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CN114868924A - A kind of composition based on D-ribose and amino acid and application thereof - Google Patents

A kind of composition based on D-ribose and amino acid and application thereof Download PDF

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CN114868924A
CN114868924A CN202210519135.3A CN202210519135A CN114868924A CN 114868924 A CN114868924 A CN 114868924A CN 202210519135 A CN202210519135 A CN 202210519135A CN 114868924 A CN114868924 A CN 114868924A
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ribose
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amino acid
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陈泽旭
周冰雨
白玲玲
严子航
单梦达
陈裕乐
黄云
刘诗怡
朱园园
古双喜
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Wuhan Institute of Technology
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/38Other non-alcoholic beverages
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/175Amino acids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

本发明公开了一种基于D‑核糖和氨基酸的组合物及其应用。该组合物包括:第一组分、第二组分、第三组分、第四组分;其中,第一组分为D‑核糖,第二组分为赖氨酸、苯丙氨酸、蛋氨酸、苏氨酸、异亮氨酸、亮氨酸、缬氨酸或色氨酸之一或者多种组合,第三组分为麦芽糖或牛磺酸之一或者二者组合,第四组分为茶叶提取物;所述基于D‑核糖和氨基酸的组合物必含有第一组分和第二组分,同时含有第三组分和第四组分的一种或两种组分,且不含有咖啡因或瓜拉纳提取物中的任意一种。该组合物配方合理,用量比例科学,具有明显的迅速补充体力、抗疲劳效果,还具有易于制备、生产成本低等优点,适用于作为功能饮料供给需迅速补充体力和抗疲劳的人群。The invention discloses a D-ribose and amino acid-based composition and its application. The composition comprises: a first component, a second component, a third component, and a fourth component; wherein, the first component is D-ribose, and the second component is lysine, phenylalanine, One or more combinations of methionine, threonine, isoleucine, leucine, valine or tryptophan, the third component is one or a combination of maltose or taurine, and the fourth component It is a tea extract; the D-ribose and amino acid-based composition must contain the first component and the second component, and simultaneously contain one or two components of the third component and the fourth component, and not Contains either caffeine or guarana extract. The composition has a reasonable formula and a scientific dosage ratio, has obvious effects of quickly replenishing physical strength and anti-fatigue, and has the advantages of easy preparation and low production cost, and is suitable for supplying as a functional beverage to people who need to quickly replenish physical strength and resist fatigue.

Description

一种基于D-核糖和氨基酸的组合物及其应用A kind of composition based on D-ribose and amino acid and application thereof

技术领域technical field

本发明涉及食品技术领域,尤其是涉及一种基于D-核糖和氨基酸的组合物及其应用。The present invention relates to the technical field of food, in particular to a D-ribose and amino acid-based composition and its application.

