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CN113476584A - Hair growth agent and preparation method thereof - Google Patents

Hair growth agent and preparation method thereof Download PDF

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Publication number
CN113476584A
CN113476584A CN202110968678.9A CN202110968678A CN113476584A CN 113476584 A CN113476584 A CN 113476584A CN 202110968678 A CN202110968678 A CN 202110968678A CN 113476584 A CN113476584 A CN 113476584A
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China
Prior art keywords
parts
vitamin
ginger
arginine
radix sophorae
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CN202110968678.9A
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Chinese (zh)
Inventor
王瑞尧
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Beijing Zerun Caozuo Biotechnology Co ltd
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Beijing Zerun Caozuo Biotechnology Co ltd
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Priority to CN202110968678.9A priority Critical patent/CN113476584A/en
Publication of CN113476584A publication Critical patent/CN113476584A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415Pyridoxine, i.e. Vitamin B6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483Gleditsia (locust)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/08Antiseborrheics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a pilatory, which comprises ginger, radix sophorae flavescentis, spina gleditsiae, arginine and vitamin B6, wherein the raw materials are as follows in parts by weight: 1-2 parts of ginger, 1-3 parts of radix sophorae flavescentis, 1-2 parts of spina gleditsiae, 1-2% of arginine and 61-2% of vitamin B, and the preparation method comprises the following steps: weighing the ginger, the radix sophorae flavescentis, the spina gleditsiae, the arginine and the vitamin B6 for later use according to parts; mixing the weighed ginger, the radix sophorae flavescentis and the gleditsia sinensis lam thorn, and then soaking the mixture in 75% alcohol for 24 hours; evaporating alcohol to remove alcohol, and collecting the rest liquid; bringing the collected liquid to room temperature, and taking supernatant; adding arginine and vitamin B6 into the clear liquid, and mixing well. The invention continues the formula logic of the traditional Chinese medicine, adds the trace elements necessary for hair growth, improves the environment of hair follicles and scalp, promotes the growth of new hair, and is used for the conditions of seborrheic alopecia, alopecia areata, postpartum alopecia and the like.

Description

Hair growth agent and preparation method thereof
Technical Field
The invention relates to the field of health care, in particular to a pilatory and a preparation method thereof.
Background
Alopecia refers to the phenomenon of hair loss. The normal hair loss is the hair in the catagen and telogen phases, and the normal amount of hair can be maintained because the hair entering the catagen phase and the hair newly entering the anagen phase are constantly in dynamic balance. Pathological hair loss refers to abnormal or excessive loss of hair for a number of reasons. The hair loss process of permanent alopecia (i.e., male pattern baldness) is gradual. At the beginning, the hair edge of the forehead material is obviously retracted, and the hair at the top of the head is thin; then gradually develop, and finally develop to only leave the back part of the head and a circle of sparse hair at the two sides of the head, and the main reasons are three: 1. genetic factors, deficiency or dysregulation of male hormones in the blood circulation; 2. being too obese; 3. permanent hair loss can be caused by scars from a variety of skin diseases or skin injuries, natural hair dysplasia, and severe damage to hair follicles from chemical or physical causes. Temporary hair loss is often caused by diseases that result in high fever. However, temporary hair loss can also result from exposure to X-rays, ingestion of metals (such as thallium, tin, and arsenic) or drugs, malnutrition, certain inflammatory skin disorders, chronic wasting diseases, and endocrine disorders.
The hair growth products on the market at present have the unified defect that the hair growth products are mainly prepared from traditional Chinese medicines, but the relationship of continuing monarch, minister, assistant and world does not exist in the preparation proportion, so that the traditional Chinese medicine components added in the products are invalid or the effect is reduced sharply. In addition, the traditional Chinese medicine is used for dredging and improving but can not supplement required trace elements. Some products are actually effective in minoxidil although traditional Chinese medicine components are added, and most of additives are obtained by independently adding and mixing purchased single plant extracts.
Disclosure of Invention
The invention aims to overcome the technical defects and provides a hair restorer and a preparation method thereof.
In order to solve the problems, the technical scheme of the invention is as follows: a hair growth promoter comprises ginger, radix sophorae flavescentis, spina gleditsiae, arginine and vitamin B6, and the raw materials are as follows in parts by weight: 1-2 parts of ginger, 1-3 parts of radix sophorae flavescentis, 1-2 parts of spina gleditsiae, 1-2 parts of arginine and 61-2 parts of vitamin B.
As an improvement, the weight parts of the raw materials are as follows: 1 part of ginger, 1 part of radix sophorae flavescentis, 1 part of gleditsia sinensis thorn, 1% of arginine and 61% of vitamin B.
As an improvement, the weight parts of the raw materials are as follows: 2 parts of ginger, 3 parts of radix sophorae flavescentis, 2 parts of gleditsia sinensis thorn, 2% of arginine and 62% of vitamin B.
A method for preparing a hair restorer comprises the following steps:
(1) weighing the ginger, the radix sophorae flavescentis, the spina gleditsiae, the arginine and the vitamin B6 for later use according to parts;
(2) mixing weighed ginger, radix sophorae flavescentis and spina gleditsiae, and soaking in alcohol;
(3) evaporating alcohol to remove alcohol, and collecting the rest liquid;
(4) bringing the collected liquid to room temperature, and taking supernatant;
(5) adding arginine and vitamin B6 into the clear liquid, and mixing well.
As a modification, the alcohol concentration in the step (2) is 75%, and the soaking time is 24 hours.
The pharmacological effects are as follows:
ginger: ginger, rhizoma Zingiberis recens, with pungent flavor and slightly warm nature, enters lung, spleen and stomach meridians. Has effects in relieving exterior syndrome, dispelling cold, warming middle warmer, relieving vomit, warming lung, relieving cough, and removing toxic materials.
Flavescent sophora root: bitter taste and cold nature. They enter heart meridian, liver meridian, stomach meridian, large intestine meridian and bladder meridian. Has the effects of clearing heat, promoting diuresis, resisting bacteria, diminishing inflammation, invigorating stomach and expelling parasites when being used as a medicine.
Spina Gleditsiae: with pungent and warm natures, it enters liver and stomach meridians. Has the functions of relieving swelling, expelling pus, dispelling wind and killing parasites. Can be used for treating carbuncle, cellulitis, sore, suppuration, tinea, leprosy, etc.
Arginine: arginine can dilate blood vessels, increase blood flow, reduce vascular resistance, improve systemic blood circulation, and has the effects of providing immunity, regulating acid-base moisture and balancing oil for skin.
Vitamin B6: vitamin B6 is involved in amino acid metabolism: including transamination, decarboxylation, side chain cleavage, dehydration and transsulfuration. These biochemical functions are multifaceted. The vitamin B6 participates in human metabolism, acts on hair through blood circulation, and can prevent hair loss and reduce white hair growth.
Compared with the prior art, the invention has the advantages that: the invention continues the logic of the traditional Chinese medicine prescription on the traditional Chinese medicine components and gives play to the medicine components to the maximum extent. And a unique mixed extraction process is adopted, so that the organic chemical reaction of the first stage is generated in the soaking process by adding the Chinese medicinal materials. Completely conforms to the most basic logic of the prescription of the traditional Chinese medicine. In addition, on the basis of the traditional Chinese medicine, the traditional Chinese medicine has the effects of promoting blood circulation, resisting bacteria and diminishing inflammation, the trace elements necessary for hair growth are added, and vitamins and amino acids necessary for hair growth are provided from the root. The part can not effectively reach the required part through food intake, the metabolism loss of the whole body is too large, and the hair growth requirement of the required part can not be met, so the part needs to be supplemented by an external coating mode. The traditional Chinese medicine has the effects of activating blood, resisting bacteria and dredging, can effectively absorb trace elements and regulate sebaceous gland secretion. The invention continues the formula logic of the traditional Chinese medicine, adds the trace elements necessary for hair growth, improves the environment of hair follicles and scalp, promotes the growth of new hair, and is used for the conditions of seborrheic alopecia, alopecia areata, postpartum alopecia and the like.
Drawings
FIG. 1 is a flow chart of a method of making the present invention.
Detailed Description
The present invention is further described below by way of specific examples, but the present invention is not limited to only the following examples. Variations, combinations, or substitutions of the invention, which are within the scope of the invention or the spirit, scope of the invention, will be apparent to those of skill in the art and are within the scope of the invention.
Example one
A hair growth agent comprises the following raw materials in parts by weight: 1 part of ginger, 1 part of radix sophorae flavescentis, 1 part of gleditsia sinensis thorn, 1% of arginine and 61% of vitamin B.
The manufacturing method comprises the following steps: weighing the ginger, the radix sophorae flavescentis, the spina gleditsiae, the arginine and the vitamin B6 for later use according to parts; mixing the weighed ginger, the radix sophorae flavescentis and the gleditsia sinensis lam thorn, and then soaking the mixture in 75% alcohol for 24 hours; evaporating alcohol to remove alcohol, and collecting the rest liquid; bringing the collected liquid to room temperature, and taking supernatant; adding arginine and vitamin B6 into the clear liquid, and mixing well.
Example two
A hair growth agent comprises the following raw materials in parts by weight: 2 parts of ginger, 3 parts of radix sophorae flavescentis, 2 parts of gleditsia sinensis thorn, 2% of arginine and 62% of vitamin B.
The manufacturing method comprises the following steps: weighing the ginger, the radix sophorae flavescentis, the spina gleditsiae, the arginine and the vitamin B6 for later use according to parts; mixing the weighed ginger, the radix sophorae flavescentis and the gleditsia sinensis lam thorn, and then soaking the mixture in 75% alcohol for 24 hours; evaporating alcohol to remove alcohol, and collecting the rest liquid; bringing the collected liquid to room temperature, and taking supernatant; adding arginine and vitamin B6 into the clear liquid, and mixing well.
In the specific use, the required part is smeared for 2-3 times every day, at least once every morning and evening, and 1-2 ml of the ointment is applied every time, and the smeared part is gently kneaded after being smeared, so that the absorption of the hair growth agent is promoted.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the present invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention should be included in the scope of the present invention.

Claims (5)

1. A hair restorer characterized in that: comprises ginger, radix sophorae flavescentis, spina gleditsiae, arginine and vitamin B6, and the weight parts of the raw materials are as follows: 1-2 parts of ginger, 1-3 parts of radix sophorae flavescentis, 1-2 parts of spina gleditsiae, 1-2 parts of arginine and 61-2 parts of vitamin B.
2. A hair restorer according to claim 1, characterized in that: the weight parts of the raw materials are as follows: 1 part of ginger, 1 part of radix sophorae flavescentis, 1 part of gleditsia sinensis thorn, 1% of arginine and 61% of vitamin B.
3. A hair restorer according to claim 1, characterized in that: the weight parts of the raw materials are as follows: 2 parts of ginger, 3 parts of radix sophorae flavescentis, 2 parts of gleditsia sinensis thorn, 2% of arginine and 62% of vitamin B.
4. A method for preparing a hair restorer is characterized in that: the manufacturing method comprises the following steps:
(1) weighing the ginger, the radix sophorae flavescentis, the spina gleditsiae, the arginine and the vitamin B6 for later use according to parts;
(2) mixing weighed ginger, radix sophorae flavescentis and spina gleditsiae, and soaking in alcohol;
(3) evaporating alcohol to remove alcohol, and collecting the rest liquid;
(4) bringing the collected liquid to room temperature, and taking supernatant;
(5) adding arginine and vitamin B6 into the clear liquid, and mixing well.
5. The method for producing a hair tonic according to claim 4, characterized in that: the concentration of the alcohol in the step (2) is 75%, and the soaking time is 24 hours.
CN202110968678.9A 2021-08-23 2021-08-23 Hair growth agent and preparation method thereof Pending CN113476584A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110968678.9A CN113476584A (en) 2021-08-23 2021-08-23 Hair growth agent and preparation method thereof

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Application Number Priority Date Filing Date Title
CN202110968678.9A CN113476584A (en) 2021-08-23 2021-08-23 Hair growth agent and preparation method thereof

Publications (1)

Publication Number Publication Date
CN113476584A true CN113476584A (en) 2021-10-08

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CN202110968678.9A Pending CN113476584A (en) 2021-08-23 2021-08-23 Hair growth agent and preparation method thereof

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108815483A (en) * 2018-08-07 2018-11-16 鑫荣生物科技(广州)有限公司 Anti-dandruff and itching-relieving anticreep Chinese medicine extract and preparation method thereof
CN110693786A (en) * 2019-11-15 2020-01-17 蒙建玲 Traditional Chinese medicine hair conditioner and preparation method thereof
CN113648269A (en) * 2021-09-26 2021-11-16 大有药业扬州有限公司 Shampoo with hair loss prevention function and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108815483A (en) * 2018-08-07 2018-11-16 鑫荣生物科技(广州)有限公司 Anti-dandruff and itching-relieving anticreep Chinese medicine extract and preparation method thereof
CN110693786A (en) * 2019-11-15 2020-01-17 蒙建玲 Traditional Chinese medicine hair conditioner and preparation method thereof
CN113648269A (en) * 2021-09-26 2021-11-16 大有药业扬州有限公司 Shampoo with hair loss prevention function and preparation method thereof

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Application publication date: 20211008

RJ01 Rejection of invention patent application after publication