CN114699163A - A radiofrequency ablation catheter with a cooling bladder - Google Patents
A radiofrequency ablation catheter with a cooling bladder Download PDFInfo
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- 238000001816 cooling Methods 0.000 title claims abstract description 65
- 238000007674 radiofrequency ablation Methods 0.000 title claims abstract description 20
- 239000007788 liquid Substances 0.000 claims abstract description 189
- 238000003032 molecular docking Methods 0.000 claims abstract description 3
- 230000010412 perfusion Effects 0.000 claims description 24
- 238000002679 ablation Methods 0.000 claims description 16
- 230000002262 irrigation Effects 0.000 claims 1
- 238000003973 irrigation Methods 0.000 claims 1
- 239000000110 cooling liquid Substances 0.000 abstract description 28
- 210000004204 blood vessel Anatomy 0.000 abstract description 25
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 5
- 239000002775 capsule Substances 0.000 abstract description 2
- 210000005036 nerve Anatomy 0.000 description 10
- 238000000034 method Methods 0.000 description 9
- 238000010586 diagram Methods 0.000 description 7
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 239000002826 coolant Substances 0.000 description 5
- 230000002889 sympathetic effect Effects 0.000 description 5
- 206010020772 Hypertension Diseases 0.000 description 4
- 230000003730 sympathetic denervation Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 239000002504 physiological saline solution Substances 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 239000003146 anticoagulant agent Substances 0.000 description 2
- 229940127219 anticoagulant drug Drugs 0.000 description 2
- 230000000747 cardiac effect Effects 0.000 description 2
- 230000002427 irreversible effect Effects 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
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- 230000001225 therapeutic effect Effects 0.000 description 2
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- 206010028851 Necrosis Diseases 0.000 description 1
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- 239000000498 cooling water Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 210000001174 endocardium Anatomy 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 210000001503 joint Anatomy 0.000 description 1
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- 230000008289 pathophysiological mechanism Effects 0.000 description 1
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- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
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- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00023—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids closed, i.e. without wound contact by the fluid
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- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
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Abstract
本发明提供一种具有冷却囊的射频消融导管,包括依次连接的导管端头和连接管;导管端头包括:设置有中空腔体的外管部、设置在中空腔体内的冷却囊以及用于固定外管部和冷却囊的连接件;冷却囊一端开口且具有弹性;连接件包括近端和远端,外管部和冷却囊与远端连接,近端用于与连接管对接;连接管内设置有液体进管、液体出管以及线管;利用这样的射频消融导管在射频电极工作时,冷却囊注入循环冷却液膨胀,紧密贴合电极内侧,并且对电极进行降温;尤其是对于呈螺旋状的四象限电极,冷却囊注水后能够适应螺旋形状在导管端头内部膨胀,并且紧密贴合电极内侧,对每个电极进行降温,控制电极工作状态下本身释放的热能,减小对血管的损伤。
The invention provides a radiofrequency ablation catheter with a cooling bladder, which includes a catheter end and a connecting pipe connected in sequence; the catheter end includes: an outer tube part provided with a hollow cavity, a cooling bladder set in the hollow cavity, and a The connecting piece for fixing the outer tube part and the cooling bladder; the cooling bladder is open at one end and has elasticity; the connecting piece includes a proximal end and a distal end, the outer tube part and the cooling bladder are connected with the distal end, and the proximal end is used for docking with the connecting tube; A liquid inlet tube, a liquid outlet tube and a wire tube are provided; when the RF electrode is used, the cooling bag is injected into the circulating cooling liquid to expand, closely fit the inside of the electrode, and cool the electrode; The four-quadrant electrode is shaped like a four-quadrant. After the cooling capsule is filled with water, it can adapt to the helical shape to expand inside the catheter end, and closely fit the inside of the electrode to cool down each electrode, control the heat energy released by the electrode itself in the working state, and reduce the damage to the blood vessel. damage.
