CN114590475B - A liquid storage release device - Google Patents

Abstract

The embodiment of the disclosure provides a liquid storage release device, which belongs to the field of biochips. The liquid storage release device provided by the embodiment of the disclosure comprises a liquid storage cavity and a fever reducing structure. The liquid storage cavity is provided with a liquid outlet, the liquid outlet can be blocked by a blocking structure, and the blocking structure is made of a thermosensitive material and can be heated and melted; the heating structure is arranged opposite to the liquid outlet, and the heating structure can enable the plugging structure to be melted during operation so as to release liquid in the liquid storage cavity. Because the plugging structure adopts thermosensitive material to make, when consequently needing to release liquid, heating structure work makes the plugging structure melt to liquid in the stock solution cavity can flow from the leakage fluid dram, with the sample contact with react, the stock solution release device that this disclosed embodiment provided can save liquid and automatic release liquid, and simple structure, the operation is safe.

Description

A liquid storage release device

Technical field

The invention belongs to the technical field of biochips, and specifically relates to a liquid storage and release device.

Background technique

Currently, most biological reactions in biodetection chips require the participation of liquids, which can provide a stable and dynamic reaction environment for biomolecules. For most biological reactions, the liquid as the reaction reagent is brought into contact with the sample before detection, so a liquid storage release device is needed to realize the automatic release of the reaction reagent.

However, in the existing technology, the device for releasing the stored liquid has a complex structure or has safety hazards and other problems, making it difficult to implement.

Contents of the invention

The embodiments of the present disclosure are intended to solve at least one of the technical problems existing in the prior art, and provide a liquid storage and release device that can automatically release liquid and has a simple and safe structure.

The technical solution adopted to solve the technical problems of the embodiments of the present disclosure is a liquid storage release device, which includes:

A liquid storage chamber is provided with a liquid discharge port, the liquid discharge port can be blocked by a blocking structure, and the blocking structure is made of heat-sensitive material and can be melted by heat;

A heating structure is provided opposite to the liquid discharge port. When working, the heating structure can melt the blocking structure to release the liquid in the liquid storage chamber.

The liquid storage release device provided by the embodiment of the present disclosure pre-stores liquid in the liquid storage chamber, and uses a blocking structure to seal the liquid discharge port of the liquid storage chamber to store the liquid. Since the blocking structure is made of heat-sensitive materials , therefore when the heating structure is working, the blocking structure is heated and melted, so that the liquid in the liquid storage chamber can flow out from the liquid outlet and contact the sample for reaction. The liquid storage release device provided by the embodiment of the present disclosure can store It can absorb liquid and automatically release liquid. It has simple structure and safe operation.

In some examples, a blocking structure is further included, which is disposed at the liquid drain port to block the liquid drain port, and the blocking structure is made of heat-sensitive material and can be melted by heat.

In some examples, the heating structure includes: a substrate, an electrode layer, an exothermic layer, and an insulating layer arranged in sequence on a side of the substrate close to the liquid storage chamber; the electrode layer includes a first electrode and a second Electrodes, the first electrode and the second electrode are both connected to the exothermic layer, and the first electrode and the second electrode are respectively connected to the positive and negative poles of an external power supply to form a current loop to make the The exothermic layer releases heat to melt the blocking structure;

The heating structure also includes a first opening that penetrates the substrate, the insulating layer and the heat dissipation layer; the orthographic projection of the liquid drain port on the substrate is consistent with the third opening. An opening at least partially overlaps, and orthographic projections of the first electrode and the second electrode on the substrate do not overlap with the first opening.

In some examples, the heating structure is detachably connected to the liquid discharge port of the liquid storage chamber through its first opening.

In some examples, the method further includes: a flow guide structure disposed on a side of the heating structure facing away from the liquid storage chamber; the flow guide structure is provided with at least one communicating first opening on a side close to the heating structure. slot and at least one second slot, and the width of the second slot is less than the width of the first slot;

Each of the at least one first slot extends to an edge of the flow guide structure, and the orthographic projection of the drain port on the flow guide structure is at least partially aligned with the at least one first slot. overlapping.

In some examples, the flow guide structure includes a plurality of spaced apart defining portions, and any two adjacent defining portions define one of the first slot or the second slot.

In some examples, the air guide structure has a circular slot; the limiting portion is a sector-shaped defining portion, and the central angle corresponding to each sector-shaped defining portion is the same; a plurality of the sector-shaped defining portions are provided at each location. In the circular slot, the center of each circle corresponding to the sector-shaped defining portion coincides with the center of the circle of the circular slot, and the radius of each sector-shaped defining portion is smaller than the radius of the circular slot.

