CN113712664B - Laser dot matrix intelligent skin physiotherapy instrument based on electroporation - Google Patents

Abstract

The invention provides a laser lattice intelligent skin physiotherapy instrument based on electroporation, comprising a physiotherapy probe, a cable and a host having a dep area, a lattice laser area and a drug delivery area, wherein the physiotherapy probe has a casing, One end of the casing is a physiotherapy end, and the other end is a cable lead-out end. The cable is connected to the host, so that the host can control the physiotherapy probe to perform skin physiotherapy, so that the LRT generated by dep can conduct laser energy transmission and avoid traditional lasers. Fractional trauma disadvantages, use the intelligent image recognition model to perform laser physiotherapy on the lesion site to achieve accurate coverage of the fractional laser, choose percutaneous drug delivery to give additional skin care effects on the basis of laser physiotherapy, and can freely choose traditional dep or laser Dot matrix single physiotherapy plan, or mixed physiotherapy mode, to achieve a variety of customized options for user physiotherapy plan.

Description

Laser dot matrix intelligent skin physiotherapy instrument based on electroporation

technical field

The invention relates to a laser lattice skin physiotherapy instrument, in particular to a laser lattice intelligent skin physiotherapy instrument based on electroporation and an intelligent physiotherapy method thereof, belonging to the field of skin physiotherapy instruments.

Background technique

Electroporation (dep) technology is a high-voltage pulse acting on the skin to generate a temporary reversible ion transport channel (LTR) in the stratum corneum of the skin, and achieve rapid and efficient skin care technology through simultaneous drug delivery. The laser lattice relies on the high-energy pulsed lattice laser to act on the skin to produce approximately linear microporous channels on the skin surface, so that the photons can penetrate deep into the dermis layer of the skin, resulting in thermal coagulation around the pores to form stable scattered through-holes. The heat energy is transferred around the through hole for subcutaneous pigment or blood vessels, disintegrates pigment spots and abnormally distributed microvessels, and dredges the microvessels to achieve beauty.

However, the through-hole produced by fractional laser is a kind of skin wound, which needs to undergo self-repair of skin cells, go through the stages of inflammatory proliferation and remodeling, and inevitably produce side effects and poor repair during the three processes, while the LTR generated by electroporation It belongs to a temporary ion hydrophilic channel. After opening, it is restored by rearrangement of stratum corneum cells for a period of time. It belongs to a real non-invasive technology.

From a technical point of view, the dot matrix laser changes the emission pattern through the image generator (CPG), forming a variety of geometric shapes to act on the skin. However, the parts of the skin surface that need to be repaired are often not fully covered by simple geometric figures. Some healthy parts do not require physiotherapy, but are usually also affected by laser microbeams, resulting in coverage errors. Therefore, the fractional laser cannot be targeted to select the parts that need physiotherapy for action.

In the prior art, penetration is promoted by ultrasonic introduction after fractional laser, but this combined technique only promotes the penetration of drugs, but does not have the physiotherapeutic effect of rapid freckle removal and melanin decomposition. Therefore, if the non-invasive nature of dep can be used, combined with the rapid thermal effect of the fractional laser, on the one hand, the drug can be administered quickly, and on the other hand, the pigmented spots in the skin can be effectively eliminated, and the multiple functions of nourishment, treatment and beauty can be achieved. Considering the size of the LTR hole (5-100μm) and the hole generated by the fractional laser (typically about 120μm), the latter covers the former, so if the laser can be introduced into the LTR around the site that needs physiotherapy, on the one hand, a thermal effect will be generated. At the same time, it can also take advantage of the temporary advantages of LTR to achieve non-invasive closure and recovery, and selectively cover the parts that need physiotherapy to generate fractional lasers to achieve real non-invasive smart skin physiotherapy.

SUMMARY OF THE INVENTION

In order to overcome the above-mentioned shortcomings of the prior art, the present invention considers three aspects, the selective generation of the first electroporation, how to select the part that needs physiotherapy for the second fractional laser, and the improvement of the energy of the laser. The third administration procedure.

To this end, the present invention provides an electroporation-based laser lattice intelligent skin physiotherapy instrument, comprising a physiotherapy probe, a cable and a host, wherein the physiotherapy probe has a casing, one end of the casing is a physiotherapy end, and the other end is a physiotherapy end. It is a cable outlet, and the cable is connected with the host, so that the host can control the physiotherapy probe to perform skin physiotherapy.

