CN114601599A - Freely-deformable absorbable metal filling net and preparation method thereof - Google Patents
Freely-deformable absorbable metal filling net and preparation method thereof Download PDFInfo
- Publication number
- CN114601599A CN114601599A CN202210194108.3A CN202210194108A CN114601599A CN 114601599 A CN114601599 A CN 114601599A CN 202210194108 A CN202210194108 A CN 202210194108A CN 114601599 A CN114601599 A CN 114601599A
- Authority
- CN
- China
- Prior art keywords
- absorbable
- filling net
- net
- basic
- freely deformable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229910052751 metal Inorganic materials 0.000 title claims abstract description 48
- 239000002184 metal Substances 0.000 title claims abstract description 48
- 238000002360 preparation method Methods 0.000 title abstract description 10
- 238000005452 bending Methods 0.000 claims abstract description 8
- 238000000034 method Methods 0.000 claims description 8
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 6
- 239000011248 coating agent Substances 0.000 claims description 5
- 238000000576 coating method Methods 0.000 claims description 5
- 229920000954 Polyglycolide Polymers 0.000 claims description 3
- 230000001788 irregular Effects 0.000 claims description 3
- ORUIBWPALBXDOA-UHFFFAOYSA-L magnesium fluoride Chemical compound [F-].[F-].[Mg+2] ORUIBWPALBXDOA-UHFFFAOYSA-L 0.000 claims description 3
- 229910001635 magnesium fluoride Inorganic materials 0.000 claims description 3
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims description 3
- 235000019341 magnesium sulphate Nutrition 0.000 claims description 3
- 229920002463 poly(p-dioxanone) polymer Polymers 0.000 claims description 3
- 239000000622 polydioxanone Substances 0.000 claims description 3
- 239000004633 polyglycolic acid Substances 0.000 claims description 3
- 239000012528 membrane Substances 0.000 claims 3
- 238000005485 electric heating Methods 0.000 claims 1
- 230000017423 tissue regeneration Effects 0.000 abstract description 5
- 230000000694 effects Effects 0.000 abstract description 2
- 210000001519 tissue Anatomy 0.000 description 13
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 4
- 230000015556 catabolic process Effects 0.000 description 4
- 238000006731 degradation reaction Methods 0.000 description 4
- 230000006378 damage Effects 0.000 description 3
- 239000010410 layer Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000000178 monomer Substances 0.000 description 2
- -1 polypropylene Polymers 0.000 description 2
- 239000002356 single layer Substances 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 description 1
- 229910000640 Fe alloy Inorganic materials 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 229910000861 Mg alloy Inorganic materials 0.000 description 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 229920004933 Terylene® Polymers 0.000 description 1
- 206010048038 Wound infection Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 229910001297 Zn alloy Inorganic materials 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 238000010923 batch production Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 201000004101 esophageal cancer Diseases 0.000 description 1
- 238000007731 hot pressing Methods 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 210000004224 pleura Anatomy 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Prostheses (AREA)
Abstract
The application relates to a freely deformable absorbable metal filling net and a preparation method thereof, and relates to the field of biological patches. The preparation method of the metal filling net comprises the following steps: extruding the metal cast ingot to prepare a wire; bending the wire rod and leaving an opening to form a basic body; connecting a plurality of basic bodies through openings to form a rudiment filling net; and closing the opening of the basic body to form a finished filling net. The metal filling net has the effects of fitting movement along with the human tissue repair surface and reducing the possibility of damaging the human quality repair surface. The preparation method of the metal filling net has the advantages of being simple to operate and capable of producing the filling net in batches.
Description
Technical Field
The application relates to the field of biological patches, in particular to a freely deformable absorbable metal filling net and a preparation method thereof.
Background
The filling net, also called biological patch, can be regarded as 'cell scaffold' and is prepared by a series of advanced technologies such as cross-linking fixation, multi-azimuth antigen removal and the like, can play a good role of scaffold after being implanted into a human body according to regenerative medicine principle, biological principle and immunological principle, fills up the missing tissue of the damaged part, can promote the self-repair function of the human body to gradually grow new tissue in the original position, replaces biological material and completes the regeneration of organ tissue. The filling net is mainly applied to neurosurgery, repair of endocranium, repair after esophageal cancer excision, repair of pleura, repair of skull and the like in the medical field.
