CN114566276A - Lung color Doppler ultrasound-based training method and device for child pneumonia auxiliary diagnosis model - Google Patents
Lung color Doppler ultrasound-based training method and device for child pneumonia auxiliary diagnosis model Download PDFInfo
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Abstract
本申请提供了一种基于肺部彩超的儿童肺炎辅助诊断模型的训练方法和训练装置,训练方法包括:获取包括多个儿童肺炎患者的彩超图像的诊疗信息数据库;根据数据库获取多个样本集合;对每个样本集合中的训练集进行训练处理,获得训练模型;根据每个样本集合的测试集对训练模型进行检验,获得训练模型的准确度;基于多个训练模型的准确度,确定诊断模型;其中,每个样本集合包括训练集及对应的测试集。本申请的训练方法获得的诊断模型准确度较高,能够为临床医生的诊断提供帮助,减少漏诊和误诊率,还能够将该诊断模型作为医生学习诊断的工具,也能够为医生的快速成长提供巨大的推动力。
The present application provides a training method and training device for an auxiliary diagnosis model of childhood pneumonia based on lung color Doppler ultrasound. The training method includes: acquiring a diagnosis and treatment information database including color Doppler images of multiple pediatric pneumonia patients; acquiring a plurality of sample sets according to the database; Perform training processing on the training set in each sample set to obtain a training model; test the training model according to the test set of each sample set to obtain the accuracy of the training model; determine the diagnostic model based on the accuracy of multiple training models ; wherein, each sample set includes a training set and a corresponding test set. The diagnostic model obtained by the training method of the present application has high accuracy, which can help clinicians in diagnosis, reduce the rate of missed diagnosis and misdiagnosis, and can also use the diagnostic model as a tool for doctors to learn and diagnose, and can also provide medical services for the rapid growth of doctors. Huge boost.
Description
技术领域technical field
本申请涉及医学计算机技术领域,特别地涉及一种基于肺部彩超的儿童肺炎辅助诊断模型的训练方法和训练装置。The present application relates to the technical field of medical computers, and in particular, to a training method and a training device for a child pneumonia auxiliary diagnosis model based on lung color ultrasound.
背景技术Background technique
据世界卫生组织(WHO)报道,小儿肺炎是儿童致死的首要原因。2015年WHO估算全球约有92万多名儿童死于肺炎,其中5岁以下儿童约占15%。肺炎诊断有时非常困难,因为症状会根据孩子的年龄和感染的原因有不同的变化。此外,有些症状不仅仅指向儿童肺炎,也可以是其他疾病的相关临床表现。肺炎作为婴幼儿威胁性极高的病症,一旦发现,应给予准确的诊断,然后对症治疗,诊断越早、准确性越高越好,有利于提升患儿的治愈率,对于患儿诊断方法的选择应给予重点关注。特别是社区对于小儿肺炎的诊断,更加需要准确的肺炎诊断手段。According to the World Health Organization (WHO), pediatric pneumonia is the leading cause of death in children. In 2015, WHO estimated that more than 920,000 children worldwide died of pneumonia, of which children under the age of 5 accounted for about 15%. Diagnosing pneumonia can sometimes be difficult because symptoms can vary depending on the child's age and the cause of the infection. In addition, some symptoms do not only point to childhood pneumonia, but can also be related clinical manifestations of other diseases. Pneumonia is a very threatening disease for infants and young children. Once found, an accurate diagnosis should be given, and then symptomatic treatment should be given. The earlier the diagnosis and the higher the accuracy, the better, which will help improve the cure rate of children. Choices should be given a strong focus. In particular, for the diagnosis of pneumonia in children, the community needs more accurate pneumonia diagnosis methods.
然而,以往小儿肺炎的主要影像学检查方法是胸部X射线和CT检查,针对于同一张胸部X射线和CT检查的医学影像,不同时间点或不同医生的判断结果不一致性很高,就具有很大的观察者差异。However, in the past, the main imaging methods for pediatric pneumonia were chest X-ray and CT examination. For the same medical image of chest X-ray and CT examination, the judgment results of different time points or different doctors are highly inconsistent, which has a high degree of inconsistency. large observer differences.
发明内容SUMMARY OF THE INVENTION
为了解决或至少部分地解决上述技术问题,本申请提供了一种基于肺部彩超的儿童肺炎辅助诊断模型的训练方法,其包括:获取包括多个儿童肺炎患者的彩超图像的诊疗信息数据库;根据数据库获取多个样本集合;对每个样本集合中的训练集进行训练处理,获得训练模型;根据每个样本集合的测试集对训练模型进行检验,获得训练模型的准确度;基于多个训练模型的准确度,确定诊断模型;其中,每个样本集合包括训练集及对应的测试集。In order to solve or at least partially solve the above-mentioned technical problems, the present application provides a training method for a child pneumonia auxiliary diagnosis model based on lung color Doppler ultrasound, which includes: acquiring a diagnosis and treatment information database including color Doppler images of multiple pediatric pneumonia patients; The database obtains multiple sample sets; performs training processing on the training set in each sample set to obtain a training model; tests the training model according to the test set of each sample set to obtain the accuracy of the training model; based on multiple training models The accuracy of the diagnostic model is determined; wherein, each sample set includes a training set and a corresponding test set.
本申请基于肺部彩超的儿童肺炎辅助诊断模型的训练方法,包括:获取包括多个儿童肺炎患者的彩超图像的诊疗信息数据库,数据库的来源可以为某医院的儿科,在就诊期间所获得的儿童肺炎患者就诊资料,数据库可以为诊断模型的训练提供数据支持,尽可能地提升诊断模型的准确性。The training method of the child pneumonia auxiliary diagnosis model based on lung color ultrasound in the present application includes: acquiring a diagnosis and treatment information database including color ultrasound images of multiple children with pneumonia patients. The database can provide data support for the training of the diagnosis model and improve the accuracy of the diagnosis model as much as possible.
