CN113440437A - Stain-removing and whitening toothpaste and preparation method thereof - Google Patents
Stain-removing and whitening toothpaste and preparation method thereof Download PDFInfo
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- CN113440437A CN113440437A CN202110534197.7A CN202110534197A CN113440437A CN 113440437 A CN113440437 A CN 113440437A CN 202110534197 A CN202110534197 A CN 202110534197A CN 113440437 A CN113440437 A CN 113440437A
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- calcium
- pectin
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- 239000000606 toothpaste Substances 0.000 title claims abstract description 61
- 229940034610 toothpaste Drugs 0.000 title claims abstract description 59
- 230000002087 whitening effect Effects 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 22
- 239000001814 pectin Substances 0.000 claims abstract description 67
- 235000010987 pectin Nutrition 0.000 claims abstract description 67
- 229920001277 pectin Polymers 0.000 claims abstract description 67
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims abstract description 59
- 239000011575 calcium Substances 0.000 claims abstract description 59
- 229910052791 calcium Inorganic materials 0.000 claims abstract description 59
- 239000004005 microsphere Substances 0.000 claims abstract description 35
- 239000006072 paste Substances 0.000 claims abstract description 31
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 28
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 26
- 239000003906 humectant Substances 0.000 claims abstract description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 17
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 14
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 claims abstract description 14
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 14
- 235000012239 silicon dioxide Nutrition 0.000 claims abstract description 14
- 229940075582 sorbic acid Drugs 0.000 claims abstract description 14
- 235000010199 sorbic acid Nutrition 0.000 claims abstract description 14
- 239000004334 sorbic acid Substances 0.000 claims abstract description 14
- 239000011709 vitamin E Substances 0.000 claims abstract description 14
- 229940046009 vitamin E Drugs 0.000 claims abstract description 14
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 14
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims abstract description 13
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229940057950 sodium laureth sulfate Drugs 0.000 claims abstract description 13
- SXHLENDCVBIJFO-UHFFFAOYSA-M sodium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O SXHLENDCVBIJFO-UHFFFAOYSA-M 0.000 claims abstract description 13
- 239000000811 xylitol Substances 0.000 claims abstract description 13
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims abstract description 13
- 229960002675 xylitol Drugs 0.000 claims abstract description 13
- 235000010447 xylitol Nutrition 0.000 claims abstract description 13
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000000853 adhesive Substances 0.000 claims abstract description 11
- 230000001070 adhesive effect Effects 0.000 claims abstract description 11
- 239000001525 mentha piperita l. herb oil Substances 0.000 claims abstract description 8
- 235000019477 peppermint oil Nutrition 0.000 claims abstract description 8
- 230000001804 emulsifying effect Effects 0.000 claims abstract description 7
- 239000005543 nano-size silicon particle Substances 0.000 claims abstract description 7
- 239000002994 raw material Substances 0.000 claims abstract description 7
- 238000003756 stirring Methods 0.000 claims description 28
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 18
- 238000002156 mixing Methods 0.000 claims description 15
- 239000000084 colloidal system Substances 0.000 claims description 14
- 238000001035 drying Methods 0.000 claims description 12
- 239000002245 particle Substances 0.000 claims description 12
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 11
- -1 oxydiphenylene Chemical group 0.000 claims description 9
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 6
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 6
- 239000002202 Polyethylene glycol Substances 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 229920001223 polyethylene glycol Polymers 0.000 claims description 6
- 239000000377 silicon dioxide Substances 0.000 claims description 6
- 229960001866 silicon dioxide Drugs 0.000 claims description 6
- 239000000600 sorbitol Substances 0.000 claims description 6
- 239000000230 xanthan gum Substances 0.000 claims description 6
- 229920001285 xanthan gum Polymers 0.000 claims description 6
- 235000010493 xanthan gum Nutrition 0.000 claims description 6
- 229940082509 xanthan gum Drugs 0.000 claims description 6
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims description 5
- 229910001424 calcium ion Inorganic materials 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 229920002907 Guar gum Polymers 0.000 claims description 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 2
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 2
- 239000000679 carrageenan Substances 0.000 claims description 2
- 235000010418 carrageenan Nutrition 0.000 claims description 2
- 229920001525 carrageenan Polymers 0.000 claims description 2
- 229940113118 carrageenan Drugs 0.000 claims description 2
