CN113425624A - Anti-dandruff oil control composition and preparation method and application thereof - Google Patents
Anti-dandruff oil control composition and preparation method and application thereof Download PDFInfo
- Publication number
- CN113425624A CN113425624A CN202110766391.8A CN202110766391A CN113425624A CN 113425624 A CN113425624 A CN 113425624A CN 202110766391 A CN202110766391 A CN 202110766391A CN 113425624 A CN113425624 A CN 113425624A
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- Prior art keywords
- dandruff
- oil
- control composition
- component
- composition according
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- 208000001840 Dandruff Diseases 0.000 title claims abstract description 64
- 239000000203 mixture Substances 0.000 title claims abstract description 40
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims abstract description 30
- BTSZTGGZJQFALU-UHFFFAOYSA-N piroctone olamine Chemical class NCCO.CC(C)(C)CC(C)CC1=CC(C)=CC(=O)N1O BTSZTGGZJQFALU-UHFFFAOYSA-N 0.000 claims abstract description 24
- SAVLIIGUQOSOEP-UHFFFAOYSA-N N-octanoylglycine Chemical compound CCCCCCCC(=O)NCC(O)=O SAVLIIGUQOSOEP-UHFFFAOYSA-N 0.000 claims abstract description 22
- WHMDKBIGKVEYHS-IYEMJOQQSA-L Zinc gluconate Chemical compound [Zn+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O WHMDKBIGKVEYHS-IYEMJOQQSA-L 0.000 claims abstract description 22
- 239000011593 sulfur Substances 0.000 claims abstract description 22
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- HEUQYIQQCNOXOG-UHFFFAOYSA-N N-undecanoylglycine Chemical compound CCCCCCCCCCC(=O)NCC(O)=O HEUQYIQQCNOXOG-UHFFFAOYSA-N 0.000 claims abstract description 7
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- BIVBRWYINDPWKA-VLQRKCJKSA-L Glycyrrhizinate dipotassium Chemical compound [K+].[K+].O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@](C)(CC[C@@]5(CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C)C)C(O)=O)C([O-])=O)[C@@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O BIVBRWYINDPWKA-VLQRKCJKSA-L 0.000 claims description 13
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- Cosmetics (AREA)
Abstract
The invention provides an anti-dandruff oil control composition and a preparation method and application thereof, belonging to the field of daily chemical articles, and comprising an anti-dandruff component and/or an oil control component, wherein the anti-dandruff component is selected from one or more of sulfur, colloidal sulfur and piroctone olamine salt, and the oil control component is selected from one or more of capryloyl glycine, undecylenoyl glycine and zinc gluconate. The anti-dandruff oil-control composition disclosed by the invention comprises an anti-dandruff component or/and an oil-control component, so that the micro-ecological environment of the scalp can be improved, sebum secretion is regulated, the anti-dandruff oil-control synergistic effect of the composition can be realized through compounding of the components, and the barrier function of the scalp can be further favorably improved.
Description
Technical Field
The invention belongs to the field of daily chemical articles, and particularly relates to an anti-dandruff oil-control composition.
Background
Dandruff is the exfoliative corneocytes of the scalp, which are normally very rarely exfoliated and not visible, but when the corneocytes are abnormally separated, a large amount of flaky dandruff is exfoliated, i.e., a large amount of fine white or gray scales are accumulated on the surface of the scalp.
The malassezia is generally present on human skin, and normally maintains a balanced state, but when the endocrine of a human body is disordered or is stimulated by the outside, the balance is broken, lipophilic malassezia degrades triglyceride in fat into free fatty acid under the action of lipase, and the released oleic acid can permeate the stratum corneum to destroy the barrier function of the skin, so that the damaged barrier can lead the malassezia to excessively reproduce, and on the contrary, the secretion of sebum can be increased, thereby causing dandruff.
Next, excessive sebum secretion is another cause of the generation of a large amount of dandruff, sebum is secreted to protect skin and hair, and when endocrine is vigorous, seborrheic dermatitis is generated, or external stimulation is applied, the sebum is secreted in a large amount, and the secreted sebum is easily oxidized or decomposed by external factors (ultraviolet rays, malassezia, and the like), so that sebum free fatty acids and triglycerides are unbalanced, lipid is excessively oxidized, and further, itching of the head, dandruff, alopecia, and the like are caused.
In order to control the generation of dandruff, a large number of anti-dandruff shampoos are available on the market at present, and the existing anti-dandruff shampoos mainly use Zinc Pyrithione (ZPT) as an effective raw material, but the ZPT is limited in dosage form, easy to discolor and poor in product stability.
Disclosure of Invention
Based on the background problems, the invention aims to provide an anti-dandruff oil-control composition which is good in stability, capable of improving the micro-ecological environment of scalp, regulating sebum secretion and mildly removing dandruff; the invention also aims to provide a preparation method and application of the anti-dandruff oil control composition.
In order to achieve the above object, on one hand, the embodiment of the present invention provides a technical solution:
an antidandruff oil control composition comprising an antidandruff component selected from one or more of sulphur, colloidal sulphur, piroctone olamine, or an oil control component selected from one or more of capryloyl glycine, undecylenoyl glycine, zinc gluconate.
Further, the anti-dandruff oil control composition comprises: sulfur, piroctone olamine, caprylylglycine, and zinc gluconate.
Furthermore, the anti-dandruff oil-control composition comprises the following raw materials in percentage by mass:
0.01-5% of sulfur, 0.01-1% of piroctone olamine salt, 0.01-2% of caprylyl glycine, 0.01-2% of zinc gluconate, 0.1-10% of humectant, 0.01-2% of antiallergic agent, 0.05-3% of preservative and the balance of solvent.
Further, the humectant is selected from one or more of betaine, panthenol, sodium PCA, glycolipid, phytosterol and hyaluronic acid.
Further, the antiallergic agent is selected from one or more of dipotassium glycyrrhizinate, allantoin and bisabolol.
Further, the preservative is selected from one or more of dichlorobenzyl alcohol, salicylic acid, phenoxyethanol, benzyl alcohol, sodium benzoate and sodium salicylate.
Further, the solvent is water or/and alcohol.
The anti-dandruff component of the invention can be sulfur, colloidal sulfur, piroctone olamine or a combination thereof, wherein the sulfur and the colloidal sulfur can kill bacteria and fungi, soften the epidermis, dissolve cutin and remove dead skin, and are effective components for preventing dandruff and seborrheic dermatitis.
The piroctone olamine salt can effectively inhibit the growth of bacteria and fungi, has a remarkable bacteriostatic effect on malassezia in particular, can eliminate free radicals and regulate sebum secretion through the antioxidant performance of the piroctone olamine salt, has high safety and can reduce scalp irritation.
The oil control component can be caprylyl glycine, undecylenoyl glycine, zinc gluconate or a combination thereof, caprylyl glycine and zinc gluconate are used as multi-effect active factors and can effectively regulate the skin ecosystem, and caprylyl glycine and undecylenoyl glycine are used as biological carriers of glycine and play an important role in metabolism of skin cells, and the caprylyl glycine and the zinc gluconate can inhibit sebum secretion by inhibiting the activity of 5-alpha reductase in scalp and hair care so as to achieve the oil control effect and have the function of inhibiting bacterial reproduction and further inhibit the generation of dandruff.
According to the anti-dandruff oil-control composition disclosed by the invention, at least one of the anti-dandruff component and the oil-control component is compounded for use, so that the micro-ecological environment of the scalp can be improved, sebum secretion is regulated, and dandruff can be removed mildly, and the anti-dandruff oil-control synergistic effect of the composition can be realized through compounding of the components, so that the barrier function of the scalp can be improved.
In another aspect, an embodiment of the present invention further provides a method for preparing an anti-dandruff oil-control composition, including the following steps:
mixing the dandruff removing component, the oil control component and a solvent, heating, and stirring until the components are completely dissolved to obtain a functional component solution;
after cooling, adding the humectant and the antiallergic agent into the functional component solution, and stirring until the humectant and the antiallergic agent are completely dissolved to obtain a pre-product;
and after the secondary cooling, adding the preservative into the pre-product, and stirring until the preservative is completely dissolved to obtain the anti-dandruff oil-control composition.