背景技术Background technique

疲劳是人们在连续学习、工作或运动后出现效率下降的一种现象。缓解甚至消除疲劳可以通过充足的睡眠和休息来实现,但这往往需要较长的休息时间;在需要迅速补充体力的情况下(例如竞技体育、加班等),也可以通过服用具有抗疲劳、迅速恢复体力的药物或饮品来实现。然而,目前大多数此类产品要么效果不佳,要么涉及兴奋剂成分,不适合作为功能饮料长期饮用。在具有抗疲劳作用的功能饮品中,有些作用不确切,有些功能饮品含有咖啡因(Caffeine)和瓜拉纳(Guarana,生长在巴西亚玛逊从林中稀有的珍稀果实,其主要成份是瓜拉纳因,化学成分和功能类似于咖啡因)。瓜拉纳同咖啡因副作用近似,容易引起心慌、焦虑、胃痛、心跳加快,长期服用易产生心理依赖,且其兴奋作用持续时间较长容易导致失眠。CN101961345A公开了一种具有抗疲劳作用的药物组合物,包括虫草多糖或发酵虫草菌液、D-核糖和牛磺酸。但该专利以虫草多糖或发酵虫草菌液为主要成分,成本很高,不适合作为大众消费的功能饮料。CN102150724A公开了一种提神缓解体力和视觉疲劳的功能性混合物,含有牛磺酸、咖啡因、绿茶提取物、西洋参提取物、瓜拉纳提取物、银杏叶提取物、枸杞提取物等十余种成分。 CN103816256B报道了一种生理功能的组合物,含有D-核糖、牛磺酸和瓜拉纳提取物或绿咖啡豆提取物。尽管其具有一定的抗疲劳效果,但二者均含有具有明显副作用的咖啡因或瓜拉纳提取物等。Fatigue is a phenomenon in which people experience a decrease in productivity after continuous study, work or exercise. Relief or even eliminate fatigue can be achieved through adequate sleep and rest, but this often requires a long rest period; in the case of need to quickly replenish physical strength (such as competitive sports, overtime, etc.), it can also be achieved by taking anti-fatigue, rapid Rejuvenating drugs or drinks to achieve. However, most of these products are currently either ineffective or involve stimulant ingredients and are not suitable for long-term drinking as an energy drink. Among the functional drinks with anti-fatigue effect, some of them have inaccurate effects. Some functional drinks contain caffeine and guarana, which are rare and rare fruits grown in the Amazon forest in Brazil. The main ingredient is melon. Lanaine, similar in chemical composition and function to caffeine). Guarana has similar side effects to caffeine, and it is easy to cause palpitation, anxiety, stomach pain, and rapid heartbeat. Long-term use can easily lead to psychological dependence, and its stimulant effect lasts for a long time, which can easily lead to insomnia. CN101961345A discloses a pharmaceutical composition with anti-fatigue effect, comprising cordyceps polysaccharide or fermented cordyceps fungus liquid, D-ribose and taurine. However, the patent uses Cordyceps polysaccharide or fermented Cordyceps fungus liquid as the main components, and the cost is very high, so it is not suitable as a functional drink for mass consumption. CN102150724A discloses a functional mixture for refreshing physical strength and visual fatigue, containing more than ten kinds of taurine, caffeine, green tea extract, American ginseng extract, guarana extract, ginkgo biloba extract, wolfberry extract, etc. Element. CN103816256B reports a physiologically functional composition containing D-ribose, taurine and guarana extract or green coffee bean extract. Although it has a certain anti-fatigue effect, both contain caffeine or guarana extract with obvious side effects.

发明内容SUMMARY OF THE INVENTION

本发明的目的在于克服上述技术不足,提出一种基于D-核糖和氨基酸的组合物及其应用,解决现有技术中具有抗疲劳效果的功能组合物抗疲劳效果差或含有咖啡因或瓜拉纳提取物的技术问题。The object of the present invention is to overcome the above-mentioned technical deficiencies, propose a composition based on D-ribose and amino acid and its application, and solve the problem that the functional composition with anti-fatigue effect in the prior art has poor anti-fatigue effect or contains caffeine or guar Technical issues with sodium extracts.

本发明的第一方面提供一种基于D-核糖和氨基酸的组合物,其特征在于,所述基于D-核糖和氨基酸的组合物包括:第一组分、第二组分、第三组分、第四组分;其中,第一组分为D-核糖,第二组分为赖氨酸、苯丙氨酸、蛋氨酸、苏氨酸、异亮氨酸、亮氨酸、缬氨酸或色氨酸之一或者多种组合,第三组分为麦芽糖或牛磺酸之一或者二者组合,第四组分为茶叶提取物;所述基于D-核糖和氨基酸的组合物必含有第一组分和第二组分,同时含有第三组分和第四组分的一种或两种组分,且不含有咖啡因或瓜拉纳提取物中的任意一种。A first aspect of the present invention provides a D-ribose and amino acid-based composition, characterized in that the D-ribose and amino acid-based composition comprises: a first component, a second component, and a third component , the fourth component; wherein, the first component is D-ribose, and the second component is lysine, phenylalanine, methionine, threonine, isoleucine, leucine, valine or One or more combinations of tryptophan, the third component is one or a combination of maltose or taurine, and the fourth component is tea extract; the D-ribose and amino acid-based composition must contain the first The first component and the second component contain one or both of the third component and the fourth component at the same time, and do not contain either caffeine or guarana extract.

本发明的第二方面提供上述基于D-核糖和氨基酸的组合物在制备具有迅速补充体力和抗疲劳作用的产品中的应用。The second aspect of the present invention provides the use of the above-mentioned D-ribose and amino acid-based composition in the preparation of a product with rapid stamina replenishment and anti-fatigue effects.

本发明的第三方面提供一种功能饮料,包括本发明第一方面提供的基于D-核糖和氨基酸的组合物。A third aspect of the present invention provides a functional drink, comprising the D-ribose and amino acid-based composition provided by the first aspect of the present invention.

