CN114367029A - Magnetic drive separation built-in type fluctuation pumping blood ventricle blood pump - Google Patents

Abstract

The invention discloses a magnetic drive partitioned built-in wave pumping blood ventricular blood pump, comprising a pump body assembly formed by snapping a pump cover on a pump body, the pump cover is provided with a blood outlet, and the pump body is provided with an inner baffle, The inner baffle divides the inner cavity of the pump body assembly into a flow cavity and a driving cavity, and the pump body is provided with a blood inlet. The guide assembly passes through the opening on the inner partition plate and passes through the flow cavity and the drive cavity. The guide assembly is sleeved with a driven assembly. The part of the driven assembly in the drive cavity is embedded with a permanent magnet, and the part in the flow cavity is connected with the intermediate part. The guide assembly is connected with the flexible membrane assembly between the pump cover, and the magnetic drive assembly installed in the drive cavity is arranged around the permanent magnet. Under the action of the alternating magnetic field of the magnetic drive component, the driven component drives the flexible membrane component to oscillate, causing the flexible membrane to fluctuate in the radial direction to achieve fluctuating pumping of blood, thereby reducing the risk of complications such as hemolysis and thrombosis, and improving blood compatibility.

Description

Magnetic drive separator built-in wave pumping blood ventricular blood pump

technical field

The invention relates to a magnetic drive separation built-in wave pumping blood ventricular blood pump, which belongs to the technical field of ventricular blood pumps.

Background technique

Ventricular assist device is currently a common medical device for the clinical treatment of end-stage heart failure, mainly left ventricular assist device. The core component of the left ventricular assist device is the left ventricular blood pump. At present, there are two main types of left ventricular blood pumps: axial flow and magnetic levitation centrifugal. These two types of left ventricular blood pumps use the principle of mechanical rotation, that is, relying on the high-speed rotation of the rotor to do work on the blood, and convert the mechanical energy of rotation into pressure potential energy on the blood, thereby producing a pumping effect on the blood and supplying the blood. to all organs of the body. However, from the actual use, it can be found that after long-term use of these two left ventricular blood pumps, on the one hand, many complications will occur, such as the loss of pulsatile blood flow in the patient's body, thereby causing organ inflammation, gastrointestinal bleeding, main Complications such as arterial regurgitation can even lead to death of patients in severe cases. On the other hand, hemolysis, thrombosis and other blood compatibility problems need to be solved.

SUMMARY OF THE INVENTION

The purpose of the present invention is to provide a magnetic drive separation built-in wave pumping blood ventricular blood pump, which achieves the effect of wave pumping on blood, and has the advantages of reducing the risk of complications such as hemolysis and thrombosis, improving blood compatibility, etc. Features.

In order to achieve the above object, the present invention adopts the following technical solutions:

A magnetic drive separation built-in wave pumping blood ventricular blood pump is characterized in that: it includes a pump body assembly formed by a disc-shaped pump cover buckled on a barrel-shaped pump body, the pump cover is provided with a blood outlet, and the pump body is provided with a blood outlet. There is an inner baffle, which divides the inner cavity of the pump body assembly into a flow cavity and a drive cavity, the flow cavity is between the pump cover and the inner baffle, and the flow cavity communicates with the drive cavity through the opening on the inner baffle , the pump body is provided with a blood inlet on the part opposite to the flow cavity; the guide assembly is arranged through the opening in the flow cavity and the drive cavity, the guide assembly is movably sleeved with a driven assembly, and the driven assembly is located on the part of the drive cavity A permanent magnet is embedded, the part of the driven component in the flow chamber is fixedly connected with the flexible membrane component, the flexible membrane component is between the guide component and the pump cover, and the magnetic drive component installed in the drive cavity is arranged around the permanent magnet; Under the action of the alternating magnetic field generated by the component, the driven component fixed with the permanent magnet makes an oscillating motion on the guiding component, and the driven component drives the flexible membrane component to make an oscillating motion, so that the flexible membrane of the flexible membrane component moves along its own radial direction. The direction fluctuates, which in turn causes the blood flowing into the blood inlet to flow out of the blood outlet under the undulating action of the flexible membrane.

