CN114732713A - A multi-electrode acupoint detection design method based on bioelectrical impedance - Google Patents

Abstract

The invention relates to a multi-electrode acupoint detection design method based on bioelectrical impedance, which is based on the acupoint distribution characteristics on the classical meridian theory and designs a multi-electrode array scheme. And determining the size and the spacing of the electrodes according to the electrical measurement evaluation function, and arranging and forming the acupoint detection electrode array according to a distributed method. An acupuncture point detection system is designed, an excitation signal is injected into the skin from an excitation electrode according to the technical characteristics of the bioelectrical impedance, a multi-electrode array collects bioelectrical signals of corresponding skin areas, and the positions of acupuncture point positions are obtained through calculation and analysis. The invention can reduce the measurement error caused by using a single electrode to detect the acupuncture point, and greatly improve the accuracy of acupuncture point detection.

Description

A multi-electrode acupoint detection design method based on bioelectrical impedance

(1) Technical field

The invention relates to a multi-electrode acupoint detection design method based on bioelectrical impedance, which can be used for real-time measurement of human skin acupoints, and belongs to the technical field of bioelectrical impedance.

(2) Background technology

Bioelectrical impedance (electrical bio-impedance) technology is a non-invasive detection technology that uses the electrical characteristics and changes of biological tissues and organs to extract biomedical information related to human physiology and pathological conditions. The electrodes of the watch send a tiny measurement current or voltage to the test object, detect the corresponding electrical impedance and its changes, and then obtain relevant physiological and pathological information according to different application purposes. The technology is non-invasive, cheap, safe, non-toxic and harmless, simple to operate, and rich in information, which is easy for doctors and patients to accept.

Acupoints, scientifically called acupoints, refer to the special points on the skin surface of the human body, that is, the characteristic points on the skin surface. Most of the acupuncture points are located on the meridian lines. Chinese medicine can treat diseases by stimulating the corresponding meridian points through acupuncture or massage, tap, and moxa. Acupoints are unique terms in Chinese culture and traditional Chinese medicine, and they are mostly places with many nerve endings and blood vessels.

How to make the diagnostic indicators of TCM more objective and have diagnostic reference value is a breakthrough for the development of modern TCM.

According to research, the bioelectrical impedance of acupoints is lower than that of non-acupoints. When the human body has a disease, the bioelectrical impedance of the corresponding acupoints will change. Therefore, by monitoring the changing trend of the bioelectrical impedance of the acupoints, the health of the human body can be easily and intuitively grasped. At present, there are few effective methods for detecting acupoints. The commonly used method is mainly to use a single electrode to detect acupuncture points, and it is impossible to guarantee that the detection of each measurement point is realized under the same conditions, which is easy to play a role in the measurement results. Large interference, resulting in a large deviation of the acupoint detection position.

(3) Contents of the invention

The purpose of the present invention is to provide a multi-electrode acupoint detection design method based on bioelectrical impedance, which can satisfy that each measurement point has the same condition, thereby improving the accuracy of detecting acupoint positions.

In order to achieve the above purpose, the present invention provides a multi-electrode acupoint detection design method based on bioelectrical impedance, which is based on the distribution characteristics of acupoints on the classical meridian theory, and designs a multi-electrode array scheme. According to the electric measurement evaluation function, the size and spacing of the electrodes are determined, and the acupoint detection electrode arrays are arranged according to the distributed method. The acupoint detection system is designed, and the excitation signal is injected into the skin from the excitation electrode according to the characteristics of bioelectrical impedance technology. The multi-electrode array collects the bioelectrical signal from the corresponding skin area, and the position of the acupuncture point is obtained through calculation and analysis.

Further, the probes in the multi-electrode array and the needle sheath with conductive properties are formed as detection electrodes.

Further, according to the electric measurement evaluation function, the size and spacing of the electrodes are determined, and the acupoint detection electrode arrays are arranged according to the distributed method.