与现有技术相比,本发明的有益效果包括:Compared with the prior art, the beneficial effects of the present invention include:

该组合物配方合理,用量比例科学,具有明显的迅速补充体力、抗疲劳效果,还具有易于制备、生产成本低等优点,适用于作为功能饮料供给需迅速补充体力和抗疲劳的人群。The composition has a reasonable formula and a scientific dosage ratio, has obvious effects of quickly replenishing physical strength and anti-fatigue, and has the advantages of easy preparation and low production cost, and is suitable for supplying as a functional beverage to people who need to quickly replenish physical strength and resist fatigue.

具体实施方式Detailed ways

为了使本发明的目的、技术方案及优点更加清楚明白,以下结合实施例,对本发明进行进一步详细说明。应当理解,此处所描述的具体实施例仅仅用以解释本发明,并不用于限定本发明。In order to make the objectives, technical solutions and advantages of the present invention clearer, the present invention will be further described in detail below with reference to the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention, but not to limit the present invention.

本发明的第一方面提供一种基于D-核糖和氨基酸的组合物,该基于D- 核糖和氨基酸的组合物含有的第一组分为D-核糖,第二组分为成人必需的 8种氨基酸之一或多种必需氨基酸之组合,第三组分为麦芽糖或牛磺酸之一或者二者组合,第四组分为茶叶提取物;该基于D-核糖和氨基酸的组合物必含有第一组分和第二组分,同时含有第三组分和第四组分的一种或两种组分。该基于D-核糖和氨基酸的组合物不含有咖啡因或瓜拉纳提取物中的任意一种。该基于D-核糖和氨基酸的组合物具有迅速补充体力和抗疲劳效果,适用于需迅速补充体力和抗疲劳的人群。A first aspect of the present invention provides a composition based on D-ribose and amino acid, the first component contained in the composition based on D-ribose and amino acid is D-ribose, and the second component is 8 essential for adults A combination of one or more essential amino acids, the third component is one or a combination of maltose or taurine, and the fourth component is tea extract; the D-ribose and amino acid-based composition must contain the first component. A component and a second component, containing one or both components of the third component and the fourth component at the same time. The D-ribose and amino acid based composition does not contain either caffeine or guarana extract. The composition based on D-ribose and amino acids has the effects of rapidly replenishing physical strength and anti-fatigue, and is suitable for people who need to replenish physical strength and anti-fatigue quickly.

D-核糖是含五个碳原子的单糖,是生物体内遗传物质—核糖核酸 (RNA)的重要组成物质,与腺苷酸的形成和三磷酸腺苷(ATP)的再生有密切关系。研究证实,D-核糖是肌肉合成能量物质ATP的重要原料,具有缓解疲劳、增强机体能量、改善心脏缺血,提升心脏功能、缓解肌肉酸痛等优势。D-ribose is a monosaccharide containing five carbon atoms. It is an important component of ribonucleic acid (RNA), the genetic material in organisms, and is closely related to the formation of adenosine and the regeneration of adenosine triphosphate (ATP). Studies have confirmed that D-ribose is an important raw material for muscle synthesis of energy substance ATP. It has the advantages of relieving fatigue, enhancing body energy, improving cardiac ischemia, improving cardiac function, and relieving muscle soreness.

氨基酸是构成生命的最基本物质,是蛋白质的组成单位,人体内的氨基酸一共约有20种,成人的八种必需氨基酸包括赖氨酸、苯丙氨酸、蛋氨酸、苏氨酸、异亮氨酸、亮氨酸、缬氨酸以及色氨酸。除成人的8种之外,婴儿必需氨基酸共有9种,除上述八种外,还包括组氨酸。氨基酸的作用与功效包括增强人体的免疫力、合成组织蛋白质、为机体提供能量、使注意力集中、促进睡眠、帮助分解脂肪和预防心脑血管疾病、肝脏疾病和肾脏疾病等。Amino acids are the most basic substances that constitute life and are the constituent units of proteins. There are about 20 kinds of amino acids in the human body. The eight essential amino acids for adults include lysine, phenylalanine, methionine, threonine, and isoleucine. acid, leucine, valine and tryptophan. In addition to the 8 for adults, there are 9 essential amino acids for infants, including histidine in addition to the above-mentioned eight. The role and efficacy of amino acids include enhancing the body's immunity, synthesizing tissue proteins, providing energy for the body, focusing attention, promoting sleep, helping to break down fat and preventing cardiovascular and cerebrovascular diseases, liver diseases and kidney diseases.