Further, the dep area, the fractional laser area, and the drug delivery area around or inside the dep area that the physiotherapy end has are respectively related to the dep cavity, the fractional laser cavity, and the drug delivery cavity formed by division in the outer shell. one end is connected;

A dep device is installed in the dep cavity, which is used to generate LTR by acting on the part in need of physiotherapy through the dep area;

The dep device has at least one three-dimensional dep probe protruding from the dep area, which is used to fit the skin to perform electric pulse action, preferably, voltage parameters: pulse frequency 1-2.5Hz, pulse voltage 25-200V;

A laser lattice module and a skin imaging device are installed in the lattice laser cavity, wherein the laser lattice module includes a laser with n×m laser rectangular lattice or multi-pixel circular laser lattice or multi-pixel other regular geometric shape lasers. A lattice control module of a lattice, the lattice control module is electrically connected to the skin imaging device, and is used to control the n×m laser lattice or multi-pixel circular laser spots according to the skin surface image transmitted by the skin imaging device Array or multi-pixel laser lattice with other regular geometric shapes is used for the part that needs physiotherapy; optionally, n and m are selected between 7-200. Laser parameters: power: ≤20W, laser working mode: including continuous mode, super pulse mode, intermittent mode, pulse energy: 1mJ-100mJ, energy interval 1.5-2mJ, focal spot diameter: 50μm-1000μm, pulse width: 0.1ms- 10ms

Optionally, the dot matrix control module includes an image acquisition module, an image processing module, and a dot matrix excitation module, wherein the image acquisition module is used to collect images captured by the skin imaging device, and the image processing module is used to The collected images are divided, the parts that need physiotherapy are identified, and control signals are generated, and the lattice excitation module controls the laser lattices in the parts requiring physiotherapy and/or nearby n×m laser lattices according to the control signals or multi-pixel circular laser lattice or multi-pixel laser lattice with other regular geometric shapes to emit pulsed laser to act on the part, so that the pulsed laser acts on the skin stratum corneum and the skin tissue below it at least partially through LTR, select Physically treat the skin.

The image processing module includes an image recognition unit and a control signal generation unit, the image recognition unit performs grayscale according to the collected image, divides the grayscale image into multiple regions to form multiple sub-images, and identifies each sub-image If g is less than the preset value, the area where the sub-image is located is used as the physiotherapy area, and the signal generating unit only generates a control signal according to the physiotherapy area in the gray-scaled image, and sends out the control signal, The control signal generating unit triggers the activation of the lattice excitation module according to the control signal of the physiotherapy area from which the control signal originates in the plurality of areas, so as to excite the laser lattice where the physiotherapy area is located to work to generate laser light and act on all the areas. the physiotherapy area;

Optionally, the preset value is the average value of the total grayscale values of the corresponding grayscale images of the images collected from at least one healthy skin area of the detection object, the average value is an arithmetic average value, and the weighted average value is either. The at least one healthy skin area may be determined according to the advice of the physiotherapist and/or user's choice.

It can be understood that when the benign skin lesions such as the color class are completely located in the sub-image area, complete coverage can be achieved, and the gray value is lower than when the same benign skin lesions are located in the sub-image area. And when the benign skin lesions are located in multiple sub-image areas, the gray value of each sub-image is smaller than the preset value, and all laser lattices in these sub-image areas need to be excited to Physiotherapy is performed on the area to achieve complete coverage of the benign skin lesion and its surrounding area, thereby achieving accurate coverage of the benign skin lesion as a whole.

In one embodiment, the image recognition unit further includes an intelligent image recognition unit, the intelligent image recognition unit establishes an artificial intelligence model according to the sub-image of the physiotherapy area of the grayscale image and the control signal, and the artificial The intelligent model identifies whether a control signal needs to be generated according to the sub-image, and the artificial intelligence model includes any one of a convolutional neural network CNN, a support vector machine SVM, and a generative adversarial network GAN, and the CNN is based on the sub-image. The corresponding control signal code, ie, 1 (generated) or 0 (not generated), can be identified, so as to identify whether each sub-image needs to generate a corresponding control signal. SVM is a classification algorithm that classifies multiple sub-images as control signal codes 1 or 0. GAN generates a pseudo grayscale image according to the randomly generated grayscale image and the preset value, and uses multiple sub-images to determine whether it belongs to the control signal code 1 or 0. After continuous correction, the pseudo grayscale image is close to the real multiple sub-images. The image sometimes identifies the correct code for it.

