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CN114632217A - An automatic drug delivery device based on micro-displacement sensor - Google Patents

An automatic drug delivery device based on micro-displacement sensor Download PDF

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Publication number
CN114632217A
CN114632217A CN202210198776.3A CN202210198776A CN114632217A CN 114632217 A CN114632217 A CN 114632217A CN 202210198776 A CN202210198776 A CN 202210198776A CN 114632217 A CN114632217 A CN 114632217A
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drug delivery
photoelectric switch
micro
displacement sensor
stepping motor
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CN114632217B (en
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冯勇通
徐正平
刘祎
李原
吴炎凡
牛群
曹炜
葛阳
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Chongqing Guoke Medical Technology Development Co ltd
Suzhou Institute of Biomedical Engineering and Technology of CAS
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Chongqing Guoke Medical Technology Development Co ltd
Suzhou Institute of Biomedical Engineering and Technology of CAS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804Flow controllers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16877Adjusting flow; Devices for setting a flow rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B21/00Measuring arrangements or details thereof, where the measuring technique is not covered by the other groups of this subclass, unspecified or not relevant
    • G01B21/02Measuring arrangements or details thereof, where the measuring technique is not covered by the other groups of this subclass, unspecified or not relevant for measuring length, width, or thickness
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M2005/14208Pressure infusion, e.g. using pumps with a programmable infusion control system, characterised by the infusion program
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
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  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • General Physics & Mathematics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

本发明公开了一种基于微位移传感器的自动给药装置,包括基板以及固定于基板上的电机安装架、直线导轨、注射器安装架、终点光电开关安装座和零位光电开关安装座;注射器安装架上固定注射器,注射器推杆尾部安装电涡流传感器被测物;电机安装架上安装固定梯形丝杆步进电机,直线导轨上安装滚珠滑块,步进电机的梯形丝杆上同轴装有梯形丝杆滑座,滚珠滑块和梯形丝杆滑座均与给药推头相连接;零位光电开关安装座、终点光电开关安装座沿注射器推杆推药注射的方向依次设置,其上分别安装零位光电开关、终点光电开关。本发明能自主测量给药推头与注射器推杆之间相对位置信息,在两者之间距离到达指定范围后自动切换给药推头运行速度,提高了给药工作效率。

Figure 202210198776

The invention discloses an automatic drug delivery device based on a micro-displacement sensor. The syringe is fixed on the rack, the eddy current sensor is installed at the tail of the syringe push rod; the stepper motor is installed on the motor mounting frame, and the ball slider is installed on the linear guide. The trapezoidal screw sliding seat, the ball sliding block and the trapezoidal screw sliding seat are all connected with the dosing pusher; the zero-position photoelectric switch mounting seat and the end-point photoelectric switch mounting seat are arranged in sequence along the direction of the injection of the syringe push rod, on which Install the zero-position photoelectric switch and the end-point photoelectric switch respectively. The invention can autonomously measure the relative position information between the drug delivery pusher and the syringe pusher, and automatically switch the running speed of the drug delivery pusher when the distance between the two reaches a specified range, thereby improving the drug delivery work efficiency.

Figure 202210198776

Description

一种基于微位移传感器的自动给药装置An automatic drug delivery device based on micro-displacement sensor

技术领域technical field

本发明属于给药技术领域,特别是一种基于微位移传感器的自动给药装置。The invention belongs to the technical field of drug delivery, in particular to an automatic drug delivery device based on a micro-displacement sensor.

背景技术Background technique

在临床上,对重症患者应用特定药物时须严格控制给药速度,确保均匀、极低速给药,由此需要采用自动给药装置。当注射器固定后,注射器推杆尾部位置随待注射药量不同而变化。当前的自动给药装置需要医护人员人为地将给药推头推至与注射器推杆尾部相接触后,再启动给药程序,即整个过程还需医护人员干预,未实现全自动给药;如果在固定注射器后即启动给药程序,此时给药推头距离注射器推杆尾部还有一段距离,因该距离未知,为保证用药安全,给药推头若以给药速度进行运动,直至运动到与注射器推杆尾部接触后才真正将药物注射至患者体内,无法做到及时用药,延误患者治疗时机。Clinically, when applying specific drugs to critically ill patients, the dosing speed must be strictly controlled to ensure uniform and extremely low-speed dosing, which requires the use of automatic dosing devices. When the syringe is fixed, the position of the tail of the syringe push rod changes with the amount of medicine to be injected. The current automatic drug delivery device requires medical staff to manually push the drug delivery pusher to contact the tail of the syringe push rod, and then start the drug delivery procedure, that is, the entire process requires the intervention of medical staff, and does not achieve fully automatic drug delivery; if After fixing the syringe, the administration procedure is started. At this time, there is still a distance between the administration pusher and the tail of the syringe pusher. Because the distance is unknown, in order to ensure the safety of medication, if the administration pusher moves at the administration speed, it will not move until it moves. Only after contact with the tail of the syringe push rod is the drug injected into the patient's body, it cannot be administered in time and the patient's treatment time is delayed.