牛磺酸又称β-氨基乙磺酸,是一种含硫的非蛋白氨基酸,具有多种有益于人体的生理功能,但人体合成的牛磺酸很少,主要依靠摄取食物中的牛磺酸来满足机体需要。Taurine, also known as β-aminoethanesulfonic acid, is a sulfur-containing non-protein amino acid with a variety of physiological functions beneficial to the human body. acid to meet the body's needs.

麦芽糖(maltose)是由两个葡萄糖单位经由α-1,4糖苷键连接而成的二糖,又称为麦芽二糖。麦芽糖的功效与作用包括:补充机体所需的碳源和能量、维持肠道健康、预防高血压和高血脂以及动脉硬化、保护肝脏和预防肝硬化等。Maltose is a disaccharide composed of two glucose units linked by α-1,4 glycosidic bonds, also known as maltobiose. The efficacy and role of maltose include: supplementing the carbon source and energy required by the body, maintaining intestinal health, preventing hypertension and hyperlipidemia, arteriosclerosis, protecting the liver and preventing liver cirrhosis, etc.

茶是众所周知的健康饮品,在16世纪就被欧洲精英阶层称为“神奇的东方树叶”。茶叶提取物种还有诸多有益成分,例如茶多酚(具有抗氧化、消除氧自由基、抗炎、降低心血管病发病几率、降血脂、减少体脂形成、抗菌、改变肠道菌群生态等多项功效)、茶色素(主要包括叶绿素、β-胡萝卜素等,具有延缓衰老以及美容等作用)、茶氨酸(能提高大脑功能,增强记忆力和学习能力,对阿尔海默病、帕金森病及自主神经功能紊乱都有预防作用)、茶多糖(具有抗辐射、增加白细胞数量、提高免疫力的作用,还能降血糖、γ-氨基丁酸(主要功效是扩张血管使血压下降,故可辅助治疗高血压,它还能改善大脑血液循环,增强脑细胞的代谢能力)。Tea is a well-known health drink, known as "the magical oriental leaf" by the European elite in the 16th century. There are also many beneficial components in tea extract species, such as tea polyphenols (antioxidant, eliminating oxygen free radicals, anti-inflammatory, reducing the risk of cardiovascular disease, lowering blood lipids, reducing body fat formation, antibacterial, and changing intestinal flora ecology, etc. Multiple effects), tea pigments (mainly including chlorophyll, β-carotene, etc., which can delay aging and beautify), theanine (can improve brain function, enhance memory and learning ability, and are effective for Alzheimer's disease, Parkinson's disease, etc.) disease and autonomic dysfunction have preventive effects), tea polysaccharide (with anti-radiation, increase the number of white blood cells, improve immunity, but also lower blood sugar, γ-aminobutyric acid (the main effect is to dilate blood vessels and reduce blood pressure, so It can assist in the treatment of high blood pressure, it can also improve blood circulation in the brain and enhance the metabolic capacity of brain cells).

本发明对上述基于D-核糖和氨基酸的组合物中的原料以及其重量份进行了具有创造性的研究,结果发现上述功能饮料组合物具有迅速恢复体力和抗疲劳方面的多种用途。The present invention has carried out creative research on the raw materials and their weight parts in the above-mentioned D-ribose and amino acid-based composition, and found that the above-mentioned functional drink composition has various purposes in terms of rapid recovery of physical strength and anti-fatigue.

优选地,该基于D-核糖和氨基酸的组合物的主要原料为重量份为1-10 份的第一组分(D-核糖)、重量份为1-10份的第二组分(8种成人必需氨基酸赖氨酸、苯丙氨酸、蛋氨酸、苏氨酸、异亮氨酸、亮氨酸、缬氨酸以及色氨酸之一或者多种组合)、重量份为0-30份的第三组分(第三组分为麦芽糖或牛磺酸之一或者二者组合)、重量份为0-10份的第四组分(茶叶提取物),且第三组分和第四组分不均为0。Preferably, the main raw materials of the composition based on D-ribose and amino acid are 1-10 parts by weight of the first component (D-ribose), and 1-10 parts by weight of the second component (8 kinds) Adult essential amino acids lysine, phenylalanine, methionine, threonine, isoleucine, leucine, valine and tryptophan one or more combinations), 0-30 parts by weight The third component (the third component is one or a combination of maltose or taurine), the fourth component (tea extract) in parts by weight of 0-10 parts, and the third component and the fourth component The score is not equal to 0.