接着,根据数据库获取多个样本集合,对于每个样本集合而言,均具有训练集和对应的测试集,一个样本集合可以包含数据库的所有数据,也可以仅包含部分数据。训练集中的诊疗信息用于模型训练,测试集的数量用于模型准确的测试,经过训练后获得的训练模型,再经由测试集的检验,从而能够得到训练模型的准确度。Next, multiple sample sets are obtained according to the database. For each sample set, there is a training set and a corresponding test set. One sample set may contain all the data of the database, or may only contain part of the data. The diagnosis and treatment information in the training set is used for model training, and the number of test sets is used to test the accuracy of the model. The training model obtained after training is then tested on the test set to obtain the accuracy of the training model.
其中,对每个样本集合中的训练集进行训练处理,获得训练模型,然后在根据每个样本集合的测试集对训练模型进行检验,获得训练模型的准确度。由于样本集合的数量为多个,当对每个样本集合均进行训练处理时,则会获得多个训练模型,那么对多个训练模型分别进行检验之后,则会获得多个训练模型的准确度。The training process is performed on the training set in each sample set to obtain a training model, and then the training model is tested according to the test set of each sample set to obtain the accuracy of the training model. Since the number of sample sets is multiple, when each sample set is trained, multiple training models will be obtained, and after the multiple training models are tested separately, the accuracy of multiple training models will be obtained. .
最后,基于多个训练模型的准确度,确定诊断模型,诊断模型的准确度较高,能够为医生的诊断提供帮助,减轻儿科医生工作压力,提高各级医院对于肺炎的诊断率,辅助临床医生减少漏诊和误诊率,还能够将该诊断模型作为医生学习诊断的工具,也能够为医生的快速成长提供巨大的推动力。Finally, based on the accuracy of multiple training models, the diagnosis model is determined. The accuracy of the diagnosis model is high, which can help doctors in diagnosis, reduce the work pressure of pediatricians, improve the diagnosis rate of pneumonia in hospitals at all levels, and assist clinicians. Reducing the rate of missed diagnosis and misdiagnosis, the diagnostic model can also be used as a tool for doctors to learn diagnosis, and it can also provide a huge impetus for the rapid growth of doctors.
值得说明的是,本申请所提供的基于肺部彩超的儿童肺炎辅助诊断模型的训练方法涉及获取数据,而并不作为诊断手段。It is worth noting that the training method for the auxiliary diagnosis model of childhood pneumonia based on lung color ultrasound provided in this application involves acquiring data, not as a means of diagnosis.
可选地,每个诊疗信息包括超声图像、对应的检验结果以及对应的诊断信息。Optionally, each diagnosis and treatment information includes an ultrasound image, a corresponding test result, and corresponding diagnostic information.
可选地,获得由多个儿童肺炎患者的诊疗信息构成的数据库的步骤,具体包括:获取多个儿童肺炎患者的诊疗信息;对多个诊疗信息中的超声图像进行图像预处理,获得数据库;其中,图像预处理包括裁剪、翻转、旋转、缩放处理。Optionally, the step of obtaining a database consisting of diagnosis and treatment information of a plurality of children with pneumonia specifically includes: obtaining diagnosis and treatment information of a plurality of children with pneumonia; performing image preprocessing on the ultrasound images in the plurality of diagnosis and treatment information to obtain a database; Among them, image preprocessing includes cropping, flipping, rotation, and scaling.
可选地,根据数据库获取多个样本集合的步骤,具体包括:在数据库随机获取多个样本集合;其中,任两个样本集合中训练集和测试集的比例不同。Optionally, the step of acquiring multiple sample sets according to the database specifically includes: randomly acquiring multiple sample sets from the database; wherein the ratios of the training set and the test set in any two sample sets are different.
可选地,多个训练模型包括第一训练模型和第二训练模型,基于多个训练模型的准确度,确定诊断模型的步骤,具体包括:第一训练模型的准确度大于第二训练模型的准确度,确定第一训练模型为诊断模型。Optionally, the multiple training models include a first training model and a second training model, and the step of determining the diagnosis model based on the accuracy of the multiple training models specifically includes: the accuracy of the first training model is greater than that of the second training model. Accuracy, determine that the first training model is a diagnostic model.
可选地,诊断模型的网络结构包括AlexNet网络结构、Resnet18网络结构或Resnet50网络结构。Optionally, the network structure of the diagnosis model includes an AlexNet network structure, a Resnet18 network structure or a Resnet50 network structure.
本申请还提供了一种基于肺部彩超的儿童肺炎辅助诊断模型的训练装置,其特征在于,包括:The application also provides a training device for a child pneumonia auxiliary diagnosis model based on lung color Doppler ultrasound, characterized in that it includes:
获取模块,用于获取包括多个儿童肺炎患者的彩超图像的诊疗信息数据库,根据数据库获取多个样本集合;an acquisition module, used for acquiring a diagnosis and treatment information database including color Doppler ultrasound images of multiple children with pneumonia, and acquiring multiple sample sets according to the database;
训练模块,用于对每个样本集合中的训练集进行训练处理,获得训练模型;The training module is used to perform training processing on the training set in each sample set to obtain the training model;
测试模块,根据每个样本集合的测试集对训练模型进行检验,获得训练模型的准确度;The test module tests the training model according to the test set of each sample set to obtain the accuracy of the training model;
确定模块,基于多个训练模型的准确度,确定诊断模型;Determine the module, determine the diagnosis model based on the accuracy of the multiple training models;
其中,每个样本集合包括训练集及对应的测试集。Wherein, each sample set includes a training set and a corresponding test set.
本申请中用于儿童肺炎辅助诊断模型训练装置包括获取模块、训练模块、测试模块和确定模块,其中,获取模块用于获取包括多个儿童肺炎患者的彩超图像的诊疗信息数据库,数据库的来源可以为某医院的儿科,在就诊期间所获得的儿童肺炎患者就诊资料,数据库可以为诊断模型的训练提供数据支持,尽可能地提升诊断模型的准确性。The apparatus for training an auxiliary diagnosis model for childhood pneumonia in this application includes an acquisition module, a training module, a test module and a determination module, wherein the acquisition module is used to acquire a diagnosis and treatment information database including color ultrasound images of multiple children with pneumonia patients, and the source of the database can be For the pediatric department of a hospital, the data of children with pneumonia obtained during the consultation period, the database can provide data support for the training of the diagnosis model, and improve the accuracy of the diagnosis model as much as possible.
