that the screw can move in real time with the moving end of the needle tube;
丝杠左端放置在双板支架上,右端通过安装板与电机相连,安装板固定在基座的右端The left end of the screw is placed on the double-plate bracket, the right end is connected to the motor through the mounting plate, and the mounting plate is fixed on the right end of the base
支撑柱贯穿双板支架与安装板,用于支撑整体的结构。The support column runs through the double-plate support and the mounting plate, and is used to support the overall structure.
进一步的,为了我们能更直观的得到各传感器的参数对比,在面板上设置了功控屏,通过功控屏调整参数来控制液体的压力、流量参数;Furthermore, in order for us to obtain the comparison of the parameters of each sensor more intuitively, a power control screen is set on the panel, and the parameters of the power control screen are adjusted to control the pressure and flow parameters of the liquid;
进一步的,为了能够达到不同的液体速度,流量条件,为此在面板上设置了两套这样的系统。Further, in order to achieve different liquid velocity and flow conditions, two sets of such systems are set on the panel.
上述技术方案的有益效果在于:原本的微量注射泵不足以达到可直接注入人体的条件,在设置了流量传感器、流量调节阀、压力传感器后液体的流量、压力得到了较好的控制,可以达到注入人体的标准;在设置了气泡传感后液体中的气泡得到了较好的控制,可以达到注入人体的标准;这样设置的自动针剂调节系统不仅可以用于自动的药物配比,而且可以直接把药物注入人体。The beneficial effect of the above technical solution is that the original micro-injection pump is not enough to meet the conditions of direct injection into the human body. After the flow sensor, flow regulating valve, and pressure sensor are installed, the flow and pressure of the liquid are better controlled, which can achieve The standard for injecting into the human body; after setting the bubble sensor, the air bubbles in the liquid are well controlled, which can reach the standard for injecting into the human body; the automatic injection adjustment system set in this way can not only be used for automatic drug proportioning, but also can be used directly Inject the drug into the body.
附图说明Description of drawings
图1为本发明结构示意图Fig. 1 is a structural representation of the present invention
图2为本发明主视图Fig. 2 is the front view of the present invention
图3为本发明左视图Fig. 3 is the left view of the present invention
图4为本发明中微量注射泵结构示意图Fig. 4 is the structure schematic diagram of micro-injection pump in the present invention
图5为本发明中微量注射泵俯视图Figure 5 is a top view of the micro-injection pump in the present invention
图中标号:1、液体存储装置;101、保护罩;102、储液槽;2、微量注射泵;201、第一微量注射泵;2011、双板支架;2012、移动挡板;2013、基底;2014、直流电机;2015、支撑柱;2016、丝杠;2017、微型挡板;2018、夹紧夹;2019、注射针管;202、第二微量注射泵(因其两个注射泵相同这里只对第一个微量注射泵进行介绍);3、流量传感器;301、第一流流量传感器;302、第二流量传感器;4、血压传感器;401、第一血压传感器;402、第二血压传感器;5、气泡传感器;501、第一气泡传感器;502、第二气泡传感器;6、流量调节阀;601第一流量调节阀;602、第二流量调节阀;7、功控屏;8、注射区;801、第一注射区;802、第二注射区;9、管路布局;901、Y型管路;902、第一T型管路;903、第二T型管路;904;第一液体输出管路;905、第二液体输出管路;10、面板。Reference numerals in the figure: 1, liquid storage device; 101, protective cover; 102, liquid storage tank; 2, micro-injection pump; 201, first micro-injection pump; 2011, double-plate support; 2012, mobile baffle; 2013, base ; 2014, DC motor; 2015, supporting column; 2016, lead screw; 2017, micro baffle; 2018, clamping clip; 2019, injection needle tube; 3. Flow sensor; 301. First flow sensor; 302. Second flow sensor; 4. Blood pressure sensor; 401. First blood pressure sensor; 402. Second blood pressure sensor; 5 , air bubble sensor; 501, first air bubble sensor; 502, second air bubble sensor; 6, flow regulating valve; 601 first flow regulating valve; 602, second flow regulating valve; 7, power control screen; 8, injection area; 801. First injection area; 802. Second injection area; 9. Pipeline layout; 901. Y-shaped pipeline; 902. First T-shaped pipeline; 903. Second T-shaped pipeline; 904; First liquid Output pipeline; 905, second liquid output pipeline; 10, panel.
具体实施方式detailed description
以下结合实施例对本发明的特征和性能作进一步的详细描述。The characteristics and performance of the present invention will be described in further detail below in conjunction with the examples.
实施例1:如图1-5所示,一种自动针剂调节系统,包括面板10,面板10以左右划分两部分,左部为功控屏,右部为液体存储装置;面板10以上下划分为两部分,上部为第一自动针剂调节系统,下部为第二自动针剂调节系统。Embodiment 1: As shown in Figure 1-5, an automatic injection adjustment system includes a
所述第一针剂调节系统与第二针剂调节系统布局一致,本发明只对第一针剂调节系统进行介绍;The layout of the first injection adjustment system is consistent with that of the second injection adjustment system, and the present invention only introduces the first injection adjustment system;
所述第一针剂调节系统,包括微量注射泵2,微量注射泵2由直流电机2014驱动丝杠2016带动移动挡板2012前进、后退,从而带动注射针管2019进行药剂的吸入和输出;所述注射针管2019固定端放置于双板支架2011上,用夹紧夹2018进行前端夹紧固定;所述注射针管2019移动端固定于移动挡板2012上,用微型挡板2017进行固定;所述支撑柱2015贯穿于双板支架2011、移动挡板2012并连接到直流电机2014上,起到支撑作用;所述基底2013用于固定双板支架2011和直流电机2014,起到定位支撑作用;The first injection adjustment system includes a micro-injection pump 2, and the micro-injection pump 2 is driven by a
所述第一微量注射泵201通过底座2013用螺栓固定于面板10上。The first
所述储液槽102中的液体通过直流电机2014的带动后经过Y型管901、T型管902的分流吸入注射针管2019内部,所述注射针管2019通过直流电机带动丝杠2016使得注射针管2019内部的液体T型管902按照一定的速度流出;The liquid in the
所述经T型管902流出的液体先后流经第一流量传感器301、第一血压传感器401、第一气泡传感器501及第一流量调节阀601;所述第一流量传感器301、第一血压传感器401、第一气泡传感器501及第一流量调节阀601连接功控屏7,通过功控屏7来判断液体的流量、流速及气泡,从而达到对所述第一输出管道904中液体的控制,以符合所需的要求。The liquid flowing out of the T-
所述第一流量传感器301、第一血压传感器401、第一气泡传感器501及第一流量调节阀601通过固定槽位分别用螺栓固定于面板10上。The
以上所述,仅为本发明的较佳实施例,并不用以限制本发明,本发明的专利保护范围以权利要求书为准,凡是运用本发明的说明书及附图内容所作的等同结构变化,同理均应包含在本发明的保护范围内。The above is only a preferred embodiment of the present invention, and is not intended to limit the present invention. The scope of patent protection of the present invention is subject to the claims. Any equivalent structural changes made by using the description and accompanying drawings of the present invention, All should be included in the protection scope of the present invention in the same way.
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Application publication date: 20221209 |