In some examples, the liquid storage chamber includes a connected main chamber, a drainage channel, and a connection channel, and the connection channel is connected between the main chamber and the drainage channel; the drainage channel The opening of the channel away from the main chamber serves as the drain port; wherein,

The main chamber and the drainage channel are both cylindrical, and the diameter of the drainage channel is smaller than the diameter of the main chamber; pointing from the main chamber in the direction of the drainage channel, the The diameter of the connecting channel gradually decreases.

In some examples, the connection channel is a rounded connection channel.

In some examples, the liquid storage chamber includes a main chamber and a cover plate, the liquid discharge port is provided at one end of the main chamber, and the cover plate covers the other end of the main chamber; The cover plate is provided with an exhaust port;

The liquid storage release device also includes a waterproof membrane covering the exhaust port for preventing external water vapor from entering the main chamber and preventing liquid in the main chamber from evaporating.

Description of the drawings

Figure 1 is a schematic structural diagram of an embodiment of a liquid storage release device provided by an embodiment of the present disclosure;

Figure 2 is a schematic structural diagram of an embodiment of a liquid storage chamber of a liquid storage release device provided by an embodiment of the present disclosure;

Figure 3 is a schematic structural diagram (front view) of an embodiment of the liquid storage chamber of the liquid storage release device provided by the embodiment of the present disclosure;

Figure 4 is a schematic structural diagram of an embodiment of the heating structure of the liquid storage release device provided by the embodiment of the present disclosure;

Figure 5 is a schematic structural diagram of an embodiment of the flow guide structure of the liquid storage release device provided by the embodiment of the present disclosure;

Figure 6 is a schematic structural diagram of another embodiment of the flow guide structure of the liquid storage release device provided by the embodiment of the present disclosure;

Figure 7 is a schematic diagram of the positional relationship of one embodiment of the flow guide structure of the liquid storage release device provided by the embodiment of the present disclosure;

Figure 8 is a schematic structural diagram of another embodiment of a liquid storage release device provided by an embodiment of the present disclosure;

Figure 9 is a schematic structural diagram (connected state) of another embodiment of the liquid storage release device provided by the embodiment of the present disclosure.

Detailed ways

In order to enable those skilled in the art to better understand the technical solutions of the present invention, the present invention will be described in further detail below in conjunction with the accompanying drawings and specific embodiments.

The shapes and sizes of the various components in the drawings do not reflect the true proportions, but are only intended to facilitate understanding of the contents of the embodiments of the present invention.

Unless otherwise defined, technical terms or scientific terms used in this disclosure shall have the usual meaning understood by a person with ordinary skill in the art to which this disclosure belongs. "First", "second" and similar words used in this disclosure do not indicate any order, quantity or importance, but are only used to distinguish different components. Likewise, similar words such as "a", "an" or "the" do not indicate a quantitative limitation but rather indicate the presence of at least one. Words such as "include" or "comprising" mean that the elements or things appearing before the word include the elements or things listed after the word and their equivalents, without excluding other elements or things. Words such as "connected" or "connected" are not limited to physical or mechanical connections, but may include electrical connections, whether direct or indirect. "Up", "down", "left", "right", etc. are only used to express relative positional relationships. When the absolute position of the described object changes, the relative positional relationship may also change accordingly.

As shown in FIGS. 1 to 4 , embodiments of the present disclosure provide a liquid storage and release device, which includes a liquid storage chamber 1 and a heating structure 2 .

Specifically, the liquid storage chamber 1 is used to store liquid, which may be a commonly used liquid reagent in chemistry or medicine, such as pure water, buffer, detection solution, etc., which is not limited here. The liquid storage chamber 1 is provided with a liquid drain port 1a, and the liquid drain port 1a can be blocked by the blocking structure 4, thereby sealing and storing the liquid. The sealing structure 4 can be made of heat-sensitive material, so that the sealing structure 4 can be melted by heat. The heating structure 2 is disposed opposite to the liquid discharge port 1a of the liquid storage chamber 1. That is to say, the heating structure 2 is disposed close to the liquid discharge port 1a of the liquid storage chamber 1. The heating structure 2 can melt the blocking structure 4 when working. , so that when the liquid in the liquid storage chamber 1 needs to be released, the heating structure 2 works so that the blocking structure 4 is heated and melted, thereby releasing the liquid in the liquid storage chamber 1 so that the liquid can be discharged from the drain port 1a. The sample is exposed to react. In the liquid storage release device provided by the embodiment of the present disclosure, the liquid (such as reagent) to be stored can be introduced into the liquid storage chamber 1 through the liquid discharge port 1a, and a certain volume of liquid is pre-stored in the liquid storage chamber 1 and sealed with The structure 4 is sealed for long-term storage. When detection is required, the heating structure 2 only needs to be operated to melt the blocking structure 4, and then the liquid can be released to react with the sample, so that fresh samples can be collected, and the structure of the liquid storage release device is simple , safe operation.

