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CN114053986B - Pre-packaged reagent containers for centrifugally controlled sequential mixing reactions - Google Patents

Pre-packaged reagent containers for centrifugally controlled sequential mixing reactions Download PDF

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Publication number
CN114053986B
CN114053986B CN202111500269.2A CN202111500269A CN114053986B CN 114053986 B CN114053986 B CN 114053986B CN 202111500269 A CN202111500269 A CN 202111500269A CN 114053986 B CN114053986 B CN 114053986B
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reagent
container
reagents
reagent container
wall
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CN202111500269.2A
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CN114053986A (en
Inventor
何艺
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Hangzhou Vocational and Technical College
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Hangzhou Vocational and Technical College
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/28Moving reactors, e.g. rotary drums

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

The invention relates to a reagent pre-packaging container capable of centrifugally controlling sequential mixing reaction, wherein a plurality of reagent chambers with different heights are sequentially arranged on the inner wall of the reagent container, reagents are pre-added in the reagent chambers, different chemical reagents are isolated by pre-adding the reagents in the reagent chambers which are sequentially arranged, a proper amount of reagents are added in the reagent container, a driving force is applied to the reagent container through a mixing device, the chemical reagents in the reagent chambers and the chemical reagents in the reagent container are controlled to be mixed in sequence from far to near according to a rotating shaft, the pre-packaging of the reagents in the reagent container reduces the time of manual material distribution and preparation, and the sequential mixing of the reagents in the reagent container is controlled, so that the experimental efficiency is improved, and the sequential mixing and the automation of the reactions of the different reagents are realized.

Description

Reagent pre-packaging container capable of centrifugally controlling sequential mixing reaction
Technical Field
The invention relates to a reagent packaging container, in particular to a reagent pre-packaging container capable of centrifugally controlling sequential mixing reaction.
Background
The chemical reagent is a relative standard substance for chemical research and component analysis, is widely used for synthesis, separation, qualitative and quantitative analysis of substances, can be said to be eyes of chemical workers, is not separated from the chemical reagent in daily works of factories, schools, laboratories and research institutions, and is widely applied to various industries of industry, agriculture, medical health, life science, inspection and quarantine, environmental protection, energy development, national defense and military industry, scientific research and national economy.
In the process of the preparation and reaction of the chemical reagents, the chemical reagents are applied to the mixing device, the chemical reagents are stirred in the mixing device, so that the chemical reagents in the mixing device are fully mixed and reacted to form a certain chemical raw material required by people, however, the mixing reaction device for a large laboratory needs to perform equal mixing reaction on two different chemical reagents before mixing, in the prior art, the two chemical reagents added into the mixing reaction device are subjected to material distribution and preparation basically through manual operation, the time of manual material distribution and preparation is too long, the experimental efficiency is reduced, and the automation of mixing of different reagents is not facilitated.
Disclosure of Invention
In order to solve the above problems, the present invention provides a reagent pre-packaging container for a centrifugally controlled sequential mixing reaction in which reagents are pre-packaged in the container and sequential mixing of the reagents is controlled according to the reaction requirements.
In order to achieve the above purpose, the reagent pre-packaging container capable of centrifugally controlling sequential mixing reaction designed by the invention mainly comprises a reagent container, wherein a reagent chamber higher than the bottom of the reagent container is arranged in the reagent container. This structure controls the reaction sequence of the chemical reagent in the reagent chamber with the chemical reagent at the bottom of the reagent container by providing the reagent chamber in the reagent container.
Further, the inside of the reagent container is respectively provided with a plurality of reagent chambers with different heights. The structure sets different reagent chambers at different heights so as to respectively distinguish different types of chemical reagents, and when the centrifugal driving force is provided for the reagent container through the mixing device, the sequence of the reaction is controlled according to the sequence that the reagents are far from the centrifugal rotating shaft.
In a further scheme, an L-shaped cavity wall extends on the inner wall of the reagent container, the L-shaped cavity wall and the inner wall of the reagent container are matched to form a reagent chamber, a semi-closed cavity cover which is obliquely close to the inner wall of the reagent container extends on the upper part of the L-shaped cavity wall, and a gap position for a reaction reagent to flow out when a reaction occurs exists between the semi-closed cavity cover and the inner wall of the reagent container. The structure is characterized in that the reagent chamber is fixedly arranged on the inner wall of the reagent container, the reagent is prevented from flowing out of the reagent chamber before being mixed by the semi-closed chamber cover, and meanwhile, the flowing direction of the reagent can be further optimized by the semi-closed chamber cover.
In a further scheme, a sealing cover is arranged at the top of the reagent container, and a drying reagent pad is arranged on the surface facing the inside of the reagent container. The structure prevents reagent from being thrown out of the container during the mixing reaction through the arrangement of the sealing cover, and the drying reagent is arranged in the sealing cover, so that the same effect as the reagent chamber is achieved, and two different chemical reagents are distinguished.
In a further scheme, the reagent chamber is internally added with a reagent. The structure reduces the time of manual material distribution and allocation by adding the reagent into the reagent chamber, thereby improving the experimental efficiency and realizing the automation of reagent mixing.
The invention designs a reagent pre-packaging container capable of centrifugally controlling sequential mixing reaction, wherein a plurality of reagent chambers with different heights are sequentially arranged on the inner wall of the reagent container, reagents are pre-added in the reagent chambers, different chemical reagents are isolated by pre-adding the reagents in the reagent chambers which are sequentially arranged, and after a proper amount of reagents are added in the reagent containers, a driving force is applied to the reagent containers through a mixing device, so that the chemical reagents in the reagent chambers and the reagent containers are controlled to be mixed in sequence from far to near from a centrifugal rotating shaft of the mixing device, and the pre-packaging time of manual material distribution and allocation is reduced in the reagent containers, thereby improving experimental efficiency, controlling the sequential mixing of the reagents in the reagent containers, and realizing the automation of sequential mixing of different reagents.
Drawings
FIG. 1 is an isometric view of a reagent pre-package container that can centrifugally control sequential mixing reactions.
FIG. 2 is a cross-sectional view of a reagent pre-packaging container for a centrifugally controlled sequential mixing reaction.
FIG. 3 is a schematic illustration of the use of a reagent pre-package container for centrifugally controlled sequential mixing reactions.
Detailed Description
In order to further describe the technical means and effects adopted by the present invention for achieving the intended purpose, the following detailed description will refer to the specific implementation, structure, characteristics and effects according to the present invention with reference to the accompanying drawings and preferred embodiments.
Example 1.
As shown in fig. 1 and fig. 2, the reagent pre-packaging container capable of centrifugally controlling sequential mixing reaction described in this embodiment mainly includes a reagent container 1, a reagent chamber 2 higher than the bottom of the reagent container 1 is disposed in the reagent container 1, and two reagent chambers 2 with different heights are sequentially disposed on the inner wall of the reagent container 1.
The inner wall of the reagent container 1 is extended with an L-shaped cavity wall 4, the L-shaped cavity wall 4 is matched with the inner wall of the reagent container 1 to form a reagent chamber 2, the upper part of the L-shaped cavity wall 4 is extended with a semi-closed cavity cover 5 which is obliquely close to the inner wall of the reagent container 1, a gap position for the reaction reagent 3 to flow out when the reaction occurs exists between the semi-closed cavity cover 5 and the inner wall of the reagent container 1, and the reagent is pre-added in the reagent chamber 2.
The top of the reagent container 1 is provided with a sealing cover 7, and the lower bottom surface of the sealing cover 7 is provided with a drying reagent pad 6.
As shown in FIG. 3, the reagent pre-packaging container for centrifugally controlling sequential mixing reaction is used as follows:
Sample reagent is added at the bottom of the reagent container 1, and simultaneously, reaction reagents are sequentially added in the reagent chamber 2 arranged on the inner wall of the reagent container 1 from low to high according to the reagent mixing sequence;
the reagent container 1 is installed and fixed in a mixing device, and the mixing device drives the reagent container 1 to rotate;
the rotation of the reagent container drives the sample reagent in the reagent container 1 to shift upwards to the reagent chamber 2;
So that the sample reagent in the reagent vessel 1 and the reaction reagent 3 in the reagent chamber 2 are mixed in this order from the far side to the near side with respect to the rotation axis 8.
The present invention is not limited in any way by the above-described preferred embodiments, but is not limited to the above-described preferred embodiments, and any person skilled in the art will appreciate that the present invention can be embodied in the form of a program for carrying out the method of the present invention, while the above disclosure is directed to equivalent embodiments capable of being modified or altered in some ways, it is apparent that any modifications, equivalent variations and alterations made to the above embodiments according to the technical principles of the present invention fall within the scope of the present invention.

Claims (2)

1.一种可离心控制顺序混合反应的试剂预封装容器,主要包括试剂容器(1),其特征在于所述的试剂容器(1)内设有高于试剂容器(1)底部且高度不同的两个试剂腔室(2);所述的试剂容器(1)内壁上延伸有L型腔壁(4),L型腔壁(4)与试剂容器(1)内壁配合组成试剂腔室(2),L型腔壁(4)上部延伸有斜向靠近试剂容器(1)内壁的半闭合腔盖(5),所述的半闭合腔盖(5)与试剂容器(1)内壁之间存有在发生反应时供反应试剂(3)流出的间隙位;所述的试剂容器(1)顶部设有密封盖(7),密封盖(7)面向试剂容器(1)内部的表面上设有干化试剂垫(6)。1. A reagent pre-packaged container capable of centrifugally controlling a sequential mixing reaction, mainly comprising a reagent container (1), characterized in that the reagent container (1) is provided with two reagent chambers (2) which are higher than the bottom of the reagent container (1) and have different heights; an L-shaped cavity wall (4) extends from the inner wall of the reagent container (1), the L-shaped cavity wall (4) cooperates with the inner wall of the reagent container (1) to form the reagent chamber (2), a semi-closed cavity cover (5) extending from the upper part of the L-shaped cavity wall (4) and close to the inner wall of the reagent container (1), a gap is present between the semi-closed cavity cover (5) and the inner wall of the reagent container (1) for the reaction reagent (3) to flow out when a reaction occurs; a sealing cover (7) is provided on the top of the reagent container (1), and a drying reagent pad (6) is provided on the surface of the sealing cover (7) facing the inside of the reagent container (1). 2.根据权利要求1所述的可离心控制顺序混合反应的试剂预封装容器,其特征在于所述的试剂腔室(2)内添加有试剂。2. The reagent pre-packaged container capable of centrifugally controlling sequential mixing reactions according to claim 1, characterized in that reagents are added into the reagent chamber (2).
CN202111500269.2A 2021-12-09 2021-12-09 Pre-packaged reagent containers for centrifugally controlled sequential mixing reactions Active CN114053986B (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN217699213U (en) * 2021-12-09 2022-11-01 杭州职业技术学院 Reagent prepackaged containers for controlled sequential mixing reactions by centrifugation

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PL237582B1 (en) * 2015-09-15 2021-05-04 Spark Tech Spolka Z Ograniczona Odpowiedzialnoscia Insert and method for separation of fluids, using the density gradient
US10585021B2 (en) * 2016-08-11 2020-03-10 Instrumentation Laboratory Company Dual chamber reagent mixing container
KR102090503B1 (en) * 2018-03-12 2020-03-18 계명대학교 산학협력단 Sample mixing equipment
CN210449543U (en) * 2019-07-16 2020-05-05 深圳市第二人民医院 Prevent centrifuging tube subassembly of vibration when taking out

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN217699213U (en) * 2021-12-09 2022-11-01 杭州职业技术学院 Reagent prepackaged containers for controlled sequential mixing reactions by centrifugation

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