发明内容SUMMARY OF THE INVENTION

本发明的目的在于解决重症患者应用特定药物时及时用药及严格控制给药速度之间的矛盾,提供一种自动给药装置,使得系统快速启动,在给药推头与注射器推杆之间距离达到数微米范围内时,改变给药推头速度至设定给药速度,在满足及时用药的同时,严格控制给药速度,保证用药安全。本发明能实现自主测量给药推头与注射器推杆之间相对位置信息,在两者之间距离到达指定范围后自动切换给药推头运行速度,由此提高给药工作效率。The purpose of the present invention is to solve the contradiction between timely drug administration and strict control of drug administration speed when critically ill patients use specific drugs, and to provide an automatic drug delivery device, which enables the system to start quickly, and the distance between the drug delivery pusher and the syringe push rod is reduced. When it reaches the range of several microns, change the speed of the dosing pusher to the set dosing speed, and strictly control the dosing speed to ensure the safety of medication while satisfying the timely medication. The invention can independently measure the relative position information between the drug delivery pusher and the syringe pusher, and automatically switch the running speed of the drug delivery pusher when the distance between the two reaches a specified range, thereby improving the drug delivery work efficiency.

实现本发明目的的技术解决方案为:一种基于微位移传感器的自动给药装置,所述装置包括基板,以及固定于基板上的电机安装架、直线导轨、注射器安装架、终点光电开关安装座和零位光电开关安装座;所述注射器安装架上固定注射器,注射器推杆尾部安装电涡流传感器被测物;所述电机安装架上安装固定梯形丝杆步进电机,直线导轨上安装滚珠滑块,步进电机的梯形丝杆上同轴装有梯形丝杆滑座,所述滚珠滑块和梯形丝杆滑座均与给药推头相连接;所述零位光电开关安装座、终点光电开关安装座沿注射器推杆推药注射的方向依次设置,其上分别安装零位光电开关、终点光电开关;The technical solution to achieve the purpose of the present invention is: an automatic drug delivery device based on a micro-displacement sensor, the device includes a base plate, and a motor mounting frame, a linear guide rail, a syringe mounting frame, and a terminal photoelectric switch mounting seat fixed on the base plate and zero-position photoelectric switch mounting seat; the syringe is fixed on the syringe mounting frame, and the eddy current sensor is installed at the tail of the syringe push rod; the trapezoidal screw stepping motor is installed on the motor mounting frame, and the ball slide is installed on the linear guide. The trapezoidal lead screw of the stepping motor is coaxially equipped with a trapezoidal lead screw slide, and the ball slide block and the trapezoidal lead lead slide are both connected with the drug delivery pusher; the zero position photoelectric switch mount, the end point The photoelectric switch mounting bases are arranged in sequence along the direction of the injector push rod to push the medicine injection, and the zero position photoelectric switch and the end photoelectric switch are respectively installed on it;

装置上电后进行初始化,驱动梯形丝杆步进电机转动,进而通过梯形丝杆滑座、滚珠滑块带动给药推头沿直线导轨朝零位光电开关方向运动,当给药推头运动至零位光电开关时停止,完成装置初始化;自动给药装置启动工作时,梯形丝杆步进电机带动给药推头以速度V1向注射器推杆方向移动,安装在给药推头内部的微位移传感器探头实时探测给药推头端面与注射器推杆尾部安装的电涡流传感器被测物之间的距离,即给药推头端面与注射器推杆端面的距离,当距离达到指定范围后,给药推头以给药所需的速度V2继续推动注射器推杆;当终点光电开关输出电平发生翻转时,梯形丝杆步进电机运动方向改变,以速度V1向零位光电开关方向运动,最终停在零位,则装置完成一次自动给药;其中V1>>V2。After the device is powered on, it is initialized and drives the trapezoidal screw stepping motor to rotate, and then drives the drug delivery pusher to move along the linear guide towards the zero-position photoelectric switch through the trapezoidal screw slide and ball slider. When the zero position photoelectric switch stops, the initialization of the device is completed; when the automatic drug delivery device starts to work, the trapezoidal screw stepping motor drives the drug delivery pusher to move in the direction of the syringe pusher at the speed V1, and the micro-displacement inside the drug delivery pusher is installed. The sensor probe detects the distance between the end face of the drug delivery pusher and the measured object of the eddy current sensor installed at the tail of the syringe pusher in real time, that is, the distance between the end face of the drug delivery pusher and the end face of the syringe pusher. When the distance reaches the specified range, the drug is administered. The push head continues to push the syringe push rod at the speed V2 required for the drug administration; when the output level of the photoelectric switch at the end point is reversed, the moving direction of the trapezoidal screw stepping motor changes, and moves in the direction of the zero position photoelectric switch at the speed V1, and finally stops. At the zero position, the device completes an automatic drug administration; where V1>>V2.

进一步地,该装置还包括系统控制器,该系统控制器包括主控制器、用户操控模块、信息显示模块、步进电机驱动器、微位移传感器处理板、电压比较器及电位计;Further, the device also includes a system controller, which includes a main controller, a user control module, an information display module, a stepping motor driver, a micro-displacement sensor processing board, a voltage comparator and a potentiometer;

所述主控制器通过控制步进电机驱动器带动梯形丝杆步进电机做旋转运动;The main controller drives the trapezoidal lead screw stepping motor to rotate by controlling the stepping motor driver;

所述微位移传感器探头与微位移传感器处理板相连接,微位移传感器处理板输出的模拟信号经电压比较器转换成数字电平后进入主控制器,电压比较器的比较电压由电位计进行调节;The micro-displacement sensor probe is connected with the micro-displacement sensor processing board. The analog signal output by the micro-displacement sensor processing board is converted into a digital level by a voltage comparator and then enters the main controller. The comparison voltage of the voltage comparator is adjusted by a potentiometer. ;

