CN115067886A - Photoacoustic scanning imaging compensation method, photoacoustic scanning imaging compensation method and photoacoustic scanning imaging compensation system based on voice coil motor - Google Patents
Photoacoustic scanning imaging compensation method, photoacoustic scanning imaging compensation method and photoacoustic scanning imaging compensation system based on voice coil motor Download PDFInfo
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Abstract
本发明属于光声扫描成像技术领域,具体涉及一种基于音圈电机的光声扫描成像补偿方法、成像方法及系统。光声扫描成像补偿方法,包括:判断各实际出光位置与相应设定出光位置的偏差值是否均满足要求;若否,则根据各实际出光位置对各设定出光位置进行补偿,获得各补偿出光位置,将各补偿出光位置作为下次运动的各设定出光位置,执行步骤S2;若是,则将该次运动的各设定出光位置作为满足需求的各设定出光位置输出。可以通过预规划补偿的运动控制实现高速状态下的等间距输出,实现高速,高分辨率,无失真的成像功能。
The invention belongs to the technical field of photoacoustic scanning imaging, and particularly relates to a photoacoustic scanning imaging compensation method, imaging method and system based on a voice coil motor. The photoacoustic scanning imaging compensation method includes: judging whether the deviation value of each actual light-emitting position and the corresponding set light-emitting position meets the requirements; if not, compensating each set light-emitting position according to each actual light-emitting position, and obtaining each compensated light-emitting position position, take each compensated light-emitting position as each set light-emitting position of the next movement, and execute step S2; It can realize the equidistant output at high speed through the motion control of pre-planning compensation, and realize the imaging function of high speed, high resolution and no distortion.
Description
技术领域technical field
本发明属于光声扫描成像技术领域,具体涉及一种基于音圈电机的光声扫描成像补偿方法、成像方法及系统。The invention belongs to the technical field of photoacoustic scanning imaging, and in particular relates to a photoacoustic scanning imaging compensation method, imaging method and system based on a voice coil motor.
背景技术Background technique
光声成像(Photoacoustic Imaging,PAI)是近年来发展起来的一种非入侵式和非电离式的新型生物医学成像方法。其中光学分辨率模式依托激光光斑和运动机构有极高的分辨率,可达到1~3μm甚至亚微米级别。Photoacoustic Imaging (PAI) is a new non-invasive and non-ionizing biomedical imaging method developed in recent years. Among them, the optical resolution mode relies on the laser spot and motion mechanism to have extremely high resolution, which can reach 1-3 μm or even sub-micron level.
但因其成像分辨率尤其是CSCAN成像分辨率需要依靠运动机构及信号触发机制,同时由于光学分辨率模式需要达到声学和光学共焦,这导致使用传统步进或者普通直线电机作为制动器的扫描速度过慢,而只运动光斑又无法达到声学和光学共焦条件,易产生畸变,导致数据失真。同时基于实时位置的高速PSO功能的控制器价格高昂,且驱动音圈电机有一定困难,而且信号控制和激光器出光都有微秒级别的延时,运动速度达到一定程度就会产生图像畸变。However, because of its imaging resolution, especially CSCAN imaging resolution, it needs to rely on the motion mechanism and signal trigger mechanism, and because the optical resolution mode needs to achieve acoustic and optical confocality, which leads to the use of traditional stepping or ordinary linear motors as the scanning speed of the brake. Too slow, and only moving the spot can not reach the acoustic and optical confocal conditions, easy to produce distortion, resulting in data distortion. At the same time, the controller with high-speed PSO function based on real-time position is expensive, and it is difficult to drive the voice coil motor, and the signal control and laser output have microsecond-level delay, and image distortion will occur when the movement speed reaches a certain level.
发明内容SUMMARY OF THE INVENTION
本发明的目的是提供一种基于音圈电机的光声扫描成像补偿方法及系统、成像方法及系统。The purpose of the present invention is to provide a photoacoustic scanning imaging compensation method and system based on a voice coil motor, and an imaging method and system.
为了解决上述技术问题,本发明提供了一种基于音圈电机的光声扫描成像补偿方法,包括:步骤S1,获取首次运动各设定出光位置;步骤S2,根据各设定出光位置获取与各设定出光位置相对应的实际出光位置;步骤S3,执行步骤S4或者步骤S5;步骤S4,判断各实际出光位置与相应设定出光位置的偏差值是否均满足要求;若否,则根据各实际出光位置对各设定出光位置进行补偿,获得各补偿出光位置,将各补偿出光位置作为下次运动的各设定出光位置,执行步骤S2;若是,则将该次运动的各设定出光位置作为满足需求的各设定出光位置输出;步骤S5,根据各实际出光位置对各设定出光位置进行补偿,获得各补偿出光位置,将各补偿出光位置作为下次运动的各设定出光位置,执行步骤S2,且补偿次数满足预设次数后,将该次各补偿出光位置作为满足需求的各设定出光位置输出。In order to solve the above technical problems, the present invention provides a photoacoustic scanning imaging compensation method based on a voice coil motor. Set the actual light-emitting position corresponding to the light-emitting position; step S3, execute step S4 or step S5; step S4, judge whether the deviation value of each actual light-emitting position and the corresponding set light-emitting position meets the requirements; if not, according to each actual light-emitting position. The light emitting position compensates each set light emitting position, obtains each compensated light emitting position, uses each compensated light emitting position as each set light emitting position of the next movement, and executes step S2; Output as each set light emitting position that meets the requirements; step S5, compensate each set light emitting position according to each actual light emitting position, obtain each compensated light emitting position, and use each compensated light emitting position as each set light emitting position of the next movement, Step S2 is performed, and after the compensation times meet the preset times, each of the compensated light-emitting positions is output as each set light-emitting position that meets the requirements.
进一步的,步骤S1包括:设定首次运动的起始位置Sstart;设定首次运动的出光间距Sp;则首次运动各设定出光位置为:SFirst[n]=Sstart+Sp×(n-1);其中n取大于0的整数。Further, step S1 includes: setting the starting position Sstart of the first movement; setting the light-emitting distance Sp of the first movement; then the set light-emitting positions of the first movement are: SFirst[n]=Sstart+Sp×(n-1) ; where n is an integer greater than 0.
进一步的,步骤S2包括:根据STempm[n],获取Sm[n];其中STempm[n]为第m次运动各设定出光位置,且STemp1[n]=SFirst[n];Sm[n]为第m次运动各实际出光位置。Further, step S2 includes: obtaining S m [n] according to STemp m [n]; wherein STemp m [n] is the light output position set for the mth movement, and STemp 1 [n]=SFirst[n]; S m [n] is the actual light-emitting position of the m-th movement.
进一步的,步骤S4中判断式为:|Sm[n]-SFirst[n]|≤A;其中,A为偏差值;若不满足所述判断式,则根据Sm[n]对STempm[n]进行补偿,获得各补偿出光位置STTLm[n],令STempm+1[n]=STTLm[n],执行步骤S2;若满足所述判断式,则将该次运动的STempm[n]作为满足需求的各设定出光位置输出。Further, the judgment formula in step S4 is: |S m [n]-SFirst[n]|≤A; wherein, A is the deviation value; if the judgment formula is not satisfied, then STemp m is determined according to S m [n] [n] Perform compensation to obtain each compensated light output position STTL m [n], let STemp m+1 [n]=STTL m [n], and execute step S2; if the judgment formula is satisfied, then the STemp of this movement m [n] is output as each set light output position that meets the requirements.
进一步的,步骤S5包括:根据Sm[n]对STempm[n]进行补偿,获得各补偿出光位置STTLm[n],令STempm+1[n]=STTLm[n],执行步骤S2;在m=w时,将STTLm[n]作为满足需求的各设定出光位置输出。Further, step S5 includes: compensating STemp m [n] according to S m [n] to obtain each compensated light output position STTL m [n], let STemp m+1 [n]=STTL m [n], and execute the step S2: When m=w, output the STTL m [n] as each set light output position that meets the requirements.
进一步的,所述根据Sm[n]对STempm[n]进行补偿,获得各补偿出光位置STTLm[n]包括:STTLm[n]=STempm[n]-(Sm[n]-SFirst[n])。Further, performing compensation on STemp m [n] according to S m [n] to obtain each compensated light output position STTL m [n] includes: STTL m [n]=STemp m [n]-(S m [n] -SFirst[n]).
进一步的,所述偏差值为光栅尺的分辨率的若干倍。Further, the deviation value is several times the resolution of the grating ruler.
又一方面,本发明提供了一种基于音圈电机的光声扫描成像方法,包括:根据满足需求的各设定出光位置向激光器发送发光指令;激光器根据发光指令发光;获取样品经激光照射后的超声信号,以进行成像;其中所述满足需求的各设定出光位置适于采用如上所述的基于音圈电机的光声扫描成像补偿方法获取。In another aspect, the present invention provides a photoacoustic scanning imaging method based on a voice coil motor, comprising: sending a light-emitting command to the laser according to each set light-emitting position that meets the requirements; the laser emits light according to the light-emitting command; The ultrasonic signal is obtained for imaging; wherein each set light output position that meets the requirements is suitable for acquisition by the above-mentioned photoacoustic scanning imaging compensation method based on the voice coil motor.