接着,获取模块还能够根据数据库获取多个样本集合,对于每个样本集合而言,均具有训练集和对应的测试集,一个样本集合可以包含数据库的所有数据,也可以仅包含部分数据。训练集中的诊疗信息用于模型训练,测试集的数量用于模型准确的测试,经过训练后获得的训练模型,再经由测试集的检验,从而能够得到训练模型的准确度。Next, the acquisition module can also acquire multiple sample sets according to the database. For each sample set, there are training sets and corresponding test sets. A sample set can contain all the data of the database, or only part of the data. The diagnosis and treatment information in the training set is used for model training, and the number of test sets is used to test the accuracy of the model. The training model obtained after training is then tested on the test set to obtain the accuracy of the training model.
其中,训练模块能够每个样本集合中的训练集进行训练处理,获得训练模型,然后再通过训练模块,根据每个样本集合的测试集对训练模型进行检验,获得训练模型的准确度。由于样本集合的数量为多个,当对每个样本集合均进行训练处理时,则会获得多个训练模型,那么对多个训练模型分别进行检验之后,则会获得多个训练模型的准确度。The training module can perform training processing on the training set in each sample set to obtain a training model, and then through the training module, test the training model according to the test set of each sample set to obtain the accuracy of the training model. Since the number of sample sets is multiple, when each sample set is trained, multiple training models will be obtained, and after the multiple training models are tested separately, the accuracy of multiple training models will be obtained. .
最后,确定模块能够基于多个训练模型的准确度,确定诊断模型,也就是说,再多个训练模型中选取准确度较高的训练模型作为诊断模型,诊断模型的准确度较高,能够为医生的诊断提供帮助,减轻儿科医生工作压力,提高各级医院对于肺炎的诊断率,辅助临床医生减少漏诊和误诊率,还能够将该诊断模型作为医生学习诊断的工具,也能够为医生的快速成长提供巨大的推动力。Finally, the determination module can determine the diagnosis model based on the accuracy of the multiple training models, that is to say, select the training model with higher accuracy from the multiple training models as the diagnosis model, the accuracy of the diagnosis model is higher, and can be It provides help in the diagnosis of doctors, reduces the work pressure of pediatricians, improves the diagnosis rate of pneumonia in hospitals at all levels, and assists clinicians to reduce the rate of missed diagnosis and misdiagnosis. Growth provides a huge boost.
可选地,获取模块还用于:在数据库随机获取多个样本集合,其中,任两个样本集合中训练集和测试集的比例不同。Optionally, the obtaining module is further configured to: randomly obtain multiple sample sets from the database, wherein the proportions of the training set and the test set in any two sample sets are different.
本申请还提供了一种计算机设备,包括存储器、处理器及存储在存储器上并可在处理器上运行的计算机程序,其特征在于:处理器用于执行如前述基于肺部彩超的儿童肺炎辅助诊断模型的训练方法的步骤。The present application also provides a computer device, including a memory, a processor, and a computer program stored in the memory and running on the processor, characterized in that the processor is used to perform the aforementioned auxiliary diagnosis of childhood pneumonia based on lung color Doppler ultrasound The steps of the model's training method.
本申请中的计算机设备,其包含的处理器用于执行上述任一设计中基于肺部彩超的儿童肺炎辅助诊断模型的训练方法的步骤,因而,该计算机设备能够实现该基于肺部彩超的儿童肺炎辅助诊断模型的训练方法的全部有益效果,在此不再赘述。In the computer equipment in the present application, the processor it includes is used to execute the steps of the training method of the child pneumonia auxiliary diagnosis model based on lung color Doppler in any of the above designs, and thus, the computer equipment can realize the child pneumonia based on lung color Doppler ultrasound. All the beneficial effects of the training method of the auxiliary diagnosis model will not be repeated here.
本申请还提供了一种计算机可读存储介质,其上存储有计算机程序,其特征在于:计算机程序被处理器执行时实现了如前述基于肺部彩超的儿童肺炎辅助诊断模型的训练方法的步骤。The present application also provides a computer-readable storage medium on which a computer program is stored, and is characterized in that: when the computer program is executed by the processor, the steps of the training method for the child pneumonia auxiliary diagnosis model based on lung color ultrasound as described above are realized. .
本申请中的计算机可读存储介质,其上存储的计算机程序被处理器执行时实现了如上述任一设计中的基于肺部彩超的儿童肺炎辅助诊断模型的训练方法的步骤,因而该计算机可读存储介质能够实现该训练方法全部的有益效果,不再赘述。The computer-readable storage medium in the present application, when the computer program stored on it is executed by the processor, realizes the steps of the training method of the child pneumonia auxiliary diagnosis model based on lung color ultrasound in any of the above designs, so the computer can Reading the storage medium can achieve all the beneficial effects of the training method, which will not be repeated.
附图说明Description of drawings
为了更清楚地说明本申请的实施方式,下面将对相关的附图做出简单介绍。可以理解,下面描述中的附图仅用于示意本申请的一些实施方式,本领域普通技术人员还可以根据这些附图获得本文中未提及的许多其他的技术特征和连接关系等。In order to illustrate the embodiments of the present application more clearly, a brief introduction to the related drawings will be made below. It can be understood that the drawings in the following description are only used to illustrate some embodiments of the present application, and those of ordinary skill in the art can also obtain many other technical features and connection relationships not mentioned herein based on these drawings.
图1为根据本申请的一个实施例的基于肺部彩超的儿童肺炎辅助诊断模型的训练方法的流程示意图。FIG. 1 is a schematic flowchart of a training method for a child pneumonia auxiliary diagnosis model based on lung color Doppler ultrasound according to an embodiment of the present application.
