CN114767590A - A kind of cosmetic liquid for removing scars and acne marks and preparation method and application thereof - Google Patents

Abstract

The invention belongs to the field of cosmetic preparations, and particularly relates to scar and acne mark removing cosmetic liquid as well as a preparation method and application thereof. The scar-removing acne-mark-removing beauty lotion comprises the following raw materials: centella asiatica extract, honeysuckle flower extract, trumpet creeper flower extract, alanyl glutamine, propylene diglycerol acrylate/acrylic acid copolymer, PVM/MA copolymer, glycerin, methyl hydroxybenzoate, propyl hydroxybenzoate and deionized water. The scar-removing acne mark-removing beauty lotion provided by the invention can effectively resist inflammation, inhibit acne scar formation and hyperplasia, soften formed old acne marks, repair redness and acne mark pigmentation and have the function of skin water locking.

Description

A kind of cosmetic liquid for removing scars and acne marks and preparation method and application thereof

technical field

The invention relates to the technical field of traditional Chinese medicines, in particular to a cosmetic liquid for removing scars and acne marks and a preparation method and application thereof.

Background technique

Acne occurs on the face, chest and back, and is a peripilitis skin disease caused by excessive sebum secretion, blockage of pilosebaceous ducts and Propionibacterium acnes. In addition to children, about 80% to 90% of the population suffer from this disease or have suffered from acne. Inflammatory healing often leaves scars, mainly including pigmentation and depression scars. Internationally, depression scars are divided into box car type scars, rolling type scars and ice pick type scars. Facial acne scars will affect people's psychology. Many people feel inferior because of acne scars, and many people lose the right to freely choose a job and choose a marriage. Because of this, it is particularly important to actively treat acne scars.

At present, the traditional Chinese medicine for treating acne scars is mainly asiaticoside cream, which is widely used in clinical practice. The needles of the microneedle are very fine, and the rollers are covered with fine needles with a diameter of 0.5mm-2mm. When the needles roll on the skin, the tiny needles are used to puncture the skin many times, creating micropores that penetrate the dermis. Wounds trigger wound healing and growth factor release in the dermis, allowing collagen production and deposition in the upper dermis. Microneedling has a positive effect on acne pitted scars, especially for box-type scars and rolling scars. It can also stimulate facial collagen regeneration, and has a certain full-face beauty and lifting effect. It has been reported clinically that asiaticoside ointment combined with microneedle introduction is applied to acne, but the ointment is thick and greasy in texture, with poor comfort, and there are reactions such as redness, swelling and discomfort on the face after medication. In addition, after microneedling treatment, the skin will be dry and sensitive for a period of time, even active dry lines or local pigmentation or uneven skin tone, and there are problems such as pain and discomfort during the operation.

It is of great significance to develop a cosmetic solution with refreshing texture, effective scar removal and acne scar removal, which can relieve the pain and burning sensation during the microneedling treatment and reduce the side effects of the microneedling treatment.

SUMMARY OF THE INVENTION

In order to overcome the problems existing in the prior art, the purpose of the present invention is to provide a cosmetic liquid for removing scars and acne marks and a preparation method and application thereof.

In order to achieve the above purpose and other related purposes, the present invention adopts the following technical solutions:

The first aspect of the present invention provides a cosmetic solution for removing scars and acne marks, comprising the following components and raw materials: Centella asiatica extract, honeysuckle extract, Ling Xiaohua extract, alanyl glutamine, propylene diglyceryl acrylate /Acrylic copolymer, PVM/MA copolymer, glycerin, methylparaben, propylparaben, and deionized water.

In some preferred embodiments, the weight percentages between the components of the raw materials are: Centella asiatica extract 3.5%-20%, honeysuckle extract 1.5%-10%, Ling Xiaohua extract 1.5%-10%, Aminoacylglutamine 5.0%-20.0%, propylene diglyceryl acrylate/acrylic acid copolymer 15%-55%, PVM/MA copolymer 1.0%-4.0%, glycerin 0.1%-1.0%, methylparaben 0.01% -0.15%, propylparaben 0.01%-0.05%, deionized water 35%-55%.