又一方面,本发明提供了一种基于音圈电机的光声扫描成像系统,包括:激光器,用于发射激光;扫描头,其上设置有反射镜和超声波探头,其中所述反射镜用于将激光器发射的激光反射至样品,所述超声波探头用于接收样品被激光照射后发出的超声波信号;驱动器,用于驱动扫描头往返运动;位置采集模块,用于采集扫描头的运动位置;分光探头,用于采集激光器发射激光的分光束;信号处理器,与激光器、位置采集模块、分光探头电性相连;以及上位机,所述驱动器、信号处理器、超声波探头均与上位机电性相连;其中所述上位机适于控制驱动器驱动扫描头往返运动,并向信号处理器发送首次运动各设定出光位置,所述信号处理器适于在扫描头的运动位置符合各设定出光位置时向激光器发送发光指令,所述信号处理器适于通过分光探头、位置采集模块获取各设定出光位置相对应的实际出光位置;以及所述信号处理器适于采用如上所述的基于音圈电机的光声扫描成像补偿方法获取满足需求的各设定出光位置,并根据满足需求的各设定出光位置向激光器发送发光指令,所述超声波探头适于接收样品被激光照射后发出的超声波信号并传输给上位机以进行成像。In yet another aspect, the present invention provides a photoacoustic scanning imaging system based on a voice coil motor, comprising: a laser for emitting laser light; a scanning head on which a reflecting mirror and an ultrasonic probe are arranged, wherein the reflecting mirror is used for The laser emitted by the laser is reflected to the sample, and the ultrasonic probe is used to receive the ultrasonic signal emitted by the sample after being irradiated by the laser; the driver is used to drive the scanning head to move back and forth; the position acquisition module is used to collect the moving position of the scanning head; The probe is used to collect the split beam of the laser emitted by the laser; the signal processor is electrically connected with the laser, the position acquisition module and the spectroscopic probe; and the host computer, the driver, the signal processor and the ultrasonic probe are all electrically connected with the host computer; The host computer is adapted to control the driver to drive the scanning head to move back and forth, and send each set light-emitting position for the first movement to the signal processor, and the signal processor is adapted to send a signal to the signal processor when the moving position of the scanning head matches each of the set light-emitting positions. The laser sends a light-emitting instruction, and the signal processor is adapted to obtain the actual light-emitting position corresponding to each set light-emitting position through the spectroscopic probe and the position acquisition module; The photoacoustic scanning imaging compensation method obtains each set light-emitting position that meets the requirements, and sends light-emitting instructions to the laser according to each set light-emitting position that meets the requirements. to the host computer for imaging.
又一方面,本发明提供了一种基于音圈电机的光声扫描成像补偿系统,包括:设定出光位置获取模块,适于获取各设定出光位置;实际出光位置获取模块,适于根据各设定出光位置获取与各设定出光位置相对应的实际出光位置;处理模块;其中所述处理模块适于判断各实际出光位置与相应设定出光位置的偏差值是否均满足要求;若否,则根据各实际出光位置对各设定出光位置进行补偿,获得各补偿出光位置,将各补偿出光位置作为下次运动的各设定出光位置,并传输给设定出光位置获取模块;若是,则将该次运动的各设定出光位置作为满足需求的各设定出光位置输出;或者所述处理模块适于根据各实际出光位置对各设定出光位置进行补偿,获得各补偿出光位置,将各补偿出光位置作为下次运动的各设定出光位置,并传输给设定出光位置获取模块,且补偿次数满足预设次数后,将该次各补偿出光位置作为满足需求的各设定出光位置输出。In another aspect, the present invention provides a photoacoustic scanning imaging compensation system based on a voice coil motor, including: a set light exit position acquisition module, suitable for acquiring each set light exit position; an actual light exit position acquisition module, suitable for Setting the light-emitting position to obtain the actual light-emitting position corresponding to each set light-emitting position; a processing module; wherein the processing module is suitable for judging whether the deviation value of each actual light-emitting position and the corresponding set light-emitting position meets the requirements; if not, Then compensate each set light emitting position according to each actual light emitting position, obtain each compensated light emitting position, use each compensated light emitting position as each set light emitting position of the next movement, and transmit it to the set light emitting position acquisition module; if yes, then Each set light emitting position of this movement is output as each set light emitting position that meets the requirements; or the processing module is suitable for compensating each set light emitting position according to each actual light emitting position to obtain each compensated light emitting position, and each The compensated light-emitting position is used as each set light-emitting position of the next movement, and is transmitted to the set light-emitting position acquisition module, and after the compensation times meet the preset times, the compensated light-emitting positions are output as the set light-emitting positions that meet the requirements .