The advantages of the present invention are:

The invention converts the deformation energy of the flexible membrane into the pressure potential energy of the blood, and realizes the effect of wave pumping for the blood. On the one hand, the flexible membrane with small stiffness moves softly, and compared with the existing left ventricular blood pump, the shear stress on the blood is much smaller, and the flexible membrane does not rotate, so it can effectively avoid the process of pumping blood. The generation of non-physiological flow characteristics such as high rotational speed and high shear force reduces the risk of complications such as hemolysis and thrombosis. In addition, the structural design of the present invention improves blood compatibility.

Description of drawings

FIG. 1 is a schematic structural diagram of a ventricular blood pump of the present invention.

FIG. 2 is a schematic perspective view of the flexible membrane assembly.

FIG. 3 is a schematic perspective view of a metal ring.

Figure 4 is a schematic perspective cross-sectional view of the pump body assembly with the guide assembly installed.

Figure 5 is a schematic perspective view of the pump cover.

FIG. 6 is a schematic perspective cross-sectional view of the pump body.

FIG. 7 is a schematic perspective view of a driven assembly.

FIG. 8 is an enlarged schematic view of the sawtooth structure of the ring frame of the driven assembly facing the enclosure and the guide plate.

FIG. 9 is a schematic view of the flexible film of the present invention in a wave state.

Detailed ways

As shown in FIGS. 1 to 9 , the magnetic drive partitioned built-in wave pumping blood ventricular blood pump of the present invention includes a pump body assembly 30 formed by snapping a disc-shaped pump cover 31 on the opening of a barrel-shaped pump body 32 . The cover 31 is provided with a blood outlet 310, and the pump body 32 is provided with an inner partition 321. The inner partition 321 divides the inner cavity of the pump body assembly 30 into a flow cavity 33 and a drive cavity 34. The flow cavity 33 is between the pump cover 31. Between the inner baffle 321, the flow cavity 33 communicates with the driving cavity 34 through the opening 3210 opened on the inner baffle 321, and a blood inlet 320 is provided on the part (side wall) opposite to the flow cavity 33 on the pump body 32. The inlet 320 is communicated with the blood outlet 310 via the flow chamber 33; the guide assembly 50 is arranged through the opening 3210 in the flow chamber 33 and the drive chamber 34, the guide assembly 50 is movably sleeved with the driven assembly 40, and the driven assembly 40 is located in the drive chamber The permanent magnet 60 is embedded on the part of 34, the part of the driven assembly 40 in the flow chamber 33 is fixedly connected with the flexible membrane assembly 10, the flexible membrane assembly 10 is between the guide assembly 50 and the pump cover 31, and the drive chamber 34 is installed in the The magnetic drive assembly 20 is arranged around the permanent magnet 60; under the action of the alternating magnetic field generated by the magnetic drive assembly 20, the driven assembly 40 fixed with the permanent magnet 60 oscillates on the guide assembly 50 while the driven assembly 40 drives the The flexible membrane assembly 10 oscillates in the narrow flow channel 70 formed between the pump cover 31 and the guide assembly 50, so that the flexible membrane 11 of the flexible membrane assembly 10 fluctuates along the radial direction of the flexible membrane 11 itself, that is, the flexible membrane 11 produces an effect similar to the flapping of fish tail fins, so that after the blood flowing into the blood inlet 320 flows into the flow channel 70, it flows out from the blood outlet 310 under the undulating action of the flexible membrane 11, so as to achieve the effect of undulating pumping blood.

As shown in FIG. 1 and FIG. 2 , the flexible membrane assembly 10 includes a circular flexible membrane 11 with elasticity. A guide opening 110 is provided in the center of the flexible membrane 11 , and the diameter of the guide opening 110 should be close to the inner diameter of the blood outlet 310 to promote blood flow A metal ring 12 is embedded in the peripheral edge of the flexible film 11. When the metal connecting seat 121 fixed on the metal ring 12 protrudes out of the flexible film 11, the side wall of the metal connecting seat 121 is extended by the flexible film 11 (see Fig. 2. The part indicated by the reference numeral 113) is wrapped, in other words, the metal connecting seat 121 only exposes its end surface for connecting with the metal connecting piece 43 of the driven component 40.

Usually, the metal connection seats 121 are evenly distributed along the circumference of the metal ring 12 , and the number of the metal connection seats 121 can be reasonably designed according to the actual situation.

In the present invention, the function of the diversion port 110 is to better distribute the blood on the upper and lower surfaces of the flexible membrane 11 when the blood flows through the flexible membrane 11 .

In the present invention, the function of the metal ring 12 is to enhance the effect of the reciprocating motion of the peripheral edge portion of the flexible membrane 11 itself, which is beneficial to increase the pressure on the blood.

As shown in FIG. 2 , the peripheral edge portion of the metal ring 12 embedded in the flexible film 11 (ie, the inclined area 112 shown in FIG. 2 ) is thick on the outside and thin on the inside, while the remaining part, that is, the part outside the metal ring 12 embedded in the flexible film 11 (ie, the part shown in FIG. 2 ) 2) the thickness of the horizontal area 111) is uniform, wherein: when the flexible membrane 11 is in the narrow flow channel 70 formed between the pump cover 31 and the guide assembly 50, between the flexible membrane 11 and the pump cover 31, between the flexible membrane 11 and the A gap is left between the guide assemblies 50 .

In practical design, for example, the flexible film 11 can be designed such that the thickness of the horizontal region 111 is 0.5mm-1mm, the thickness of the inclined region 112 increases from the inside to the outside, and the final thickness of the peripheral edge is 1mm-1.5mm. In addition, the gap between the flexible membrane 11 and the pump cover 31 and the guide plate 51 is designed to be about 1 mm.

In the actual design, the metal ring 12 with the metal connecting seat 121 is integrally injection-molded with the flexible film 11 .

In the present invention, the flexible film 11 is made of organic silicon or polyurethane composite material, which has the characteristics of low rigidity and low density. The elastic characteristics of the flexible film 11 can store the deformation energy and release it when large deformation occurs. is the pressure potential energy on the blood. In practice, the manufacturing material of the flexible membrane 11 is not limited, as long as it can generate a large deformation wave effect along its radial direction under the combined action of the oscillating force and the fluid force.

In the present invention, the metal ring 12 and the metal connecting seat 121 on it are made of titanium alloy material. Since the rigidity and hardness of the metal ring 12 are greater than those of the flexible film 11, the center of the flexible film 11 can produce similar effects on blood. The effect of the work done by the piston strengthens the fluidity of the blood near the flexible membrane 11 , which achieves the effect of smooth blood transmission, and the effect of effectively flushing the flow channel and reducing the generation of thrombus.

As shown in FIG. 1 and FIG. 4 , the guide assembly 50 includes a guide plate 51 in the flow chamber 33 , one end of the guide column 52 is connected to the guide plate 51 , and the other end passes through the opening 3210 and is connected to the mounting seat provided in the drive chamber 34 323 is fixedly connected, and the connection between the guide post 52 and the mounting seat 323 can be connected by means of screwing, welding or bonding, which is not limited.

As shown in FIG. 1 and FIG. 7 , the driven assembly 40 includes a driven column 44. One end of the driven column 44 is connected to an annular frame 41 through a connecting beam 42 for improving structural strength. The annular frame 41 is provided with A plurality of metal connectors 43, the number and arrangement of the metal connectors 43 should be reasonably designed according to the number and arrangement of the metal connectors 121 of the flexible membrane module 10, and the other end of the driven column 44 is provided with a plurality of partition plates at intervals 45, an annular groove 46 is formed between two adjacent partition plates 45 (Fig. 7 shows a situation where two grooves 46 are provided), a permanent magnet 60 is fixed in the groove 46, and the adjacent permanent magnets 60 The polarities of the magnetic poles between them are opposite, for example, the polarity of the magnetic poles of the permanent magnets 60 adjacent to the permanent magnets 60 having the N magnetic pole polarity is S.