In some examples, the liquid storage chamber 1 can be made of a shell of various shapes, or a cavity can be made in a single piece of material, and the cavity forms the liquid storage space of the liquid storage chamber 1 . The material of the liquid storage chamber 1 may include a variety of materials, such as polymethyl methacrylate (PMMA), polycarbonate (Polycarbonate, PC) and other materials, which are not limited here.

In some examples, the liquid discharge port 1a can be provided at any position in the liquid storage chamber 1, for example, at a side close to the heating structure 2 in the extension direction of the liquid storage chamber 1. Of course, it can also be at other positions. In the following description, it is assumed that the liquid drain port 1a is disposed on the lower side of the liquid storage chamber 1 as an example. The shape of the drain port 1a may include circles, squares, triangles, etc., and is not limited here. The size of the drain port 1a can also be of various sizes. For example, if the drain port 1a is a circular drain port, the diameter of the drain port 1a can be between [1,3] millimeters, which is not limited here.

In some examples, referring to Figures 2 and 3, the blocking structure 4 can be part of the liquid storage release device provided by the embodiment of the present disclosure, and is pre-set at the liquid discharge port 1a of the liquid storage chamber 1, or can be selected by oneself. Various heat-sensitive materials serve as the blocking structure 4 to seal the liquid discharge port 1a of the liquid storage chamber 1. If the blocking structure 4 is part of the liquid storage release device, the blocking structure 4 is arranged on the discharge port 1a of the liquid storage chamber 1. At the liquid port 1a, specifically, the blocking structure 4 covers the liquid drain port 1a to block the liquid drain port 1a. The shape of the blocking structure 4 can also be set according to the shape of the drain port 1a, so that the blocking structure 4 can be embedded in the drain port 1a and block the drain port 1a. The blocking structure 4 is made of heat-sensitive material, which can melt after being heated. The heat-sensitive material forming the blocking structure 4 is solid at normal temperature (for example, below 45°C) and can melt into a liquid after being heated to a certain temperature (for example, greater than 45°C), and the heat-sensitive material does not interact with the liquid storage chamber. The liquid stored in the chamber 1 reacts, thereby preventing the sealing structure 4 from melting and affecting the purity of the liquid. Moreover, in some embodiments, the density of the heat-sensitive material forming the sealing structure 4 may be less than the density of the liquid stored in the liquid storage chamber 1 , so that the sealing structure 4 melted into a liquid state can float up to The liquid storage chamber 1 is on the side facing away from the liquid discharge port 1a. The heat-sensitive material forming the blocking structure 4 can include a variety of materials, such as paraffin, which is solid at room temperature and blocks the column drain port 1a. If liquid needs to be released, the heating structure 2 is heated to melt the paraffin. It is a liquid. Due to the low density of paraffin, the melted paraffin will float to the side of the liquid storage chamber 1 away from the drain port 1a due to the density effect, and because the liquid storage chamber 1 is away from the drain port 1a, it is far away from the heating structure 2 , so the temperature is lower. After the melted paraffin floats and encounters a lower-temperature liquid, it will condense into a solid state, and the paraffin does not react with the liquid. Therefore, the liquid in the liquid storage chamber 1 is discharged from the drain port 1a, and the condensation is The solid paraffin will remain in the liquid storage chamber 1 and will not flow out of the liquid drain port 1a, thereby preventing paraffin from clogging the liquid drain port 1a and preventing paraffin from contaminating the liquid. Of course, the blocking structure 4 can also be made of other heat-sensitive materials, which is not limited here.

In some examples, referring to FIGS. 1 and 4 , in the liquid storage release device provided by embodiments of the present disclosure, the heating structure 2 may include a substrate 21 , and an electrode layer sequentially disposed on the side of the substrate 21 close to the liquid storage chamber 1 22. Exothermic layer 23, insulating layer 24, electrode layer 22 is provided on the side of the substrate 1 close to the liquid storage chamber 1. The electrode layer 22 may include a first electrode 221 and a second electrode 222, and the first electrode 221 is connected to the exothermic layer. 23. The second electrode 222 is also connected to the exothermic layer 23, and one of the first electrode 221 and the second electrode 222 is connected to the positive electrode of the external power supply, and the other is connected to the negative electrode of the external power supply, so that the first electrode 221, releases heat. The layer 23, the second electrode 222, and the external power supply form a current loop, and the current is loaded to the exothermic layer 23, causing the exothermic layer 23 to release heat (Joule heat) to melt the blocking structure 4 to release the liquid.