本发明的有益效果是,本发明可以通过预规划补偿的运动控制实现高速状态下的等间距输出,实现高速,高分辨率,无失真的成像功能。The beneficial effect of the present invention is that the present invention can realize equidistant output in high-speed state through motion control of pre-planning and compensation, and realize high-speed, high-resolution, and distortion-free imaging functions.
本发明的其他特征和优点将在随后的说明书中阐述,并且,部分地从说明书中变得显而易见,或者通过实施本发明而了解。本发明的目的和其他优点在说明书、权利要求书以及附图中所特别指出的结构来实现和获得。Other features and advantages of the present invention will be set forth in the description which follows, and in part will be apparent from the description, or may be learned by practice of the invention. The objectives and other advantages of the invention will be realized and attained by the structure particularly pointed out in the description, claims and drawings.
为使本发明的上述目的、特征和优点能更明显易懂,下文特举较佳实施例,并配合所附附图,作详细说明如下。In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, preferred embodiments are given below, and are described in detail as follows in conjunction with the accompanying drawings.
附图说明Description of drawings
为了更清楚地说明本发明具体实施方式或现有技术中的技术方案,下面将对具体实施方式或现有技术描述中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图是本发明的一些实施方式,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其他的附图。In order to illustrate the specific embodiments of the present invention or the technical solutions in the prior art more clearly, the following briefly introduces the accompanying drawings that need to be used in the description of the specific embodiments or the prior art. Obviously, the accompanying drawings in the following description The drawings are some embodiments of the present invention. For those of ordinary skill in the art, other drawings can also be obtained based on these drawings without creative efforts.
图1为本发明的实施例的基于音圈电机的光声扫描成像补偿方法的流程图;FIG. 1 is a flowchart of a photoacoustic scanning imaging compensation method based on a voice coil motor according to an embodiment of the present invention;
图2为本发明的实施例的基于音圈电机的光声扫描成像方法的流程图;2 is a flow chart of a photoacoustic scanning imaging method based on a voice coil motor according to an embodiment of the present invention;
图3为本发明的实施例的基于音圈电机的光声扫描成像系统的示意图;3 is a schematic diagram of a photoacoustic scanning imaging system based on a voice coil motor according to an embodiment of the present invention;
图4是本发明的实施例的信号示意图。FIG. 4 is a signal schematic diagram of an embodiment of the present invention.
具体实施方式Detailed ways
为使本发明实施例的目的、技术方案和优点更加清楚,下面将结合附图对本发明的技术方案进行清楚、完整地描述,显然,所描述的实施例是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。In order to make the purposes, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the present invention, but not all of them. example. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.
实际社会生产、生活中,有些应用需要高分辨率、小行程(<1mm)、高速扫描,因此我们利用音圈电机高速震荡的特性,配合预规划补偿位置算法实现激光等间距输出,实现光声成像在光学分辨率模式下的高速,高分辨率,无失真的成像功能。In actual social production and life, some applications require high resolution, small stroke (<1mm), and high-speed scanning. Therefore, we use the characteristics of high-speed oscillation of the voice coil motor, and cooperate with the pre-planned compensation position algorithm to achieve equal-spaced laser output and photoacoustic. High-speed, high-resolution, distortion-free imaging capabilities in optical resolution mode.
如图3所示,是一种可选的基于音圈电机的光声扫描成像系统。As shown in Figure 3, it is an optional voice coil motor-based photoacoustic scanning imaging system.
