CN114949591A - TTfield therapy device capable of being adjusted regionally and using method thereof - Google Patents
TTfield therapy device capable of being adjusted regionally and using method thereof Download PDFInfo
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- CN114949591A CN114949591A CN202210624122.2A CN202210624122A CN114949591A CN 114949591 A CN114949591 A CN 114949591A CN 202210624122 A CN202210624122 A CN 202210624122A CN 114949591 A CN114949591 A CN 114949591A
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- 238000002560 therapeutic procedure Methods 0.000 title claims abstract description 14
- 238000000034 method Methods 0.000 title claims abstract description 13
- 206010028980 Neoplasm Diseases 0.000 claims abstract description 12
- 239000000919 ceramic Substances 0.000 claims abstract description 11
- 230000005672 electromagnetic field Effects 0.000 claims abstract description 5
- 230000005684 electric field Effects 0.000 claims description 15
- 238000011369 optimal treatment Methods 0.000 claims description 6
- 238000002591 computed tomography Methods 0.000 claims description 5
- 238000002595 magnetic resonance imaging Methods 0.000 claims description 3
- 238000004088 simulation Methods 0.000 claims description 3
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 238000011282 treatment Methods 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 5
- 238000010438 heat treatment Methods 0.000 abstract description 2
- 238000010586 diagram Methods 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 206010027406 Mesothelioma Diseases 0.000 description 1
- 206010033128 Ovarian cancer Diseases 0.000 description 1
- 206010061535 Ovarian neoplasm Diseases 0.000 description 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000746 body region Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 201000007983 brain glioma Diseases 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 201000007270 liver cancer Diseases 0.000 description 1
- 208000014018 liver neoplasm Diseases 0.000 description 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 description 1
- 208000011645 metastatic carcinoma Diseases 0.000 description 1
- 206010061289 metastatic neoplasm Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 201000002528 pancreatic cancer Diseases 0.000 description 1
- 208000008443 pancreatic carcinoma Diseases 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Electrotherapy Devices (AREA)
Abstract
The invention provides a TTfield therapy device capable of being adjusted in a region and a using method thereof, which consists of a power supply, a host, a junction box and an electrode plate, wherein the electrode plate comprises a plurality of working regions, each working region is provided with a plurality of ceramic electrodes and temperature sensors, and the junction box is provided with a knob switch and an indicator light; the invention can reduce the influence of the electromagnetic field received by the non-tumor area, simultaneously reduce the heating condition of the focus area of the patient, improve the body comfort of the patient during treatment and achieve better treatment effect.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to a TTfield therapy device capable of being adjusted regionally and a using method thereof.
Background
The electric field therapy is an in vitro non-invasive tumor removal technology, and the electric field therapy is widely concerned by the medical field in the aspect of treating solid tumors including brain glioma, brain metastatic carcinoma, mesothelioma, pancreatic cancer, non-small cell alveolar, liver cancer, ovarian cancer and other tumors.
In the case of TTField, where the electrode array has provided a strong field strength to the tumor region at the site of the patient's lesion, the in vivo and in vitro studies have shown that the efficacy of TTField therapy increases with increasing field strength at the target region, which depends on where the electrode array is placed at the patient's lesion and the magnitude of the electrode array current.
The existing product has the following defects: the electrode array product shape structure that the patient used is fixed, and the electric field direction and the size that the patient received in the use are also fixed, and the tumour position and the size that different patients correspond all differ, and simple increase electric field intensity can lead to the temperature rise of patient's focus position, lets the patient feel uncomfortable, is difficult to continue the treatment, accomplishes differentiation treatment to various different situations and hardly accomplishes, and the effect of whole treatment can not reach the expectation.
Disclosure of Invention
The invention aims to solve the problems mentioned in the background technology and provides a TTfield therapy device capable of being adjusted in a region and a using method thereof, wherein the TTfield therapy device consists of a power supply, a host, a junction box and an electrode plate, the power supply, the host, the junction box and the electrode plate are electrically connected, the electrode plate comprises a plurality of working regions, the working regions are mutually independent, a plurality of ceramic electrodes and temperature sensors are arranged in the working regions, a plurality of groups of switches and indicator lamps are arranged on the junction box, and each group of switches and indicator lamps is correspondingly connected with one working region through a wiring harness; the using method comprises the following steps:
s1, scanning a focus part by a patient through CT (computed tomography) or magnetic resonance imaging equipment and the like to confirm tumor position and size information;
s2, the host computer utilizes finite element analysis to simulate the electromagnetic field distribution in the body area caused by the electrodes according to the image data to find the optimal treatment area;
s3, according to the optimal treatment area, the host machine is communicated with the required working area circuit through software, other working area circuits are disconnected, and the indicator light corresponding to the communicated working area is turned on;
s4, when the circuits of the working areas are communicated, the temperature of the electric field is increased, the temperature sensor monitors the temperature in real time, the corresponding indicator light is displayed in red when the temperature is higher than a warning value, and the corresponding indicator light is displayed in green when the temperature is lower than the warning value;
s5, the patient can control the current of the corresponding working area through adjusting a knob switch according to the bearing capacity of the patient body, so that the electric field intensity is controlled.