- 239000000665 guar gum Substances 0.000 claims description 2
- 235000010417 guar gum Nutrition 0.000 claims description 2
- 229960002154 guar gum Drugs 0.000 claims description 2
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 2
- 229940071826 hydroxyethyl cellulose Drugs 0.000 claims description 2
- 238000004321 preservation Methods 0.000 claims description 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 2
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 2
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims description 2
- 208000006558 Dental Calculus Diseases 0.000 abstract description 3
- 239000003795 chemical substances by application Substances 0.000 abstract description 3
- 238000005299 abrasion Methods 0.000 abstract description 2
- 230000007547 defect Effects 0.000 abstract description 2
- 238000012545 processing Methods 0.000 abstract description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 12
- 238000000034 method Methods 0.000 description 8
- 229910000019 calcium carbonate Inorganic materials 0.000 description 6
- 238000000227 grinding Methods 0.000 description 5
- 238000004140 cleaning Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 239000003082 abrasive agent Substances 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 2
- 210000000214 mouth Anatomy 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 230000001953 sensory effect Effects 0.000 description 2
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 208000002064 Dental Plaque Diseases 0.000 description 1
- 208000025157 Oral disease Diseases 0.000 description 1
- 238000012644 addition polymerization Methods 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- JUNWLZAGQLJVLR-UHFFFAOYSA-J calcium diphosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])(=O)OP([O-])([O-])=O JUNWLZAGQLJVLR-UHFFFAOYSA-J 0.000 description 1
- 229940043256 calcium pyrophosphate Drugs 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 235000019821 dicalcium diphosphate Nutrition 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000004195 gingiva Anatomy 0.000 description 1
- 230000036449 good health Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000006651 lactation Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 208000030194 mouth disease Diseases 0.000 description 1
- 208000028169 periodontal disease Diseases 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/43—Guanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
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- Birds (AREA)
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- Chemical & Material Sciences (AREA)
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- Organic Chemistry (AREA)
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- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
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- Oil, Petroleum & Natural Gas (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Cosmetics (AREA)
Abstract
The invention provides stain-removing and whitening toothpaste and a preparation method thereof, and relates to the technical field of toothpaste processing. The stain removing and whitening toothpaste comprises the following raw materials: calcium pectin microspheres, a humectant, nano silicon dioxide, an adhesive, sodium laureth sulfate, sorbic acid, xylitol, vitamin E, peppermint oil, bis (oxyphenyl) biguanidino hexane and water; the preparation method comprises the steps of preparing the calcium pectin, preparing the calcium pectin microspheres, emulsifying the paste body, preparing the toothpaste and the like. The invention overcomes the defects of the prior art, adopts the pectin calcium microspheres to replace the traditional rubbing agent, has good elasticity, can effectively achieve the aim of taking out tartar by rubbing, simultaneously reduces the abrasion to the gum and the teeth, and improves the use feeling.
Description
Technical Field
The invention relates to the technical field of toothpaste processing, in particular to stain-removing and whitening toothpaste and a preparation method thereof.
Background
Toothpaste is a common cleaning product in daily life and has a long history. With the continuous development of science and technology, the continuous improvement and perfection of technological equipment, various types of toothpaste are developed in succession, the quality and the grade of products are continuously improved, and the existing toothpaste variety is developed into multifunctional toothpaste with complete variety, multiple functions and hundreds of brands from single clean toothpaste, so that the requirements of consumption levels of different levels are met. The toothpaste has the functions of removing the plaque and cleaning and polishing the tooth surface to make the oral cavity fresh, so that the main cleaning component in the toothpaste is an abrasive.
The existing abrasives are mostly particles of calcium carbonate, calcium hydrophosphate, calcium pyrophosphate, hydrated silicic acid and aluminum hydroxide, but the abrasives are hard in texture, and for some people with sensitive teeth, the use of the abrasives can cause sensitive addition polymerization of the teeth, the use feeling is not good, a large amount of moisture retention components are often required to be mixed for weakening the strong rubbing property of the teeth, and certain influence can still be caused after long-term use.
