CN114715829A - Sterile high-capacity liquid subpackaging consumable - Google Patents
Sterile high-capacity liquid subpackaging consumable Download PDFInfo
- Publication number
- CN114715829A CN114715829A CN202210279921.0A CN202210279921A CN114715829A CN 114715829 A CN114715829 A CN 114715829A CN 202210279921 A CN202210279921 A CN 202210279921A CN 114715829 A CN114715829 A CN 114715829A
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- Prior art keywords
- liquid
- bag
- pipeline
- pinch valve
- way
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- 239000007788 liquid Substances 0.000 title claims abstract description 158
- 238000003860 storage Methods 0.000 claims abstract description 22
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 21
- 239000000463 material Substances 0.000 claims abstract description 19
- 239000011550 stock solution Substances 0.000 claims description 19
- 239000012452 mother liquor Substances 0.000 claims description 14
- 239000003814 drug Substances 0.000 claims description 11
- 230000003044 adaptive effect Effects 0.000 claims description 5
- 230000007246 mechanism Effects 0.000 claims description 4
- 238000000034 method Methods 0.000 abstract description 8
- 230000008569 process Effects 0.000 abstract description 8
- 238000012360 testing method Methods 0.000 abstract description 5
- 238000004519 manufacturing process Methods 0.000 description 6
- 239000000047 product Substances 0.000 description 5
- 238000004806 packaging method and process Methods 0.000 description 4
- 239000002775 capsule Substances 0.000 description 3
- 230000003749 cleanliness Effects 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 239000012467 final product Substances 0.000 description 3
- 239000012535 impurity Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000010926 purge Methods 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
- B67C—CLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
- B67C3/00—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus; Filling casks or barrels with liquids or semiliquids
- B67C3/007—Applications of control, warning or safety devices in filling machinery
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
- B67C—CLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
- B67C3/00—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus; Filling casks or barrels with liquids or semiliquids
- B67C3/02—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus
- B67C3/16—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus using suction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
- B67C—CLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
- B67C3/00—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus; Filling casks or barrels with liquids or semiliquids
- B67C3/02—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus
- B67C3/22—Details
- B67C3/222—Head-space air removing devices, e.g. by inducing foam
Landscapes
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The invention relates to the technical field of liquid split charging, in particular to an aseptic high-capacity liquid split charging consumable, which comprises a mother liquid bag, wherein a liquid pipeline is arranged on the mother liquid bag, a peristaltic pump is arranged on the liquid pipeline, a liquid pressure gauge is arranged on the liquid pipeline and on the left side of the peristaltic pump, a bag-type filter is arranged on the liquid pipeline and on the left side of the liquid pressure gauge, an air filter is arranged at the tail end of the liquid pipeline, an aseptic quick plug is arranged at the left end of a liquid branch pipe, and the outer ends of a cross four-way joint and a T-shaped three-way joint are both connected with liquid storage bottles; the stability is high, the safety of a liquid path is controlled through a pressure feedback program, and leakage is prevented; the safety is high, and the gas pressure maintaining test can be used for checking the integrity of consumable materials before the consumable materials are used formally; compared with manual operation, the product loss caused by misoperation and process loss can be further reduced.
Description
Technical Field
The invention relates to the technical field of liquid subpackage, in particular to an aseptic high-capacity liquid subpackage consumable material.
Background
In the production process of biological medicines, large-capacity subpackaging is generally required and the sterility in the whole process is required to be ensured. At present, in the process of one-line production and packaging, manual subpackaging operation modes are generally used in large quantity, the personnel cost is high, and the operation efficiency is low. In addition, the stability, safety and traceability of manual operations are difficult to guarantee. This scheme aims at designing a section and can be used for the aseptic partial shipment consumptive material of automatic partial shipment equipment, through the full automation mechanized operation of cooperation automation equipment in order to realize biological medicine partial shipment. Meanwhile, the mounting mode is simplified, the production cost is optimized, and the precision and the stability in the split charging process are obviously improved.