检测电极在待测皮肤区域点上的函数峰值UF_max，并计算出对应的点面积B_xB_y；wherein, according to the electrical measurement evaluation function

Detect the function peak value UF _max of the electrode on the point of the skin area to be tested, and calculate the corresponding point area B _{x By} ;

Among them, based on the comparison and analysis of the electrical measurement evaluation function σ value and the physical characteristics of the acupoint diameter of 3-5mm, it is determined that the contact size of the electrode is in the range of 2-5mm, the length of the electrode is in the range of 14-26mm, and the distance between the electrodes is in the range of 2 mm. -4mm, and arranged according to the distributed method to form the acupoint detection electrode array.

The design method of the multi-electrode acupoint detection is as follows:

Step 1. According to the technical characteristics of bioelectrical impedance, place the positive and negative ends of the medical electrode as the excitation electrode at both ends of the acupoint area to be tested, and ensure that there is a certain space between the positive and negative ends of the excitation electrode to place the acupoint detection electrode array. The positive end of the electrical signal detection and the negative end of the electrical signal detection composed of the medical electrodes are formed. At the same time, the negative end of the electrical signal detection is placed far away from the area of the acupuncture point to be tested, and is close to the negative end of the excitation electrode, and the interval range is 2-4cm;

Step 2, placing the acupoint detection electrode array in the acupoint area to be tested, and controlling the equidistant collection of bioelectric signals in time by each detection electrode in the acupoint detection electrode array through the multi-electrode array control device on the acupoint detection system;

Step 3: After the acupoint detection system performs signal processing on the bioelectrical signals collected by each detection electrode, the corresponding bioelectrical impedance is calculated and stored in the microcontroller for the bioelectrical signals collected by each detection point. In contrast to the differences in the bioelectrical impedance of non-acupoint points, the system selects the detection points whose electrical impedance values are significantly lower than those of other electrical impedance values as the corresponding acupoint detection positions.

Further, the acupoint detection system includes:

The acupoint detection system is composed of a voltage-controlled current source device, a microcontroller, a multi-electrode array, a multi-electrode array control device, a signal conditioning device, a signal reading device and a power supply device;

Wherein, the voltage-controlled current source device converts the fixed-frequency sinusoidal voltage signal generated by the microcontroller into a current signal, and injects it into the skin through the positive end of the excitation electrode as an excitation signal;

Wherein, the excitation signal flows out of the skin through the negative end of the excitation electrode and then passes through the sampling resistor as the reference input signal, and the multi-electrode array time-divisions collects the electrical signals of each detection point in the skin area to be measured as the measurement input signal;

Wherein, the measurement input signal is sequentially processed by the multi-electrode array control device, the signal conditioning device and the signal reading device to obtain the voltage signal of each detection point;

Wherein, after the microcontroller collects the reference input signal and the voltage signal of each point at the same time, the bioelectrical impedance value of each detection point is calculated and saved. The analysis gives the exact location of the acupoint detection point.

The invention provides a multi-electrode acupoint detection design method based on bioelectrical impedance, and designs a multi-electrode array scheme based on the distribution characteristics of acupoints on the classical meridian theory. According to the electric measurement evaluation function, the size and spacing of the electrodes are determined, and the acupoint detection electrode arrays are arranged according to the distributed method. The acupoint detection system is designed, and the excitation signal is injected into the skin from the excitation electrode according to the characteristics of bioelectrical impedance technology. The multi-electrode array collects the bioelectrical signal from the corresponding skin area, and the position of the acupuncture point is obtained through calculation and analysis. The invention can reduce the measurement error caused by using a single electrode to detect acupoint points, and greatly improve the accuracy of acupoint detection.

(4) Description of drawings

In order to explain the embodiments of the present invention or the technical solutions in the prior art more clearly, the following briefly introduces the accompanying drawings that need to be used in the description of the embodiments or the prior art. Obviously, the accompanying drawings in the following description are only These are some embodiments of the present invention. For those of ordinary skill in the art, other drawings can also be obtained according to these drawings without creative efforts.

FIG. 1 is a schematic diagram of steps of a method for designing multi-electrode acupoint detection based on bioelectrical impedance provided by the present invention.

FIG. 2 is a schematic structural diagram of a multi-electrode array provided by the present invention.

FIG. 3 is a schematic structural diagram of a bioelectrical impedance-based multi-electrode acupoint detection system provided by the present invention.

FIG. 4 is an actual data measurement diagram of the bioelectrical impedance-based multi-electrode acupoint detection system provided by the present invention.

FIG. 5 is a schematic diagram of acupoint measurement of the bioelectrical impedance-based multi-electrode acupoint detection system provided by the present invention.

FIG. 6 is a measurement diagram of skin acupoints of the bioelectrical impedance-based multi-electrode acupoint detection system provided by the present invention.

(5) Specific implementation manner

The following describes in detail the embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein the same or similar reference numerals refer to the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary, and are intended to explain the present invention and should not be construed as limiting the present invention.

In the description of the present invention, it should be understood that the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", The orientations or positional relationships indicated by "horizontal", "top", "bottom", "inside", "outside", etc. are based on the orientations or positional relationships shown in the accompanying drawings, which are only for the convenience of describing the present invention and simplifying the description, rather than Indication or implication that the referred device or element must have a particular orientation, be constructed and operate in a particular orientation, is not to be construed as a limitation of the invention. In addition, in the description of the present invention, "plurality" means two or more, unless otherwise expressly and specifically defined.

Referring to FIG. 1, the present invention provides a multi-electrode acupoint detection design method based on bioelectrical impedance, including the following steps:

S101. Design a multi-electrode array scheme based on the distribution characteristics of acupoints on the classical meridian theory.

The probe and the needle sheath are fixed by solder.

S102 , determining the size and spacing of electrodes according to the evaluation function of electrical measurement, and arranging them according to a distributed method to form a point detection electrode array, as shown in FIG. 2 .

检测电极在待测皮肤区域点上的函数峰值UF_max，并计算出对应的点面积B_xB_y。wherein, according to the electrical measurement evaluation function

The function peak value UF _max of the electrode on the point of the skin area to be tested is detected, and the corresponding point area B _x By is _calculated .

Among them, based on the comparison and analysis of the electrical measurement evaluation function σ value and the physical characteristics of the acupoint diameter of 3-5mm, it is determined that the contact size of the electrode is in the range of 2-5mm, the length of the electrode is in the range of 14-26mm, and the distance between the electrodes is in the range of 2 mm. -4mm, and arranged according to the distributed method to form the acupoint detection electrode array.

Among them, the multi-electrode acupoint detection design method is as follows:

Step 1. According to the technical characteristics of bioelectrical impedance, place the positive and negative ends of the medical electrode as the excitation electrode at both ends of the acupoint area to be tested, and ensure that there is a certain space between the positive and negative ends of the excitation electrode to place the acupoint detection electrode array. It consists of the positive end of the electrical signal measurement and the negative end of the electrical signal measurement composed of the medical electrodes. At the same time, the negative end of the electrical signal measurement is placed away from the area of the acupuncture point to be measured, and is close to the negative end of the excitation electrode, and the interval range is 2-4cm. The way is shown in Figure 6;

Step 2, placing the acupoint detection electrode array in the acupoint area to be tested, and controlling the equidistant collection of bioelectric signals in time by each detection electrode in the acupoint detection electrode array through the multi-electrode array control device on the acupoint detection system;

Step 3: After the acupoint detection system performs signal processing on the bioelectrical signals collected by each detection electrode, the corresponding bioelectrical impedance is calculated and stored in the microcontroller for the bioelectrical signals collected by each detection point. In contrast to the differences in the bioelectrical impedance of non-acupoint points, the system selects the detection points whose electrical impedance values are significantly lower than those of other electrical impedance values as the corresponding acupoint detection positions.

S103 , designing an acupoint detection system, injecting an excitation signal from an excitation electrode into the skin according to the technical characteristics of bioelectrical impedance, and the acupoint detection electrode array collects bioelectrical signals from the corresponding skin area, and obtains the acupoint position through calculation and analysis, as shown in FIG. 6 .

The acupoint detection system, as shown in Figure 3, consists of a voltage-controlled current source device, a microcontroller, a multi-electrode array, a multi-electrode array control device, a signal conditioning device, a signal reading device, and a power supply device.

The voltage-controlled current source device converts the fixed frequency and fixed amplitude sinusoidal voltage signal generated by the microcontroller into a current signal, and injects it into the skin through the positive terminal of the excitation electrode.

Wherein, the voltage-controlled current source device is used to increase the impedance of the output end and improve the load capacity by adding a voltage follower to the positive and negative feedback loop of the forward amplifier circuit.

The excitation signal flows out of the skin through the negative end of the excitation electrode and then passes through the sampling resistor as the reference input signal, and the electrical signals of each measurement point in the skin area to be measured are collected through the acupoint detection electrode array as the measurement input signal.

The multi-electrode array control device designs equidistant collection times for each detection electrode in the acupoint detection electrode array according to the sampling frequency of the ADC chip at the back end of the circuit, so as to ensure the consistency of the collection time of each electrode.

Among them, in order to ensure the uniformity of the collection of each detection channel in the acupoint detection electrode array at equal intervals, the multi-electrode array control device designs a buffer circuit composed of a voltage follower at the front end of the multi-electrode array control device to reduce the multi-electrode The array control device generates crosstalk between signals due to gating different detection electrodes, and at the same time increases the input impedance of the circuit measurement front end.

The signal conditioning device mainly performs differential amplification of the human skin surface signal obtained by the acupoint detection electrode array by designing a differential amplifying circuit as the core, and simultaneously converts it into a single-channel human skin surface signal;

Among them, the single-channel human skin surface signal will contain some noise in the environment, especially the noise such as static electricity in the human skin. Therefore, the signal conditioning device is also designed to filter the noise of the single-channel human skin surface signal. Therefore, the filtered single-channel human skin surface signal is used as a single-channel measurement input signal.

The signal reading device obtains the amplitude ratio signal for the incoming single-channel measurement input signal and the reference input signal through the amplitude and phase detection circuit. The present invention obtains the amplitude ratio signal through the circuit of FIG. 5 . The amplitude ratio signal V _MAG is shown in formula (1):

V _MAG =V _SLP *log(V _INA /V _INB ) (1)

Wherein, U _INA and V _INB respectively represent the amplitudes of the measurement input signal and the reference input signal, and V _SLP is the output slope.

When the amplitude ratio signal V _MAG of each detection point is obtained, the present invention adopts the method of connecting the reference resistor R2 and the sampling limb R1 in series, as shown in FIG. 5 , using the voltage division principle of the series circuit to calculate the impedance of each detection point, sampling The calculation formula of limb R1 is shown in formula (2):

As shown in Figure 4, when the electrical impedance of a certain detection point is significantly lower than that of other detection points, according to the low impedance characteristic of the acupuncture point, the system gives the position of the acupuncture point corresponding to the detection electrode in the acupoint detection electrode array.

The invention provides a multi-electrode acupoint detection design method based on bioelectrical impedance, and designs a multi-electrode array scheme based on the distribution characteristics of acupoints on the classical meridian theory. According to the electric measurement evaluation function, the size and spacing of the electrodes are determined, and the acupoint detection electrode arrays are arranged according to the distributed method. The acupoint detection system is designed, and the excitation signal is injected into the skin from the excitation electrode according to the characteristics of bioelectrical impedance technology. The multi-electrode array collects the bioelectrical signal from the corresponding skin area, and the position of the acupuncture point is obtained through calculation and analysis. The invention can reduce the measurement error caused by using a single electrode to detect acupoint points, and greatly improve the accuracy of acupoint detection.

The above disclosure is only a preferred embodiment of the present invention, and of course, it cannot limit the scope of rights of the present invention. Those of ordinary skill in the art can understand that all or part of the process for realizing the above-mentioned embodiment can be realized according to the rights of the present invention. The equivalent changes required to be made still belong to the scope covered by the invention.

Claims (5)

1. A multi-electrode acupoint detection design method based on bioelectrical impedance. The method is characterized in that: based on the acupoint distribution characteristics on the classical meridian theory, a multi-electrode array scheme is designed.

And determining the size and the spacing of the electrodes according to the electrical measurement evaluation function, and arranging and forming the acupoint detection electrode array according to a distributed method.