Furthermore, continuing to refer to Figures 1 and 4, in order to allow the liquid to flow out, the heating structure 2 may also include a first opening 2a, which penetrates the substrate 21, the insulating layer 22 and the heat dissipation layer 23, and the electrode layer The orthographic projection of the first electrode 221 in 22 on the substrate 21 does not overlap with the first opening 2a, and the orthographic projection of the second electrode 222 in the electrode layer 22 on the substrate 21 also does not overlap with the first opening 2a. The first opening 2a is arranged opposite to the liquid discharge port 1a of the liquid storage chamber 1, that is, the orthographic projection of the liquid discharge port 1a on the substrate 21 at least partially overlaps the first opening 2a, so that the liquid can flow out from the liquid discharge port 1a to The solution holding the sample flows into the first opening 2a and reacts with the sample.

In some examples, continuing to refer to FIGS. 1 and 4 , the exothermic layer 23 may be made of materials with a thermoelectric effect, that is, materials capable of converting most of the electrical energy into thermal energy. For example, the material of the exothermic layer 23 may include indium tin oxide. , at least one of nickel-chromium alloy, iron-chromium-aluminum alloy, barium titanate ceramic, silicon carbide, lanthanum chromate, zirconium oxide, and molybdenum disilicide. The above materials can convert electrical energy into thermal energy after conducting electricity, releasing a large amount of The heat causes the sealing structure 4 to melt. In the following description, the material of the heat dissipation layer 23 is indium tin oxide as an example, but this does not limit the present invention.

In some examples, continuing to refer to FIGS. 1 and 4 , in the liquid release device provided by embodiments of the present disclosure, since the blocking structure 4 melted into a liquid state will float to the upper part of the liquid storage chamber 1 and condense into a solid, therefore , while releasing heat, the heat release layer 23 can control the amount of heat it releases, so that the heat released only melts the blocking structure 4, but does not cause the liquid storage chamber 1 to deviate from the liquid on the side of the drain port 1a. The temperature is too high, causing the material of the blocking structure 4 to be unable to condense into a solid. In some examples, the coverage area of the heat dissipation layer 23 can be set according to the required heat. For example, see FIG. 4 , the heat dissipation layer 23 is annular and is only provided around the periphery of the first opening 2 a without covering the entire Substrate 1. Specifically, the orthographic projection of the heat dissipation layer 23 on the substrate 1 surrounds the first opening 2 a, has no overlap with the first opening 2 a, and partially overlaps with the orthographic projection of the first electrode 221 and the second electrode 222 on the substrate 1 , without completely covering the first electrode 221 and the second electrode 222, so that the heat released by the heat release layer 23 only affects the blocking structure 4 at the drain port 1a above the first opening 2a without causing storage. The temperature of the liquid on the side of the liquid chamber 1 away from the liquid discharge port 1a is too high.

In some examples, the first electrode 221 and the second electrode 222 of the electrode layer 22 may be strip electrodes, which are respectively disposed on both sides of the first opening 2a and overlap with the pattern of the heat dissipation layer 23. Of course, the first The electrode 221 and the second electrode 22 can also be electrodes of other shapes, which are not limited here.

In some examples, the insulating layer 24 is disposed on the side of the electrode layer 22 close to the liquid storage chamber 1 , and the insulating layer 24 can protect the heat dissipation layer 23 and the pattern structure of the electrode layer 22 . The material of the insulating layer 24 may include a variety of materials, such as silicon oxide (such as silicon dioxide) or silicon nitride (such as silicon nitride). Of course, it may also be other insulating materials, which are not limited here.

In some examples, the insulating layer 24 may have a first via hole (not shown in the figure) and a second via hole (not shown in the figure), and the heating structure 2 may also include a first connecting line (not shown in the figure). (out) and a second connection line (not shown in the figure), one end of the first connection line is connected to the first electrode 221 through the first via hole, and the other end of the first connection line is connected to the positive pole (or negative pole) of the external power supply, and at the same time In this way, one end of the second connection line is connected to the second electrode 222 through the second via hole, and the other end of the second connection line is connected to the negative electrode (or positive electrode) of the external voltage. Of course, the first electrode 221 and the second electrode 222 can also be connected to the external power supply in other ways, which is not limited here.

