CN113786557A - Minimally invasive electrical stimulation system - Google Patents
Minimally invasive electrical stimulation system Download PDFInfo
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- CN113786557A CN113786557A CN202111151131.6A CN202111151131A CN113786557A CN 113786557 A CN113786557 A CN 113786557A CN 202111151131 A CN202111151131 A CN 202111151131A CN 113786557 A CN113786557 A CN 113786557A
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Abstract
The application belongs to the technical field of medical instruments, and particularly relates to a minimally invasive electrical stimulation system which comprises a passive implant and a wireless stimulator, wherein the passive implant comprises a stimulation electrode, an ear side, a lead and a wireless receiving coil, the stimulation electrode is connected with the wireless receiving coil through the lead, and the ear side is arranged on the lead close to one side of the stimulation electrode; the wireless stimulator comprises a wireless transmitting coil, a battery, a main control chip, a communication module, a power adjusting module and a frequency adjusting module, wherein the main control chip, the communication module, the power adjusting module and the frequency adjusting module are arranged on a PCB (printed circuit board), the power adjusting module and the frequency adjusting module are both in electric signal connection with the main control chip, the power adjusting module and the frequency adjusting module are both adjusted through a wave wheel button, and the main control chip is in electric signal connection with the wireless transmitting coil through the communication module; the battery is connected with the PCB circuit board circuit, and the wireless stimulator is also provided with a charging interface for charging the battery. This application adopts passive implanted electric stimulation mode, has both reached the purpose of accurate regulation and control stimulation dosage, has solved the problem of battery again simultaneously.
Description
Technical Field
The application belongs to the technical field of medical instruments, and particularly relates to a minimally invasive electrical stimulation system.
Background
A weak and appropriate amount of electrical stimulation can improve or treat some adverse symptoms of human body, and conventional electrical stimulation is divided into in vitro electrical stimulation and implanted electrical stimulation. The external electrical stimulation has small damage, is convenient and safe in the regulation and control process, does not excessively consider the problem of battery power, but the stimulation electrode and the target tissue have skin and other tissue intervals in the stimulation scheme, so that the current cannot be accurately released to a target area, and the effect is greatly weakened. The implantable electric stimulation implants the stimulation electrode and the whole stimulation module into the body by containing the battery, the electrode is also in direct contact with the target tissue, the stimulation dosage can be accurately regulated and controlled, and the treatment effect is achieved.
Disclosure of Invention
In order to solve the technical problems, the application provides a minimally invasive electrical stimulation system, wherein a stimulation electrode in a passive implant is attached and wrapped at a nerve position through an operation, and a wireless receiving coil (with inductance of 10 muH) is embedded under the cortex or in tissues through extension of a lead. The wireless stimulator with the parameter adjusted is attached on the cortex above the wireless receiving coil (inductance value 10 mu H) through magic tape or adhesive tape, the switch of the wireless stimulator is opened, the wireless stimulator starts to work, and the wireless stimulator is taken down to charge after the completion.
The application is realized by the following technical scheme: a minimally invasive electrical stimulation system comprises a passive implant and a wireless stimulator, wherein the passive implant comprises a stimulation electrode, an ear, a lead and a wireless receiving coil (inductance 10 mu H), the stimulation electrode is connected with the wireless receiving coil (inductance 10 mu H) through the lead, an ear bank is arranged on the lead close to two sides of the stimulation electrode and used for fixing the passive implant, and the wireless receiving coil (inductance 10 mu H) is used for receiving signals sent by the wireless stimulator; the wireless stimulator comprises a wireless transmitting coil (inductance 10 muH), a battery, a main control chip, a communication module, a power adjusting module and a frequency adjusting module, wherein the main control chip, the communication module, the power adjusting module and the frequency adjusting module are arranged on a PCB (printed circuit board), the power adjusting module and the frequency adjusting module are in electric signal connection with the main control chip, the power adjusting module and the frequency adjusting module are adjusted through a wave wheel button, and the main control chip is in electric signal connection with the wireless transmitting coil (inductance 10 muH) through the communication module; the battery is connected with the PCB circuit board electricity, still is equipped with the interface that charges for battery charging on the wireless stimulator.
Furthermore, a magnetic separation sheet is arranged between the PCB and the wireless transmitting coil (inductance value is 10 muH).
Furthermore, the wireless stimulator is also provided with a frequency modulation/amplitude modulation indicator light.
Furthermore, the stimulating electrode comprises an electrode tube, a longitudinal seam is arranged on the electrode tube, and suture lines are arranged on two sides of the longitudinal seam of the electrode tube; the stimulating electrode circuit is distributed on the inner pipe wall of the electrode pipe.
Further, the passive implant is entirely encased by an insulating layer, exposed only at the stimulation contacts of the stimulation electrodes.
Further, the wireless stimulator is attached to the skin over the passive implant by an adhesive structure.
Further, the charging interface adopts a Type-c interface.
The beneficial effect of this application is: the passive implant and the wireless stimulator carry out signal transmission in a resonance mode, an internal power supply is not needed to be arranged on the passive implant, the design is miniaturized, and the injury to a body after the passive implant is implanted is reduced. This application adopts passive implanted electric stimulation mode, has both reached the purpose of accurate regulation and control stimulation dosage, has solved the problem of battery again simultaneously.
Drawings
FIG. 1 is a schematic diagram of the operation of the present application;
FIG. 2 is a schematic view of a wireless implant according to the present application implanted in tissue;
FIG. 3 is a schematic diagram of a stimulation electrode of the present application;
FIG. 4 is a schematic structural diagram of a wireless stimulator according to the present application;
in the figure, 1, vagus nerve, 2, passive implant, 2.1, stimulating electrode, 2.11, electrode tube, 2.12, longitudinal seam, 2.13, suture line, 2.2, ear side, 2.3, lead, 2.4, wireless receiving coil, 3, wireless stimulator, 3.1, frequency modulation indicating lamp, 3.2, wave wheel button, 3.3, wireless transmitting coil, 3.4, magnetic isolation sheet, 3.5, battery, 3.6, PCB circuit board, 3.7 and charging interface.
Detailed Description
The present application is further described with reference to the following drawings and specific examples.
The electrical stimulation system of the present application may be used to stimulate nerves, blood vessels, or other tissues to alleviate or treat adverse conditions in a patient, or to stimulate a damaged nerve to induce its regeneration, or to stimulate the vagus nerve to treat hemiplegia, epilepsy, and to treat depression, diabetes, parkinson, alzheimer's disease, cardiovascular diseases, and the like.
In this example, hemiparalysis is treated by stimulating the vagus nerve. The vagus nerve is the nerve with the longest stroke and the widest distribution range in the cranial nerves, and comprises four fibers of somatic movement, somatic sensation, visceral movement and visceral sensation. Hemiplegia is a disease in which sensory and motor functions of one side of the body are lost due to dysfunction of the brain caused by injury to the nerves of the brain caused by trauma or disease. By stimulating the release of vagal neurotransmitters using an electrical stimulation system, neural circuits in certain regions of the brain are reactivated, allowing the ability to learn motor to be reestablished.
As shown in fig. 1 to 4, the electrical stimulation system comprises a passive implant 2 and a wireless stimulator 3, wherein the passive implant 2 comprises a stimulation electrode 2.1, an ear 2.2, a lead 2.3 and a wireless receiving coil 2.4 (inductance 10 muh). The stimulating electrode 2.1 comprises an electrode tube 2.11, a longitudinal seam 2.12 is arranged on the electrode tube 2.11, and suture lines 2.13 are arranged on the electrode tube 2.11 at two sides of the longitudinal seam 2.12; the stimulation electrode circuits are distributed over the inner tube wall of the electrode tube 2.11. The stimulating electrode circuit of the stimulating electrode 2.1 is connected with the wireless receiving coil 2.4 (inductance 10 muH) through a lead 2.3, the ear 2.2 is arranged on the lead 2.3 close to one side of the stimulating electrode 2.1, and the wireless receiving coil 2.4 (inductance 10 muH) receives the stimulating energy emitted by the wireless stimulator 3 through the electromagnetic induction principle. The passive implant 2 is entirely surrounded by an insulating layer, exposed only at the stimulation contacts of said stimulation electrode 2.1.
The passive implant 2 has good biocompatibility, can be used for embedding stimulation in a body for a long time, can also be made of an easily-absorbable material, does not need secondary operation after the treatment period is finished, and reduces the pain of a patient. The conductive circuit part of the implant can be made of stainless steel, titanium/titanium alloy, copper (or gold-plated copper), platinum, iridium/iridium oxide, platinum-iridium alloy, Pedot, gold, carbon/graphene, silver/silver chloride, other alloys and other conductive materials, or can be made of absorbable conductive materials, such as magnesium and magnesium alloy, and the manufacturing process can be completed by adopting the processes of winding displacement, etching, sputtering, printing and the like, the insulating layer is mainly made of flexible materials, including Polyimide (PI), Parylene, Polydimethylsiloxane (PDMS), Polyurethane (PU), silica gel, silicon rubber and other biocompatible flexible film materials, or can be made of absorbable high polymer materials, such as collagen, chitin, cellulose, polyamino acid, polyesters (such as polylactic acid and polyglycolic acid), novel hydrogel coatings (such as PEG-DMA and collagen), Or bioabsorbable polymers (PVA and PLGA, etc., also including composite materials (combinations of two or more different materials).
As shown in fig. 4 (a) and 4 (b), the wireless stimulator 3 includes a wireless transmitting coil 3.3 (inductance 10 μ H), a battery 3.5, and an STM32F103C8T6 main control chip, a communication module, a power adjusting module and a frequency adjusting module, which are disposed on a PCB 3.6, wherein the power adjusting module and the frequency adjusting module are electrically connected to the STM32F103C8T6 main control chip, and the power adjusting module and the frequency adjusting module are adjusted by a pulsator button 3.2, and the frequency of stimulation and the magnitude of stimulation current are adjusted by a pulsator button 3.2. The STM32F103C8T6 main control chip is in electrical signal connection with a wireless transmitting coil 3.3 (inductance 10 muH) through a communication module; battery 3.5 is connected with PCB circuit board 3.6 electricity, still is equipped with the interface 3.7 that charges for battery 3.5 on the wireless stimulator 3, and the interface 3.7 that charges adopts the commonly used Type-c interface on the market at present. The whole device of the wireless stimulator 3 adopts the light weight and low power consumption design, the shell adopts the aluminum-magnesium alloy, and the device is light, thin, good in protectiveness, not easy to wear, beneficial to heat dissipation, convenient to carry and capable of performing intermittent stimulation training for a long time.
As a modification of this embodiment, a magnetic separation sheet 3.4 is disposed between the PCB circuit board 3.6 and the wireless transmitting coil 3.3 (inductance 10 μ H). The magnetism isolating piece 3.4 enables electromagnetic energy to be concentrated on one hand, and shields the wireless transmitting coil 3.3 (inductance 10 mu H) and a circuit on the PCB circuit board 3.6 on the other hand, so that crosstalk is reduced, and the magnetism isolating piece 3.4 mainly comprises materials such as ferrite, amorphous, nanocrystalline and the like.
As shown in fig. 4 (a), the wireless stimulator 3 is further provided with a frequency/amplitude modulation indicator light 3.1, and the operating mode of the stimulator and the magnitude of the stimulation current are determined by the indicator light.
The application method comprises the following steps: the stimulation electrode 2.1 in the passive implant 2 is attached and wrapped at the vagus nerve 1 on the neck through an operation, specifically, the diameter of the inner tube of the electrode tube 2.11 and the diameter of the vagus nerve 1 are close to or slightly larger than the diameter of the vagus nerve 1, the vagus nerve 1 is embedded in the electrode tube 2.11 through a longitudinal seam 2.12 in the operation, and the electrode tube 2.11 is fastened and closed through a suture 2.13 on the electrode tube 2.11, so that the vagus nerve 1 can be ensured to be tightly attached to the electrode contact, and the stimulation signal can be limited on the vagus nerve 1. The wireless receiving coil 2.4 (inductance 10 muH) is embedded under the skin or in the tissue of the shoulder by the extension of the wire 2.3. The wireless stimulator 3 with adjusted parameters is attached to the skin above the wireless receiving coil 2.4 (inductance 10 muH) through a magic tape or a glue tape, a switch of the wireless stimulator is turned on, the wireless stimulator starts to work, the STM32F103C8T6 main control chip transmits the set frequency and power to the wireless transmitting coil 3.3 (inductance 10 muH) through the communication module information, and transmits the set frequency and power to the wireless receiving coil 2.4 (inductance 10 muH) of the passive implant 2 in a resonance mode, so that the stimulating current is transmitted to the stimulating electrode, and the function of the nervous system is adjusted and the function of tissue repair is promoted through stimulating vagus nerve; and after the wireless stimulator is finished, the wireless stimulator is taken down for charging. The device can be used for long-term nerve rehabilitation training and can perform intermittent stimulation training according to self conditions at regular time. In order to prevent the passive implant 2 from being interfered by other electromagnetic signals when not working at ordinary times, the passive implant 2 can be wrapped with an electromagnetic shielding layer mainly made of metal, carbon or other conductive materials after the user completes stimulation training.
It should be apparent that the above-described embodiments are only some of the embodiments of the present application, and those skilled in the art should not make any inventive changes to the present application without departing from the spirit of the present invention.
Claims (7)
1. A minimally invasive electrical stimulation system comprises a passive implant (2) and a wireless stimulator (3), wherein the passive implant (2) comprises a stimulation electrode (2.1), an ear side (2.2), a lead (2.3) and a wireless receiving coil (2.4), the stimulation electrode (2.1) is connected with the wireless receiving coil (2.4) through the lead (2.3), the ear side (2.2) is arranged on the lead (2.3) close to one side of the stimulation electrode (2.1), and the wireless receiving coil (2.4) is used for receiving signals sent by the wireless stimulator (3); the method is characterized in that: the wireless stimulator (3) comprises a wireless transmitting coil (3.3), a battery (3.5), a main control chip, a communication module, a power adjusting module and a frequency adjusting module, wherein the main control chip, the communication module, the power adjusting module and the frequency adjusting module are arranged on a PCB (3.6), the power adjusting module and the frequency adjusting module are in electric signal connection with the main control chip, the power adjusting module and the frequency adjusting module are adjusted by a wave wheel button (3.2), and the main control chip is in electric signal connection with the wireless transmitting coil (3.3) through the communication module; battery (3.5) and PCB circuit board (3.6) circuit connection still are equipped with the interface (3.7) that charges for battery (3.5) on wireless stimulator (3).
2. The minimally invasive electrical stimulation system of claim 1, wherein: and a magnetism isolating sheet (3.4) is arranged between the PCB circuit board (3.6) and the wireless transmitting coil (3.3).
3. The minimally invasive electrical stimulation system of claim 1, wherein: the wireless stimulator (3) is also provided with a frequency modulation and amplitude modulation indicator light (3.1).
4. The minimally invasive electrical stimulation system of claim 1, wherein: the stimulation electrode (2.1) comprises an electrode tube (2.11), a longitudinal seam (2.12) is arranged on the electrode tube (2.11), and suture lines (2.13) are arranged on the electrode tube (2.11) at two sides of the longitudinal seam (2.12); the stimulation electrode circuits are distributed over the inner tube wall of the electrode tube (2.11).
5. A minimally invasive electrical stimulation system according to claim 1 or 4, characterized in that: the passive implant (2) is entirely surrounded by an insulating layer, exposed only at the stimulation contacts of the stimulation electrode (2.1).
6. The minimally invasive electrical stimulation system of claim 1, wherein: the wireless stimulator (3) is attached to the skin above the passive implant (2) through an adhesion structural member (4).
7. The minimally invasive electrical stimulation system of claim 1, wherein: the charging interface (3.7) adopts a Type-c interface.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111151131.6A CN113786557A (en) | 2021-09-29 | 2021-09-29 | Minimally invasive electrical stimulation system |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202111151131.6A CN113786557A (en) | 2021-09-29 | 2021-09-29 | Minimally invasive electrical stimulation system |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115177865A (en) * | 2022-07-22 | 2022-10-14 | 北京品驰医疗设备有限公司 | Spinal cord electrical stimulation system |
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2021
- 2021-09-29 CN CN202111151131.6A patent/CN113786557A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115177865A (en) * | 2022-07-22 | 2022-10-14 | 北京品驰医疗设备有限公司 | Spinal cord electrical stimulation system |
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