更优选地,该基于D-核糖和氨基酸的组合物的主要原料为重量份为 5-10份的第一组分(D-核糖)、重量份为9-10份的第二组分(8种成人必需氨基酸赖氨酸、苯丙氨酸、蛋氨酸、苏氨酸、异亮氨酸、亮氨酸、缬氨酸以及色氨酸之一或者多种组合)、重量份为0-20份的第三组分(第三组分为麦芽糖或牛磺酸之一或者二者组合)、重量份为0-6份的第四组分(茶叶提取物),且第三组分和第四组分不均为0。More preferably, the main raw materials of the composition based on D-ribose and amino acid are 5-10 parts by weight of the first component (D-ribose), and 9-10 parts by weight of the second component (8 parts by weight). adult essential amino acids lysine, phenylalanine, methionine, threonine, isoleucine, leucine, valine and tryptophan one or more combinations), the weight part is 0-20 parts The third component (the third component is one of maltose or taurine or a combination of the two), the fourth component (tea extract) in parts by weight is 0-6 parts, and the third component and the fourth component are The components are not all 0.

更进一步地,该基于D-核糖和氨基酸的组合物的主要原料为重量份为 8-10份的第一组分(D-核糖)、重量份为9-10份的第二组分(8种成人必需氨基酸赖氨酸、苯丙氨酸、蛋氨酸、苏氨酸、异亮氨酸、亮氨酸、缬氨酸以及色氨酸之一或者多种组合)、重量份为5-6份的第四组分(茶叶提取物)。Further, the main raw materials of the composition based on D-ribose and amino acid are 8-10 parts by weight of the first component (D-ribose), and 9-10 parts by weight of the second component (8 parts by weight). adult essential amino acids lysine, phenylalanine, methionine, threonine, isoleucine, leucine, valine and tryptophan one or more combinations), the weight part is 5-6 parts The fourth component (tea extract).

更进一步地,该基于D-核糖和氨基酸的组合物的主要原料为重量份为 8-10份的第一组分(D-核糖)、重量份为9-10份的第二组分(8种成人必需氨基酸赖氨酸、苯丙氨酸、蛋氨酸、苏氨酸、异亮氨酸、亮氨酸、缬氨酸以及色氨酸之一或者多种组合)、重量份为8-20份的第三组分(第三组分为麦芽糖或牛磺酸之一或者二者组合)。Further, the main raw materials of the composition based on D-ribose and amino acid are 8-10 parts by weight of the first component (D-ribose), and 9-10 parts by weight of the second component (8 parts by weight). adult essential amino acids lysine, phenylalanine, methionine, threonine, isoleucine, leucine, valine and tryptophan one or more combinations), the weight part is 8-20 parts The third component (the third component is one of maltose or taurine or a combination of the two).

更进一步地,该基于D-核糖和氨基酸的组合物的主要原料为重量份为 8-10份的第一组分(D-核糖)、重量份为9-10份的第二组分(8种成人必需氨基酸赖氨酸、苯丙氨酸、蛋氨酸、苏氨酸、异亮氨酸、亮氨酸、缬氨酸以及色氨酸之一或者多种组合)、重量份为8-20份的第三组分(第三组分为麦芽糖或牛磺酸之一或者二者组合)、重量份为5-6份的第四组分(茶叶提取物)。Further, the main raw materials of the composition based on D-ribose and amino acid are 8-10 parts by weight of the first component (D-ribose), and 9-10 parts by weight of the second component (8 parts by weight). adult essential amino acids lysine, phenylalanine, methionine, threonine, isoleucine, leucine, valine and tryptophan one or more combinations), the weight part is 8-20 parts The third component (the third component is one of maltose or taurine or a combination of the two), and the fourth component (tea extract) in parts by weight of 5-6 parts.

本发明的第二方面提供上述基于D-核糖和氨基酸的组合物在制备具有迅速补充体力和抗疲劳作用的产品中的应用。The second aspect of the present invention provides the use of the above-mentioned D-ribose and amino acid-based composition in the preparation of a product with rapid stamina replenishment and anti-fatigue effects.

本发明的第三方面提供一种功能饮料,包括本发明第一方面提供的基于D-核糖和氨基酸的组合物。A third aspect of the present invention provides a functional drink, comprising the D-ribose and amino acid-based composition provided by the first aspect of the present invention.

