CN114052912B - A neurosurgery ultrasound navigation drainage system - Google Patents
A neurosurgery ultrasound navigation drainage system Download PDFInfo
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
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- A—HUMAN NECESSITIES
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- A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
- A61B8/4483—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer
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- A—HUMAN NECESSITIES
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- A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0464—Cerebrospinal fluid
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Abstract
The neurosurgery ultrasonic navigation drainage system comprises a drainage tube, an ultrasonic probe, a host, a display, a wire, a connecting tube and a drainage container. The drainage tube is connected with the ultrasonic probe, the host is used for processing signals detected by the ultrasonic probe, and the display is used for displaying images and data processed by the host. The invention is used for the neurosurgery skull minimally invasive surgery, can display the brain tissue structure and the distribution of hydrocephalus in real time in the surgery, correct brain displacement images, monitor the blood supply pipelines of glioma, and guide drainage in the surgery and after the surgery.
Description
Technical Field
The invention relates to the field of neurosurgery, in particular to an ultrasonic navigation drainage system for neurosurgery.
Background
With the continuous development of a plurality of technologies such as modern optical technology, electronic technology, space navigation technology and the like, fluorescence microscopy, fluorescence radiography, intraoperative CT and MRI, intraoperative ultrasonic and electromagnetic nerve navigation technology and the like are developed and applied to clinic, so that the precise neurosurgery concepts of accurate positioning, minimum trauma and highest excision rate are deeper into the heart of people. Accurate positioning and intra-operative real-time monitoring are key to determining whether surgery can be successful. However, the requirements of CT, MRI, and fluoroscopic imaging are high in the environment, space, and facilities of the operating room, and the nerve navigation is susceptible to the drift of brain tissue during the operation, and errors occur. In addition, the ultrasonic wave can not cause harm to human body, has no radiation, and can diagnose and treat for many times.
Because of the continuous updating of the instrument, the method is simple and convenient, the report is rapid, the diagnosis accuracy is improved year by year, and the clinic replaces some traditional diagnosis methods. The basic principle is as follows: the ultrasonic wave propagates in human body, and the ultrasonic wave generates physical characteristics such as reflection, refraction, scattering, diffraction, attenuation at interfaces of two different tissues and Doppler frequency shift generated by the relative motion of a sound source and a receiver due to the acoustic characteristic difference of various tissues of the human body. The method is characterized in that different types of ultrasonic diagnostic instruments are applied, various scanning methods are adopted to receive the reflection and scattering signals, various tissues and pathological changes of the tissues are displayed, different reflection rules are combined with pathology and clinical medicine, and the pathological change positions, the properties and the degree of dysfunction are diagnosed by observation, analysis and summarization. In the process of operation, the traditional nerve navigation system which relies on preoperative positioning is difficult to accurately position due to the gradually aggravated brain tissue displacement. Brain tissue displacement is also known as image postbrain tissue distortion or brain tissue deformation. The brain tissue displacement is caused by various reasons, such as brain tissue swelling, cerebrospinal fluid loss, bone flap removal, dura mater opening, brain tissue traction, lesions or brain tissue excision, lesion cyst fluid release, dehydrating agent and anesthetic use, mechanical ventilation, gravity influence and the like.
The prognosis of operation of a patient is related to a plurality of factors, after neurosurgery craniocerebral operation, most of the patient needs to be placed with a drainage tube to drain blood, effusion or cerebrospinal fluid after the operation so as to relieve cerebral edema, the positions of the blood and the effusion can be confirmed through a neurosurgery ultrasonic navigation drainage system, the anchor point of the drainage tube is confirmed, and the postoperative drainage rehabilitation process of the patient is improved.
In order to locate brain tissue displacement and improve patient prognosis in neurosurgery, an ultrasonic nerve navigation system SomoWand is marketed in Norway, which needs to be assisted with other locators to achieve the navigational positioning function of neurosurgery. The siemens's ACUSON sequoia 5.12 color ultrasonic diagnostic apparatus is generally used for imaging of abdomen, chest, cardiovascular and other parts, and is not used for intraoperative and postoperative drainage.
Patent CN112040873a discloses an ultrasound imaging system, which focuses on protecting the control panel, and is not relevant to neurosurgical ultrasound navigation drainage systems. Patent CN108577968a discloses a craniotomy robot based on ultrasonic waves, which does not relate to the aspects of ultrasonic area array probes, ultrasonic imaging depth, ultrasonic working modes, ultrasonic data processing modes, ultrasonic control modes, ultrasonic imaging modes and the like.
The general neurosurgery navigation system uses optical or electromagnetic navigation, and is required to be matched with an ultrasonic instrument for use in neurosurgery operation, so that the system is complicated. In view of the above-mentioned drawbacks of the prior art, the present invention aims to develop a neurosurgery ultrasonic navigation drainage system for guiding and positioning in real time after operation in order to solve the problem of positioning errors caused by postoperative brain tissue displacement.
Disclosure of Invention
The invention develops the neurosurgery ultrasonic navigation drainage system, integrates the functions of positioning, imaging and real-time ultrasonic guiding, and facilitates positioning and drainage in and after operation. In addition, the cerebral hydrops positioning and the drainage tube 1 navigation are more convenient and faster, the treatment effect is improved, and the safety of patients is protected.
In order to achieve the above purpose, the invention provides a neurosurgical ultrasonic navigation drainage system, which comprises a drainage tube, an ultrasonic probe, a host, a display, a lead, a connecting tube and a drainage container. The ultrasonic probe is arranged at the bottom and the side face of the proximal end of the drainage tube, the host is used for processing signals detected by the ultrasonic probe, and the display is used for displaying images and data processed by the host. The drainage tube is provided with a guide wire, a drainage hole, a developing wire, a guide wire, a connecting pipe and a drainage bag, wherein the guide wire is positioned in the tube wall of the drainage tube, one section of the guide wire is connected with an ultrasonic probe, and the other section of the guide wire extends to the distal end of the drainage tube and is led out of the tube; the drainage hole is positioned at the proximal end of the drainage tube, the developing line is positioned on the wall of the drainage tube the direction is consistent with the direction of the tube body of the drainage tube, the guide wire is positioned in the drainage tube and is movable. The ultrasonic probe comprises a ring-shaped phased probe at the bottom and a convex array probe at the side. The annular phased probe can adjust the ultrasonic emission frequency in the frequency range of 0.5-10MHz, and the ultrasonic probe can be switched between the normal ultrasonic and Doppler pulse modes of operation. The invention is used for neurosurgery, can display the brain tissue structure and the distribution of hydrocephalus in real time in the operation, correct brain displacement images, monitor the blood supply pipeline of glioma and guide drainage in the operation and after the operation.
The neurosurgery ultrasonic navigation drainage system has the following technical effects:
1. The neurosurgery ultrasonic navigation drainage system provided by the invention is provided with a miniaturized ultrasonic probe, and can safely and conveniently enter an opening to image the internal tissues, lesions and blood vessels of the cranium in real time;
2. The neurosurgery ultrasonic navigation drainage system can carry out approach navigation on the drainage tube. The probe works at low frequency when in access, ultrasonic signals are transmitted to a brain tissue and hydrocephalus interface through air to generate echoes, hydrocephalus is confirmed by the echo signals, and the drainage tube is guided into the hydrocephalus;
3. The ultrasonic probes at the bottom and the side of the neurosurgery ultrasonic navigation drainage system can perform full-angle real-time imaging, perform real-time imaging in operation or after operation, and compare and confirm images after brain tissue displacement so as to solve the influence of the brain tissue displacement on the operation;
4. The bottom of the drainage tube of the neurosurgery ultrasonic navigation drainage system is made of polyethylene or polypropylene, the polyethylene or polypropylene bottom is used as a matching layer of an ultrasonic probe, the difference between the acoustic resistance and the acoustic resistance of tissues is small, the reflectivity of ultrasonic waves at an interface is small, the loss of signals transmitted to cerebral hydrops can be reduced, and the imaging quality is improved.
The conception, specific structure, and technical effects of the present invention will be further described with reference to the drawings and specific examples to fully understand the objects, features, and effects of the present invention.
Drawings
Fig. 1 is a schematic diagram of signal processing of an ultrasonic navigation drainage system for neurosurgery.
Fig. 2 is a drainage schematic diagram of the neurosurgery ultrasonic navigation drainage system, which comprises a drainage tube 1, an ultrasonic probe 2, a host computer 3, a display 4, a lead 5, a connecting tube 6 and a drainage bag 7.
Fig. 3 is a diagram of an ultrasonic ring-shaped phased probe transducer piezoelectric crystal design, including a center circular piezoelectric crystal 8, a first stage ring-shaped piezoelectric crystal 9, a second stage ring-shaped piezoelectric crystal 10, and a third stage ring-shaped piezoelectric crystal 11.
Fig. 4 is a graph of ultrasound frequency versus probe depth and resolution magnitude in brain tissue.
Examples
The present invention will be described in detail with reference to the accompanying drawings. It is to be understood, however, that the drawings are designed solely for the purposes of providing a better understanding of the invention and are not to be construed as limiting the invention. In the description of the present invention, it is to be understood that the terminology is for the purpose of description only and is not to be interpreted as indicating or implying relative importance.
Example 1
The drainage tube 1 of the neurosurgery ultrasonic navigation drainage system is made of polyurethane through mould pressing, the length is 1500mm, the diameter is 8mm, the connecting tube 6 is made of latex materials through extrusion, the length is 2000mm, and the drainage container 7 is made of polyethylene through extrusion to form a grenade-type container with the capacity of 200 ml. The ultrasonic probe 2 is made of polypropylene material with low acoustic resistance by injection molding to form an ultrasonic probe 2 shell, electrodes are sequentially arranged on the upper surface and the lower surface of a piezoelectric crystal 8-11, the piezoelectric crystal is arranged on a flexible printed circuit board and then glued into the shell, sound absorbing materials are further arranged in the shell, finally, a lead 5 is connected and then assembled on the drainage tube 1, and the lead 5 is led out.
In the neurosurgery craniocerebral minimally invasive surgery, the preparation stage needs to be connected with the components of the drainage tube 1, the ultrasonic probe 2, the host computer 3, the display 4, the lead 5, the connecting tube 6 and the drainage container 7 of the neurosurgery ultrasonic navigation drainage system in advance.
The drainage tube 1 is sent into the skull minimally invasive surgery opening in fig. 2 through a guide wire, and enters an ultrasonic guiding stage. In this stage, the ultrasonic signals of the ultrasonic probe 2 are transmitted into the brain through the air, the frequency of the annular phased ultrasonic probe 2 at the bottom of the ultrasonic probe 2 is adjusted to a low-frequency working mode of 0.5MHz as the ultrasonic signals with higher frequency attenuate in the air, and the ultrasonic signals have different reflectivities at the air/hydrocephalus interface, the air/cerebral tissue interface and the air/skull interface due to the existence of acoustic resistance, the positions of hydrocephalus, cerebral tissue and skull are confirmed through ultrasonic echo, and the drainage tube 1 is guided to safely and accurately enter hydrocephalus.
After entering hydrocephalus, the ultrasonic probe 2 enters an ultrasonic real-time imaging stage, for deep large-size lesions, according to a relation diagram of ultrasonic frequency, detection depth and resolution in brain tissues of FIG. 4, the effective detection depth of the annular phased ultrasonic probe 2 at the bottom of the ultrasonic probe 2 on tissues at the frequency of 0.5MHz is 14cm, but the resolution of imaging is lower, about 1.5mm, and the resolution of lesion tissues is weaker. The ultrasonic frequency of the ultrasonic probe 2 is increased to 10MHz, the imaging resolution can be increased to 0.1mm, the image resolution can be improved, and the imaging is clearer. The annular phased ultrasonic probe 2 at the bottom of the ultrasonic probe 2 scans the brain in real time when the frequency of the annular phased ultrasonic probe 2 is modulated to 0.5MHz, the host computer 3 receives the scanning signal and displays a 3D image of the brain after processing, and the brain tissue displacement, the position of pathological changes in the brain and the distribution of hydrocephalus are confirmed in real time. Compared with the CT/MIR image, the method guides the neurosurgeon to perform the operation, and avoids the operation accidents caused by brain tissue drifting. The drainage tube 1 is guided to be placed at the bottom of the hydrocephalus so as to ensure sufficient drainage, the hydrocephalus is led out through the drainage tube 1, and the hydrocephalus flows through the connecting tube 6 to be stored in a grenade-type container.
Example 2
The drainage tube 1 of the neurosurgery ultrasonic navigation drainage system is pressed by silicon rubber, the length is 1000mm, the diameter is 6mm, the connecting tube 6 is extruded by latex materials, the length is 1500mm, and the drainage container 7 is extruded by polyethylene to form a grenade container with the capacity of 150 ml. The ultrasonic probe 2 is made of polypropylene material with low acoustic resistance by injection molding to form an ultrasonic probe 2 shell, electrodes are sequentially arranged on the upper surface and the lower surface of a piezoelectric crystal 8-11, the piezoelectric crystal is arranged on a flexible printed circuit board and then glued into the shell, sound absorbing materials are further arranged in the shell, finally, a lead 5 is connected and then assembled on the drainage tube 1, and the lead 5 is led out.
In the neurosurgery craniocerebral minimally invasive surgery, the preparation stage and the ultrasonic guiding stage are the same as those of the embodiment 1, in the ultrasonic real-time imaging stage, for shallow small-size lesions, the annular phased ultrasonic probe 2 at the bottom of the ultrasonic probe 2 scans the brain in real time at the frequency of 10MHz, after the host computer 3 receives scanning signal processing, the 3D image of the brain is displayed by the display 4, and the brain tissue displacement, the position of the lesions in the brain and the distribution of hydrocephalus are confirmed in real time. Compared with the CT/MIR image, the method guides the neurosurgeon to perform the operation, and avoids the operation accidents caused by brain tissue drifting. The drainage tube 1 is guided to be placed at the bottom of the hydrocephalus so as to ensure sufficient drainage, the hydrocephalus is led out through the drainage tube 1, and the hydrocephalus flows through the connecting tube 6 to be stored in a grenade-type container.
Example 3
The drainage tube 1 of the neurosurgery ultrasonic navigation drainage system is made of polyurethane through mould pressing, the length is 500mm, the diameter is 4mm, the connecting tube 6 is made of latex materials through extrusion, the length is 1200mm, and the drainage container 7 is made of polyvinyl chloride through mould pressing to form a spring container with the capacity of 100 ml. The ultrasonic probe 2 is made of polypropylene material with low acoustic resistance by injection molding to form an ultrasonic probe 2 shell, electrodes are sequentially arranged on the upper surface and the lower surface of a piezoelectric crystal 8-11, the piezoelectric crystal is arranged on a flexible printed circuit board and then glued into the shell, sound absorbing materials are further arranged in the shell, finally, a lead 5 is connected and then assembled on the drainage tube 1, and the lead 5 is led out.
In the neurosurgery craniocerebral minimally invasive surgery, the preparation stage and the ultrasonic guiding stage are the same as those of the embodiment 1, in the ultrasonic real-time imaging stage, the convex array ultrasonic probe 2 on the side face of the ultrasonic probe 2 scans the brain in real time, after the host computer 3 receives scanning signal processing, the 3D image of the brain is displayed by the display 4, and the brain tissue displacement, the position of the pathological changes in the brain and the distribution of cerebral effusion are confirmed in real time. Compared with the CT/MIR image, the method guides the neurosurgeon to perform the operation, and avoids the operation accidents caused by brain tissue drifting. The drainage tube 1 is guided to be placed at the bottom of the hydrocephalus so as to ensure sufficient drainage, the hydrocephalus is led out through the drainage tube 1, and the hydrocephalus flows through the connecting tube 6 to be stored in the spring type container.
Example 4
The drainage tube 1 of the neurosurgery ultrasonic navigation drainage system is made of silicon rubber through die pressing, the length is 200mm, the diameter is 2mm, the connecting tube 6 is made of silicon rubber through extrusion, the length is 1000mm, and the drainage container 7 is made of polyvinyl chloride through die pressing to form a spring container with the capacity of 50 ml. The ultrasonic probe 2 is made of polypropylene material with low acoustic resistance by injection molding to form an ultrasonic probe 2 shell, electrodes are sequentially arranged on the upper surface and the lower surface of a piezoelectric crystal 8-11, the piezoelectric crystal is arranged on a flexible printed circuit board and then glued into the shell, sound absorbing materials are further arranged in the shell, finally, a lead 5 is connected and then assembled on the drainage tube 1, and the lead 5 is led out.
In the neurosurgery craniocerebral minimally invasive surgery, the preparation stage and the ultrasonic guiding stage are the same as those of the embodiment 1, and in the ultrasonic real-time imaging stage, when pathological tissues are processed, the annular phased ultrasonic probe 2 at the bottom of the ultrasonic probe 2 starts a Doppler ultrasonic mode to scan the brain in real time, after the host computer 3 receives the scanning signal processing, the 3D image of the brain and the vascular position of the pathological tissues are displayed by the display 4, and the brain tissue displacement, the pathological positions in the brain and the distribution of cerebral effusion are confirmed in real time. Compared with the CT/MIR image, the method guides the neurosurgeon to perform the operation, and avoids the operation accidents caused by brain tissue drifting and vascular rupture. The drainage tube 1 is guided to be placed at the bottom of the hydrocephalus so as to ensure sufficient drainage, the hydrocephalus is led out through the drainage tube 1, and the hydrocephalus flows through the connecting tube 6 to be stored in the spring type container.
Comparative example 1
The simple cerebral drainage tube can not accurately guide drainage under the condition of no ultrasonic probe 2, and can not observe the positions of brain tissue, hydrocephalus and pathological tissues in the brain, and the life safety of patients is easily endangered when the operation is performed under the condition of brain displacement.
Comparative example 2
In the neurosurgery ultrasonic navigation drainage system, under the condition that the ultrasonic probe 2 does not have a side convex array ultrasonic probe, an image of pathological tissues with deflection angles cannot be observed, and ultrasonic real-time navigation cannot be performed during operation.
Comparative example 3
In the neurosurgery ultrasonic navigation drainage system, when the impedance of the matching layer material of the ultrasonic probe 2 is not matched with the impedance of cerebral hydrops, the loss of ultrasonic signals is high, and the definition of ultrasonic real-time imaging is reduced.
It is noted that the above embodiments are only for illustrating the embodiments of the present application, and not for limiting the scope of the present application, and it is possible for a person skilled in the art to make modifications or equivalents of the present application without departing from the spirit and scope of the application, and any modifications or partial substitutions are intended to be covered by the scope of the claims of the present application.
Claims (5)
1. An ultrasonic navigation drainage system for neurosurgery, which is characterized in that: comprises a drainage tube, an ultrasonic probe, a host, a display, a wire, a connecting tube and a drainage container; the ultrasonic probe consists of an annular phased ultrasonic probe arranged at the bottom of the proximal end of the drainage tube and a convex array ultrasonic probe arranged on the side face of the drainage tube, wherein the ultrasonic frequency is pulse ultrasonic waves of 0.5-10MHz, and imaging resolution ratios of lesions with different depths and angles are adjusted by controlling the frequency of the ultrasonic probe so as to complete the full-angle real-time imaging of the brain; the transducer piezoelectric crystal of the annular phase control ultrasonic probe comprises a central circular piezoelectric crystal, a first-stage annular piezoelectric crystal, a second-stage annular piezoelectric crystal and a third-stage annular piezoelectric crystal; the drainage tube is provided with a guide wire matched with the drainage tube, the drainage tube is made of silicon rubber or polyurethane materials, the drainage tube is provided with drainage holes, scales and a wire channel, the length of the tube body is 200-1500mm, the diameter is 2-8mm, the drainage holes are arranged at the proximal end of the tube body of the drainage tube, 3 pairs of round holes with the diameter of 1mm are arranged in 30mm of the proximal end of the drainage tube, and the wire channel is reserved in the tube wall of the drainage tube.
2. The neurosurgical ultrasound navigation drainage system according to claim 1, wherein the guide wire is located in the wall of the drainage tube, one end of the guide wire is connected with the ultrasound probe, and the other end extends out of the distal end of the drainage tube to be connected with the host.
3. The neurosurgical ultrasound navigation drainage system according to claim 1, wherein the connecting tube is hollow in a hose shape with a length of 1000-2000mm, and is made of one or more of silicone rubber, silica gel, latex, polyethylene, polyvinyl chloride, and polypropylene materials, and is used for connecting the drainage tube and the drainage container.
4. The neurosurgical ultrasound navigation drainage system according to claim 1, wherein the drainage container is made of polyvinyl chloride or silica gel material, and the container is a negative pressure drainage, and is classified as a grenade container or a spring container, and has a capacity of 50-200ml.
5. The neurosurgical ultrasound navigation drainage system of claim 1, wherein the guide wire is made of stainless steel material, the guide wire being positioned within the drainage tube and moveable.
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