Further, under the action of the alternating magnetic field generated by the magnetic drive assembly 20, when the driven column 44 with the permanent magnet 60 fixed thereon is sleeved outside the guide column 52 through the through hole 440 provided in the axial direction on the driven column 44 and is guided in the guide column 52. When the oscillating movement is performed on the column 52, the ring frame 41 is sleeved outside the guide plate 51 and performs oscillating movement on the guide plate 51, and at the same time, the ring frame 41 drives the flexible film 11 to do the oscillating movement together, wherein: the flexible film 11 is connected by metal The fixed connection between the seat 121 and the metal connector 43 is fixed to the ring frame 41 .

As shown in FIG. 1 , the end face of the inner baffle 321 facing the flow chamber 33 is provided with an enclosure 322 , the annular frame 41 is interposed between the guide plate 51 and the enclosure 322 , and the annular frame 41 is connected to the guide plate 51 and the enclosure 322 contact. In the present invention, on the one hand, the enclosure 322 effectively prevents the blood flowing from the blood inlet 320 from bypassing the flexible membrane 11 and entering the driving cavity 34 to cause blood loss. At the same time, blood is effectively prevented from flowing into the driving cavity 34 from the gap therebetween, the loss of blood is reduced, and the blood pumping efficiency is improved.

As shown in FIG. 8 , a better design is that the ring frame 41 faces the guide plate 51 and the side wall of the enclosure 322 is provided with a sawtooth structure 410 to improve sealing performance and prevent blood penetration, that is, the ring frame 41 is located between the enclosure 322 and the enclosure 322. During the oscillating movement between the guide discs 51 , the sawtooth structure 410 more effectively prevents blood from flowing into the drive cavity 34 from the gap between the annular frame 41 , the enclosure 322 and the guide disc 51 . In actual design, the sawtooth structure 410 includes multiple rows of sawtooths, and the shape of the sawtooth may be triangular, rectangular, etc., which is not limited.

As shown in FIG. 1 , the end surface of the guide plate 51 facing the flexible membrane 11 is provided with a conical-shaped guide cone 510 . The guide cone 510 is arranged opposite to the blood outlet 310 , and a convex portion 311 is provided on the inner end surface of the pump cover 31 . The convex portion 311 The end surface facing the flexible film 11 is an arc-shaped convex surface 3110, wherein: the cross-sectional area of the convex portion 311 is equal to or approximately equal to the cross-sectional area of the guide plate 51, and a flow between the convex portion 311 and the guide plate 51 is thin in the middle and thick in the surrounding area. The channel 70, that is, the flow channel 70 has the smallest space in the center, and the space gradually expands outward along its radial direction, which is beneficial for the flexible membrane 11 to get closer to the convex portion 311 when it performs oscillating motion and generates wave motion in its radial direction. , and guide the surface of the disc 51, so as to form a "blood bag" that is conducive to the outward transport of blood and reduce the phenomenon of backflow.

In actual design, in order to facilitate the connection between the metal connector 43 and the metal connector seat, the edge of the guide plate 51 can be designed to be stepped, as shown in FIG. 1 .

As shown in FIG. 1 , the magnetic drive assembly 20 includes a coil bobbin 21 arranged in the drive cavity 34 along the inner wall of the pump body 32 . The bobbin 21 is provided with a plurality of annular wire slots 210 ( FIG. The case of the wire slot 210), the electromagnetic coil 22 is wound in the wire slot 210, and the electromagnetic coil 22 is arranged around the permanent magnet 60, that is, the part of the driven component 40 where the permanent magnet 60 is fixed and the guide post 52 pass through the central hole of the coil frame 21 ( (not marked in the figure) setting, wherein: there is a certain gap between the permanent magnet 60 and the electromagnetic coil 22, and the size of the gap should be reasonably designed according to the actual situation.

In the actual design, the electromagnetic coil 22 adopts copper wire, and the cable connected to the electromagnetic coil 22 is led out to the outside through the coil frame 21 and the pump body 32 to be connected with the relevant power supply equipment.

In the actual design, the pump cover 31 , the pump body 32 , the inner partition 321 and the enclosure 322 are made of titanium alloy material with excellent blood compatibility. The pump cover 31 and the pump body 32 can be connected to each other by bolts. The fastening is fastened. Except for the blood inlet 320, both of them are of axisymmetric structure, and the coaxiality should be ensured when the two are fastened and installed.

In addition, in the present invention, the guide assembly 50 and the driven assembly 40 are also made of titanium alloy material. In other words, the parts that need to be in contact with blood in the present invention should be made of titanium alloy to improve blood compatibility.

The magnetic drive separation built-in wave pumping blood ventricular blood pump of the present invention is mainly used as a left ventricular blood pump. When in use, the electromagnetic coil 22 is fed with a changing current to form an alternating magnetic field, and the alternating magnetic field has an attraction and repulsion effect on the permanent magnets 60 with different magnetic pole polarities of N and S, so the permanent magnet 60 drives the slave under the action of the alternating magnetic field. The component 40 oscillates on the guide component 50 , and then the driven component 40 drives the flexible membrane 11 to do the same frequency and the same amplitude in the narrow flow channel 70 through the connection structure between the metal connecting piece 43 and the metal connecting seat 121 . Oscillating motion (oscillation amplitude is around 1mm). Therefore, the flexible membrane 11 oscillates and fluctuates in its radial direction at the same time, similar to the effect of flapping the fins of the fish tail, so that the flexible membrane 11 converts the deformation energy generated by the flexible membrane 11 into pressure potential energy on the blood, so that the inflowing The blood in the blood inlet 320 is directly pumped to the blood outlet 310 by the fluctuation under the undulating action of the flexible membrane 11 and under the guiding action of the guide cone 510 and the diversion port 110 .

In the process of pumping blood, the structure design between the ring frame 41, the guide plate 51 and the enclosure 322, especially the design of the sawtooth structure 410, can effectively block the blood from the ring frame 41 and the guide plate 51, The gap between the enclosures 322 flows into the driving cavity 34, thereby reducing the loss of blood and improving the blood pumping effect.

The above are the preferred embodiments of the present invention and the technical principles used by them. For those skilled in the art, without departing from the spirit and scope of the present invention, any technology based on the technical solutions of the present invention, etc. Obvious changes such as effective transformation, simple replacement, etc., all fall within the protection scope of the present invention.

Claims (9)