The preparation materials of the filling net mainly comprise polypropylene, polytetrafluoroethylene, polyester, terylene and the like, and the materials have the problem that the materials cannot be absorbed by a human body or are partially absorbed by the human body, so that the probability of injury caused by wound infection or the need of secondary operation for taking out is increased. Therefore, a filling net prepared by using degradable metal has been developed at present, and the specific method is that degradable metal filaments are obtained by extruding and drawing a degradable metal cast ingot, the degradable metal filaments are cut and uniformly mixed after being processed, then the degradable metal filaments are pressed to be made into metal sheet monomers, through holes are formed in the metal sheet monomers, degradable metal powder is added into the through holes, then, a degradable metal original sheet is formed by hot pressing, and the degradable metal original sheet is cleaned and sterilized to obtain the degradable metal patch.
The problem that the filling net cannot be absorbed by a human body or partially absorbed by the human body is well solved by the degradable metal patch developed at present, but the problem that the degradable metal patch has the defect of high bending strength and cannot be attached to the human tissue repairing surface to move along with the human tissue repairing surface is solved, and the condition that the human tissue repairing surface is damaged is caused. Therefore, how to solve the above disadvantages of the degradable metal patch has become an urgent problem to be solved.
Disclosure of Invention
In order to solve the problems of large bending strength and sharp edges of a metal patch, the application provides an absorbable metal filling net capable of deforming freely and a preparation method thereof.
First aspect, this application provides can freely warp can absorb metal and fill up net, adopts following technical scheme:
the freely deformable absorbable metal filling net is composed of a plurality of basic bodies, each basic body comprises a frame and through holes located in the frame, the basic bodies are connected in a mode that the frames penetrate through the through holes of the adjacent frames, and relative movement can occur between the adjacent basic bodies.
By adopting the technical scheme, the filling net is formed by connecting the plurality of basic bodies, and the filling net is endowed with deformable performance by utilizing the relative motion between the adjacent basic bodies, so that the filling net can move along with the human tissue repairing surface in a fitting manner, the possibility that the filling net damages the human tissue repairing surface is reduced, and the repair of the human tissue is facilitated.
In a specific embodiment, the surface of the frame is an arc-shaped surface.
By adopting the technical scheme, the possibility that the filling net can scratch the human tissue repairing surface in the process that the filling net moves along with the human tissue repairing surface can be reduced.
In a specific embodiment, the inner side wall of the through hole is circular or polygonal.
In a specific embodiment, the shape of the frame is circular or polygonal.
Through adopting above-mentioned technical scheme for can take place relative motion between the adjacent basic body.
In a specific possible embodiment, several of said basic bodies have the same or different specifications.
By adopting the technical scheme, the specification of the basic body can be selected according to actual requirements.
In a specific possible embodiment, several of said elementary bodies are arranged in a regular or irregular shape.
By adopting the technical scheme, the filling net can be made into different shapes according to actual requirements.
In a particular embodiment, the base body is coated with a magnesium fluoride or magnesium sulfate coating.
By adopting the technical scheme, the degradation rate of the filling net can be reduced, so that the filling net can keep a complete form in a specified degradation period.
In a specific embodiment, the base body is coated with a polyglycolic acid absorbable film, a polydioxanone absorbable film or a polylactic glycolic acid absorbable film.
By adopting the technical scheme, the biocompatibility of the filling net can be enhanced, and the occurrence of rejection reaction is reduced.
In a specific possible embodiment, several of said bases form one layer or are stacked in multiple layers.
By adopting the technical scheme, the filling net can be made into different thicknesses according to actual requirements.
In a second aspect, the application provides a method for preparing an absorbable metal filling net capable of freely deforming, which adopts the following technical scheme:
the preparation method of the freely deformable absorbable metal filling net comprises the following steps:
extruding the metal cast ingot to prepare a wire;
bending the wire rod and leaving an opening to form a basic body;
connecting a plurality of basic bodies through openings to form a rudiment filling net;
and closing the opening of the basic body to form a finished filling net.
By adopting the technical scheme, the filling net is manufactured, the operation is simple, and the batch production can be realized.
In summary, the present application includes at least one of the following beneficial technical effects:
1. according to the filling net, the plurality of basic bodies are connected in a perforation mode, so that the adjacent basic bodies can move relatively, the filling net is endowed with the deformable performance, the bending strength of the filling net is reduced, and the filling net can move in a fitting mode along with the human tissue repair surface;
2. this application sets up the surface of frame into the arcwall face to reduce the sharpness of frame edge, thereby can reduce the possibility of filling net fish tail human tissue restoration face.
Drawings
Fig. 1 is a schematic structural view of the freely deformable absorbable metal shim net in example 1.
Fig. 2 is a schematic structural view of the freely deformable absorbable metal shim net in example 2.
Fig. 3 is a schematic structural view of the freely deformable absorbable metal shim net in example 3.
Fig. 4 is a schematic structural view of the freely deformable absorbable metal shim net in example 4.
Description of reference numerals: 1. a base body; 11. a frame; 12. and a through hole.
Detailed Description
The present application is described in further detail below with reference to figures 1-4.
The embodiment of the application discloses an absorbable metal filling net capable of deforming freely.
Example 1
Referring to fig. 1, the freely deformable absorbable metal filling net is formed by staggering a plurality of basic bodies 1 with the same specification, each basic body 1 comprises a frame 11 and through holes 12 positioned in the frame 11, and the basic bodies 1 are connected in a mode that the frames 11 penetrate through the through holes 12, so that relative movement can be generated between the basic bodies 1, the formed filling net can deform to a certain degree, and the filling net can move along with the fit of a human tissue repair surface in actual application.
The frame 11 is circular and the surface of the frame 11 is smooth, so that the possibility that the frame 11 can scratch the human tissue repair surface in the moving process of the filling net is reduced. The inner side wall of the through-hole 12 is also circular to facilitate smooth relative movement between the base bodies 1. In other embodiments, the frame 11 may be polygonal, such as triangular, quadrilateral, pentagonal, etc., and when the frame 11 is polygonal, the surface of the frame 11 is an arc surface, so as to reduce the damage of the frame 11 to the repair surface of the human tissue. The inner side wall of the through hole 12 may also be polygonal, and the inner side walls of the frame 11 and the through hole 12 may be set to a specific shape according to actual requirements, so that the purpose of relative movement between the base bodies 1 can be achieved.
In order to meet the actual requirement, a plurality of basic bodies 1 are arranged in a regular shape in a row and a column mode, and a filling net formed by the plurality of basic bodies 1 is a single layer.
The basic body 1 is made of pure magnesium, but in other embodiments, other kinds of metal materials that can be absorbed by the human body, such as magnesium alloy, pure iron, iron alloy, pure zinc or zinc alloy, can be selected. In order to reduce the degradation rate of the filling net and enable the filling net to keep an intact shape in a specific degradation period so as to improve the safety, a magnesium fluoride coating or a magnesium sulfate coating is attached to the surface of the basic body 1.
The implementation principle of the embodiment 1 is as follows: the plurality of basic bodies 1 are connected in a staggered mode according to the mode that the frame 11 penetrates through the through hole 12, so that the basic bodies 1 can move relatively, the formed filling net has the deformation capacity, the bending strength of the filling net is reduced, and the filling net can move along with the fit of the human tissue repair surface.
Example 2
Referring to fig. 2, the present embodiment is different from embodiment 1 in that the plurality of basic bodies 1 include square basic bodies 1 and circular basic bodies 1, and the plurality of basic bodies 1 are stacked into two layers, so that the formed padding net has a certain thickness, and the padding net can better adapt to actual requirements. In other embodiments, several base bodies 1 may also be stacked in three or four layers, etc.
In order to provide the formed filling net with better stability and mechanical property, the square basic bodies 1 are connected with each other through the two circular basic bodies 1 in a specific direction.
In order to improve the biocompatibility of the filling net and reduce the rejection reaction of the filling net, the surface of the basic body 1 is coated with a polyglycolic acid absorbable film, a polydioxanone absorbable film or a polylactic glycolic acid absorbable film. Meanwhile, the absorbable film can improve the overall mechanical property of the filling net to a certain extent.
Example 3
Referring to fig. 3, the difference between this embodiment and embodiment 1 is that a plurality of basic bodies 1 have two different sizes and are arranged in a regular shape, so that the formed shimming net can be adapted to actual requirements.
Example 4
Referring to fig. 4, the present embodiment is different from embodiment 1 in that a plurality of basic bodies 1 having two sizes are arranged in an irregular shape so that the formed shimming net can be adapted to actual needs.
The embodiment of the application also discloses a preparation method of the freely deformable absorbable metal filling net, which specifically comprises the following steps:
putting the metal cast ingot into an extruder, and extruding a wire;
bending and cutting the wire rod by using a die to form a basic body 1 with an opening;
connecting a plurality of basic bodies 1 in a staggered manner by passing through the through holes 12 through the openings to form a rudiment filling net;
and adhering the openings of the basic body 1 in the rudiment filling net by using a dispensing process so as to form a finished product filling net.
In other embodiments, the single-layer finished shim net may be stacked into multiple layers to form shim nets of different thicknesses, and then the openings of the base body 1 may be adhered by using a dispensing process.
The above embodiments are preferred embodiments of the present application, and the protection scope of the present application is not limited by the above embodiments, so: all equivalent changes made according to the structure, shape and principle of the present application shall be covered by the protection scope of the present application.