If the sub-image gray value is consistent with the position of the control signal identified by artificial intelligence, the former scheme is adopted; if it is inconsistent, one of the algorithms is adopted by the user through the host setting in advance, preferably the latter.

Preferably, the control signal generating unit includes a microprocessor or a single-chip microcomputer. The multiple regions are n×m multi-pixel matrix regions or multi-pixel circular laser lattices or multi-pixel other regular geometric figures.

Optionally, the skin imaging device is arranged in the lattice laser area or the lattice laser together with an n×m laser rectangular lattice or a multi-pixel circular laser lattice or a multi-pixel laser lattice with other regular geometric shapes. The other end of the cavity opposite to the lattice laser area, or between the two, and the skin imaging device is in an n×m laser rectangular lattice or a multi-pixel circular laser lattice or a multi-pixel laser lattice with other regular geometric shapes the geometric center position.

Preferably, the skin imaging device includes a camera and an illumination unit for illuminating the part, and the camera is preferably a high-definition pinhole camera.

Preferably, at least one of the dep area, the lattice laser area, and the drug delivery area around the dep area is formed of a transparent material as at least a part of the housing, more preferably, the lattice laser area is made of transparent material Material formation.

The drug delivery cavity is provided with a drug delivery device, which is used for drug delivery to LTR and/or LTR subjected to laser lattice action; preferably, the dep cavity and the drug delivery cavity are adjacent and sealed, and the three The periphery of the dep probe is provided with a drug delivery hole that communicates with the drug delivery device, so that the drug penetrates the skin through the drug delivery hole through the LTR and/or the LTR under the action of laser lattice for physical therapy.

The cable includes a first power line connected to the dep device, a first signal line that controls the operation of the dep device, a second power line connected to the laser dot matrix module and the skin imaging device, and a second power line that controls the operation of both. Two signal lines, a third power line connected to the drug delivery device and a third signal line for controlling the operation of the drug drug device, the first and third power lines are shielded and combined with the first and third signal lines, respectively. A first-third cable is formed, and the first-third cable is independently three cables.

The host includes a display screen, and three cable interfaces for connecting the first-third cable, which are used to control the dep device, the laser dot matrix module, the skin imaging device, the drug delivery device, and the parameter settings of the three. A processor that realizes intelligent skin physiotherapy by acquiring and analyzing physiotherapy data. The physiotherapy data includes images collected by the skin imaging device, user information and skin profile of each physiotherapy, physiotherapy process data (including dep, laser lattice, usage of each device for drug administration, and the parameters). The parameters are those well-known to those skilled in the art, such as voltage parameters, laser parameters, as well as the type of administration, speed, administration mode, continuous or pulsed form, and corresponding parameters.

Preferably, the main body further includes a moving bracket which facilitates moving the main body. Specifically, the moving bracket has a plurality of casters.

The present invention also provides an intelligent skin physiotherapy method based on an electroporation-based laser lattice intelligent skin physiotherapy instrument, characterized in that the method uses the above-mentioned electroporation-based laser lattice intelligent skin physiotherapy instrument, including:

(1) Select the desired physiotherapy mode: including the single dep physiotherapy mode, the single laser lattice physiotherapy mode, and the laser lattice physiotherapy mode based on electroporation, when the single dep physiotherapy mode and the single laser lattice physiotherapy mode are selected Then use the host to individually select the corresponding physiotherapy mode and use the physiotherapy probe to perform the corresponding physiotherapy, wherein the individual dep physiotherapy mode cooperates with the drug delivery device to control the drug delivery during or after the specified first time under the action of the electric pulse with the set parameters. The medicine device is used for drug administration, while the individual laser lattice physiotherapy mode completes the physiotherapy within a specified second time under the action of the laser pulses of the set laser parameters, or controls the drug delivery during or after the specified second time. The medicine device is used for administration; if the electroporation-based laser lattice hybrid physiotherapy mode is used, step (2) is entered; the first and second time are 1min-1h.

(2) First perform dep for the first time to generate LRT, and then use the laser lattice to perform the second time on the dep-acting area, the skin imaging device captures an image of the dep-acting area, and the laser lattice module quantifies the image of the dep-acting area. The region-selective physiotherapy of the dep effect, and then selectively perform step (3) according to the skin condition; preferably, the laser parameters of the laser lattice selected and used according to the needs are selected so as to not or to produce a straight-through dermis The laser parameters of the through hole of the layer.

Understandably, when laser parameters are chosen that do not produce through-holes, at least a portion of the laser beam is delivered to deeper skin layers through the LRT formed in and around benign lesions and converting energy into heat, resulting in Decomposes the physiotherapy effect of benign lesions, and does not produce perforation effect on the skin, so that LRT can basically restore the original state of the skin through reversible autism in a short time.

(3) The drug delivery device, which controls the selected parameters, performs drug administration on the skin area that has undergone dep and laser lattice physiotherapy for a third prescribed time to complete the physiotherapy, and the third time is 0.1 min-10 min.

Preferably, after the mixed physiotherapy mode is selected, the physiotherapy apparatus is prohibited from starting the drug delivery device to work during the dep action and the fractional laser action.

In one embodiment, after the first time of dep to generate LRT, before using the laser dot matrix to perform the second time to act on the dep-acting area, it further includes step (2-1): applying the drug delivery device to the dep-acting area. After the fourth time of penetration of photosensitizer in the area, and then applying physiological saline or medical alcohol to the action area through the drug delivery device to clean the residual photosensitizer, so that the fluorescent agent penetrated into the LRT can be captured by the fluorescent image captured by the skin imaging device, thereby Similarly, the control signal is generated through the aforementioned image division, grayscale, and sub-image grayscale total value calculation, or the aforementioned artificial intelligence model is used to identify the control signal for the grayscale image. In this way, the LRT falling within the sub-image area can be selectively irradiated with the pulsed laser light, so that at least part of the pulsed laser light can enter the LRT. The fourth time is 3-20s, the photosensitizer is a phytochrome, preferably, the phytochrome is chlorophyll.

The present invention also provides a non-transitory storage medium, which stores a computer-readable program that can be executed by the processor to implement the above-mentioned electroporation-based laser lattice intelligent skin physiotherapy method.

beneficial effect

(a) The LRT generated by dep is realized for laser energy conduction, which avoids the traumatic drawbacks of traditional laser lattices,

(b) Using the intelligent image recognition model to perform laser physiotherapy on the lesion to achieve error-free coverage of the fractional laser,

(c) Select transdermal administration to give additional skin care benefits on top of laser physiotherapy,

(d) Can freely choose traditional dep or laser dot matrix single physiotherapy plan, or mixed physiotherapy mode, to realize a variety of customized choices of user physiotherapy plan.

Description of drawings

Fig. 1. an embodiment of the laser lattice intelligent skin physiotherapy instrument based on electroporation of the present invention,

Figure 2. An embodiment of the structure of the physiotherapy probe of the present invention,

Figure 3. Schematic diagram of a 6×17 pixel skin image collected by grayscale of the present invention,

Figure 4. (a) and 4(b) before and after the mixed physiotherapy mode of the subject's facial physiotherapy before (a) and after (b) comparison effect graph,

Reference numeral 1 Laser lattice intelligent skin physiotherapy instrument based on electroporation, 2dep area, 3 lattice laser area, 4 drug delivery area, 5 7×16 laser rectangular lattice lattice control module, 6 camera, 7 illumination unit, 8 image acquisition module, 9 image processing module, 10 first cable, 11 second cable, 12 third cable, 13 mobile bracket, 14 casters, 21dep cavity, 31 lattice laser cavity, 41 drug delivery cavity , 211 stereo dep probe, 411 drug delivery holes.

Detailed ways

Example 1

As shown in FIG. 1, the electroporation-based laser lattice intelligent skin physiotherapy apparatus 1 of this embodiment includes a physiotherapy probe 1-0, a first cable 10, a second cable 11, and a third cable 12. Cable combination, and a host 1-1, wherein the physiotherapy probe 1-0 has a casing, one end of the casing is a physiotherapy end, and the other end is a lead end of the cable combination, the first cable 10, the second cable 11, and The third cable 12 is connected with the host 1-1, so that the host 1-1 can control the physiotherapy probe to perform skin physiotherapy.

As shown in FIG. 2, the physiotherapy end has a dep area 2, a lattice laser area 3, and a drug delivery area 4 inside the dep area 2, which are respectively connected with the divided dep cavity 21, the lattice laser cavity 31, and One end of the drug delivery cavity 41 communicates with each other; the lattice laser area 3 is formed of transparent organic glass.

A dep device is installed in the dep cavity 21, which is used to act on the site requiring physiotherapy through the dep zone 2 to generate LTR as shown in Figure 3;

The dep device has four three-dimensional dep probes 211 protruding from the dep area 2, which are used to fit the skin to perform electrical pulse action, voltage parameters: pulse frequency 2Hz, pulse voltage 100V;

A laser lattice module and a skin imaging device are installed in the lattice laser cavity 31, wherein the laser lattice module includes a 7×16 laser rectangular lattice lattice control module 5, and the skin imaging device further includes a camera 6 and a skin imaging device. The lighting unit 7 for illuminating the part, and the camera 6 is a high-definition pinhole camera.

The camera 6 and the 7×16 laser rectangular lattice are arranged at the other end of the lattice laser cavity opposite to the lattice laser area 3, and the camera 6 is at the center of the 7×16 laser rectangular lattice ( as shown in picture 2).

The lattice control module 5 is electrically connected with the skin imaging device, and is used to control the 7×16 laser rectangular lattice to perform the 7×16 laser rectangular lattice for the area that needs physiotherapy according to the skin surface image (as shown in FIG. 3 ) transmitted from the skin imaging device. Function; laser parameters: power: 15W, laser working mode: including continuous mode, super pulse mode, intermittent mode, pulse energy: 8mJ focal spot diameter: 120um, pulse width: 1ms.

The dot matrix control module 5 includes an image acquisition module 8, an image processing module 9, and a dot matrix excitation module (not shown), wherein the image acquisition module 8 is used to acquire the image captured by the camera 6, and the image processing The module 9 is used to divide the collected images, identify the parts that need physiotherapy, and generate control signals, and the lattice excitation module controls the 7×16 laser lattice in the parts that need physiotherapy and its vicinity according to the control signals The laser lattice in the device emits a pulsed laser to act on the site, so that the pulsed laser acts on the skin stratum corneum and the skin tissue below it at least partially through the LTR, and selectively performs physical therapy on the skin.

The image processing module 9 includes an image recognition unit and a control signal generation unit (not shown), the image recognition unit performs grayscale according to the collected image, and divides the grayscale image into multiple regions to form multiple sub-images (as shown in Figure 3), and identify the total gray value g in each sub-image. If g is less than the arithmetic mean of the total gray value of the corresponding gray-scaled image of the image collected from at least one healthy skin area, the area where the sub-image is located As a physiotherapy area, the signal generating unit only generates a control signal according to the physiotherapy area in the grayscaled image, and sends out a control signal, and the control signal generating unit generates a control signal in the plurality of areas according to the physiotherapy area from which the control signal originates. The coordinates in the lattice trigger the activation of the lattice excitation module, so as to excite the laser lattice work where the physiotherapy area is located to generate laser light to act on the physiotherapy area. The control signal generating unit is a single-chip microcomputer.

The dosing cavity 41 is provided with a dosing device for administering the LTR and the LTR subjected to the laser lattice action; the dep cavity 21 and the dosing cavity 41 are sealed with each other (not shown in the figure). The middle of the four stereo dep probes 211 has a drug delivery hole 411 that communicates with the drug delivery device, so that the drug penetrates the skin through the drug delivery hole through the LTR and the LTR under the action of laser lattice for physical therapy.

The host 1 includes a display screen 1-1-1, which is used to connect the first cable 10, the second cable 11, and the three cable interfaces of the third cable 12, and is used to control the dep device, laser The lattice module, the skin imaging device, the drug delivery device, the parameter setting of the three, and the acquisition and analysis of physiotherapy data, realize the processor (not shown in the figure) for intelligent skin physiotherapy.

The physiotherapy data includes images collected by the skin imaging device, user information and skin profile of each physiotherapy, physiotherapy process data, including dep, laser lattice, usage of each device for drug administration, and the parameters.

The host 1-1 also includes a moving bracket 13 that facilitates moving the main body. The moving bracket 13 has four casters 14 .

Example 2

The difference between this embodiment and Embodiment 1 lies in the aspect of image processing, wherein the image recognition unit includes an intelligent image recognition unit (not shown), and the intelligent image recognition unit is based on the sub-section of the physiotherapy area of the grayscale image. The image and the control signal establish an artificial intelligence model, the artificial intelligence model identifies whether a control signal needs to be generated according to the sub-image, the artificial intelligence model includes a convolutional neural network CNN, and the CNN can identify according to the sub-image The corresponding control signal code is 1 (generated) or 0 (not generated), so as to identify whether each sub-image needs to generate a corresponding control signal.

As shown in FIG. 3 , in the grayscaled image of the collected image in the dep selection process, it is exemplified that the four categories A, B, C, and D occupy different numbers (respectively 4, 2, 1 1, 3) color patches of sub-images, and the case of multiple LRT distributions distributed near the color patches and in sub-images without color patches. Due to the temporary reversible self-closing of the LRT, when the lattice laser uses the CNN model to intelligently identify a total of 10 sub-image areas in the four color spots according to the image to generate control signals, and excite the corresponding lattice to generate laser pulses with the set parameters, the laser part It can enter the LRT to generate heat accumulation and transfer it to the deep skin to decompose the pigmentation. According to the adjustment of the laser parameters, the LRT can continue to penetrate the inner layer of the skin deeply, resulting in a more effective decomposition effect. At the same time, there is no laser pulse effect in other sub-image areas. , the LRT is administered together with the LRT in the pigmented area to further protect the skin and achieve additional physiotherapy effects.

Example 3

Physiotherapy modes: including single dep physiotherapy mode, single laser lattice physiotherapy mode, and laser lattice physiotherapy mode based on electroporation. Selecting a corresponding physiotherapy mode and using the physiotherapy probe to perform the corresponding physiotherapy, wherein the individual dep physiotherapy mode cooperates with the drug delivery device to control the drug delivery device to perform drug delivery during or after the prescribed first time under the action of the electric pulse with the set parameters, In the single laser lattice physiotherapy mode, the physiotherapy is completed within a specified second time under the action of the laser pulses of the set laser parameters, or the drug delivery device is controlled to administer the drug during or after the specified second time; If the electroporation-based laser dot matrix hybrid physiotherapy mode is used, step (2) is entered; the first and second time are 1min-1h.

(2) First perform dep to generate LRT, and then use a laser lattice to act on the dep-acted area. The skin imaging device captures an image of the dep-acted area, and the laser lattice module selectively selects the dep-acted area. Physiotherapy, and then selectively perform step (3) according to the skin condition; preferably, the laser parameters selected by the laser lattice according to needs are selected as laser parameters that do not or will generate through holes through the dermis layer.

Understandably, when laser parameters are chosen that do not produce through-holes, at least a portion of the laser beam is delivered to deeper skin layers through the LRT formed in and around benign lesions and converting energy into heat, resulting in Decomposes the physiotherapy effect of benign lesions, and does not produce perforation effect on the skin, so that LRT can basically restore the original state of the skin through reversible autism in a short time.

(3) The drug delivery device, which controls the selected parameters, performs drug administration on the skin area that has undergone dep and laser lattice physiotherapy for a third prescribed time to complete the physiotherapy, and the third time is 0.1 min-10 min.

Example 4

An electroporation-based laser lattice intelligent skin physiotherapy method, characterized in that the method uses the electroporation-based laser lattice intelligent skin physiotherapy instrument of Embodiment 3, comprising:

(1) Select the desired physiotherapy mode: click and select the electroporation-based laser lattice hybrid physiotherapy mode on the screen 1-1-1 of the host 1-1, and then enter step (2);

(2) First perform 5min of dep to generate LRT, then use a 20min laser lattice to act on the dep-acted area, the camera 6 captures an image of the dep-acted area, and the laser lattice module 5 controls the dep-acted area Selective physiotherapy, then choose to carry out step (3) according to the skin condition; the laser parameters of the laser lattice selected and used according to the needs are selected as laser parameters that do not generate a large number of through holes directly through the dermis layer, that is, the pulse energy is in the dermis layer. Adjusted in 1-5mJ, the laser working mode is super pulse mode.