所述零位光电开关、终点光电开关输出的数字信号直接进入主控制器;The digital signal output by the zero-position photoelectric switch and the end-point photoelectric switch directly enters the main controller;

所述用户操控模块,用于实现操作人员对整个装置的控制,包括开机、启动;The user control module is used to realize the operator's control of the entire device, including booting and starting;

所述信息显示模块,用于根据应用需求显示运行过程中的相关数据信息;The information display module is used to display relevant data information in the running process according to application requirements;

基于上述系统控制器,装置上电进行初始化时,在主控制器控制下,通过步进电机控制器驱动梯形丝杆步进电机转动;当药推头端面与注射器推杆尾部安装的电涡流传感器被测物之间的距离达到指定范围后,电压比较器输出电平翻转,主控制器识别该电平状态变化,降低给药推头运动速度,以给药所需的速度V2推动注射器推杆;当终点光电开关输出电平发生翻转时,主控制器改变梯形丝杆步进电机运动方向,以速度V1向零位光电开关方向运动,最终停在零位。Based on the above system controller, when the device is powered on and initialized, under the control of the main controller, the stepper motor controller is used to drive the trapezoidal screw stepping motor to rotate; When the distance between the measured objects reaches the specified range, the output level of the voltage comparator is reversed, and the main controller recognizes the state change of the level, reduces the movement speed of the drug delivery pusher, and pushes the syringe pusher at the speed V2 required for drug delivery. ; When the output level of the photoelectric switch at the end point is reversed, the main controller changes the movement direction of the trapezoidal screw stepping motor, moves to the zero position photoelectric switch at the speed V1, and finally stops at the zero position.

进一步地,所述电压比较器的比较电压可依据微位移传感器探头端面与给药推头端面间的距离、微位移传感器灵敏度信息通过调节电位计设定,以实现给药推头端面与注射器推杆端面之间的距离达到指定范围后,电压比较器输出电平翻转。Further, the comparative voltage of the voltage comparator can be set by adjusting the potentiometer according to the distance between the end face of the micro-displacement sensor probe and the end face of the drug delivery pusher, and the sensitivity information of the micro-displacement sensor, so as to realize the push between the end face of the drug delivery pusher and the syringe pusher. When the distance between the rod end faces reaches the specified range, the voltage comparator output level flips.

进一步地,所述电机安装架上开有竖直方向长孔作为电机安装孔,梯形丝杆步进电机安装时,可通过竖直方向长孔微调梯形丝杆步进电机竖直方向的安装距离,以实现梯形丝杆与直线导轨相平行,则给药推头沿直线导轨运动时不会出现卡顿。Further, the motor mounting frame is provided with a vertical long hole as a motor mounting hole. When the trapezoidal screw stepping motor is installed, the vertical long hole can be used to fine-tune the installation distance of the trapezoidal screw stepping motor in the vertical direction. , so that the trapezoidal screw rod is parallel to the linear guide rail, so that no jamming occurs when the drug delivery pusher moves along the linear guide rail.

进一步地,所述微位移传感器探头安装在给药推头上部的安装孔内,通过可微调的锁紧装置固定,且所述微位移传感器探头端面与给药推头端面之间有一定距离。Further, the micro-displacement sensor probe is installed in the mounting hole on the upper part of the drug delivery pusher, and is fixed by a fine-tuning locking device, and there is a certain distance between the end face of the micro-displacement sensor probe and the end surface of the drug delivery pusher.

进一步地,该装置还包括安装在给药推头侧面的行程挡片,当行程挡片运动至零位光电开关或终点光电开关处时,零位光电开关和终点光电开关输出信号将发生变化,该信号传入主控制器,由此判别给药推头运动的起始位置和终止位置。Further, the device also includes a stroke block installed on the side of the drug delivery pusher. When the stroke block moves to the zero position photoelectric switch or the end point photoelectric switch, the output signals of the zero position photoelectric switch and the end point photoelectric switch will change, The signal is transmitted to the main controller, thereby judging the starting position and ending position of the dosing pusher movement.

本发明与现有技术相比,其显著优点为:Compared with the prior art, the present invention has the following significant advantages:

1)无需医护人员干预,可全自动完成给药。1) Dosing can be completed automatically without the intervention of medical staff.

2)本自动给药装置采用高精度非接触微位移传感器实时检测给药推头与注射器推杆之间的距离,保证系统快速启动。2) The automatic drug delivery device adopts a high-precision non-contact micro-displacement sensor to detect the distance between the drug delivery pusher and the syringe push rod in real time, so as to ensure the rapid start of the system.

3)可自主测量给药推头与注射器推杆之间相对位置信息,针对不同用药量,给药推头均可快速到达注射器推杆尾部并切换至给药速度,在满足及时用药的同时,保证用药安全。3) The relative position information between the dosing pusher and the syringe pusher can be measured independently. For different dosages, the dosing pusher can quickly reach the tail of the syringe pusher and switch to the drug delivery speed. Ensure medication safety.

下面结合附图对本发明作进一步详细描述。The present invention will be described in further detail below with reference to the accompanying drawings.

附图说明Description of drawings

图1是一个实施例中基于微位移传感器的自动给药装置机械结构图。FIG. 1 is a mechanical structure diagram of an automatic drug delivery device based on a micro-displacement sensor in one embodiment.