In some preferred embodiments, the weight percentages between the components of the raw materials are: Centella asiatica extract 5-15%, Honeysuckle flower extract 2-5%, Ling Xiaohua extract 3-5%, Alanyl valley Amino amide 8.0-15.0%, propylene diglyceryl acrylate/acrylic acid copolymer 20-30%, PVM/MA copolymer 2.0-3.0%, glycerin 0.1-0.5%, methylparaben 0.02-0.1%, propylparaben 0.03-0.05%, deionized water 40.0-50.0%.

In some preferred embodiments, the weight percentages between the raw materials of the components are: Centella asiatica extract 10%, Honeysuckle flower extract 3.5%, Ling Xiaohua extract 3.5%, Alanylglutamine 10%, Diglycerol acrylate/acrylic acid copolymer 25%, PVM/MA copolymer 2.0%, glycerin 0.5%, methylparaben 0.05%, propylparaben 0.03%, deionized water 45.42%.

The second aspect of the present invention provides the preparation method of the aforementioned scar removing and acne-removing cosmetic liquid, comprising the following steps:

S1, stirring Centella asiatica extract, honeysuckle flower extract, Ling Xiaohua extract, alanyl glutamine to obtain a first mixture;

S2, with propylene diglycerol acrylate/acrylic acid copolymer, PVM/MA copolymer, glycerol, methylparaben, propylparaben and deionized water, stirring to obtain the second mixture;

S3. The first mixture obtained in step S1 and the second mixture obtained in step S2 are mixed, stirred, and evenly mixed to obtain a cosmetic solution for removing scars and acne marks.

In some preferred embodiments, the stirring speed in step S1 is 60-150 rpm, and the stirring time is 0.5-1 h.

In some preferred embodiments, the stirring speed in step S2 is 100-200 rpm, and the stirring time is 0.5-1 h;

In some preferred embodiments, the stirring speed in step S3 is 100-200 rpm, and the stirring time is 0.5-1 h.

The third aspect of the present invention provides the use of the aforementioned scar-removing and acne-imprint cosmetic liquid in removing scars and acne-imprints.

The fourth aspect of the present invention provides the use of the aforementioned scar-removing and acne-imprint-removing cosmetic solution in the preparation of a medical or cosmetic product for scar repairing or acne-imprint removal.

The fifth aspect of the present invention provides the use of the aforementioned scar-removing and acne-imprinting cosmetic solution for preparing a cosmetic product with any of the following effects: 1) skin depression scar repair; 2) acne-imprint pigmentation reduction; 3) cystic type 4) Inhibit the formation and proliferation of acne scars.

The sixth aspect of the present invention provides the application of the aforementioned scar-removing and acne-printing cosmetic solution in the preparation of a microneedle base solution.

A seventh aspect of the present invention provides a cosmetic product for removing scars and acne marks, including the aforementioned cosmetic solution.

An eighth aspect of the present invention provides a method for using the aforementioned cosmetic liquid, comprising the following steps:

(a) Disinfect the patient's face before use;

(b) Select 0.5mm-1.0mm sterile roller needles, stagger and roll 3-5 times in all directions of the local skin, and apply the aforementioned beauty solution while rolling, until the local skin becomes swollen and the treatment is completed.

The cosmetic solution provided by the invention is combined with the microneedle treatment, which facilitates the introduction of liquid active ingredients, enhances the effect after use, and has better effect than direct application.

Compared with the prior art, the present invention has the following beneficial effects:

1. The cosmetic liquid for removing scars and acne marks provided by the present invention has a synergistic effect between the components, which can inhibit the hyperplasia of scars, reduce hyperpigmentation, anti-inflammatory and analgesic simultaneously, and has the effects of clearing heat and relieving pain, moisturizing and locking water, and is suitable for As a base fluid for microneedling.

2. The cosmetic liquid for removing scars and acne marks provided by the present invention has a significant therapeutic effect on both scars and acne marks, can significantly improve the degree of depression of the patient's scars, improve the skin appearance smoothness, and reduce the pigmentation of acne marks, It can promote cystic acne to reduce swelling and disperse knots, and inhibit acne scar formation and proliferation. It can be used as a microneedle base fluid to reduce the side effects of microneedle therapy. The curative effect is better than asiaticoside ointment, and it has good clinical application value.

