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CN115089342B - Endoleak measurement device for a fenestrated stent graft and working method thereof - Google Patents

Endoleak measurement device for a fenestrated stent graft and working method thereof

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Publication number
CN115089342B
CN115089342B CN202210856062.7A CN202210856062A CN115089342B CN 115089342 B CN115089342 B CN 115089342B CN 202210856062 A CN202210856062 A CN 202210856062A CN 115089342 B CN115089342 B CN 115089342B
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internal leakage
branch
vitro
main
stent
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CN115089342A (en
Inventor
李栋林
贺元
张鸿坤
李振江
祝茜茜
王晓辉
邱宸阳
汪洵
陈天驰
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First Affiliated Hospital of Zhejiang University School of Medicine
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First Affiliated Hospital of Zhejiang University School of Medicine
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01M—TESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M3/00—Investigating fluid-tightness of structures
    • G01M3/02—Investigating fluid-tightness of structures by using fluid or vacuum
    • G01M3/04—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

The invention belongs to the technical field of medical appliances, in particular to an internal leakage measuring device of a windowed covered stent and a working method thereof, which comprises an external bifurcation type analog vascular system and an external constant pressure perfusion system connected to the external bifurcation type analog vascular system, the in-vitro bifurcation type simulated vascular system comprises a main pipeline, a plurality of branch pipelines connected to the main pipeline, a main pipeline support arranged in the main pipeline, and at least one branch pipeline support arranged in one of the branch pipelines, wherein an internal leakage collecting pipe is prefabricated at the starting position of the branch pipeline. When the internal leakage measurement is carried out, only the circulating liquid flowing out in the internal leakage collecting pipe is required to be collected, the internal leakage quantity is directly obtained, the internal leakage condition between the main pipeline support and the branch pipeline support after windowing is analyzed, the internal leakage rate of the branch pipeline support is calculated, the system structure is simple, the use is simple and convenient, and the measurement result is visual, stable and reliable.