Description
技术领域technical field
本发明涉及医疗设备技术领域,涉及一种具有冷却囊的射频消融导管。The invention relates to the technical field of medical equipment, and relates to a radiofrequency ablation catheter with a cooling bladder.
背景技术Background technique
难治性高血压是指在改善生活方式基础上应用可耐受的足够剂量且合理降压药物治疗至少4周后,血压值仍在目标水平之上,目前尚缺乏有效的治疗方案。去肾交感神经术作为难治性高血压的一种治疗手段,在病理生理机制上已被基础实验证实。Refractory hypertension refers to that blood pressure remains above the target level after at least 4 weeks of tolerable and adequate doses of reasonable antihypertensive drugs on the basis of improving lifestyle, and there is currently no effective treatment plan. Renal sympathetic denervation, as a treatment for refractory hypertension, has been confirmed by basic experiments in the pathophysiological mechanism.
去肾交感神经术经皮血管通过肾动脉对肾交感神经进行消融,去肾交感神经术可以有效减少全身和肾局部的交感活性,同时对难治性高血压病有较好的治疗作用。Renal sympathetic denervation is a percutaneous ablation of the renal sympathetic nerve through the renal artery. Renal sympathetic denervation can effectively reduce the sympathetic activity of the whole body and the local kidney, and has a good therapeutic effect on refractory hypertension.
但是,在血管中通过导管引导电极对血管外的神经进行消融的过程中,电极释放的能够不具有靶向性,释放的热能会对血管造成不可逆的损伤,轻者导致血管狭窄,患者需要终身服用抗凝药;重者会导致血管闭合,造成更为严重的损伤。However, in the process of ablating the nerve outside the blood vessel through the catheter guide electrode in the blood vessel, the release of the electrode may not be targeted, and the heat energy released will cause irreversible damage to the blood vessel. Take anticoagulants; in severe cases, blood vessels can close, causing more serious damage.
发明内容SUMMARY OF THE INVENTION
为了实现上述目的,本发明采用的技术方案是:In order to achieve the above object, the technical scheme adopted in the present invention is:
一种具有冷却囊的射频消融导管,包括依次连接的导管端头和连接管;A radiofrequency ablation catheter with a cooling bladder, comprising a catheter tip and a connecting pipe connected in sequence;
导管端头包括:设置有中空腔体的外管部、设置在中空腔体内的冷却囊以及用于固定外管部和冷却囊的连接件;The catheter tip includes: an outer tube part provided with a hollow cavity, a cooling bladder set in the hollow cavity, and a connecting piece for fixing the outer tube part and the cooling bladder;
其中,冷却囊一端开口且具有弹性;连接件包括近端和远端,外管部和冷却囊与远端连接,近端用于与连接管对接;连接管内设置有液体进管、液体出管以及线管;One end of the cooling bladder is open and elastic; the connecting piece includes a proximal end and a distal end, the outer tube part and the cooling bladder are connected to the distal end, and the proximal end is used for docking with the connecting pipe; the connecting pipe is provided with a liquid inlet pipe and a liquid outlet pipe and conduit;
连接件设置有液体流入通道、液体流出通道以及线通道;液体流入通道、液体流出通道、线通道分别与液体进管、液体出管、线管连接。The connecting piece is provided with a liquid inflow channel, a liquid outflow channel and a line channel; the liquid inflow channel, the liquid outflow channel and the line channel are respectively connected with the liquid inlet pipe, the liquid outlet pipe and the line pipe.
优选的,所述外管部外侧设置有一个或多个消融电极,每个消融电极分别连接有电极线;Preferably, one or more ablation electrodes are disposed on the outside of the outer tube portion, and each ablation electrode is respectively connected with an electrode wire;
所述电极线沿中空腔体内表面向连接件延伸,并通过线通道穿过连接件进入线管。The electrode wire extends toward the connecting piece along the inner surface of the hollow cavity, and enters the wire tube through the wire channel through the connecting piece.
优选的,所述连接件的远端设置有延长管,延长管与液体进管连接,延长管长度小于中空腔体的长度。Preferably, the distal end of the connecting piece is provided with an extension tube, the extension tube is connected with the liquid inlet tube, and the length of the extension tube is smaller than the length of the hollow cavity.