Description of drawings

Figure 1 is a photo of the affected area before treatment in typical case 1.

Figure 2 is a photo of the affected area in typical case 1 after treatment.

Figure 3 is a photo of the affected area before treatment in typical case 2.

Figure 4 is a photo of the affected area in typical case 2 after treatment.

Figure 5 is a photo of the affected area before treatment in typical case 3.

Figure 6 is a photo of the affected area after treatment in typical case 3.

Figure 7 is a photo of the affected area before the second treatment in typical case 3.

Figure 8 is a photo of the affected area in typical case 3 after the second treatment.

Detailed ways

The present invention uses Centella asiatica extract as the main component of the cosmetic solution, and the active ingredient asiaticoside has the effects of clearing away heat and dampness, detoxifying and eliminating carbuncle, can inhibit scar hyperplasia, lighten pigmentation, easily penetrate into the skin, and has a refreshing texture; At the same time, honeysuckle extract and Lingxiaohua extract are added. The two synergistically reduce inflammation and redness, calm and relieve, and can effectively relieve the problem of skin redness and sensitivity after rolling acupuncture; Oligopeptide-1 in Alanyl Glutamine (Power Peptide), Oligopeptide-3 is hydrolyzed to generate L-glutamine, which can promote the activity of LXR in the main human keratinocytes and the activation of epidermal lipid synthase, improve the hydration of the skin, and help the skin to resist aging. Water-locking function; polyvinyl formal/methyl acrylate copolymer (PVM/MA copolymer) has a certain lubricating and thickening property, and when used in combination with the above active ingredients, in addition to enhancing the moisturizing property of the cosmetic liquid, the present invention The provided cosmetic liquid can effectively relieve pain and burning sensation in the process when used as the base liquid of microneedle treatment, and relieve the pain of patients.

Propylene diglyceryl acrylate/acrylic acid copolymer: commercially available cosmetic raw materials. Used as a thickening agent, viscosity control agent and moisturizing agent, it can impart fluidity and transparency to beauty serum, mild and non-irritating.

PVM/MA copolymer: commercially available cosmetic raw materials. It is used as antistatic agent, adhesive and emulsion stabilizer in cosmetics.

Glycerin: The chemical name is glycerol. It is a colorless, odorless and sweet viscous liquid with strong water absorption. When applied to the skin, it can moisturise the skin and prevent it from drying out. Glycerin absorbs quickly, and is a good hydrating product for peeling skin in seasons, acne scarred skin, sensitive skin, etc., which can keep the skin soft and elastic, free from dust, weather and other damage and dryness.

Methylparaben: The chemical name is methylparaben, also known as methylparaben or methylparaben, is an organic substance with the chemical formula C ₈ H ₈ O ₃ , white crystalline powder or colorless crystal, It is easily soluble in alcohol, ether and acetone, and very slightly soluble in water, with a boiling point of 270-280 °C. Mainly used as antibacterial preservatives in organic synthesis, food, cosmetics, medicine, and also as feed preservatives.

Propylparaben: The chemical name is propylparaben, also known as propylparaben or propylparaben, is an organic substance with chemical formula C ₁₀ H ₁₂ O ₃ , white crystalline powder, with easy Soluble in alcohol, ether and acetone, slightly soluble in water, boiling point 133℃. Mainly used as antibacterial preservatives in organic synthesis, food, cosmetics, medicine, and also as feed preservatives.

Before further describing the specific embodiments of the present invention, it should be understood that the protection scope of the present invention is not limited to the following specific specific embodiments; it should also be understood that the terms used in the examples of the present invention are for describing specific specific embodiments, It is not intended to limit the protection scope of the present invention. In the following examples, the test methods without specific conditions are usually in accordance with conventional conditions or in accordance with the conditions suggested by various manufacturers.

When numerical ranges are given in the examples, it is to be understood that, unless otherwise indicated herein, both endpoints of each numerical range and any number between the two endpoints may be selected. Unless otherwise defined, all technical and scientific terms used in the present invention have the same meaning as commonly understood by one of ordinary skill in the art. In addition to the specific methods, equipment and materials used in the embodiments, according to the mastery of the prior art by those skilled in the art and the description of the present invention, the methods, equipment and materials described in the embodiments of the present invention can also be used Any methods, devices and materials similar or equivalent to those of the prior art can be used to implement the present invention.

Unless otherwise specified, the experimental methods, detection methods and preparation methods disclosed in the present invention all adopt conventional techniques in the technical field.

Example 1

A beauty serum for removing scars and acne marks, the weight percentages of each component raw material are: Centella asiatica extract 7.0%, Honeysuckle flower extract 3.0%, Ling Xiaohua extract 5.0%, Alanylglutamine 8.0%, Propylene diglyceryl acrylate/acrylic acid copolymer 20%, PVM/MA copolymer 2.5%, glycerin 0.6%, methylparaben 0.10%, propylparaben 0.02%, deionized water 53.78%.

Example 2

A beauty serum for removing scars and acne marks, the weight percentages between the raw materials of the components are: Centella asiatica extract 10%, Honeysuckle flower extract 3.5%, Ling Xiaohua extract 3.5%, Alanylglutamine 10%, Propylene diglyceryl acrylate/acrylic acid copolymer 25%, PVM/MA copolymer 2.0%, glycerin 0.5%, methylparaben 0.05%, propylparaben 0.03%, deionized water 45.42%.

Example 3

A beauty serum for removing scars and acne marks, the weight percentages between the raw materials of the components are: Centella asiatica extract 15%, Honeysuckle flower extract 6.0%, Ling Xiaohua extract 6.5%, Alanylglutamine 5%, Propylene diglyceryl acrylate/acrylic acid copolymer 15%, PVM/MA copolymer 3.0%, glycerin 0.8%, methylparaben 0.15%, propylparaben 0.05%, deionized water 48.5%.

Clinical application

1. Research subjects: Outpatients from the Department of Traditional Chinese Medicine and Cosmetology in the South Hospital of the Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, who met the diagnostic criteria and inclusion criteria. 60 patients with acne vulgaris scars were selected. The smallest scar area was 2 cm and the largest was 42 cm, among which 14 cases were ice pick scars, 27 cases were rolling scars, and 49 cases were box-type scars. There were 30 cases in the treatment group, including 2 males and 28 females, the youngest was 21 years old and the oldest was 35 years old. There were 30 cases in the treatment group, including 1 male and 29 females. The youngest was 19 years old and the oldest was 34 years old. There was no significant difference in gender and age between the two groups (P>0.05). Exclusion criteria: patients with a recent history of taking photosensitizing drugs, a history of sun exposure, mental disorders, pregnant women, and scar constitution.

2. Preparation of beauty serum

2.1 Main component manufacturers and product numbers

Centella asiatica extract: Shanghai Yttrium Chemical Technology Co., Ltd., product number YH-51512. The solid content was more than 3.5%, and the main active ingredients were asiaticoside, madecassoside, asiatic acid and madecassoic acid. Pharmacological action It has inhibitory effect on Staphylococcus aureus, Streptococcus hemolyticus, various Shigella spp. and Typhoid bacillus, and also affects the viability of scar fibroblasts. Clinically used to promote wound healing and inhibit scar proliferation. Extraction process: 1. Centella asiatica washing, crushing 2.1,3 Propylene glycol heating extraction 3. Filtration (300 mesh filter) 4. Cloth filtration 5. Paper filtration 6. Heating concentration 7. Quality inspection 8. Freezing 9. Thawing adjustment (adjust PH, etc.) 10. Nanofiltration 11. Sterilization 12. Anticorrosion 13. Quality inspection 14. Packaging.

Lingxiaohua extract: Shanghai Yttrium Chemical Technology Co., Ltd., product number YH-52868. The solid content is 3.5%-10%, and the main active ingredients are triterpenes, flavonoids, anthocyanins, volatile oils, etc. Pharmacological effects include improving blood circulation, inhibiting thrombosis, analgesia, anti-inflammatory and antioxidant effects. Clinically used for acne, hormone-dependent dermatitis and other skin diseases. Extraction process: 1. Lingxiaohua cleaning, crushing 2.1,3 Propylene glycol heating extraction 3. Filtration (300 mesh filter) 4. Cloth filtration 5. Paper filtration 6. Heating concentration 7. Quality inspection 8. Freezing 9. Thawing adjustment (adjustment PH, etc.) 10. Nanofiltration 11. Sterilization 12. Anticorrosion 13. Quality inspection 14. Packaging.

Honeysuckle extract: Shanghai Yttrium Chemical Technology Co., Ltd., product number YH-51120. The solid content is 3.5%-10%, and the main medicinal components are volatile oils, organic acids, flavonoids, iridoid glycosides, triterpenoid saponins and other components. Pharmacological action Clears heat and detoxifies, cools and dissipates wind-heat. Clinically used: carbuncle treatment sore, throat paralysis, erysipelas. Extraction process: 1. Honeysuckle cleaning, crushing 2.1,3 Propylene glycol heating extraction 3. Filtration (300 mesh filter) 4. Cloth filtration 5. Paper filtration 6. Heating concentration 7. Quality inspection 8. Freezing 9. Thawing adjustment (adjustment PH, etc.) 10. Nanofiltration 11. Sterilization 12. Anticorrosion 13. Quality inspection 14. Packaging.

Power peptide essence powder: Shanghai Yttrium Chemical Technology Co., Ltd. Chinese name: Alanylglutamine, INCI name ALANYL GLUTAMINE, CAS No.39537-23-0. This product is white to light yellow powder, soluble in water, and stable at room temperature. Among them, the content of oligopeptide-1 is 35 wt%, and the content of oligopeptide-3 is 20 wt%, which has the functions of anti-oxidation, delaying skin aging, promoting tissue repair and moisturizing and locking water.

2.2 Preparation method

Follow the steps below to prepare a beauty serum:

Step 1. Mix the above-mentioned Centella asiatica extract, honeysuckle extract, Lingxiaohua extract and force peptide essence powder, and stir at a speed of 100rpm for 1h to obtain a first mixture;

Step 2, mixing propylene diglycerol acrylate/acrylic acid copolymer, PVM/MA copolymer, glycerin, methylparaben, propylparaben, adding deionized water, and stirring at 130rpm for 1h to obtain a second mixture;

Step 3: Mix the first mixture obtained in step 1 and the second mixture obtained in step 2, stir at 180 rpm, and mix evenly to obtain a beauty solution for removing scars and acne marks.

The weight percentage of each component in the cosmetic solution prepared by the above method is: Centella asiatica extract 10%, honeysuckle flower extract 3.5%, Ling Xiaohua extract 3.5%, alanyl glutamine 10%, propylene diglyceryl acrylate /Acrylic copolymer 25%, PVM/MA copolymer 2.0%, glycerin 0.5%, methylparaben 0.05%, propylparaben 0.03%, deionized water 45.42%.

3. Preoperative preparation

Before treatment, medical staff should fully communicate with patients, introduce treatment methods, intraoperative precautions and prevention methods for emergencies to patients, reduce the psychological pressure of patients, and obtain the cooperation and understanding of patients. At the same time, the patient's face was cleaned and photographed under the same light source before the operation.

4. Treatment methods

The treatment group was disinfected with facial disinfectant. Select 0.5mm-1.0mm sterile roller needle for microneedling, hold the above prepared beauty solution in the left hand, stagger and roll 3-5 times in all directions of the local skin, and apply the beauty solution while rolling, until the local skin is swollen. treatment endpoint. Within 24 hours after treatment, the treated area should not be exposed to raw water, and pay attention to moisturizing and sun protection. Treatment 1-6 times, 2 times a month.

In the control group, the face disinfectant was disinfected. For microneedling treatment, 0.5mm-1.0mm sterile needles are selected, and the needles are staggered and rolled 3-5 times in all directions of the local skin until the local skin becomes swollen as the end point of the treatment. Immediately after the treatment, apply asiaticoside ointment to the scar. Do not touch the treated area with raw water within 24 hours after the treatment, and pay attention to moisturizing and sun protection. Treatment 1-6 times, 2 times a month.

5. Treatment results

5.1 Efficacy criteria

(1) Recovery: The degree of repair of the patient's scar depression reaches 90%;

(2) Significantly effective: The degree of repair of the patient's scar depression is up to 60%, the appearance is smooth, and the uneven color is significantly reduced;

(3) Effective: the degree of repair of the patient's scar depression is 30% to 59%, the appearance is improved to a certain extent, and the uneven color is significantly reduced;

(4) Invalid: the degree of scar depression is less than 30% repaired, and the appearance does not change or even aggravates.