In some examples, the substrate 21 may include various types of substrates, such as glass substrates, quartz substrates, etc., as long as metal or non-metal materials can be made on the substrate 21 through processes such as sputtering, which is not limited here.

In some examples, as shown in Figure 1, the first opening 2a of the heating structure 2 and the liquid outlet 1a of the liquid storage chamber 1 can be coaxially arranged and fixedly connected, for example, with optical glue (OCA glue). catch. Alternatively, the heating structure 2 can also be detached and connected to the liquid drain port 1a of the liquid storage chamber 1 with the first opening 2a. For example, a clamp holder is provided in the peripheral area of the first opening 2a, and a clamp holder is provided in the peripheral area of the liquid discharge port 1a. The heating structure 2 and the liquid storage chamber 1 are detached and connected by disassembling the clamp holder and the buckle.

In some examples, referring to FIGS. 2 and 3 , the liquid storage chamber 1 may include a connected main chamber 11 , a drainage channel 13 and a connecting channel 12 . The connecting channel 12 is connected between the main chamber 11 and the drainage channel 13 Specifically, the second end opening of the main chamber 11 is closer to the first end opening of the connecting channel 12 than the first end opening of the main chamber 11 , and the second end opening of the main chamber 11 is closer to the connecting channel 12 The first end opening is tightly connected, so that the diameter of the second end opening of the main chamber 11 is the same as the diameter of the first end opening of the connecting channel 12; the first end opening of the drainage channel 13 is smaller than the second opening of the drainage channel 13. The end opening is close to the second end opening of the connection channel 12, and the first end opening of the drainage channel 13 is closely connected to the second end opening of the connection channel 12, so that the diameter of the first end opening of the drainage channel 13 is consistent with the diameter of the connection channel 12. The diameters of the second end openings are the same; the second end opening of the drainage channel 13 (that is, the opening facing away from the main chamber 11) serves as the drainage port 1a. Among them, the main chamber 11 and the drainage channel 13 are both cylindrical cavities, and the diameter of the drainage channel 13 is smaller than the diameter of the main chamber 11 , and the connecting channel 12 serves as a transition channel between the drainage channel 13 and the main chamber 11 , from the main chamber 11 to the direction of the drainage channel 13, the diameter of the connecting channel 12 gradually decreases, that is, the diameter of the connecting channel 12 decreases from the diameter of the main chamber 11 to the diameter of the drainage channel 13, and the connecting channel 12 The extending direction of the wall surface has a certain angle with the extending direction of the wall surface of the main chamber 11, so that the liquid can be discharged from the liquid outlet 1a along the inclined wall surface of the connecting channel 12, thereby reducing the residual liquid.

In some examples, see Figures 2 and 3, the connection channel 12 is a rounded connection channel, that is, the connection channel 12 is an arc surface, and the bending direction is away from the inside of the liquid storage chamber 1, so that The main chamber 11 can be smoothly transitioned to the drainage channel 13. Since the connecting channel 12 is a rounded connecting channel, the cavity of the liquid storage chamber 1 formed by connecting the main chamber 11, the connecting channel 12 and the drainage channel 13 has no The corners where liquid is likely to remain can make the main chamber 11 smoothly transition to the drainage channel 13, thereby reducing the amount of liquid remaining in the cavity of the liquid storage chamber 1 and reducing the waste of liquid.

In some examples, referring to FIGS. 2 and 3 , the liquid storage chamber 1 includes a main chamber 11 and a cover 14 . Specifically, the liquid storage chamber 1 may include a connected main chamber 11 , a drainage channel 13 and a Connecting the channel 12 and the cover 14, the drain port 1a is set at one end of the main chamber 11 (specifically, it can be set at the end of the drain channel 13 facing away from the main chamber 11), while the other end of the main chamber 11 is open, and the cover A plate 14 covers the other end of the main chamber 11 . When liquid needs to be stored, the drain port 1a can be sealed with the blocking structure 4 first, then the cover 14 is opened, the liquid is introduced into the main chamber 11, and then the cover 14 is closed to seal the main chamber 11. Further, the cover 14 can be provided with an exhaust port 1b, and the liquid storage release device can also include a waterproof membrane 5. The waterproof membrane 5 covers the exhaust port. The waterproof membrane 5 can prevent external water vapor from entering the main chamber 11, and prevent the main chamber 11 from entering. The liquid in the chamber 11 evaporates and can balance the air pressure inside and outside the main chamber 11 . Specifically, the waterproof membrane 5 can be disposed on the side of the cover 14 away from the main chamber 11 to facilitate disassembly; it can also be disposed on the side of the cover 15 close to the main chamber 11 to reduce the probability of the waterproof membrane 5 falling off.

