CN1147398A - Chinese patent medicine for treating cirrhosis - Google Patents
Chinese patent medicine for treating cirrhosis Download PDFInfo
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- CN1147398A CN1147398A CN 96109557 CN96109557A CN1147398A CN 1147398 A CN1147398 A CN 1147398A CN 96109557 CN96109557 CN 96109557 CN 96109557 A CN96109557 A CN 96109557A CN 1147398 A CN1147398 A CN 1147398A
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Abstract
A Chinese patent medicine for treating cirrhosis is characterized by comprising the following components: radix bupleuri, radix astragali, carapax et Plastrum Testudinis, carapax Trionycis, rhizoma Cyperi, rhizoma Atractylodis Macrocephalae, rhizoma corydalis, pericarpium Citri Reticulatae viride, radix Angelicae sinensis, radix aucklandiae, radix Paeoniae Rubra, radix Paeoniae alba, rhizoma Sparganii, rhizoma Curcumae, Eupolyphaga Seu Steleophaga, fructus Schisandrae chinensis, Cordyceps, and fructus Aurantii. The dosage forms include pills, capsules, tablets, powder, granules, paste, decoction and the like. The traditional Chinese medicine composition has the positive effects of being applicable to cirrhosis caused by various causes of diseases, having quick response and good and thorough effect in clinical treatment, and preventing relapse after clinical symptoms are eliminated. Has no toxicity or side effects.
Description
The present invention relates to Chinese patent medicine, or rather, relate to a kind of Chinese patent medicine that is used for the treatment of liver cirrhosis.
In all age, liver cirrhosis belongs to one of difficult and complicated illness all the time.The paathogenic factor of liver cirrhosis is extensive, the sickness rate height.The whole nation and spread various viral hepatitis, especially hepatitis B all over the world and be difficult to cure over particularly past 20 years finally has quite a few patient to be transformed into liver cirrhosis.Up to now, in, the western medicine bound pair liver cirrhosis disease ideal medicine that still is of no curative effect.This mainly is the pathological changes mechanism complexity because of liver cirrhosis, and the pathological changes phase shows not obvious clinically, and because the symptom at its initial stage is intricate, feeling of patient is varied, thereby is easy to take place mistaken diagnosis.Up in the state of an illness enters, late period, clinical manifestation just can be diagnosed as liver cirrhosis when outstanding, thereby makes treatment and rehabilitation increase many difficulties.
Modern medicine thinks that liver cirrhosis is because various paathogenic factors act on liver, disturbs and the destruction liver function, causes hepatic necrosis or alienation hypertrophy, develops into liver cirrhosis, causes liver function low and disorderly, until liver failure.Its Therapeutic Method is to protect the liver, to expand blood vessel, hemostasis diuresis, in case of necessity by emergency measures such as surgical ligation blood vessels, so that relief of symptoms suitably prolongs patient's life.But these methods all do not reach the purpose of radical cure.
Chinese medicine is called tympanites with liver cirrhosis, and numerous doctor families are different to the dialectical method of treatment of this disease.Most doctors are tame to think that the formation of tympanites disease is by damp and hot, evil poison infringement liver and gall, brings disaster to taste, causes state of an illness delay, and the liver spleen restrains insult mutually, and extremely blood glue coagulates due to the liver pulse.Generally to set upright conditioning, it is auxilliary that the water of dispelling is attacked heresy.Yet the traditional Chinese medical science prescription and the Chinese patent medicine that also do not have ideal treatment liver cirrhosis so far.
The objective of the invention is to provide a kind of can be rapidly and treat the Chinese patent medicine of liver cirrhosis up hill and dale.
To having done deep observation and research because a variety of causes causes the mechanism of liver cirrhosis and clinical symptoms thereof, theory of Chinese medical science thinks that liver,spleen,kidney three internal organs have the relation of growing mutually and restraining mutually to the inventor according to theory of Chinese medical science.The function of liver is main catharsis, harmonizing the functional activities of vital QI, stored blood; The function of spleen is that main ascending the clear and descending the turbid, transporting and transforming nutrients from foodstuff are precise and tiny; The function of kidney is main warm evaporating, drain water liquid.Liver spleen kidney three internal organs must work in coordination with mutually just can finish qi-blood-body fluid transfer the fortuneization function.Therefore treat liver cirrhosis and must adopt clothes depressed liver-energy dispersing and QI regulating blood circulation promoting and blood stasis dispelling softening the hard mass, the dialectical method of air making-up and spleen enlivening kidney tonifying, with the mediation harmonizing the functional activities of vital QI, dissipation liver blood stasis, promote that venation is unobstructed, improve to strengthen the function that fortuneization and drain water wet of transferring of spleen kidney, thereby can reach softening liver, the purpose of elimination ascites.The inventor is according to this theory, on the basis of secret prescription handed down in the family from generation to generation, cooperate the advanced diagnostic means of modern medicine to carry out secular clinical trial, finally found a kind of liver cirrhosis that is applicable to that treatment is caused by the various causes of disease, and its Chinese medicine preparation and corresponding Chinese patent medicine of thoroughly curing so far just can have been finished the present invention.
Thereby, the invention provides a kind of Chinese patent medicine that is used for the treatment of liver cirrhosis, it is characterized in that it contains following traditional Chinese medicines composition (weight portion):
Radix Bupleuri 20-30, Radix Astragali 30-50, Carapax et Plastrum Testudinis 20-40,
Carapax Trionycis 20-40, Rhizoma Cyperi 20-30, Rhizoma Atractylodis Macrocephalae 30-60,
Rhizoma Corydalis 20-30, Pericarpium Citri Reticulatae Viride 20-30, Radix Angelicae Sinensis 20-30,
Radix Aucklandiae (Radix Vladimiriae) 20-30, Radix Paeoniae Rubra 30-60, Radix Paeoniae Alba 20-30,
Rhizoma sparganic 20-30, Rhizoma Curcumae 20-30, Eupolyphaga Seu Steleophaga 20-30,
Fructus Schisandrae Chinensis 30-50, Cordyceps 5-10, Fructus Aurantii 10-20.
Chinese patent medicine of the present invention pharmaceutical methods is routinely made various dosage form, for example can be made into pill, capsule, tablet, powder, granule, unguentum, decoction etc.Certainly, can also make other suitable dosage forms, as long as but contain above-mentioned Chinese medicine ingredients, promptly should think to belong to the present invention.
Below in conjunction with the property of medicine pharmacology of various Chinese medicine ingredients, at length explain the present invention, wherein:
Radix Bupleuri: dispersing the stagnated live-QI to relieve the stagnation of QI, elimination stagnation of QI-blood.Be used to improve liver function, the calm detoxifcation of bringing down a fever.
The Radix Astragali: air making-up and spleen enlivening inducing diuresis to remove edema.Be used for deficiency of QI in middle-JIAO, a little less than the deficiency of spleen-YANG, fortuneization mistake department, retention of water-damp.
Carapax et Plastrum Testudinis: nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, the reinforcing the heart of nourishing blood.Be used for deficiency of YIN hectic fever hectic fever due to YIN-deficiency heat.
Carapax Trionycis: nourishing YIN for suppressing the hyperactive YANG, the hard masses softening and resolving painful abdominal mass that disappears.Be used for the liver-yin consume, the liver splenohepatomegaly.
Rhizoma Cyperi: depressed liver-energy dispersing and QI regulating resolving depression pain relieving.Be used for the abdominal distention feeling of fullness, pain in chest and hypochondrium, abdominal distention.
The Rhizoma Atractylodis Macrocephalae: QI invigorating spleen reinforcing, dampness diuretic.Be used to train the spleen reinforcing sun, invigorating spleen for diuresis, distension and fullness of the chest and abdomen.
Rhizoma Corydalis: blood-activating and qi-promoting pain relieving.Be used for coagulation of QI-blood, stasis of blood resistance is obstructed, breast side of body epigastric pain.
Pericarpium Citri Reticulatae Viride: soothing the liver dispelling the stagnated QI, long-pendingization of loosing stagnates.Be used for irritability stasis, the meridians painful abdominal mass is puckery, improves the costa sternales distention and fullness in the abdomen of stagnation of liver-QI due to stagnating.
Radix Angelicae Sinensis: QI invigorating regulating menstruation, promoting blood circulation and stopping pain.Be used for stagnation of QI-blood, blood stasis gathers, and has not only enriched blood but also can promoting the circulation of blood, has liver-protective pharmacological action.
Radix Aucklandiae (Radix Vladimiriae): promoting the circulation of QI to relieve pain.Be used for irritability stasis, discomfort uncomfortable in chest, stomach-QI being unable to descend normally, distension and fullness in the abdomen
Radix Paeoniae Rubra: clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.Be used for the QI and blood cohesion, functional activity of QI being not smooth, the logical internal organs of a surname are gathered around gas, and dispelling malignant blood removes crafty blood.
The Radix Paeoniae Alba: suppressing liver-YANG, the yin fluid astringing that nourishes blood, easing the affected liver to relieve pain.Be used for deficiency of liver-blood, deficiency of the yin of the liver, pain in the hepatic region, incoordination between the liver and spleen, hyperactive liver-QI attacking the stomach.
Rhizoma sparganic: removing blood stasis, promoting the circulation of QI to relieve pain.Be used for qi depression to blood stasis, mediation Liver Channel hematocele is eliminated and is gathered caking.
Rhizoma Curcumae: removing blood stasis, removing food stagnancy pain relieving.Be used for depression of liver-QI, the catharsis imbalance, coagulation of QI-blood is specially walked Liver Channel, and removing mass gathers stagnant blood.
Eupolyphaga Seu Steleophaga: removing blood stasis, be used for stagnation of QI-blood, the detumescence piece stimulates the menstrual flow and closes hepatosplenomegaly.
Fructus Schisandrae Chinensis: supplementing QI and nourishing YIN consolidates.The relieving restlessness of quenching the thirst, consumer edema regurgitation, transaminase lowering.
Cordyceps: have another name called Cordyceps.Invigorating the lung and the kidney, the hemostasisization disease.
Fructus Aurantii: regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.Be used for stagnation of circulation of vital energy about brestribs, distension pain.
Because the suitable cooperation of 18 kinds of above-mentioned Chinese medicine ingredients, thereby make Chinese patent medicine of the present invention play very outstanding effect aspect the treatment liver cirrhosis.
Compare with the various medicines that are used for the treatment of liver cirrhosis of prior art, the Chinese patent medicine of treatment liver cirrhosis of the present invention has following good effect: be applicable to the liver cirrhosis that is caused by the various causes of disease, the clinical treatment instant effect, effective and thorough, clinical symptoms is eliminated the back and is difficult for recurrence.And the full presciption medicine thing all is a formulary drug, and all medicines are all nontoxic, and therapeutic process has no adverse reaction and toxicity, side effect.It is a kind of special-purpose medicine that is used for the treatment of liver cirrhosis.
Enumerate embodiment below and application examples further specifies the present invention.
Embodiment 1: 18 above-mentioned flavor Chinese medicine ingredients are dried, press the meansigma methods of each weight ratio of constituents example scope in the above-mentioned prescription then, in every weight portion is that 10g takes by weighing medicine (gross weight is 5025g), these medicines are mixed together and are ground into fine powder, with the sieve of aperture 74 μ m (200 order), mixing, add suitable quantity of water, make the little pill of the about 3mm of particle diameter with pharmaceutical sector pellet processing machine commonly used, dry and promptly obtain the about 5000g of pill finished product of the present invention.This product is pale brown color to yellowish-brown, can melt by water, and abnormal smells from the patient is little, the little bitter band acid of mouthfeel.
Usage: every day 2-3 time, each 10-20g uses warm water delivery service.
For convenience's sake, when describing application examples and medical record example, pill of the present invention is called stilbene first pill for treating cirrhosis below.
Statistics application example (following case all is that each hospital's Medicine and Surgery is diagnosed as liver cirrhosis, and just changes inventor place department of Chinese medicine treatment over to by medical treatment is invalid):
The medical section at inventor place (Hua Xi hospital of Annex II institute of the Medical University Of Chongqing department of Chinese medicine) accepts various liver cirrhosis patient 100 examples for medical treatment altogether year May in February, 1993 to 1996.Wherein, male 83 examples, women 27 examples.Age-based statistics: 74 examples in 25-50 year; 26 examples in 50-73 year.Press severity of symptom statistics: hepatosplenomegaly, pain in the hepatic region, in a small amount of ascites companion abdominal distention, B ultrasonic is diagnosed as hepatic injury, blood examination abnormal liver function, 36 examples of early stage liver cirrhosis in belonging to; Except that above-mentioned symptom, also with jaundice, medium to a large amount of ascites, abdomen varicosis is spitted blood, and the stool blackout is obviously become thin, and belongs to 64 examples of middle and advanced stage liver cirrhosis.Add up by the liver cirrhosis induced factor: bring out 92 examples that cause by hepatitis B and other hepatitis; 2 examples of bringing out by alcoholism; Drug-induced 1 example; 5 examples of unknown cause.Use stilbene first pill for treating cirrhosis treatment of the present invention through inventor place medical treatment section, by obeying every day 3 times, each 10-20g (deciding on the state of an illness) takes.Treatment time is the shortest 3 months, and the longest 6 months, liver power recovery is normal.Ultrasound diagnosis: hepatosplenomegaly is little, and damage all recovers disappearances such as clinical symptoms and ascites substantially in the liver.
Medical record example 1:
Nie Zhangjin, man, 34 years old, its Long Jiu village, Nan'an District, Chongqing City.Suffer from hepatitis B in February, 93, because of pain in the hepatic region companion abdominal distention, whole skin obviously turns to be yellow, and is diagnosed as liver cirrhosis companion ascites to inventor place hospital internal medicine, and income internal medicine is in hospital, more than the 10 day conscious abdominal distention of being in hospital, and jaundice increases the weight of.I require Chinese traditional treatment, change the department of Chinese medicine treatment at inventor place immediately over to.Begin to take stilbene first pill for treating cirrhosis of the present invention immediately and the other treatment medicine of stopping using, subjective symptoms disappears after taking medicine 2 months, and 4 months blood examination liver functions of taking medicine are normal.Ultrasound diagnosis: hepatosplenomegaly is little, and the liver inner structure is normal substantially, no ascites.Drug withdrawal after continuing to take medicine 1 month.Follow up a case by regular visits to in March, 96 and do not recur.
Medical record example 2:
Zhou Xianming, woman, 51 years old, Nan Quan park, Chongqing City workman.October nineteen ninety-five, because of lumbago, yellowing of the skin, abdominal distention is diagnosed as through No.7 People's Hospital: calcareous cholecystitis, with obstructive jaundice.Income hospitalization 1 wheat harvesting period does not have and is clearly better, and changes the inventor place hospital November in the same year over to and through surgical diagnosis is: suppurative cholecystitis companion calculus, do the gallbladder removal operation.Find to be accompanied with liver cirrhosis companion ascites in the operation.Perform the operation and changed inventor place department of Chinese medicine treatment liver cirrhosis in back 15 days over to.The department of Chinese medicine is made decoction by the prescription of stilbene first pill for treating cirrhosis and is taken medicine to the patient, and the blood examination liver function is normal after taking medicine 2 months.All subjective symptomss disappear after taking medicine 5 months.Ultrasound diagnosis: the liver inner structure is clear substantially, no ascites.The drug withdrawal after 6 totally months of taking medicine.Follow up a case by regular visits to and do not have recurrence.
Medical record example 3:
Thank and gift man, 44 years old, big ferry, Chongqing City Ba Qiao people from village.In December, 94 is because of pain in the hepatic region, abdominal distention, and the whole body jaundice also increases the weight of day by day, is diagnosed as end-age cirrhosis through Chongqing City infectious hospital.Ultrasound diagnosis: hepatosplenomegaly, the liver inner structure is unclear, moderate ascites, abnormal liver function.Infectious hospital's hospitalization 20 days, the abdominal distention jaundice increased the weight of.Change hospital's department of Chinese medicine treatment at inventor place under the patient requires, take stilbene first pill for treating cirrhosis of the present invention transference cure after 3 months, the blood examination liver function is normal.After taking medicine 6 months, ultrasound diagnosis: hepatosplenomegaly is little, and the liver inner structure is normal substantially, and the patient requires drug withdrawal, follows up a case by regular visits to in May, 96 not recur.
Claims (8)
1, a kind of Chinese patent medicine that is used for the treatment of liver cirrhosis is characterized in that, it contains following traditional Chinese medicines composition (weight portion):
Radix Bupleuri 20-30, Radix Astragali 30-50, Carapax et Plastrum Testudinis 20-40,
Carapax Trionycis 20-40, Rhizoma Cyperi 20-30, Rhizoma Atractylodis Macrocephalae 30-60,
Rhizoma Corydalis 20-30, Pericarpium Citri Reticulatae Viride 20-30, Radix Angelicae Sinensis 20-30,
Radix Aucklandiae (Radix Vladimiriae) 20-30, Radix Paeoniae Rubra 30-60, Radix Paeoniae Alba 20-30,
Rhizoma sparganic 20-30, Rhizoma Curcumae 20-30, Eupolyphaga Seu Steleophaga 20-30,
Fructus Schisandrae Chinensis 30-50, Cordyceps 5-10, Fructus Aurantii 10-20.
2, the Chinese patent medicine that is used for the treatment of liver cirrhosis as claimed in claim 1 is characterized in that, its dosage form is a pill.
3, the Chinese patent medicine that is used for the treatment of liver cirrhosis as claimed in claim 1 is characterized in that, its dosage form is a capsule.
4, the Chinese patent medicine that is used for the treatment of liver cirrhosis as claimed in claim 1 is characterized in that, its dosage form is a tablet.
5, the Chinese patent medicine that is used for the treatment of liver cirrhosis as claimed in claim 1 is characterized in that, its dosage form is a powder.
6, the Chinese patent medicine that is used for the treatment of liver cirrhosis as claimed in claim 1 is characterized in that, its dosage form is a granule.
7, the Chinese patent medicine that is used for the treatment of liver cirrhosis as claimed in claim 1 is characterized in that, its dosage form is a unguentum.
8, the Chinese patent medicine that is used for the treatment of liver cirrhosis as claimed in claim 1 is characterized in that, its dosage form is a decoction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96109557A CN1053832C (en) | 1996-08-29 | 1996-08-29 | Chinese patent drug for cirrhosis of liver |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96109557A CN1053832C (en) | 1996-08-29 | 1996-08-29 | Chinese patent drug for cirrhosis of liver |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1147398A true CN1147398A (en) | 1997-04-16 |
| CN1053832C CN1053832C (en) | 2000-06-28 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96109557A Expired - Fee Related CN1053832C (en) | 1996-08-29 | 1996-08-29 | Chinese patent drug for cirrhosis of liver |
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| Country | Link |
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| CN (1) | CN1053832C (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101015671B (en) * | 2007-02-02 | 2010-04-21 | 姚传美 | Chinese patent drug for treating cirrhosis |
| CN101869686B (en) * | 2009-11-05 | 2011-08-31 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating cirrhosis |
| CN101530594B (en) * | 2009-04-17 | 2012-08-15 | 谷井文 | Ultra-fine grain traditional Chinese medicine defibrination paste used for treating liver cirrhosis |
| WO2016183703A1 (en) * | 2015-05-18 | 2016-11-24 | 邓鑫 | Composition for treating portal hypertension of cirrhosis, and preparation method therefor |
| CN107496736A (en) * | 2017-08-28 | 2017-12-22 | 段祖垒 | A kind of Chinese medicine powder and preparation method for treating damp-heat type chronic hepatitis B |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1096681A (en) * | 1993-06-22 | 1994-12-28 | 张俊才 | Hepatosis treating medicine powder |
| CN1052157C (en) * | 1993-06-30 | 2000-05-10 | 付军廷 | Softing liver and contracting spleen tablet |
| CN1045890C (en) * | 1993-08-14 | 1999-10-27 | 焦柏忠 | Hepatitis capsule and its prepn. technique |
-
1996
- 1996-08-29 CN CN96109557A patent/CN1053832C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101015671B (en) * | 2007-02-02 | 2010-04-21 | 姚传美 | Chinese patent drug for treating cirrhosis |
| CN101530594B (en) * | 2009-04-17 | 2012-08-15 | 谷井文 | Ultra-fine grain traditional Chinese medicine defibrination paste used for treating liver cirrhosis |
| CN101869686B (en) * | 2009-11-05 | 2011-08-31 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating cirrhosis |
| WO2016183703A1 (en) * | 2015-05-18 | 2016-11-24 | 邓鑫 | Composition for treating portal hypertension of cirrhosis, and preparation method therefor |
| CN107496736A (en) * | 2017-08-28 | 2017-12-22 | 段祖垒 | A kind of Chinese medicine powder and preparation method for treating damp-heat type chronic hepatitis B |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1053832C (en) | 2000-06-28 |
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