图2为根据本申请的另一个实施例的基于肺部彩超的儿童肺炎辅助诊断模型的训练方法的流程示意图。FIG. 2 is a schematic flowchart of a training method for a child pneumonia auxiliary diagnosis model based on lung color Doppler ultrasound according to another embodiment of the present application.
图3为根据本申请的一个实施例的基于肺部彩超的儿童肺炎辅助诊断模型的训练装置的示意框图。FIG. 3 is a schematic block diagram of a training device for a child pneumonia auxiliary diagnosis model based on lung color ultrasound according to an embodiment of the present application.
图4为根据本申请的一个实施例中计算机设备的示意框图。FIG. 4 is a schematic block diagram of a computer device according to an embodiment of the present application.
具体实施方式Detailed ways
下面将结合本申请实施例中的附图,对本申请实施例中的技术方案进行详细说明。The technical solutions in the embodiments of the present application will be described in detail below with reference to the accompanying drawings in the embodiments of the present application.
本申请的发明人发现,在相关技术中,对于儿童肺炎的诊断主要依赖于医学影像,然而,针对于同一医学影像,不同的观察者的判断结果不一致性很高,存在漏诊、误诊的可能。The inventors of the present application found that, in the related art, the diagnosis of pneumonia in children mainly relies on medical images. However, for the same medical image, the judgment results of different observers are highly inconsistent, and there is a possibility of missed diagnosis and misdiagnosis.
有鉴于此,本申请提供了一种基于肺部彩超的儿童肺炎辅助诊断模型的训练方法,以辅助临床医生减少漏诊和误诊率,同时也能够降低临床医生工作强度,提高诊断准确性以及诊断效率。In view of this, the present application provides a training method for a child pneumonia auxiliary diagnosis model based on lung color Doppler ultrasound, so as to assist clinicians to reduce the rate of missed diagnosis and misdiagnosis, and at the same time, it can also reduce the work intensity of clinicians, and improve the accuracy and efficiency of diagnosis. .
实施方式一Embodiment 1
如图1所示,根据本申请的一个实施例的基于肺部彩超的儿童肺炎辅助诊断模型的训练方法的流程示意图。其中,训练方法包括:As shown in FIG. 1 , a schematic flowchart of a training method for a child pneumonia auxiliary diagnosis model based on lung color Doppler ultrasound according to an embodiment of the present application. Among them, the training methods include:
S102,获取包括多个儿童肺炎患者的彩超图像的诊疗信息数据库;S102, acquiring a diagnosis and treatment information database including color ultrasound images of multiple children with pneumonia;
S104,根据数据库获取多个样本集合;S104, obtaining multiple sample sets according to the database;
S106,对每个样本集合中的训练集进行训练处理,获得训练模型;S106, perform training processing on the training set in each sample set to obtain a training model;
S108,根据每个样本集合的测试集对训练模型进行检验,获得训练模型的准确度;S108, test the training model according to the test set of each sample set to obtain the accuracy of the training model;
S110,基于多个训练模型的准确度,确定诊断模型;S110, determining a diagnosis model based on the accuracy of the multiple training models;
其中,每个样本集合包括训练集及对应的测试集。Wherein, each sample set includes a training set and a corresponding test set.
本申请基于肺部彩超的儿童肺炎辅助诊断模型的训练方法,包括:获取包括多个儿童肺炎患者的彩超图像的诊疗信息数据库,数据库的来源可以为某医院的儿科,在就诊期间所获得的儿童肺炎患者就诊资料,数据库可以为诊断模型的训练提供数据支持,尽可能地提升诊断模型的准确性。The training method of the child pneumonia auxiliary diagnosis model based on lung color ultrasound in the present application includes: acquiring a diagnosis and treatment information database including color ultrasound images of multiple children with pneumonia patients. The database can provide data support for the training of the diagnosis model and improve the accuracy of the diagnosis model as much as possible.
接着,根据数据库获取多个样本集合,对于每个样本集合而言,均具有训练集和对应的测试集,一个样本集合可以包含数据库的所有数据,也可以仅包含部分数据。训练集中的诊疗信息用于模型训练,测试集的数量用于模型准确的测试,经过训练后获得的训练模型,再经由测试集的检验,从而能够得到训练模型的准确度。Next, multiple sample sets are obtained according to the database. For each sample set, there is a training set and a corresponding test set. One sample set may contain all the data of the database, or may only contain part of the data. The diagnosis and treatment information in the training set is used for model training, and the number of test sets is used to test the accuracy of the model. The training model obtained after training is then tested on the test set to obtain the accuracy of the training model.
其中,对每个样本集合中的训练集进行训练处理,获得训练模型,然后在根据每个样本集合的测试集对训练模型进行检验,获得训练模型的准确度。由于样本集合的数量为多个,当对每个样本集合均进行训练处理时,则会获得多个训练模型,那么对多个训练模型分别进行检验之后,则会获得多个训练模型的准确度。The training process is performed on the training set in each sample set to obtain a training model, and then the training model is tested according to the test set of each sample set to obtain the accuracy of the training model. Since the number of sample sets is multiple, when each sample set is trained, multiple training models will be obtained, and after the multiple training models are tested separately, the accuracy of multiple training models will be obtained. .
最后,基于多个训练模型的准确度,确定诊断模型,诊断模型的准确度较高,能够为医生的诊断提供帮助,减轻儿科医生工作压力,提高各级医院对于肺炎的诊断率,辅助临床医生减少漏诊和误诊率,还能够将该诊断模型作为医生学习诊断的工具,也能够为医生的快速成长提供巨大的推动力。Finally, based on the accuracy of multiple training models, the diagnosis model is determined. The accuracy of the diagnosis model is high, which can help doctors in diagnosis, reduce the work pressure of pediatricians, improve the diagnosis rate of pneumonia in hospitals at all levels, and assist clinicians. Reducing the rate of missed diagnosis and misdiagnosis, the diagnostic model can also be used as a tool for doctors to learn diagnosis, and it can also provide a huge impetus for the rapid growth of doctors.