优选的,所述液体流入通道为直筒状,并且贯穿连接件的远端和近端;Preferably, the liquid inflow channel is straight and runs through the distal end and the proximal end of the connector;
所述液体流出通道贯穿连接件的远端和近端,并且液体流出通道远端的截面尺寸大于近端的截面尺寸。The liquid outflow channel runs through the distal end and the proximal end of the connector, and the cross-sectional dimension of the distal end of the liquid outflow channel is larger than the cross-sectional dimension of the proximal end.
优选的,所述液体流出通道为筒状,液体流出通道近端截面尺寸小于液体流入通道截面尺寸。Preferably, the liquid outflow channel is cylindrical, and the cross-sectional dimension of the proximal end of the liquid outflow channel is smaller than the cross-sectional dimension of the liquid inflow channel.
优选的,所述连接管套接在连接件外,连接管内包括液体进管腔、液体出管腔以及线管腔;Preferably, the connecting pipe is sleeved outside the connecting piece, and the connecting pipe includes a liquid inlet lumen, a liquid outlet lumen and a wire lumen;
液体进管腔与液体流入通道连接;液体出管腔与液体流出通道连接,线管腔与线通道连接。The liquid inlet lumen is connected with the liquid inflow channel; the liquid outlet lumen is connected with the liquid outflow channel, and the line lumen is connected with the line channel.
优选的,所述液体流出通道为圆环形,从液体流入通道内部环绕液体流入通道;Preferably, the liquid outflow channel is annular, and surrounds the liquid inflow channel from the inside of the liquid inflow channel;
圆环形液体流出通道远端设置有斜面,所述斜面在液体流出通道远端入口处形成向外放射状的开口,使得液体流出通道远端的截面尺寸大于近端的截面尺寸。The distal end of the annular liquid outflow channel is provided with an inclined surface, and the inclined surface forms an outward radial opening at the entrance of the distal end of the liquid outflow channel, so that the cross-sectional dimension of the distal end of the liquid outflow channel is larger than that of the proximal end.
优选的,所述连接管内部中空,套接在连接件外;Preferably, the connecting pipe is hollow inside and is sleeved outside the connecting piece;
连接管内设置有液体进管、液体出管、线管,液体出管套接在液体进管外,液体进管与液体流入通道连接,液体出管与液体流出通道连接,线管与线通道连接。The connecting pipe is provided with a liquid inlet pipe, a liquid outlet pipe and a line pipe, the liquid outlet pipe is sleeved outside the liquid inlet pipe, the liquid inlet pipe is connected with the liquid inflow channel, the liquid outlet pipe is connected with the liquid outflow channel, and the line pipe is connected with the line channel .
优选的,所述连接件内设置有与液体流入通道和/或液体流出通道连接的灌注通道;Preferably, a perfusion channel connected to the liquid inflow channel and/or the liquid outflow channel is provided in the connector;
所述灌注通道所在平面垂直于液体流入通道的轴线;且灌注通道为圆环形;The plane where the perfusion channel is located is perpendicular to the axis of the liquid inflow channel; and the perfusion channel is annular;
所述连接件侧面设置有灌注孔,灌注孔连接灌注通道并贯穿连接件侧面。The side of the connector is provided with a perfusion hole, and the perfusion hole is connected to the perfusion channel and penetrates through the side of the connector.
优选的,所述连接管的末端设置有液体流出阀,所述液体流出阀通过液体出管与液体流出通道连接;Preferably, the end of the connecting pipe is provided with a liquid outflow valve, and the liquid outflow valve is connected to the liquid outflow channel through the liquid outlet pipe;
所述液体流出阀上设置有流量开关,所述流量开关能够调节液体出管的液体流量大小。A flow switch is provided on the liquid outflow valve, and the flow switch can adjust the liquid flow rate of the liquid outlet pipe.
