CN114427174A - A kind of preparation method of filter paper-based flexible sensor with antibacterial function - Google Patents

Abstract

The invention discloses a preparation method of a filter paper-based flexible sensor with an antibacterial function, which comprises the steps of preparing a graphene oxide solution and an AgNWS aqueous solution, mixing and stirring Ascorbic Acid (AA) and the graphene oxide solution uniformly, adding the mixture into the AgNWS aqueous solution to obtain a mixed solution, transferring the mixed solution to a polytetrafluoroethylene reaction kettle, putting the polytetrafluoroethylene reaction kettle into a drying oven, reacting at a set temperature and time to obtain a black mixed solution, carrying out multiple centrifugal washing on the black mixed solution by using deionized water and absolute ethyl alcohol to remove impurities to obtain an Ag-rGO solution, carrying out ultrasonic crushing on the Ag-rGO solution to obtain an Ag-rGO composite solution uniformly dispersed in the deionized water, dripping the Ag-rGO composite solution into filter paper, and carrying out suction filtration and drying on the filter paper to obtain Ag-rGO filter paper; putting the Ag-rGO filter paper into a pressing groove of a hot press to enable the Ag-rGO filter paper to be better compounded, cutting the Ag-rGO filter paper into an ideal shape after the Ag-rGO filter paper is dried, gluing copper wires to two ends by using silver, putting the copper wires into a drying oven for drying, finally coating a layer of PDMS on the surface of the Ag-rGO filter paper, and drying the Ag-rGO filter paper in the drying oven to obtain the Ag-rGO filter paper flexible sensor.

Description

A kind of preparation method of filter paper-based flexible sensor with antibacterial function

technical field

The invention relates to the technical field of flexible electronics, in particular to a preparation method of a filter paper-based flexible sensor with antibacterial function.

Background technique

In recent years, the field of flexible electronics has developed rapidly. Flexible sensors are becoming important applications in future robotics, in vitro diagnostics and energy harvesting. As an important part of wearable sensors, flexible sensors have set off a global research upsurge. However, in practical applications, the developed flexible sensors still have many problems, such as poor ductility of metal materials, poor stability of organic materials, poor conductivity of inorganic materials, 1D structure is more suitable for small deformation, 2D structure measurement range is narrow, 3D structure is more Suitable for large deformations, making them difficult to be practically applied.

Graphene-based materials have excellent electrical conductivity, excellent mechanical properties, and high light transmittance, making them an ideal sensitive material. The AgNWS also changes the contact mode between the rGO sheets and increases the conduction path, thereby improving the sensitivity of the sensor. PDMS films are due to their excellent elasticity, in addition to their excellent biocompatibility, intrinsically high stretchability, chemical inertness, stability, and variable mechanical properties.

After development, the application range of flexible sensors is more and more widely used in various fields, such as bionic machines, human body and so on. This requires a method that can perfectly fit on the top of different objects to be tested without affecting it. In addition, it is attached to any part of human skin. During use, it will be stained with sweat, sebum and other various human secretions, and it will also be contaminated by dirt in the environment. These dirts are a good source of nutrients for various microorganisms, especially under constant temperature and humidity conditions, and become a good environment for the reproduction of various microorganisms. As a result, the Ag component in the Ag-rGO-PDMS flexible sensor excellently inhibited the reproduction of bacteria.

SUMMARY OF THE INVENTION

In order to overcome the above-mentioned defects in the prior art, the present invention provides a preparation method of a filter paper-based flexible sensor with antibacterial function, which has a microstructure with extremely high biocompatibility and great compressibility, and can ensure that the sensor has The stable and high sensitivity can also inhibit the reproduction and growth of bacteria. The fabrication method is simple to operate, low in cost, and has low requirements on the operating environment, which opens up a new way for the fabrication of flexible sensor microstructures.

