CN114405069B - A PRP extraction device and implementation method thereof - Google Patents
A PRP extraction device and implementation method thereof Download PDFInfo
- Publication number
- CN114405069B CN114405069B CN202210104859.1A CN202210104859A CN114405069B CN 114405069 B CN114405069 B CN 114405069B CN 202210104859 A CN202210104859 A CN 202210104859A CN 114405069 B CN114405069 B CN 114405069B
- Authority
- CN
- China
- Prior art keywords
- extraction
- connector
- prp
- extraction tube
- tube
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000605 extraction Methods 0.000 title claims abstract description 81
- 238000000034 method Methods 0.000 title claims abstract description 12
- 210000004369 blood Anatomy 0.000 claims abstract description 22
- 239000008280 blood Substances 0.000 claims abstract description 22
- 238000005119 centrifugation Methods 0.000 claims abstract description 13
- 239000007788 liquid Substances 0.000 claims description 13
- 238000005086 pumping Methods 0.000 claims description 13
- 210000000265 leukocyte Anatomy 0.000 abstract description 6
- 210000004623 platelet-rich plasma Anatomy 0.000 abstract description 6
- 102000009123 Fibrin Human genes 0.000 abstract description 4
- 108010073385 Fibrin Proteins 0.000 abstract description 4
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 abstract description 4
- 229950003499 fibrin Drugs 0.000 abstract description 4
- 239000000284 extract Substances 0.000 abstract 1
- 210000002381 plasma Anatomy 0.000 description 6
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 239000003102 growth factor Substances 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 210000000130 stem cell Anatomy 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
- B01D17/02—Separation of non-miscible liquids
- B01D17/0217—Separation of non-miscible liquids by centrifugal force
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
- B01D17/12—Auxiliary equipment particularly adapted for use with liquid-separating apparatus, e.g. control circuits
Landscapes
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- External Artificial Organs (AREA)
Abstract
本发明公开了一种PRP提取装置，包括提取管，提取管的上端设有连接头，提取管的内部设有活塞；本发明还公开了一种PRP提取装置的实现方法。本发明通过提取管对PRP进行提取，无需用长针管伸入进行提取，减少了人为因素的干扰，所提取PRP的纯度更高，更加稳定，从而可以提取富白细胞富白小板血浆、贫白细胞富血小板血浆和可注射型富血小板纤维蛋白；本发明连接头上套设有端盖，通过端盖密封连接头，从而避免在离心时，血液从连接头处甩出；本发明提取管的底部设有底座，通过底座对活塞进行限位，从而可以避免提取管在离心的过程中导致活塞被甩出。
The present invention discloses a PRP extraction device, including an extraction tube, a connector is provided at the upper end of the extraction tube, and a piston is provided inside the extraction tube; the present invention also discloses a method for realizing the PRP extraction device. The present invention extracts PRP through the extraction tube, and does not need to use a long needle tube to insert for extraction, thereby reducing the interference of human factors, and the extracted PRP has higher purity and is more stable, so that leukocyte-rich platelet-rich plasma, leukocyte-poor platelet-rich plasma and injectable platelet-rich fibrin can be extracted; the connector of the present invention is provided with an end cap, and the connector is sealed by the end cap, so as to avoid blood being thrown out from the connector during centrifugation; the bottom of the extraction tube of the present invention is provided with a base, and the piston is limited by the base, so as to avoid the piston being thrown out during the centrifugation of the extraction tube.
Description
Technical Field
The invention belongs to the technical field of PRP extraction, and particularly relates to a PRP extraction device and an implementation method thereof.
Background
PRP autologous serum stem cells (PLATELET RICH PLASMA) refer to platelet-rich, plasma-rich or growth factor-rich blood cells. PRP extraction refers to the extraction of cells and plasma rich in high concentrations of platelets and various self-growth factors from their own blood.
In the prior art, most of blood is collected through a blood collection tube, then the blood in the blood collection tube is centrifuged by using a centrifuge, and then the blood is inserted into a centrifuged test tube liquid by using a long needle tube (from top to bottom), and because PRP autologous serum stem cells generally exist in an intermediate layer and are extracted by hand, the technical defects of large error, poor repeatability, large interference of human factors, unstable concentration, poor effect and the like exist.
Disclosure of Invention
The present invention is directed to a PRP extraction device, which solves the problems set forth in the background art. The PRP extraction device provided by the invention has the characteristic of being capable of accurately extracting PRP.
The invention further aims at providing a method for realizing the PRP extraction device.