可选地,每个诊疗信息包括超声图像、对应的检验结果以及对应的诊断信息。Optionally, each diagnosis and treatment information includes an ultrasound image, a corresponding test result, and corresponding diagnostic information.
在该实施例中,数据库内包含多个诊疗信息,每个诊疗信息对应一个患者,每个诊疗信息包括每个患者对应的超声图像、检验结果和诊断信息。In this embodiment, the database contains a plurality of diagnosis and treatment information, each diagnosis and treatment information corresponds to a patient, and each diagnosis and treatment information includes ultrasound images, test results and diagnosis information corresponding to each patient.
其中,超声图像是采用超声成像技术获得的。具体地,超声成像是利用超声扫描人体,通过对反射信号的接收、处理,以获得体内器官的图像。常用的超声仪器有多种:A型(幅度调制型)是以波幅的高低表示反射信号的强弱,显示的是一种“回声图”。超声图像具有无创、无放射性的特点,可以有效改善患者受辐射损伤的情况,具有可行性,且超声检查具有简便、快捷、多方向性以及限制性少的优点。Wherein, the ultrasound image is obtained by using ultrasound imaging technology. Specifically, ultrasound imaging uses ultrasound to scan the human body, and obtains images of internal organs by receiving and processing reflected signals. There are many kinds of commonly used ultrasonic instruments: type A (amplitude modulation type) indicates the strength of the reflected signal by the amplitude of the wave, and it shows an "echo graph". Ultrasound images are non-invasive and non-radioactive, which can effectively improve the radiation damage of patients, and is feasible. Ultrasound examination has the advantages of simplicity, speed, multi-directionality and less restriction.
其中,检验结果包括患者住院期间的血液检查结果。Among them, the test results include blood test results during the patient's hospitalization.
其中,诊断信息包括医生根据超声图像、检验结果对患者的病情做出诊断结论。具体地,诊断信息包括气胸、肺间质综合征、肺实变、急性肺损伤、呼吸窘迫综合征、新生儿暂时性呼吸增快症和肺炎等。The diagnostic information includes the doctor making a diagnosis conclusion on the patient's condition according to the ultrasound image and the test result. Specifically, the diagnostic information includes pneumothorax, interstitial pulmonary syndrome, lung consolidation, acute lung injury, respiratory distress syndrome, neonatal transient tachypnea, pneumonia, and the like.
具体来说,健康人体肺组织中含有大量的气体和少量的水,胸膜和肺组织交界面构成软组织与气体之间的界面,当声波透过此界面时产生强反射,而小儿肺炎疾病主要病理变化是肺组织呈渗出性改变,正常肺泡充气被渗出液、炎症细胞等充填,此为超声诊断肺炎的基础。Specifically, healthy human lung tissue contains a large amount of gas and a small amount of water. The interface between the pleura and lung tissue constitutes the interface between soft tissue and gas. When sound waves pass through this interface, a strong reflection occurs. The main pathological pathology of pediatric pneumonia is The change is that the lung tissue is exudative, and the normal alveolar air is filled with exudate, inflammatory cells, etc., which is the basis for the diagnosis of pneumonia by ultrasound.
当肺部出现炎症时,肺含气减少,而炎症渗出增多,气液间声阻抗增大,超声在气液交界处发生强烈混响从而形成彗星尾征,向远场延伸即为B线。B线的数量取决于肺通气损失的程度,其回声的强度随着吸气运动增加。其中,间距≤3mm的多条B线,称为B3线,其与胸部CT显示的毛玻璃影相关,提示有肺泡性肺水肿的可能,而间距>7mm的多条B线,称为B7线,则提示有小叶间隔增厚的可能。若患儿病情发展至肺泡内气体消失,充满大量纤维蛋白及红细胞、白细胞等渗出物时,成为超声诊断肺实变的病理学基础。实变肺与胸膜直接接触或透过水构成声窗时,即为超声检查提供了条件。When there is inflammation in the lungs, the air content in the lungs decreases, the inflammatory exudation increases, and the acoustic impedance between air and liquid increases, and the ultrasound produces strong reverberation at the gas-liquid junction, forming a comet tail sign, and extending to the far field is the B line. . The number of B-lines depends on the degree of lung ventilation loss, and the intensity of its echoes increases with inspiratory motion. Among them, multiple B lines with a distance of ≤3mm are called B3 lines, which are related to ground glass shadows displayed on chest CT, indicating the possibility of alveolar pulmonary edema, while multiple B lines with a distance of >7mm are called B7 lines. This suggests the possibility of interlobular septal thickening. If the child's disease progresses to the point where the gas in the alveoli disappears and is filled with a large amount of fibrin, red blood cells, white blood cells and other exudates, it becomes the pathological basis for the diagnosis of lung consolidation by ultrasound. When the consolidated lung is in direct contact with the pleura or through water to form an acoustic window, it provides conditions for ultrasonography.
实施方式二Embodiment 2
如图2所示,根据本申请的另一个实施例的基于肺部彩超的儿童肺炎辅助诊断模型的训练方法的流程示意图。其中,训练方法包括:As shown in FIG. 2 , according to another embodiment of the present application, a schematic flowchart of a training method for a child pneumonia auxiliary diagnosis model based on lung color ultrasound. Among them, the training methods include:
S202,获取多个儿童肺炎患者的诊疗信息;S202, obtaining diagnosis and treatment information of multiple children with pneumonia;
S204,对多个诊疗信息中的超声图像进行图像预处理,获得数据库;S204, performing image preprocessing on the ultrasound images in the plurality of diagnosis and treatment information to obtain a database;
S206,根据数据库获取多个样本集合;S206, obtaining multiple sample sets according to the database;
S208,对每个样本集合中的训练集进行训练处理,获得训练模型;S208, performing training processing on the training set in each sample set to obtain a training model;
S210,根据每个样本集合的测试集对训练模型进行检验,获得训练模型的准确度;S210, test the training model according to the test set of each sample set to obtain the accuracy of the training model;
S212,基于多个训练模型的准确度,确定诊断模型。S212, determining a diagnosis model based on the accuracy of the multiple training models.
在该实施例中,获得由多个儿童肺炎患者的诊疗信息构成的数据库的步骤,具体包括:获取多个儿童肺炎患者的诊疗信息,每个儿童肺炎患者的诊疗信息都包括超声图像、对应的检验结果和对应的诊断信息。在后续的训练处理过程中,由多个诊疗信息构成的样本集合作为训练基础,因此,诊疗信息的精准度尤为重要。In this embodiment, the step of obtaining a database consisting of diagnosis and treatment information of a plurality of children with pneumonia specifically includes: obtaining diagnosis and treatment information of a plurality of children with pneumonia, where the diagnosis and treatment information of each child pneumonia patient includes ultrasound images, corresponding Test results and corresponding diagnostic information. In the subsequent training process, a sample set composed of multiple diagnosis and treatment information is used as the training basis. Therefore, the accuracy of diagnosis and treatment information is particularly important.
其中,诊疗信息中的检验结果和诊断信息均为数据文本构成,精度比较高,可以直接进行训练处理,然而,超声图像由于不同的影像学设备限制或者是影像医生的操作熟练程度等因素影响,超声图像的精度具有提升空间。Among them, the test results and diagnosis information in the diagnosis and treatment information are all composed of data text, and the accuracy is relatively high, which can be directly processed by training. There is room for improvement in the accuracy of ultrasound images.
本实施例中对于每个诊疗信息中的超声图像进行图像预处理,从而可以降低超声图像中的噪声,弥补超声图像的数据缺陷,提高超声图像的精度,进而提升训练处理的高效性。In this embodiment, image preprocessing is performed on the ultrasound image in each diagnosis and treatment information, so as to reduce noise in the ultrasound image, make up for data defects of the ultrasound image, improve the accuracy of the ultrasound image, and further improve the efficiency of training processing.
值得说明的是,在超声图像中,主要的噪声来自于散斑(speckle),他是由于声束在不均匀微细组织的散射所引起的干涉作用造成的,他在图像中表现为颗粒状,并不反映实际的组织结构,但却影响了图像的细节分辨能力。这不利于图像的定量分析,因此需对图像中的散斑噪声进行抑制。It is worth noting that, in the ultrasound image, the main noise comes from speckle, which is caused by the interference effect caused by the scattering of the sound beam in the uneven fine tissue, which appears as granular in the image, It does not reflect the actual organizational structure, but affects the detail resolution ability of the image. This is not conducive to the quantitative analysis of the image, so it is necessary to suppress the speckle noise in the image.
可选地,图像预处理包括裁剪、翻转、旋转、缩放处理。Optionally, the image preprocessing includes cropping, flipping, rotation, and scaling.
其中,在训练处理进行之前,为了减少数据计算的工作量,提高训练速度,可以对感兴趣的特征部分进行原图片的裁剪,这样每张超声图像既保留了待提取的特征集,又缩小了整体的尺寸,可有效缩短训练模型耗费的时间,提升训练效率。Among them, before the training process, in order to reduce the workload of data calculation and improve the training speed, the original image can be cropped for the feature part of interest, so that each ultrasound image not only retains the feature set to be extracted, but also reduces the size of the original image. The overall size can effectively shorten the time spent training the model and improve the training efficiency.
可选地,根据数据库获取多个样本集合的步骤,具体包括:在数据库随机获取多个样本集合;其中,任两个样本集合中训练集和测试集的比例不同。Optionally, the step of acquiring multiple sample sets according to the database specifically includes: randomly acquiring multiple sample sets from the database; wherein the ratios of the training set and the test set in any two sample sets are different.
在该实施例中,根据数据库获取多个样本集合的步骤,具体包括:在数据库随机获取多个样本集合,从而尽可能地保证针对于每个样本集合中训练集在进行训练处理时的特有性质,尽可能地获得不同的训练模型,为得到最终的诊断模型提供更多的选择。In this embodiment, the step of obtaining multiple sample sets according to the database specifically includes: randomly obtaining multiple sample sets from the database, so as to ensure as much as possible the unique properties of the training set in each sample set during training processing , to obtain different training models as much as possible to provide more choices for obtaining the final diagnostic model.
可选地,任意两个样本集合中训练集和测试集的比例不同,即任意两个样本集合的构成不同,此时,针对于这两个样本集合而言,其所获得的训练模型也具有各异性。Optionally, the proportions of the training set and the test set in any two sample sets are different, that is, the composition of any two sample sets is different, at this time, for these two sample sets, the obtained training model also has heterogeneity.
比如,在数据库中获取第一样本集合、第二样本集合和第三样本集合,其中,第一样本集合中训练集和测试集的比例为5:5,第二样本集合中训练集和测试集的比例为8:2,第三样本集合中训练集和测试集的比例为9:1,那么,针对于第一样本集合的测试集进行训练可以获得第一训练模型,针对于第二样本集合的测试集进行训练可以获得第二训练模型,针对于第三样本集合的测试集进行训练可以获得第三训练模型,然后,再通过各自的测试集对所获得的训练模型的准确性进行检验,获得各自对应的准确度,根据多个训练模型的准确度,从而确定诊断模型。For example, the first sample set, the second sample set and the third sample set are obtained in the database, wherein the ratio of the training set and the test set in the first sample set is 5:5, and the training set and the test set in the second sample set are The ratio of the test set is 8:2, and the ratio of the training set and the test set in the third sample set is 9:1. Then, the first training model can be obtained by training on the test set of the first sample set. The second training model can be obtained by training on the test set of the second sample set, the third training model can be obtained by training on the test set of the third sample set, and then the accuracy of the obtained training model can be checked through the respective test sets The test is performed to obtain the respective corresponding accuracies, and the diagnostic model is determined according to the accuracies of the multiple training models.
当诊断模型应用于实际的超声检查过程中时,将患者的肺部超声图像输入诊断模型中,则可以辅助医生减少漏诊和误诊率,起到早诊断、早治疗的目的。When the diagnostic model is applied to the actual ultrasound examination process, the patient's lung ultrasound images are input into the diagnostic model, which can assist doctors to reduce the rate of missed diagnosis and misdiagnosis, and achieve the purpose of early diagnosis and early treatment.