Preferably, the ceramic electrodes in each working area are electrically connected, and the ceramic electrodes in different working areas are not connected.
Preferably, the host can control the on-off of the circuit of each working area through software.
Preferably, the switch is a knob switch, the knob switch can adjust the current value of the corresponding working area, the minimum value of the current is zero, and the maximum value is a parameter set value.
Preferably, the color of the indicator light can be switched, and the indicator light is displayed in red when the temperature of the corresponding working area is higher than a warning value, and is displayed in green when the temperature of the corresponding working area is lower than the warning value.
The host computer analyzes and controls the corresponding working area to start normal work according to the image data, the indicator light of the communicated working area is lighted to be green, when a certain temperature sensor monitors that the temperature of the corresponding working area reaches a warning value, the indicator light corresponding to the working area is changed into red, and the fact that the temperature of the working area is higher and causes discomfort to a human body is prompted and informed, a patient can adjust the knob switch to reduce the current according to the self condition so as to reduce the electric field intensity of the working area, and when the temperature is reduced below the warning value, the corresponding indicator light is changed into green, the patient can adjust the knob switch to increase the current so as to strengthen the electric field intensity of the working area and improve the treatment effect; the more the number of the working areas divided by the electrode plates is, the smaller the area of a single working area is, and the stronger the temperature accurate control capability is.
The invention has the beneficial effects that:
1. the invention can reduce the influence of electromagnetic field on non-tumor area, thus reducing unnecessary energy loss and maximizing the energy utilization of the device;
2. the invention can effectively reduce the heating condition of the focus area of the patient, improve the body comfort of the patient during treatment and achieve better treatment effect.
Drawings
Fig. 1 is a schematic structural diagram of an embodiment of the present invention.
Fig. 2 is a schematic structural view of the electrode sheet.
Fig. 3 is a schematic structural diagram of the distribution box.
Fig. 4 is a schematic diagram of the electric field simulation of the present invention.
In the figure: 1. the device comprises an electrode plate, a junction box 2, a host 3, a power supply 4, a working area 5, a ceramic electrode 6, a temperature sensor 7, a knob switch 8 and an indicator lamp 9.
Detailed Description
The invention is further described below with reference to the drawings and examples.
The TTField therapy device with the adjustable region and the use method thereof as shown in fig. 1 comprises four electrode plates 1, a junction box 2, a main machine 3 and a power supply 4, wherein the power supply 4 is electrically connected with the main machine 3, the main machine 3 is electrically connected with the junction box 2, and the junction box 2 is electrically connected with the electrode plates 1.
As shown in fig. 2, the electrode plate 1 is divided into four working areas 5, each working area 5 is provided with a plurality of ceramic electrodes 6 and a temperature sensor 7, the ceramic electrodes 6 of each working area 5 are connected in series and are separated from the ceramic electrodes 6 of other working areas 5, and the temperature sensors 7 are used for monitoring the temperature of the working area 5.
As shown in fig. 3, the junction box 2 has four ports respectively corresponding to the four electrode plates 1, each port has four sets of knob switches 8 and indicator lamps 9, and each set of knob switches 8 and indicator lamps 9 respectively corresponds to a working area in one electrode plate 1.
As the electric field simulation schematic diagram shown in fig. 4, the invention can control the on-off of the circuit of the working area according to the optimal treatment area, the electric field intensity lines of the tumor position in the diagram are dense, and other areas are loose, thereby achieving the purpose of pertinently treating the cancer area.
When in use, firstly, a patient scans a focus part through CT or magnetic resonance imaging equipment and the like to confirm the size information of a tumor position, the host machine 3 simulates the electromagnetic field distribution in a body region caused by electrodes by utilizing finite element analysis according to image data to find an optimal treatment region, then the host machine 3 is communicated with a required working region 5 circuit through software to disconnect other working region 5 circuits, an indicator lamp 9 corresponding to the communicated working region 5 is lightened, when a certain temperature sensor 7 monitors that the temperature of the corresponding working region 5 reaches a warning value, the indicator lamp 9 corresponding to the working region 5 is changed into red, the indication informs that the working region 5 is higher in temperature and causes discomfort to the human body, the patient can adjust a knob switch 8 to reduce the current according to the self condition, thereby reducing the electric field intensity of the working region 5, and when the temperature is reduced below the warning value, the corresponding indicator lamp 9 is changed into green, the patient can adjust the knob switch 8 to increase the current, thereby strengthening the electric field intensity of the working area 5 and improving the treatment effect.
The above is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above-mentioned embodiments, and all technical solutions belonging to the idea of the present invention belong to the protection scope of the present invention. It should be noted that modifications and embellishments within the scope of the invention may be made by those skilled in the art without departing from the principle of the invention.