优选地,该功能饮料中,第一组分的浓度为0.01g/L~2g/L,例如可以为 0.01g/L、0.1g/L、0.5g/L、1g/L、1.5g/L、2g/L。Preferably, in the functional drink, the concentration of the first component is 0.01g/L~2g/L, for example, it can be 0.01g/L, 0.1g/L, 0.5g/L, 1g/L, 1.5g/L , 2g/L.

优选地,该功能饮料包含除含有上述基于D-核糖和氨基酸的组合物外,还包括水、其它食品添加剂与辅料,本发明对此不作限制。Preferably, the functional drink includes, in addition to the above-mentioned composition based on D-ribose and amino acids, water, other food additives and auxiliary materials, which are not limited in the present invention.

实施例1:功能饮料YL-1的制备Example 1: Preparation of functional drink YL-1

取以下重量的原料:D-核糖100g、赖氨酸90g、麦芽糖200g、茶叶提取物50g,加去离子水溶解并稀释至100L,分装为200瓶(每瓶500毫升),得功能饮料YL-1。Take the following raw materials: 100g of D-ribose, 90g of lysine, 200g of maltose, and 50g of tea extract, add deionized water to dissolve and dilute to 100L, and divide into 200 bottles (500ml per bottle) to obtain functional drink YL -1.

实施例2:功能饮料YL-2的制备Example 2: Preparation of functional drink YL-2

取以下重量的原料:D-核糖100g、苯丙氨酸90g、牛磺酸80g、茶叶提取物50g,加去离子水溶解并稀释至100L,分装为200瓶(每瓶500毫升),得功能饮料YL-2。Take the following raw materials: 100 g of D-ribose, 90 g of phenylalanine, 80 g of taurine, and 50 g of tea extract, add deionized water to dissolve and dilute to 100 L, and divide into 200 bottles (500 ml per bottle) to obtain Functional drink YL-2.

实施例3:功能饮料YL-3的制备Example 3: Preparation of functional drink YL-3

取以下重量的原料:D-核糖50g、蛋氨酸90g、麦芽糖200g、茶叶提取物50g,加去离子水溶解并稀释至100L,分装为200瓶(每瓶500毫升),得功能饮料YL-3。Take the following raw materials: D-ribose 50g, methionine 90g, maltose 200g, tea extract 50g, add deionized water to dissolve and dilute to 100L, and pack into 200 bottles (500ml per bottle) to obtain functional drink YL-3 .

实施例4:功能饮料YL-4的制备Example 4: Preparation of functional drink YL-4

取以下重量的原料:D-核糖100g、苏氨酸30g、异亮氨酸30g、亮氨酸30g、麦芽糖150g、茶叶提取物50g,加去离子水溶解并稀释至100L,分装为200瓶(每瓶500毫升),得功能饮料YL-4。Take the following raw materials: D-ribose 100g, threonine 30g, isoleucine 30g, leucine 30g, maltose 150g, tea extract 50g, add deionized water to dissolve and dilute to 100L, and pack into 200 bottles (500ml per bottle), get functional drink YL-4.

实施例5:功能饮料YL-5的制备Example 5: Preparation of functional drink YL-5

取以下重量的原料:D-核糖80g、赖氨酸40g、缬氨酸30g、色氨酸 30g、茶叶提取物60g,加去离子水溶解并稀释至100L,分装为200瓶(每瓶500毫升),得功能饮料YL-5。Take the following raw materials: D-ribose 80g, lysine 40g, valine 30g, tryptophan 30g, tea extract 60g, add deionized water to dissolve and dilute to 100L, and divide into 200 bottles (500 ml) to get the energy drink YL-5.

实施例6:功能饮料YL-6的制备Example 6: Preparation of functional drink YL-6

取以下重量的原料:D-核糖100g、赖氨酸90g、麦芽糖100g、牛磺酸80g、茶叶提取物50g,加去离子水溶解并稀释至100L,分装为200 瓶(每瓶500毫升),得功能饮料YL-6。Take the following raw materials: D-ribose 100g, lysine 90g, maltose 100g, taurine 80g, tea extract 50g, add deionized water to dissolve and dilute to 100L, and pack into 200 bottles (500ml per bottle) , get the energy drink YL-6.