Further, the temperature is increased to 70-75 ℃, the temperature is reduced to 50-53 ℃, and the temperature is reduced to 45-47 ℃ for the second time.
When the anti-dandruff oil-control composition is prepared, the raw materials can be promoted to be dissolved by heating to 70-75 ℃, if the temperature is higher than 75 ℃, the solvent can be excessively volatilized, and the raw materials can be decomposed due to too high temperature; the humectant, the antiallergic agent and the preservative are added after the temperature is reduced, so that the decomposition of part of the raw materials due to overhigh temperature can be prevented.
In a third aspect, the embodiments of the present invention further provide an application of the above-mentioned anti-dandruff oil-control composition in a scalp and hair cleansing and caring product, which includes shampoo, hair conditioner, scalp caring cream, and scalp essence.
Compared with the prior art, the invention has the following effects:
the anti-dandruff oil-control composition disclosed by the invention comprises an anti-dandruff component or/and an oil-control component, so that the micro-ecological environment of the scalp can be improved, sebum secretion is regulated, the anti-dandruff oil-control synergistic effect of the composition can be realized through compounding of the components, and the barrier function of the scalp can be further favorably improved.
Detailed Description
In order to solve the problems of poor stability and the like of the existing anti-dandruff shampoo which mainly uses zinc pyrithione as an effective raw material, the invention provides the anti-dandruff oil-control composition which not only can improve the micro-ecological environment of scalp, adjust sebum secretion and mildly remove dandruff, but also can realize the anti-dandruff oil-control synergistic effect of the composition through the compounding of the components, and is more beneficial to improving the barrier function of scalp.
It should be noted that the colloidal sulfur used in the examples of the present invention is a conventional product, and is composed of 75% sulfur and 25% gum arabic.
The invention will be elucidated by means of specific embodiments.
Example 1
The anti-dandruff oil-control composition is composed of the following raw materials in percentage by mass:
0.01% of sulfur, 5% of colloidal sulfur, 0.01% of piroctone olamine salt, 2% of capryloyl glycine, 0.01% of zinc gluconate, 10% of hyaluronic acid, 0.01% of allantoin, 0.05% of sodium benzoate and 82.92% of water.
The preparation method of the anti-dandruff oil-control composition of the embodiment comprises the following steps:
(1) adding the weighed water, sulfur, colloidal sulfur, piroctone olamine salt, caprylyl glycine and zinc gluconate into an emulsifying pot, heating to 70 ℃, and stirring until the materials are completely dissolved to obtain a functional component solution;
(2) cooling to 50 ℃, adding hyaluronic acid and allantoin into the functional component solution, and stirring until complete dissolution to obtain a pre-product;
(3) and (3) after the temperature is reduced to 45 ℃ for the second time, adding sodium benzoate into the pre-product, stirring until the sodium benzoate is completely dissolved, and regulating and controlling the pH value to be within the range of 4-7 to obtain the anti-dandruff oil-control composition.
Example 2
The anti-dandruff oil-control composition is composed of the following raw materials in percentage by mass:
5% of sulfur, 0.01% of colloidal sulfur, 1% of piroctone olamine salt, 0.01% of undecylenoyl glycine, 2% of zinc gluconate, 0.1% of panthenol, 2% of bisabolol, 3% of sodium salicylate and 91.88% of water.
The preparation method of the anti-dandruff oil-control composition of the embodiment comprises the following steps:
(1) adding the weighed water, sulfur, colloidal sulfur, piroctone olamine salt, undecylenoyl glycine and zinc gluconate into an emulsifying pot, heating to 75 ℃, and stirring until the materials are completely dissolved to obtain a functional component solution;
(2) cooling to 53 ℃, adding panthenol and bisabolol into the functional component solution, and stirring until the panthenol and the bisabolol are completely dissolved to obtain a pre-product;
(3) and (3) after the temperature is reduced to 47 ℃ for the second time, adding sodium salicylate into the pre-product, stirring until the sodium salicylate is completely dissolved, and regulating the pH value to be within the range of 4-7 to obtain the anti-dandruff oil-control composition.
Example 3
The shampoo is composed of the following raw materials in parts by mass:
7% of cocamidopropyl betaine, 5.25% of C14-16 sodium olefin sulfonate, 2% of cocamidomethyl MEA (methyl MEA), 0.5% of sulfur, 0.1% of piroctone olamine salt, 0.5% of betaine, 0.5% of panthenol, 0.3% of sugar ester, 0.05% of dipotassium glycyrrhizinate, 0.12% of dichlorobenzyl alcohol, 0.32% of phenoxyethanol and 83.36% of water.
The preparation method of the shampoo comprises the following steps:
(1) adding cocamidopropyl betaine, C14-16 olefin sodium sulfonate, cocamidomethyl MEA, sulfur, piroctone olamine and water which are weighed according to the proportion into an emulsifying pot, heating to 75 ℃, and preserving heat and stirring until the cocamidopropyl betaine, the C14-16 olefin sodium sulfonate, the cocamidomethyl MEA, the sulfur, the piroctone olamine and the water are completely dissolved;
(2) cooling to 50 ℃, adding the betaine, the panthenol, the glycolipid and the dipotassium glycyrrhizinate which are weighed according to the proportion into the emulsifying pot in the step (1), and keeping the temperature and stirring until the components are completely dissolved;
(3) and (3) cooling to 45 ℃ for the second time, adding dichlorobenzyl alcohol and phenoxyethanol which are weighed according to the proportion into the emulsifying pot in the step (2), and keeping the temperature and stirring uniformly.
The shampoo prepared in the embodiment is stored at the temperature of 50 ℃ to-8 ℃ for two months respectively, after the test is finished, the shampoo is not discolored, the viscosity of the shampoo is still uniform, and no obvious change is generated, which shows that the stability of the shampoo added with the anti-dandruff oil-control composition is good.
Example 4
The shampoo is composed of the following raw materials in parts by mass:
7% of cocamidopropyl betaine, 5.25% of C14-16 sodium olefin sulfonate, 2% of cocamidomethyl MEA, 0.5% of sulfur, 0.3% of piroctone olamine, 0.5% of caprylyl glycine, 1% of betaine, 0.5% of panthenol, 1% of sugar ester, 0.05% of dipotassium glycyrrhizinate, 0.12% of dichlorobenzyl alcohol, 0.32% of phenoxyethanol and 81.46% of water.
The preparation method of the shampoo of the embodiment is the same as that of the embodiment 3.
Example 5
The shampoo is composed of the following raw materials in parts by mass:
7% of cocamidopropyl betaine, 5.25% of C14-16 sodium olefin sulfonate, 2% of cocamidomethyl MEA, 0.5% of sulfur, 0.3% of piroctone olamine, 0.5% of caprylyl glycine, 0.2% of zinc gluconate, 1% of betaine, 0.5% of panthenol, 1% of sugar ester, 0.05% of dipotassium glycyrrhizinate, 0.12% of dichlorobenzyl alcohol, 0.32% of phenoxyethanol and 81.26% of water.
The preparation method of the shampoo of the embodiment is the same as that of the embodiment 3.
Example 6
The shampoo is composed of the following raw materials in parts by mass:
7% of cocamidopropyl betaine, 5.25% of C14-16 sodium olefin sulfonate, 2% of cocamidomethyl MEA, 1% of sulfur, 0.5% of piroctone olamine salt, 0.5% of caprylyl glycine, 0.5% of zinc gluconate, 1% of betaine, 0.5% of panthenol, 1% of sugar ester, 0.05% of dipotassium glycyrrhizinate, 0.12% of dichlorobenzyl alcohol, 0.32% of phenoxyethanol and 80.26% of water.
The preparation method of the shampoo of the embodiment is the same as that of the embodiment 3.