In order to achieve the purpose, the PRP extracting device comprises an extracting pipe, wherein a connector is arranged at the upper end of the extracting pipe, and a piston is arranged in the extracting pipe.
In order to seal the connector and thereby avoid that blood is thrown out from the connector 5 during centrifugation, further, the connector is sleeved with an end cover.
In order to facilitate the disassembly and assembly between the end cover and the connector, the end cover is further connected with the connector through threaded engagement.
In order to facilitate the disassembly and assembly between the end cover and the connector, further, the connector is of a frustum-shaped structure, the structure of the end cover corresponds to that of the connector, and the end cover is connected with the connector through interference fit.
In order to avoid the piston being thrown out in the centrifuging process of the extraction tube, a base is arranged at the bottom of the extraction tube.
In order to facilitate the assembly of the piston and the extraction tube, further, the base is connected with the extraction tube by threaded engagement.
In order to facilitate the movement of the piston in the extraction tube during the injection or withdrawal of blood, the lower end of the extraction tube is further provided with air holes near the base.
In order to extract PRP more stably and ensure the accuracy of extraction, the device further comprises an elbow which is arranged above the connector.
In the invention, the implementation method of the PRP extraction device comprises the following steps:
firstly, injecting blood into an extraction tube through a connector;
covering an end cover, and putting the extraction pipe into a centrifugal machine for centrifugation;
thirdly, after centrifugation, opening the end cover, connecting the extraction needle cylinder with the connector through an elbow, and extracting PP and PRP liquid at the upper layer in the extraction tube;
(IV) injecting the extracted PP and PRP liquids into a new extraction tube;
fifth, repeating the second step;
and sixthly, pumping the PP liquid at the upper layer through a pumping needle cylinder, and pumping the residual PRP liquid in the pumping tube through a new pumping needle cylinder.
Compared with the prior art, the invention has the beneficial effects that:
1. According to the invention, the PRP is extracted through the extraction tube, and the long needle tube is not required to extend into the extraction tube for extraction, so that the interference of human factors is reduced, the purity of the extracted PRP is higher and more stable, and thus the white blood cell-rich and white blood cell-rich plasma, the white blood cell-poor and platelet-rich plasma and the injectable platelet-rich fibrin can be extracted;
2. The end cover is sleeved on the connector, and the connector is sealed by the end cover, so that blood is prevented from being thrown out from the connector during centrifugation;
3. the bottom of the extraction tube is provided with the base, and the piston is limited by the base, so that the piston is prevented from being thrown out in the process of centrifuging the extraction tube;
4. The circumference of the lower end of the extraction tube is provided with the air holes close to the base, so that the piston can move in the extraction tube when blood is injected or extracted.
Drawings
FIG. 1 is a schematic diagram of the structure of the present invention;
FIG. 2 is a schematic cross-sectional view of the present invention;
FIG. 3 is a schematic representation of the use of the present invention;
FIG. 4 is a schematic cross-sectional view of embodiment 2 of the present invention;
In the figure, 1, a base, 2, a piston, 3, an extraction pipe, 4, an end cover, 5, a connector, 6, an air hole, 7, an elbow and 8, and an extraction needle cylinder.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1
Referring to fig. 1-3, the present invention provides a PRP extraction device, which comprises an extraction tube 3, wherein a connector 5 is arranged at the upper end of the extraction tube 3, and a piston 2 is arranged inside the extraction tube 3.
By adopting the technical scheme, the PRP is extracted through the extraction tube 3, the long needle tube is not required to extend into the extraction tube for extraction, the interference of human factors is reduced, the purity of the extracted PRP is higher and more stable, and therefore, the white blood cell-rich and white platelet-rich plasma (L-PRP), the white blood cell-poor and platelet-rich plasma (P-PRP) and the injectable platelet-rich fibrin (i-PRF) can be extracted.
Specifically, an end cover 4 is sleeved on the connector 5.
Through adopting above-mentioned technical scheme, through end cover 4 sealing connection head 5 to avoid when centrifuging, the blood throws away from connector 5.
Specifically, the end cap 4 is connected with the connector 5 through threaded engagement.
By adopting the technical scheme, the disassembly and assembly between the end cover 4 and the connector 5 are convenient.
Specifically, the bottom of extraction tube 3 is equipped with base 1.
Through adopting above-mentioned technical scheme, carry out spacingly through base 1 to piston 2 to can avoid extracting pipe 3 to lead to piston 2 to be thrown away at centrifugal in-process.
Specifically, the base 1 is connected with the extraction tube 3 by screw engagement.