Optionally, the waterproof membrane 5 can be made of various types of materials, such as polytetrafluoroethylene, and of course other materials, which are not limited here.

Optionally, the main chamber 11 and the cover plate 14 can be an integral structure, so that the liquid to be stored can be injected from the exhaust port 1b, and then the waterproof membrane 5 is provided on the exhaust port 1b, which is not limited here.

In some examples, referring to Figures 5-8, the liquid storage release device provided by the embodiment of the present disclosure also includes a flow guide structure 3. The flow guide structure 3 is provided on the side of the heating structure 2 facing away from the liquid storage chamber 1. The flow guide structure 3 3 is used to introduce the released liquid into the container holding the sample. The flow guide structure 3 is provided with at least one first slot 31 and at least one second slot 32 on the side close to the heating structure 2, and each of the at least one first slot 31 extends to the guide structure 3. The edge of the flow structure 3, and the orthographic projection of the liquid outlet 1a of the liquid storage structure 1 on the flow guide structure 3 at least partially overlaps with at least one first slot 31, and the first opening 2a of the heating structure 2 is in the flow guide structure 3. The orthographic projection on the structure 3 also at least partially overlaps with at least one first slot 31, so that after the liquid is released, it flows from the drain port 1a to the first opening 2a, and then flows into the first slot from the first opening 2a. 31, and then flows into the container holding the sample from the edge of the flow guide structure 3 along the extension direction of the first slot 31. The width of the second groove 32 is smaller than the width of the first groove 31, so that the liquid flows to the flow guide structure 3, and the first groove 31 will form a capillary flow channel and have a capillary effect. When the liquid needs to be released, the heating structure 2 heats the blocking structure 4 to melt it into a liquid state. Most of the material of the liquid blocking structure 4 will rise to the upper part of the liquid storage cavity 1 due to buoyancy, and during the rising process Due to the temperature drop, it condenses into a solid form and stays in the liquid storage cavity 1. However, there may also be a small amount of material in the liquid state of the blocking structure 4 that adheres to the drain port 1a and rushes into the first slot 31 of the guide structure 3 through the first opening 2a as the released liquid, causing an opening. The slot is clogged, but since the flow guide structure 3 is also provided with a second slot 32, the second slot 32 is connected with the first slot 31, and the second slot 32 is a capillary flow channel, and the water flowing into the first slot 31 The material of the blocking structure 4 in liquid state will be preferentially sucked into the narrower second slots 32 due to capillary action. The number of the second slots 32 can be set according to the volume of the material flowing into the blocking structure 4 of the flow guide structure 3. This can prevent the material of the blocking structure 4 from blocking the first slot 31 and preventing the liquid from flowing out.

In some examples, the width of the first slot 31 is [1,2] mm, the depth of the first slot 31 is [1,2] mm, and/or the width of the second slot 32 is [0.1, 1) mm, the depth of the second slot 31 is [0.1, 1) mm. Of course, the width and depth of the first groove 31 and the width and depth of the second groove 32 can be other values, which can be set according to the volume and type of the liquid and the volume and type of material of the blocking structure 4. In This is not limited.

In some examples, the number of the first slots 31 can also be one or more. If the number of the first slots 31 is one, the container holding the sample is disposed in the first slot 31 extending to the flow guide. It suffices at the end of the edge of the structure 3; if the number of the first slots 32 is multiple, the diameter of the container holding the sample can be larger than the size of the entire guide structure 3, and it can be set at the end of the guide structure 3 downward, so that the liquid flowing out of the plurality of first slots 32 can flow into the container. The number of the second slots 32 may also be one or more, and may be set according to the volume of the material flowing into the blocking structure 4 of the flow guide structure 3 . In FIG. 5 , the flow guide structure 3 is provided with one first slot 31 and two second slots 32 as an example.

In some examples, the shapes of the first slot 31 and the second slot 32 may be unrestricted. For example, the first slot 31 and/or the second slot 32 may be rectangular, circular, annular, etc., and the first The slot 31 and the second slot 32 may be an integral slot, or may be defined by a plurality of limiting parts. For example, referring to FIG. 6 , the air guide structure 3 may include a plurality of spaced apart defining portions 031 , and any two adjacent defining portions 031 define a first slot 31 or a second slot 32 .