Technical solutions

A preparation method of a filter paper-based flexible sensor with antibacterial function, comprising the following steps:

(1) Ag-rGO composite solution is prepared by one-step solvent hydrothermal method: graphene oxide solution and AgNWS aqueous solution are prepared, ascorbic acid (AA) and graphene oxide solution are mixed and stirred evenly and then added to the AgNWS aqueous solution to obtain a mixed solution;

(2) the described mixed solution in the step (1) is transferred in the polytetrafluoroethylene reactor and put into the baking oven, after the reaction finishes at the set temperature and time, obtain the black mixed solution, use deionized water and The black mixed solution was centrifuged and washed with absolute ethanol for several times to remove impurities to obtain an Ag-rGO solution;

(3) ultrasonically pulverizing the Ag-rGO solution in step (2) to obtain an Ag-rGO composite solution uniformly dispersed in deionized water, and dropping the Ag-rGO composite solution uniformly dispersed in deionized water onto filter paper , and then the filter paper is filtered and dried to obtain Ag-rGO filter paper;

(4) Put the Ag-rGO filter paper in step (3) into the pressing groove of the hot press so that Ag-rGO and the filter paper can be better compounded, and the Ag-rGO filter paper after hot pressing Cut to an ideal shape after drying, glue copper wires to both ends of the Ag-rGO filter paper cut to the desired shape with silver glue and put it in an oven to dry, and finally put the surface of the dried Ag-rGO filter paper on the surface A layer of PDMS was applied and dried in an oven to obtain an Ag-rGO filter paper flexible sensor.

(5) A double-sided tape or other viscous substance is attached to one side of the Ag-rGO filter paper flexible sensor to make it adhere to the surface of the detection object.

Preferably, the AgNWS aqueous solution concentration in step (1) is 4-10 mg/ml.

Preferably, the mass ratio of the ascorbic acid (AA) in the step (1) to the graphene oxide in the graphene oxide solution is 3:1.

Preferably, the concentration of the graphene oxide solution in step (1) is 2-10 mg/ml.

Preferably, in step (1), the mass ratio of AgNWS in the AgNWS aqueous solution to the graphene oxide in the graphene oxide aqueous solution is 1-2.5.

Preferably, in step (2), the reaction setting temperature of the oven is 120°C-140°C, and the time is 3-5h.

Preferably, in step (3), the ultrasonic pulverization interval is 3:2, the period is 30s, and the cycle is 90 times.

Preferably, in step (2), the rotating speed of the centrifuge is 5000-8000 rad/min, and the time is 5-10 min.

Preferably, the temperature of the hot press in step (4) is 130-180°C, and the time is 700-1000s.

Preferably, in step (4), the oven temperature is 110-130° C. until it is dry.

beneficial effect

Compared with the prior art, the advantages of the present invention are:

1. Composite AgNWS and graphene oxide, improve the conductivity of reduced graphene oxide through AgNWS, change the contact mode between the reduced graphene oxide sheets, increase the conduction path, thereby improving the sensitivity of the sensor, Ag-rGO filter paper is flexible The sensor has a wide range of applications and has the ability to detect strain; it has high sensitivity; it can still maintain good performance after repeated fatigue tests. In the lip movement test, the ability to realize lip language recognition;

2. The reaction adopts a one-step solvent hydrothermal method to prepare the Ag-rGO composite solution and directly filter it on the filter paper. The filter paper is used as the carrier. The operation is simple, the cost is low, the success rate is extremely high, the yield is stable, and the purity is high. The obtained material The morphology and structure are controllable, which is convenient for mass production;

3. A polydimethylsiloxane (PDMS) film with micro-cylindrical arrays was drop-coated on the Ag-rGO filter paper. After drying, the Ag-rGO filter paper films were embedded with each other to construct a flexible interlocking structure sensor. It responds to stretching, pressure, bending, and shearing forces, and can distinguish human motion. Compared with double-layer planar sensors and single-layer micro-pillar array sensors, it can achieve more detailed multi-peak detection, which is useful for future medical diagnosis and health. Monitoring is important.

4. The hot-pressing process is adopted, and the Ag-rGO film and filter paper can be better combined after hot-pressing, so that Ag is embedded in the filter paper, and the weak current generated when the Ag-rGO filter paper flexible sensor works makes Ag into a free state. , Ag ions have antibacterial effect and it has been verified that the antibacterial effect of Ag and rGO combination is better;

5. Double-sided tape or any sticky substance can be pasted on one side of the filter paper, so that the flexible sensor of Ag-rGO filter paper can be applied to different scenarios.