图2是一个实施例中给药推头驱动传动装置结构图。Fig. 2 is a structural diagram of a drug delivery pusher driving transmission device in an embodiment.

图3是一个实施例中给药推头内嵌微位移传感器探头安装结构图,其中图(a)为俯视图,图(b)为侧视图。Fig. 3 is a structural view of the installation structure of a probe with a micro-displacement sensor embedded in a drug delivery pusher according to an embodiment, wherein Fig. (a) is a top view and Fig. (b) is a side view.

图4是一个实施例中注射器推杆内嵌微位移传感器被测物结构图。FIG. 4 is a structural diagram of the object under test with a micro-displacement sensor embedded in the plunger of the syringe in one embodiment.

图5是一个实施例中注射器推杆胶接微位移传感器被测物结构图。FIG. 5 is a structural diagram of the object under test of the micro-displacement sensor glued to the syringe plunger in one embodiment.

图6是一个实施例中注射器推杆外套微位移传感器被测物结构图。Fig. 6 is a structural diagram of the measured object of the micro-displacement sensor of the sleeve of the syringe push rod in one embodiment.

图7是一个实施例中系统控制电路组成框图。FIG. 7 is a block diagram of a system control circuit in one embodiment.

图8是一个实施例中给药过程示意图,其中图(a)为以速度V1的给药过程示意,图(b)为以速度V2的给药过程示意。Fig. 8 is a schematic diagram of the administration process in an embodiment, wherein Fig. (a) is a schematic diagram of the administration process at a speed V1, and Fig. (b) is a schematic diagram of the administration process at a speed V2.

其中:1-基板;2-电机安装架;3-直线导轨;4-注射器安装架;5-终点光电开关安装座;6-零位光电开关安装座;7-直线导轨固定螺钉;8-注射器安装架固定螺钉;9-终点光电开关安装座固定螺钉;10-零位光电开关安装座固定螺钉;11-梯形丝杆步进电机;12-步进电机安装螺钉;13-梯形丝杆;14-梯形丝杆滑座;15-滚珠滑块;16-给药推头;17-零位光电开关;18-终点光电开关;19-行程挡片;20-行程挡片固定螺钉;21-长孔;22-微位移传感器探头;23-传感器探头固定螺钉;24-微位移传感器探头端面;25-给药推头端面;26-注射器;27-注射器推杆;28-内嵌式微位移传感器被测物;29-胶接式微位移传感器被测物;30-配件式微位移传感器被测物;31-竖直方向长孔。Among them: 1- base plate; 2- motor mounting frame; 3- linear guide rail; 4- syringe mounting frame; 5- end point photoelectric switch mounting seat; 6- zero position photoelectric switch mounting seat; 7- linear guide rail fixing screw; 8- syringe Mounting frame fixing screws; 9-Fixing screws for the end point photoelectric switch mounting seat; 10-Fixing screws for the zero position photoelectric switch mounting seat; 11- Trapezoidal screw stepping motor; 12-Stepping motor mounting screws; 13- Trapezoidal screw; 14 - Trapezoidal screw slide; 15- Ball slider; 16- Dosing pusher; 17- Zero position photoelectric switch; 18- End point photoelectric switch; 19- Stroke block; 20- Stroke block fixing screw; hole; 22-micro-displacement sensor probe; 23-sensor probe fixing screw; 24-micro-displacement sensor probe end face; 25-administration pusher end-face; 26-syringe; 27-syringe push rod; Measured object; 29- glued micro-displacement sensor measured object; 30- accessory micro-displacement sensor measured object; 31- vertical long hole.

具体实施方式Detailed ways

为了使本申请的目的、技术方案及优点更加清楚明白,以下结合附图及实施例,对本申请进行进一步详细说明。应当理解,此处描述的具体实施例仅仅用以解释本申请,并不用于限定本申请。In order to make the purpose, technical solutions and advantages of the present application more clearly understood, the present application will be described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application, but not to limit the present application.

需要说明,若本发明实施例中有涉及方向性指示(诸如上、下、左、右、前、后……),则该方向性指示仅用于解释在某一特定姿态(如附图所示)下各部件之间的相对位置关系、运动情况等,如果该特定姿态发生改变时,则该方向性指示也相应地随之改变。It should be noted that if there are directional indications (such as up, down, left, right, front, back, etc.) involved in the embodiments of the present invention, the directional indications are only used to explain a certain posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication also changes accordingly.

在一个实施例中,如图1所示,提供了一种基于微位移传感器的自动给药装置,包括基板1、电机安装架2、直线导轨3、注射器安装架4、终点光电开关安装座5、零位光电开关安装座6。电机安装架2、直线导轨3、注射器安装架4、终点光电开关安装座5和零位光电开关安装座6均固定在基板1上;注射器26固定在注射器安装架4上,注射器推杆27尾部装有电涡流传感器被测物;梯形丝杆步进电机11固定在电机安装架2上,直线导轨3上安装有滚珠滑块15,步进电机的梯形丝杆13上同轴装有梯形丝杆滑座14,滚珠滑块15和梯形丝杆滑座14均与给药推头16相连接;基板1上的终点光电开关安装座5和零位光电开关安装座6分别安装有终点光电开关18、零位光电开关17。电机安装架2为矩形,其底部开有螺纹孔,基板1对应位置开有通孔,在基板1背部通过固定螺钉将电机安装架2固定在基板1上;直线导轨3和注射器安装架4分别通过直线导轨固定螺钉7、注射器安装架固定螺钉8固定在基板1上;终点光电开关安装座5和零位光电开关安装座6分别通过终点光电开关安装座固定螺钉9、零位光电开关安装座固定螺钉10固定在基板1上。In one embodiment, as shown in FIG. 1 , an automatic drug delivery device based on a micro-displacement sensor is provided, which includes a substrate 1 , a motor mount 2 , a linear guide 3 , a syringe mount 4 , and a terminal photoelectric switch mount 5 , Zero photoelectric switch mounting seat 6. Motor mount 2, linear guide 3, syringe mount 4, end-point photoelectric switch mount 5 and zero-position photoelectric switch mount 6 are all fixed on the base plate 1; the syringe 26 is fixed on the syringe mount 4, and the tail of the syringe push rod 27 The eddy current sensor is equipped with the measured object; the trapezoidal screw stepping motor 11 is fixed on the motor mounting frame 2, the linear guide 3 is installed with a ball slider 15, and the trapezoidal screw 13 of the stepping motor is coaxially equipped with a trapezoidal wire The rod sliding seat 14, the ball sliding block 15 and the trapezoidal screw sliding seat 14 are all connected with the dosing pusher 16; the end point photoelectric switch mounting seat 5 and the zero position photoelectric switch mounting seat 6 on the base plate 1 are respectively installed with end point photoelectric switches 18. Zero photoelectric switch 17. The motor mounting frame 2 is rectangular, with threaded holes at the bottom and through holes at the corresponding positions of the base plate 1. The motor mounting frame 2 is fixed on the base plate 1 by fixing screws on the back of the base plate 1; the linear guide rail 3 and the syringe mounting frame 4 are respectively It is fixed on the base plate 1 by the fixing screw 7 of the linear guide and the fixing screw 8 of the syringe mounting frame; the end point photoelectric switch mounting seat 5 and the zero position photoelectric switch mounting seat 6 are respectively fixed by the end point photoelectric switch mounting seat fixing screw 9 and the zero position photoelectric switch mounting seat. The fixing screws 10 are fixed on the base plate 1 .

如图2所示,梯形丝杆步进电机11通过步进电机安装螺钉12固定在电机安装架2上。步进电机的梯形丝杆13上同轴装有梯形丝杆滑座14,直线导轨3上安装有滚珠滑块15。滚珠滑块15上通过螺钉固定有给药推头16,梯形丝杆滑座14通过螺钉固定在给药推头16上。梯形丝杆步进电机11旋转时带动梯形丝杆13一起转动,从而通过梯形丝杆滑座14带动给药推头16一起沿直线导轨3做往复运动。As shown in FIG. 2 , the trapezoidal screw stepping motor 11 is fixed on the motor mounting frame 2 through the stepping motor mounting screws 12 . The trapezoidal screw 13 of the stepping motor is coaxially provided with a trapezoidal screw sliding seat 14 , and the linear guide 3 is provided with a ball sliding block 15 . The ball slider 15 is fixed on the drug delivery pusher 16 by screws, and the trapezoidal screw slide 14 is fixed on the drug delivery pusher 16 by screws. When the trapezoidal screw stepping motor 11 rotates, it drives the trapezoidal screw 13 to rotate together, thereby driving the drug delivery pusher 16 to reciprocate along the linear guide rail 3 through the trapezoidal screw sliding seat 14 .

如图1、图2所示,本实施例所述零位光电开关17和终点光电开关18分别固定在零位光电开关安装座6和终点光电开关安装座5上,行程挡片19通过行程挡片固定螺钉20安装在给药推头16侧面,当行程挡片19运动至零位光电开关17或终点光电开关18处时,零位光电开关17和终点光电开关18输出信号将发生翻转,该信号送入主控制器,使其用于判别给药推头16运动的起始位置和终止位置。终点光电开关安装座5下表面固定孔为长孔21,方便微调终点光电开关安装座5的位置,在整体调试时确定最终完成给药的位置。As shown in FIGS. 1 and 2 , the zero-position photoelectric switch 17 and the end-point photoelectric switch 18 in this embodiment are respectively fixed on the zero-position photoelectric switch mounting seat 6 and the end-point photoelectric switch mounting seat 5 , and the travel stopper 19 passes through the travel stopper. The plate fixing screw 20 is installed on the side of the drug delivery pusher 16. When the stroke block 19 moves to the zero position photoelectric switch 17 or the end photoelectric switch 18, the output signal of the zero position photoelectric switch 17 and the end photoelectric switch 18 will be reversed, the The signal is sent to the main controller, which is used to determine the starting position and the ending position of the movement of the drug delivery pusher 16 . The fixing hole on the lower surface of the photoelectric switch mounting seat 5 at the end point is a long hole 21, which is convenient for fine-tuning the position of the photoelectric switch mounting seat 5 at the end point, and determines the position where the drug is finally completed during the overall debugging.

如图3、图4所示,本实施例所述微位移传感器探头22安装在给药推头16上部的安装孔内,使用传感器探头固定螺钉23或类似的可微调的锁紧装置固定。安装过程中应保证微位移传感器探头端面24距离给药推头端面25有一定距离,避免给药过程中微位移传感器探头端面24直接与注射器推杆27尾部直接接触,造成微位移传感器探头22损坏。为避免给药推头16材料对测量产生影响,给药推头16材料可选用PEEK、PTFE、亚克力等非金属材料。As shown in FIGS. 3 and 4 , the micro-displacement sensor probe 22 in this embodiment is installed in the mounting hole on the upper part of the drug delivery pusher 16 , and is fixed by the sensor probe fixing screw 23 or a similar fine-tuning locking device. During the installation process, it should be ensured that the end face 24 of the micro-displacement sensor probe is at a certain distance from the end face 25 of the drug delivery pusher, so as to avoid the direct contact between the end face 24 of the micro-displacement sensor probe and the tail of the syringe push rod 27 during the drug delivery process, resulting in damage to the micro-displacement sensor probe 22. . In order to avoid the influence of the material of the drug delivery pusher 16 on the measurement, the material of the drug delivery pusher 16 can be selected from non-metallic materials such as PEEK, PTFE, and acrylic.

如图4、图5、图6所示,本实施例所述注射器26固定在注射器安装架4上,注射器推杆27尾部以内嵌28、胶接29或配件30等形式装有电涡流传感器被测物,材料根据实际应用可选择铝合金、钛合金等。As shown in Fig. 4, Fig. 5, Fig. 6, the syringe 26 in this embodiment is fixed on the syringe mounting frame 4, and the tail of the syringe push rod 27 is equipped with an eddy current sensor in the form of inlay 28, glue 29 or accessories 30, etc. According to the actual application, the material can be selected from aluminum alloy, titanium alloy, etc.

如图7所示,本实施例所述基于微位移传感器的自动给药装置,还包括系统控制器。系统控制器包含主控制器、用户控制模块、信息显示模块、步进电机驱动器、微位移传感器处理板、电压比较器及电位计。主控制器通过控制步进电机驱动器带动梯形丝杆步进电机11做旋转运动;微位移传感器探头22与微位移传感器处理板相连接,微位移传感器处理板输出的模拟信号经电压比较器转换成数字电平后进入主控制器,电压比较器的比较电压可由电位计进行调节;零位光电开关17和终点光电开关18输出的数字信号直接进入主控制器;用户控制模块用于操作人员对整个装置的控制,包括开机、启动等功能;信息显示模块则根据应用需求显示运行过程中的相关信息。As shown in FIG. 7 , the micro-displacement sensor-based automatic drug delivery device according to this embodiment further includes a system controller. The system controller includes the main controller, user control module, information display module, stepper motor driver, micro-displacement sensor processing board, voltage comparator and potentiometer. The main controller drives the trapezoidal screw stepping motor 11 to rotate by controlling the stepping motor driver; the micro-displacement sensor probe 22 is connected with the micro-displacement sensor processing board, and the analog signal output by the micro-displacement sensor processing board is converted into a voltage comparator. After the digital level enters the main controller, the comparison voltage of the voltage comparator can be adjusted by the potentiometer; the digital signals output by the zero-position photoelectric switch 17 and the end-point photoelectric switch 18 directly enter the main controller; the user control module is used by the operator to The control of the device includes functions such as power-on and startup; the information display module displays the relevant information during the operation according to the application requirements.

如图8所示,本实施例所述基于微位移传感器的自动给药装置,在系统启动时,若给药推头16尚未与注射器推杆27接触,此时给药推头16的运行速度为V1;当给药推头16运行至与注射器推杆27接触后,系统调整给药推头16的运行速度至所需给药速度V2。通常情况下,V1>>V2,提高装置工作效率。As shown in FIG. 8 , in the automatic drug delivery device based on the micro-displacement sensor described in this embodiment, when the system starts, if the drug delivery pusher 16 has not been in contact with the syringe pusher 27, the running speed of the drug delivery pusher 16 at this time is V1; when the drug delivery pusher 16 runs to contact with the syringe plunger 27, the system adjusts the running speed of the drug delivery pusher 16 to the required drug delivery speed V2. Normally, V1>>V2, which improves the working efficiency of the device.

本实施例基于微位移传感器的自动给药装置的工作原理:在装置安装时,需调整终点光电开关安装座5,以确保当注射器推杆27达到注射器26底部时,终点光电开关18输出电平发生翻转。系统上电后,在主控制器控制下,通过步进电机控制器驱动梯形丝杆步进电机11转动,进而通过梯形丝杆滑座14带动给药推头16一起沿直线导轨3朝零位光电开关17方向运动。当给药推头16运动至零位时,给药推头16上固定的行程挡片19将遮蔽零位光电开关17的收发光路,主控制器将会识别零位光电开关17输出电平发生翻转,并停止梯形丝杆步进电机11转动,使得给药推头16停止在零位。当操作人员按下启动按键后,梯形丝杆步进电机11带动给药推头16较快速度V1向注射器推杆27方向移动。安装在给药推头16内部的微位移传感器探头22实时探测其与注射器推杆27尾部安装的电涡流传感器被测物之间的距离,微位移传感器处理板将该距离信息转化成电压信号送入电压比较器。电压比较器的比较电压可依据微位移传感器探头端面24与给药推头端面25间的距离、微位移传感器灵敏度等信息通过调节电位计设定,以保证给药推头端面25与注射器推杆端面之间的距离达到指定范围后,比较器输出电平翻转。主控制器识别该电平状态变化,降低给药推头运动速度,以给药所需的速度V2推动注射器推杆。当终点光电开关18输出电平发生翻转时,主控制器改变梯形丝杆步进电机11运动方向,以较快速度V1向零位光电开关17方向运动,最终停在零位,系统完成一次自动给药。整个运行过程中的相关信息由信息显示模块显示。The working principle of the automatic drug delivery device based on the micro-displacement sensor in this embodiment: when the device is installed, the end point photoelectric switch mounting seat 5 needs to be adjusted to ensure that when the syringe push rod 27 reaches the bottom of the syringe 26, the end point photoelectric switch 18 outputs the level Flip occurs. After the system is powered on, under the control of the main controller, the stepping motor controller drives the trapezoidal screw stepping motor 11 to rotate, and then drives the drug delivery pusher 16 along the linear guide 3 to the zero position through the trapezoidal screw sliding seat 14. The photoelectric switch 17 moves in the direction. When the dosing pusher 16 moves to the zero position, the fixed travel stopper 19 on the dosing pusher 16 will shield the light-receiving light path of the zero-position photoelectric switch 17, and the main controller will recognize that the output level of the zero-position photoelectric switch 17 occurs. Turn over, and stop the rotation of the trapezoidal screw stepping motor 11, so that the drug delivery pusher 16 stops at the zero position. When the operator presses the start button, the trapezoidal screw stepping motor 11 drives the drug delivery pusher 16 to move toward the syringe push rod 27 at a relatively high speed V1. The micro-displacement sensor probe 22 installed inside the drug delivery pusher 16 detects the distance between it and the eddy-current sensor measured object installed at the tail of the syringe pusher 27 in real time, and the micro-displacement sensor processing board converts the distance information into a voltage signal for transmission. into the voltage comparator. The comparison voltage of the voltage comparator can be set by adjusting the potentiometer according to the distance between the probe end face 24 of the micro-displacement sensor and the end face 25 of the drug delivery pusher, the sensitivity of the micro-displacement sensor, etc. When the distance between the end faces reaches the specified range, the output level of the comparator is inverted. The main controller recognizes the state change of the level, reduces the movement speed of the drug delivery pusher, and pushes the syringe pusher at the speed V2 required for drug delivery. When the output level of the photoelectric switch 18 at the end point is reversed, the main controller changes the movement direction of the trapezoidal screw stepping motor 11, moves to the zero position photoelectric switch 17 at a relatively fast speed V1, and finally stops at the zero position, and the system completes an automatic Dosing. The relevant information in the whole running process is displayed by the information display module.

本发明自动给药装置采用高精度非接触微位移传感器实时检测给药推头与注射器推杆之间的距离,保证系统快速启动。在给药推头与注射器推杆之间距离达到数微米范围内时,改变给药推头速度至设定给药速度,在满足及时用药的同时,严格控制给药速度,保证用药安全。The automatic drug delivery device of the present invention adopts a high-precision non-contact micro-displacement sensor to detect the distance between the drug delivery pusher and the syringe push rod in real time, so as to ensure the rapid start of the system. When the distance between the dosing pusher and the syringe pusher is within a few microns, change the speed of the dosing pusher to the set dosing speed, and strictly control the dosing speed to ensure the safety of medication while satisfying the timely medication.

上述实施例仅仅是为清楚地说明所作的举例,而非对实施方式的限定。对于所属领域的普通技术人员来说,在上述说明的基础上还可以做出其他不同形式的变化或变动。这里无需也无法对所有实施方式予以穷举。而由此所引申出的显而易见的变化或变动仍处于本发明创造的保护范围之中。The above-mentioned embodiments are only examples for clear description, and are not intended to limit the embodiments. For those of ordinary skill in the art, changes or modifications in other different forms can also be made on the basis of the above description. There is no need and cannot be exhaustive of all implementations here. And the obvious changes or changes derived from this are still within the protection scope of the present invention.

Claims (10)

1. An automatic drug delivery device based on a micro-displacement sensor is characterized by comprising a base plate (1), and a motor mounting rack (2), a linear guide rail (3), an injector mounting rack (4), a terminal photoelectric switch mounting seat (5) and a zero photoelectric switch mounting seat (6) which are fixed on the base plate (1); an injector (26) is fixed on the injector mounting rack (4), and a measured object of the eddy current sensor is mounted at the tail part of an injector push rod (27); a trapezoidal screw stepping motor (11) is fixedly installed on the motor installation frame (2), a ball sliding block (15) is installed on the linear guide rail (3), a trapezoidal screw sliding seat (14) is coaxially installed on a trapezoidal screw (13) of the stepping motor, and the ball sliding block (15) and the trapezoidal screw sliding seat (14) are both connected with a drug delivery push head (16); the zero photoelectric switch mounting seat (6) and the terminal photoelectric switch mounting seat (5) are sequentially arranged along the direction of pushing and injecting the medicine by the injector push rod (27), and a zero photoelectric switch (17) and a terminal photoelectric switch (18) are respectively mounted on the zero photoelectric switch mounting seat and the terminal photoelectric switch mounting seat;
the device is initialized after being electrified, the trapezoidal screw stepping motor (11) is driven to rotate, the medicine feeding push head (16) is driven to move towards the direction of the zero photoelectric switch (17) along the linear guide rail (3) through the trapezoidal screw sliding seat (14) and the ball sliding block (15), and the device is initialized when the medicine feeding push head (16) moves to the zero photoelectric switch (17); when the automatic dosing device is started to work, the trapezoidal lead screw stepping motor (11) drives the dosing push head (16) to move towards the direction of the injector push rod (27) at a speed V1, a micro-displacement sensor probe (22) arranged in the dosing push head (16) detects the distance between the end face (25) of the dosing push head and a measured object of an eddy current sensor arranged at the tail part of the injector push rod (27) in real time, namely the distance between the end face (25) of the dosing push head and the end face of the injector push rod, and when the distance reaches a specified range, the dosing push head (16) continues to push the injector push rod (27) at a speed V2 required by dosing; when the output level of the end-point photoelectric switch (18) is turned over, the movement direction of the trapezoidal lead screw stepping motor (11) is changed, the trapezoidal lead screw stepping motor moves towards the zero-position photoelectric switch (17) at a speed V1, and finally stops at the zero position, so that the device finishes one-time automatic dosing; wherein V1> > V2.
2. The automatic drug delivery device based on the micro-displacement sensor, which is characterized in that the device further comprises a system controller, wherein the system controller comprises a main controller, a user control module, an information display module, a stepping motor driver, a micro-displacement sensor processing board, a voltage comparator and a potentiometer;
the main controller drives the trapezoidal screw rod stepping motor (11) to rotate by controlling a stepping motor driver;
the micro-displacement sensor probe (22) is connected with the micro-displacement sensor processing board, an analog signal output by the micro-displacement sensor processing board is converted into a digital level through a voltage comparator and then enters a main controller, and the comparison voltage of the voltage comparator is adjusted by a potentiometer;
digital signals output by the zero photoelectric switch (17) and the terminal photoelectric switch (18) directly enter the main controller;
the user control module is used for realizing the control of an operator on the whole device, including starting and starting;
the information display module is used for displaying related data information in the running process according to application requirements;
based on the system controller, when the device is electrified and initialized, the stepping motor controller drives the trapezoidal screw stepping motor (11) to rotate under the control of the main controller; when the distance between the end face (25) of the medicine push head and a measured object of an eddy current sensor arranged at the tail part of the push rod (27) of the injector reaches a specified range, the output level of the voltage comparator is reversed, the main controller identifies the state change of the level, the movement speed of the medicine administration push head (16) is reduced, and the push rod (27) of the injector is pushed at the speed V2 required by medicine administration; when the output level of the end photoelectric switch (18) is turned over, the main controller changes the movement direction of the trapezoidal lead screw stepping motor (11), moves towards the direction of the zero photoelectric switch (17) at a speed V1, and finally stops at the zero position.
3. The automatic drug delivery device based on the micro-displacement sensor as claimed in claim 2, wherein the comparison voltage of the voltage comparator can be set by adjusting a potentiometer according to the distance between the probe end face (24) of the micro-displacement sensor and the drug delivery pusher end face (25) and the sensitivity information of the micro-displacement sensor, so that the output level of the voltage comparator is inverted after the distance between the drug delivery pusher end face (25) and the syringe push rod end face reaches a specified range.
4. The automatic drug delivery device based on the micro-displacement sensor according to claim 1, wherein the motor mounting rack (2) is provided with a vertical slot (31) as a motor mounting hole, and when the trapezoidal lead screw stepping motor (11) is mounted, the mounting distance of the trapezoidal lead screw stepping motor (11) in the vertical direction can be finely adjusted through the vertical slot (31) so as to realize that the trapezoidal lead screw (13) is parallel to the linear guide rail (3), and the drug delivery pushing head (16) cannot be jammed when moving along the linear guide rail (3).
5. The automatic drug delivery device based on the micro-displacement sensor is characterized in that the micro-displacement sensor probe (22) is installed in a mounting hole at the upper part of the drug delivery push head (16) and is fixed by a locking device capable of being adjusted finely, and a certain distance is reserved between the end surface (24) of the micro-displacement sensor probe and the end surface (25) of the drug delivery push head.
6. The automatic drug delivery device based on the micro-displacement sensor is characterized in that the device further comprises a stroke blocking piece (19) arranged on the side surface of the drug delivery pushing head (16), when the stroke blocking piece (19) moves to the zero photoelectric switch (17) or the end photoelectric switch (18), the output signals of the zero photoelectric switch (17) and the end photoelectric switch (18) are changed, and the signals are transmitted to the main controller, so that the starting position and the ending position of the motion of the drug delivery pushing head (16) are judged.
7. The micro-displacement sensor based automatic drug delivery device according to claim 1, characterized in that the eddy current sensor is mounted at the tail of the syringe push rod (27) in an embedded manner, glued or fitted manner.
8. The micro-displacement sensor-based automatic drug delivery device according to claim 1, characterized in that the fixing hole between the end-point photoelectric switch mounting seat (5) and the base plate (1) is a long hole, the position of the end-point photoelectric switch mounting seat (5) can be finely adjusted through the hole, and the final drug delivery position is determined during the whole debugging process.
9. The micro-displacement sensor-based automatic drug delivery device as claimed in claim 1, wherein the material of the drug delivery push head (16) is PEEK or PTFE or acrylic non-metallic material.
10. The automatic drug delivery device based on the micro-displacement sensor as claimed in claim 1, wherein the material of the object to be tested of the eddy current sensor is selected from aluminum alloy or titanium alloy.
CN202210198776.3A 2022-03-01 2022-03-01 An automatic drug delivery device based on micro-displacement sensor Active CN114632217B (en)

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