(3) The drug delivery device, which controls the selected parameters, penetrates the skin area that has undergone dep and laser lattice physiotherapy for a third prescribed period of time to complete the physiotherapy, and the third period is 0.5 min.

Figures 4(a) and 4(b) are the comparison results of the facial skin before and after (24 days) of physical therapy of the subjects taking the mixed treatment regimen. It can be seen that the results can effectively remove spots and whiten.

Example 5

On the basis of Example 4, after performing dep for the first time for 5 minutes to generate LRT, the present embodiment also includes step (2-1) before using the laser lattice to act on the area where dep acts for 20 minutes: passing the drug delivery device to the The chlorophyll alcohol solution is infiltrated into the action area for 20s, and then medical alcohol is applied to the drug delivery device for cleaning for 10-20s, so that the plant pigment infiltrated into the LRT can be captured by the fluorescent image captured by the skin imaging device, and the image collected by the camera 6 is also Division, grayscale, sub-image grayscale total value calculation and then generate control signals, or use CNN model to identify control signals for grayscale images, so the pulsed laser will only be irradiated in the sub-image area with LRT.

Claims (8)

1. The laser dot matrix intelligent skin physiotherapy instrument based on the electric pore forming is characterized by comprising a physiotherapy probe, a cable and a host, wherein the physiotherapy probe is provided with a shell, one end of the shell is a physiotherapy end, the other end of the shell is a cable leading-out end, and the cable is connected with the host so that the host can control the physiotherapy probe to carry out skin physiotherapy;

the dep area, the dot matrix laser area and the dosing area around or inside the dep area which are arranged at the physical therapy end are respectively communicated with one end of a dep cavity, a dot matrix laser cavity and a dosing cavity which are formed by cutting in the shell;

A dep device is arranged in the dep cavity and used for acting on a part needing physical therapy through a dep area to generate a temporary reversible ion transmission channel LTR;

the dep device is provided with at least one three-dimensional dep probe protruding out of the dep area and used for being attached to the skin to perform electric pulse action, and the voltage parameters are as follows: the pulse frequency is 1-2.5Hz, and the pulse voltage is 25-200V;

the laser dot matrix module comprises a dot matrix control module with an n x m laser rectangular dot matrix or a multi-pixel circular laser dot matrix or a multi-pixel other regular geometric figure laser dot matrix, the dot matrix control module is electrically connected with the skin imaging device and is used for controlling the n x m laser rectangular dot matrix or the multi-pixel circular laser dot matrix or the multi-pixel other regular geometric figure laser dot matrix to act on a part needing physical therapy according to a skin surface image transmitted by the skin imaging device; wherein n and m are selected from 7 to 200, and the laser parameters are as follows: power: no more than 20W, laser working mode: including continuous mode, super-pulse mode, intermittent mode, pulse energy: 1mJ-100mJ, energy interval 1.5-2mJ, focal spot diameter: 50 μm to 1000 μm, pulse width: 0.1ms-10 ms;

The drug delivery cavity is internally provided with a drug delivery device used for delivering drug to the LTR and/or the LTR subjected to the laser dot matrix; the dep cavity and the dosing cavity are arranged adjacent to each other in a sealing mode, and the periphery of the three-dimensional dep probe is provided with a dosing hole communicated with the dosing device, so that a medicament can permeate the skin through the dosing hole and the LTR and/or LTR under the action of laser dot matrix for physiotherapy;

the cable comprises a first power line connected with the dep device, a first signal line for controlling the working of the dep device, a second power line connected with the laser dot matrix module and the skin imaging device, a second signal line for controlling the working of the laser dot matrix module and the skin imaging device, a third power line connected with the drug delivery device and a third signal line for controlling the working of the drug delivery device, wherein the first power line, the third power line and the first signal line, the second power line and the third signal line are respectively combined into a first cable, a second cable and a third cable in a shielding mode, and the first cable, the second cable and the third cable are respectively independent into three cables;

the host comprises a display screen, three cable interfaces for connecting a first cable and a third cable, and a processor for controlling the dep device, the laser dot matrix module, the skin imaging device, the drug delivery device, parameter setting of the dep device, the laser dot matrix module, the skin imaging device, the drug delivery device and the three devices, and acquiring and analyzing physical therapy data to realize intelligent skin physical therapy; the host machine further comprises a movable support which is convenient for moving the host machine and provided with a plurality of casters.