本发明的有益效果体现在,提供一种具有冷却囊的射频消融导管,在射频电极工作时,冷却囊注入循环冷却液膨胀,紧密贴合电极内侧,并且对电极进行降温;尤其是对于呈螺旋状的四象限电极,冷却囊注水后能够适应螺旋形状在导管端头内部膨胀,并且紧密贴合电极内侧,对每个电极进行降温,控制电极工作状态下本身释放的热能,减小对血管的损伤。The beneficial effect of the present invention is to provide a radio frequency ablation catheter with a cooling bladder. When the radio frequency electrode is working, the cooling bladder is injected with circulating cooling liquid to expand, closely fit the inside of the electrode, and cool the electrode; The four-quadrant electrode is shaped like a four-quadrant. After the cooling capsule is filled with water, it can adapt to the helical shape to expand inside the catheter end, and it closely fits the inside of the electrode to cool down each electrode, control the heat energy released by the electrode itself in the working state, and reduce the damage to the blood vessel. damage.
另一方面,射频电极在工作时可以选择性的通过调节流量开关来增加冷却液压力,进而使得冷却液从灌注孔中喷出,生理盐水流入血液,起降温效果;其后可以调节流量开关减小冷却液压力,停止向血液中灌注生理盐水。On the other hand, the RF electrode can selectively increase the coolant pressure by adjusting the flow switch during operation, so that the coolant is ejected from the perfusion hole, and the physiological saline flows into the blood, which has a cooling effect; then the flow switch can be adjusted to reduce the pressure. The low coolant pressure stops the perfusion of saline into the blood.
附图说明Description of drawings
图1为本发明实施例的一种具有冷却囊的射频消融导管结构示意图;1 is a schematic structural diagram of a radiofrequency ablation catheter with a cooling bladder according to an embodiment of the present invention;
图2为本发明实施例的导管端头以及连接件的结构示意图;2 is a schematic structural diagram of a catheter tip and a connector according to an embodiment of the present invention;
图3为本发明实施例的导管端头以及连接件剖视图;3 is a cross-sectional view of a catheter tip and a connector according to an embodiment of the present invention;
图4为本发明实施例的连接件与带腔体的连接管连接部示意图;4 is a schematic diagram of a connecting part of a connector and a connecting pipe with a cavity according to an embodiment of the present invention;
图5为本发明实施例的连接件与中空的连接管连接部示意图;FIG. 5 is a schematic diagram of a connecting part of a connecting piece and a hollow connecting pipe according to an embodiment of the present invention;
图6为本发明实施例的连接件剖视图;6 is a cross-sectional view of a connector according to an embodiment of the present invention;
图7为本发明实施例的连接件以及延长管的剖视图;7 is a cross-sectional view of a connector and an extension tube according to an embodiment of the present invention;
图8为本发明实施例的螺旋形导管示意图;8 is a schematic diagram of a helical conduit according to an embodiment of the present invention;
图9为本发明实施例的螺旋导管剖视图以及内部的冷却囊结构示意图;9 is a cross-sectional view of a spiral conduit and a schematic structural diagram of an internal cooling bladder according to an embodiment of the present invention;
图10为本发明实施例的灌注微孔结构示意图。FIG. 10 is a schematic diagram of a perfusion microporous structure according to an embodiment of the present invention.
具体实施方式Detailed ways
下面结合附图及本发明的实施例对本发明的方法作进一步详细的说明。The method of the present invention will be described in further detail below with reference to the accompanying drawings and the embodiments of the present invention.
