CN114746070A - Sunscreen compositions with multiple photoprotective UV filters - Google Patents

Abstract

Provided is a UV filter composition comprising: three UV-B filters; a UV-A filter; and UV-A + UV-B broadband filters.

Description

Sunscreen compositions with multiple photoprotective UV filters

Related applications

This application claims US Provisional Patent Application Serial No. 62/937,989, filed November 20, 2019, entitled "SUNSCREEN COMPOSITIONS WITH MULTIPLE PHOTOPROTECTING UV FILTERS" To the benefit of priority, the disclosure of said provisional patent application is incorporated herein by reference in its entirety. This application also claims the benefit of priority to US Provisional Patent Application Serial No. 62/948,990, filed December 17, 2019, entitled "Sunscreen Compositions with Multiple Photoprotective UV Filters," which The disclosure of the patent application is incorporated herein by reference in its entirety.

Disclosed herein are novel compositions for use as sunscreens including various photoprotective UV filters. Combinations of UV filters provide effective protection from a wide range of UV wavelengths when applied to exposed skin.

technical field

Background technique

Exposure to sunlight can cause health hazards, the significance of which has increased in recent decades. Acute exposure to sunlight may result in sunburn, which is characterized by skin irritation and redness. What's more, prolonged exposure to the sun increases the risk of skin cancer. Of the various subtypes of skin cancer, melanoma has the greatest risk because it is aggressive and difficult to treat if not caught before it spreads. The American Cancer Society estimates that nearly 100,000 melanoma cases will be diagnosed in 2019, along with about 7,000 deaths. Finally, exposure to sunlight can cause premature skin aging, hair damage, and eye damage (including cataracts).

The ultraviolet region of solar radiation falling between 200nm and 400nm can be classified into three regions: 320nm to 400nm (UV-A), 290nm to 320nm (UV-B) and 200nm to 290nm (UV-C), the latter (UV-C) does not normally penetrate the Earth's atmosphere. Historically, more attention has been paid to the health risks of UV-B exposure; however, more recently, more is learned about the potential harm that may be caused by UV-A, as well as melanoma and other skin cancers. Therefore, protection from excessive UV-A and UV-B radiation is an important part of personal care.

Although sunscreens have been used on the market for a long time, newly discovered health and (especially) environmental concerns are prompting the development of new compounds and compositions for improved preventive properties and increased consumer acceptance. There is a significantly unmet need for a method for new sunscreens. The present disclosure meets these and other needs, as evidenced by reference to the following disclosure.

The present invention provides a sunscreen composition.

Provided is a UV filter composition comprising: three UV-B filters; UV-A filters; and UV-A+UV-B broadband filters.

SUMMARY OF THE INVENTION

Also provided is a sunscreen composition comprising the UV filter composition described herein.

Also provided is a method for protecting skin from sun damage, the method comprising applying to the skin a sunscreen composition described herein.

These and other aspects of the present invention will become apparent with reference to the following detailed description. To this end, various references are set forth herein that describe certain background information, procedures, compounds and/or compositions in greater detail, and each of which is hereby incorporated by reference in its entirety.

Description of drawings

The accompanying drawings generally illustrate, by way of example and not limitation, the various embodiments discussed in this document.

1 is a graph according to Example 5 showing that the in vivo SPF of Formulas 1 and 2 are substantially the same as the SPF of the Comparative Formula.

2 is a graph according to Example 5 showing that the PPD of Equation 1 is substantially the same as the Comparative Equation.

3 is a graph according to Example 5 showing that the SPF/PPD quotient of Equation 1 is substantially the same as the Comparative Equation.

4 is a graph according to Example 5 showing the improvement of the SPF of Equation 3 over the Comparative Equation.

5 is a graph according to Example 5 showing that the SPF/PPD quotient of Equation 3 is substantially the same as the Comparative Equation.

6 is a graph according to Example 5 showing that the SPF/PPD quotient of Equation 3 is substantially the same as the Comparative Equation.

Detailed ways

In the following description, certain specific details are set forth in order to provide a thorough understanding of various embodiments. However, one of ordinary skill in the art will understand that the present invention may be practiced without these details. In other instances, well-known structures have not been shown or described in detail to avoid unnecessarily obscuring the description of the embodiments. Throughout the specification and the appended claims, the word "comprise" and variations thereof, such as "comprises" and "comprising," are to be used open-ended and inclusive unless the context requires otherwise, unless the context requires otherwise. , that is, to be interpreted as "including but not limited to". Furthermore, headings provided herein are for convenience only and do not delineate the scope or meaning of the claimed invention.

Throughout this specification, reference to "one embodiment" or "anembodiment" or "some embodiments" or "a certain embodiment" is meant to incorporate A particular feature, structure, or characteristic described in this embodiment is included in at least one embodiment. Thus, appearances of the phrases "in one embodiment" or "in an embodiment" or "in some embodiments" or "in an embodiment" in various places throughout this specification are not necessarily all referring to the same embodiment . Furthermore, the particular features, structures or characteristics may be combined in any suitable manner in one or more embodiments.

Also, as used in this specification and the appended claims, the singular forms "a", "an", and "the" include plural referents unless the content clearly dictates otherwise. thing.

Where applicable, chemicals are assigned according to their INCI names. Additional information, including definitions, suppliers, and trade names, can be found in the International Cosmetic Ingredient Dictionary and Handbook, 16th Edition, published by the Personal Care Products Council, Washington D.C. found in the appropriate INCI monograph. Also available through the Personal Care Products Council On-LineINFOBASE (http://online.personalcarecouncil.org/jsp/Home.jsp).

When a range of values is disclosed and the notation "from n ₁ to n ₂ " or "between n ₁ and n ₂ " is used, where n ₁ and n ₂ are numbers, then unless otherwise stated, the notation is intended to be In the range that contains the number itself and the number. This range may be an integer or may continue between and inclusive of the endpoints. For example, the range "2 to 6 carbons" is intended to include two, three, four, five, and six carbons because carbons are present in integer units. For example, compare 1 μM to 3 μM (micromoles) intended to encompass 1 μM, 3 μM, and each number in between to any of the significant digits (eg, 1.255 μM, 2.1 μM, 2.9999 μM, etc.).

As used herein, the term "about" is intended to quantify the numerical value it modifies, thereby indicating that such value is variable within a margin of error. When a specific margin of error is not recited, such as standard deviation from the mean given in a graph or table of data, the term "about" should be understood to mean that both the range of the recited value and by rounding to the number stated will be encompassed range, taking significant figures into account.

Unless otherwise specified, percentages or concentrations refer to percentages or concentrations by weight (ie, % (W/W)). Unless otherwise stated, all ranges are inclusive, eg, "from 4 to 9" includes the endpoints 4 and 9.

As used herein, the term "cosmetically effective amount" refers to an amount of a physiologically active compound or composition sufficient to treat one or more conditions but low enough to avoid serious side effects. The cosmetically effective amount of the compound or composition will vary with the condition being treated, the age and physical condition of the end user, the severity of the condition being treated/prevented, the duration of the treatment, the nature of the other treatments, the particular compound employed or The product/composition, the cosmetically acceptable carrier used, and the like vary.

As used herein, the term "cosmetically acceptable" means that its ingredients are suitable for use in contact with tissue (eg, skin) without undue toxicity, irritation, incompatibility, instability, allergic reactions, or other adverse effects Compositions.

The term "sun protection factor", abbreviated "SPF", or "UV protection factor" was determined using a combination of experimental and theoretical absorption data disclosed in US 6,820,014, incorporated herein by reference. enter. Other methods for determining SPF are known in the art.

The term "persistent pigmentation", abbreviated as "PPD," is a measure of UVA protection, similar to the SPF method of sunburn protection. Instead of measuring erythema, the PPD method uses UVA radiation to induce persistent darkening or tanning of the skin. In theory, a sunscreen with a PPD rating of 10 should allow 10 times more UVA exposure than no protection. Methods for determining PPD are known in the art.

As used herein, the term "UV-A" refers to electromagnetic radiation having a wavelength between 320 nm and 400 nm.

As used herein, the term "UV-B" refers to electromagnetic radiation having a wavelength between 290 nm and 320 nm.

As used herein, the term "broad spectrum" UV refers to electromagnetic radiation having a wavelength of 290 nm to 400 nm. The measurement of "broad spectrum" was carried out according to 21 C.F.R. 201.327(j)(2019).

As used herein, the term "critical wavelength" is the wavelength at which the integral of the spectral absorbance curve is 90% of the integral within the UV spectrum from 290 nm to 400 nm.

As used herein, the term "photostable" refers to the ability of a molecule to remain intact under irradiation. Photostability can be quantified later by comparing the degree of protection and exposure. See e.g. Pissavini et al. (2012) "New Method to Reproduce In Vitro Cosmetic Product Photostability Findings", Cosmetics & Toiletries 127(3): 208-218, which are incorporated by reference for all purposes. Photostability can also be determined using other methods known in the art.

As used herein, the term "topical application" refers to direct application by spraying, wiping, or coating on the outer skin or scalp. Topical application can be done by hand, or using an applicator such as a wipe, roller, or spray.

As used herein, the term "cosmetic agent" refers to a beautifying substance or formulation that maintains, restores, imparts, simulates, or enhances the beautiful appearance of the body or the appearance of enhancing beauty or youth, particularly as it relates to the appearance of tissue or skin.

As used herein, the term "sunscreen composition" refers to formulations that absorb and/or reflect some of the sun's ultraviolet (UV) radiation, including but not limited to: sprays, oils, lotions, creams, gels Gels, butters, pastes, ointments, sticks, powders, wipes, towels, body washes, shampoos, or other topical products. The sunscreen composition will thus provide protection against the negative effects of sun exposure, eg, sunburn, premature aging, and the like.

Provided is a UV filter composition comprising: three UV-B filters; UV-A filters; and UV-A+UV-B broadband filters. Also provided is a UV filter composition consisting of: three UV-B filters; a UV-A filter; and a UV-A+UV-B broadband filter.

In certain embodiments, the UV-A filter is selected from:

butylmethoxydibenzoylmethane or 1-(4-tert-butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione;

· terephthalimethylene dicamphorsulfonic acid or 3,3'-(1,4-phenylenedimethylene)bis(7,7-dimethyl-2-oxobicyclo-[2.2.1] ]hept-1-ylmethanesulfonic acid) and its salts;

Menthyl anthranilate;

· Bisdisulizole Disodium or disodium phenyldibenzimidazole tetrasulfonate;

Diethylaminohydroxybenzoylhexylbenzoate; and

• Dimethoxyphenyl-[1-(3,4)]-4,4-dimethyl 1,3-pentanedione.

In certain embodiments, the UV-A filter is selected from the group consisting of butylmethoxydibenzoylmethane, diethylaminohydroxybenzoylhexylbenzoate, disodium phenyldibenzimidazole tetrasulfonate, and terephthalimethylene dicamphorsulfonic acid.

In certain embodiments, the UV-A filter is selected from the group consisting of butylmethoxydibenzoylmethane and menthyl anthranilate.

In certain embodiments, the UV-A filter is butylmethoxydibenzoylmethane.

In certain embodiments, the three UV-B filters are independently selected from:

3-benzylidene camphor;

benzylidene camphorsulfonic acid;

enzacamene or 4-methylbenzylidene camphor or 4-MBC;

2-ethoxyethyl-p-methoxyoctanoate;

DEA Methoxycinnamate;

· Iscotrizinol or diethylhexylbutyramidotriazinone or benzoic acid, 4,4-{[6-[[[(1,1-dimethylethyl)amino]carbonyl]benzene yl]amino]-1,3-5-triazine-2,4-diyl]diimino}bis-,bis(2-ethylhexyl)ester;

·Diploid trioleate;

Diisopropylmethyl cinnamon;

·Ethyldihydroxypropyl PABA;

Dimethoxybenzylidene dioximidazole propionate ethylhexyl;

octyldimethyl-PABA or 2-ethylhexyl 4-(dimethylamino)benzoate;

octyl methoxycinnamate or 2-ethylhexyl 4-methoxycinnamate;

octyl salicylate or 2-ethylhexyl salicylate;

octyltriazinone or ethylhexyltriazinone or 2,4,6-triphenylamino-(p-carbon-2'-ethylhexyl-1'-oxy)-1,3,5-triazine ;

Ferulic acid;

glyceryl ethylhexanoate dimethoxycinnamate;

Glyceryl PABA;

· Benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester;

isoamyl p-methoxycinnamate or isoamyl-4-methoxycinnamate;

Isopentyl trimethoxycinnamate trisiloxane;

isopropyl benzyl salicylate;

Isopropyl Methoxycinnamate;

· Lawsone + dihydroxyacetone;

4-methylbenzylidene camphor;

2-ethylhexyl 2-cyano-3,3-diphenylacrylate;

· aminobenzoic acid (PABA);

·PEG-25PABA;

· Amyl dimethyl PABA;

phenylbenzimidazole sulfonic acid or 2-phenylbenzimidazole-5-sulfonic acid and its potassium, sodium and triethanolamine salts;

Polyacrylamidomethylbenzylidene camphor;

Polysiloxane-15 or Dimethicone Diethylbenzylidene Malonate;

salicylic acid; and

Salicylic acid TEA (triethanolamine salicylate).

In certain embodiments, the three UV-B filters are independently selected from ethylhexyldimethyl PABA, ethylhexyl methoxycinnamate, ethylhexyl salicylate, homosalate ( homosalate), octocrylene, PABA and phenylbenzimidazole sulfonic acid. In certain embodiments, any of the compositions described herein may be free of octocrylene.

In certain embodiments, the three UV-B filters are independently selected from the group consisting of 3-benzylidene camphor, benzylidene camphor sulfonic acid, camphor benzalkonium methyl sulfate, diethylhexylbutanamidotri Azinone, Ethylhexyldimethyl PABA, Ethylhexyl Methoxycinnamate, Ethylhexyl Salicylate, Ethylhexyl Triazinone, Homosalate, Isoamyl p-Methoxycinnamate , 4-methylbenzylidene camphor, octocrylene, PABA, PEG-25PABA, phenylbenzimidazole sulfonic acid, polyacrylamidomethylbenzylidene camphor, and polysiloxane-15. In certain embodiments, the three UV-B filters are independently selected from cinoxate, ethylhexyldimethyl PABA, ethylhexyl methoxycinnamate, ethyl salicylate Hexyl ester, homosalate, octocrylene, PABA, phenylbenzimidazole sulfonic acid, and salicylic acid TEA. In certain embodiments, the three UV-B filters are independently selected from isoamyl p-methoxycinnamate, ethylhexyl triazinone, diethylhexyl butyramidotriazinone, and salicylic acid Ethylhexyl ester. In certain embodiments, the three UV-B filters are independently selected from isoamyl p-methoxycinnamate, ethylhexyl triazinone, and octyl salicylate.

In certain embodiments, the broadband UV-A and UV-B filters are selected from:

·Benzophenone;

· Benzophenone-1;

· Benzophenone-2;

· Benzophenone-3 or 2-hydroxy-4-methoxybenzophenone;

Benzophenone-4 or 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid (benzophenone-5) and its sodium salt;

· Benzophenone-5;

· Benzophenone-6;

· Dioxybenzone (Dioxybenzone, benzophenone-8);

· Benzophenone-9;

β-2-glucopyranosyloxypropylhydroxybenzophenone;

Bemotrizinol or bis-ethylhexyloxyphenol methoxyphenyltriazine or 2,2'-(6-(4-methoxyphenyl)-1,3,5- Triazine-2,4-diyl)bis(5-((2-ethylhexyl)oxy)phenol);

Crestrozole (Drometrizole);

Trazole trisiloxane cresol or phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-6-(2-methyl-3-(1,3,3,3) - tetramethyl-1-(trimethylsilyl)oxy)-disiloxyl)propyl;

Bisoctrizol or methylenebis-benzotriazolyltetramethylbutylphenol;

Titanium dioxide; and

·Zinc oxide.

In certain embodiments, the broadband UV-A and UV-B filters are selected from benzophenone-3 and titanium dioxide. In certain embodiments, the broadband UV-A and UV-B filters are selected from the group consisting of benzophenone-3, benzophenone-4, benzophenone-5, bis-ethylhexyloxyphenol methyl Oxyphenyl triazine, cresol trazole trisiloxane, methylene bis-benzotriazolyl tetramethylbutylphenol and titanium dioxide. In certain embodiments, the broadband UV-A and UV-B filters are selected from the group consisting of benzophenone-3, benzophenone-4, benzophenone-8, titanium dioxide, and zinc oxide. In certain embodiments, the UV-A+UV-B broadband filter is bisethylhexyloxyphenolmethoxyphenyltriazine.

Also provided is a UV filter composition comprising isoamyl p-methoxycinnamate, ethylhexyl triazinone, octyl salicylate, butylmethoxydibenzoylmethane and bis-ethylhexyl Oxyphenol methoxyphenyl triazine.

Also provided is a UV filter composition consisting of isoamyl p-methoxycinnamate, ethylhexyl triazinone, octyl salicylate, butylmethoxydibenzoylmethane and bis- Ethylhexyloxyphenol methoxyphenyl triazine.

Also provided is a UV filter composition comprising diethylhexylbutyramidotriazinone, ethylhexyltriazinone, octyl salicylate, butylmethoxydibenzoylmethane and bis-ethyl Hexyloxyphenol methoxyphenyl triazine.

Also provided is a UV filter composition consisting of: diethylhexyl butyramidotriazinone, ethylhexyltriazinone, octyl salicylate, butylmethoxydibenzoylmethane, and bismuth -Ethylhexyloxyphenolmethoxyphenyltriazine.

Also provided is a UV filter composition comprising diethylhexylbutyramidotriazinone, isoamyl p-methoxycinnamate, octyl salicylate, butylmethoxydibenzoylmethane and bis -Ethylhexyloxyphenolmethoxyphenyltriazine.

Also provided is a UV filter composition, which is composed of the following: diethylhexylbutyramidotriazinone, isoamyl p-methoxycinnamate, octyl salicylate, butylmethoxydibenzoyl Methane and bis-ethylhexyloxyphenol methoxyphenyl triazine.

Also provided is a sunscreen composition comprising a UV filter composition comprising isoamyl p-methoxycinnamate, ethylhexyl triazinone, octyl salicylate, Butylmethoxydibenzoylmethane and bis-ethylhexyloxyphenolmethoxyphenyltriazine.

Also provided is a sunscreen composition comprising a UV filter composition comprising diethylhexylbutyramidotriazinone, ethylhexyltriazinone, octyl salicylate , butylmethoxydibenzoylmethane and bis-ethylhexyloxyphenolmethoxyphenyltriazine.

Also provided is a sunscreen composition comprising a UV filter composition comprising diethylhexylbutanamidotriazinone, isoamyl p-methoxycinnamate, water Octyl cylate, butylmethoxydibenzoylmethane, and bis-ethylhexyloxyphenolmethoxyphenyltriazine.

In certain embodiments, the sunscreen composition does not include nanoparticles.

In certain embodiments, the sunscreen composition does not include benzophenone-3.

In certain embodiments, the sunscreen composition does not include octyl methoxycinnamate.

In certain embodiments, the composition does not include a cinnamate other than isoamyl p-methoxycinnamate.

In certain embodiments, the sunscreen composition does not include 2-ethylhexyl 2-cyano-3,3-diphenylacrylate.

In certain embodiments, the sunscreen composition excludes 2-(benzotriazol-2-yl)-4,6-di-tert-butylphenol, 2,4-di-tert-butyl-6-( 5-Chlorobenzotriazol-2-yl)phenol, 2-(benzotriazol-2-yl)-4,6-bis-(1,1-dimethylpropyl)-phenol or 2-( Benzotriazol-2-yl)-6-butan 2-yl-4-tert-butylphenol.

In certain embodiments, each of the UV filters in the sunscreen composition is present at about 0.1 w/w% to about 25 w/w%, about 0.1 w/w% to about 20 w/w% , about 0.1w/w% to about 18w/w%, 0.1w/w% to about 15w/w%, about 0.1w/w% to about 12w/w%, about 0.1w/w% to about 10w/w %, 0.1 w/w% to about 8 w/w%, about 0.1 to about 6 w/w%, wherein the weight percent is based on the total weight of the sunscreen composition.

In certain embodiments, the sunscreen composition includes less than about 35 w/w% UV filter. In certain embodiments, the sunscreen composition includes between about 5 w/w% and about 25 w/w% UV filter. In certain embodiments, the sunscreen composition includes about 20 w/w% UV filter.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter diethylhexylbutyramidotriazinone, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenolmethoxyphenyltriazine.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazine, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenolmethoxyphenyltriazine.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter is about 2:7:1.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 2:5.5:1.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:1.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter is about 2:7:1.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 4:11:2.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:3:1.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter is about 4:13:2.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 4:13:2.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:13:2.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter was about 6:17:6.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 6:17:4.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:6.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter was about 7:13:6.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 6:17:4.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:13:6.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter is about 1:2:1.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 3:8.5:2.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:2:1.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyl triazinone, UV-B filter salicyl Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter is about 7:11:6.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyl triazinone, UV-B filter salicyl Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 7:11:6.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:11:6.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter is about 9:24:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyl triazinone, UV-B filter salicyl Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 9:20:7.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyl triazinone, UV-B filter salicyl Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter was about 9:19:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 9:19:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter is about 9:17:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 9:20:7.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:17:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter is about 9:25:7.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 9:25:7.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:25:7.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter is about 9:23:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 9:23:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:23:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter is about 9:18:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 9:20:7.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter is about 9:18:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 9:20:7.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter is about 9:15:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 9:14:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:15:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter is about 9:16:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 9:14:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:16:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, UV-B filter isoamyl p-methoxycinnamate, and broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine, where UV-A The mass ratio of filter to UV-B filter to broadband filter is about 9:15:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter ethylhexyltriazinone, UV-B filter salicin Octyl acid, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyltriazine, where UV- The mass ratio of A filter to UV-B filter to broadband filter is about 9:14:8.

In certain embodiments, the sunscreen composition includes the following: UV-A filter butylmethoxydibenzoylmethane, UV-B filter isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, the UV-B filter diethylhexylbutyramidotriazinone, and the broadband UV-A and UV-B filters bis-ethylhexyloxyphenol methoxyphenyltriazine, The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:15:8.

In certain embodiments, the ratio of UVA/UVB filters in the sunscreen composition is between about 0.6 and about 0.8. In certain embodiments, the ratio of UVA/UVB filters in the sunscreen composition is about 0.7.

In certain embodiments, the mean critical wavelength of the sunscreen composition is about 370 nm or greater. In certain embodiments, the mean critical wavelength of the sunscreen composition is about 375 nm.

In certain embodiments, the SPF of the sunscreen composition is at least about 15, such as about 15. In certain embodiments, the SPF of the composition is at least about 30. In certain embodiments, the composition has an SPF of at least about 50. In certain embodiments, the SPF of the composition is at least about 60.

In certain embodiments, the sunscreen composition further includes a solubilizer. In certain embodiments, the solubilizer acts to dissolve the UV filter. In certain embodiments, the solubilizer acts to prevent the formation of solid particles. In certain embodiments, sunscreen compositions include lower levels of solubilizers. In certain embodiments, the ratio of UV solubilizer to UV filter is between about 0.5 and about 2.3, such as 0.5, about 0.6, about 0.7, about 0.8, about 0.9, about 1, about 1.1, about 1.2 , about 1.3, about 1.4, about 1.5, about 1.6, about 1.7, about 1.8, about 1.9, or about 2.0.

In certain embodiments, the sunscreen composition includes up to about 36 w/w% solubilizer. In certain embodiments, the sunscreen composition includes about 20 w/w% solubilizer. In certain embodiments, the sunscreen composition includes less than about 20 w/w% solubilizer. In certain embodiments, the sunscreen composition includes between about 15 w/w% and 20 w/w% of a solubilizer.

In certain embodiments, the sunscreen composition includes between about 0.1 w/w% to about 5 w/w% of a solubilizer. In certain embodiments, the sunscreen composition includes between about 0.1 w/w% to about 15 w/w% of a solubilizer. In certain embodiments, the sunscreen composition includes between about 0.1 w/W% to about 25 w/W% of a solubilizer. In certain embodiments, the sunscreen composition includes between about 0.1 w/w% to about 35 w/w% of a solubilizer.

In certain embodiments, the sunscreen composition includes at least one solubilizer selected from the group consisting of: diisopropyl sebacate, dioctyl carbonate , decyl cocoate, diisopropyl adipate, isopropyl lauroyl sarcosine, dibutyl adipate, butyl octyl salicylate, C12-15 alkyl benzoate and succinate diethylhexyl acid. In certain embodiments, the sunscreen composition includes at least one solubilizer selected from the group consisting of: diisopropyl sebacate, diisopropyl adipate, dioctyl carbonate, hexamethylene Dibutyl diacid, butyl octyl salicylate, decyl cocoate, C12-15 alkyl benzoate, diethylhexyl succinate, diethylhexyl carbonate and lauroyl sarcosine isopropyl ester.

In certain embodiments, the sunscreen composition includes two solubilizers selected from the group consisting of: diisopropyl sebacate, diisopropyl adipate, dioctyl carbonate, adipic acid Dibutyl, butyl octyl salicylate, decyl cocoate, C12-15 alkyl benzoate, diethylhexyl succinate, diethylhexyl carbonate and isopropyl lauroyl sarcosine ester. In certain embodiments, the sunscreen composition includes three solubilizers selected from the group consisting of: diisopropyl sebacate, diisopropyl adipate, dioctyl carbonate, adipic acid Dibutyl, butyl octyl salicylate, decyl cocoate, C12-15 alkyl benzoate, diethylhexyl succinate, diethylhexyl carbonate and isopropyl lauroyl sarcosine ester.

In certain embodiments, the sunscreen composition includes 0.1 w/w% to 5 w/w% of ethylhexyl salicylate and optionally at least one additional solubilizer.

In certain embodiments, the sunscreen composition includes 0.1 w/w % to 25 w/w % of at least one solubilizer selected from the group consisting of: dibutyl adipate, C12-15 alkanes benzoate, diethylhexyl succinate, diethylhexyl carbonate and isopropyl lauroyl sarcosine and optionally at least one additional solubilizer.

In certain embodiments, the sunscreen composition includes 0.1 w/w% to 25w/w% of at least one solubilizer selected from the group consisting of: diisopropyl sebacate, adipic acid Diisopropyl, dioctyl carbonate and decyl cocoate and optionally at least one additional solubilizer.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:1, and

wherein the composition comprises a solubilizer diisopropyl sebacate, such as about 5% to about 9% diisopropyl sebacate, eg, about 6% to about 8% diisopropyl sebacate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

Wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:5.5:1,

Wherein the composition includes a solubilizer diisopropyl sebacate, such as about 8% to 10% diisopropyl sebacate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:1, and

wherein the composition comprises a solubilizer diisopropyl sebacate, such as about 5% to about 9% diisopropyl sebacate, eg, about 6% to about 8% diisopropyl sebacate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:2, and

wherein the composition comprises a solubilizer diisopropyl sebacate, such as about 5% to about 9% diisopropyl sebacate, eg, about 6% to about 8% diisopropyl sebacate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:11:2, and

Wherein the composition comprises a solubilizer dibutyl adipate, such as about 8% to about 11% dibutyl adipate, for example about 9% to about 10%.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:3:1, and

wherein the composition comprises a solubilizer diisopropyl sebacate, such as about 5% to about 9% diisopropyl sebacate, eg, about 6% to about 8% diisopropyl sebacate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:13:2, and

wherein the composition comprises a solubilizer diisopropyl sebacate, such as about 5% to about 9% diisopropyl sebacate, eg, about 6% to about 8% diisopropyl sebacate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:13:2, and

wherein the composition comprises a solubilizer diisopropyl sebacate, such as about 5% to about 9% diisopropyl sebacate, eg, about 6% to about 8% diisopropyl sebacate.

In certain embodiments, sunscreen compositions include, wherein:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4, and

wherein the composition further comprises diisopropyl sebacate and dioctyl carbonate, such as about 13% to about 15.5% of a mixture of diisopropyl sebacate and dioctyl carbonate, such as about 13.5% to about 15% A mixture of diisopropyl sebacate and dioctyl carbonate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4, and

wherein the composition further comprises diisopropyl sebacate and dioctyl carbonate, such as about 13% to about 15.5% of a mixture of diisopropyl sebacate and dioctyl carbonate, such as about 13.5% to about 15% A mixture of diisopropyl sebacate and dioctyl carbonate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4, and

wherein the composition further comprises diisopropyl sebacate and dioctyl carbonate, such as about 13% to about 15.5% of a mixture of diisopropyl sebacate and dioctyl carbonate, such as about 13.5% to about 15% A mixture of diisopropyl sebacate and dioctyl carbonate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:17:6, and

wherein the composition further comprises decyl cocoate, isopropyl lauroyl sarcosine and dibutyl adipate, such as about 18% to about 20% of decyl cocoate, isopropyl lauroyl sarcosine and hexamethylene A mixture of dibutyl diacids, for example from about 18.5% to about 19.5% of a mixture of decyl cocoate, isopropyl lauroyl sarcosine and dibutyl adipate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4, and

wherein the composition further comprises decyl cocoate, isopropyl lauroyl sarcosine and dibutyl adipate, such as about 18% to about 20% of decyl cocoate, isopropyl lauroyl sarcosine and hexamethylene A mixture of dibutyl diacids, for example from about 18.5% to about 19.5% of a mixture of decyl cocoate, isopropyl lauroyl sarcosine and dibutyl adipate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:13:6, and

wherein the composition further comprises decyl cocoate, isopropyl lauroyl sarcosine and dibutyl adipate, such as about 16% to about 18% of decyl cocoate, isopropyl lauroyl sarcosine and hexamethylene Mixtures of dibutyl diacids, such as about 16.5% to about 17.5% of decyl cocoate, isopropyl lauroyl sarcosine, and dibutyl adipate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:2:1, and

wherein the composition further comprises decyl cocoate and diisopropyl sebacate, such as about 19% to about 21% of a mixture of decyl cocoate and diisopropyl sebacate, for example, about 19.5% to about 20.5% mixture of decyl cocoate and diisopropyl sebacate.

In certain embodiments, sunscreen compositions include, wherein:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 3:8.5:2, and

wherein the composition further comprises decyl cocoate and diisopropyl sebacate, such as about 19% to about 21% of a mixture of decyl cocoate and diisopropyl sebacate, for example, about 19.5% to about 20.5% mixture of decyl cocoate and diisopropyl sebacate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:2:1, and

wherein the composition further comprises decyl cocoate and diisopropyl sebacate, such as about 19% to about 21% of a mixture of decyl cocoate and diisopropyl sebacate, for example, about 19.5% to about 20.5% mixture of decyl cocoate and diisopropyl sebacate.

In certain embodiments, sunscreen compositions include, wherein:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

w wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:11:6, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 19.5% to about 21.5% diisopropyl sebacate, dioctyl carbonate and decyl cocoate , for example, a mixture of about 20% to about 21% of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, sunscreen compositions include, wherein:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 19.5% to about 21.5% diisopropyl sebacate, dioctyl carbonate and decyl cocoate , for example, a mixture of about 20% to about 21% of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:11:6, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 19.5% to about 21.5% diisopropyl sebacate, dioctyl carbonate and decyl cocoate , for example, a mixture of about 20% to about 21% of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4, and

wherein the composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosine, such as about 16% to about 18% of diisopropyl sebacate, decyl cocoate and Mixtures of isopropyl lauroyl sarcosine, for example, a mixture of about 16.5% to about 17.5% diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosine.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4, and

wherein the composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosine, such as about 16% to about 18% of diisopropyl sebacate, decyl cocoate and Mixtures of isopropyl lauroyl sarcosine, for example, a mixture of about 16.5% to about 17.5% diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosine.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:11:6, and

wherein the composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosine, such as about 16% to about 18% of diisopropyl sebacate, decyl cocoate and Mixtures of isopropyl lauroyl sarcosine, for example, a mixture of about 16.5% to about 17.5% diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosine.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 18% to about 22% diisopropyl sebacate, dioctyl carbonate and decyl cocoate A mixture of, for example, about 19% to about 21% of a mixture of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 25% to about 29% diisopropyl sebacate, dioctyl carbonate and decyl cocoate A mixture of, for example, about 26% to about 28% of a mixture of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 25% to about 29% diisopropyl sebacate, dioctyl carbonate and decyl cocoate A mixture of, for example, about 26% to about 28% of a mixture of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

wherein the composition further comprises diisopropyl sebacate and diisopropyl adipate, such as about 32.5% to about 35.5% of a mixture of diisopropyl sebacate and diisopropyl adipate, for example about 33% To about 35% of a mixture of diisopropyl sebacate and diisopropyl adipate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is 9:20:7, and

wherein the composition further comprises diisopropyl sebacate and diisopropyl adipate, such as about 32.5% to about 35.5% of a mixture of diisopropyl sebacate and diisopropyl adipate, for example about 33% To about 35% of a mixture of diisopropyl sebacate and diisopropyl adipate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

wherein the composition further comprises diisopropyl sebacate and diisopropyl adipate, such as about 32.5% to about 35.5% of a mixture of diisopropyl sebacate and diisopropyl adipate, for example about 33% To about 35% of a mixture of diisopropyl sebacate and diisopropyl adipate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

wherein the composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosine, such as about 22.5% to about 25.5% diisopropyl sebacate, decyl cocoate and Mixtures of isopropyl lauroyl sarcosine, such as about 23% to 25% of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosine.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7,

wherein the composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosine, such as about 22.5% to about 25.5% diisopropyl sebacate, decyl cocoate and Mixtures of isopropyl lauroyl sarcosine, such as about 23% to 25% of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosine.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

wherein the composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosine, such as about 22.5% to about 25.5% diisopropyl sebacate, decyl cocoate and Mixtures of isopropyl lauroyl sarcosine, such as about 23% to 25% of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosine.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

wherein the composition further comprises decyl cocoate, isopropyl lauroyl sarcosine and dibutyl adipate, such as about 28% to about 31% of decyl cocoate, isopropyl lauroyl sarcosine and hexamethylene Mixtures of dibutyl diacids, such as about 29% to about 30% of decyl cocoate, isopropyl lauroyl sarcosine, and dibutyl adipate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7, and

wherein the composition further comprises decyl cocoate, isopropyl lauroyl sarcosine and dibutyl adipate, such as about 28% to about 31% of decyl cocoate, isopropyl lauroyl sarcosine and hexamethylene Mixtures of dibutyl diacids, such as about 29% to about 30% of decyl cocoate, isopropyl lauroyl sarcosine, and dibutyl adipate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8, and

wherein the composition further comprises decyl cocoate, isopropyl lauroyl sarcosine and dibutyl adipate, such as about 28% to about 31% of decyl cocoate, isopropyl lauroyl sarcosine and hexamethylene Mixtures of dibutyl diacids, such as about 29% to about 30% of decyl cocoate, isopropyl lauroyl sarcosine, and dibutyl adipate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8, and

wherein the composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosine, such as about 18% to about 22% of diisopropyl sebacate, decyl cocoate and A mixture of isopropyl lauroyl sarcosine, for example, a mixture of about 20% to about 21% diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosine.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8, and

wherein the composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosine, such as about 18% to about 22% of diisopropyl sebacate, decyl cocoate and A mixture of isopropyl lauroyl sarcosine, for example, a mixture of about 20% to about 21% diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosine.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8, and

wherein the composition further comprises diisopropyl sebacate, diisopropyl adipate and decyl cocoate, such as about 29% to about 33% diisopropyl sebacate, diisopropyl adipate Mixtures with decyl cocoate, for example from about 30% to about 32% of diisopropyl sebacate, diisopropyl adipate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8, and

wherein the composition further comprises diisopropyl sebacate, diisopropyl adipate and decyl cocoate, such as about 29% to about 33% diisopropyl sebacate, diisopropyl adipate Mixtures with decyl cocoate, for example from about 30% to about 32% of diisopropyl sebacate, diisopropyl adipate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:17:8, and

wherein the composition further comprises diisopropyl sebacate, diisopropyl adipate and decyl cocoate, such as about 25% to about 28% diisopropyl sebacate, diisopropyl adipate Mixtures with decyl cocoate, for example, a mixture of about 26% to about 27% diisopropyl sebacate, diisopropyl adipate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7, and

wherein the composition further comprises diisopropyl sebacate, diisopropyl adipate and decyl cocoate, such as about 25% to about 28% diisopropyl sebacate, diisopropyl adipate Mixtures with decyl cocoate, for example, a mixture of about 26% to about 27% diisopropyl sebacate, diisopropyl adipate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:17:8, and

wherein the composition further comprises diisopropyl sebacate, diisopropyl adipate and decyl cocoate, such as about 25% to about 28% diisopropyl sebacate, diisopropyl adipate Mixtures with decyl cocoate, for example, a mixture of about 26% to about 27% diisopropyl sebacate, diisopropyl adipate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:25:7, and

wherein the composition further comprises diisopropyl sebacate and dioctyl carbonate, such as about 17% to about 20% of a mixture of diisopropyl sebacate and dioctyl carbonate, such as about 18% to about 19% A mixture of diisopropyl sebacate and dioctyl carbonate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:25:7, and

wherein the composition further comprises diisopropyl sebacate and dioctyl carbonate, such as about 17% to about 20% of a mixture of diisopropyl sebacate and dioctyl carbonate, such as about 18% to about 19% A mixture of diisopropyl sebacate and dioctyl carbonate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:23:8, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 20% to about 23% diisopropyl sebacate, dioctyl carbonate and decyl cocoate A mixture of, for example, about 21% to about 22% of a mixture of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:23:8, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 20% to about 23% diisopropyl sebacate, dioctyl carbonate and decyl cocoate A mixture of, for example, about 21% to about 22% of a mixture of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 24% to about 28% diisopropyl sebacate, dioctyl carbonate and decyl cocoate , for example, a mixture of about 25% to about 27% of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 24% to about 28% diisopropyl sebacate, dioctyl carbonate and decyl cocoate , for example, a mixture of about 25% to about 27% of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 23% to about 26% diisopropyl sebacate, dioctyl carbonate and decyl cocoate , for example, a mixture of about 24% to about 25% of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7, and

wherein the composition further comprises dibutyl adipate and decyl cocoate, such as about 31% to about 34% of a mixture of dibutyl adipate and decyl cocoate, for example, about 32% to about 33% A mixture of dibutyl adipate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 23% to about 26% diisopropyl sebacate, dioctyl carbonate and decyl cocoate , for example, a mixture of about 24% to about 25% of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8, and

wherein the composition further comprises diisopropyl sebacate, decyl cocoate and diisopropyl adipate, such as about 25% to about 28% diisopropyl sebacate, decyl cocoate and adipate A mixture of diisopropyl acid, for example, a mixture of about 26% to about 27% of diisopropyl sebacate, decyl cocoate, and diisopropyl adipate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8, and

wherein the composition further comprises diisopropyl sebacate, decyl cocoate and diisopropyl adipate, such as about 25% to about 28% diisopropyl sebacate, decyl cocoate and adipate A mixture of diisopropyl acid, for example, a mixture of about 26% to about 27% of diisopropyl sebacate, decyl cocoate, and diisopropyl adipate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:16:8, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 24% to about 27% diisopropyl sebacate, dioctyl carbonate and decyl cocoate A mixture of, for example, about 25% to about 26% of a mixture of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:14:8, and

Wherein the composition further comprises dibutyl adipate, such as about 36% to about 39% dibutyl adipate, eg, about 37% to about 38% dibutyl adipate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:16:8, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 24% to about 27% diisopropyl sebacate, dioctyl carbonate and decyl cocoate A mixture of, for example, about 25% to about 26% of a mixture of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:16:8, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 25% to about 28% diisopropyl sebacate, dioctyl carbonate and decyl cocoate A mixture of, for example, about 26% to about 27% of a mixture of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:14:8, and

wherein the composition further comprises dibutyl adipate and decyl cocoate, such as about 31% to about 34% of a mixture of dibutyl adipate and decyl cocoate, for example, about 32% to about 33% A mixture of dibutyl adipate and decyl cocoate.

In certain embodiments, sunscreen compositions include:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:15:8, and

wherein the composition further comprises diisopropyl sebacate, dioctyl carbonate and decyl cocoate, such as about 25% to about 28% diisopropyl sebacate, dioctyl carbonate and decyl cocoate A mixture of, for example, about 26% to about 27% of a mixture of diisopropyl sebacate, dioctyl carbonate and decyl cocoate.

In certain embodiments, the sunscreen composition is an emulsion. In certain embodiments, the composition is an oil-in-water emulsion. In certain embodiments, the composition is a water-in-oil emulsion. In certain embodiments, the sunscreen composition is a spray. In certain embodiments, the sunscreen composition is an oil. In certain embodiments, the sunscreen composition is a lotion. In certain embodiments, the sunscreen composition is a cream. In certain embodiments, the sunscreen composition is a gel. In certain embodiments, the sunscreen composition is butter. In certain embodiments, the sunscreen composition is a paste. In certain embodiments, the sunscreen composition is an ointment. In certain embodiments, the sunscreen composition is a stick. In certain embodiments, the sunscreen composition is a powder. In certain embodiments, the sunscreen composition is a wipe. In certain embodiments, the sunscreen composition is a towel. In certain embodiments, the sunscreen composition is a body wash. In certain embodiments, the sunscreen composition is a shampoo. In certain embodiments, the sunscreen composition is a mist. In certain embodiments, the sunscreen composition is a pour-on compact. In certain embodiments, the sunscreen composition is a solution. In certain embodiments, the sunscreen composition is an ointment. In certain embodiments, the sunscreen composition is a liquid. In certain embodiments, the sunscreen composition is a solid. In certain embodiments, the sunscreen composition is an emulsion. In certain embodiments, the sunscreen composition is a suspension. In certain embodiments, the sunscreen composition is a microemulsion. In certain embodiments, the sunscreen composition is a dispersion. In certain embodiments, the sunscreen composition is a microencapsulated product. In certain embodiments, the sunscreen composition is a cream. In certain embodiments, the sunscreen composition is a supplement. In certain embodiments, the sunscreen composition is a paste. In certain embodiments, the sunscreen composition is a skin formulation. In certain embodiments, the sunscreen composition is a soap. In certain embodiments, the sunscreen composition is an aerosol. In certain embodiments, the sunscreen composition is a mousse. In certain embodiments, the sunscreen composition is a wax. In certain embodiments, the sunscreen composition is a hair cream. In certain embodiments, the sunscreen composition is a spritz. In certain embodiments, the sunscreen composition is Japan lacquer. In certain embodiments, the sunscreen composition is a serum. In certain embodiments, the sunscreen composition is a powder. In certain embodiments, the sunscreen composition is a pencil. In certain embodiments, the sunscreen composition is a rouge. In certain embodiments, the sunscreen composition is a highlighter. In certain embodiments, the sunscreen composition is a makeup powder. In certain embodiments, the sunscreen composition is a concealer.

The vehicle may include an aqueous phase, an oil phase, an alcohol, a silicone phase, or a mixture thereof. Cosmetically acceptable vehicles can also include emulsions. Non-limiting examples of suitable emulsions include water-in-oil emulsions, oil-in-water emulsions, silicone-in-water emulsions, water-in-silicone emulsions, wax-in-water emulsions, oil-in-water emulsions that have the appearance of creams, gels, or microemulsions Water-inclusive triple emulsion, etc. Emulsions may contain emulsifiers such as nonionic, anionic or amphoteric surfactants.

In one embodiment, the oily phase of the emulsion has one or more organic compounds, including emollients; humectants (eg, butylene glycol, propylene glycol, methylglucitol-20, and glycerol); other water-dispersible or Water-soluble components, including thickeners such as veegum or hydroxyalkyl cellulose; gelling agents such as high MW polyacrylic acid, ie, CARBOPOL 934; and mixtures thereof. Emulsions may have one or more emulsifiers capable of emulsifying the various components present in the composition.

Compounds suitable for use in the oil phase include, but are not limited to: vegetable oils; esters such as octyl palmitate, isopropyl myristate and isopropyl palmitate; ethers such as dioctyl ether; fatty alcohols such as cetyl alcohol, hard Aliphatic alcohols and phenethyl alcohol; isoparaffins such as isooctane, isododecane and isohexadecane; silicone oils such as dimethylsiloxane, cyclic silicones and polysiloxanes; hydrocarbon oils such as Mineral oils, paraffin oils, isoeicosane, and polyisobutylene; natural or synthetic waxes; and the like. Suitable hydrophobic hydrocarbon oils may be saturated or unsaturated, have aliphatic character and be linear or branched or contain alicyclic or aromatic rings. The oily phase may consist of a single oil or a mixture of different oils.

Hydrogen oils include those hydrocarbon oils having 6-20 carbon atoms, and in one embodiment, more than 10-16 carbon atoms. Representative hydrocarbons include decane, dodecane, tetradecane, tridecane, and _C8-20 isoparaffins. Paraffinic hydrocarbons are available from Exxon under the ISOPARS trademark and from Permethyl Corporation. In addition, _C8-20 paraffinic hydrocarbons such as the C12 isoparaffin (isododecane) manufactured by Permethyl Corporation under the trade name Permethyl _99A.TM. are also envisaged as suitable. Commercially available C16 _isoparaffins such as isohexadecane (with the trade name Permethyl) are also suitable. In one embodiment, examples of volatile hydrocarbons include polydecanes such as isododecane and isodecane, including, for example, Permethyl-99A ( _Presperse Inc.) and C7 _- C8 to _{C12- C15} isoparaffins, such as the Isopar series available from ExxonMobil Chemical Company. A representative hydrocarbon solvent is isododecane.

The oily phase may include one or more waxes including, for example, rice bran wax, galopa wax, copra wax, candelilla wax, montan wax, sugar cane wax, ozokerite wax, polyethylene wax, Fischer-Tropsch wax. Tropsch wax), beeswax, microcrystalline wax, silicone wax, fluorinated wax, and any combination thereof.

Non-limiting emulsifiers include emulsifying waxes, emulsifying polyols, polyether polyols, polyethers, polyols of mono- or diesters, ethylene glycol monostearate, glycerol monostearate, glyceryl distearate Acid esters, silicone-containing emulsifiers, soy alcohol, fatty alcohols such as cetyl alcohol, acrylates, fatty acids such as stearic acid, fatty acid salts, and mixtures thereof. In one embodiment, the emulsifier comprises soy sterol, cetyl alcohol, stearic acid, emulsifying wax, acrylates, silicone-containing emulsifiers, and mixtures thereof. Other specific emulsifiers that can be used in the compositions of the present invention include, but are not limited to, one or more of the following: C _10-30 Alkyl Acrylate Crosspolymer; Dimethicone PEG-7 Isohard Fatty acid, acrylamide copolymer; mineral oil; sorbitol ester; polyglycerol-3-diisostearate; sorbitan monostearate, sorbitol tristearate, sorbitol Hemioleate, sorbitan monooleate; glycerol esters, such as glycerol monostearate and glycerol monooleate; polyoxyethylene phenols, such as polyoxyethylene octylphenol and polyoxyethylene nonylphenol; Polyoxyethylene ethers, such as polyoxyethylene cetyl ether and polyoxyethylene stearyl ether; polyoxyethylene glycol esters; polyoxyethylene sorbitan esters; dimethicone copolyols; polyglycerol esters, such as polyglycerol-3-diisostearate; glyceryl laurate; steareth-2, steareth-10, and steareth-20, to name a few. Additional emulsifiers are provided in the INCI Ingredient Dictionary and Handbook, 11th Edition 2006, the disclosure of which is incorporated herein by reference.

These emulsifiers will generally be in an amount of about 0.001% to about 10% by weight, specifically about 0.01% to about 5% by weight, and more specifically about 0.1% to about 3% by weight in one embodiment present in the composition.

The oil phase may include one or more volatile and/or non-volatile silicone oils. Volatile silicones include cyclic and linear volatile dimethylsiloxane silicones. In one embodiment, the volatile silicone may comprise cyclomethicones, including tetramer (D4 ₎ , pentamer ( _D5 and hexamer ( _D6 ) cyclomethicones or Mixtures thereof. Particular mention is made of volatile cyclomethicone-hexamethylcyclotrisiloxane, octamethyl-cyclotetrasiloxane and decamethyl-cyclopentasiloxane. Suitable dimethylsiloxane Oxanes are available from Dow Corning under the name Dow Corning 200 Fluid and have viscosities ranging from 0.65 to 600,000 centistokes or higher. Exemplary non-polar volatile liquid silicone oils are disclosed in US Pat. No. 4,781,917, where Said U.S. patent is hereby incorporated by reference in its entirety. Additional volatile silicone materials are described in Todd et al., "Volatile Silicone Fluids for Cosmetics", Cosmetics and Toiletries, vol. 91:27-32 (1976), which is hereby incorporated by reference in its entirety. Linear volatile silicones typically have a viscosity of less than about 5 centistokes at 25°C, while cyclic silicones have a viscosity of 25 Less than about 10 centistokes at C. Examples of volatile silicones of different viscosities include Dow Corning 200, Dow Corning 244, Dow Corning 245, Dow Corning 344 and Dow Corning 345 (Dow Corning Corporation); SF-1204 and SF-1202 silicones Fluid (GE Silicones), GE 7207 and 7158 (GE); and SWS-03314 (SWS Silicones Corp.). Linear volatile silicones include low molecular weight polydimethylsiloxanes Oxane compounds, such as hexamethyldisiloxane, octamethyltrisiloxane, decamethyltetrasiloxane, and dodecamethylpentasiloxane, to name a few.

Non-volatile silicone oils will generally include polyalkylsiloxanes, polyarylsiloxanes, polyalkylarylsiloxanes, or mixtures thereof. In one embodiment, the polydimethylsiloxane is a non-volatile silicone oil. The viscosity of the non-volatile silicone oil is typically from about 10 centistokes to about 60,000 centistokes at 25°C, in one embodiment between about 10 centistokes and about 10,000 centistokes, and in one embodiment still More are between about 10 centistokes and about 500 centistokes; and their boiling points are greater than 250°C at ambient pressure. Non-limiting examples include dimethylpolysiloxane (dimethylsiloxane), phenyltrimethicone, and diphenyldimethylsiloxane. Volatile and non-volatile silicone oils can be optionally substituted with various functional groups such as alkyl, aryl, amine, vinyl, hydroxyl, haloalkyl, alkylaryl, and acrylate, to name a few .

Water-in-silicone emulsions can be emulsified with nonionic surfactants (emulsifiers), such as polydiorganosiloxane-polyoxyalkylene block copolymers, including those disclosed in US Pat. No. 4,122,029, which The disclosures of the US patents are incorporated herein by reference. These emulsifiers typically comprise a polydiorganosiloxane backbone, typically a polydimethylsiloxane with side chains comprising -(EO)m- and/or -(PO)n- groups, where EO is ethylene oxy, and PO is 1,2-propenyloxy, the side chain is typically capped or terminated with hydrogen or lower alkyl (eg, C _1-6 , typically C _1-3 ). Other suitable water-in-silicone emulsifiers are disclosed in US Patent No. 6,685,952, the disclosure of which is incorporated herein by reference. Commercially available water-in-silicone emulsifiers include: those available from Dow Corning Corporation under the trade designations 3225C and 5225C FORMULATIONAID; SILICONE SF-1528, available from General Electric Company; ABIL EM 90 and EM 97 available from Hopewell, Va.); and SILWET emulsifier series sold by Compton Co. Ltd. Silicones Division (OSI Specialties).

Examples of water-in-silicone emulsifiers include, but are not limited to, dimethicone PEG 10/15 crosspolymer, dimethicone copolyol, cetyl dimethicone copolyol, PEG- 15 Lauryl Dimethicone Crosspolymer, Lauryl Methicone Crosspolymer, Cyclomethicone and Dimethicone Copolyol, Dimethicone Copolyol (and) Octyl Triglyceride/Capric Triglyceride, Polyglyceryl-4 Isostearate (and) Cetyl Dimethicone Copolyol (and) Hexyl Laurate and Dimethicone Alkyl copolyol (and) cyclopentasiloxane. In one embodiment, examples of water-in-silicone emulsifiers include, but are not limited to, PEG/PPG-18/18 Dimethicone (Dow Corning 5225C), PEG/PPG-19/19 Dimethicone Oxane (Dow Corning Company trade name BY25-337), Cetyl PEG/PPG-10/1 Dimethicone (Goldschmidt Chemical Corporation trade name Abil EM-90), PEG-12 Dimethicone Siloxane (General Electric trade name SF 1288), Lauryl PEG/PPG-18/18 methylsiloxane (Dow Corning trade name 5200FORMULATION AID), PEG-12 Dimethicone Cross-linked polymer (Dow Corning's trade name 9010 and 9011 silicone elastomer blend), PEG-10 dimethylsiloxane cross-polymer (Shin-Etsu trade name KSG-20), Dimethicone PEG-10/15 Crosspolymer (Shin-Etsu Co., Ltd. trade name KSG-210) and Dimethicone PEG-7 Isostearate.

The water-in-silicone emulsifier will generally be present in the composition in an amount from about 0.001 wt% to about 10 wt%, specifically in an amount from about 0.01 wt% to about 5 wt%, and more specifically less than 1 wt%.

The aqueous phase of the emulsion may contain one or more additional solvents, including lower alcohols such as ethanol, isopropanol, and the like. Volatile solvents can also be cosmetically acceptable esters such as butyl acetate or ethyl acetate; ketones such as acetone or ethyl methyl ketone; and the like.

The oily phase will generally comprise from about 10% to about 99% by weight, in one embodiment from about 20% to about 85% by weight, and more in one embodiment about 30% by weight, based on the total weight of the emulsion to about 70% by weight of the total emulsion, and the aqueous phase will generally comprise from about 1% to about 90% by weight, in one embodiment from about 5% to about 70% by weight, and more in one embodiment about 20% to about 60% by weight of the total emulsion. The aqueous phase will typically comprise from about 25% to about 100% by weight, more typically from about 50% to about 95% by weight water.

The composition may contain liposomes. Liposomes may include other additives or substances, and/or may be modified to more specifically reach or remain at a certain site after administration.

The composition may optionally include other cosmetic actives and excipients apparent to those skilled in the art including, but not limited to, fillers, emulsifiers, antioxidants, Surfactants, film formers, chelating agents, gelling agents, thickeners, emollients, humectants, moisturizers, vitamins, minerals, viscosity and/or rheology modifiers, sunscreens, keratinizers, depigmentation agent, retinol, hormonal compound, alpha-hydroxy acid, alpha-keto acid, antimycobacterial, antifungal, antimicrobial, antiviral, analgesic, lipid compound, antiallergic, H1 or H2 Antihistamines, Anti-Inflammatories, Anti-Irritants, Antineoplastics, Immune System Enhancers, Immune System Suppressants, Antiacinar Agents, Anesthetics, Antimicrobials, Insect Repellents, Skin Cooling Compounds, Skin Care Agents, Skin Penetration Enhancers, exfoliants, lubricants, fragrances, colorants, depigmentation agents, hypopigmentation agents, preservatives (eg, DMDM hydantoin/iodopropynyl butyl carbonate), stabilizers, pharmaceutical preparations, light Stabilizers, neutralizers (eg, triethanolamine), and mixtures thereof. In addition to the foregoing, the cosmetic compositions of the present invention may contain any other compound useful in the treatment of skin disorders.

Examples of film formers include poly C10-30 alkyl acrylates and triethylpentanediol/adipic acid/glycerol crosspolymers.

In certain embodiments, sunscreen compositions may also include other cosmetic ingredients such as, but not limited to, humectants, emollients, moisturizers, anti-wrinkle ingredients, concealers, matte polishes, pigments, colorants, proteins , Antioxidant, Toning Powder, Chelating Agent, Emulsifier, Ultraviolet (UV) Absorber, Oil Absorber, Antifoaming Agent, Antisticking Agent, Thickening Agent, Fragrance, Preservative, Antimicrobial, Fungicide, Neutralizers, vitamins, plasticizers, cohesives, alkalizing and acidifying agents, fillers, solvents and mixtures thereof. It will be understood by those skilled in the art that any other cosmetically acceptable ingredients, ie, those contained in the CFTA Cosmetic Ingredient Dictionary, 3rd Edition, may be used.

The compositions may contain additional ingredients such as alkalizing agents, emulsifiers, emollients, plasticizers, preservatives, humectants, humectants, solvents and tonicity agents or active ingredients suitable for providing anti-aging benefits. An example of a preferred additional ingredient includes glycerin. Thickening agents such as gelling agents can also be used. Examples include bentone, triglycerides, aluminum stearate, C18-C36 acid glycol esters, glyceryl tribehenate, glyceryl monostearate, alginate, carbomer, cellulose, gum, carrageenan, starch or silicate. Fillers may also optionally be added in an amount of about 1% to about 20%, preferably about 1% to about 10%. Examples of fillers include silica, PMMA, nylon, alumina, barium sulfate, or any other filler commonly used in such compositions.

The composition may also contain at least one cosmetic active ingredient and/or at least one dermatological active ingredient, ie an agent having a beneficial effect on the skin. Loading of such active ingredients can be accomplished in any manner known to those skilled in the art. The composition may include other whitening or lightening agents further including pigments or other reflective materials to hide the discoloration or treat the cause of the discoloration.

In certain embodiments, the sunscreen composition is substantially stable to sunlight. In certain embodiments, the AUC in the spectral absorption spectrum after irradiation with the solar simulator is at least 80% of the AUC in the spectral absorption spectrum before irradiation. The AUC in the spectral absorption spectrum after irradiation with the solar simulator is at least 90% of the AUC in the spectral absorption spectrum before irradiation. Solar stability can be measured by methods known to those skilled in the art.

In certain embodiments, the sunscreen composition is substantially waterproof. Water repellency can be measured by methods known to those skilled in the art. In certain embodiments, the composition is waterproof within 40 or 80 minutes, as described by the US Food and Drug Administration in Vol. 21 of the Code of Federal Regulations (2019) Encoded in Section 201.327(i)(7).

In certain embodiments, the sunscreen composition is phase stable. As used herein, "phase stability" means maintaining interfacial stability or suspension stability, or both, for at least 4 weeks at each temperature of 4°C, 32-37°C, 40-45°C, 25°C. "Interfacial stability" refers to stability to coalescence and roughening of discontinuous phases in compositions having two or more phases. "Suspension stability" refers to stability to creaming and/or precipitation of a discontinuous phase, eg, solids suspended in a continuous phase.

In certain embodiments, the sunscreen composition maintains interfacial stability and suspension stability for at least 4 weeks at each of 4°C, 32-37°C, 40-45°C, 25°C. To assess such stability conditions, the composition can be filled into an appropriately sized container, such as a clear 4 ounce glass jar, where the composition is fully visible.

The interfacial stability of a sunscreen composition can be assessed visually and is considered unstable if at least two different immiscible phases of the composition are observed, as is well known in the art.

In certain embodiments, the sunscreen composition is not phase stable and, for example, shakes before use.

Also as known in the art, the suspension stability of a sunscreen composition can be assessed visually or tactilely, and if a color difference is observed between different areas of the sample (ie, top and bottom or other different areas) Other indicators of different segregation or gradient, opacity, brittleness or inhomogeneity, the suspension stability is considered unstable. Alternatively, the suspension stability of the composition can be assessed by, but not limited to, Brookfield viscosity, and if there are significant differences in viscosity measurements between different regions in the sample (ie, top and bottom or other change (eg, 5% or 10% or 20%), the suspension stability is considered unstable. Brookfield viscosity can be measured with a Brookfield laboratory viscometer from AMETEK Inc. (AMETEK Inc., Middleboro, Mass.) using settings, spindles and speeds appropriate to the viscosity of the composition.

Overall phase stability can also be assessed by other techniques known in the art, for example, by analytical chemistry testing for significant changes in chemical composition determined between different regions (ie, top and bottom or other different regions) in a sample .

Sunscreen compositions can be used by topical application to the skin. Methods for application may comprise spraying, smearing, wiping or applying the composition directly to the skin.

Sunscreen compositions can be prepared using mixing and blending methods well established in the sunscreen and cosmetic arts. In one embodiment, the composition is produced by: preparing the oil phase by mixing the UV absorbing compound with optional oil-soluble or oil-miscible ingredients; and by mixing water with optional water-soluble or water-miscible ingredients Mix to prepare the aqueous phase. The oil phase and the water phase can then be mixed in a manner sufficient to disperse the oil phase substantially uniformly in the water phase such that the water phase is persistent and the oil phase is not.

The weight percent of the aqueous phase included in the composition may range from about 30% to about 85%, such as about 35% to about 75%, such as about 40% to about 70%. The percentage of water by weight in the aqueous phase can be about 60% or greater, such as about 70% or greater, such as about 90% or greater.

The composition may be combined with a "cosmetically acceptable topical carrier", that is, a carrier for topical use which can contain other ingredients dispersed or dissolved therein and has acceptable properties that make it safe for topical use combination.

Cosmetically acceptable topical carriers can optionally include various additional oil-soluble and/or water-soluble materials conventionally employed in compositions for use in the skin at levels established in the art. For example, surfactants, emulsifiers, beading or opacifying agents, thickeners, emollients, conditioners, humectants, chelating agents, exfoliants, preservatives, pH adjusters and enhance the appearance of the composition , sensory or fragrance additives such as colorants, fragrances, tactile modifiers, etc. may be included.

In certain embodiments, the composition comprises pigments suitable for providing color or hiding power. The pigment may be one of those suitable for color cosmetic products, including compositions for application to hair, nails and/or skin, especially the face. Color cosmetic compositions include, but are not limited to, foundation, concealer, primer, rouge, mascara, eye shadow, eyeliner, lipstick, nail polish, and tinted moisturizer. Pigments suitable for providing color or hiding power may consist of iron oxides including red and yellow iron oxides, titanium dioxide, ultra-ocean and chromium or chromium hydroxide colors and mixtures thereof. Pigments may be lake pigments precipitated onto inert binders such as insoluble salts, such as organic dyes such as azo, indigo, triphenylmethane, anthraquinone and are designated D&C and FD&C blue, brown, green, Xanthine dyes of orange, red, yellow, etc. Examples of lake pigments include red #6, red #7, yellow #5, violet #2, and blue #1. The pigments may be coherent pigments. Examples of coherent pigments include those containing mica substrates, bismuth oxychloride substrates, and silica substrates, such as mica/bismuth oxychloride/iron oxide commercially available as CHROMALITE pigments (BASF). Pigments, titanium dioxide and/or iron oxides such as commercially available FLAMENCO pigments (BASF) coated on mica, including commercially available KTZ pigments (Kobo products), CELLINI pearl pigments ( BASF) and mica/titanium dioxide/iron oxide pigments containing borosilicate pigments such as REFLECKS pigments (BASF).

In one embodiment, the composition includes a humectant, such as glycol, glycerol, or propylene glycol. The composition may include, for example, at least about 1.0% by weight of a humectant.

The composition may further include one or more other cosmetically acceptable active agents, including, for example, anti-acne agents, oil control agents, antimicrobial agents, anti-mycotic agents, anti-parasitic agents (including anti-monkey venom), external analgesics , Antioxidants, Moisturizers, Nutrients, Vitamins, Energy Boosters, Antiperspirants, Astringents, Deodorants, Firming Agents, Anticocooning Agents and Agents for Skin Conditioning, Tanning Agents, Anti-Wrinkle and Anti-Darkness spot.

In certain embodiments, the compositions are intended for use as a non-therapeutic treatment. In certain embodiments, the composition is intended to be rubbed, poured, sprayed, or sprayed onto, introduced into, or otherwise applied to the human body in accordance with the US FD&C Act, §201(i) Articles applied to the human body for cleaning, beautifying, enhancing attractiveness or changing appearance.

The amount of the other cosmetic active agent may range from about 0.001% to about 20% by weight of the composition, such as from about 0.005% to about 10% by weight of the composition, such as from about 0.01% to about 5% by weight of the composition .

According to some aspects, the sunscreen formulations described herein are ecologically comparable compositions. For example, sunscreen formulations may be compatible with biological life and not harmful to marine ecosystems, especially tropical environments with coral reefs. Specifically, sunscreen formulations do not contain components that inhibit cell growth or cell replication in the marine environment. In some examples, this can be achieved with the following sunscreen formulations: free of bis-ethylhexyloxyphenol methoxyphenyl triazine (BEMT), cinnamate, benzophenone, camphor derivatives, titanium oxide, tea tree Essential Oil, Ylang Ylang Flower Extract, Bambousa Arundinacea Extract, Shea Butter (Karitè), Fats of Animal Origin, Ali Root Oil, Tocopherol Acetate, Tocopherol, Retinol, From Green Tea Extracted polyphenolic compounds or mixtures thereof. In some aspects, a sunscreen formulation can include diisopropyl sebacate, dimethylmethoxychromanol, gluconolactone, potassium sorbate, dimethylmethoxybenzoate Dihydropyranol, decyl cocoate, pentanediol, dimethicone, hydrolyzed citrus aurantium fruit extract.

Exemplary aspects.

The following exemplary embodiments are provided, the numbering of which should not be construed as specifying levels of importance:

Aspect 1 provides a UV filter composition comprising:

Three UV-B filters;

UV-A filters; and

UV-A+UV-B broadband filter.

Aspect 2 provides a sunscreen composition comprising the UV filter composition of Aspect 1.

Aspect 3 provides the sunscreen composition of aspect 2, comprising one or more solubilizers.

Aspect 4 provides the sunscreen composition according to aspect 3, wherein the one or more solubilizers are selected from the group consisting of: diisopropyl sebacate, dioctyl carbonate, decyl cocoate, adipic acid Diisopropyl, isopropyl lauroyl sarcosine, dibutyl adipate, butyl octyl salicylate, C12-15 alkyl benzoate and diethylhexyl succinate.

Aspect 5 provides the sunscreen composition of any one of aspects 2 to 4, wherein:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenolmethoxyphenyltriazine.

Aspect 6 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:1.

Aspect 7 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:11:2.

Aspect 8 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:13:2.

Aspect 9 provides the sunscreen composition of any one of aspects 2 to 4, wherein:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenolmethoxyphenyltriazine.

Aspect 10 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:5.5:1.

Aspect 11 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:11:2.

Aspect 12 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:13:2.

Aspect 13 provides the sunscreen composition of any one of aspects 2 to 4, wherein:

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenolmethoxyphenyltriazine.

Aspect 14 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:1.

Aspect 15 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:3:1.

Aspect 16 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:13:2.

Aspect 17 provides the sunscreen composition of any one of aspects 2 to 16, wherein the one or more solubilizers are diisopropyl sebacate.

Aspect 18 provides the sunscreen composition of aspect 17, wherein the composition comprises from about 8% to about 10% diisopropyl sebacate.

Aspect 19 provides the sunscreen composition of aspect 18, wherein the composition comprises from about 6% to about 8% diisopropyl sebacate.

Aspect 20 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4.

Aspect 21 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4.

Aspect 22 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 6:17:4.

Aspect 23 provides the sunscreen composition of any one of aspects 22 to 24, wherein the one or more solubilizers are diisopropyl sebacate and dioctyl carbonate.

Aspect 24 provides the sunscreen composition of aspect 25, wherein the composition comprises about 13% to about 15.5% of a mixture of diisopropyl sebacate and dioctyl carbonate.

Aspect 25 provides the sunscreen composition of aspect 26, wherein the composition comprises about 13.5% to about 15% of a mixture of diisopropyl sebacate and dioctyl carbonate.

Aspect 26 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:13:6.

Aspect 27 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:17:6.

Aspect 28 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:13:6.

Aspect 29 provides the sunscreen composition of any one of aspects 26 to 28, wherein the one or more solubilizers are decyl cocoate, isopropyl lauroyl sarcosine, and diadipate Butyl ester.

Aspect 30 provides the sunscreen composition of aspect 29, wherein the composition comprises from about 16% to about 18% of decyl cocoate, isopropyl lauroyl sarcosine, and dibutyl adipate mixture.

Aspect 31 provides the sunscreen composition of aspect 30, wherein the composition comprises from about 16.5% to about 17.5% of decyl cocoate, isopropyl lauroyl sarcosine, and dibutyl adipate mixture.

Aspect 32 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:2:1.

Aspect 33 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 3:8.5:2.

Aspect 34 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 1:2:1.

Aspect 35 provides the sunscreen composition of any one of aspects 32 to 34, wherein the one or more solubilizers are decyl cocoate and diisopropyl sebacate.

Aspect 36 provides the sunscreen composition of aspect 35, wherein the composition comprises about 19% to about 21% of a mixture of decyl cocoate and diisopropyl sebacate.

Aspect 37 provides the sunscreen composition of aspect 36, wherein the composition comprises about 19.5% to about 20.5% of a mixture of decyl cocoate and diisopropyl sebacate.

Aspect 38 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:13:6.

Aspect 39 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:11:6.

Aspect 40 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 7:11:6.

Aspect 41 provides the sunscreen composition of any one of aspects 38 to 40, wherein the one or more solubilizers are diisopropyl sebacate, dioctyl carbonate, and decyl cocoate .

Aspect 42 provides the sunscreen composition of aspect 41, wherein the composition comprises from about 19.5% to about 21.5% of a mixture of diisopropyl sebacate, dioctyl carbonate, and decyl cocoate.

Aspect 43 provides the sunscreen composition of aspect 42, wherein the composition comprises about 20% to about 21% of a mixture of diisopropyl sebacate, dioctyl carbonate, and decyl cocoate.

Aspect 44 provides the sunscreen composition of any one of aspects 38 to 40, wherein the one or more solubilizers are diisopropyl sebacate, decyl cocoate, and lauroyl sarcosine isopropyl acid.

Aspect 45 provides the sunscreen composition of aspect 44, wherein the composition comprises from about 16% to about 18% of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosine a mixture of esters.

Aspect 46 provides the sunscreen composition of aspect 45, wherein the composition comprises from about 16.5% to about 17.5% of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosine a mixture of esters.

Aspect 47 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8.

Aspect 48 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:4:8.

Aspect 49 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:24:8.

Aspect 50 provides the sunscreen composition of any one of aspects 47 to 49, wherein the one or more solubilizers are diisopropyl sebacate, dioctyl carbonate, and decyl cocoate .

Aspect 51 provides the sunscreen composition of aspect 5, wherein the composition comprises about 25% to about 29% of a mixture of diisopropyl sebacate, dioctyl carbonate, and decyl cocoate.

Aspect 52 provides the sunscreen composition of aspect 51, wherein the composition comprises about 26% to about 28% of a mixture of diisopropyl sebacate, dioctyl carbonate, and decyl cocoate.

Aspect 53 provides the sunscreen composition of any one of aspects 47 to 51, wherein the one or more solubilizers are diisopropyl sebacate and diisopropyl adipate.

Aspect 54 provides the sunscreen composition of aspect 53, wherein the composition comprises about 32.5% to about 35/5% of a mixture of diisopropyl sebacate and diisopropyl adipate.

Aspect 55 provides the sunscreen composition of aspect 54, wherein the composition comprises about 33% to about 35% of a mixture of diisopropyl sebacate and diisopropyl adipate.

Aspect 56 provides the sunscreen composition of any one of aspects 47 to 49, wherein the one or more solubilizers are diisopropyl sebacate, decyl cocoate, and lauroyl sarcosine isopropyl acid.

Aspect 57 provides the sunscreen composition of aspect 56, wherein the composition comprises from about 22.5% to about 25.5% of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosine a mixture of esters.

Aspect 58 provides the sunscreen composition of aspect 57, wherein the composition comprises about 23% to about 25% diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosine a mixture of esters.

Aspect 59 provides the sunscreen composition of any one of aspects 47 to 49, wherein the one or more solubilizers are decyl cocoate, isopropyl lauroyl sarcosine, and diadipate Butyl ester.

Aspect 60 provides the sunscreen composition of aspect 59, wherein the composition comprises from about 28% to about 31% of decyl cocoate, isopropyl lauroyl sarcosine, and dibutyl adipate mixture.

Aspect 61 provides the sunscreen composition of aspect 60, wherein the composition comprises from about 29% to about 3-% of decyl cocoate, isopropyl lauroyl sarcosine, and dibutyl adipate a mixture of esters.

Aspect 62 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8.

Aspect 63 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8.

Aspect 64 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:19:8.

Aspect 65 provides the sunscreen composition of any one of aspects 62 to 64, wherein the one or more solubilizers are diisopropyl sebacate, decyl cocoate, and lauroyl sarcosine isopropyl acid.

Aspect 66 provides the sunscreen composition of aspect 65, wherein the composition comprises from about 18% to about 22% of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosine a mixture of esters.

Aspect 67 provides the sunscreen composition of aspect 66, wherein the composition comprises about 20% to about 21% diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosine a mixture of esters.

Aspect 68 provides the sunscreen composition of any one of aspects 62 to 64, wherein the one or more solubilizers are diisopropyl sebacate, diisopropyl adipate, and coconut oil Decyl acid.

Aspect 69 provides the sunscreen composition of aspect 68, wherein the composition comprises about 29% to about 33% diisopropyl sebacate, diisopropyl adipate, and decyl cocoate mixture.

Aspect 70 provides the sunscreen composition of aspect 69, wherein the composition comprises from about 30% to about 32% diisopropyl sebacate, diisopropyl adipate, and decyl cocoate mixture.

Aspect 71 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:17:8.

Aspect 72 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7.

Aspect 73 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:17:8.

Aspect 74 provides the sunscreen composition of any one of aspects 71 to 73, wherein the one or more solubilizers are diisopropyl sebacate, diisopropyl adipate, and coconut oil Decyl acid.

Aspect 75 provides the sunscreen composition of aspect 74, wherein the composition comprises from about 25% to about 2827% diisopropyl sebacate, diisopropyl adipate, and decyl cocoate mixture.

Aspect 76 provides the sunscreen composition of aspect 75, wherein the composition comprises about 26% to about 27% diisopropyl sebacate, diisopropyl adipate, and decyl cocoate mixture.

Aspect 77 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:25:7.

Aspect 78 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:25:7.

Aspect 79 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:25:7.

Aspect 80 provides the sunscreen composition of any one of aspects 77-79, wherein the one or more solubilizers are diisopropyl sebacate and dioctyl carbonate.

Aspect 81 provides the sunscreen composition of aspect 80, wherein the composition comprises from about 17% to about 20% of a mixture of diisopropyl sebacate and dioctyl carbonate.

Aspect 82 provides the sunscreen composition of aspect 81, wherein the composition comprises from about 18% to about 19% of a mixture of diisopropyl sebacate and dioctyl carbonate.

Aspect 83 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:23:8.

Aspect 84 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:23:8.

Aspect 85 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:23:8.

Aspect 86 provides the sunscreen composition of any one of aspects 83 to 85, wherein the one or more solubilizers are diisopropyl sebacate, dioctyl carbonate, and decyl cocoate .

Aspect 87 provides the sunscreen composition of aspect 86, wherein the composition comprises from about 20% to about 23% of a mixture of diisopropyl sebacate, dioctyl carbonate, and decyl cocoate.

Aspect 88 provides the sunscreen composition of aspect 87, wherein the composition comprises about 21% to about 22% of a mixture of diisopropyl sebacate, dioctyl carbonate, and decyl cocoate.

Aspect 89 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8.

Aspect 90 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7.

Aspect 91 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8.

Aspect 92 provides the sunscreen composition of any one of aspects 89 to 91, wherein the one or more solubilizers are dibutyl adipate.

Aspect 93 provides the sunscreen composition of aspect 92, wherein the composition comprises from about 36% to about 39% dibutyl adipate.

Aspect 94 provides the sunscreen composition of aspect 93, wherein the composition comprises from about 37% to about 38% dibutyl adipate.

Aspect 95 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8.

Aspect 96 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:20:7.

Aspect 97 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:18:8.

Aspect 98 provides the sunscreen composition of any one of aspects 94 to 97, wherein the one or more solubilizers are diisopropyl sebacate, dioctyl carbonate, and decyl cocoate .

Aspect 99 provides the sunscreen composition of aspect 98, wherein the composition comprises about 23% to about 26% of a mixture of diisopropyl sebacate, dioctyl carbonate, and decyl cocoate.

Aspect 100 provides the sunscreen composition of aspect 99, wherein the composition comprises about 24% to about 25% of a mixture of diisopropyl sebacate, dioctyl carbonate, and decyl cocoate.

Aspect 101 provides the sunscreen composition of any one of aspects 95 to 97, wherein the one or more solubilizers are diisopropyl sebacate, decyl cocoate, and diisoadipate Propyl ester.

Aspect 102 provides the sunscreen composition of aspect 101, wherein the composition comprises from about 25% to about 28% of diisopropyl sebacate, decyl cocoate, and diisopropyl adipate. mixture.

Aspect 103 provides the sunscreen composition of aspect 102, wherein the composition comprises from about 26% to about 27% of diisopropyl sebacate, decyl cocoate, and diisopropyl adipate. mixture.

Aspect 104 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:155:8.

Aspect 105 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:14:8.

Aspect 106 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:15:8.

Aspect 107 provides the sunscreen composition of any one of aspects 104 to 106, wherein the one or more solubilizers are dioctyl carbonate.

Aspect 108 provides the sunscreen composition of aspect 107, wherein the composition comprises about 26% to about 27% dioctyl carbonate.

Aspect 109 provides the sunscreen composition of aspect 108, wherein the composition comprises about 24% to about 26% dioctyl carbonate.

Aspect 110 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:16:8.

Aspect 111 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:14:8.

Aspect 112 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:16:8.

Aspect 113 provides the sunscreen composition of any one of aspects 110 to 112, wherein the one or more solubilizers are diisopropyl sebacate, dioctyl carbonate, and decyl cocoate .

Aspect 114 provides the sunscreen composition of aspect 113, wherein the composition comprises about 24% to about 27% of a mixture of diisopropyl sebacate, dioctyl carbonate, and decyl cocoate.

Aspect 115 provides the sunscreen composition of aspect 114, wherein the composition comprises about 25% to about 26% of a mixture of diisopropyl sebacate, dioctyl carbonate, and decyl cocoate.

Aspect 116 provides the sunscreen composition of aspect 5, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is isoamyl p-methoxycinnamate; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:15:8.

Aspect 117 provides the sunscreen composition of aspect 9, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is ethylhexyl triazinone;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:14:8.

Aspect 118 provides the sunscreen composition of aspect 13, wherein

The UV-A filter is butylmethoxydibenzoylmethane;

The first UV-B filter is isoamyl p-methoxycinnamate;

The second UV-B filter is octyl salicylate;

The third UV-B filter is diethylhexylbutanamidotriazinone; and

The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenol methoxyphenyltriazine,

The mass ratio of UV-A filter to UV-B filter to broadband filter is about 9:15:8.

Aspect 119 provides the sunscreen composition of any one of aspects 116 to 118, wherein the one or more solubilizers are dibutyl adipate and decyl cocoate.

Aspect 120 provides the sunscreen composition of aspect 119, wherein the composition comprises about 31% to about 34% of a mixture of diisopropyl sebacate, dioctyl carbonate, and decyl cocoate.

Aspect 121 provides the sunscreen composition of aspect 120, wherein the composition comprises about 32% to about 33% of a mixture of diisopropyl sebacate, dioctyl carbonate, and decyl cocoate.

Aspect 122 provides a method for protecting skin from sun damage, the method comprising applying the sunscreen composition of any one of aspects 2 to 121 to the skin.

Example 1

The following formulations can be prepared using methods known in the art.

Table 1: Sunscreen formulations.

Example 2

The following formulations can be prepared using methods known in the art.

Table 2: Sunscreen formulations.

Example 3

The following formulations can be prepared using methods known in the art.

Table 3: Sunscreen formulations.

Example 4

The following formulations can be prepared using methods known in the art.

Table 4: Sunscreen formulations.

Example 5

Prepare a face cream with an SPF of at least 50 in the form of a cream. An oil phase is prepared comprising the UV filter composition as described herein, one or more solubilizers, thickeners, emulsifiers and waxes as described herein. The oil phase is added to the water phase including water and glycerin with mixing. Rheology modifiers, colors, preservatives, fragrances and active ingredients can be added.

Example 6

Various sunscreens are formulated with different concentrations of UV filters. Specifically, three sunscreens each containing a total of five UV filters were developed and compared to sunscreen formulations containing nine UV filters. Formulations are presented below and list the types and concentrations of UV filters.

Table 5: Comparison formula

Table 6: Equation 1

Table 7: Equation 2

Table 8: Equation 3

The sun protection factor (SPF), persistent pigmentation (PPD), and SPF/PPD quotient were compared between Comparative Equations, Equation 1, Equation 2, and Equation 3. The results show that Equation 1, Equation 2 and Equation 3 give equivalent or better performance compared to the comparative equations. Notably, equivalent or better performance is achieved with Equations 1, 2 and 3 with less total filter and lower total concentration of filter in wt %. The results are shown in Figures 1-6.

Figure 1 shows that the in vivo SPF of Formulas 1 and 2 is substantially the same as the SPF of the Comparative Formula. Figure 2 shows that the PPD of Equation 1 is substantially the same as the Comparative Equation. FIG. 3 shows that the SPF/PPD quotient of Equation 1 is substantially the same as the Comparative Equation. Figure 4 shows that the SPF of Equation 3 is improved over the Comparative Equation. Figure 5 shows that the PPD of Equation 3 is substantially the same as the Comparative Equation. FIG. 6 shows that the SPF/PPD quotient of Equation 3 is substantially the same as the Comparative Equation.

All references, patents, or applications cited in this application, whether U.S. or foreign, are hereby incorporated by reference as if incorporated in their entirety. In the event of any inconsistency, the material truly disclosed herein will prevail.

From the foregoing description, one skilled in the art can easily ascertain the essential characteristics of this invention, and without departing from the spirit and scope of the invention, can make various changes and modifications of the invention to adapt it to various usages and conditions.

Claims (16)

1. A UV filter composition comprising: Three UV-B filters; UV-A filters; and UV-A+UV-B broadband filter. 2. A sunscreen composition comprising the UV filter composition of claim 1. 3. The sunscreen composition of claim 2, further comprising one or more solubilizers. 4. The sunscreen composition of claim 3, wherein the one or more solubilizers are selected from the group consisting of: diisopropyl sebacate, dioctyl carbonate, decyl cocoate, diadipate Isopropyl ester, isopropyl lauroyl sarcosine, dibutyl adipate, butyl octyl salicylate, C12-15 alkyl benzoate and diethylhexyl succinate. 5. The sunscreen composition of any one of claims 2 to 4, further comprising one or more emulsifiers. 6. The sunscreen composition of claim 5, wherein the one or more emulsifiers are selected from the group consisting of polyglycerol 6 stearate, polyglycerol 6 behenate, or potassium cetyl phosphate or acrylates Vinyl neodecanoate crosspolymer. 7. The sunscreen composition of any one of claims 2 to 4, wherein The UV-A filter includes butylmethoxydibenzoylmethane; The UV-B filter is selected from the group consisting of ethylhexyl triazinone, octyl salicylate and isoamyl p-methoxycinnamate, diethylhexyl butyramidotriazinone; and The broadband UV-A and UV-B filters include bis-ethylhexyloxyphenolmethoxyphenyltriazine. 8. The sunscreen composition of any one of claims 1 to 7, wherein the UV filter composition comprises: Three UV-B filters; UV-A filters; and UV-A+UV-B broadband filter. 9. The sunscreen composition of any one of claims 2 to 4, wherein: The UV-A filter is butylmethoxydibenzoylmethane, The UV-B filter is ethylhexyl triazinone, octyl salicylate, diethylhexyl butyramido triazinone, and The broadband UV-A and UV-B filters are bis-ethylhexyloxyphenolmethoxyphenyltriazine. 10. The sunscreen composition of claim 5, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 2:7:1. 11. The sunscreen composition of claim 5, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:11:2. 12. The sunscreen composition of claim 5, wherein the mass ratio of UV-A filter to UV-B filter to broadband filter is about 4:13:2. 13. The sunscreen composition of any one of claims 2 to 12, wherein the composition comprises from about 8% to about 10% of a solubilizer. 14. The sunscreen composition of any one of claims 2 to 12, wherein the composition comprises from about 8% to about 10% of a film former. 15. The sunscreen composition of any one of claims 2 to 12, wherein the UV-B filter, UV-A filter, and UV-A+UV-B broadband filter together are The range is from about 5 wt% to about 25 wt% of the sunscreen composition. 16. A method for protecting skin from sun damage, the method comprising applying the sunscreen composition of any one of claims 2 to 14 to the skin.

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