2. The intelligent skin physiotherapy instrument of claim 1, wherein the lattice control module comprises an image acquisition module, an image processing module, and a lattice excitation module, wherein,

the image acquisition module is used for acquiring the image shot by the skin imaging device,

the image processing module is used for dividing the collected image, identifying the part which needs physical therapy and generating a control signal,

the lattice excitation module controls laser lattices in an n x m laser rectangular lattice or a multi-pixel circular laser lattice or other regular geometric figure laser lattices which are positioned at and/or near a part needing physical therapy according to the control signal to emit pulse laser to act on the part, so that the pulse laser at least partially acts on the skin stratum corneum and skin tissues below the skin stratum corneum through LTR to selectively carry out physical therapy on the skin.

3. The intelligent skin physiotherapy instrument of claim 2, wherein the image processing module comprises an image recognition unit and a control signal generation unit,

the image identification unit is used for carrying out graying according to the acquired image, dividing the grayed image into a plurality of areas to form a plurality of sub-images, identifying a total gray value g in each sub-image, if g is smaller than a preset value, taking the area where the sub-image is located as a physical therapy area, the control signal generation unit is used for generating a control signal only according to the physical therapy area in the grayed image and sending out the control signal, and the control signal generation unit is used for triggering the dot matrix excitation module to start according to the control signal of the physical therapy area where the control signal originates in the plurality of areas so as to excite the laser dot matrix where the physical therapy area is located to work to generate laser and act on the physical therapy area;

The preset value is an average value of total gray values of corresponding grayed images of the images acquired by at least one healthy skin area of the detection object, the average value is any one of an arithmetic average value and a weighted average value, and the at least one healthy skin area is determined according to the recommendation of a physical therapy doctor and/or the self-selection of a user.

4. The intelligent skin physiotherapy instrument of claim 3, wherein the image recognition unit comprises an intelligent image recognition unit, the intelligent image recognition unit establishes an artificial intelligence model according to a sub-image of the physiotherapy region of the grayed image and the control signal, the artificial intelligence model recognizes whether the control signal needs to be generated according to the sub-image, the artificial intelligence model comprises any one of a Convolutional Neural Network (CNN), a Support Vector Machine (SVM) and a generation countermeasure network (GAN), so that a corresponding control signal code, namely 1 or 0, can be recognized according to the sub-image, and thus whether the corresponding control signal needs to be generated for each sub-image is recognized.

5. The intelligent skin physiotherapy apparatus of claim 4, wherein the former scheme is adopted if the gray-scale value of the sub-image is consistent with the position of the generated control signal recognized by the artificial intelligence, and if not, one of the algorithms is set by the user in advance through the host computer to adopt the letter.

6. The intelligent skin physiotherapy instrument of any one of claims 3-5, wherein the control signal generation unit comprises a microprocessor or a single chip microcomputer, and the plurality of regions are n x m laser rectangular lattices or multi-pixel circular laser lattices or other regular geometric patterns of multiple pixels.

7. The intelligent skin physiotherapy instrument of claim 6, wherein the skin imaging device is disposed in the lattice laser area or the lattice laser cavity at the end opposite to the lattice laser area together with the n x m laser rectangular lattice or the multi-pixel circular laser lattice or the multi-pixel other regular geometric figure laser lattice, or therebetween, and is at the geometric center position of the n x m laser rectangular lattice or the multi-pixel circular laser lattice or the multi-pixel other regular geometric figure laser lattice, the skin imaging device comprising a camera and an illumination unit for illuminating the site.

8. The intelligent skin physiotherapy apparatus of claim 7, wherein said camera is a high-definition pinhole camera, and at least one of said dep region, dot matrix laser region and dosing region around said dep region is formed of a transparent material as at least a portion of said housing.

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