Claims (10)
1. But freely warp can absorb metal and fill up net, its characterized in that: the novel multifunctional electric heating element is characterized by comprising a plurality of basic bodies (1), wherein each basic body (1) comprises a frame (11) and a through hole (12) located in the frame (11), the basic bodies (1) are connected in a mode that the frames (11) penetrate through the through holes (12) of the adjacent frames (11), and relative movement can occur between the adjacent basic bodies (1).
2. The freely deformable absorbable metal mesh padding of claim 1, wherein: the surface of the frame (11) is an arc-shaped surface.
3. The freely deformable absorbable metal patch mesh of claim 1, wherein: the inner side wall of the through hole (12) is circular or polygonal.
4. The freely deformable absorbable metal patch mesh of claim 1, wherein: the shape of the frame (11) is circular or polygonal.
5. The freely deformable absorbable metal patch mesh of claim 1, wherein: the specifications of a plurality of the basic bodies (1) are the same or different.
6. The freely deformable absorbable metal patch mesh of claim 1, wherein: a plurality of the basic bodies (1) are arranged in a regular or irregular shape.
7. The freely deformable absorbable metal patch mesh of claim 1, wherein: the basic body (1) is coated with a magnesium fluoride coating or a magnesium sulfate coating.
8. The freely deformable absorbable metal patch mesh of claim 1, wherein: the basic body (1) is coated with a polyglycolic acid absorbable membrane, a polydioxanone absorbable membrane or a polylactic-co-glycolic acid absorbable membrane.
9. The freely deformable absorbable metal mesh padding of claim 1, wherein: several of the basic bodies (1) are formed into one layer or stacked into a plurality of layers.
10. The method for preparing a freely deformable absorbable metal mesh padding according to any one of claims 1 to 9, wherein: the method comprises the following steps:
extruding the metal cast ingot to prepare a wire;
bending the wire rod and leaving an opening to form a basic body (1);
connecting a plurality of basic bodies (1) through openings to form a rudiment filling net;
the opening of the basic body (1) is closed to form a finished filling net.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210194108.3A CN114601599A (en) | 2022-03-01 | 2022-03-01 | Freely-deformable absorbable metal filling net and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210194108.3A CN114601599A (en) | 2022-03-01 | 2022-03-01 | Freely-deformable absorbable metal filling net and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114601599A true CN114601599A (en) | 2022-06-10 |
Family
ID=81861734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210194108.3A Pending CN114601599A (en) | 2022-03-01 | 2022-03-01 | Freely-deformable absorbable metal filling net and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114601599A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH168207A (en) * | 1933-02-06 | 1934-03-31 | Sebald Albert | Metal link net. |
| CN105188600A (en) * | 2013-03-11 | 2015-12-23 | 伊西康公司 | Single plane tissue repair patch |
| US20180271572A1 (en) * | 2017-03-27 | 2018-09-27 | Sunnybrook Research Institute | Miniature or micro-scale conformable chain mail device for orthopaedic fixation, stabilization, and repair |
| CN111840648A (en) * | 2016-12-28 | 2020-10-30 | 广州迈普再生医学科技股份有限公司 | Multilayer composite tissue repair patch and preparation method thereof |
| US20210178114A1 (en) * | 2019-12-13 | 2021-06-17 | Charles Joseph Brumlik | Chain mail mesh and process for reducing stress |
-
2022
- 2022-03-01 CN CN202210194108.3A patent/CN114601599A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH168207A (en) * | 1933-02-06 | 1934-03-31 | Sebald Albert | Metal link net. |
| CN105188600A (en) * | 2013-03-11 | 2015-12-23 | 伊西康公司 | Single plane tissue repair patch |
| CN111840648A (en) * | 2016-12-28 | 2020-10-30 | 广州迈普再生医学科技股份有限公司 | Multilayer composite tissue repair patch and preparation method thereof |
| US20180271572A1 (en) * | 2017-03-27 | 2018-09-27 | Sunnybrook Research Institute | Miniature or micro-scale conformable chain mail device for orthopaedic fixation, stabilization, and repair |
| US20210178114A1 (en) * | 2019-12-13 | 2021-06-17 | Charles Joseph Brumlik | Chain mail mesh and process for reducing stress |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11013587B2 (en) | Surgical implant | |
| EP2996628B1 (en) | Surgical implant comprising a layer having openings | |
| RU2691307C2 (en) | Surgical implant | |
| EP2797607B1 (en) | Adhesive structure with tissue piercing protrusions on its surface | |
| DE102013004573A1 (en) | Surgical implant | |
| US11612473B2 (en) | Surgical implant and process of manufacturing thereof | |
| CN114601599A (en) | Freely-deformable absorbable metal filling net and preparation method thereof | |
| US20170119515A1 (en) | Surgical Implant | |
| WO2017074671A1 (en) | Surgical implant and process of manufacturing thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |