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CN114376541A - Device and method for monitoring human vital signs - Google Patents

Device and method for monitoring human vital signs Download PDF

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CN114376541A
CN114376541A CN202111667073.2A CN202111667073A CN114376541A CN 114376541 A CN114376541 A CN 114376541A CN 202111667073 A CN202111667073 A CN 202111667073A CN 114376541 A CN114376541 A CN 114376541A
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heart sound
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徐屹
余善恩
孔亚广
童啸龙
黄朱辉
陈建科
孙莹伊
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Hangzhou Dianzi University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/0205Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • A61B5/02055Simultaneously evaluating both cardiovascular condition and temperature
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    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
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    • H04W76/00Connection management
    • H04W76/10Connection setup
    • H04W76/14Direct-mode setup
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
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Abstract

The invention discloses a human body vital sign monitoring device and a method, wherein a central module comprises a first NRF52832 Bluetooth minimum system board, a PPG module, a body temperature module and a storage module; human PPG signal is gathered to the PPG module, human body surface temperature signal is gathered to the body temperature module, human chest heart sound signal is gathered to first heart sound module, the heart sound signal of wrist is gathered to wrist heart sound module, each vital sign signal that storage module will gather stores, the minimum system board of first NRF52832 bluetooth reads the PPG module, the signal and the data of body temperature module and first heart sound module, control write in data and send data to the host computer through BLE4.2 agreement in to storage module. According to the invention, the relevant characteristic value is obtained by combining the heart sound signal and the PPG signal and then is introduced into the blood pressure prediction model, so that the blood pressure value of the human body can be accurately obtained in real time, and meanwhile, the system can be conveniently connected to modern mobile phones, tablets and other upper computers by adopting a BLE4.2 protocol so as to realize better universality of the system.

Description

一种人体生命体征监测装置和方法Device and method for monitoring human vital signs

技术领域technical field

本发明属于医疗传感器无线自组网数据采集领域,特别涉及一种人体生命体征监测装置和方法。The invention belongs to the field of medical sensor wireless ad hoc network data collection, and particularly relates to a human vital sign monitoring device and method.

背景技术Background technique

蓝牙技术在医疗领域的应用,能极大的方便居民身体健康状态的监测,而通过使用蓝牙的MESH组网技术通过采集人体不同部位的生命体征可以更加准确的反映人体的健康状态,这在便利居民就医以及缓解社会医疗压力方面起到了至关重要的作用。The application of Bluetooth technology in the medical field can greatly facilitate the monitoring of the health status of residents. By using the MESH networking technology of Bluetooth, the health status of the human body can be more accurately reflected by collecting the vital signs of different parts of the human body, which is convenient and convenient. It has played a vital role in residents seeking medical treatment and alleviating social medical pressure.

当前相关产品存在以下问题:The current related products have the following problems:

(1)设备往往只能监测心率,温度等基础的生命体征不能够全面的反映人体健康状态。(1) The equipment can only monitor the basic vital signs such as heart rate and temperature, which cannot fully reflect the health status of the human body.

(2)大部分使用蓝牙技术的设备往往以手环的形式只佩戴在手腕上,这使得对血压,心输出量这一类数据的测量存在较大的误差。(2) Most of the devices using Bluetooth technology are often only worn on the wrist in the form of a bracelet, which makes the measurement of blood pressure, cardiac output and other data have large errors.

(3)传统的血压测量设备往往只能对一段时间内的血压信号进行测量,不能实现对血压信号的连续监测。(3) The traditional blood pressure measurement equipment can only measure the blood pressure signal within a period of time, and cannot realize the continuous monitoring of the blood pressure signal.

(4)当前设备使用光电容积脉搏波的血压预测方法复杂度过高,难以在低功耗,低速率的设备上实现。为解决传统生命体征监测设备的测量信号种类不全, 且对手腕部位血压信号检测的不准确,不能监测连续的血压信号,血压预测算法复杂度过高的问题,开发一款解决上述痛点的人体生命体征监测系统十分必要。(4) The current device's blood pressure prediction method using photoplethysmography is too complicated and difficult to implement on low-power and low-speed devices. In order to solve the problems of incomplete measurement signals of traditional vital signs monitoring equipment, inaccurate detection of blood pressure signals at the wrist, inability to monitor continuous blood pressure signals, and high complexity of blood pressure prediction algorithms, we developed a human life solution that solves the above pain points. A sign monitoring system is necessary.

发明内容SUMMARY OF THE INVENTION

有鉴于此,本发明提供了一种人体生命体征监测装置,包括中心模块、第一心音模块和腕部心音模块,第一心音模块和腕部心音模块均与中心模块连接,其中,In view of this, the present invention provides a human vital sign monitoring device, including a center module, a first heart sound module and a wrist heart sound module, wherein the first heart sound module and the wrist heart sound module are both connected to the center module, wherein,

所述中心模块包括第一NRF52832蓝牙最小系统板、PPG模块、体温模块和存储模块;PPG模块、体温模块和存储模块均与第一NRF52832蓝牙最小系统板连接,PPG模块采集人体PPG信号,体温模块采集人体体表温度信号,第一心音模块采集人体胸前心音信号,腕部心音模块采集腕部的心音信号,存储模块将采集到的各生命体征信号进行存储,第一NRF52832蓝牙最小系统板读取PPG模块、体温模块和第一心音模块的信号及数据,控制向存储模块中写入数据并且通过BLE4.2协议向上位机发送数据;The central module includes the first NRF52832 Bluetooth minimum system board, a PPG module, a body temperature module and a storage module; the PPG module, the body temperature module and the storage module are all connected to the first NRF52832 Bluetooth minimum system board, the PPG module collects human PPG signals, and the body temperature module Collect the body surface temperature signal, the first heart sound module collects the human chest heart sound signal, the wrist heart sound module collects the wrist heart sound signal, and the storage module stores the collected vital signs signals. The first NRF52832 Bluetooth minimum system board Read the signals and data of the PPG module, the body temperature module and the first heart sound module, control to write data into the storage module and send data to the upper computer through the BLE4.2 protocol;

所述第一心音模块包括依次连接的PVDF传感器、模数信号转换器和信号滤波及放大电路,其中,PVDF传感器采集人体的心音信息并转换为电压信号,信号滤波及放大电路对PVDF传感器产生的电信号进行滤波处理降低噪声对心音信号的干扰并对信号进行放大,模数信号转换器接收信号滤波及放大电路处理过后的电信号并转换为数字信号输出给中心模块。The first heart sound module includes a PVDF sensor, an analog-to-digital signal converter, and a signal filtering and amplifying circuit that are connected in sequence, wherein the PVDF sensor collects the heart sound information of the human body and converts it into a voltage signal, and the signal filtering and amplifying circuit generates the PVDF sensor. The electrical signal is filtered and processed to reduce the interference of noise on the heart sound signal and the signal is amplified. The analog-to-digital signal converter receives the electrical signal processed by the signal filtering and amplifying circuit, converts it into a digital signal and outputs it to the central module.

优选地,所述腕部心音模块包括相连接的第二NRF52832蓝牙最小系统板和第二心音模块,第二心音模块采集腕部的心音信号,第二NRF52832蓝牙最小系统板接收第二心音模块采集的数据并向中心模块发送。Preferably, the wrist heart sound module includes a connected second NRF52832 Bluetooth minimum system board and a second heart sound module, the second heart sound module collects the wrist heart sound signal, and the second NRF52832 Bluetooth minimum system board receives the second heart sound module collection data and send it to the central module.

优选地,所述PPG模块包括MAX30100脉搏血氧和心率检测传感器。Preferably, the PPG module includes a MAX30100 pulse oximetry and heart rate detection sensor.

优选地,所述体温模块包括CJMCU30205人体温传感器。Preferably, the body temperature module includes a CJMCU30205 human body temperature sensor.

优选地,所述存储模块包括W25Q16存储器。Preferably, the memory module includes W25Q16 memory.

基于上述目的,本发明还提供了一种人体生命体征监测方法,采用上述装置,包括以下步骤:Based on the above purpose, the present invention also provides a method for monitoring human vital signs, using the above device, comprising the following steps:

S1,中心模块布置在人体胸前,上电后第一NRF52832蓝牙最小系统板设置基本蓝牙广播模式让其它蓝牙设备可以发现并且建立连接,由上位机将中心模块配置为MESH网络中的节点,并且初始化各种蓝牙服务;S1, the center module is arranged on the chest of the human body. After power-on, the first NRF52832 Bluetooth minimum system board sets the basic Bluetooth broadcast mode so that other Bluetooth devices can discover and establish connections. The host computer configures the center module as a node in the MESH network, and Initialize various Bluetooth services;

S2,创建定时器任务来定时采集PPG模块、体温模块和第一心音模块的数据,并存入存储模块;S2, create a timer task to periodically collect the data of the PPG module, the body temperature module and the first heart sound module, and store them in the storage module;

S3,接收腕部心音模块传输的腕部心音后,通过血压预测模型得到实时的血压信号,将所有的生命体征打包通过蓝牙服务向主机发送数据包;S3, after receiving the wrist heart sound transmitted by the wrist heart sound module, obtain the real-time blood pressure signal through the blood pressure prediction model, package all vital signs and send data packets to the host through the Bluetooth service;

S4,接收上位机的返回数据验证是否数据传输正常,若发生丢包或数据错误则重新发送数据包。S4: Receive the returned data from the host computer to verify whether the data transmission is normal, and resend the data packet if packet loss or data error occurs.

优选地,所述S2具体包括以下步骤:Preferably, the S2 specifically includes the following steps:

S21,第一心音模块在上电后由中心模块进行初始化;S21, the first heart sound module is initialized by the central module after being powered on;

S22,PVDF传感器采集人体的心音信号,采集到的信号通过信号滤波及放大电路处理过后滤除工频噪声以及环境噪声,并将信号幅值放大到2.0V到3.3V 区间;S22, the PVDF sensor collects the heart sound signal of the human body, and the collected signal is processed by the signal filtering and amplifying circuit to filter out the power frequency noise and environmental noise, and amplify the signal amplitude to the range of 2.0V to 3.3V;

S23,由模数信号转换器将放大后的信号转换为数字信号等待中心模块的采集。S23 , the amplified signal is converted into a digital signal by an analog-to-digital signal converter and waits for collection by the central module.

优选地,所述S3具体包括以下步骤:Preferably, the S3 specifically includes the following steps:

S31,腕部心音模块布置在手腕处,在上电后第二NRF52832蓝牙最小系统板设置基本蓝牙广播模式让其它蓝牙设备可以发现并且建立连接,由上位机将腕部心音模块配置为MESH网络中的节点,并初始化各种蓝牙服务;S31, the wrist heart sound module is arranged at the wrist. After power-on, the second NRF52832 Bluetooth minimum system board sets the basic Bluetooth broadcast mode so that other Bluetooth devices can discover and establish connections. The upper computer configures the wrist heart sound module as a MESH network. node, and initialize various Bluetooth services;

S32,创建定时器任务来定时采集第二心音模块,通过蓝牙服务将腕部心音信号发送至中心模块。S32 , a timer task is created to periodically collect the second heart sound module, and the wrist heart sound signal is sent to the central module through the Bluetooth service.

与现有技术相比,针对当前设备测量信号种类不全的问题,本发明通过直接测量可以获得心率、温度、人体心音、PPG等信号,而通过间接测量可以获得人体血压信号。本发明通过胸前和手腕心音信号和PPG信号提取特征值由相应的血压预测模型来计算血压值。使用特征值的方法预测血压信号的算法复杂度低可以在低功耗、低速率的设备上运行。同时使用手腕处和胸前的心音信号和PPG信号提取特征值来计算血压可以提高血压信号的准确性。Compared with the prior art, the present invention can obtain heart rate, temperature, human heart sounds, PPG and other signals through direct measurement, and can obtain human blood pressure signals through indirect measurement. The present invention calculates the blood pressure value from the corresponding blood pressure prediction model by extracting characteristic values from the chest and wrist heart sound signals and PPG signals. The algorithmic complexity of predicting blood pressure signals using eigenvalue methods is low and can be run on low-power, low-rate devices. Using the heart sound signal and PPG signal at the wrist and chest at the same time to extract the eigenvalues to calculate the blood pressure can improve the accuracy of the blood pressure signal.

附图说明Description of drawings

为了使本发明的目的、技术方案和有益效果更加清楚,本发明提供如下附图进行说明:In order to make the purpose, technical solutions and beneficial effects of the present invention clearer, the present invention provides the following drawings for description:

图1为本发明实施例人体生命体征监测装置的结构框图;1 is a structural block diagram of a human vital sign monitoring device according to an embodiment of the present invention;

图2为本发明实施例人体生命体征监测装置的中心模块结构框图;2 is a block diagram of a central module structure of a human vital sign monitoring device according to an embodiment of the present invention;

图3为本发明实施例人体生命体征监测装置的第一心音模块结构框图;3 is a structural block diagram of a first heart sound module of a human vital sign monitoring device according to an embodiment of the present invention;

图4为本发明实施例人体生命体征监测装置的腕部心音模块结构框图;4 is a structural block diagram of a wrist heart sound module of a human vital sign monitoring device according to an embodiment of the present invention;

图5为本发明实施例人体生命体征监测方法的步骤流程图;5 is a flowchart of steps of a method for monitoring human vital signs according to an embodiment of the present invention;

图6为本发明实施例人体生命体征监测方法的S3腕部心音采集流程图;6 is a flow chart of S3 wrist heart sound collection in a method for monitoring human vital signs according to an embodiment of the present invention;

图7为本发明实施例人体生命体征监测方法的血压预测步骤流程图。FIG. 7 is a flowchart of blood pressure prediction steps of a method for monitoring human vital signs according to an embodiment of the present invention.

具体实施方式Detailed ways

下面将结合附图,对本发明的优选实施例进行详细的描述。The preferred embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

装置实施例参见图1-4,包括中心模块1、第一心音模块5和腕部心音模块 10,第一心音模块5和腕部心音模块10均与中心模块1连接,其中,1-4, the device embodiment includes a central module 1, a first heart sound module 5 and a wrist heart sound module 10, and the first heart sound module 5 and the wrist heart sound module 10 are both connected with the central module 1, wherein,

中心模块1包括第一NRF52832蓝牙最小系统板2、PPG模块3、体温模块 4和存储模块6;PPG模块3、体温模块4和存储模块6均与第一NRF52832蓝牙最小系统板2连接,PPG模块3采集人体PPG信号,体温模块4采集人体体表温度信号,第一心音模块5采集人体胸前心音信号,腕部心音模块10采集腕部的心音信号,存储模块6将采集到的各生命体征信号进行存储,第一 NRF52832蓝牙最小系统板2读取PPG模块3、体温模块4和第一心音模块5 的信号及数据,控制向存储模块6中写入数据并且通过BLE4.2协议向上位机发送数据;The central module 1 includes a first NRF52832 Bluetooth minimum system board 2, a PPG module 3, a body temperature module 4 and a storage module 6; the PPG module 3, the body temperature module 4 and the storage module 6 are all connected to the first NRF52832 Bluetooth minimum system board 2, and the PPG module 3 collects the PPG signal of the human body, the body temperature module 4 collects the temperature signal of the human body surface, the first heart sound module 5 collects the heart sound signal of the human chest, the wrist heart sound module 10 collects the heart sound signal of the wrist, and the storage module 6 stores the collected life The physical sign signal is stored, the first NRF52832 Bluetooth minimum system board 2 reads the signals and data of the PPG module 3, the body temperature module 4 and the first heart sound module 5, and controls the writing of data to the storage module 6 and upward through the BLE4.2 protocol. Bit machine sends data;

利用光电容积描记(photo platysma graph,PPG)技术进行人体运动心率的检测是红外无损检测技术在生物医学中的一个应用.它利用光电传感器,检测经过人体血液和组织吸收后的反射光强度的不同,描记出血管容积在心动周期内的变化,从得到的脉搏波形中计算出心率。The detection of human heart rate using photoplethysmography (PPG) technology is an application of infrared non-destructive testing technology in biomedicine. It uses photoelectric sensors to detect the difference in reflected light intensity after absorption by human blood and tissue , trace the changes of vascular volume during the cardiac cycle, and calculate the heart rate from the obtained pulse waveform.

第一心音模块5包括依次连接的PVDF传感器9、模数信号转换器7和信号滤波及放大电路8,其中,PVDF传感器9采集人体的心音信息并转换为电压信号,信号滤波及放大电路8对PVDF传感器9产生的电信号进行滤波处理降低噪声对心音信号的干扰并对信号进行放大,模数信号转换器7接收信号滤波及放大电路8处理过后的电信号并转换为数字信号输出给中心模块1。The first heart sound module 5 includes a PVDF sensor 9, an analog-to-digital signal converter 7 and a signal filtering and amplifying circuit 8 connected in sequence, wherein the PVDF sensor 9 collects the heart sound information of the human body and converts it into a voltage signal, and the signal filtering and amplifying circuit 8 The electrical signal generated by the PVDF sensor 9 is filtered to reduce the interference of noise on the heart sound signal and the signal is amplified. The analog-to-digital signal converter 7 receives the electrical signal processed by the signal filtering and amplifying circuit 8 and converts it into a digital signal for output to the center. Module 1.

心音是心脏跳动过程中对胸壁的冲击振动,用聚偏氟乙烯(PVDF)压电传感器等仪器可记录心音的机械振动,称为心音图。在检测模拟人的心音时,PVDF 传感器9先将心音振动信号转换为微弱电信号,心音测量系统则将该微弱电信号经两级前置放大器、带通滤波器、50Hz陷波器、电压提升电路等处理后作为输出信号送至示波器,在示波器上显示心音波形并测量各项指标(包括心率、幅值、舒张期和收缩期时限等),然后与模拟人的心音标准值进行比较。Heart sounds are the shock and vibration of the chest wall during the beating of the heart, and the mechanical vibration of heart sounds can be recorded by instruments such as polyvinylidene fluoride (PVDF) piezoelectric sensors, which is called a phonocardiogram. When detecting the simulated human heart sound, the PVDF sensor 9 first converts the heart sound vibration signal into a weak electrical signal, and the heart sound measurement system passes the weak electrical signal through a two-stage preamplifier, a band-pass filter, a 50Hz notch filter, and a voltage boost. After the circuit is processed, it is sent to the oscilloscope as an output signal, and the heart sound waveform is displayed on the oscilloscope and various indicators (including heart rate, amplitude, diastolic and systolic time limit, etc.) are measured, and then compared with the standard value of the simulated human heart sound.

腕部心音模块10包括相连接的第二NRF52832蓝牙最小系统板11和第二心音模块12,第二心音模块12采集腕部的心音信号,第二NRF52832蓝牙最小系统板11接收第二心音模块12采集的数据并向中心模块1发送。The wrist heart sound module 10 includes a connected second NRF52832 Bluetooth minimum system board 11 and a second heart sound module 12 , the second heart sound module 12 collects the heart sound signal of the wrist, and the second NRF52832 Bluetooth minimum system board 11 receives the second heart sound module 12 The collected data is sent to the central module 1.

PPG模块3包括MAX30100脉搏血氧和心率检测传感器。使用了两个LED 灯,一个用来优化光学的光电探测器,和低噪声模拟信号处理器,另一个用来检测脉搏的血氧和心率信号。Max30100的运行电压在1.8V到3.3V之间,并且可以通过软件来控制,待机电流极小,可以忽略不计,这样可以使电源在如何时候都能保持连接状态。PPG module 3 includes a MAX30100 pulse oximetry and heart rate detection sensor. Two LED lights are used, one photodetector to optimize optics, and a low noise analog signal processor, and the other to detect pulse oxygen and heart rate signals. The operating voltage of the Max30100 is between 1.8V and 3.3V, and it can be controlled by software. The standby current is very small and can be ignored, so that the power supply can be kept connected at any time.

体温模块4包括CJMCU30205人体温传感器。The body temperature module 4 includes a CJMCU30205 human body temperature sensor.

存储模块6包括W25Q16存储器,是16M-bit(1bytes=8bits)的flash,可以保存voice,text,data。The storage module 6 includes a W25Q16 memory, which is a 16M-bit (1bytes=8bits) flash, which can store voice, text, and data.

方法实施例参见图5,包括以下步骤:Referring to Figure 5, the method embodiment includes the following steps:

S1,中心模块1布置在人体胸前,上电后第一NRF52832蓝牙最小系统板 2设置基本蓝牙广播模式让其它蓝牙设备可以发现并且建立连接,由上位机将中心模块1配置为MESH网络中的节点,并且初始化各种蓝牙服务;S1, the central module 1 is arranged on the chest of the human body. After power-on, the first NRF52832 Bluetooth minimum system board 2 sets the basic Bluetooth broadcast mode so that other Bluetooth devices can discover and establish connections. The host computer configures the central module 1 as a network in the MESH network node, and initialize various Bluetooth services;

S2,创建定时器任务来定时采集PPG模块3、体温模块4和第一心音模块5的数据,并存入存储模块6;S2, create a timer task to periodically collect the data of the PPG module 3, the body temperature module 4 and the first heart sound module 5, and store them in the storage module 6;

S3,接收腕部心音模块10传输的腕部心音后,通过血压预测模型得到实时的血压信号,将所有的生命体征打包通过蓝牙服务向主机发送数据包;S3, after receiving the wrist heart sound transmitted by the wrist heart sound module 10, obtain the real-time blood pressure signal through the blood pressure prediction model, and package all the vital signs to send data packets to the host through the Bluetooth service;

S4,接收上位机的返回数据验证是否数据传输正常,若发生丢包或数据错误则重新发送数据包。S4: Receive the returned data from the host computer to verify whether the data transmission is normal, and resend the data packet if packet loss or data error occurs.

S2具体包括以下步骤:S2 specifically includes the following steps:

S21,第一心音模块5在上电后由中心模块1进行初始化;S21, the first heart sound module 5 is initialized by the central module 1 after being powered on;

S22,PVDF传感器9采集人体的心音信号,采集到的信号通过信号滤波及放大电路8处理过后滤除工频噪声以及环境噪声,并将信号幅值放大到2.0V到 3.3V区间;S22, the PVDF sensor 9 collects the heart sound signal of the human body, and the collected signal is processed by the signal filtering and amplifying circuit 8 to filter out power frequency noise and environmental noise, and amplify the signal amplitude to the range of 2.0V to 3.3V;

S23,由模数信号转换器7将放大后的信号转换为数字信号等待中心模块1 的采集。S23 , the amplified signal is converted into a digital signal by the analog-to-digital signal converter 7 and waits for collection by the central module 1 .

参见图6,S3具体包括以下步骤:Referring to Figure 6, S3 specifically includes the following steps:

S31,腕部心音模块10布置在手腕处,在上电后第二NRF52832蓝牙最小系统板11设置基本蓝牙广播模式让其它蓝牙设备可以发现并且建立连接,由上位机将腕部心音模块10配置为MESH网络中的节点,并初始化各种蓝牙服务;S31, the wrist heart sound module 10 is arranged at the wrist, after power-on, the second NRF52832 Bluetooth minimum system board 11 sets the basic Bluetooth broadcast mode so that other Bluetooth devices can discover and establish connections, and the upper computer configures the wrist heart sound module 10 as Nodes in the MESH network and initialize various Bluetooth services;

S32,创建定时器任务来定时采集第二心音模块12,通过蓝牙服务将腕部心音信号发送至中心模块1。S32 , a timer task is created to periodically collect the second heart sound module 12 , and the wrist heart sound signal is sent to the central module 1 through a Bluetooth service.

参见图7,为本发明的血压预测步骤流程图,当中心模块1和腕部心音模块10采集得到了PPG信号和胸前、手腕处的心音信号后,再经过平滑滤波后,进行PPG信号和心音信号的起始点识别,根据起始点对信号进行周期划分,再以周期为基本单位计算PPG信号和心音信号的各项特征值,将特征值带入血压预测模型计算得到血压值,血压预测模型的参数为经验值。Referring to FIG. 7 , it is a flowchart of the blood pressure prediction steps of the present invention. After the central module 1 and the wrist heart sound module 10 collect the PPG signal and the heart sound signal at the chest and wrist, after smooth filtering, the PPG signal and the heart sound signal at the wrist are collected. The starting point of the heart sound signal is identified, the signal is divided into periods according to the starting point, and then the eigenvalues of the PPG signal and the heart sound signal are calculated with the period as the basic unit, and the eigenvalues are brought into the blood pressure prediction model to calculate the blood pressure value. The blood pressure prediction model The parameters are empirical values.

以上仅为本发明的较佳实施例而已,并不用以限制本发明,凡在本发明的精神和原则之内所作的任何修改、等同替换和改进等,均应包含在本发明的保护范围之内。The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements and improvements made within the spirit and principles of the present invention shall be included in the protection scope of the present invention. Inside.

Claims (8)

1. A human body vital sign monitoring device is characterized by comprising a central module, a first heart sound module and a wrist heart sound module, wherein the first heart sound module and the wrist heart sound module are both connected with the central module,
the central module comprises a first NRF52832 Bluetooth minimum system board, a PPG module, a body temperature module and a storage module; the PPG module, the body temperature module and the storage module are all connected with a first NRF52832 Bluetooth minimum system board, the PPG module collects PPG signals of a human body, the body temperature module collects body surface temperature signals of the human body, the first heart sound module collects precordial heart sound signals of the human body, the wrist heart sound module collects heart sound signals of the wrist, the storage module stores the collected vital sign signals, the first NRF52832 Bluetooth minimum system board reads signals and data of the PPG module, the body temperature module and the first heart sound module, and controls to write data into the storage module and send the data to an upper computer through a BLE4.2 protocol;
the first heart sound module comprises a PVDF sensor, an analog-digital signal converter and a signal filtering and amplifying circuit which are sequentially connected, wherein the PVDF sensor collects heart sound information of a human body and converts the heart sound information into a voltage signal, the signal filtering and amplifying circuit carries out filtering processing on an electric signal generated by the PVDF sensor to reduce noise interference on a heart sound signal and amplifies the signal, and the analog-digital signal converter receives the electric signal processed by the signal filtering and amplifying circuit and converts the electric signal into a digital signal to be output to the center module.
2. The human vital signs monitoring device of claim 1, wherein the wrist heart sound module comprises a second NRF52832 bluetooth minimal system board and a second heart sound module connected to each other, the second heart sound module collects heart sound signals of the wrist, and the second NRF52832 bluetooth minimal system board receives data collected by the second heart sound module and transmits the data to the central module.
3. Human vital signs monitoring device according to claim 1, wherein the PPG module comprises a MAX30100 pulse oximetry and heart rate detection sensor.
4. The human vital signs monitoring device of claim 1, wherein the body temperature module comprises a CJMCU30205 human body temperature sensor.
5. Human vital signs monitoring device according to claim 1, wherein the memory module comprises a W25Q16 memory.
6. Method for monitoring human vital signs, characterized in that the device according to any one of claims 1 to 5 is used, comprising the following steps:
s1, arranging a center module in front of the chest of a human body, setting a basic Bluetooth broadcast mode by a first NRF52832 Bluetooth minimum system board after electrification to enable other Bluetooth devices to discover and establish connection, configuring the center module as a node in an MESH network by an upper computer, and initializing various Bluetooth services;
s2, a timer task is established to acquire data of the PPG module, the body temperature module and the first heart sound module at regular time and store the data in a storage module;
s3, after receiving the wrist heart sounds transmitted by the wrist heart sound module, obtaining real-time blood pressure signals through a blood pressure prediction model, packaging all vital signs and sending data packets to a host through Bluetooth service;
and S4, receiving the returned data of the upper computer to verify whether the data transmission is normal, and resending the data packet if packet loss or data error occurs.
7. The method according to claim 6, wherein the S2 specifically comprises the following steps:
s21, the first heart sound module is initialized by the central module after being electrified;
s22, acquiring heart sound signals of a human body by the PVDF sensor, filtering power frequency noise and environmental noise after the acquired signals are processed by a signal filtering and amplifying circuit, and amplifying the signal amplitude to a range from 2.0V to 3.3V;
and S23, converting the amplified signal into a digital signal by the analog-to-digital signal converter to wait for the acquisition of the central module.
8. The method according to claim 6, wherein the S3 specifically comprises the following steps:
s31, the wrist heart sound module is arranged on the wrist, after the wrist heart sound module is powered on, the second NRF52832 Bluetooth minimum system board sets a basic Bluetooth broadcast mode to enable other Bluetooth devices to discover and establish connection, the wrist heart sound module is configured into nodes in an MESH network by the upper computer, and various Bluetooth services are initialized;
and S32, creating a timer task to acquire a second heart sound module at regular time, and sending the wrist heart sound signal to the center module through the Bluetooth service.
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