实施例1Example 1
参阅图1、图2,本发明实施例提供一种具有冷却囊112的射频消融导管1,包括依次连接的导管端头11和连接管12;Referring to FIG. 1 and FIG. 2 , an embodiment of the present invention provides a
导管端头11包括:设置有中空腔体的外管部111、设置在中空腔体内的冷却囊112以及用于固定外管部111和冷却囊112的连接件13;The
其中,冷却囊112一端开口且具有弹性;连接件13包括近端和远端,外管部111和冷却囊112与远端连接,近端用于与连接管12对接;连接管12内设置有液体进管121、液体出管122以及线管123;One end of the
连接件13设置有液体流入通道131、液体流出通道132以及线通道133;液体流入通道131、液体流出通道132、线通道133分别与液体进管121、液体出管122、线管123连接。The
射频消融术是将电极2导管经静脉或动脉血管送入特定部位,释放射频电流破坏组织,达到治疗疾病的目的。Radiofrequency ablation is to send the
例如,去肾交感神经术经皮血管通过肾动脉对肾交感神经进行消融,去肾交感神经术可以有效减少全身和肾局部的交感活性,同时对难治性高血压病有较好的治疗作用。For example, renal sympathetic denervation can effectively reduce the sympathetic activity of the whole body and local kidney, and has a good therapeutic effect on refractory hypertension. .
再例如,心脏射频消融术是将电极2导管经静脉或动脉血管送入心腔特定部位,释放射频电流导致局部心内膜及心内膜下心肌凝固性坏死,达到阻断快速心律失常异常传导束和起源点的介入性技术。For another example, cardiac radiofrequency ablation is to send the
但是,在血管中通过导管引导电极2对血管外的神经进行消融的过程中,电极2释放的能够不具有靶向性,释放的热能会对血管造成不可逆的损伤,轻者导致血管狭窄,患者需要终身服用抗凝药;重者会导致血管闭合,造成更为严重的损伤。However, in the process of ablating the nerves outside the blood vessel through the
本实施例的导管端头11用于安装电极2,具体的,电极2嵌入式安装在外管部111外侧,电极2内部突出外管部111的内表面,外管部111的中空腔体内设置有冷却囊112,冷却囊112一端开口,开口部固定在连接件13的远端。The
连接件13上设置有液体流入通道131和液体流出通道132,液体流入通道131和液体流出通道132均贯穿连接件13,且连接冷却囊112内部和连接件13近端。The
在使用过程中,将导管端头11经血管输送到需要进行消融的位置,并且将冷却液通过液体流入通道131输送进入冷却囊112,并从液体流出通道132流出,进行循环。During use, the
冷却囊112受液体压力膨胀,冷却囊112具有密闭性,冷却液不会渗出直接与电极2接触。膨胀后的冷却囊112紧密贴合外管部111的内部,同时还能够贴合电极2内侧,对每个电极2进行降温,控制电极2工作状态下本身释放的热能,减小对血管的损伤。The cooling
相比于传统的带有冷却功能的电极2,冷却液在管道中进行循环,进能够通过管道壁间接接触电极2,电极2瞬间发热量大,间接接触降温的方式不能够达到较好的降温效果。Compared with the
本实施例的冷却囊112壁薄且具有可塑性,冷却液压力能够使冷却囊112膨胀,并紧密贴合电极2,对电极2进行降温,接触面积大且降温速度快。The cooling
在具体实现过程中,如图1所示,消融导管1包括设置在头部导管端头11的电极2、连接管12以及操作手柄9,消融导管1经皮进入血管,可以通过导丝的引导,在血管中行进到需要进行消融的位置,然后启动电极2进行消融,本实施例的电极线、液体进管121、液体出管122均通过连接管12连接到操作手柄9,操作手柄9上设置有能够连接电极2控制器的电极2接口、连接到循环泵的冷却液进水口和冷却液出水口。上述的电极2接口、冷却液进水口以及冷却液出水口在图中未示出。In the specific implementation process, as shown in FIG. 1 , the
进一步,所述外管部111外侧设置有一个或多个消融电极2,每个消融电极2分别连接有电极线;Further, one or
所述电极线沿中空腔体内表面向连接件13延伸,并通过线通道133穿过连接件13进入线管123。The electrode wire extends toward the connecting
本实施例中,针对上述的去肾交感神经术,肾交感神经遍布血管四周。因此,导管被设计成螺旋状,四象限分别设置一个或多个电极2对血管四周的神经进行同时消融或者选择某个方向进行消融。In this embodiment, for the above-mentioned renal sympathetic nerve removal, the renal sympathetic nerves are distributed around the blood vessels. Therefore, the catheter is designed in a spiral shape, and one or
螺旋状的导管相比于直筒状的导管更靠近血管壁,为了防止电极2产生的热量对血管的损伤,需要快速对电极2进行降温,传统的在管道内循环冷却水进行降温的方式可能导致电极2产生的热量损伤血管。The helical catheter is closer to the blood vessel wall than the straight catheter. In order to prevent the heat generated by the
如图8、图9所示,图8示出本发明另一种实施例的螺旋状外管部111a,螺旋状外管部111a上包括4个电极2,4个电极2分别向空间的四个方向,也就是四象限方向。As shown in FIG. 8 and FIG. 9 , FIG. 8 shows a spiral
在具体实现过程中,在神经密集区域不能识别目标神经,可以通过分别控制四象限电极2释放较弱的能量刺激神经并检测生理指标参数,找到目标神经密集的区域释放较强能量对目标神经进行消融。In the specific implementation process, the target nerve cannot be identified in the nerve-dense area, and the four-
由此可见,螺旋形外管部111a以及四象限电极2能够在多个方向设置电极2并分别控制,使得射频消融具有指向性,只针对目标神经密集的区域进行消融。It can be seen that the helical
但是,螺旋形外管部111a相比于直筒状的导管更靠近血管壁,为了防止电极2产生的热量对血管的损伤,需要快速对电极2进行降温,如图9所示,本实施的壁薄且具有延展性的冷却囊112能够设置在螺旋形外管部111a内,通入冷却液后受液体压力膨胀,并且紧密贴合电极2内侧,对每个电极2进行降温,控制电极2工作状态下本身释放的热能,减小对血管的损伤。However, the helical
在具体实现过程中,电极线连接电极2,用于为电极2供电并控制电极2开闭,本实施例的消融导管1电极线沿外管部111的中空腔体内表面设置,并通过线通道133穿过连接件13,再经过线管123连接到体外的控制器。In the specific implementation process, the electrode wire is connected to the
进一步,如图7所示,所述连接件13的远端设置有延长管3,延长管3与液体进管121连接,延长管3长度小于中空腔体的长度。Further, as shown in FIG. 7 , the distal end of the
本实施例中,延长管3用于将冷却液输送到冷却囊112的远端,低温的冷却液经过全部电极2,与电极2交换热量,升温后的冷却液在冷却囊112内向连接件13流动,通过液体流出通道132再经液体出管122流入体外的循环装置,也可以在重新降温后进入液体进管121形成循环冷却。In this embodiment, the
对于上述的螺旋状外管部111a可以匹配的设置螺旋状或者弯曲的,且能够适应螺旋状的弯曲的延长管3,将冷却液输送到冷却囊112的远端。For the above-mentioned helical
进一步,所述液体流入通道131为直筒状,并且贯穿连接件13的远端和近端;Further, the
所述液体流出通道132贯穿连接件13的远端和近端,并且液体流出通道132远端的截面尺寸大于近端的截面尺寸。The
本实施例中,液体流出通道132远端的截面尺寸大于近端的截面尺寸,使得冷却囊112在自然状态下处于未膨胀的状态,液体流入通道131截面尺寸大,使得液体流入和液体流出产生压力差。In this embodiment, the cross-sectional dimension of the distal end of the
压力差能够使得冷却囊112膨胀,紧密贴合电极2内侧,并且对电极2进行降温;尤其是对于呈螺旋状的四象限电极2,冷却囊112注水后能够适应螺旋形状在导管端头11内部膨胀,并且紧密贴合电极2内侧,对每个电极2进行降温,控制电极2工作状态下本身释放的热能,减小对血管的损伤。The pressure difference can make the cooling
进一步,所述液体流出通道132为筒状,液体流出通道132近端截面尺寸小于液体流入通道131截面尺寸。Further, the
图3示出一种液体流入通道131和液体流出通道132的布置方式,具体的,如图3所示,连接件13远端用于对接冷却囊112,连接件13的远端设置有环形固定板4,用于加紧冷却囊112的开口。FIG. 3 shows an arrangement of the
连接件13的近端用于对接连接管12,液体流入通道131和液体流出通道132在连接件13近端是平行布置,分别对接连接管12的两个腔体,分别用于冷却液流入和流出。The proximal end of the connecting
液体流入通道131和液体流出通道132在远端是两个同心的管道,液体流入管道通过中心的管道将冷却液注入冷却囊112;液体流出管道通过外部的管道将冷却液输出。The
进一步,所述连接管12套接在连接件13外,连接管12内包括液体进管121腔、液体出管122腔以及线管123腔;Further, the connecting
液体进管121腔与液体流入通道131连接;液体出管122腔与液体流出通道132连接,线管123腔与线通道133连接。The cavity of the
如图4所示,本实施例的连接管12为实心,且内部设置有液体进管121腔、液体出管122腔以及线管123腔。As shown in FIG. 4 , the connecting
流入的冷却液、流出的冷却液直接通过连接管12内部的腔体连接手柄和导管端头11。The inflowing cooling liquid and the outflowing cooling liquid directly connect the handle and the
进一步,所述液体流出通道132为圆环形,从液体流入通道131内部环绕液体流入通道131;Further, the
圆环形液体流出通道132远端设置有斜面5,所述斜面5在液体流出通道132远端入口处形成向外放射状的开口,使得液体流出通道132远端的截面尺寸大于近端的截面尺寸。The distal end of the annular
如图3所示,液体流入通道131和液体流出通道132在远端是两条同心的管道,液体流出管道设置有斜面5,呈喇叭状开口,使得液体流出通道132远端的截面尺寸大于近端的截面尺寸,进而在保证流出的冷却液能够导入液体流出通道132,又能够使得液体流出通道132截面尺寸减小,产生压力差。As shown in FIG. 3 , the
进一步,所述连接管12内部中空,套接在连接件13外;Further, the connecting
连接管12内设置有液体进管121、液体出管122、线管123,液体出管122套接在液体进管121外,液体进管121与液体流入通道131连接,液体出管122与液体流出通道132连接,线管123与线通道133连接。The connecting
图5、图6示出另一种液体流入通道131和液体流出通道132的布置方式,具体的,如图6所示,液体流入通道131和液体流出通道132在远端和近端都是同心的管道,位于中心的液体流入管道通过侧面与液体流出通道132内壁的支撑件6支撑。5 and 6 show another arrangement of the
如图5所示,另一种连接管12为内部中空,连接管12内设置的液体进管121、液体出管122、线管123都是独立的管道,液体进管121套接在液体出管122外部。As shown in FIG. 5 , another connecting
本实施的连接管12内部中空,减小了循环的冷却液对血管温度的影响。进一步来说,相互套接的液体进管121和液体出管122还能够减小血液温度对冷却液温度的影响。The connecting
进一步,所述连接件13内设置有与液体流入通道131和/或液体流出通道132连接的灌注通道8;Further, a perfusion channel 8 connected to the
所述灌注通道8所在平面垂直于液体流入通道131的轴线;且灌注通道8为圆环形;The plane where the perfusion channel 8 is located is perpendicular to the axis of the
所述连接件13侧面设置有灌注孔81,灌注孔81连接灌注通道8并贯穿连接件13侧面。A
所述连接管12的末端设置有液体流出阀,所述液体流出阀通过液体出管122与液体流出通道132连接;The end of the connecting
所述液体流出阀上设置有流量开关7,所述流量开关7能够调节液体出管122的液体流量大小。A
所述连接管12的末端设置有液体流出阀,所述液体流出阀通过液体出管122与液体流出通道132连接;The end of the connecting
所述液体流出阀上设置有流量开关7,所述流量开关7能够调节液体出管122的液体流量大小。A
如图10所示,灌注通道8可以与液体流入通道131连接,还可以与液体流出通道132连接,本实施例灌注通道8与液体流出通道132连接。As shown in FIG. 10 , the perfusion channel 8 can be connected to the
灌注孔81环绕在连接件13的外侧,冷却液通过液体流出通道132进入灌注孔81,冷却循环畅通的情况下由于灌注孔81直径小,冷却液不会从灌注孔81流出,或者仅能够流出微量的冷却液。The filling
本实施例的冷却液可以是经过降温后的生理盐水。The cooling liquid in this embodiment may be physiological saline that has been cooled down.