In order to achieve good use feeling, a large amount of plastic microspheres are used as a friction agent in toothpaste within a period of time, the plastic microspheres have friction performance and elasticity, and can effectively remove tartar when being added into the toothpaste, so that the use feeling can be greatly improved, and the toothpaste is popular.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides the stain-removing whitening toothpaste and the preparation method thereof, the pectin calcium microspheres are adopted to replace the traditional rubbing agent, the elasticity is good, the aim of taking out tartar by rubbing can be effectively achieved, meanwhile, the abrasion to gingiva and teeth is reduced, and the use feeling is improved.
In order to achieve the above purpose, the technical scheme of the invention is realized by the following technical scheme:
the stain removing and whitening toothpaste is prepared from the following raw materials in parts by weight: 18-20 parts of calcium pectin microspheres, 25-30 parts of humectant, 6-8 parts of nano silicon dioxide, 0.6-0.7 part of adhesive, 1.2-1.6 parts of sodium laureth sulfate, 1-2 parts of sorbic acid, 1-3 parts of xylitol, 0.1-0.2 part of vitamin E, 0.2-0.3 part of peppermint oil, 0.2-0.3 part of dioxyphenyl diguanidino hexane and 10-50 parts of water.
Preferably, the humectant is a mixture of glycerol, sorbitol and polyethylene glycol in a mass ratio of 10-12: 2-3: 3-4.
Preferably, the particle size of the pectin calcium microspheres is 10-30 μm.
Preferably, the adhesive is any one of xanthan gum, sodium carboxymethylcellulose, hydroxyethyl cellulose, guar gum and carrageenan.
The preparation method of the stain removing and whitening toothpaste comprises the following steps:
(1) preparing calcium pectin: selecting pectin and calcium hydroxide solution, preserving heat, mixing and stirring, and filtering while the pectin and calcium hydroxide solution is hot to obtain pectin calcium colloid for later use;
(2) preparing pectin calcium microspheres: drying the pectin calcium colloid in a drying oven at constant temperature, and micronizing the dried pectin calcium to obtain pectin calcium microspheres with particle size of 10-30 μm;
(3) emulsifying the paste: mixing humectant, adhesive, sodium laureth sulfate and water, stirring, adding nanometer silicon dioxide, xylitol, vitamin E and oleum Menthae Dementholatum, placing in a vacuum stirring tank, adjusting pressure, and stirring for 30-40min to obtain paste;
(4) preparing toothpaste: and (3) adding the pectin calcium microspheres, the oxydiphenylene diguanidinohexane and the sorbic acid in the step (2) into the paste in the step (3), continuously stirring for 15-20min to obtain a mixed paste, boosting the pressure to 10-12MPa, standing the mixed paste for 20-30min, and then releasing the pressure to obtain the toothpaste.
Preferably, the calcium ion concentration of the calcium hydroxide solution in the step (1) is 0.02mol/L, and the mass ratio of the calcium hydroxide solution to the pectin is 3-4: 1.
Preferably, the temperature for heat preservation and mixing in the step (1) is 45-50 ℃, and the mixing time is 2-3 h.
Preferably, the drying temperature of the pectin calcium colloid in the step (2) is 60-70 ℃, and the moisture content of the dried pectin calcium colloid is less than or equal to 5%.
Preferably, the pressure in the vacuum tank in the step (3) is 1000Pa to 100 Pa.
The invention provides stain-removing and whitening toothpaste and a preparation method thereof, and compared with the prior art, the stain-removing and whitening toothpaste has the advantages that:
(1) the calcium pectin microspheres are used as the abrasive in the toothpaste, the calcium pectin microspheres are insoluble in water and most solvents, the effect of cleaning the surfaces of teeth by friction can be effectively achieved after the calcium pectin microspheres are added into the toothpaste, and the calcium pectin microspheres have elasticity after being combined, so that excessive friction of the abrasive on gums and teeth is prevented while the teeth are cleaned, and the use feeling of the toothpaste is improved;
(2) the sorbic acid, the vitamin E, the peppermint oil and the dioxyphenyl diguanidino hexane are added to the toothpaste, so that the use feeling of the toothpaste can be effectively improved, and meanwhile, a good antibacterial and bacteriostatic effect is achieved.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention are clearly and completely described below in conjunction with the embodiments of the present invention, and it is obvious that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
the stain removing and whitening toothpaste is prepared from the following raw materials in parts by weight: 18 parts of calcium pectin microspheres, 25 parts of humectant, 6 parts of nano silicon dioxide, 0.6 part of xanthan gum, 1.2 parts of sodium laureth sulfate, 1 part of sorbic acid, 1 part of xylitol, 0.1 part of vitamin E, 0.2 part of peppermint oil, 0.2 part of bis (oxy) phenyl di-guanidino hexane and 10 parts of water.
Wherein the humectant is a mixture of glycerol, sorbitol and polyethylene glycol in a mass ratio of 10: 2: 3; the particle size of the pectin calcium microspheres is 10-30 μm.
The preparation method of the stain removing and whitening toothpaste comprises the following steps:
(1) preparing calcium pectin: selecting pectin and calcium hydroxide solution with calcium ion concentration of 0.02mol/L according to the mass ratio of 1: 3, preserving heat at 45 ℃, mixing and stirring for 2 hours, and filtering while hot to obtain pectin calcium colloid for later use;
(2) preparing pectin calcium microspheres: drying the pectin calcium colloid in a drying oven at a constant temperature of 60 ℃ to obtain dried pectin calcium with the water content of less than or equal to 5%, and performing superfine grinding to obtain pectin calcium microspheres with the particle size of 10-30 mu m for later use;
(3) emulsifying the paste: mixing humectant, adhesive, sodium laureth sulfate and water, stirring, adding nanometer silicon dioxide, xylitol, vitamin E and oleum Menthae Dementholatum, placing in a vacuum stirring tank, adjusting pressure to 1000PaPa, and stirring for 30min to obtain paste;
(4) preparing toothpaste: and (3) adding the pectin calcium microspheres, the oxydiphenylene diguanidinohexane and the sorbic acid in the step (2) into the paste in the step (3), continuously stirring for 15min to obtain a mixed paste, boosting the pressure to 10MPa, standing the mixed paste for 20min, and then relieving the pressure to obtain the toothpaste.
Example 2:
the stain removing and whitening toothpaste is prepared from the following raw materials in parts by weight: 20 parts of calcium pectin microspheres, 30 parts of humectant, 8 parts of nano silicon dioxide, 0.7 part of xanthan gum, 1.6 parts of sodium laureth sulfate, 2 parts of sorbic acid, 3 parts of xylitol, 0.2 part of vitamin E, 0.3 part of peppermint oil, 0.3 part of bis (oxy) phenyl di-guanidino hexane and 50 parts of water.
Wherein the humectant is a mixture of glycerol, sorbitol and polyethylene glycol in a mass ratio of 12: 3: 4; the particle size of the pectin calcium microspheres is 10-30 μm.
The preparation method of the stain removing and whitening toothpaste comprises the following steps:
(1) preparing calcium pectin: selecting pectin and calcium hydroxide solution with calcium ion concentration of 0.02mol/L according to the mass ratio of 1: 4, preserving heat at 50 ℃, mixing and stirring for 3 hours, and filtering while hot to obtain pectin calcium colloid for later use;
(2) preparing pectin calcium microspheres: drying the pectin calcium colloid in a drying oven at a constant temperature of 70 ℃ to obtain dried pectin calcium with the water content of less than or equal to 5%, and performing superfine grinding to obtain pectin calcium microspheres with the particle size of 30 mu m for later use;
(3) emulsifying the paste: mixing humectant, adhesive, sodium laureth sulfate and water, stirring, adding nanometer silicon dioxide, xylitol, vitamin E and oleum Menthae Dementholatum, adjusting pressure to 100Pa, and stirring for 40min to obtain paste;
(4) preparing toothpaste: and (3) adding the pectin calcium microspheres, the oxydiphenylene diguanidinohexane and the sorbic acid in the step (2) into the paste in the step (3), continuously stirring for 20min to obtain a mixed paste, boosting the pressure to 12MPa, standing the mixed paste for 30min, and then relieving the pressure to obtain the toothpaste.
Example 3:
the stain removing and whitening toothpaste is prepared from the following raw materials in parts by weight: 19 parts of calcium pectin microspheres, 28 parts of humectant, 7 parts of nano silicon dioxide, 0.65 part of xanthan gum, 1.4 parts of sodium laureth sulfate, 1.5 parts of sorbic acid, 2 parts of xylitol, 0.15 part of vitamin E, 0.25 part of peppermint oil, 0.25 part of bis (oxy) phenyl di-guanidino hexane and 30 parts of water.