In some examples, the limiting portion 031 can be in various shapes, such as rectangular, circular, fan-shaped, etc., continuing to refer to Figure 6, the air guide structure 3 has a circular slot 032, and the plurality of limiting portions 031 are fan-shaped defining portions, Moreover, the central angle corresponding to each sector-shaped limiting portion is the same, that is, the arc lengths of the arc sides of the plurality of limiting portions 031 are also the same. A plurality of sector-shaped limiting portions (ie, limiting portions 031) are provided in the circular slot 032. The center of each sector-shaped defining portion coincides with the center of the circular slot 032, and the radius of each sector-shaped defining portion is smaller than the circle. The radius of the two adjacent sector-shaped defining parts defines a first slot 31 or a second slot 32 .

Specifically, referring to FIG. 7 , in order to illustrate the positional relationship between the sector-shaped limiting portion 031 and the circular slot 032 , FIG. 7 only shows a diagram in which a sector-shaped limiting portion 031 is disposed in the circular slot 032 , and other definitions are shown in FIG. 7 . The arrangement of the portion 031 is the same as the limiting portion 031 . The sector-shaped limiting portion 031 includes a short arc side 031a, a long arc side 031b and two sides 031c extending in the radial direction. The first ends of the two sides 031c are respectively connected to both sides of the short arc side 031a. The two sides 031c The second ends of are respectively connected to both sides of the long arc side 031b. The center of the circle corresponding to the sector-shaped limiting portion 031 coincides with the center of the circular slot 032 (shown as center 0 in Figure 7). Therefore, the sector-shaped limiting portion 031 The extending direction of the side (that is, the extending direction of the sector-shaped radius R1) coincides with the extending direction of the radius R2 of the circular slot 032, and the length of the radius R1 of the sector-shaped limiting portion 031 is smaller than the length of the circular slot 032. Radius R2, the long arc edge 031b of the sector-shaped limiting portion 031 is located close to the circular edge of the circular slot 032, so there is a certain distance between the long arc side 031b of the sector-shaped limiting portion 031 and the circular edge of the circular slot 032, multiple The sector-shaped limiting portion 031 is arranged along the direction of the circular edge of the circular slot 032. Therefore, the long arc edges 031b of the plurality of sector-shaped restricting portions 031 and the round edges of the circular slot 032 define an annular sub-slot 312, and multiple The short arc edge 031b of the sector-shaped limiting portion 031 defines a circular hole slot 313, and a plurality of sector-shaped limiting portions 031 are arranged between the annular sub-slot 312 and the circular hole slot 313. Two adjacent limiting portions 031 defines a linear sub-slot 311 of the first slot 31, or defines a linear second slot 32. One end of the second slot 32 is connected to the circular sub-slot 313, and the other end is connected to the annular sub-slot 312, and the extending direction of the second slot 32 is the radial direction of the circular slot 032, that is, a plurality of second slots 32 Arranged radially in the circular slot 032 along each radius of the circular slot 032, the linear sub-slot 311, the annular sub-slot 312 and the circular sub-slot 313 form the first slot 31, and the linear sub-slot 311 One end of the slot 311 extends to the edge of the guide structure 3 , the other end communicates with the annular sub-slot 312 through the annular sub-slot 312 , and then extends to the circular hole sub-slot 313 and communicates with the circular hole sub-slot 313 . In this embodiment, referring to Figures 8 and 9, the orthographic projection of the liquid outlet 1a of the liquid storage structure 1 on the guide structure 3 at least partially overlaps with the circular hole sub-slot 313, and the first opening 2a of the heating structure 2 The orthographic projection on the flow guide structure also at least partially overlaps with the circular hole sub-slot 313. In some examples, the circular hole sub-slot 313, the liquid discharge port 1a, and the first opening 2a can be coaxially arranged. Therefore, referring to Figure 9, the liquid discharge port 1a of the liquid storage structure 1 is connected to the first opening 2a of the heating structure 2, and the first opening 2a of the heating structure 2 is connected to the circle of the first slot 31 of the flow guide structure 3. The hole slot 313 is connected. When the liquid needs to be released, the heat release layer 23 of the heating structure 3 conducts electricity and releases heat, so that the blocking structure 4 at the liquid discharge port 1a melts into a liquid state, and the liquid in the liquid storage chamber 1 is released from The liquid discharge port 1a flows into the circular hole sub-slot 313 through the first opening 2a, and then flows out of the guide structure 3 through the linear sub-slot 311. Among them, most of the material of the sealing structure 4 in a liquid state floats to the top of the liquid storage chamber 1 and condenses into a solid, remaining in the liquid storage chamber 1. A small part may follow the liquid through the drain port 1a and the third An opening 2a punches into the round hole slot 313, and there are connected second slots 32 around the round hole slot 313. Under capillary action, the material of the liquid sealing structure 4 will be sucked into the second opening preferentially. In the groove 32, the plurality of radially arranged second grooves 32 can absorb the material of the sealing structure 4 in a liquid state to the maximum extent without affecting the inflow of liquid from the circular holes of the first groove 31 into the grooves 313. The linear sub-slot 311 flows out again, thereby preventing the blocking structure 4 from blocking the first slot 31 , thereby improving the reliability of the liquid release device provided by the embodiment of the present disclosure.