An acupuncture point detection system is designed, an excitation signal is injected into the skin from an excitation electrode according to the technical characteristics of the bioelectrical impedance, a multi-electrode array collects bioelectrical signals of corresponding skin areas, and the positions of acupuncture point positions are obtained through calculation and analysis.

2. The bioelectrical impedance-based multi-electrode acupoint detection design method according to claim 1, wherein a multi-electrode array scheme is designed based on acupoint distribution characteristics on the classical meridian theory, and comprises:

the probes in the multi-electrode array and the needle sheath with conductive property form a detection electrode.

3. The bioelectrical impedance-based multi-electrode acupoint detection design method according to claim 1, wherein the sizes and the intervals of the electrodes are determined according to an electrical measurement evaluation function, and the acupoint detection electrode arrays are arranged and formed according to a distributed method, and the method comprises the following steps:

evaluating a function from an electrical measurement

Function peak UF of detecting electrode on skin area point to be detected_maxAnd calculating the corresponding dot area B_xB_yAnd comparing and analyzing the sigma value of the electrical measurement evaluation function and the physical characteristics of the acupuncture point with the diameter of 3-5mm, determining that the contact size range of the electrode is 2-5mm, the electrode length range is 14-26mm, and the electrode spacing range is 2-4mm, and arranging according to a distributed method to form the acupuncture point detection electrode array.

4. The bioelectrical impedance-based multi-electrode acupoint detection design method of claim 1. The method is characterized in that:

placing positive and negative ends of a medical electrode serving as an excitation electrode at two ends of an acupoint region to be detected according to the technical characteristics of bioelectrical impedance, and ensuring that a certain space can be reserved between the positive end and the negative end of the excitation electrode to place an electric signal detection positive end consisting of an acupoint detection electrode array and an electric signal detection negative end consisting of the medical electrode, wherein the electric signal detection negative end is placed at a position far away from the acupoint region to be detected and close to the negative end of the excitation electrode, and the spacing range is 2-4 cm;

secondly, placing the acupoint detection electrode array in the acupoint area to be detected, and controlling each detection electrode in the acupoint detection electrode array to acquire bioelectricity signals at equal intervals in time through a multi-electrode array control device on the acupoint detection system;

and step three, after the bioelectrical signals acquired by the detection electrodes are subjected to signal processing by the acupoint detection system, respectively calculating and storing corresponding bioelectrical impedances of the bioelectrical signals acquired by the detection points in the microcontroller, and selecting the detection points corresponding to the bioelectrical impedances which are obviously lower than other impedance values in all the bioelectrical impedance values as corresponding acupoint detection positions by the system according to the bioelectrical impedance difference characteristics of the acupoint points and non-acupoint points.

5. The bioelectrical impedance-based multi-electrode acupoint detection design method of claim 1, wherein the acupoint detection system is designed to inject an excitation signal from an excitation electrode into the skin according to the technical characteristics of bioelectrical impedance, the multi-electrode array collects bioelectrical signals from corresponding skin areas, and the positions of the acupoint positions are obtained through calculation and analysis, and the method comprises:

the acupoint detection system is composed of a voltage-controlled current source device, a microcontroller, a multi-electrode array control device, a signal conditioning device, a signal reading device and a power supply device. Converting a fixed-frequency sinusoidal voltage signal generated by a microcontroller into a current signal by using a voltage-controlled current source device, and injecting the current signal into the skin through the positive end of an excitation electrode; the excitation signal flows out of the skin through the negative end of the excitation electrode and then is used as a reference input signal through the sampling resistor, and the electric signals of all detection points in the skin area to be detected are collected in a time-sharing mode through the multi-electrode array to be used as a measurement input signal; processing the measurement input signal by a multi-electrode array control device, a signal conditioning device and a signal reading device in sequence to obtain a voltage signal of each detection point; after the microcontroller collects the reference input signal and the voltage signal of each point at the same time, the bioelectrical impedance of each point is calculated and stored, and the accurate position of the acupoint detection point is systematically analyzed and given according to the difference characteristics of the bioelectrical impedance of the acupoint and the non-acupoint.

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