By adopting the technical scheme, the base 1 and the extraction pipe 3 are convenient to assemble and disassemble, and therefore the piston 2 and the extraction pipe 3 are convenient to assemble.
Specifically, the circumference of the lower end of the extraction tube 3 is provided with air holes 6 close to the base 1.
By adopting the above-described solution, the movement of the piston 2 inside the extraction tube 3 during the injection or extraction of blood is facilitated.
Example 2
Referring to fig. 4, the difference between the present embodiment and embodiment 1 is that, specifically, the connector 5 has a frustum-shaped structure, the structure of the end cover 4 corresponds to that of the connector 5, and the end cover 4 and the connector 5 are connected by interference fit.
By adopting the technical scheme, the disassembly and assembly between the end cover 4 and the connector 5 are convenient.
Example 3
The embodiment is different from the embodiment 1 in that the connector further comprises an elbow 7, and the elbow 7 is arranged above the connector.
Through adopting above-mentioned technical scheme, make through setting up of elbow 7 can the level operate when extracting PRP through extraction cylinder 8 to can more steadily draw PRP, ensure the accuracy of extraction.
Further, the implementation method of the PRP extraction device provided by the invention comprises the following steps:
Firstly, injecting blood into the extraction tube 3 through the connector 5;
secondly, covering the end cover 4, and putting the extraction tube 3 into a centrifugal machine for centrifugation;
Thirdly, after centrifugation, opening the end cover 4, connecting the extraction needle cylinder 8 with the connector 5 through the elbow 7, and extracting PP (plasma) and PRP liquid at the upper layer in the extraction tube 3;
(IV), injecting the extracted PP and PRP liquid into a new extraction pipe 3;
fifth, repeating the second step;
Sixth, the upper layer of PP liquid is pumped out by the pumping syringe 8, and the remaining PRP liquid in the pumping tube 3 is pumped out by the new pumping syringe 8.
In summary, the PRP is extracted through the extracting tube 3, the long needle tube is not required to extend into the extracting tube for extraction, the interference of human factors is reduced, the purity of the extracted PRP is higher and more stable, so that the white blood cell-rich platelet plasma (L-PRP), the white blood cell-rich platelet plasma (P-PRP) and the injectable platelet-rich fibrin (i-PRF) can be extracted, the end cover 4 is sleeved on the connecting head 5, the connecting head 5 is sealed through the end cover 4, so that blood is prevented from being thrown out from the connecting head 5 during centrifugation, the base 1 is arranged at the bottom of the extracting tube 3, the piston 2 is limited through the base 1, the piston 2 is prevented from being thrown out during centrifugation, and the air holes 6 close to the base 1 are formed in the circumference of the lower end of the extracting tube 3, so that the piston 2 can move in the extracting tube 3 during blood injection or extraction.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (4)
1. A PRP extraction device comprises an extraction tube and is characterized in that a connector is arranged at the upper end of the extraction tube, a piston is arranged in the extraction tube, a base is arranged at the bottom of the extraction tube, and air holes close to the base are formed in the circumference of the lower end of the extraction tube;
an end cover is sleeved on the connecting head;
The connector is of a frustum-shaped structure, the structure of the end cover corresponds to that of the connector, and the end cover is connected with the connector through interference fit;
The elbow is arranged above the connector;
The connector is sealed through the end cover, so that blood is prevented from being thrown out from the connector during centrifugation;
the piston is limited through the base, so that the piston is prevented from being thrown out in the centrifuging process of the extraction pipe;
The circumference of the lower end of the extraction tube is provided with air holes close to the base, so that the piston can move in the extraction tube when blood is injected or extracted;
The PRP can be horizontally extracted through the arrangement of the elbow, so that the PRP can be extracted more stably, and the extracting accuracy is ensured.
2. The PRP extracting device of claim 1, wherein the end cap is threadably engaged with the connector.
3.A PRP extraction device according to claim 1, wherein the base is threadably engaged with the extraction tube.