Total effective rate = (number of cured cases + number of markedly effective cases + number of effective cases)/total number of cases × 100%.

5.2 Subjective satisfaction survey of patients. According to the subjective evaluation of the patients' satisfaction with the treatment effect and treatment experience, the indicators were divided into very satisfied, satisfied and dissatisfied, and the satisfaction rate = (very satisfied + satisfied)/number of cases × 100%.

5.3 The occurrence of adverse reactions in the two groups was compared. Common adverse reactions are facial infection, skin allergy or sensitivity, pigmentation, other (pigmentation, new acne, erythema and edema).

5.4 Statistical analysis

SPSS 22.0 was used to analyze the research data, and the count data were expressed as percentage (%), and χ ² test was performed. P<0.05, indicating that the difference was statistically significant.

5.5 Results

5.5.1 The therapeutic effect is shown in Table 1 below:

Table 1 Comparison of curative effect of two groups of patients

Note: χ ² =7.34 ¹⁾ P<0.05, the effective rate of the treatment group was higher than that of the control group.

It can be seen from the statistical results in Table 1 that the curative effect of using the cosmetic solution provided by the present invention in combination with roller needles in treating scar depression and acne marks is better than that of asiaticoside ointment, indicating that the cosmetic solution provided by the present invention has a good effect of removing scars and acne marks.

5.5.2 Observation of adverse reactions

Table 2 Comparison of adverse reactions between the two groups of patients

Note: χ ² =5.24P<0.05, the incidence of adverse reactions in the treatment group was lower than that in the control group.

From the statistical results in Table 2, it can be seen that the incidence of adverse reactions of using the cosmetic solution provided by the present invention in combination with roller needles to treat scar depression and acne marks is lower than that of asiaticoside ointment, indicating that the cosmetic solution provided by the present invention can reduce the side effects of microneedle treatment. .

5.5.3 Satisfaction survey

The satisfaction rate of the treatment group was 95.53%, which was significantly higher than that of the control group, 76.47%, and the difference was statistically significant (P<0.05). The satisfaction of the patients in the treatment group to the treatment experience was 93.33%, which was significantly higher than that in the control group (66.67%), and the difference was statistically significant (P<0.05). Among them, the VRS method was used in the treatment experience satisfaction survey to allow the patients in the treatment group and the control group to evaluate the pain and burning sensation during the treatment process respectively. The evaluation results of the patients in the treatment group were 19 cases of mild pain and 11 cases of moderate pain. There were 5 patients with mild pain, 18 patients with moderate pain and 7 patients with severe pain.

Typical cases

Case 1: Chen Moumou, female, 30 years old, employee of Shanghai Hospital. Due to repeated acne for three months and left pigment scars for more than one month, he went to our hospital for treatment in November 2020. Figure 1 is a photo archived before treatment. Once a week, a total of 4 treatments. Figure 2 is the archived photos after the treatment. It can be clearly seen that the color of several acne marks on the cheeks has obviously faded, and some of them have disappeared, and the facial skin is fairer and firmer than before.

Case 2: Sun Moumou, female, 27 years old, working white-collar worker in Shanghai. He has a history of acne for many years, and after self-administration of topical hormone drugs, secondary to rough skin and pigmentation. I came to our hospital for treatment in November 2020. Figure 3 shows the photos before the treatment; I used the present invention to remove scars and acne marks in combination with needle roller treatment, once every two weeks, for a total of 4 treatments. Figure 4 is the archived photos after treatment. It can be clearly seen that the acne pits on both cheeks have become lighter, the pigmentation of acne marks has become lighter, and the skin pores have shrunk, which is more delicate and fairer than before the treatment.

Case 3: Jin Moumou, male, 19 years old, a student in Shanghai. The history of acne is 2 years, and there are obvious concave acne pits locally, and cystic acne on the lower jaw. In December 2020, he came to our hospital for treatment. Fig. 5 is a photo archived before treatment; Needle rolling treatment, once a week, after four times of treatment, Figure 6 is the archived photos after treatment, it can be clearly seen that the cystic acne has shrunk and disappeared, and the acne marks have disappeared. I sent a few pieces and left acne marks. At the patient’s initiative, I received 2 treatments. Figure 7 and Figure 8 are the photos after the two treatments. It can be clearly seen that the acne marks have faded, and the skin is smoother and tighter than before. To.

The above are only preferred embodiments of the present invention, and are not intended to limit the present invention in any form or substance. It should be pointed out that for those skilled in the art, without departing from the method of the present invention, the Several improvements and supplements can be made, and these improvements and supplements should also be regarded as the protection scope of the present invention. All those skilled in the art, without departing from the spirit and scope of the present invention, can utilize the above-disclosed technical content to make some changes, modifications and equivalent changes of evolution, all belong to the present invention. Equivalent embodiments; at the same time, any modification, modification and evolution of any equivalent changes made to the above embodiments according to the essential technology of the present invention still fall within the scope of the technical solutions of the present invention.

Claims (10)

1. The scar and acne mark removing beauty lotion is characterized by comprising the following raw materials: centella asiatica extract, honeysuckle flower extract, trumpet creeper flower extract, alanyl glutamine, propylene diglycerol acrylate/acrylic acid copolymer, PVM/MA copolymer, glycerin, methyl hydroxybenzoate, propyl hydroxybenzoate and deionized water.

2. The cosmetic liquid as claimed in claim 1, wherein the weight percentage of the raw materials of each component is as follows: 3.5-20% of centella extract, 1.5-10% of honeysuckle extract, 1.5-10% of trumpet creeper extract, 5.0-20.0% of alanyl glutamine, 15-55% of propylene diglycerol acrylate/acrylic acid copolymer, 1.0-4.0% of PVM/MA copolymer, 0.1-1.0% of glycerol, 0.01-0.15% of methyl hydroxybenzoate, 0.01-0.05% of propyl hydroxybenzoate and 35-55% of deionized water.

3. The cosmetic liquid according to claim 1, wherein the weight percentages of the raw materials of the components are as follows: centella asiatica extract 10%, honeysuckle extract 3.5%, Chinese trumpet creeper extract 3.5%, alanyl glutamine 10%, propylene diglycerol acrylate/acrylic acid copolymer 25%, PVM/MA copolymer 2.0%, glycerin 0.5%, methyl hydroxybenzoate 0.05%, propyl hydroxybenzoate 0.03%, and deionized water 45.42%.

4. A method for preparing a cosmetic liquid according to any one of claims 1 to 3, comprising the steps of:

s1, stirring the centella extract, the honeysuckle extract, the campsis grandiflora extract and the alanyl glutamine to obtain a first mixture;

s2, stirring propylene diglycerol acrylate/acrylic acid copolymer, PVM/MA copolymer, glycerol, methyl hydroxybenzoate, propyl hydroxybenzoate and deionized water to obtain a second mixture;

s3, mixing the first mixture obtained in the step S1 and the second mixture obtained in the step S2, stirring, and uniformly mixing to obtain the scar and acne mark removing cosmetic liquid.

5. The method of claim 4, further comprising one or more of the following features:

(1) in the step S1, the stirring speed is 60-150 rpm, and the stirring time is 0.5-1 h;

(2) in the step S2, the stirring speed is 100-200 rpm, and the stirring time is 0.5-1 h;

(3) in the step S3, the stirring speed is 100-200 rpm, and the stirring time is 0.5-1 h.

6. Use of a cosmetic liquid according to any one of claims 1 to 3 for removing scars and acne marks.

7. Use of a cosmetic liquid according to any one of claims 1 to 3 in the manufacture of a medical or cosmetic product for scar repair or acne mark removal.

8. Use of a cosmetic liquid according to any one of claims 1 to 3 for the preparation of a cosmetic product having any one of the following effects: 1) repairing depressed scars of the skin; 2) reduction of acne pigmentation; 3) cystic acne with detumescence and stagnation eliminating effects; 4) inhibiting acne scar formation and hyperplasia.

9. Use of a cosmetic liquid according to any one of claims 1 to 3 for the preparation of a microneedle base fluid.

10. A scar and acne mark removing cosmetic product comprising the cosmetic liquid according to any one of claims 1 to 3.

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