Claims (5)
1. A can regulate TTfield therapeutic device and its operation method regionally, it is made up of power, host computer, junction box and electrode plate, the said power is connected with host computer, host computer and junction box, the junction box is connected with electrode plate electrically, its characteristic is: the electrode plate comprises a plurality of working areas which are mutually independent, a plurality of ceramic electrodes and temperature sensors are arranged in the working areas, a plurality of groups of switches and indicator lamps are arranged on the junction box, and each group of switches and indicator lamps is correspondingly connected with one working area through a wire harness; the using method comprises the following steps:
s1, scanning a focus part by a patient through CT (computed tomography) or magnetic resonance imaging equipment and the like to confirm tumor position and size information;
s2, analyzing the electromagnetic field distribution in the body area caused by the simulation electrode according to the image data by the host to find the optimal treatment area;
s3, according to the optimal treatment area, the host machine is communicated with the required working area circuit through software, other working area circuits are disconnected, and the indicator light corresponding to the communicated working area is turned on;
s4, when the circuits of the working areas are communicated, the temperature of the electric field rises, the temperature sensor monitors the temperature in real time, the corresponding indicator light changes color when the temperature is higher than the warning value, and the corresponding indicator light restores color when the temperature is lower than the warning value;
s5, the patient can control the current of the corresponding working area through a switch according to the bearing capacity of the patient body, so that the electric field intensity is controlled.
2. The device and method of using the device according to claim 1, wherein the TTField therapy device comprises: the ceramic electrodes in each working area are electrically connected, and the ceramic electrodes in different working areas are not connected.
3. The device and method of using the device according to claim 1, wherein the TTField therapy device comprises: the host can control the on-off of the circuit of each working area through software.
4. The device and method of using the device according to claim 1, wherein the TTField therapy device comprises: the switch is a knob switch, the knob switch can adjust the current value of the corresponding working area, the minimum value of the current is zero, and the maximum value is a parameter set value.
5. The device and method of using the device according to claim 1, wherein the TTField therapy device comprises: the color of the indicating lamp can be switched, the indicating lamp displays red when the temperature of the corresponding working area is higher than the warning value, and the indicating lamp displays green when the temperature of the corresponding working area is lower than the warning value.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210624122.2A CN114949591A (en) | 2022-06-03 | 2022-06-03 | TTfield therapy device capable of being adjusted regionally and using method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210624122.2A CN114949591A (en) | 2022-06-03 | 2022-06-03 | TTfield therapy device capable of being adjusted regionally and using method thereof |
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| CN114949591A true CN114949591A (en) | 2022-08-30 |
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| CN202210624122.2A Pending CN114949591A (en) | 2022-06-03 | 2022-06-03 | TTfield therapy device capable of being adjusted regionally and using method thereof |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1976738A (en) * | 2004-04-23 | 2007-06-06 | 诺沃库勒有限公司 | Treating a tumor or the like with an electric field |
| CN110234394A (en) * | 2016-12-13 | 2019-09-13 | 兹夫·波姆森 | Treating patients with TTFields with electrode positions optimized with deformable templates |
| CN111420271A (en) * | 2020-04-02 | 2020-07-17 | 河北普尼医疗科技有限公司 | Electrode patch positioning method based on head tumor treatment |
| CN113289247A (en) * | 2021-05-20 | 2021-08-24 | 杭州维那泰克医疗科技有限责任公司 | Electrode patch and cell division suppression device |
| CN114099955A (en) * | 2021-12-22 | 2022-03-01 | 江苏海莱新创医疗科技有限公司 | Electrode patch and tumor electric field treatment system |
| CN114534092A (en) * | 2022-02-28 | 2022-05-27 | 湖南安泰康成生物科技有限公司 | Electrode attachment position determination method and device and computer-readable storage medium |
-
2022
- 2022-06-03 CN CN202210624122.2A patent/CN114949591A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7565205B2 (en) * | 2000-02-17 | 2009-07-21 | Standen Ltd. | Treating a tumor or the like with electric fields at different orientations |
| CN1976738A (en) * | 2004-04-23 | 2007-06-06 | 诺沃库勒有限公司 | Treating a tumor or the like with an electric field |
| CN110234394A (en) * | 2016-12-13 | 2019-09-13 | 兹夫·波姆森 | Treating patients with TTFields with electrode positions optimized with deformable templates |
| CN111420271A (en) * | 2020-04-02 | 2020-07-17 | 河北普尼医疗科技有限公司 | Electrode patch positioning method based on head tumor treatment |
| CN113289247A (en) * | 2021-05-20 | 2021-08-24 | 杭州维那泰克医疗科技有限责任公司 | Electrode patch and cell division suppression device |
| CN114099955A (en) * | 2021-12-22 | 2022-03-01 | 江苏海莱新创医疗科技有限公司 | Electrode patch and tumor electric field treatment system |
| CN114534092A (en) * | 2022-02-28 | 2022-05-27 | 湖南安泰康成生物科技有限公司 | Electrode attachment position determination method and device and computer-readable storage medium |
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Application publication date: 20220830 |