实施例7:功能饮料YL-7的制备Example 7: Preparation of functional drink YL-7

取以下重量的原料:D-核糖100g、赖氨酸50g、苏氨酸50g、麦芽糖 100g、牛磺酸80g,加去离子水溶解并稀释至100L,分装为200瓶(每瓶500毫升),得功能饮料YL-7。Take the following raw materials: D-ribose 100g, lysine 50g, threonine 50g, maltose 100g, taurine 80g, add deionized water to dissolve and dilute to 100L, and pack into 200 bottles (500ml per bottle) , get the energy drink YL-7.

试验组:小鼠游泳实验Experimental group: mouse swimming experiment

选用昆明种小鼠,体重18-22g,随机平均分为20个组(A-T组),A-G 组依次用实施例1-7制备的功能饮料YL-1~YL-7灌胃,H组为空白对照组灌胃等量生理盐水,I-T组依次用不同单组分、多组分功能饮料灌胃。每只小鼠0.1ml,每天上、下午各1次,共3天。于最后1次灌胃后30min时,在小鼠尾根部缠上相当干其体重7.5%的铅丝,置干水温为25℃左右的水箱中游泳,记录小鼠自游泳开始至沉落水底死亡的时间,以秒作为时间单位进行统计处理,结果见表1。Kunming mice, weighing 18-22g, were randomly divided into 20 groups (A-T groups) on average. Groups A-G were given the functional drinks YL-1~YL-7 prepared in Examples 1-7 by gavage in turn, and group H was blank. The control group was given the same amount of normal saline, and the I-T group was given different single-component and multi-component functional drinks. 0.1ml per mouse, once a day in the morning and in the afternoon, for a total of 3 days. At 30 min after the last gavage, a lead wire of 7.5% of its body weight was wrapped around the base of the tail of the mice, and the mice were placed in a water tank with a dry water temperature of about 25 °C to swim, and the mice were recorded from the start of swimming to the death of the submerged water. time, with seconds as the time unit for statistical processing, the results are shown in Table 1.

表1各组小鼠在灌胃后的游泳时间对照表Table 1 Comparison of swimming time of mice in each group after gavage

Figure BDA0003642554650000071
Figure BDA0003642554650000071

Figure BDA0003642554650000081
Figure BDA0003642554650000081

从表1数据可以看出,与H组、单组分的I-M组和双组份的N-T组相比,A-G组用本发明制备的功能饮料灌胃后小鼠的表现要出色得多,说明本发明实施例中的三组分和四组分配方能起到明显的协同增效作用,可见本发明所制备的功能饮料确实起到迅速补充体力和抵抗疲劳的显著效果;同时,第三组分同时含有牛磺酸和麦芽糖时,更有利于发挥其协同作用,显著提高抗疲劳效果。As can be seen from the data in Table 1, compared with the H group, the single-component I-M group and the two-component N-T group, the mice in the A-G group after gavage with the functional drink prepared by the present invention performed much better. The three-component and four-component formulas in the examples of the present invention can play an obvious synergistic effect, and it can be seen that the functional beverage prepared by the present invention has a remarkable effect of quickly replenishing physical strength and resisting fatigue; at the same time, the third group When it contains taurine and maltose at the same time, it is more conducive to exert its synergistic effect and significantly improve the anti-fatigue effect.

以上所述本发明的具体实施方式,并不构成对本发明保护范围的限定。任何根据本发明的技术构思所做出的各种其他相应的改变与变形,均应包含在本发明权利要求的保护范围内。The specific embodiments of the present invention described above do not limit the protection scope of the present invention. Any other corresponding changes and modifications made according to the technical concept of the present invention shall be included in the protection scope of the claims of the present invention.

Claims (10)