Wherein the humectant is a mixture of glycerol, sorbitol and polyethylene glycol in a mass ratio of 11: 2.5: 3.5; the particle size of the pectin calcium microspheres is 10-30 μm.
The preparation method of the stain removing and whitening toothpaste comprises the following steps:
(1) preparing calcium pectin: selecting pectin and calcium hydroxide solution with calcium ion concentration of 0.02mol/L according to the mass ratio of 1: 3.5, preserving heat at 45 ℃, mixing and stirring for 2.5h, and filtering while hot to obtain pectin calcium colloid for later use;
(2) preparing pectin calcium microspheres: drying the pectin calcium colloid in a drying oven at a constant temperature of 65 ℃ to obtain dried pectin calcium with the water content of less than or equal to 5%, and performing superfine grinding to obtain pectin calcium microspheres with the particle size of 10-30 mu m for later use;
(3) emulsifying the paste: mixing humectant, adhesive, sodium laureth sulfate and water, stirring, adding nanometer silicon dioxide, xylitol, vitamin E and oleum Menthae Dementholatum, placing in a vacuum stirring tank, adjusting pressure to 500Pa, and stirring for 35min to obtain paste;
(4) preparing toothpaste: and (3) adding the pectin calcium microspheres, the oxydiphenylene diguanidinohexane and the sorbic acid in the step (2) into the paste in the step (3), continuously stirring for 18min to obtain a mixed paste, boosting the pressure to 11MPa, standing the mixed paste for 25min, and then relieving the pressure to obtain the toothpaste.
Comparative example:
the stain removing and whitening toothpaste is prepared from the following raw materials in parts by weight: 19 parts of calcium carbonate, 28 parts of humectant, 7 parts of nano silicon dioxide, 0.65 part of xanthan gum, 1.4 parts of sodium laureth sulfate, 1.5 parts of sorbic acid, 2 parts of xylitol, 0.15 part of vitamin E, 0.25 part of peppermint oil, 0.25 part of bis (oxy) phenyl di-guanidino hexane and 30 parts of water.
Wherein the humectant is a mixture of glycerol, sorbitol and polyethylene glycol in a mass ratio of 11: 2.5: 3.5.
The preparation method of the stain removing and whitening toothpaste comprises the following steps:
(1) grinding calcium carbonate: grinding calcium carbonate to obtain calcium carbonate powder with particle size of 10-30 μm;
(2) emulsifying the paste: mixing humectant, adhesive, sodium laureth sulfate and water, stirring, adding nanometer silicon dioxide, xylitol, vitamin E and oleum Menthae Dementholatum, placing in a vacuum stirring tank, adjusting pressure to 500Pa, and stirring for 35min to obtain paste;
(3) preparing toothpaste: adding the calcium carbonate powder, oxydiphenyldiguanidinohexane and sorbic acid into the paste obtained in the step (2), continuously stirring for 18min to obtain a mixed paste, boosting the pressure to 11MPa, standing the mixed paste for 25min, and then releasing the pressure to obtain the toothpaste.
And (3) detection:
selecting 80 healthy adults with age of 18-50 years, good health condition of the whole body, at least 8 natural anterior teeth in the mouth, no large-area fillings or crowns and other restorations, and exogenous color spots on teeth, and excluding the people who have serious oral diseases, chronic diseases or allergic history to test products, have late periodontal diseases, are women in gestation or lactation period, and are undergoing orthodontic treatment or wearing removable partial dentures;
the above population was randomly divided into 4 groups of 20 persons, and the tooth stains of each group were evaluated by using the Lobene stain index, the average value was determined, and then the use treatment was performed by using the toothpastes obtained in the above examples 1 to 3 and comparative example, respectively, and the use process was that the teeth were brushed once a day in the morning and at night for 2 minutes per time, and the tooth stain status after 10 days, 20 days and 30 days of tooth brushing was observed and recorded for each group of persons, and the results are shown in the following table 1:
TABLE 1
Sensory evaluations using each group of toothpastes were also recorded and the results are shown in the following table:
TABLE 2
| Group of | Average sensory evaluation score (Total score 10 points) |
| Example 1 | 9.47 |
| Example 2 | 9.32 |
| Example 3 | 9.26 |
| Comparative example | 8.96 |
In conclusion, the toothpaste prepared by the method can effectively remove dental plaque, and has good use feeling.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (9)
1. The stain removing and whitening toothpaste is characterized by being prepared from the following raw materials in parts by weight: 18-20 parts of calcium pectin microspheres, 25-30 parts of humectant, 6-8 parts of nano silicon dioxide, 0.6-0.7 part of adhesive, 1.2-1.6 parts of sodium laureth sulfate, 1-2 parts of sorbic acid, 1-3 parts of xylitol, 0.1-0.2 part of vitamin E, 0.2-0.3 part of peppermint oil, 0.2-0.3 part of dioxyphenyl diguanidino hexane and 10-50 parts of water.