射频电极2在工作时可以选择性的通过调节流量开关7来增加冷却液压力,进而使得冷却液从灌注孔81中喷出,生理盐水流入血液,起降温效果;其后可以调节流量开关7减小冷却液压力,停止向血液中灌注生理盐水。The
在本发明的实施例的描述中,需要理解的是,术语“上”、“下”、“前”、“后”、“左”、“右”、“坚直”、“水平”、“中心”、“顶”、“底”、“顶部”、“底部”、“内”、“外”、“内侧”、“外侧”等指示的方位或位置关系为基于附图所示的方位或位置关系,仅是为了使于描述本发明和简化描述,而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此不能理解为对本发明的限制。In the description of the embodiments of the present invention, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "straight", "horizontal", " The orientation or positional relationship indicated by center, top, bottom, top, bottom, inner, outer, inner, outer, etc. is based on the orientation shown in the drawings or The positional relationship is only for the purpose of describing the present invention and simplifying the description, rather than indicating or implying that the indicated device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present invention.
在本发明的实施例的描述中,需要说明的是,除非另有明确的规定和限定,术语“安装”、“相连”、“连接”、“组装”应做广义理解,例如,可以是固定连接,也可以是可拆卸连接,或一体地连接;可以是直接相连,也可以通过中间媒介间接相连,可以是两个元件内部的连通。对于本领域的普通技术人员而言,可以具体情况理解上述术语在本发明中的具体含义。In the description of the embodiments of the present invention, it should be noted that, unless otherwise expressly specified and limited, the terms "installed", "connected", "connected" and "assembled" should be understood in a broad sense, for example, it may be fixed The connection can also be a detachable connection, or an integral connection; it can be a direct connection, or an indirect connection through an intermediate medium, and it can be the internal communication of the two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood in specific situations.
尽管已经示出和描述了本发明的实施例,对于本领域的普通技术人员而言,可以理解在不脱离本发明的原理和精神的情况下可以对这些实施例进行多种变化、修改、替换和变型,本发明的范围由所附权利要求及其等同物限定。Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, and substitutions can be made in these embodiments without departing from the principle and spirit of the invention and modifications, the scope of the present invention is defined by the appended claims and their equivalents.
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CN203029378U (en) * | 2012-12-13 | 2013-07-03 | 乐普(北京)医疗器械股份有限公司 | Balloon electrode renal artery radiofrequency ablation catheter |
CN203354639U (en) * | 2013-04-26 | 2013-12-25 | 刘宗军 | Cold brine perfusion type electrical ablation balloon catheter provided with micropores for renal sympathetic denervation |
CN203815580U (en) * | 2014-04-22 | 2014-09-10 | 上海微创电生理医疗科技有限公司 | Renal artery radio-frequency ablation electrode catheter |
CN111741734A (en) * | 2018-01-16 | 2020-10-02 | 埃尔医学股份有限公司 | Device, system and method for thermal treatment of body tissue |
CN108309444A (en) * | 2018-03-30 | 2018-07-24 | 广东百德医疗有限公司 | A kind of fluid injection and wicking structure suitable for microwave melt needle |
CN113116512A (en) * | 2019-12-31 | 2021-07-16 | 上海微创电生理医疗科技股份有限公司 | Ablation electrode assembly and ablation catheter |
CN112244994A (en) * | 2020-11-11 | 2021-01-22 | 乐普(北京)医疗器械股份有限公司 | A radiofrequency ablation catheter and endovascular interventional therapy system with cooling function |
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