CN114796839B - A microneedle inserter based on gravity loading - Google Patents

Abstract

The microneedle needle feeder based on gravity loading comprises a vertical shell with a hollow inner cavity, wherein the upper end of the vertical shell is in threaded connection with a machine body which can be screwed in or out relative to the vertical shell, and the inner cavity of the machine body is communicated with the inner cavity of the vertical shell; the top of the machine body is provided with a push switch, and the inner cavity of the machine body is provided with a power supply and an electromagnet which are arranged up and down; the inner cavity of the vertical shell is divided into an upper cavity and a lower cavity by the diaphragm plate, and the upper cavity of the pressure head is communicated with the inner cavity of the shell; the upper cavity of the pressure head is internally provided with a push rod tail, the push rod tail is provided with a connecting rod which downwards penetrates through the through hole, the connecting rod is connected with the head of the push rod, and the bottom surface of the head of the push rod is provided with an elastic gasket which can be attached to the outline of the skin and can press the microneedle patch into the skin. The invention has controllable force, can adapt to the radian of skin and can avoid manual needle insertion.

Description

A microneedle inserter based on gravity loading

Technical Field

The present invention relates to the technical field of medical devices, and in particular to a microneedle inserter based on gravity loading.

Background technique

Microneedles are tiny in size and can deliver drugs through the skin without touching the subcutaneous nerves, so they can achieve the purpose of painless transdermal drug delivery. In order to deliver enough drugs to the skin, people often use microneedle patches as carriers for painless transdermal drug delivery.

Microneedles are usually distributed on the microneedle patch in a certain way. In addition, the size of the microneedles is very small, so the microneedle patch needs to penetrate the skin with a certain force and speed, otherwise the microneedles on the microneedle patch are prone to breakage or bending, which will affect the transdermal drug delivery effect of the microneedle patch.

Although the force and time of the current microneedle inserters are controllable, they mostly use manual labor to insert the needles, and almost do not consider the impact of uneven force on the microneedle patch caused by the curvature and contour of the skin. Therefore, it is necessary to develop a microneedle inserter with controllable force, adaptable to the curvature of the skin, and able to avoid manual insertion.

Summary of the invention

In order to overcome the above problems, the present invention provides a microneedle inserter based on gravity loading.

The technical solution adopted by the present invention is: a microneedle inserter based on gravity loading, comprising a vertical shell with a hollow inner cavity, the upper end of the vertical shell is threadedly connected to a body that can be screwed in or out relative to the vertical shell, and the inner cavity of the body is connected to the inner cavity of the vertical shell; a push switch is provided on the top of the body, an indicator light is provided on the outer wall of the body, a power supply and an electromagnet arranged up and down are provided in the inner cavity of the body, a magnetic coil is wound around the electromagnet, and the power supply is connected in series with the electromagnet, the indicator light, and the push switch in sequence;

A slider with a certain weight is slidably connected in the inner cavity of the vertical shell and located below the body, and the slider is made of magnetic material; the inner wall of the inner cavity of the vertical shell is provided with a plurality of slide grooves extending in the vertical direction at intervals along the circumferential direction, and the outer wall of the slider is provided with grooves at positions corresponding to the slide grooves, and a roller slidably connected to the slide groove is provided in the groove;

A pressure head is connected to the lower end of the vertical shell, and a diaphragm is provided in the inner cavity of the pressure head, and a through hole is provided in the center of the diaphragm; the diaphragm divides the inner cavity of the pressure head into an upper cavity and a lower cavity, and the upper cavity of the pressure head is connected with the inner cavity of the shell; a push rod tail is provided in the upper cavity of the pressure head, and the push rod tail is in the shape of a circular plate; a connecting rod is provided at the center of the bottom surface of the push rod tail, and the connecting rod passes through the through hole of the diaphragm and extends into the lower cavity of the pressure head and is connected to the push rod head, and a spring is sleeved on the connecting rod and located between the upper surface of the diaphragm and the lower surface of the push rod tail; the push rod head is in the shape of a circular plate, and an elastic gasket is provided on the bottom surface of the push rod head, and the elastic gasket is elastic, and the elastic gasket can adapt to the skin contour and press the microneedle patch into the skin;

