CN114344274A - Mitoq antioxidant hard capsule formula and preparation process - Google Patents
Mitoq antioxidant hard capsule formula and preparation process Download PDFInfo
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- CN114344274A CN114344274A CN202210008655.8A CN202210008655A CN114344274A CN 114344274 A CN114344274 A CN 114344274A CN 202210008655 A CN202210008655 A CN 202210008655A CN 114344274 A CN114344274 A CN 114344274A
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Abstract
The invention discloses a Mitoq antioxidant hard capsule formula and a preparation process thereof, wherein the Mitoq antioxidant hard capsule formula comprises the following raw materials in parts by weight: 10-30 mg of Mitoq molecules; 100-200 mg of vitamin E in parts by mass; astaxanthin accounts for 40-60 mg by mass; 40-60 mg of microcrystalline cellulose. The invention can slow down the oxidative stress damage of mitochondria and activate cell energy, thereby supporting the organ function and improving the long-term health level; strong oxidation resistance, can effectively remove free radicals and improve the anti-aging capability of human bodies.
Description
Technical Field
The invention relates to the technical field of antioxidant hard capsules, in particular to a formula and a preparation process of a Mitoq antioxidant hard capsule.
Background
Mitoq is the first high-order version of coenzyme Q10 antioxidant in the world that targets mitochondria, can penetrate the mitochondrial membrane and reach the inside of mitochondria, hundreds of times more potent than the common coenzyme Q10-resistant supplement. Mitochondria use Mitoq molecules to rearrange the distribution of mitochondrial membranes, helping to maintain their structural integrity and strengthen the defense barrier. This means that free radicals start to be neutralized and are effectively controlled, which brings a dual benefit to our body:
i, the normal energy production process of mitochondria is not influenced by free radicals;
and II, the risk of the cells in the body being invaded by free radicals is greatly reduced.
At present, the existing antioxidant hard capsules in China have some defects, such as; the antioxidant ingredients in the traditional antioxidant hard capsules in China hardly pass through a cell mitochondrial membrane, so that the oxidative stress damage of mitochondria is slowed down, the cell energy is activated, the functions of organs cannot be supported, and the long-term health level cannot be improved.
Disclosure of Invention
The invention aims to provide a formula and a preparation process of a Mitoq antioxidant hard capsule, and solves the problems in the background art.
In order to achieve the purpose, the invention provides the following technical scheme: a formulation of Mitoq antioxidant hard capsules and a preparation process thereof comprise the following raw materials in parts by weight: 10-30 mg of Mitoq molecules; 100-200 mg of vitamin E in parts by mass; astaxanthin accounts for 40-60 mg by mass; 40-60 mg of microcrystalline cellulose.
As a preferred embodiment of the invention, the formulation of the Mitoq antioxidant hard capsule comprises the following raw materials in parts by weight: the mass part of the Mitoq molecule is 10 mg; vitamin E100mg in parts by mass; astaxanthin accounts for 40mg in parts by mass; the microcrystalline cellulose content was 40mg parts by mass.
As a preferred embodiment of the invention, the formulation of the Mitoq antioxidant hard capsule comprises the following raw materials in parts by weight: the mass part of the Mitoq molecule is 20 mg; vitamin E150mg in parts by mass; 50mg of astaxanthin in parts by mass; the microcrystalline cellulose content was 50mg by mass.
As a preferred embodiment of the invention, the preparation process of the Mitoq antioxidant hard capsule formula comprises the following preparation steps:
a. weighing the raw materials in parts by weight;
b. after the step a is finished, putting Mitoq, vitamin E, astaxanthin and microcrystalline cellulose into a mixer, and uniformly mixing to obtain the content of the prepared capsule;
c. after the step b is finished, putting the raw materials of the empty capsules into a mixing machine for mixing, then carrying out sol, glue dipping, drying, shell pulling, cutting and finishing on the mixed raw materials to prepare the empty capsules, filling capsule contents into half of the empty capsules, and then sleeving half of the empty capsules with the filled empty capsules;
d. after the step c is finished, pressing the sleeved capsule by using a pressing machine, and cleaning medicinal powder attached to the outer part of the capsule shell to obtain a hard capsule;
e. and d, finishing, weight detecting and packaging the prepared hard capsule after the step d is finished.
In a preferred embodiment of the present invention, the rotation speed of the mixer in step b is 750-900 r/min, and the mixing time is 20-40 min.
As a preferred embodiment of the present invention, the capsule shell in step c is mainly prepared from the following raw materials: gelatin, plasticizer, glycerin, sodium carboxymethyl cellulose, thickener, opacifier and colorant.
As a preferred embodiment of the present invention, the weight of the prepared hard capsule in the step e is measured, and the weight of the hard capsule is 0.5 g/capsule.
Compared with the prior art, the invention has the following beneficial effects:
1. the capsule prepared by the invention can slow down the oxidative stress injury of mitochondria and activate cell energy, thereby supporting the functions of organs and improving the long-term health level.