可选地,多个训练模型包括第一训练模型和第二训练模型,基于多个训练模型的准确度,确定诊断模型的步骤,具体包括:第一训练模型的准确度大于第二训练模型的准确度,确定第一训练模型为诊断模型。Optionally, the multiple training models include a first training model and a second training model, and the step of determining the diagnosis model based on the accuracy of the multiple training models specifically includes: the accuracy of the first training model is greater than that of the second training model. Accuracy, determine that the first training model is a diagnostic model.
在该实施例中,多个训练模型包括第一训练模型和第二训练模型,基于多个训练模型的准确度,确定诊断模型的步骤,具体包括:第一训练模型的准确度大于第二训练模型的准确度,确定第一训练模型为诊断模型,诊断模型为准确度较高的训练模型。In this embodiment, the multiple training models include a first training model and a second training model, and the step of determining the diagnosis model based on the accuracy of the multiple training models specifically includes: the accuracy of the first training model is greater than that of the second training model The accuracy of the model determines that the first training model is a diagnosis model, and the diagnosis model is a training model with higher accuracy.
其中,训练模型的准确度较高则表明其效能优异,能够很好地根据超声图像获得诊断信息,从而能够有效辅助临床医生,降低工作强度。Among them, the higher accuracy of the training model indicates that its performance is excellent, and the diagnostic information can be obtained according to the ultrasound images, which can effectively assist clinicians and reduce work intensity.
值得说明的是,多个训练模型的数量可以为正整数,不设上限,可以根据实际情况选择样本集合的数量,从而获得对应数量的训练模型,然后在多个训练模型中择优选择准确度较高,以作为最终的诊断模型。It is worth noting that the number of multiple training models can be a positive integer without an upper limit. The number of sample sets can be selected according to the actual situation, so as to obtain the corresponding number of training models, and then select the best among the multiple training models. high as the final diagnostic model.
可选地,诊断模型的网络结构包括AlexNet网络结构、Resnet18网络结构或Resnet50网络结构。Optionally, the network structure of the diagnosis model includes an AlexNet network structure, a Resnet18 network structure or a Resnet50 network structure.
实施方式三Embodiment 3
如图3示出了本申请的一个实施例的基于肺部彩超的儿童肺炎辅助诊断模型的训练装置的示意框图。如图3所示,训练装置300包括:FIG. 3 shows a schematic block diagram of a training device for a child pneumonia auxiliary diagnosis model based on lung color ultrasound according to an embodiment of the present application. As shown in FIG. 3, the training device 300 includes:
获取模块302,用于获取包括多个儿童肺炎患者的彩超图像的诊疗信息数据库,根据数据库获取多个样本集合;The acquisition module 302 is used to acquire a diagnosis and treatment information database including color Doppler ultrasound images of multiple children with pneumonia, and acquire multiple sample sets according to the database;
训练模块304,用于对每个样本集合中的训练集进行训练处理,获得训练模型;A training module 304, configured to perform training processing on the training set in each sample set to obtain a training model;
测试模块306,根据每个样本集合的测试集对训练模型进行检验,获得训练模型的准确度;The testing module 306 checks the training model according to the test set of each sample set to obtain the accuracy of the training model;
确定模块308,基于多个训练模型的准确度,确定诊断模型;determining module 308, determining a diagnosis model based on the accuracy of the multiple training models;
其中,每个样本集合包括训练集及对应的测试集。Wherein, each sample set includes a training set and a corresponding test set.
本申请中基于肺部彩超的儿童肺炎辅助诊断模型的训练装置300包括获取模块302、训练模块304、测试模块306和确定模块308,其中,获取模块302用于获取包括多个儿童肺炎患者的彩超图像的诊疗信息数据库,数据库的来源可以为某医院的儿科,在就诊期间所获得的儿童肺炎患者就诊资料,数据库可以为诊断模型的训练提供数据支持,尽可能地提升诊断模型的准确性。The training device 300 of the child pneumonia auxiliary diagnosis model based on lung color Doppler in the present application includes an acquisition module 302, a training module 304, a test module 306 and a determination module 308, wherein the acquisition module 302 is used to obtain the color Doppler ultrasound including multiple children with pneumonia patients The image diagnosis and treatment information database, the source of the database can be the pediatric department of a hospital, the medical treatment information of children with pneumonia obtained during the consultation period, the database can provide data support for the training of the diagnosis model, and improve the accuracy of the diagnosis model as much as possible.
接着,获取模块302还能够根据数据库获取多个样本集合,对于每个样本集合而言,均具有训练集和对应的测试集,一个样本集合可以包含数据库的所有数据,也可以仅包含部分数据。训练集中的诊疗信息用于模型训练,测试集的数量用于模型准确的测试,经过训练后获得的训练模型,再经由测试集的检验,从而能够得到训练模型的准确度。Next, the acquisition module 302 can also acquire multiple sample sets according to the database, and each sample set has a training set and a corresponding test set, and a sample set may contain all the data of the database, or only a part of the data. The diagnosis and treatment information in the training set is used for model training, and the number of test sets is used to test the accuracy of the model. The training model obtained after training is then tested on the test set to obtain the accuracy of the training model.
其中,训练模块304能够每个样本集合中的训练集进行训练处理,获得训练模型,然后再通过测试模块306,根据每个样本集合的测试集对训练模型进行检验,获得训练模型的准确度。由于样本集合的数量为多个,当对每个样本集合均进行训练处理时,则会获得多个训练模型,那么对多个训练模型分别进行检验之后,则会获得多个训练模型的准确度。The training module 304 can perform training processing on the training set in each sample set to obtain a training model, and then pass the testing module 306 to test the training model according to the test set of each sample set to obtain the accuracy of the training model. Since the number of sample sets is multiple, when each sample set is trained, multiple training models will be obtained, and after the multiple training models are tested separately, the accuracy of multiple training models will be obtained. .
最后,确定模块308能够基于多个训练模型的准确度,确定诊断模型,诊断模型的准确度较高,能够为医生的诊断提供帮助,减轻儿科医生工作压力,提高各级医院对于肺炎的诊断率,辅助临床医生减少漏诊和误诊率,还能够将该诊断模型作为医生学习诊断的工具,也能够为医生的快速成长提供巨大的推动力。Finally, the determination module 308 can determine the diagnosis model based on the accuracy of the multiple training models. The diagnosis model has a high accuracy, which can provide help for the doctor's diagnosis, reduce the work pressure of the pediatrician, and improve the diagnosis rate of pneumonia in hospitals at all levels. , assisting clinicians to reduce the rate of missed diagnosis and misdiagnosis, and can also use the diagnostic model as a tool for doctors to learn diagnosis, and can also provide a huge impetus for the rapid growth of doctors.
可选地,获取模块302还用于:在数据库随机获取多个样本集合,其中,任两个样本集合中训练集和测试集的比例不同。Optionally, the obtaining module 302 is further configured to: randomly obtain multiple sample sets from the database, wherein the ratios of the training set and the test set in any two sample sets are different.
可选地,每个诊疗信息包括超声图像、对应的检验结果以及对应的诊断信息。Optionally, each diagnosis and treatment information includes an ultrasound image, a corresponding test result, and corresponding diagnostic information.
可选地,获取模块302还用于:获取多个儿童肺炎患者的诊疗信息;对多个诊疗信息中的超声图像进行图像预处理,获得数据库;其中,图像预处理包括裁剪、翻转、旋转、缩放处理。Optionally, the obtaining module 302 is further configured to: obtain the diagnosis and treatment information of multiple children with pneumonia; perform image preprocessing on the ultrasound images in the multiple diagnosis and treatment information to obtain a database; wherein, the image preprocessing includes cropping, flipping, rotating, Zoom processing.
可选地,多个训练模型包括第一训练模型和第二训练模型,确定模块308还用于:第一训练模型的准确度大于第二训练模型的准确度,确定第一训练模型为诊断模型。Optionally, the multiple training models include a first training model and a second training model, and the determining module 308 is further configured to: the accuracy of the first training model is greater than the accuracy of the second training model, and determining that the first training model is a diagnostic model .
可选地,诊断模型的网络结构包括AlexNet网络结构、Resnet18网络结构或Resnet50网络结构。Optionally, the network structure of the diagnosis model includes an AlexNet network structure, a Resnet18 network structure or a Resnet50 network structure.
实施方式四Embodiment 4
如图4示出了本申请的一个实施例中计算机设备400的示意框图。其中,计算机设备400包括存储器402、处理器404及存储在存储器402上并可在处理器404上运行的计算机程序,其特征在于:处理器404用于执行如前述基于肺部彩超的儿童肺炎辅助诊断模型的训练方法的步骤。FIG. 4 shows a schematic block diagram of a computer device 400 in an embodiment of the present application. The computer device 400 includes a memory 402, a processor 404, and a computer program stored in the memory 402 and running on the processor 404, characterized in that: the processor 404 is used to perform the aforementioned lung color ultrasound-based child pneumonia assistance Steps in the training method of the diagnostic model.
本申请中的计算机设备400,其包含的处理器404用于执行上述任一设计中基于肺部彩超的儿童肺炎辅助诊断模型的训练方法的步骤,因而,该计算机设备400能够实现该基于肺部彩超的儿童肺炎辅助诊断模型的训练方法的全部有益效果,在此不再赘述。In the computer device 400 in the present application, the processor 404 included in it is configured to execute the steps of the training method of the child pneumonia auxiliary diagnosis model based on lung color ultrasound in any of the above designs. Therefore, the computer device 400 can realize the lung-based diagnosis All the beneficial effects of the training method of the color Doppler ultrasound auxiliary diagnosis model of childhood pneumonia will not be repeated here.
实施方式五Embodiment 5
本申请还提供了一种计算机可读存储介质,其上存储有计算机程序,其特征在于:计算机程序被处理器执行时实现了如前述基于肺部彩超的儿童肺炎辅助诊断模型的训练方法的步骤。The present application also provides a computer-readable storage medium on which a computer program is stored, and is characterized in that: when the computer program is executed by the processor, the steps of the training method for the child pneumonia auxiliary diagnosis model based on lung color ultrasound as described above are realized. .
本申请中的计算机可读存储介质,其上存储的计算机程序被处理器执行时实现了如上述任一设计中的基于肺部彩超的儿童肺炎辅助诊断模型的训练方法的步骤,因而该计算机可读存储介质能够实现该训练方法全部的有益效果,不再赘述。The computer-readable storage medium in the present application, when the computer program stored on it is executed by the processor, realizes the steps of the training method of the child pneumonia auxiliary diagnosis model based on lung color ultrasound in any of the above designs, so the computer can Reading the storage medium can achieve all the beneficial effects of the training method, which will not be repeated.
对于本领域技术人员而言,显然本申请不限于上述示范性实施例的细节,而且在不背离本申请的精神或基本特征的情况下,能够以其他的具体形式实现本申请。因此,无论从哪一点来看,均应将实施例看作是示范性的,而且是非限制性的,本申请的范围由所附权利要求而不是上述说明限定,因此旨在将落在权利要求的等同要件的含义和范围内的所有变化囊括在本申请内。不应将权利要求中的任何附图标记视为限制所涉及的权利要求。It will be apparent to those skilled in the art that the present application is not limited to the details of the above-described exemplary embodiments, but that the present application may be implemented in other specific forms without departing from the spirit or essential characteristics of the present application. Accordingly, the embodiments are to be regarded in all respects as illustrative and not restrictive, and the scope of the application is to be defined by the appended claims rather than the foregoing description, which is therefore intended to fall within the scope of the claims. All changes that come within the meaning and scope of equivalents to are included in this application. Any reference signs in the claims shall not be construed as limiting the involved claim.
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