Of course, the number, shape, and arrangement of the first slots 31 and the second slots 32 of the air guide structure 3 can also be in other ways, which are not limited here.

It can be understood that the above embodiments are only exemplary embodiments adopted to illustrate the principles of the present invention, but the present invention is not limited thereto. For those of ordinary skill in the art, various modifications and improvements can be made without departing from the spirit and essence of the present invention, and these modifications and improvements are also regarded as the protection scope of the present invention.

Claims (10)

1. A reservoir delivery device, comprising:

the liquid storage cavity is provided with a liquid outlet, the liquid outlet can be blocked by a blocking structure, and the blocking structure is made of a heat-sensitive material and can be heated and melted;

the heating structure is arranged opposite to the liquid outlet, and can enable the plugging structure to be melted when in operation so as to release liquid in the liquid storage cavity;

the flow guiding structure is arranged at one side of the heating structure, which is away from the liquid storage cavity; at least one first slot and at least one second slot which are communicated are arranged on one side, close to the heating structure, of the flow guiding structure, and the width of the second slot is smaller than that of the first slot; and the orthographic projection of the liquid outlet on the flow guiding structure is at least partially overlapped with the at least one first slot.

2. The reservoir delivery device of claim 1, further comprising: the plugging structure is arranged at the liquid outlet so as to plug the liquid outlet, and is made of a heat-sensitive material and can be heated and melted.

3. The reservoir delivery device of claim 1, wherein the heating structure comprises: the substrate is sequentially arranged on the electrode layer, the heat release layer and the insulating layer on one side of the substrate, which is close to the liquid storage cavity; the electrode layer comprises a first electrode and a second electrode, the first electrode and the second electrode are both connected with the heat release layer, and the first electrode and the second electrode are respectively connected with the anode and the cathode of an external power supply so as to form a current loop to enable the heat release layer to release heat to melt the plugging structure; the heating structure further includes a first opening penetrating the substrate, the insulating layer, and the heat release layer; the orthographic projection of the liquid drain on the substrate is at least partially overlapped with the first opening, and the orthographic projections of the first electrode and the second electrode on the substrate are not overlapped with the first opening.

4. A reservoir release device as defined in claim 3, wherein the heating structure is detachably connected to the drain port of the reservoir chamber through the first opening thereof.

5. The fluid reservoir delivery apparatus of any of claims 1-4, wherein each of the at least one first slot extends to an edge of the flow directing structure.

6. The fluid reservoir delivery apparatus of claim 5, wherein the flow directing structure comprises a plurality of spaced apart defining portions, any two adjacent defining portions defining one of the first slot or the second slot.

7. The fluid reservoir delivery device of claim 6, wherein the flow directing structure has a circular slot; the limiting parts are sector limiting parts, and the central angles corresponding to the sector limiting parts are the same; the plurality of sector limiting parts are arranged in the circular groove, the circle center corresponding to each sector limiting part coincides with the circle center of the circular groove, and the radius of each sector limiting part is smaller than the radius of the circular groove.

8. The liquid storage release device according to claim 1, wherein the liquid storage chamber includes a main chamber, a liquid discharge passage, and a connection passage that are communicated, the connection passage being connected between the main chamber and the liquid discharge passage; the opening of the liquid discharge channel, which is away from the main chamber, is used as the liquid discharge port; wherein,

the main chamber and the liquid discharge channel are cylindrical, and the caliber of the liquid discharge channel is smaller than that of the main chamber; the caliber of the connecting channel gradually decreases from the main chamber to the direction of the liquid discharge channel.

9. The reservoir delivery device of claim 8, wherein the connecting channel is a rounded connecting channel.

10. The liquid storage release device according to claim 1, wherein the liquid storage chamber includes a main chamber and a cover plate, the liquid discharge port is provided at one end of the main chamber, and the cover plate covers the other end of the main chamber; the cover plate is provided with an exhaust port;

the reservoir release device further includes a waterproof membrane covering the vent for preventing external moisture from entering the main chamber and preventing liquid in the main chamber from volatilizing.