Disclosure of Invention
The invention aims to provide a sterile high-capacity liquid subpackaging consumable to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
the utility model provides an aseptic large capacity liquid partial shipment consumptive material, includes the mother liquor bag, be provided with the liquid pipeline on the mother liquor bag, be provided with the peristaltic pump on the liquid pipeline, the liquid pipeline is provided with the liquid pressure gauge on the left side that lies in the peristaltic pump, the liquid pipeline is last and be located the left side of liquid pressure gauge and be provided with bag formula filter, the liquid pipeline is on and be located bag formula filter's rear side front and back symmetry and be provided with first pinch valve, the tail end of liquid pipeline is provided with air cleaner, the liquid pipeline is on and be located and be provided with the liquid branch pipe between the first pinch valve, be provided with the gas-liquid pressure gauge on the liquid branch pipe, the left end of liquid branch pipe is provided with aseptic fast plug, main liquid route is installed in the left side of aseptic fast plug, evenly be provided with cross four way joint on the main liquid pipeline, the tail end of main liquid route is provided with T type three way connection, the outer ends of the cross-shaped four-way joint and the T-shaped three-way joint are both connected with liquid storage bottles, and the cross-shaped four-way joint and the T-shaped three-way joint are both provided with second pinch valves.
As a preferable scheme of the invention, the mother liquid bag, the liquid pipeline, the liquid pressure gauge, the bag type filter, the air filter, the liquid branch pipe, the gas-liquid pressure gauge, the sterile quick plug, the main liquid pipeline, the cross four-way joint, the T-shaped three-way joint and the liquid storage bottle are all disposable consumables.
As a preferable scheme of the invention, the bottle cap of the liquid storage bottle is also provided with an air filter.
As the preferred scheme of the invention, the liquid storage bottle consumables can be designed into 6 groups, or 2 groups or 4 groups, each group of liquid storage bottles and the main liquid path are provided with disposable quick-connection connectors for quick connection with other groups of liquid storage bottles, and the connection can be carried out in a C-level environment.
As a preferable scheme of the invention, the mother liquor bag stores the stock solution of the semi-finished biological medicines and can support the split charging of mother liquor with the volume of 10L-1000 mL.
In a preferred embodiment of the present invention, the capsule filter is of a microporous design.
According to the preferred scheme of the invention, the peristaltic pump, the first pinch valve and the second pinch valve are matched with an operating mechanism for the adapting device.
According to a preferable scheme of the invention, a pinch valve clamping position is arranged on the liquid pipeline in a manner of being matched with the first pinch valve, and pinch valve clamping positions are arranged on the cross four-way joint and the T-shaped three-way joint in a manner of being matched with the second pinch valve.
Compared with the prior art, the invention has the beneficial effects that:
1. according to the invention, the split charging consumable material has high efficiency, and the disposable sterile quick plug can simplify the difficulty of operation; the stability is high, the safety of a liquid path is controlled through a pressure feedback program, and leakage is prevented; the safety is high, and the gas pressure maintaining test can be used for checking the integrity of the consumable materials before the consumable materials are used formally; compared with manual operation, the product loss caused by misoperation and process loss can be further reduced.
2. In the invention, the air filter 6 is used for filtering the air entering the consumable, so that the product loss is effectively reduced; the mother liquid bag 1 is used for storing the stock solution of the semi-finished biological medicine, the mother liquid with the volume of 10L-1000 mL can be subpackaged, and the peristaltic pump 2 works and opens a corresponding pinch valve to realize the automatic subpackaging function of the biological medicine; the bag type filter 4 adopts a micropore design, so that most of impurities generated in the production process in the stock solution can be filtered, and the cleanliness of the final product during subpackaging is ensured to meet the standard;
drawings
FIG. 1 is a structural view of a large capacity liquid dispensing consumable of the present invention;
FIG. 2 is a schematic view of a fluid path structure according to the present invention;
FIG. 3 is a schematic view of the fluid path of the present invention.
In the figure: 1. a mother liquor bag; 101. a liquid line; 102. a liquid branch pipe; 2. a peristaltic pump; 3. a liquid pressure gauge; 4. a bladder filter; 5. a first pinch valve; 6. an air filter; 7. a gas-liquid pressure gauge; 8. sterile quick plugs; 9. a main liquid path; 10. a cross four-way joint; 11. a T-shaped three-way joint; 12. a liquid storage bottle; 13. a second pinch valve.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and all other embodiments obtained by a person of ordinary skill in the art without creative efforts based on the embodiments of the present invention belong to the protection scope of the present invention.