2. The stain removing and whitening toothpaste as claimed in claim 1, wherein: the humectant is a mixture of glycerol, sorbitol and polyethylene glycol in a mass ratio of 10-12: 2-3: 3-4.
3. The stain removing and whitening toothpaste as claimed in claim 1, wherein: the particle size of the pectin calcium microspheres is 10-30 μm.
4. The stain removing and whitening toothpaste as claimed in claim 1, wherein: the adhesive is any one of xanthan gum, sodium carboxymethylcellulose, hydroxyethyl cellulose, guar gum and carrageenan.
5. A preparation method of stain-removing and whitening toothpaste is characterized by comprising the following steps: the preparation method of the stain removing and whitening toothpaste comprises the following steps:
(1) preparing calcium pectin: selecting pectin and calcium hydroxide solution, preserving heat, mixing and stirring, and filtering while the pectin and calcium hydroxide solution is hot to obtain pectin calcium colloid for later use;
(2) preparing pectin calcium microspheres: drying the pectin calcium colloid in a drying oven at constant temperature, and micronizing the dried pectin calcium to obtain pectin calcium microspheres with particle size of 10-30 μm;
(3) emulsifying the paste: mixing humectant, adhesive, sodium laureth sulfate and water, stirring, adding nanometer silicon dioxide, xylitol, vitamin E and oleum Menthae Dementholatum, placing in a vacuum stirring tank, adjusting pressure, and stirring for 30-40min to obtain paste;
(4) preparing toothpaste: and (3) adding the pectin calcium microspheres, the oxydiphenylene diguanidinohexane and the sorbic acid in the step (2) into the paste in the step (3), continuously stirring for 15-20min to obtain a mixed paste, boosting the pressure to 10-12MPa, standing the mixed paste for 20-30min, and then releasing the pressure to obtain the toothpaste.
6. The preparation method of the stain removing and whitening toothpaste as claimed in claim 5, wherein the preparation method comprises the following steps: the calcium ion concentration of the calcium hydroxide solution in the step (1) is 0.02mol/L, and the mass ratio of the calcium hydroxide solution to the pectin is 3-4: 1.
7. The preparation method of the stain removing and whitening toothpaste as claimed in claim 5, wherein the preparation method comprises the following steps: the temperature for heat preservation and mixing in the step (1) is 45-50 ℃, and the mixing time is 2-3 h.
8. The preparation method of the stain removing and whitening toothpaste as claimed in claim 5, wherein the preparation method comprises the following steps: in the step (2), the drying temperature of the pectin calcium colloid is 60-70 ℃, and the moisture content of the dried pectin calcium colloid is less than or equal to 5%.
9. The preparation method of the stain removing and whitening toothpaste as claimed in claim 5, wherein the preparation method comprises the following steps: and (4) the pressure in the vacuum tank in the step (3) is 1000Pa-100 Pa.
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| CN1111262A (en) * | 1993-12-02 | 1995-11-08 | 赫尔克里斯有限公司 | Pectin process and composition |
| US20060127557A1 (en) * | 2004-12-14 | 2006-06-15 | Tadahiko Takata | Process for producing glucomannan gel particles |
| DE102017109916A1 (en) * | 2017-05-09 | 2018-11-15 | CFF GmbH & Co. KG | Dentifrice and method of making such a dentifrice |
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| CN1111262A (en) * | 1993-12-02 | 1995-11-08 | 赫尔克里斯有限公司 | Pectin process and composition |
| US20060127557A1 (en) * | 2004-12-14 | 2006-06-15 | Tadahiko Takata | Process for producing glucomannan gel particles |
| DE102017109916A1 (en) * | 2017-05-09 | 2018-11-15 | CFF GmbH & Co. KG | Dentifrice and method of making such a dentifrice |
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