Example 7
The shampoo is composed of the following raw materials in parts by mass:
7% of cocamidopropyl betaine, 5.25% of C14-16 sodium olefin sulfonate, 2% of cocamidomethyl MEA, 2% of sulfur, 0.75% of piroctone olamine salt, 1% of caprylyl glycine, 1% of zinc gluconate, 1% of betaine, 1% of panthenol, 2% of sugar ester, 0.05% of dipotassium glycyrrhizinate, 0.12% of dichlorobenzyl alcohol, 0.32% of phenoxyethanol and 76.51% of water.
The preparation method of the shampoo of the embodiment is the same as that of the embodiment 3.
Example 8
The shampoo is composed of the following raw materials in parts by mass:
7% of cocamidopropyl betaine, 5.25% of C14-16 sodium olefin sulfonate, 2% of cocamidomethyl MEA, 1% of sulfur, 0.5% of caprylyl glycine, 0.5% of zinc gluconate, 1% of betaine, 0.5% of panthenol, 1% of sugar ester, 0.05% of dipotassium glycyrrhizinate, 0.12% of dichlorobenzyl alcohol, 0.32% of phenoxyethanol and 80.76% of water.
The preparation method of the shampoo of the embodiment is the same as that of the embodiment 3.
Example 9
The shampoo is composed of the following raw materials in parts by mass:
7% of cocamidopropyl betaine, 5.25% of C14-16 sodium olefin sulfonate, 2% of cocamidomethyl MEA, 0.5% of piroctone olamine salt, 0.5% of caprylyl glycine, 0.5% of zinc gluconate, 1% of betaine, 0.5% of panthenol, 1% of sugar ester, 0.05% of dipotassium glycyrrhizinate, 0.12% of dichlorobenzyl alcohol, 0.32% of phenoxyethanol and 81.26% of water.
The preparation method of the shampoo of the embodiment is the same as that of the embodiment 3.
Example 10
The shampoo is composed of the following raw materials in parts by mass:
7% of cocamidopropyl betaine, 5.25% of C14-16 sodium olefin sulfonate, 2% of cocamidomethyl MEA, 0.5% of caprylyl glycine, 0.5% of zinc gluconate, 1% of betaine, 0.5% of panthenol, 1% of sugar ester, 0.05% of dipotassium glycyrrhizinate, 0.12% of dichlorobenzyl alcohol, 0.32% of phenoxyethanol and 81.76% of water.
The preparation method of the shampoo of the embodiment is the same as that of the embodiment 3.
Comparative example
The shampoo is composed of the following raw materials in parts by mass:
7% of cocamidopropyl betaine, 5.25% of C14-16 sodium olefin sulfonate, 2% of cocamidomethyl MEA, 0.5% of betaine, 0.5% of panthenol, 0.3% of sugar ester, 0.05% of dipotassium glycyrrhizinate, 0.12% of dichlorobenzyl alcohol, 0.32% of phenoxyethanol and 83.96% of water.
The preparation method of the shampoo of the comparative example comprises the following steps:
(1) adding the cocamidopropyl betaine, the C14-16 olefin sodium sulfonate, the cocamidomethyl MEA and the water which are weighed according to the proportion into an emulsifying pot, heating to 75 ℃, and keeping the temperature and stirring until the materials are completely dissolved;
(2) cooling to 50 ℃, adding the betaine, the panthenol, the glycolipid and the dipotassium glycyrrhizinate which are weighed according to the proportion into the emulsifying pot in the step (1), and keeping the temperature and stirring until the components are completely dissolved;
(3) and (3) cooling to 45 ℃ for the second time, adding dichlorobenzyl alcohol and phenoxyethanol which are weighed according to the proportion into the emulsifying pot in the step (2), and keeping the temperature and stirring uniformly.
In order to verify the beneficial effects of the present invention, the use effects of the shampoos prepared in examples 3-10 and comparative examples were tested, and the test method was:
selecting 90 long-hair testers (with scurf and hair oil) aged between 18 and 60 years, randomly dividing the testers into 9 groups, numbering 10 people in each group, respectively, and washing the hair with the corresponding test products every two days, wherein the using amount of the shampoo is 5-8G each time, slightly massaging the hair and the scalp during use, and evaluating the effect after using for one month.