In order to facilitate an understanding of the invention, the invention will now be described more fully hereinafter with reference to the accompanying drawings, in which several embodiments of the invention are shown, but which can be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like are used herein for purposes of illustration only.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
Example (b): please refer to fig. 1-3, which shows a sterile high-capacity liquid dispensing consumable, comprising a mother liquid bag 1, a liquid pipeline 101 is arranged on the mother liquid bag 1, a peristaltic pump 2 is arranged on the liquid pipeline 101, a liquid pressure gauge 3 is arranged on the liquid pipeline 101 and on the left side of the peristaltic pump 2, a bag filter 4 is arranged on the liquid pipeline 101 and on the left side of the liquid pressure gauge 3, first pinch valves 5 are symmetrically arranged on the liquid pipeline 101 and on the back and forth of the back side of the bag filter 4, an air filter 6 is arranged at the tail end of the liquid pipeline 101, a liquid branch pipe 102 is arranged on the liquid pipeline 101 and between the first pinch valves 5, a gas-liquid pressure gauge 7 is arranged on the liquid branch pipe 102, a sterile quick plug 8 is arranged at the left end of the liquid branch pipe 102, a main liquid passage 9 is arranged on the left side of the sterile quick plug 8, cross four-way joints 10 are uniformly arranged on the main liquid passage 9, the tail end of the main liquid path 9 is provided with a T-shaped three-way joint 11, the outer ends of the cross four-way joint 10 and the T-shaped three-way joint 11 are both connected with a liquid storage bottle 12, and the cross four-way joint 10 and the T-shaped three-way joint 11 are both provided with a second pinch valve 13; the stability is high, the safety of a liquid path is controlled through a pressure feedback program, and leakage is prevented; the safety is high, and the gas pressure maintaining test can be used for checking the integrity of the consumable materials before the consumable materials are used formally; compared with manual operation, the product loss caused by misoperation and process loss can be further reduced.
In this embodiment, mother liquor bag 1, liquid pipeline 101, liquid pressure gauge 3, bag filter 4, air cleaner 6, liquid branch 102, gas-liquid pressure gauge 7, aseptic quick plug 8, main liquid way 9, cross four way connection 10, T type three way connection 11 and stock solution bottle 12 are disposable consumptive material, are provided with air cleaner 6 on the 12 bottle lids of stock solution bottle equally, are used for filtering the inside air of entering consumptive material through air cleaner 6, effectual reduction product loss.
In this embodiment, stock solution bottle 12 consumptive material can design for 6 a set of, 2 a set of or 4 a set of also, every stock solution bottle 12 of group and main liquid way 9 are furnished with disposable quick connector, be used for with other stock solution bottle 12 high-speed joint of group, it can go on in C level environment to connect, deposit biological medicine semi-manufactured goods stoste in mother liquor bag 1, can support voluminous 10L ~ 1000mL mother liquor partial shipment, deposit biological medicine semi-manufactured goods stoste in through mother liquor bag 1, can support voluminous 10L ~ 1000mL mother liquor partial shipment, work and open corresponding pinch valve through peristaltic pump 2, realize the automatic partial shipment function of biological medicine.
In this embodiment, the capsule filter 4 adopts the micropore design, and through the capsule filter 4 adopting the micropore design, can filter the impurity that produces in most production processes in the stoste, the cleanliness factor of final product accords with the standard when guaranteeing the partial shipment.
In the embodiment, the peristaltic pump 2, the first pinch valve 5 and the second pinch valve 13 are adaptive devices and are configured with working mechanisms, a pinch valve clamping position is arranged on the liquid pipeline 101 in an adaptive mode with the first pinch valve 5, a pinch valve clamping position is arranged on the cross four-way joint 10 and the T-shaped three-way joint 11 in an adaptive mode with the second pinch valve 13, and the pinch valve clamping position is used for being clamped into a pinch valve to control the on-off position of a liquid path.