2. The capsule prepared by the invention has strong oxidation resistance, can effectively remove free radicals in mitochondria and improve the anti-aging capability of human body.
Drawings
Other features, objects and advantages of the invention will become more apparent upon reading of the detailed description of non-limiting embodiments with reference to the following drawings:
fig. 1 is a flow chart of a Mitoq antioxidant hard capsule formulation and a preparation process thereof.
Detailed Description
Technical solutions in the embodiments of the present invention are clearly and completely described, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments.
Referring to fig. 1, the present invention provides a technical solution: a formulation of Mitoq antioxidant hard capsules and a preparation process thereof comprise the following raw materials in parts by weight: 10-30 mg of Mitoq molecules; 100-200 mg of vitamin E in parts by mass; astaxanthin accounts for 40-60 mg by mass; 40-60 mg of microcrystalline cellulose.
Further, the formula of the Mitoq antioxidant hard capsule comprises the following raw materials in parts by weight: the mass part of the Mitoq molecule is 10 mg; vitamin E100mg in parts by mass; astaxanthin accounts for 40mg in parts by mass; the microcrystalline cellulose content was 40mg parts by mass.
Further, the formula of the Mitoq antioxidant hard capsule comprises the following raw materials in parts by weight: the mass part of the Mitoq molecule is 20 mg; vitamin E150mg in parts by mass; 50mg of astaxanthin in parts by mass; the microcrystalline cellulose content was 50mg by mass.
Further, the preparation process of the Mitoq antioxidant hard capsule formula comprises the following preparation steps:
a. weighing the raw materials in parts by weight;
b. after the step a is finished, putting Mitoq, vitamin E, astaxanthin and microcrystalline cellulose into a mixer, and uniformly mixing to obtain the content of the prepared capsule;
c. after the step b is finished, putting the raw materials of the empty capsules into a mixing machine for mixing, then carrying out sol, glue dipping, drying, shell pulling, cutting and finishing on the mixed raw materials to prepare the empty capsules, filling capsule contents into half of the empty capsules, and then sleeving half of the empty capsules with the filled empty capsules;
d. after the step c is finished, pressing the sleeved capsule by using a pressing machine, and cleaning medicinal powder attached to the outer part of the capsule shell to obtain a hard capsule;
e. and d, finishing, weight detecting and packaging the prepared hard capsule after the step d is finished.
Further, the rotation speed of the mixer in the step b is 750-900 r/min during mixing, and the mixing time is 20-40 min.
Further, the capsule shell in the step c is mainly prepared from the following raw materials: gelatin, plasticizer, glycerin, sodium carboxymethyl cellulose, thickener, opacifier and colorant.
Further, in the step e, the weight of the prepared hard capsule is detected, and the weight of the hard capsule is 0.5 g/capsule.
Example one
The formula of the Mitoq antioxidant hard capsule comprises the following raw materials in parts by weight: the mass part of Mitoq is 10 mg; vitamin E100mg in parts by mass; astaxanthin accounts for 40mg in parts by mass; the microcrystalline cellulose content was 40mg parts by mass.
The preparation steps are as follows:
a. weighing the raw materials in parts by weight;
b. after the step a is finished, putting Mitoq, vitamin E, astaxanthin and microcrystalline cellulose into a mixer, and uniformly mixing to obtain the content of the prepared capsule;
c. after the step b is finished, putting the raw materials of the empty capsules into a mixing machine for mixing, then carrying out sol, glue dipping, drying, shell pulling, cutting and finishing on the mixed raw materials to prepare the empty capsules, filling capsule contents into half of the empty capsules, and then sleeving half of the empty capsules with the filled empty capsules;
d. after the step c is finished, pressing the sleeved capsule by using a pressing machine, and cleaning medicinal powder attached to the outer part of the capsule shell to obtain a hard capsule;
e. and d, finishing, weight detecting and packaging the prepared hard capsule after the step d is finished.
Example two
The formula of the Mitoq antioxidant hard capsule comprises the following raw materials in parts by weight: the mass part of Mitoq is 20 mg; vitamin E150mg in parts by mass; 50mg of astaxanthin in parts by mass; the microcrystalline cellulose content was 50mg by mass.
The preparation steps are as follows:
a. weighing the raw materials in parts by weight;
b. after the step a is finished, putting Mitoq, vitamin E, astaxanthin and microcrystalline cellulose into a mixer, and uniformly mixing to obtain the content of the prepared capsule;
c. after the step b is finished, putting the raw materials of the empty capsules into a mixing machine for mixing, then carrying out sol, glue dipping, drying, shell pulling, cutting and finishing on the mixed raw materials to prepare the empty capsules, filling capsule contents into half of the empty capsules, and then sleeving half of the empty capsules with the filled empty capsules;
d. after the step c is finished, pressing the sleeved capsule by using a pressing machine, and cleaning medicinal powder attached to the outer part of the capsule shell to obtain a hard capsule;
e. and d, finishing, weight detecting and packaging the prepared hard capsule after the step d is finished.
Data parameters of conventional antioxidant hard capsules table 1 are as follows:
example one antioxidant hard capsule data parameters table 2 is as follows:
examples parameters of the antioxidant hard capsules table 3 is as follows:
in summary, the data in tables 1, 2 and 3 are compared to obtain the capsule, which can slow down the oxidative stress damage of mitochondria and activate the cell energy, thereby supporting the organ function, improving the long-term health level, having strong oxidation resistance, effectively removing free radicals and improving the anti-aging capability of human body.
While there have been shown and described what are at present considered the fundamental principles and essential features of the invention and its advantages, it will be apparent to those skilled in the art that the invention is not limited to the details of the foregoing exemplary embodiments, but is capable of other specific forms without departing from the spirit or essential characteristics thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (7)
1. The formula of the Mitoq antioxidant hard capsule is characterized in that: comprises the following raw materials in parts by weight: 10-30 mg of Mitoq molecules; 100-200 mg of vitamin E in parts by mass; astaxanthin accounts for 40-60 mg by mass; 40-60 mg of microcrystalline cellulose.
2. The Mitoq antioxidant hard capsule formulation of claim 1, wherein: comprises the following raw materials in parts by weight: the mass part of the Mitoq molecule is 10 mg; vitamin E100mg in parts by mass; astaxanthin accounts for 40mg in parts by mass; the microcrystalline cellulose content was 40mg parts by mass.
3. The Mitoq antioxidant hard capsule formulation of claim 1, wherein: comprises the following raw materials in parts by weight: 20mg of mitoxantrone hydrochloride; vitamin E150mg in parts by mass; 50mg of astaxanthin in parts by mass; the microcrystalline cellulose content was 50mg by mass.
4. The process for preparing the Mitoq antioxidant hard capsule formulation of claim 1, wherein: the preparation steps are as follows:
a. weighing the raw materials in parts by weight;
b. after the step a is finished, putting Mitoq, vitamin E, astaxanthin and microcrystalline cellulose into a mixer, and uniformly mixing to obtain the content of the prepared capsule;
c. after the step b is finished, putting the raw materials of the empty capsules into a mixing machine for mixing, then carrying out sol, glue dipping, drying, shell pulling, cutting and finishing on the mixed raw materials to prepare the empty capsules, filling capsule contents into half of the empty capsules, and then sleeving half of the empty capsules with the filled empty capsules;
d. after the step c is finished, pressing the sleeved capsule by using a pressing machine, and cleaning medicinal powder attached to the outer part of the capsule shell to obtain a hard capsule;
e. and d, finishing, weight detecting and packaging the prepared hard capsule after the step d is finished.
5. The process for preparing the Mitoq antioxidant hard capsule formulation according to claim 4, wherein: and b, the rotating speed of the mixer in the step b is 750-900 r/min during mixing, and the mixing time is 20-40 min.
6. The process for preparing the Mitoq antioxidant hard capsule formulation according to claim 4, wherein: the capsule shell in the step c is mainly prepared from the following raw materials: gelatin, plasticizer, glycerin, sodium carboxymethylcellulose, thickener, opacifier, colorant, and preservative.
7. The process for preparing the Mitoq antioxidant hard capsule formulation according to claim 4, wherein: and e, performing weight detection on the prepared hard capsule in the step e, wherein the weight of the hard capsule is 0.5 g/capsule.
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| CN202210008655.8A CN114344274A (en) | 2022-01-05 | 2022-01-05 | Mitoq antioxidant hard capsule formula and preparation process |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115089693A (en) * | 2022-07-14 | 2022-09-23 | 盖茨汉普(武汉)植物应用研究有限公司 | A kind of Mitoq Hugan Hard Capsules formula and preparation technology |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103764132A (en) * | 2011-06-03 | 2014-04-30 | 米托特克公司 | Oral formulations of mitochondrially-targeted antioxidants and their preparation and use |
| CN104705650A (en) * | 2013-12-13 | 2015-06-17 | 于新华 | Coenzyme Q10 containing health food |
| CN106617028A (en) * | 2016-12-02 | 2017-05-10 | 芜湖市诺康生物科技有限公司 | Coenzyme Q10 capsule and preparation method thereof |
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2022
- 2022-01-05 CN CN202210008655.8A patent/CN114344274A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103764132A (en) * | 2011-06-03 | 2014-04-30 | 米托特克公司 | Oral formulations of mitochondrially-targeted antioxidants and their preparation and use |
| CN104705650A (en) * | 2013-12-13 | 2015-06-17 | 于新华 | Coenzyme Q10 containing health food |
| CN106617028A (en) * | 2016-12-02 | 2017-05-10 | 芜湖市诺康生物科技有限公司 | Coenzyme Q10 capsule and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115089693A (en) * | 2022-07-14 | 2022-09-23 | 盖茨汉普(武汉)植物应用研究有限公司 | A kind of Mitoq Hugan Hard Capsules formula and preparation technology |
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Application publication date: 20220415 |