Stem cell cryopreserving device
Technical Field
The invention relates to the technical field of stem cell preservation, in particular to the technical field of stem cell cryopreservation equipment.
Background
Stem cell cryopreservation equipment is medical equipment used for freezing and storing stem cells, and in the conventional stem cell preservation, a stem cell bag is usually placed in a cryopreservation box, a plurality of cryopreservation boxes are placed in a cryopreservation box, and then the cryopreservation box is placed in a liquid nitrogen tank for preservation.
The existing freezing storage box is generally provided with a drawer type structure, although a large number of freezing storage boxes can be placed in the freezing storage box, the drawer is of a sliding structure, the drawer is easy to slide and collide when a frame body is transferred, the freezing storage boxes are easy to shake and scatter out, and frozen stem cells are easy to damage due to the fact that no buffering structure is arranged when the freezing storage boxes are collided; and the cryopreservation box is placed in the cryopreservation box, is not fixed, and is easy to shake, so that the position of the cryopreservation box is easy to change, and the cryopreservation effect of stem cells is influenced.
Therefore, there is a need for an improved stem cell cryopreservation device that overcomes the aforementioned problems.
Disclosure of Invention
The invention aims to: in order to solve the technical problems, the invention provides a stem cell cryopreservation device.
The invention specifically adopts the following technical scheme for realizing the purpose:
the utility model provides a stem cell cryopreserving device, includes cryopreserved case body and cryopreserved case body inside sliding connection's cryopreserved frame body with cryopreserved, cryopreserved has seted up a plurality of standing grooves on the frame body, the standing groove inner wall is connected with splint through the elastic buffer post, cryopreserved case is originally internal still to rotate and is connected with the screw rod, be provided with opposite direction's screw thread on the screw rod, the cover is equipped with threaded sleeve respectively on opposite direction's the screw thread, threaded sleeve passes through the connecting rod and cryopreserved frame body rear portion and is connected, the both ends of connecting rod articulate respectively at threaded sleeve and cryopreserved frame body rear portion, cryopreserved is equipped with a sealed tip on the frame body, sealed tip with cryopreserved case body magnetism is connected.
Preferably, the freezing frame body is connected with the left inner wall and the right inner wall of the freezing box body in a sliding mode through sliding connection pieces, each sliding connection piece comprises balls arranged on two sides of the freezing frame body and sliding grooves arranged on the left inner wall and the right inner wall of the freezing box body, and the balls slide in the sliding grooves.
Preferably, the elastic buffer column comprises a first connecting column, a through groove, a spring and a second connecting column, the first connecting column is fixed on the inner wall of the placing groove, the through groove is formed in the first connecting column, the second connecting column is fixed on the outer side surface of the clamping plate, and the second connecting column is connected with the bottom in the through groove through the spring.
Preferably, one side that the threaded sleeve kept away from the freezing frame body is equipped with the slider, the inboard at freezing case body back is provided with the slide rail, slider sliding connection on the slide rail.
Preferably, the sealing end portion is provided with an iron sheet, the freezing storage box body is provided with a magnet, and the magnet arranged on the freezing storage box body and the iron sheet arranged at the sealing end portion are attracted magnetically.
Preferably, the front surface of the freezing and storing frame body is provided with a hinged seat, the hinged seat is rotatably connected with a lock rod through a rotating shaft, the side surface of the freezing and storing box body is provided with a lock ring, and the lock rod is matched with the lock ring to realize locking.
Preferably, the lock ring is provided with a lock hole, the lock rod is L-shaped, and the end part of the lock rod is clamped into the lock hole to realize locking.
Preferably, the bottom surface in the placing groove is provided with a layer of non-slip mat.
Preferably, the inner side of the splint is provided with a layer of cushion pad.
Preferably, foot pads are arranged at four corners of the bottom of the freezing and storing box body.
The invention has the following beneficial effects:
1. according to the invention, the screw rod, the threaded sleeve and other structures are connected on the cryopreservation frame body, so that the cryopreservation frame body can be pushed out and pulled back without manual pulling, and the phenomenon that the cryopreservation frame body shakes to damage the cryopreserved stem cells due to uneven force applied by manual operation is avoided.
2. According to the invention, the sealing end part on the freezing frame body is magnetically connected with the freezing box body, so that the freezing frame body can be prevented from sliding and colliding during transfer through the magnetic attraction effect after being pushed into the freezing box body, the freezing frame body can be kept stable, and the displacement is avoided.
3. The freezing storage box can be clamped and fixed by arranging the clamping plates in the placing groove, the placing stability is improved, and the clamping plates are fixed on the inner wall of the placing groove through the elastic buffer columns, so that the elastic buffer columns can buffer and slow down shaking, the force acting on the freezing storage box is reduced, and the freezing storage box is protected.
4. According to the invention, the slide rail and the slide block are matched, so that the threaded sleeve can be assisted to move left and right on the screw rod, the movement of the threaded sleeve is further limited, the movement of the threaded sleeve is more stable, and the shaking generated when the freezing storage rack body is pushed out and pulled back is reduced.
5. According to the invention, the locking rod and the locking ring which are matched for use are arranged on the surface of the cryopreservation rack body and the side surface of the cryopreservation box body, the locking rod is rotated downwards, the end part of the locking rod is downwards inserted into the locking hole arranged on the locking ring, so that the locking ring and the locking ring are locked, the cryopreservation rack body is fixed, the phenomenon that the cryopreservation rack body slides out due to movement or collision is avoided, and the damage to the cryopreserved stem cells in the cryopreservation rack body is avoided.
6. According to the invention, the anti-slip mat is arranged on the inner bottom surface of the placing groove, so that on one hand, the anti-slip effect can be achieved on the cryopreservation box placed in the placing groove, the cryopreservation box is prevented from moving, on the other hand, the buffering and shock absorption effect can be achieved, and the bottom of the cryopreservation box is protected.
7. According to the invention, the buffer pads are arranged on the inner side surfaces of the clamping plates, so that the clamping plates can be prevented from being in direct contact with the freezing box, the freezing box is prevented from being damaged by the clamping plates, and an elastic buffer effect can be formed between the clamping plates and the freezing box, so that the side surfaces of the freezing box are protected.
Drawings
FIG. 1 is a schematic front view of the present invention;
FIG. 2 is a schematic side view of the present invention;
FIG. 3 is a schematic top view of the cryopreservation rack body;
fig. 4 is a schematic top view of the placement tray;
FIG. 5 is an enlarged view of a portion of the invention at A in FIG. 4;
FIG. 6 is a schematic side view of the placement tray;
reference numerals: 1-cryopreservation box body, 2-cryopreservation rack body, 201-sealed end, 3-sliding connector, 301-ball, 302-chute, 4-motor, 5-screw, 6-connecting rod, 7-threaded sleeve, 8-sliding rail, 9-sliding block, 10-placing groove, 11-cryopreservation box, 12-magnet, 13-iron sheet, 14-clamping plate, 15-elastic buffer column, 151-first connecting column, 152-through groove, 153-spring, 154-second connecting column, 16-buffer pad, 17-hinged seat, 18-rotating shaft, 19-locking ring, 20-locking rod, 21-foot pad and 22-non-slip pad.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
As shown in fig. 1 to 6, a stem cell cryopreserving device, including cryopreserving case body 1 and cryopreserving case body 1 inside sliding connection's cryopreserving frame body 2 with cryopreserving, cryopreserving has seted up a plurality of standing grooves 10 on the frame body 2, standing groove 10 inner wall is connected with splint 14 through elastic buffer post 15, it is connected with screw rod 5 still to rotate in the case body 1 to cryopreserve, screw rod 5 one end is connected with the output of motor 4, be provided with opposite direction's screw thread on the screw rod 5, the cover is equipped with threaded sleeve 7 on the opposite direction's screw thread respectively, threaded sleeve 7 is connected with cryopreserving frame body 2 rear portion through connecting rod 6, the both ends of connecting rod 6 articulate respectively at threaded sleeve 7 and cryopreserving frame body 2 rear portion, cryopreserving is equipped with a seal end 201 on the frame body 2, seal end 201 is connected with cryopreserving case body 1 magnetism.
When using, pack into the cryopreserved box 11 with the stem cell of treating cryopreserving earlier, then put into cryopreserved box 11 and freeze the standing groove 10 that sets up on the frame body 2, because cryopreserved frame body 2 and cryopreserved 1 inner wall sliding connection of case body, after placing, rotate through screw rod 5, make two threaded sleeve 7 remove on screw rod 5, two threaded sleeve 7 are close to each other, can pull back cryopreserved frame body 2 to cryopreserved case body 1 in through articulated connecting rod 6, thereby make cryopreserved frame body 2 get back to cryopreserved case body 1 in, realize sealedly, realize the release and the pull back of cryopreserved frame body 2 through the effect of screw rod 5 and threaded sleeve 7, do not need artificial pulling, avoid the artificial force of applying of operation inhomogeneous, lead to cryopreserved frame body 2 to take place to rock, cause the damage to the stem cell of cryopreserving.
In addition, because the sealed tip 201 that sets up on the cryopreserving frame body 2 is connected with cryopreserving case body 1 magnetism, after cryopreserving frame body 2 pushed into cryopreserving case body 1 inside, through the magnetic attraction effect, can prevent that cryopreserving frame body 2 from taking place to slide and collide when shifting, make cryopreserving frame body 2 can remain stable, avoid taking place the aversion.
Simultaneously, after putting into standing groove 10 freezing and depositing box 11, can be fixed freezing and depositing 11 centre grippings of box through splint 14, improve the stability of placing, and because splint 14 fixes at the 10 inner walls of standing groove through elastic buffer post 15, elastic buffer post 15 set up can play the buffering to rocking and slow down the effect, make to use the power of freezing and depositing box 11 to reduce, play the guard action to freezing and depositing box 11.
Example 2
This embodiment is further preferred on embodiment 1's basis, two sides of freezing frame body 2 pass through sliding connection 3 and two inner wall sliding connection about freezing case body 1, sliding connection 3 is including establishing ball 301 in freezing frame body 2 both sides and establishing the spout 302 at two inner walls about freezing case body 1, ball 301 slides in spout 302. Through the structure that sets up ball 301 and spout 302, can realize freezing the slip of depositing frame body 2, during the slip, ball 301 rolls in rail spout 302, can reduce the resistance of freezing frame body 2 when releasing and withdrawing.
Example 3
This embodiment is further preferable on the basis of embodiment 1, the elastic buffer column 15 includes a first connecting column 151, a through groove 152, a spring 153 and a second connecting column 154, the first connecting column 151 is fixed on the inner wall of the placing groove 10, the through groove 152 is opened on the first connecting column 151, the second connecting column 154 is fixed on the outer side surface of the clamping plate 14, and the second connecting column 154 is connected with the bottom in the through groove 152 through the spring 153.
When taking place to rock or collide, standing groove 10 receives the influence of power for first spliced pole 151 extrudees spring 153, thereby make spring 153 between first spliced pole 151 and the second spliced pole 154 produce deformation, make first spliced pole 151 and second spliced pole 154 produce relative displacement, utilize the deformation of spring 153 to cushion power, after the impact force disappears, spring 153 resumes original position, thereby it plays the effect of buffer protection to deposit box 11 to freezing of centre gripping.
Example 4
The embodiment is further preferable on the basis of embodiment 1, one side of the threaded sleeve 7, which is far away from the cryopreservation rack body 2, is provided with a slide block 9, the inner side of the back of the cryopreservation box body 1 is provided with a slide rail 8, and the slide block 9 is connected on the slide rail 8 in a sliding manner. Through setting up slide rail 8 and the cooperation of slider 9, can assist threaded sleeve 7 and remove about moving on screw rod 5, further play limiting displacement to threaded sleeve 7's removal, make threaded sleeve 7's removal more stable, reduce and freeze rocking that deposits frame body 2 produced when release and pull back.
Example 5
In this embodiment, it is further preferable that the sealing end portion 201 is provided with an iron piece 13, the freezing box body 1 is provided with a magnet 12, and the magnet 12 provided on the freezing box body 1 is magnetically attracted to the iron piece 13 provided on the sealing end portion 201. Through setting up magnet 12 and iron sheet 13, both produce the appeal, deposit a body 2 and pull back to freezing and deposit 1 inside backs of case body when freezing, through magnet 12 and iron sheet 13's attraction, can make freezing and deposit a body 2 more stable, prevent to remove or cause freezing and deposit a body 2 and take place to slide when meetting the collision.
Example 6
In this embodiment, it is further preferable that on the basis of embodiment 1, a hinged seat 17 is disposed on the front surface of the cryopreservation rack body 2, a lock rod 20 is rotatably connected to the hinged seat 17 through a rotating shaft 18, a lock ring 19 is disposed on the side surface of the cryopreservation box body 1, and the lock rod 20 and the lock ring 19 are matched to realize locking; the lock ring 19 is provided with a lock hole, the lock rod 20 is L-shaped, and the end part of the lock rod 20 is clamped into the lock hole to realize locking.
After the freezing frame body 2 returns to the inside of the freezing box body 1, the locking rod 20 is rotated to rotate downwards, the end part of the locking rod 20 is downwards inserted into the locking hole formed in the locking ring 19, the locking ring 19 and the locking rod 20 are locked, and therefore the freezing frame body 2 is fixed, the freezing frame body 2 is prevented from sliding out due to movement or collision, and damage to the frozen stem cells inside is avoided.
Example 7
This embodiment is further preferred on the basis of embodiment 1, as preferred, the bottom surface is provided with one deck slipmat 22 in standing groove 10, splint 14 medial surface is provided with one deck blotter 16, the four corners department in the bottom of the freezing case body 1 is provided with callus on the sole 21, specifically, slipmat 22, blotter 16 and callus on the sole 21 all adopt rubber material, utilize the elastic force of rubber to play the guard action.
The anti-slip mat 22 can prevent the freezing box 11 placed in the placing groove 10 from slipping on one hand and prevent the freezing box 11 from moving on the other hand, and can play a role in buffering and damping on the other hand and protect the bottom of the freezing box 11; the cushion pad 16 can prevent the clamp plate 14 from directly contacting the cryopreservation box 11 and prevent the clamp plate 14 from damaging the cryopreservation box 11, and can form an elastic buffer effect between the clamp plate 14 and the cryopreservation box 11 to protect the side surface of the cryopreservation box 11; the foot pad 21 that cryopreserved case body 1 bottom set up can make and cryopreserved case body 1 and ground between form certain space, reinforcing air permeability, also play anti-skidding effect simultaneously.