Description

Inner leakage measuring device of windowed type tectorial membrane bracket and working method thereof
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to an internal leakage measuring device of a windowed type tectorial membrane bracket and a working method thereof.
Background
In the endoluminal treatment of aortic arch lesions (aortic dissection B and aortic arch aneurysm), a thoracic aortic stent graft is typically applied to completely cover the arch lesion. And the aortic arch part sends out three important branch vessels on the arch to supply blood to the upper limbs and the front and back circulation of the brain respectively. For aortic arch lesions that involve important branches, it is necessary to reconstruct the branch arteries above the arch while the main stent of the thoracic aortic body covers the arch lesions. The reconstruction mode of the branch artery on the arch comprises pre-windowing, in-situ windowing and reconstruction by using a modularized branch bracket. Currently, a windowing technology is more adopted. Namely, on the main body stent of the thoracic aorta, a window is opened on the covered stent by means of needling or radio frequency ablation, laser cauterization and the like at the position of the opening of the branch artery on the arch, and the branch stent of the branch artery is placed through the window, so that the blood flow to the upper limbs and the brain is reserved. However, since the main stent body of the stent graft does not have a window, good matching between the main stent body and the branch stent body cannot be ensured after the window is opened by the physical method, and blood flow is easy to leak from the edge of the window and the edge of the branch stent, so that internal leakage is formed. The large internal leakage can cause incomplete isolation of the covered stent to aortic arch lesions, and even poor long-term effect of operation and further development of diseases. Therefore, how to effectively evaluate the endoleak degree of the windowed stent has important clinical significance.
Disclosure of Invention
The invention aims to solve the technical problem of how to detect the internal leakage degree between a windowed aortic tectorial membrane bracket and a branch bracket, and provides an internal leakage measuring device of the windowed aortic tectorial membrane bracket, which only needs to collect circulating liquid flowing out of an internal leakage collecting pipe, directly obtains the internal leakage liquid quantity, calculates and analyzes the internal leakage rate between a main pipeline bracket and a branch pipeline bracket after windowing, has simple structure, is convenient to use, and has visual, stable and reliable measuring results, and a working method thereof.
The technical scheme of the invention is that the internal leakage measuring device of the windowed tectorial membrane bracket comprises an external bifurcation type analog vascular system and an external constant pressure perfusion system connected to the external bifurcation type analog vascular system, wherein the external bifurcation type analog vascular system comprises a main pipeline, a plurality of branch pipelines connected to the main pipeline, a main pipeline bracket arranged in the main pipeline and at least one branch pipeline bracket arranged in one of the branch pipelines, and an internal leakage collecting pipe is prefabricated at the starting position of the branch pipeline.
Preferably, a hemispherical opening is arranged at the starting position of the branch pipeline, and the internal leakage liquid collecting pipe is prefabricated on the hemispherical opening.
Preferably, the inner diameter of the main body pipeline is 34mm, the inner diameter of the branch pipeline is 10mm, the inner diameter of the inner leakage collecting pipe is 2mm, and the main body pipeline, the branch pipeline and the inner leakage collecting pipe are made of silica gel or elastomer.
Preferably, the extracorporeal constant pressure perfusion system comprises a circulating fluid tank, a simulated blood vessel fixing interface for connecting a main body pipeline, and a constant pressure motor system for driving circulating fluid to flow in an extracorporeal bifurcation type simulated blood vessel system.
Preferably, the simulated blood vessel fixing interface is connected with one end of the main body pipeline through the circulating liquid conveying pipe, and the other end of the main body pipeline is plugged through a first sealing rubber plug.
Preferably, the number of the branch pipes is three, the three branch pipes are equidistantly connected to the same side of the main body pipe, and the end, far away from the main body pipe, of each branch pipe is plugged by a second sealing rubber plug.
Preferably, the main body pipeline bracket is a fenestrated aortic stent-graft bracket, which is divided into a single fenestrated aortic stent-graft bracket, a double fenestrated aortic stent-graft bracket and a triple fenestrated aortic stent-graft bracket, and the branch pipeline bracket is a branched arterial stent-graft bracket.
The working method of the internal leakage measuring device of the windowed type tectorial membrane bracket comprises the following steps:
1) Firstly, removing residual air in the whole in-vitro bifurcation type analog vascular system and the in-vitro constant pressure perfusion system;
2) Starting an in-vitro constant pressure perfusion system, operating the system under the pressure environment of 80-160mmHg at 1.2Hz, and driving circulating liquid to flow in an in-vitro bifurcation type simulated vascular system by a constant pressure motor system;
3) Through collecting the circulating liquid that flows out in the internal leakage collecting pipe of lateral conduit initial position department, directly obtain internal leakage liquid volume, the internal leakage condition between main body pipeline support and the lateral conduit support after the analysis aassessment windowing calculates the internal leakage rate of lateral conduit support.
When the internal leakage measurement is carried out, only the circulating liquid flowing out in the internal leakage collecting pipe is required to be collected, the internal leakage quantity is directly obtained, the internal leakage condition between the main pipeline support and the branch pipeline support after windowing is analyzed, the internal leakage rate of the branch pipeline support is calculated, the system structure is simple, the use is simple and convenient, and the measurement result is visual, stable and reliable.
Drawings
FIG. 1 is a schematic structural diagram of embodiment 1 of the present invention;
FIG. 2 is a schematic diagram of an in vitro bifurcation type analog vascular system in example 1 of the present invention;
FIG. 3 is a schematic structural diagram of embodiment 2 of the present invention;
FIG. 4 is a schematic diagram showing the structure of an in vitro bifurcation type analog vascular system in example 2 of the present invention;
FIG. 5 is a schematic structural diagram of embodiment 3 of the present invention;
FIG. 6 is a schematic diagram showing the structure of an in vitro bifurcation type analog vascular system in example 3 of the present invention;
FIG. 7 is a schematic diagram of the structure of the various tubes of the in vitro bifurcated analog vascular system of the present invention;
In the figure, a main pipeline, a branch pipeline, an internal leakage collecting pipe, a main pipeline bracket, a branch pipeline bracket, a hemispherical opening, an external constant pressure pouring system, a circulating liquid conveying pipe, a first sealing rubber plug, a second sealing rubber plug and a third sealing rubber plug are shown in the figure, wherein the main pipeline, the branch pipeline, the internal leakage collecting pipe, the main pipeline bracket, the branch pipeline bracket, the hemispherical opening and the circulating liquid conveying pipe are shown in the figure, and the external constant pressure pouring system is shown in the figure.
Detailed Description
The invention will now be described in further detail with reference to the drawings and examples, which are not intended to limit the scope of the invention.
Example 1
As shown in fig. 1,2 and 7, an endoleak measuring device of a fenestration type stent graft includes an in vitro bifurcation type artificial vascular system and an in vitro constant pressure perfusion system 7 connected to the in vitro bifurcation type artificial vascular system, the in vitro bifurcation type artificial vascular system includes a main body tube 1 and three branch tubes 2 connected to the main body tube 1, and a main body tube support 4 installed in the main body tube 1 and a branch tube support 5 installed in one of the branch tubes 2, and an endoleak collecting tube 3 is prefabricated at a start position of the branch tube 2. The starting position of the branch pipe 2 is provided with a hemispherical opening 6, and the inner leakage collecting pipe 3 is prefabricated on the hemispherical opening 6. The inner diameter of the main pipeline 1 is 34mm, the inner diameter of the branch pipeline 2 is 10mm, the inner diameter of the inner leakage collecting pipe 3 is 2mm, and the main pipeline 1, the branch pipeline 2 and the inner leakage collecting pipe 3 are made of silica gel or elastomer. The extracorporeal constant pressure perfusion system 7 comprises a circulating fluid tank, a simulated blood vessel fixing interface for connecting a main body pipeline, and a constant pressure motor system for driving circulating fluid to flow in an extracorporeal bifurcation type simulated blood vessel system. The simulated blood vessel fixing interface is connected with one end of the main pipeline 1 through a circulating liquid conveying pipe 8, and the other end of the main pipeline 1 is plugged by a first sealing rubber plug 9. The three branch pipelines are equidistantly connected to the same side of the main pipeline 1, and the end, far away from the main pipeline, of each branch pipeline is plugged by a second sealing rubber plug 10. The main body pipeline bracket 4 is a single-open window type aortic tectorial membrane bracket, and the branch pipeline bracket 5 is a branch arterial tectorial membrane bracket.
Example 2
As shown in fig. 3, 4 and 7, the in vitro bifurcation type simulated vascular system comprises a main body duct 1, three branch ducts 2 connected to the main body duct 1, a main body duct support 4 installed in the main body duct 1, and two branch duct supports 5 installed in two of the branch ducts 2, respectively, the main body duct support 4 is a double-windowed aortic stent-graft support, and the branch duct supports 5 are branched arterial stent-grafts.
Example 3
As shown in fig. 5 to 7, the in vitro bifurcation type simulated vascular system comprises a main body duct 1, three branch ducts 2 connected to the main body duct 1, a main body duct support 4 installed in the main body duct 1, and three branch duct supports 5 installed in the three branch ducts 2 respectively, wherein the main body duct support 4 is a three-window type aortic stent graft, and the branch duct supports 5 are branch arterial stent grafts.
The working method of the internal leakage measuring device of the windowed type tectorial membrane bracket comprises the following steps:
1) Firstly, removing residual air in the whole in-vitro bifurcation type analog vascular system and the in-vitro constant pressure perfusion system;
2) Starting an in-vitro constant pressure perfusion system, operating the system under the pressure environment of 80-160mmHg at 1.2Hz, and driving circulating liquid to flow in an in-vitro bifurcation type simulated vascular system by a constant pressure motor system;
3) Through collecting the circulating liquid that flows in the internal leakage collecting pipe of lateral conduit initial position department, directly obtain internal leakage liquid volume, the internal leakage condition between main body pipeline support and the lateral conduit support after the analysis aassessment windowing calculates the internal leakage rate of lateral conduit support.
The external constant pressure perfusion system is conventional equipment purchased in the market, and the specific structure and the working process are conventional means, so that details are not described.
When the internal leakage measurement is carried out, the circulating liquid is filled into the blood vessel simulation system by the external bifurcation type simulated blood vessel system, the circulating liquid is driven by the constant voltage motor system to fill the circulating liquid into the blood vessel simulation system at constant pressure, after a certain time, the circulating liquid flowing out of the internal leakage liquid collecting pipe on the side wall of the simulated branch blood vessel is collected, the internal leakage liquid quantity is directly obtained, the internal leakage condition between the main pipeline support and the branch pipeline support after windowing is analyzed, the internal leakage rate of the branch pipeline support after windowing is calculated, the structure is simple, the use is simple and convenient, and the measurement result is visual, stable and reliable.

Claims (5)

1.一种开窗型覆膜支架的内漏测量装置，其特征在于：其包括体外分叉型模拟血管系统和连接在体外分叉型模拟血管系统上的体外恒压灌注系统，所述体外分叉型模拟血管系统包括一个主体管道和若干个连接在主体管道上的分支管道以及1个安装在主体管道内的主体管道支架和至少一个安装在其中一个分支管道内的分支管道支架，所述分支管道的起始位置上预制有内漏液收集管；1. A device for measuring endoleakage of a fenestrated stent graft, comprising an in vitro bifurcated simulated vascular system and an in vitro constant-pressure perfusion system connected to the bifurcated simulated vascular system. The in vitro bifurcated simulated vascular system comprises a main conduit and several branch conduits connected to the main conduit, a main conduit support mounted within the main conduit, and at least one branch conduit support mounted within one of the branch conduits. An endoleakage collection tube is prefabricated at the starting position of each branch conduit. 所述分支管道的起始位置上设有半球形开口，所述内漏液收集管预制在半球形开口上；A hemispherical opening is provided at the starting position of the branch pipe, and the internal leakage liquid collection pipe is prefabricated on the hemispherical opening; 所述体外恒压灌注系统包括循环液箱、用于连接主体管道的模拟血管固定接口、用于驱动循环液在体外分叉型模拟血管系统中流动的恒压电机系统；The in vitro constant pressure perfusion system includes a circulating fluid tank, a simulated blood vessel fixing interface for connecting to a main body pipeline, and a constant pressure motor system for driving the circulating fluid to flow in the in vitro bifurcated simulated blood vessel system; 该开窗型覆膜支架的内漏测量装置的工作方法，步骤如下：The working method of the endoleak measurement device of the fenestrated stent graft comprises the following steps: 1）先排除整个体外分叉型模拟血管系统与体外恒压灌注系统里残留的空气；1) First, remove the air remaining in the entire in vitro bifurcated simulated vascular system and the in vitro constant pressure perfusion system; 2）开启体外恒压灌注系统，在1.2Hz，压力环境为80-160mmHg下运行系统，由恒压电机系统驱动循环液在体外分叉型模拟血管系统内流动；2) Start the in vitro constant pressure perfusion system and operate it at 1.2 Hz and a pressure environment of 80-160 mmHg. The constant pressure motor system drives the circulating fluid to flow in the in vitro bifurcated simulated vascular system. 3）通过收集分支管道起始位置处内漏液收集管中流出的循环液，直接获得内漏液体量，分析评估开窗后主体管道支架和分支管道支架之间的内漏情况，计算得出分支管道支架的内漏率。3) By collecting the circulating fluid flowing out of the internal leakage collection tube at the starting position of the branch pipe, the internal leakage amount is directly obtained. The internal leakage between the main pipe support and the branch pipe support after the window is opened is analyzed and evaluated, and the internal leakage rate of the branch pipe support is calculated. 2.根据权利要求1所述的一种开窗型覆膜支架的内漏测量装置，其特征在于：所述主体管道的内径为34mm，所述分支管道的内径为10mm，所述内漏液收集管的内径为2mm，所述主体管道、分支管道和内漏液收集管的材料为人造橡胶。2. The internal leakage measuring device of a window-type coated stent according to claim 1 is characterized in that: the inner diameter of the main pipe is 34 mm, the inner diameter of the branch pipe is 10 mm, the inner diameter of the internal leakage liquid collection tube is 2 mm, and the material of the main pipe, branch pipe and internal leakage liquid collection tube is artificial rubber. 3.根据权利要求1所述的一种开窗型覆膜支架的内漏测量装置，其特征在于：所述模拟血管固定接口通过循环液输送管与主体管道的一端连接，所述主体管道的另一端通过一号密封橡胶塞封堵。3. The internal leakage measurement device of a window-type covered stent according to claim 1 is characterized in that the simulated blood vessel fixed interface is connected to one end of the main pipeline through a circulating fluid delivery tube, and the other end of the main pipeline is sealed by a No. 1 sealing rubber plug. 4.根据权利要求1所述的一种开窗型覆膜支架的内漏测量装置，其特征在于：所述分支管道的数量为三个，三个分支管道等距连接在主体管道的同一侧，且每个分支管道的远离主体管道端均通过二号密封橡胶塞封堵。4. The internal leakage measuring device of a window-type coated stent according to claim 1 is characterized in that: the number of the branch pipes is three, the three branch pipes are equidistantly connected to the same side of the main pipe, and the end of each branch pipe away from the main pipe is sealed by a No. 2 sealing rubber plug. 5.根据权利要求1所述的一种开窗型覆膜支架的内漏测量装置，其特征在于：所述主体管道支架为开窗型主动脉覆膜支架，其分为单开窗型主动脉覆膜支架、双开窗型主动脉覆膜支架、三开窗型主动脉覆膜支架三种，所述分支管道支架为分支动脉覆膜支架。5. An internal leakage measurement device for a fenestrated covered stent according to claim 1, characterized in that: the main pipe stent is a fenestrated aortic covered stent, which is divided into three types: single-fenestrated aortic covered stent, double-fenestrated aortic covered stent, and triple-fenestrated aortic covered stent, and the branch pipe stent is a branch artery covered stent.
CN202210856062.7A 2022-07-08 2022-07-08 Endoleak measurement device for a fenestrated stent graft and working method thereof Active CN115089342B (en)

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JP2015064487A (en) * 2013-09-25 2015-04-09 国立大学法人広島大学 Simulation system, and simulation method of installing stent graft
CN113035036A (en) * 2019-12-09 2021-06-25 深圳市先健畅通医疗有限公司 Blood vessel simulation device
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JP6734194B2 (en) * 2014-01-10 2020-08-05 ボルケーノ コーポレイション Detection of endoleaks associated with aneurysm repair
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Publication number Priority date Publication date Assignee Title
JP2015064487A (en) * 2013-09-25 2015-04-09 国立大学法人広島大学 Simulation system, and simulation method of installing stent graft
CN113035036A (en) * 2019-12-09 2021-06-25 深圳市先健畅通医疗有限公司 Blood vessel simulation device
CN215832946U (en) * 2021-07-27 2022-02-15 福建帝视信息科技有限公司 Vertical pipeline interface weeping detection device
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