1.一种基于D-核糖和氨基酸的组合物,其特征在于,所述基于D-核糖和氨基酸的组合物包括:第一组分、第二组分、第三组分、第四组分;其中,第一组分为D-核糖,第二组分为赖氨酸、苯丙氨酸、蛋氨酸、苏氨酸、异亮氨酸、亮氨酸、缬氨酸或色氨酸之一或者多种组合,第三组分为麦芽糖或牛磺酸之一或者二者组合,第四组分为茶叶提取物;所述基于D-核糖和氨基酸的组合物必含有第一组分和第二组分,同时含有第三组分和第四组分的一种或两种组分,且不含有咖啡因或瓜拉纳提取物中的任意一种。1. a composition based on D-ribose and amino acid, is characterized in that, described composition based on D-ribose and amino acid comprises: the first component, the second component, the third component, the fourth component wherein, the first component is D-ribose, and the second component is one of lysine, phenylalanine, methionine, threonine, isoleucine, leucine, valine or tryptophan Or multiple combinations, the third component is one or a combination of maltose or taurine, and the fourth component is tea extract; the D-ribose and amino acid-based composition must contain the first component and the first component. Two components, containing one or both of the third component and the fourth component at the same time, and not containing either caffeine or guarana extract. 2.根据权利要求1所述基于D-核糖和氨基酸的组合物,其特征在于,所述基于D-核糖和氨基酸的组合物包括:重量份为1-10份的第一组分、重量份为1-10份的第二组分、重量份为0-30份的第三组分、重量份为0-10份的第四组分,且第三组分和第四组分不均为0。2. the composition based on D-ribose and amino acid according to claim 1, is characterized in that, described composition based on D-ribose and amino acid comprises: the first component of 1-10 parts by weight, part by weight 1-10 parts of the second component, 0-30 parts by weight of the third component, 0-10 parts by weight of the fourth component, and the third component and the fourth component are not 0. 3.根据权利要求1所述基于D-核糖和氨基酸的组合物,其特征在于,所述基于D-核糖和氨基酸的组合物包括:重量份为5-10份的第一组分、重量份为9-10份的第二组分、重量份为0-20份的第三组分、重量份为0-6份的第四组分,且第三组分和第四组分不均为0。3. the composition based on D-ribose and amino acid according to claim 1, is characterized in that, described composition based on D-ribose and amino acid comprises: weight part is 5-10 part of the first component, weight part It is 9-10 parts of the second component, 0-20 parts by weight of the third component, and 0-6 parts by weight of the fourth component, and the third component and the fourth component are not both 0. 4.根据权利要求1所述基于D-核糖和氨基酸的组合物,其特征在于,所述基于D-核糖和氨基酸的组合物包括:重量份为8-10份的第一组分、重量份为9-10份的第二组分、重量份为5-6份的第四组分。4. the composition based on D-ribose and amino acid according to claim 1, is characterized in that, described composition based on D-ribose and amino acid comprises: weight part is 8-10 parts of the first component, weight part 9-10 parts by weight of the second component, and 5-6 parts by weight of the fourth component. 5.根据权利要求1所述基于D-核糖和氨基酸的组合物,其特征在于,所述基于D-核糖和氨基酸的组合物包括:重量份为8-10份的第一组分、重量份为9-10份的第二组分、重量份为8-20份的第三组分。5. the composition based on D-ribose and amino acid according to claim 1, is characterized in that, described composition based on D-ribose and amino acid comprises: weight part is 8-10 parts of the first component, weight part 9-10 parts by weight of the second component, and 8-20 parts by weight of the third component. 6.根据权利要求1所述基于D-核糖和氨基酸的组合物,其特征在于,所述基于D-核糖和氨基酸的组合物包括:重量份为8-10份的第一组分、重量份为9-10份的第二组分、重量份为8-20份的第三组分、重量份为5-6份的第四组分。6. the composition based on D-ribose and amino acid according to claim 1, is characterized in that, described composition based on D-ribose and amino acid comprises: the first component of 8-10 parts by weight, the part by weight 9-10 parts by weight of the second component, 8-20 parts by weight of the third component, and 5-6 parts by weight of the fourth component. 7.如权利要求1~6中任一项所述基于D-核糖和氨基酸的组合物在制备具有迅速补充体力和抗疲劳作用的产品中的应用。7. The use of the D-ribose and amino acid-based composition according to any one of claims 1 to 6 in the preparation of a product with rapid stamina replenishment and anti-fatigue effects. 8.一种功能饮料,其特征在于,所述功能饮料包括权利要求1~6中任一项所述基于D-核糖和氨基酸的组合物。8 . A functional drink, characterized in that, the functional drink comprises the composition based on D-ribose and amino acids according to any one of claims 1 to 6 . 9.根据权利要求8所述功能饮料,其特征在于,所述功能饮料中,第一组分的浓度为0.01g/L~2g/L。9 . The functional beverage according to claim 8 , wherein, in the functional beverage, the concentration of the first component is 0.01 g/L to 2 g/L. 10 . 10.根据权利要求8所述功能饮料,其特征在于,所述功能饮料还包括:水、其它食品添加剂与辅料。10 . The functional beverage according to claim 8 , wherein the functional beverage further comprises: water, other food additives and auxiliary materials. 11 .
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