The working principle is as follows: when the device is used, a gas source is connected with a purging gas inlet, the first pinch valve 5 at the rear side is opened, and other pinch valves are closed; introducing air to a specific pressure; closing the pinch valve 1; maintaining the pressure for a specific time; opening all the second pinch valves 12 to discharge the pressure of the main liquid circuit 9; opening the front first pinch valve 5; opening the second pinch valve 15 (either fully open, or open a designated pinch valve); the peristaltic pump 2 works, mother liquor flows into the liquid storage bottle 12 which correspondingly opens the pinch valve; after the liquid amount of the corresponding liquid storage bottle 12 reaches a set value, the corresponding pinch valve is closed; after the liquid amount of all the liquid storage bottles 12 reaches a set value, the peristaltic pump 2 is stopped, and all the pinch valves are closed; opening a given one of the second pinch valves 13; opening the rear first pinch valve 5; air is introduced to blow the liquid in the main liquid path 9 into the designated liquid storage bottle 12; closing all pinch valves; connecting pipelines of the liquid storage bottles 12 to perform sterile hot melting to complete split charging;
FIG. three shows the combination of the consumables and the corresponding devices of the large-capacity liquid split charging unit, wherein the peristaltic pump 2 and the pinch valve are adaptive devices and are provided with working mechanisms, and after the consumables are loaded into the pipeline according to the diagram, the consumables can work under the condition of not damaging the sterile environment in the consumables;
the mother liquid bag 1 is used for storing the stock solution of the semi-finished biological medicine, can support the split charging of 10L-1000 mL mother liquid, and realizes the automatic split charging function of the biological medicine by wriggling, 2 working and opening the corresponding pinch valve;
the bag type filter 4 adopts a micropore design, so that most of impurities generated in the production process in the stock solution can be filtered, and the cleanliness of the final product during subpackaging is ensured to meet the standard;
in the using process of the bag type filter 4, the filtering efficiency is possibly reduced due to long-time use, at the moment, if the peristaltic pump 2 still works according to the original speed, larger pressure is possibly generated, and the bag type filter 4 has leakage risk, so that the disposable liquid pressure meter 3 is additionally arranged on a pipeline between the peristaltic pump 2 and the bag type filter 4, the pipeline wall pressure of the section of the pipeline is fed back in real time in the liquid pumping process, and when the feedback pressure is close to the maximum bearing pressure of the bag type filter 4, the speed of the peristaltic pump 2 is gradually reduced; when the feedback pressure reaches the maximum bearing pressure of the bag filter 4, the peristaltic pump 2 is directly stopped;
and (3) testing the tightness of consumables:
before the split charging is started, the integrity of consumable materials needs to be confirmed, the pressure in the main liquid line 9 is increased by opening the gas pipeline pinch valves and introducing air, the pressure feedback of the main liquid line 9 is carried out by the disposable gas pressure gauge 7, when the pressure of the main liquid line 9 reaches a set value, each pinch valve is closed for maintaining pressure, the pressure is fed back by the disposable gas pressure gauge 7 in real time, when the feedback pressure of the main liquid line 9 is reduced and exceeds a leakage standard, the fact that the main liquid line 9 leaks is proved, and the consumable materials need to be replaced; when the feedback pressure drop of the main liquid path 9 does not exceed the leakage standard, the consumable material passes the pressure maintaining test and can be used for aseptic split charging;
during pressure relief, pressure can be released through the air filters of the liquid storage bottles 12 by opening the pinch valves corresponding to any liquid storage bottle 12, and each liquid storage bottle cap is provided with the air filter 6 for balancing the pressure in the bottle;
gas purging:
in order to ensure the sub-packaging efficiency, the main liquid path 9 is generally larger in inner diameter, but after the main sub-packaging of the liquid is completed, the volume of the residual liquid in the liquid path is also larger, so that after the main sub-packaging is completed, the consumable supports the air to blow and sweep the residual liquid in the liquid path 9 to the designated liquid storage bottle 12, and the product loss is reduced;
the liquid storage bottle 12 is disassembled:
for the convenience of the 12 dismouting of stock solution bottle, 12 consumptive materials of stock solution bottle are designed for 6 a set of (also 2 a set of or 4 a set of), and every 12 main liquid routes of stock solution bottle of group are furnished with disposable quick connector for with other 12 quick connections of stock solution bottle of group, connect and can go on at C level environment.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. The utility model provides an aseptic large capacity liquid partial shipment consumptive material, includes mother liquor bag (1), its characterized in that: the mother liquid bag (1) is provided with a liquid pipeline (101), the liquid pipeline (101) is provided with a peristaltic pump (2), the liquid pipeline (101) is provided with a liquid pressure gauge (3) on the left side of the peristaltic pump (2), the liquid pipeline (101) is provided with a bag filter (4) on the left side of the liquid pressure gauge (3), the liquid pipeline (101) is provided with first pinch valves (5) on the rear sides of the bag filters (4) in a front-back symmetrical manner, the tail end of the liquid pipeline (101) is provided with an air filter (6), the liquid pipeline (101) is provided with liquid branch pipes (102) between the first pinch valves (5), the liquid branch pipes (102) are provided with gas-liquid pressure gauges (7), and the left end of the liquid branch pipes (102) is provided with an aseptic quick plug (8), main liquid way (9) are installed in the left side of aseptic fast plug (8), evenly be provided with cross four way connection (10) on main liquid way (9), the tail end of main liquid way (9) is provided with T type three way connection (11), the outer end of cross four way connection (10) and T type three way connection (11) all is connected with stock solution bottle (12), all be provided with second pinch valve (13) on cross four way connection (10) and T type three way connection (11).
2. The sterile large-capacity liquid dispensing consumable according to claim 1, characterized in that: the disposable liquid storage bottle is characterized in that the mother liquid bag (1), the liquid pipeline (101), the liquid pressure gauge (3), the bag type filter (4), the air filter (6), the liquid branch pipe (102), the gas-liquid pressure gauge (7), the sterile quick plug (8), the main liquid pipeline (9), the cross four-way joint (10), the T-shaped three-way joint (11) and the liquid storage bottle (12) are all disposable consumables.
3. The sterile large-capacity liquid dispensing consumable according to claim 1, characterized in that: an air filter (6) is also arranged on the bottle cap of the liquid storage bottle (12).
4. The sterile large-capacity liquid dispensing consumable according to claim 1, characterized in that: stock solution bottle (12) consumptive material can design for 6 a set ofly, and 2 a set of or 4 a set of do, and every stock solution bottle (12) of group and main liquid way (9) are furnished with disposable quick connector for with other stock solution bottle (12) high-speed joint of group, connect and can go on at C level environment.
5. The sterile large-capacity liquid dispensing consumable according to claim 1, characterized in that: the mother liquor bag (1) stores the stock solution of the semi-finished biological medicine product, and can support the split charging of mother liquor with the volume of 10L-1000 mL.
6. The sterile large-capacity liquid dispensing consumable according to claim 1, characterized in that: the bag filter (4) adopts a micropore design.
7. The sterile large-capacity liquid dispensing consumable according to claim 1, characterized in that: the peristaltic pump (2), the first pinch valve (5) and the second pinch valve (13) are adaptive equipment configuration working mechanisms.
8. The sterile large-capacity liquid dispensing consumable according to claim 1, characterized in that: and a pinch valve clamping position is arranged on the liquid pipeline (101) and matched with the first pinch valve (5), and a pinch valve clamping position is arranged on the cross four-way joint (10) and the T-shaped three-way joint (11) and matched with the second pinch valve (13).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202210279921.0A CN114715829A (en) | 2022-03-22 | 2022-03-22 | Sterile high-capacity liquid subpackaging consumable |
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Application Number | Priority Date | Filing Date | Title |
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CN202210279921.0A CN114715829A (en) | 2022-03-22 | 2022-03-22 | Sterile high-capacity liquid subpackaging consumable |
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CN114715829A true CN114715829A (en) | 2022-07-08 |
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CN202210279921.0A Pending CN114715829A (en) | 2022-03-22 | 2022-03-22 | Sterile high-capacity liquid subpackaging consumable |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115123985A (en) * | 2022-07-12 | 2022-09-30 | 深圳赛桥生物创新技术有限公司 | Pipeline emptying method and device |
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2022
- 2022-03-22 CN CN202210279921.0A patent/CN114715829A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115123985A (en) * | 2022-07-12 | 2022-09-30 | 深圳赛桥生物创新技术有限公司 | Pipeline emptying method and device |
CN115123985B (en) * | 2022-07-12 | 2023-08-11 | 深圳赛桥生物创新技术有限公司 | Pipeline emptying method and device |
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