When the electromagnet is energized, it generates magnetic force, attracting the slider to lift upward. At this time, the spring is in a natural state, the tail of the push rod is lifted, and the head of the push rod is retracted in the lower cavity of the pressure head; when the electromagnet is powered off, the magnetic force disappears, and the slider moves downward under the action of gravity and falls on the tail of the push rod. The tail of the push rod is pressed down, the spring is in a compressed state, and the head of the push rod extends out of the pressure head to press the microneedle patch into the skin.

Furthermore, the number of the slide grooves is four, and the four slide grooves are arranged at intervals along the circumferential direction on the inner wall of the inner cavity of the vertical shell, and the upper and lower ends of the slide grooves extend to the top surface and the bottom surface of the shell respectively.

Furthermore, the inner wall of the inner cavity of the vertical shell is provided with an internal thread, and the outer wall of the body is provided with an external thread matching the internal thread.

The beneficial effects of the present invention are:

1. The outer wall of the body is connected to the inner thread of the inner wall of the shell through an external thread, and a scale line of the force value is marked on the outer wall of the body, so the body can control the feed amount into the shell through the thread, which can change the displacement stroke of the slider, thereby changing the force of the push rod pressing against the microneedle patch;

2. The electromagnet can fix the slider when power is on. When power is off, the electromagnet will lose its electromagnetic force, and the slider will be impacted downward along the slide groove inside the shell by gravity, transferring the kinetic energy obtained by gravity to the tail of the push rod, which compresses the spring to move outside the pressure head, so that the elastic gasket at the head of the push rod presses the microneedle patch into the skin surface, which can adapt to the curvature of the skin and avoid manual needle insertion.

BRIEF DESCRIPTION OF THE DRAWINGS

Fig. 1 is a cross-sectional view of the present invention before use.

FIG. 2 is a cross-sectional view of the present invention in use.

FIG. 3 is a cross-sectional view of the present invention after use.

FIG. 4 is an exploded view of the present invention.

Detailed ways

The technical solution of the present invention will be described clearly and completely below in conjunction with the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

In the description of the present invention, it should be noted that the orientations or positional relationships indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. are based on the orientations or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance.

In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected" and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

Referring to the accompanying drawings, a microneedle inserter based on gravity loading includes a vertical shell 12 with a hollow inner cavity, and the vertical shell 12 is cylindrical as a whole; the upper end of the vertical shell 12 is threadedly connected to a body 5 that can be screwed in or out relative to the vertical shell 12, and the inner cavity of the body 5 is connected to the inner cavity of the vertical shell 12; the inner wall of the inner cavity of the vertical shell 12 is provided with an internal thread, and the outer wall of the body 5 is provided with an external thread that matches the internal thread.

A push switch 8 is provided on the top of the body 5, an indicator light 7 is provided on the outer wall of the body 5, a power supply 9 and an electromagnet 6 are arranged up and down in the inner cavity of the body 5, a magnetic coil 61 is wound around the electromagnet 6, and the power supply 9 is connected in series with the electromagnet 6, the indicator light 7, and the push switch 8 in sequence; when the push switch 8 is pressed, the electromagnet 6 is in a power-on state, and the indicator light 7 lights up green; when the push switch 8 is pressed again, the electromagnet 6 is in a power-off state, and the electromagnet 6 will lose the electromagnetic force, and the indicator light 7 will also be extinguished; it also includes a control circuit and a power indicator light 7, the control circuit is electrically connected to the power supply 9 and the power indicator light 7 respectively, and when the power of the power supply 9 is insufficient or before being fully charged, the control circuit will send a red light instruction to the power indicator light 7;

A slider 10 is slidably connected in the inner cavity of the vertical shell 12 and located below the body 5. The slider 10 is a magnetic column with a certain weight. The inner wall of the inner cavity of the vertical shell 12 is provided with four slide grooves extending in the vertical direction at intervals along the circumferential direction. The four slide grooves are arranged on the internal threads of the inner wall of the inner cavity of the vertical shell 12 at intervals along the circumferential direction. The upper and lower ends of the slide groove extend to the top and bottom surfaces of the shell 12 respectively. The slide groove does not affect the meshing of the internal thread and the external thread. A groove is provided on the outer wall of the slider 10 at a position corresponding to the slide groove, and a roller 11 slidably connected to the slide groove is provided in the groove.

A pressure head 1 is connected to the lower end of the vertical shell 12, and a transverse partition is provided in the inner cavity of the pressure head 1, and a through hole is provided in the center of the transverse partition; the transverse partition divides the inner cavity of the pressure head 1 into an upper cavity and a lower cavity, and the upper cavity of the pressure head 1 is connected with the inner cavity of the shell 12; a push rod tail 2 is provided in the upper cavity of the pressure head 1, and the push rod tail 2 is in the shape of a circular plate; a connecting rod is provided in the center of the bottom surface of the push rod tail 2, and the connecting rod passes through the through hole of the transverse partition and extends into the lower cavity of the pressure head 1 and is connected to the push rod head 21, and the connecting rod is connected to the push rod head 21. A spring 4 is sleeved on the connecting rod and located between the upper surface of the diaphragm and the lower surface of the push rod tail 2; the push rod head 21 is in the shape of a circular plate, and the bottom surface of the push rod head 21 is provided with an elastic gasket 3 that can adapt to the skin contour and press the microneedle patch into the skin; under the elastic force of the spring 4, the push rod head 21 is often contracted in the lower cavity of the pressure head 1, and only when the push rod tail 2 is subjected to a sufficiently large external force, the push rod head 21 can move to the outside of the pressure head 1, thereby pressing the microneedle patch into the skin surface.

When the electromagnet 6 is energized, it generates magnetic force, attracting the slider 10 to lift upward. At this time, the spring 4 is in a natural state, the tail 2 of the push rod is lifted, and the head 21 of the push rod is contracted in the lower cavity of the pressure head 1; when the electromagnet 6 is powered off, the magnetic force disappears, and the slider 10 moves downward under the action of gravity and falls on the tail 2 of the push rod. The tail 2 of the push rod is pressed down, the spring 4 is in a compressed state, and the head 21 of the push rod extends out of the pressure head 1 to press the microneedle patch into the skin.

In this embodiment, the microneedle patch needs to be attached to the target skin before use, and the feeding amount of the body 5 into the housing 12 is adjusted to the desired value;

When in use, the first step is to press the push switch 8 to energize the electromagnet 6 to fix the slider 10. At this time, the indicator light 7 lights up green, and then the pressure head 1 is placed on the skin, and the microneedle patch is in the center of the pressure head 1. Due to the action of the spring 4 on the tail 2 of the push rod, the head 21 of the push rod is contracted in the lower cavity of the pressure head 1. At this time, the microneedle patch is not subjected to force;

In the second step, after the pressure head 1 is in stable contact with the skin, the push switch 8 is pressed again. At this time, the power supply of the electromagnet 6 is cut off and the electromagnetic force is lost. The slider 10 slides downward along the slide groove inside the shell 12 by relying on the roller 11 due to the action of gravity, and the kinetic energy generated by gravity is transmitted to the tail 2 of the push rod. The tail 2 of the push rod compresses the spring 4 and transmits the kinetic energy to the head 21 of the push rod. At this time, the head 21 of the push rod moves to the outside of the pressure head 1, relies on the elastic gasket 3 to fit the skin contour and press the microneedle patch into the skin surface.

If the physical properties of the skin change, the force required for the microneedle patch to be inserted will also change. In order to adapt to skins with different physical properties, the displacement stroke of the slider 10 can be changed by adjusting the feed amount of the body 5 into the housing 12, thereby achieving the effect of changing the insertion force of the ejector head 21.

After the microneedle inserter is used, the body 5 can be completely retracted into the housing 12, thereby achieving the effects of protecting the body 5 and saving space.

The contents described in the embodiments of this specification are merely an enumeration of the implementation forms of the inventive concept. The protection scope of the present invention should not be regarded as limited to the specific forms described in the embodiments. The protection scope of the present invention also extends to equivalent technical means that can be conceived by those skilled in the art based on the inventive concept.

Claims (3)

1. A microneedle injector based on gravity loading, characterized in that: the device comprises a vertical shell (12) with a hollow inner cavity, wherein the upper end of the vertical shell (12) is in threaded connection with a machine body (5) which can be screwed in or out relative to the vertical shell (12), and the inner cavity of the machine body (5) is communicated with the inner cavity of the vertical shell (12); the top of the machine body (5) is provided with a push switch (8), the outer side wall of the machine body (5) is provided with an indicator lamp (7), the inner cavity of the machine body (5) is provided with a power supply (9) and an electromagnet (6) which are arranged up and down, a magnetic coil (61) is wound around the electromagnet (6), and the power supply (9) is sequentially connected with the electromagnet (6), the indicator lamp (7) and the push switch (8) in series;

A sliding block (10) with a certain weight is connected in the inner cavity of the vertical shell (12) and positioned below the machine body (5) in a sliding way, and the sliding block (10) is made of a magnetic material; the inner wall of the inner cavity of the vertical shell (12) is provided with a plurality of sliding grooves extending along the vertical direction at intervals along the circumferential direction, the outer wall of the sliding block (10) is provided with a groove at the position corresponding to the sliding groove, and a roller (11) in sliding connection with the sliding groove is arranged in the groove;

The lower end of the vertical shell (12) is connected with a pressure head (1), the inner cavity of the pressure head (1) is provided with a diaphragm, and the center of the diaphragm is provided with a through hole; the diaphragm plate divides the inner cavity of the pressure head (1) into an upper cavity and a lower cavity, and the upper cavity of the pressure head (1) is communicated with the inner cavity of the shell (12); a push rod tail (2) is arranged in the upper cavity of the pressure head (1), and the push rod tail (2) is in a circular plate shape; the center of the bottom surface of the ejector rod tail part (2) is provided with a connecting rod, the connecting rod penetrates through a through hole of the diaphragm plate to extend into a lower cavity of the pressure head (1) and is connected with the ejector rod head (21), and a spring (4) is sleeved on the connecting rod and positioned between the upper surface of the diaphragm plate and the lower surface of the ejector rod tail part (2); the ejector rod head (21) is in a circular plate shape, the elastic gasket (3) is arranged on the bottom surface of the ejector rod head (21), and the elastic gasket (3) has elasticity and can adapt to the skin contour and press the microneedle patch into the skin;

When the electromagnet (6) is electrified, magnetic force is generated to attract the sliding block (10) to lift upwards, the spring (4) is in a natural state, the tail part (2) of the ejector rod is jacked, and the head part (21) of the ejector rod is contracted in the lower cavity of the pressure head (1); when the electromagnet (6) is powered off, the magnetic force disappears, the sliding block (10) moves downwards under the action of gravity and falls on the ejector rod tail (2), the ejector rod tail (2) is pressed down, the spring (4) is in a compressed state, and the ejector rod head (21) stretches out of the pressure head (1) to press the microneedle patch into the skin.

2. A gravity-based microneedle injector according to claim 1, wherein: the number of the sliding grooves is four, the four sliding grooves are arranged on the inner wall of the inner cavity of the vertical shell (12) at intervals along the circumferential direction, and the upper end and the lower end of each sliding groove extend to the top surface and the bottom surface of the shell (12) respectively.

3. A gravity-based microneedle injector according to claim 1, wherein: the inner wall of the inner cavity of the vertical shell (12) is provided with an internal thread, and the outer wall of the machine body (5) is provided with an external thread matched with the internal thread.