The use effect evaluation table is shown in table 1:
table 1 evaluation table of effect
The test results are shown in table 2:
table 2 test result evaluation table
As can be seen from table 2, the shampoo added with the anti-dandruff oil-control composition of the present invention can effectively inhibit itching of the head and regulate sebum secretion, and compared with the shampoo without adding sulfur, piroctone olamine, caprylyl glycine, and zinc gluconate in the comparative example, the shampoo has obvious anti-dandruff oil-control effect and high use evaluation.
As can be seen from table 2, the shampoo of example 6 and example 7 has the highest evaluation on the use effect, which indicates that the anti-dandruff oil control effect of the four-component compound of sulfur, piroctone olamine salt, caprylyl glycine and zinc gluconate is better than the two-component or three-component compound effect.
Comparing example 3 with examples 4-10, it can be seen that the shampoo with only the anti-dandruff component was evaluated to be less effective than the shampoo with both the anti-dandruff component and the oil-control component, indicating that the combination of the anti-dandruff component and the oil-control component is more effective.
It should be noted that, for those skilled in the art, various changes and modifications can be made without departing from the inventive concept of the present invention, and these changes and modifications belong to the protection scope of the present invention.
Claims (10)
1. An antidandruff and oil control composition, characterized by comprising an antidandruff component selected from one or more of sulphur, colloidal sulphur and piroctone olamine, or an oil control component selected from one or more of capryloyl glycine, undecylenoyl glycine and zinc gluconate.
2. The anti-dandruff oil-control composition according to claim 1, comprising: sulfur, piroctone olamine, caprylylglycine, and zinc gluconate.
3. The anti-dandruff oil-control composition according to claim 2, which comprises the following raw materials in percentage by mass:
0.01-5% of sulfur, 0.01-1% of piroctone olamine salt, 0.01-2% of caprylyl glycine, 0.01-2% of zinc gluconate, 0.1-10% of humectant, 0.01-2% of antiallergic agent, 0.05-3% of preservative and the balance of solvent.
4. An antidandruff and oil control composition according to claim 3, wherein the humectant is selected from one or more of betaine, panthenol, sodium PCA, glycolipids, phytosterols, hyaluronic acid.
5. The anti-dandruff oil-control composition according to claim 3, wherein the antiallergic agent is selected from one or more of dipotassium glycyrrhizinate, allantoin and bisabolol.
6. An anti-dandruff oil-control composition according to claim 3, wherein the preservative is selected from one or more of dichlorobenzyl alcohol, salicylic acid, phenoxyethanol, benzyl alcohol, sodium benzoate, sodium salicylate.
7. The anti-dandruff oil-control composition according to claim 3, wherein the solvent is water or/and alcohol.
8. The preparation method of the anti-dandruff oil-control composition is characterized by comprising the following steps:
mixing the dandruff removing component, the oil control component and a solvent, heating, and stirring until the components are completely dissolved to obtain a functional component solution;
after cooling, adding the humectant and the antiallergic agent into the functional component solution, and stirring until the humectant and the antiallergic agent are completely dissolved to obtain a pre-product;
and after the secondary cooling, adding the preservative into the pre-product, and stirring until the preservative is completely dissolved to obtain the anti-dandruff oil-control composition.
9. The method for preparing the composition of claim 8, wherein the temperature is raised to 70-75 ℃, lowered to 50-53 ℃ and lowered to 45-47 ℃ for the second time.
10. Use of an anti-dandruff, oil-control composition according to any one of claims 1 to 7 in scalp, hair cleansing and care products including shampoos, conditioners, scalp treatment creams, and scalp essences.
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| CN114796049A (en) * | 2022-04-22 | 2022-07-29 | 吴清平 | Shampoo with anti-dandruff effect and preparation method thereof |
| CN116570521A (en) * | 2023-06-14 | 2023-08-11 | 东莞巨微新材料科技有限公司 | Scalp care composition with oil control and anti-dandruff effects and application thereof |
| WO2025093259A1 (en) * | 2023-11-01 | 2025-05-08 | Unilever Ip Holdings B.V. | Cosmetic composition |
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Application publication date: 20210924 |