1. a magnetic drive separate built-in wave pumping blood ventricular blood pump, it is characterized in that: it comprises the pump body assembly that the disc-shaped pump cover is buckled and formed on the barrel-shaped pump body, and the pump cover is provided with a blood outlet, There is an inner baffle in the pump body. The inner baffle divides the inner cavity of the pump body assembly into a flow cavity and a drive cavity. The flow cavity is between the pump cover and the inner baffle, and the flow cavity is connected to the drive through the opening on the inner baffle. The cavity is connected, and a blood inlet is provided on the pump body opposite to the flow cavity; the guide assembly is arranged through the opening in the flow cavity and the drive cavity, and the guide assembly is movably sleeved with a driven assembly, and the driven assembly is located in the driving cavity. A permanent magnet is embedded on the part, the part of the driven component in the flow cavity is fixedly connected with the flexible membrane component, the flexible membrane component is between the guide component and the pump cover, and the magnetic drive component installed in the driving cavity is arranged around the permanent magnet; Under the action of the alternating magnetic field generated by the magnetic drive assembly, while the driven assembly fixed with the permanent magnets oscillates on the guide assembly, the driven assembly drives the flexible membrane assembly to make an oscillating motion, so that the flexible membrane of the flexible membrane assembly moves along itself. Fluctuations are generated in the radial direction, and then the blood flowing into the blood inlet flows out of the blood outlet due to the fluctuation of the flexible membrane. 2. The magnetic drive separation built-in wave pumping blood ventricular blood pump as claimed in claim 1 is characterized in that: The flexible membrane assembly includes a circular flexible membrane, the center of the flexible membrane is provided with a diversion port, and a metal ring is embedded in the periphery of the flexible membrane. The side walls are wrapped by an extended flexible membrane. 3. The magnetic drive separation built-in wave pumping blood ventricular blood pump as claimed in claim 2 is characterized in that: The periphery of the flexible membrane embedded with the metal ring is partially thick on the outside and thin on the inside, and the thickness of the remaining part is uniform, wherein: when the flexible membrane is in the flow channel formed between the pump cover and the guide assembly, There are gaps between the flexible membrane and the pump cover and between the flexible membrane and the guide assembly. 4. The magnetic drive separation built-in wave pumping blood ventricular blood pump as claimed in claim 2 is characterized in that: The metal ring with the metal connection seat is integrally injection-molded with the flexible film. 5. The magnetic drive separation built-in wave pumping blood ventricular blood pump as claimed in claim 2 is characterized in that: The guide assembly includes a guide plate in the flow cavity, one end of the guide column is connected with the guide plate, and the other end is fixedly connected with the assembly seat provided in the drive cavity after passing through the opening; The driven assembly includes a driven column, one end of the driven column is connected with a ring frame through a connecting beam, the ring frame is provided with a plurality of metal connectors, and the other end of the driven column is provided with a plurality of partitions a plate, an annular groove is formed between two adjacent partition plates, the permanent magnet is fixed in the groove, and the magnetic poles between the adjacent permanent magnets are opposite in polarity; Under the action of the alternating magnetic field generated by the magnetic drive assembly, when the driven column fixed with the permanent magnet is sleeved outside the guide column through the perforations on the driven column and oscillates on the guide column, the ring frame Sleeve outside the guide plate and make an oscillating motion on the guide plate, and at the same time, the ring frame drives the flexible film to make an oscillating motion together, wherein: the flexible film is connected by the fixed connection between the metal connecting seat and the metal connecting piece. Fixed with ring frame. 6. The magnetic drive separation built-in wave pumping blood ventricular blood pump as claimed in claim 5, characterized in that: An enclosure is provided on the end face of the inner baffle facing the flow cavity, the annular frame is interposed between the guide plate and the enclosure, and the annular frame is in phase with the guide plate and the enclosure. touch. 7. The magnetic drive separation built-in wave pumping blood ventricular blood pump as claimed in claim 6, characterized in that: The annular frame faces the guide plate, and the side wall of the enclosure is provided with a sawtooth structure to improve sealing performance and prevent blood penetration. 8. The magnetic drive separation built-in wave pumping blood ventricular blood pump as claimed in claim 5, characterized in that: The end face of the guide plate facing the flexible membrane is provided with a guide cone, the guide cone is arranged opposite to the blood outlet, the inner end face of the pump cover is provided with a convex portion, and the end face of the convex portion facing the flexible membrane is: Arc-shaped convex surface, wherein: the cross-sectional area of the convex portion is equal to that of the guide plate, and a flow channel with a thin middle and a thick surrounding is formed between the convex portion and the guide plate. 9. The magnetic drive partitioned built-in wave pumping blood ventricular blood pump according to any one of claims 2 to 8, characterized in that: The magnetic drive assembly includes a coil frame arranged in the drive cavity along the inner wall of the pump body, the coil frame is provided with a plurality of annular wire slots, and electromagnetic coils are wound in the wire slots, and the electromagnetic coils surround the Permanent magnet setup.

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