成像过程imaging process
激光1经过聚焦镜2聚焦,通过反射镜4经过声透镜5照射在样品10上,超声波探头7接收样品10被激光1照射后发出的超声波信号,经过二级放大后通过采集卡传输至上位机。The
运动方式sports
聚焦镜2、三角镜3、反射镜4、声透镜5和超声波探头7固定于音圈电机的运动线圈6;驱动器根据运动控制卡的规划脉冲产生电流至运动线圈6,运动线圈6产生磁力,在左右磁铁作用下产生高频换向力,使得运动线圈6及其固定元件可以延直线轨道8形成高频往返运动。The focusing
信号传递signaling
首先在上位机软件设定指令,将一系列的运动点位置与时间写入到控制卡中,控制卡将规划曲线转换为脉冲信号给驱动器,驱动器将脉冲信号转换为驱动电流,控制电机做高速往返运动,光栅尺9将运动线圈6运动的位置信号(差分脉冲)传输至FPGA信号处理器,上位机发送扫描开始指令和终点位置以及激光1的触发间距到FPGA信号处理器,FPGA信号处理器根据光栅尺9的脉冲电平和脉冲数,判断电机从起始位到终点位置间并正向运动触发间距时发出一个脉冲信号到激光器,或者判断电机从终点到起始位位置间并负向运动触发间距时发出一个脉冲信号到激光器,实现激光器在往返运动过程中实现从起始位到终点位置间的出光,但是因为电子系统和激光器从FPGA发出一个触发信号到激光器出光会有一个信号延迟,激光1通过分光镜11进行光束分束,通过光电探头12将实际出光时刻的脉冲信号发送至FPGA,FPGA记录各设定出光位置和各实际出光位置,并进行补偿,从而获取满足满足需求的各设定出光位置,并根据其控制激光器出光,以使各实际出光位置间距近乎相等,从而可获得高分辨率、无失真的成像。First, set the command in the host computer software, write a series of moving point positions and time into the control card, the control card converts the planning curve into a pulse signal to the driver, and the driver converts the pulse signal into a driving current to control the motor to operate at high speed. During the reciprocating motion, the
如图1所示,本实施例提供了一种基于音圈电机的光声扫描成像补偿方法,包括:As shown in FIG. 1 , this embodiment provides a photoacoustic scanning imaging compensation method based on a voice coil motor, including:
步骤S1,获取首次运动各设定出光位置;Step S1, obtaining each set light-emitting position of the first movement;
步骤S2,根据各设定出光位置获取与各设定出光位置相对应的实际出光位置;Step S2, obtaining the actual light emitting position corresponding to each set light emitting position according to each set light emitting position;
步骤S3,执行步骤S4或者步骤S5;Step S3, execute step S4 or step S5;
步骤S4,判断各实际出光位置与相应设定出光位置的偏差值是否均满足要求;Step S4, judging whether the deviation value of each actual light-emitting position and the corresponding set light-emitting position meets the requirements;
若否,则根据各实际出光位置对各设定出光位置进行补偿,获得各补偿出光位置,将各补偿出光位置作为下次运动的各设定出光位置,执行步骤S2;If not, compensate each set light emitting position according to each actual light emitting position, obtain each compensated light emitting position, use each compensated light emitting position as each set light emitting position of the next movement, and execute step S2;
若是,则将该次运动的各设定出光位置作为满足需求的各设定出光位置输出;If yes, output the set light-emitting positions of this movement as the set light-emitting positions that meet the requirements;
步骤S5,根据各实际出光位置对各设定出光位置进行补偿,获得各补偿出光位置,将各补偿出光位置作为下次运动的各设定出光位置,执行步骤S2,且补偿次数满足预设次数后,将该次各补偿出光位置作为满足需求的各设定出光位置输出。Step S5: Compensate each set light-emitting position according to each actual light-emitting position, obtain each compensated light-emitting position, use each compensated light-emitting position as each set light-emitting position of the next movement, and execute step S2, and the number of compensations meets the preset number of times. Afterwards, each compensated light-emitting position is output as each set light-emitting position that meets the requirements.
在本实施例中,优选的,步骤S1包括:In this embodiment, preferably, step S1 includes:
设定首次运动的起始位置Sstart;Set the starting position Sstart of the first movement;
设定首次运动的出光间距Sp;Set the light-emitting distance Sp of the first movement;
则首次运动各设定出光位置为:SFirst[n]=Sstart+Sp×(n-1);其中n取大于0的整数。Then, the set light-emitting positions of the first motion are: SFirst[n]=Sstart+Sp×(n-1); wherein n takes an integer greater than 0.
在本实施例中,优选的,步骤S2包括:根据STempm[n],获取Sm[n];In this embodiment, preferably, step S2 includes: obtaining S m [n] according to STemp m [n];
其中STempm[n]为第m次运动各设定出光位置,且STemp1[n]=SFirst[n];Sm[n]为第m次运动各实际出光位置。Wherein STemp m [n] is the set light output position of the mth movement, and STemp 1 [n]=SFirst[n]; S m [n] is the actual light output position of the mth movement.
在本实施例中,优选的,步骤S4中判断式为:|Sm[n]-SFirst[n]|≤A;其中,A为偏差值;In this embodiment, preferably, the judgment formula in step S4 is: |S m [n]-SFirst[n]|≤A; wherein, A is the deviation value;
若不满足所述判断式,则根据Sm[n]对STempm[n]进行补偿,获得各补偿出光位置STTLm[n],令STempm+1[n]=STTLm[n],执行步骤S2;If the above judgment formula is not satisfied, then compensate STemp m [n] according to S m [n] to obtain each compensation light output position STTL m [n], let STemp m+1 [n]=STTL m [n], Execute step S2;
若满足所述判断式,则将该次运动的STempm[n]作为满足需求的各设定出光位置输出。If the judgment formula is satisfied, the STemp m [n] of the current movement is output as each set light-emitting position that satisfies the requirement.
在本实施例中,优选的,步骤S5包括:In this embodiment, preferably, step S5 includes:
根据Sm[n]对STempm[n]进行补偿,获得各补偿出光位置STTLm[n],令STempm+1[n]=STTLm[n],执行步骤S2;Compensate STemp m [n] according to S m [n] to obtain each compensated light output position STTL m [n], set STemp m+1 [n]=STTL m [n], and execute step S2;
在m=w时,将STTLm[n]作为满足需求的各设定出光位置输出。When m=w, the STTL m [n] is output as each set light output position satisfying the requirement.
采用步骤S4的补偿方法,可以在各设定出光位置一获取满足需求时,即可输出;而步骤S5的补偿方法,其可以根据经验设置w的值,比如在一种可选的应用场景中,经过经验积累,一般在经过31次、35次、37次补偿后,即可满足要求,但是输出时的次数不固定,那么根据经验可以把w设置成40次,即固定补偿40次后即输出满足需求的各设定出光位置输出,已进行后续的成像。Using the compensation method of step S4, the output can be output as soon as each set light-emitting position is obtained to meet the requirements; and the compensation method of step S5, the value of w can be set according to experience, for example, in an optional application scenario , after accumulated experience, generally after 31 times, 35 times, and 37 times of compensation, the requirements can be met, but the number of times of output is not fixed, then according to experience, w can be set to 40 times, that is, after 40 times of fixed compensation The output of each set light output position that meets the requirements is output, and subsequent imaging has been performed.
因此,步骤S4和S5可以根据实际需求选择执行。Therefore, steps S4 and S5 can be selected and executed according to actual needs.
在本实施例中,优选的,所述根据Sm[n]对STempm[n]进行补偿,获得各补偿出光位置STTLm[n]包括:In this embodiment, preferably, performing compensation on STemp m [n] according to S m [n] to obtain each compensated light exit position STTL m [n] includes:
STTLm[n]=STempm[n]-(Sm[n]-SFirst[n])。STTL m [n]= STempm [n]-(Sm[n] -SFirst [n]).
在本实施方式中,获得各补偿出光位置STTLm[n]即是为了把每次各实际出光位置向相应的首次运动设定出光位置拟合,以使偏差值满足需求,从而获得清晰图像。In this embodiment, obtaining each compensated light-emitting position STTL m [n] is to fit each actual light-emitting position to the corresponding first-time set light-emitting position, so that the deviation value satisfies the requirement, thereby obtaining a clear image.
在本实施例中,优选的,所述偏差值为光栅尺的分辨率的若干倍。例如,当光栅尺分辨率为0.1μm时,偏差值可以取其5倍,即0.5μm。In this embodiment, preferably, the deviation value is several times the resolution of the grating ruler. For example, when the resolution of the grating scale is 0.1 μm, the deviation value can be taken as 5 times, that is, 0.5 μm.
在上述实施例的基础上,如图2所示,本实施例提供了一种基于音圈电机的光声扫描成像方法,包括:根据满足需求的各设定出光位置向激光器发送发光指令;激光器根据发光指令发光;获取样品经激光照射后的超声信号,以进行成像;其中所述满足需求的各设定出光位置适于采用如上所述的基于音圈电机的光声扫描成像补偿方法获取。On the basis of the above embodiment, as shown in FIG. 2 , this embodiment provides a photoacoustic scanning imaging method based on a voice coil motor, which includes: sending a light-emitting instruction to the laser according to each set light-emitting position that meets the requirements; Lighting according to the light-emitting instruction; acquiring the ultrasonic signal of the sample after being irradiated by the laser for imaging; wherein each set light-emitting position that meets the requirements is suitable to be obtained by the above-mentioned photoacoustic scanning imaging compensation method based on the voice coil motor.
在上述实施例的基础上,如图3所示,本实施例提供了一种基于音圈电机的光声扫描成像系统,包括:激光器,用于发射激光;扫描头,其上设置有反射镜和超声波探头,其中所述反射镜用于将激光器发射的激光反射至样品,所述超声波探头用于接收样品被激光照射后发出的超声波信号;驱动器,用于驱动扫描头往返运动;位置采集模块,用于采集扫描头的运动位置;分光探头,用于采集激光器发射激光的分光束;信号处理器,与激光器、位置采集模块、分光探头电性相连;以及上位机,所述驱动器、信号处理器、超声波探头均与上位机电性相连;其中所述上位机适于控制驱动器驱动扫描头往返运动,并向信号处理器发送首次运动各设定出光位置,所述信号处理器适于在扫描头的运动位置符合各设定出光位置时向激光器发送发光指令,所述信号处理器适于通过分光探头、位置采集模块获取各设定出光位置相对应的实际出光位置;以及所述信号处理器适于采用如上所述的基于音圈电机的光声扫描成像补偿方法获取满足需求的各设定出光位置,并根据满足需求的各设定出光位置向激光器发送发光指令,所述超声波探头适于接收样品被激光照射后发出的超声波信号并传输给上位机以进行成像。On the basis of the above embodiment, as shown in FIG. 3 , this embodiment provides a photoacoustic scanning imaging system based on a voice coil motor, including: a laser for emitting laser light; a scanning head on which a mirror is arranged and an ultrasonic probe, wherein the mirror is used to reflect the laser emitted by the laser to the sample, and the ultrasonic probe is used to receive the ultrasonic signal emitted by the sample after being irradiated by the laser; a driver is used to drive the scanning head to move back and forth; a position acquisition module , used to collect the motion position of the scanning head; the spectroscopic probe, used to collect the split beam of the laser emitted by the laser; the signal processor, electrically connected with the laser, the position acquisition module, and the spectroscopic probe; and the host computer, the driver, signal processing Both the device and the ultrasonic probe are electrically connected with the host computer; wherein the host computer is adapted to control the driver to drive the scanning head to move back and forth, and send the first movement to the signal processor to set the light output position, and the signal processor is suitable for the scanning head The signal processor is adapted to obtain the actual light-emitting position corresponding to each set light-emitting position through the spectroscopic probe and the position acquisition module; and the signal processor is adapted to The above-mentioned photoacoustic scanning imaging compensation method based on the voice coil motor is used to obtain each set light-emitting position that meets the requirements, and sends a light-emitting command to the laser according to each set light-emitting position that meets the requirements, and the ultrasonic probe is suitable for receiving. The ultrasonic signal emitted after the sample is irradiated by the laser is transmitted to the upper computer for imaging.
在上述实施例的基础上,本实施例还提供了一种基于音圈电机的光声扫描成像补偿系统,包括:设定出光位置获取模块,适于获取各设定出光位置;实际出光位置获取模块,适于根据各设定出光位置获取与各设定出光位置相对应的实际出光位置;处理模块;其中所述处理模块适于判断各实际出光位置与相应设定出光位置的偏差值是否均满足要求;若否,则根据各实际出光位置对各设定出光位置进行补偿,获得各补偿出光位置,将各补偿出光位置作为下次运动的各设定出光位置,并传输给设定出光位置获取模块;若是,则将该次运动的各设定出光位置作为满足需求的各设定出光位置输出;或者所述处理模块适于根据各实际出光位置对各设定出光位置进行补偿,获得各补偿出光位置,将各补偿出光位置作为下次运动的各设定出光位置,并传输给设定出光位置获取模块,且补偿次数满足预设次数后,将该次各补偿出光位置作为满足需求的各设定出光位置输出。On the basis of the above embodiment, this embodiment also provides a photoacoustic scanning imaging compensation system based on a voice coil motor, including: a set light exit position acquisition module, suitable for acquiring each set light exit position; acquisition of the actual light exit position A module, adapted to obtain the actual light-emitting position corresponding to each set light-emitting position according to each set light-emitting position; a processing module; wherein the processing module is suitable for judging whether the deviation value of each actual light-emitting position and the corresponding set light-emitting position is equal Satisfy the requirements; if not, compensate each set light output position according to each actual light output position, obtain each compensated light output position, use each compensated light output position as each set light output position of the next movement, and transmit it to the set light output position acquisition module; if yes, output the set light-emitting positions of this movement as the set light-emitting positions that meet the requirements; or the processing module is adapted to compensate each set light-emitting position according to the actual light-emitting positions, and obtain each set light-emitting position. Compensate the light-emitting position, take each compensated light-emitting position as each set light-emitting position of the next movement, and transmit it to the set light-emitting position acquisition module, and after the compensation times meet the preset times, the compensated light-emitting position is regarded as the one that meets the requirements. Each set light output position output.
在一种可选的应用场景中,基于音圈电机的光声扫描成像,运动线圈6以1mm 25HZ状态往返运动,最高速可达260mm/s,光栅分辨率0.1μm,激光器从FPGA发出脉冲信号到出光延时15μs,设定等间距3μm出光,补偿前激光触发信号以3μm为步距触发,但激光器以3~6.9μm一个渐变区间出光,无法达到成像标准,经过补偿激光可以实现3.0±0.3μm的等间距出光,保证图像在高速状态下不失真。In an optional application scenario, based on the photoacoustic scanning imaging of the voice coil motor, the moving coil 6 moves back and forth in a 1mm 25HZ state, the maximum speed can reach 260mm/s, the grating resolution is 0.1μm, and the laser sends out pulse signals from the FPGA The delay to light output is 15μs, and the equal spacing is set to emit light at 3μm. Before compensation, the laser trigger signal is triggered in steps of 3μm, but the laser emits light in a gradual range of 3-6.9μm, which cannot meet the imaging standard. After compensation, the laser can achieve 3.0±0.3 The equidistant light output of μm ensures that the image is not distorted at high speed.
在本申请所提供的几个实施例中,应该理解到,所揭露的装置和方法,也可以通过其它的方式实现。以上所描述的装置实施例仅仅是示意性的,例如,附图中的流程图和框图显示了根据本发明的多个实施例的装置、方法和计算机程序产品的可能实现的体系架构、功能和操作。在这点上,流程图或框图中的每个方框可以代表一个模块、程序段或代码的一部分,所述模块、程序段或代码的一部分包含一个或多个用于实现规定的逻辑功能的可执行指令。也应当注意,在有些作为替换的实现方式中,方框中所标注的功能也可以以不同于附图中所标注的顺序发生。例如,两个连续的方框实际上可以基本并行地执行,它们有时也可以按相反的顺序执行,这依所涉及的功能而定。也要注意的是,框图和/或流程图中的每个方框、以及框图和/或流程图中的方框的组合,可以用执行规定的功能或动作的专用的基于硬件的系统来实现,或者可以用专用硬件与计算机指令的组合来实现。In the several embodiments provided in this application, it should be understood that the disclosed apparatus and method may also be implemented in other manners. The apparatus embodiments described above are merely illustrative, for example, the flowcharts and block diagrams in the accompanying drawings illustrate the architecture, functionality and possible implementations of apparatuses, methods and computer program products according to various embodiments of the present invention. operate. In this regard, each block in the flowchart or block diagrams may represent a module, segment, or portion of code that contains one or more functions for implementing the specified logical function(s) executable instructions. It should also be noted that, in some alternative implementations, the functions noted in the block may occur out of the order noted in the figures. For example, two blocks in succession may, in fact, be executed substantially concurrently, or the blocks may sometimes be executed in the reverse order, depending upon the functionality involved. It is also noted that each block of the block diagrams and/or flowchart illustrations, and combinations of blocks in the block diagrams and/or flowchart illustrations, can be implemented in dedicated hardware-based systems that perform the specified functions or actions , or can be implemented in a combination of dedicated hardware and computer instructions.
另外,在本发明各个实施例中的各功能模块可以集成在一起形成一个独立的部分,也可以是各个模块单独存在,也可以两个或两个以上模块集成形成一个独立的部分。In addition, each functional module in each embodiment of the present invention may be integrated to form an independent part, or each module may exist independently, or two or more modules may be integrated to form an independent part.
所述功能如果以软件功能模块的形式实现并作为独立的产品销售或使用时,可以存储在一个计算机可读取存储介质中。基于这样的理解,本发明的技术方案本质上或者说对现有技术做出贡献的部分或者该技术方案的部分可以以软件产品的形式体现出来,该计算机软件产品存储在一个存储介质中,包括若干指令用以使得一台计算机设备(可以是个人计算机,服务器,或者网络设备等)执行本发明各个实施例所述方法的全部或部分步骤。而前述的存储介质包括:U盘、移动硬盘、只读存储器(ROM,Read-Only Memory)、随机存取存储器(RAM,Random Access Memory)、磁碟或者光盘等各种可以存储程序代码的介质。If the functions are implemented in the form of software function modules and sold or used as independent products, they can be stored in a computer-readable storage medium. Based on this understanding, the technical solution of the present invention can be embodied in the form of a software product in essence, or the part that contributes to the prior art or the part of the technical solution. The computer software product is stored in a storage medium, including Several instructions are used to cause a computer device (which may be a personal computer, a server, or a network device, etc.) to execute all or part of the steps of the methods described in the various embodiments of the present invention. The aforementioned storage medium includes: U disk, mobile hard disk, Read-Only Memory (ROM, Read-Only Memory), Random Access Memory (RAM, Random Access Memory), magnetic disk or optical disk and other media that can store program codes .
以上述依据本发明的理想实施例为启示,通过上述的说明内容,相关工作人员完全可以在不偏离本项发明技术思想的范围内,进行多样的变更以及修改。本项发明的技术性范围并不局限于说明书上的内容,必须要根据权利要求范围来确定其技术性范围。Taking the above ideal embodiments according to the present invention as inspiration, and through the above description, relevant personnel can make various changes and modifications without departing from the technical idea of the present invention. The technical scope of the present invention is not limited to the contents in the specification, and the technical scope must be determined according to the scope of the claims.
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