Description of drawings

Fig. 1 is the electron microscope picture of filter paper after suction filtration in the present invention;

Figure 2 is a schematic structural diagram of the Ag-rGO filter paper flexible sensor in the present invention;

Figure 3 is a cross-sectional view of the Ag-rGO filter paper flexible sensor in the present invention.

reference number

PDMS 1, filter paper 2, Ag-rGO 3, double-sided tape or other sticky substances 4.

Detailed ways

In order to better illustrate and describe the content of the present invention, the following description will be carried out in conjunction with the accompanying drawings and implementation examples:

As shown in Figures 1-3, the present invention discloses a preparation method of a filter paper-based flexible sensor with antibacterial function, comprising the following steps:

(1) Ag-rGO composite solution is prepared by one-step solvent hydrothermal method: graphene oxide solution and AgNWS aqueous solution are prepared, ascorbic acid (AA) and graphene oxide solution are mixed and stirred evenly and then added to the AgNWS aqueous solution to obtain a mixed solution;

(2) the described mixed solution in the step (1) is transferred in the polytetrafluoroethylene reactor and put into the baking oven, after the reaction finishes at the set temperature and time, obtain the black mixed solution, use deionized water and The black mixed solution was centrifuged and washed with absolute ethanol for several times to remove impurities to obtain an Ag-rGO solution;

(3) ultrasonically pulverizing the Ag-rGO solution in step (2) to obtain an Ag-rGO composite solution uniformly dispersed in deionized water, and dropping the Ag-rGO composite solution uniformly dispersed in deionized water onto filter paper 2. The filter paper 2 is then filtered and dried to obtain Ag-rGO filter paper;

(4) Put the Ag-rGO filter paper in step (3) into the pressing groove of the hot press so that Ag-rGO 3 and the filter paper 2 can be better compounded, and the Ag-rGO after hot pressing After drying, the rGO filter paper was cut to the desired shape, and the copper wire was glued to both ends of the Ag-rGO filter paper cut to the desired shape with silver glue and placed in an oven to dry. Finally, the Ag-rGO filter paper after drying was dried. A layer of PDMS 1 was applied to the surface of the surface, and then dried in an oven to obtain an Ag-rGO filter paper flexible sensor.

(5) A double-sided tape or other adhesive substance 4 is attached to one side of the Ag-rGO filter paper flexible sensor to make it adhere to the surface of the detection object.

Preferably, the AgNWS aqueous solution concentration in step (1) is 4-10 mg/ml.

Preferably, the mass ratio of the ascorbic acid (AA) in the step (1) to the graphene oxide in the graphene oxide solution is 3:1.

Preferably, the concentration of the graphene oxide solution in step (1) is 2-10 mg/ml.

Preferably, in step (1), the mass ratio of AgNWS in the AgNWS aqueous solution to the graphene oxide in the graphene oxide aqueous solution is 1-2.5.

Preferably, in step (2), the reaction setting temperature of the oven is 120°C-140°C, and the time is 3-5h.

Preferably, in step (3), the ultrasonic pulverization interval is 3:2, the period is 30s, and the cycle is 90 times.

Preferably, in step (2), the rotating speed of the centrifuge is 5000-8000 rad/min, and the time is 5-10 min.

Preferably, the temperature of the hot press in step (4) is 130-180°C, and the time is 700-1000s.

Preferably, in step (4), the oven temperature is 110-130° C. until it is dry.

Specifically, prepare graphene oxide solution 2mg/ml and AgNWS aqueous solution 4mg/ml, mix and stir 54mg ascorbic acid (AA) and 10ml graphene oxide solution and add to the AgNWS aqueous solution (4mg/ml 5ml) to obtain a mixed solution, the The mixed solution was transferred to a polytetrafluoroethylene reactor and placed in an oven for 4 hours at 120°C. After the reaction, a black mixed solution was obtained. The black mixed solution was centrifuged and washed several times with deionized water and absolute ethanol to remove impurities to obtain Ag. -rGO3, the rotation speed is 5000rad/min, the time is 5min, the solution after centrifugal washing is ultrasonically pulverized to obtain the Ag-rGO composite solution uniformly dispersed in deionized water, and it is suction filtered on filter paper 2, and transferred to a hot press at 130 ° C After 800s, the dry Ag-rGO filter paper is obtained. Cut the dry Ag-rGO filter paper to the desired desired shape and glue the copper wire to both ends with silver glue. Finally, apply a layer of PDMS 1 on its surface and put it in the oven , at 120 °C until it is dry, an Ag-rGO filter paper flexible sensor is obtained. When using, double-sided tape can be pasted on the filter paper surface of the Ag-rGO filter paper flexible sensor to adapt to the attachment of various parts of the human body.

Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, but not to limit them; although the technical solutions of the present invention have been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that they are still Modifications can be made to the technical solutions described in the foregoing embodiments, or some technical features thereof can be equivalently replaced; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims (10)

1. the preparation method of the flexible sensor that a filter paper base has antibacterial function, is characterized in that, comprises the steps: (1) Ag-rGO composite solution is prepared by one-step solvent hydrothermal method: graphene oxide solution and AgNWS aqueous solution are prepared, ascorbic acid (AA) and graphene oxide solution are mixed and stirred evenly and then added to the AgNWS aqueous solution to obtain a mixed solution; (2) the described mixed solution in the step (1) is transferred in the polytetrafluoroethylene reactor and put into the baking oven, after the reaction finishes at the set temperature and time, obtain the black mixed solution, use deionized water and The black mixed solution was centrifuged and washed with absolute ethanol for several times to remove impurities to obtain an Ag-rGO solution; (3) ultrasonically pulverizing the Ag-rGO solution in step (2) to obtain an Ag-rGO composite solution uniformly dispersed in deionized water, and dropping the Ag-rGO composite solution uniformly dispersed in deionized water onto filter paper (2), then the filter paper (2) is filtered and dried to obtain Ag-rGO filter paper; (4) Put the Ag-rGO filter paper in step (3) into the pressing groove of the hot press so that the Ag-rGO (3) and the filter paper (2) can be better compounded. The Ag-rGO filter paper is dried and cut to an ideal shape, and the copper wire is glued to both ends of the Ag-rGO filter paper cut to the desired shape with silver glue, and then placed in an oven to dry. The surface of Ag-rGO filter paper was coated with a layer of PDMS (1), and then dried in an oven to obtain a flexible sensor of Ag-rGO filter paper. (5) A double-sided tape or other sticky substance is attached to one side of the Ag-rGO filter paper flexible sensor (4) to make it adhere to the surface of the detection object. 2 . The preparation method of a filter paper-based flexible sensor with antibacterial function according to claim 1 , wherein the AgNWS aqueous solution in step (1) has a concentration of 4-10 mg/ml. 3 . 3. the preparation method of the flexible sensor with antibacterial function of a kind of filter paper base according to claim 1, is characterized in that, described ascorbic acid (AA) in step (1) and the graphite oxide in described graphene oxide solution The mass ratio of ene is 3:1. 4. The preparation method of a filter paper-based flexible sensor with antibacterial function according to claim 1, wherein the concentration of the graphene oxide solution in step (1) is 2-10 mg/ml. 5. the preparation method of the flexible sensor with antibacterial function of a kind of filter paper base according to claim 1, is characterized in that, the AgNWS in the described AgNWS aqueous solution in the step (1) and the oxidation in the described graphene oxide aqueous solution The mass ratio of graphene is 1-2.5. 6. The preparation method of a filter paper-based flexible sensor with antibacterial function according to claim 1, characterized in that in step (2), the reaction setting temperature in the oven is 120°C-140°C, and the time is 3-5h . 7 . The method for preparing a filter paper-based flexible sensor with antibacterial function according to claim 1 , wherein in step (3), the ultrasonic pulverization interval is 3:2, the cycle is 30s, and the cycle is 90 times. 8 . 8 . The preparation method of a filter paper-based flexible sensor with antibacterial function according to claim 1 , wherein in step (2), the rotating speed of the centrifuge is 5000-8000 rad/min, and the time is 5-10 min. 9 . 9 . The preparation method of a filter paper-based flexible sensor with antibacterial function according to claim 1 , wherein in step (4), the temperature of the hot press is 130-180° C. and the time is 700-1000 s. 10 . 10 . The preparation method of a filter paper-based flexible sensor with antibacterial function according to claim 1 , wherein in step (4), the oven temperature is 110-130° C. until it is dry. 11 .

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