4. A method of implementing a PRP extraction apparatus according to any one of claims 1 to 3, comprising the steps of:
firstly, injecting blood into an extraction tube through a connector;
covering an end cover, and putting the extraction pipe into a centrifugal machine for centrifugation;
thirdly, after centrifugation, opening the end cover, connecting the extraction needle cylinder with the connector through an elbow, and extracting PP and PRP liquid at the upper layer in the extraction tube;
(IV) injecting the extracted PP and PRP liquids into a new extraction tube;
fifth, repeating the second step;
and sixthly, pumping the PP liquid at the upper layer through a pumping needle cylinder, and pumping the residual PRP liquid in the pumping tube through a new pumping needle cylinder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210104859.1A CN114405069B (en) | 2022-01-28 | 2022-01-28 | A PRP extraction device and implementation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210104859.1A CN114405069B (en) | 2022-01-28 | 2022-01-28 | A PRP extraction device and implementation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114405069A CN114405069A (en) | 2022-04-29 |
| CN114405069B true CN114405069B (en) | 2025-03-25 |
Family
ID=81279605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210104859.1A Active CN114405069B (en) | 2022-01-28 | 2022-01-28 | A PRP extraction device and implementation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114405069B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116212451B (en) * | 2023-03-17 | 2025-05-09 | 中国人民解放军联勤保障部队第九二〇医院 | A PRP multilayer separation and extraction test tube |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104548232A (en) * | 2013-10-15 | 2015-04-29 | 金鸿 | Device and method of extracting high-concentration plasma from whole blood |
| CN110433969A (en) * | 2018-05-04 | 2019-11-12 | 百泽生医科技股份有限公司 | Liquid separating appts and its application method |
| CN217340180U (en) * | 2022-01-28 | 2022-09-02 | 广东汉鼎医疗科技有限公司 | PRP extraction element |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102078644A (en) * | 2011-03-08 | 2011-06-01 | 吉林大学 | Simple, convenient and efficient device and method for extracting platelet-rich plasma |
| CN106076448A (en) * | 2016-07-27 | 2016-11-09 | 上海凯戎医疗科技有限公司 | A kind of piston-type medical centrifugal and for preparing the preparation method of platelet rich plasma |
| CN207412824U (en) * | 2017-10-27 | 2018-05-29 | 广州派俪生物科技有限公司 | A kind of blood separation of high efficiency extraction Platelet Concentrate and extraction element |
| TWI687240B (en) * | 2018-09-13 | 2020-03-11 | 美康生物科技有限公司 | Blood collection device and method for manufacturing high concentration platelet plasma |
-
2022
- 2022-01-28 CN CN202210104859.1A patent/CN114405069B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104548232A (en) * | 2013-10-15 | 2015-04-29 | 金鸿 | Device and method of extracting high-concentration plasma from whole blood |
| CN110433969A (en) * | 2018-05-04 | 2019-11-12 | 百泽生医科技股份有限公司 | Liquid separating appts and its application method |
| CN217340180U (en) * | 2022-01-28 | 2022-09-02 | 广东汉鼎医疗科技有限公司 | PRP extraction element |
Also Published As
| Publication number | Publication date |
|---|---|
| CN114405069A (en) | 2022-04-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103566629B (en) | Method and device for separating and extracting platelet rich blood | |
| CN104704106B (en) | Extract from hematoblastic blood separation container | |
| CN106669875B (en) | Platelet-rich plasma centrifuge tube and extraction method thereof | |
| CN105596014B (en) | A kind of double-jacket tube centrifugation injection device | |
| CN114405069B (en) | A PRP extraction device and implementation method thereof | |
| RU184978U1 (en) | Platelet-rich syringe for platelet rich plasma | |
| CN114160226A (en) | Centrifugal separation tube and manufacturing method and application thereof | |
| CN203648142U (en) | Blood platelet-rich separation and extraction device | |
| CN217340180U (en) | PRP extraction element | |
| CN203953668U (en) | blood separation device | |
| CN218486261U (en) | Aseptic PRP extraction element | |
| CN218167377U (en) | PRP preparation facilities | |
| CN211570632U (en) | Stem cell extraction element | |
| CN112934287A (en) | Centrifugal tube and PRP extraction method using same | |
| KR20130005456A (en) | Injection syringe for separating platelet rich plasma | |
| CN221471876U (en) | Integrated centrifuge tube for preparing platelet-rich plasma | |
| CN221999460U (en) | Platelet-rich plasma separation device | |
| CN210159636U (en) | A centrifuging tube structure for lipemia sample is handled | |
| CN218107713U (en) | Platelet-rich plasma preparation device | |
| CN206706092U (en) | A kind of centrifuge tube | |
| KR102741742B1 (en) | Kit for Separating Blood | |
| CN222778232U (en) | Device for gradient centrifugation of liquid in cooperation with centrifugal machine | |
| CN216395349U (en) | Multistage blood separation device | |
| CN219023345U (en) | PRP extraction element that avoids remaining | |
| CN219043331U (en) | Centrifuging tube convenient to draw platelet rich plasma |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |