CN1133478C - Low-shearing force self-sucking stirring extractor with dispersed light or heavy phase and its operation method - Google Patents
Low-shearing force self-sucking stirring extractor with dispersed light or heavy phase and its operation method Download PDFInfo
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- CN1133478C CN1133478C CNB001027492A CN00102749A CN1133478C CN 1133478 C CN1133478 C CN 1133478C CN B001027492 A CNB001027492 A CN B001027492A CN 00102749 A CN00102749 A CN 00102749A CN 1133478 C CN1133478 C CN 1133478C
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Abstract
The present invention belongs to the field of a liquid-liquid extraction device, particularly to a low-phase or heavy-phase dispersed low-shearing-force self-sucking stirring and extracting device and an operation method thereof in the process of ectracting proteins by reverse micelle. A rotating drum 4 and a rotating disk 5 are connected to a rotating shaft 3 below a self-sucking stirrer 2. The present invention can carry out intermittent and continuous operation under the condition that a two-phase interface is kept clear. The rotating drum is positioned below heavy-phase material liquid during the light-phase dispersion, and the rotating disk is positioned in the middle of the light-phase material liquid. The rotating drum is positioned above the light-phase material liquid during heavy-phase dispersion, and the rotating disk is positioned in the middle of the heavy-phase material liquid. The present invention is suitable for the extraction of an easy-emulsification system, and solves the problem of the difficulty of two-phase separation.
Description
The invention belongs to the liquid liquid extraction plant field, particularly be used for reverse micelle extraction protein process mutually light or heavy phase dispersion low-shearing force self-sucking stirring extraction device and method of operating.
Reverse micelle is the molecule aggregate that surfactant forms in organic solvent, bioactivators such as little pond energy solubilising protein wherein.By regulating conditions such as aqueous pH values, ionic strength, can optionally extract target protein.Reverse micelle method extracting protein matter operating procedure is simple, only by extraction and back extraction process, can realize the concentrated and purified of protein.Compare with traditional protein stripping technique such as salt precipitation, gel permeation chromatography, ion-exchange chromatography etc., but reverse micelle method has that treating capacity is big, selectivity good and advantage such as continued operation, be specially adapted to the extensive separation and purification of biological product.Because of it might reduce the production cost of biological product significantly, reverse micelle method extracting protein matter is subjected to extensive concern and has obtained bigger progress in recent years, has represented wide application prospect.But reverse micelle method extracting protein matter fails to realize industrialization so far, and reason is a lot, and one of them is the two-phase separation difficulty of extraction process.
The reverse micelle system contains the surfactant of higher concentration, and interfacial tension is very low, easily emulsification, phase-splitting difficulty.Especially extraction process, required ionic strength is generally lower, and this problem is more outstanding.As " bioprocess engineering " (Bioprocess Engineering, 1996,15,253-256.) point out to use spray column, packed tower, mixer-settler, rotating disc column, centrifugal extractor, membrane type extractor to carry out the process development research of reverse micelle extraction protein.Though spray column and packed tower can solve the problem of phase-splitting difficulty, mass transfer rate is too low; That is that all right is ripe in the research of membrane type extractor; The ability that mixer-settler and rotating disc column are handled easy emulsifying system is lower, and the big shearing force that produces of excessive stirring is unfavorable for the maintenance of biological substance activity, also can cause further emulsification simultaneously.The phase-splitting difficult problem not only takes place in reverse micelle extraction protein process in the extraction process, in the extraction process of hydrometallurgy, petrochemical industry, pharmaceuticals industry, oil prodution industry, food industry, biochemical industry etc., the problem of easy emulsifying system phase-splitting difficulty is also very outstanding.
Point out that as " liquid-liquid extraction process and equipment " (Atomic Energy Press, Fei Weiyang etc., 1993) mixer-settler is made up of mixing channel and defecator.At first two-phase is fully mixed under the effect of agitator in mixing channel, mixed liquor phase-splitting in defecator then.Mixer-settler is widely used in various extraction processes, and it has many advantages: two-phase fully contacts, the stage efficiency height; Disposal ability is big, and operating flexibility is good; Operational suitability is strong, can operate in than scope at very wide stream; Progression is variable; It is reliable to enlarge method for designing; Cost of equipment is lower.The major defect of mixer-settler is: floor space is big; Material and solvent hold-up amount are big; Energy consumption is generally bigger.Agitator plays a part very important in mixer-settler.Multi-form agitator is worked under different rotating speeds, and is different to the influence of the clarification phase-splitting character of the size of drop and system.At present, the alr mode of mixing channel has varied, as mechanical agitation, take out hydraulic fluid post pulse stirring, air bubbling and stir and ultrasonic agitation.Using maximum is various forms of mechanical agitation.Mechanical agitator commonly used at present mainly contains oar formula and pump formula.Dasher mainly contains horizontal oar formula, hinged joint oar formula, curved leaf oar formula and propeller type etc.; Pump formula agitator mostly is half-opened impeller or two kinds of forms of enclosed impeller, and what have connects with the imbibition short tube again.More than the agitator that in mixing channel, uses all fully be mixed into prerequisite with two-phase.And the abundant mixing of two-phase can not be avoided the problem of phase-splitting difficulty.The subject matter that mixer-settler is applied to the reverse micelle extraction process is: the two-phase separation difficulty, thus need very big defecator ability phase-splitting, this means long phase-splitting time and bigger material and solvent hold-up amount; Long phase-splitting disadvantage in time is in the maintenance of biological substance activity; Bigger material and solvent hold-up amount cause production cost higher; High-speed stirred produces the activity that bigger shearing force may be destroyed biological substance.
As " Chemical Engineering handbook " (Chemical Industry Press, second volume, 1989) point out: the self-suction gas-liquid agitator be a kind of without gas conveying machinery by agitator from when the liquid high speed rotate, producing the gas-liquid contact apparatus of negative pressure with the introduction ambient atmos, be usually used in gas liquid reaction, sweat, the froth flotation of hydrometallurgy and the aeration of sewage disposal etc. in the Chemical Manufacture.Self-absorbing type stirrer is mainly used in gas-liquid mixed, and the less liquid liquid that is used for mixes.
The objective of the invention is phase-splitting difficult problem at reverse micelle extraction protein process, provide that a kind of shearing force is low, energy consumption is low, the hold-up of material and solvent is few, floor space is little, can reduce significantly extraction process production cost, can enter heavy phase gently being dispersed into droplet mutually, or heavy phase is dispersed into drop enters light phase and provide a kind of light phase or heavy phase to disperse low-shearing force self-sucking stirring extraction device and method of operating, this device also is applicable to the extraction of other easy emulsifying system simultaneously.
Self-priming stirring extraction device of the present invention comprises motor, axle sleeve, agitator, mixing channel and baffle plate, it is characterized in that: described agitator is in mixing channel 1, and this agitator is a self-absorbing type stirrer 2, is connecting rotary drum 4 and rotating disk 5 in the bottom of its rotating shaft 3.
Rotating shaft 3 tops of described self-absorbing type stirrer 2 further include one and pass through the motor 7 that axle sleeve 6 is connected with rotating shaft 3.
Described self-absorbing type stirrer 2 disperses the bottom of light phase time rotating shaft 3 to connect rotary drum 4, and the middle part connects rotating disk 5.Wherein rotary drum 4 and rotating disk 5 lay respectively in the light feed liquid mutually 9 and heavy phase feed liquid 8 in the mixing channel 1, and rotary drum 4 is positioned at the bottom of heavy phase feed liquid 8, and rotating disk 5 is positioned at the middle part of light phase feed liquid 9.As shown in Figure 1.
The middle part of rotating shaft 3 connected rotary drum 4 when described self-absorbing type stirrer 2 disperseed heavy phase, and the bottom connects rotating disk 5.Wherein rotary drum 4 and rotating disk 5 lay respectively in the light feed liquid mutually 9 and heavy phase feed liquid 8 in the mixing channel 1, and rotary drum 4 is positioned at the top of light phase feed liquid 9, and rotating disk 5 is positioned at the middle part of heavy phase feed liquid 8, as shown in Figure 2.
The structure of the light phase time of described self-absorbing type stirrer 2 dispersions as shown in Figure 3.The epimere of rotating shaft 3 is thin circular shaft, and hypomere is the circular shaft that has cavity 14.On the circular shaft above or below the rotating disk 5, have one or more apertures 13 that communicate with the top or the top of cavity 14, diameter and number that as required can adjustment hole.Aperture 13 is arranged in light phase feed liquid 9, and the lower end of rotating shaft 3 connects the rotary drum 4 of hollow, and the cavity 14 of rotating shaft 3 communicates with the cavity 15 of rotary drum 4.Have a plurality of apertures 16 that communicate with cavity 15 on rotary drum 4, aperture 16 can be single row or multiple rows, diameter and number that as required can adjustment hole.The rotating disk 5 that is positioned at rotating shaft 3 middle parts is made up of last disk 17, following disk 18 and blade 19, or be that one or more disks are formed, wherein said blade 19 is that the center of circle is uniformly distributed in around the rotating shaft 3 and is vertically connected at up and down between the disk with rotating shaft 3, and number is more than 2.6 blade rotary drum plan structure schematic diagrames as shown in Figure 6.
Structure when described self-absorbing type stirrer 2 disperses heavy phase as shown in Figure 4.The epimere of rotating shaft 3 is thin circular shaft, and the hypomere of rotating shaft 3 is the circular shaft of hollow open, and the rotary drum 4 of hollow is positioned at the middle part of rotating shaft 3.The cavity 14 of rotating shaft 3 and the cavity 15 of rotary drum 4 are connected by the aperture in the rotating shaft 3 13.Aperture 13 can be opened top or the top that is positioned at cavity 14 in rotating shaft 3, can regulate the diameter and the number of aperture 13 as required.Have the aperture 16 that communicates with cavity 15 on the rotary drum 4, aperture 16 can be single row or multiple rows, can regulate the diameter and the number of aperture 16 as required.Rotating disk 5 is positioned at the bottom of rotating shaft 3, rotating disk 5 is made up of last disk 17, following disk 18 and blade 19, or be that one or more disks are formed, wherein said blade 19 is that the center of circle is uniformly distributed in around the rotating shaft 3 and is vertically connected at up and down between the disk with rotating shaft 3, number is more than 2.
Described rotary drum 4 is the oblate cylinder of a hollow when disperseing mutually light or heavy phase.
Mixing channel 1 can use various materials (as metal, plastics, pottery, lucite, fiberglass etc.) to process, it can be circular trough or square groove, baffled circular trough in general use when extraction progression is less, the unbaffled square groove of general use when extraction progression is more is so that connection between at different levels and minimizing occupation area of equipment.According to the volume of two-phase feed liquid and the characteristics of system, can select suitable mixing channel diameter and height.As shown in Figure 5, baffle plate 12 vertically is provided with and is uniformly distributed in the inwall of mixing channel, and width generally is the 1/12-1/8 of mixing channel diameter, and highly general identical or low a little a bit (light phase liquid level should be lower than baffle plate) with mixing channel, number generally is the 3-8 sheet.Light phase charging aperture 21 and light discharging opening 22 mutually be at light phase liquid level place, and lay respectively at different baffle plate intervals; Heavy phase charging aperture 23 and heavy phase discharging opening 24 are positioned at the lower end of mixing channel, lay respectively at different baffle plate intervals.
Light phase of the present invention or heavy phase disperse the low-shearing force self-sucking stirring extraction device when operation, and by the rotating speed of silicon controlled speed regulator control motor 7, motor 7 drives the self-absorbing type stirrer rotation.Self-absorbing type stirrer is worked under suitable rotating speed, has kept two-phase interface clear, has prevented that the self-absorbing type stirrer rotating speed is low excessively, and drop can not throw away, and can't extract; And rotating speed is too high, and drop has little time coalescence, and dispersion train thickness strengthens gradually, and two-phase can not keep clarification.
The present invention is mutually light or heavy phase dispersion low-shearing force self-sucking stirring extraction device is as follows in actual interrupted extraction operation and continuous extraction method of operating:
(1). when carrying out intermittently operated, at first in mixing channel 1, add heavy phase feed liquid 8, add light phase feed liquid 9 by light phase charging aperture 21 by heavy phase charging aperture 23.When gently disperseing mutually, rotary drum 4 is positioned at the bottom of heavy phase feed liquid 8, and rotating disk 5 is positioned at the middle part of light phase feed liquid 9; When heavy phase was disperseed, rotary drum 4 was positioned at the top of light phase feed liquid 9, and rotating disk 5 is positioned at the middle part of heavy phase feed liquid 8.Start motor 7 then and stir, keeping two-phase interface clearly under the situation, when reaching required extraction yield, stop to stir, after solution clarifies fully, successively emit heavy phase feed liquid 8 and light feed liquid 9 mutually from heavy phase discharging opening 24, operate thereby finish single extraction.
(2). when carrying out continued operation, at first in mixing channel 1, add heavy phase feed liquid 8, add light phase feed liquid 9 by light phase charging aperture 21 by heavy phase charging aperture 23.When gently disperseing mutually, rotary drum 4 is positioned at the bottom of heavy phase feed liquid 8, and rotating disk 5 is positioned at the middle part of light phase feed liquid 9; When heavy phase was disperseed, rotary drum 4 was positioned at the top of light phase feed liquid 9, and rotating disk 5 is positioned at the middle part of heavy phase feed liquid 8.Starting motor 7 then stirs, keeping two-phase interface clearly under the situation, in mixing channel 1, add heavy phase feed liquid 8 continuously by heavy phase charging aperture 23 simultaneously, in mixing channel 1, add light phase feed liquid 9 continuously by light phase charging aperture 21, and emit light phase feed liquid 9 continuously by light phase discharging opening 22 simultaneously, emit heavy phase feed liquid 8 continuously by heavy phase discharging opening 24.Described light phase feed liquid inlet amount equals light phase feed liquid load, and heavy phase feed liquid inlet amount equals heavy phase feed liquid load.The outlet feed liquid can directly be carried out back extraction or be advanced the next stage extraction.
In the light self-priming stirring extraction mixing channel that disperses mutually, the mobility status of two-phase is as follows: light phase feed liquid 9 obtains stirring under the baffling effect of the rotation of rotating disk 5 and baffle plate 12, and heavy phase feed liquid 8 obtains stirring under the baffling effect of the rotation of rotary drum 4 and baffle plate 12.Under the self-priming effect of self-absorbing type stirrer, light phase feed liquid 9 enters cavity 15 from aperture 13, the cavity 15 of flowing through, by aperture 16, be dispersed into droplet 10 and enter heavy phase feed liquid 8, light phase drop 10 contacts and realizes mass transfer at uphill process with heavy phase feed liquid 8, and light phase drop 10 arrives the interface coalescence, enters light phase feed liquid 9 then.
In the self-priming stirring extraction mixing channel that heavy phase is disperseed, the mobility status of two-phase is as follows: light phase feed liquid 9 obtains stirring under the rotation of rotary drum 4, and heavy phase feed liquid 8 obtains stirring under the rotation of rotating disk 5.Under the self-priming effect of self-absorbing type stirrer, heavy phase feed liquid 8 enters cavity 14 from rotating shaft 3 lower end apertures 20, enter the cavity 15 of rotary drum 4 by the aperture in the rotating shaft 3 13, by aperture 16, be dispersed into droplet 11 and enter light phase feed liquid 9, heavy phase drop 11 is at decline process and light 9 contacts of feed liquid mutually and realization mass transfer, and heavy phase drop 11 arrives the interface coalescences, enters heavy phase feed liquid 8 then.
The effect of axle sleeve 6 is rotor and the self-absorbing type stirrers that connect motor; The effect of motor 7 is to drive self-absorbing type stirrer to rotate, and provides and stirs and self-priming power.
When gently disperseing mutually, the effect of aperture 13 is the cavitys 14 that are communicated with space outerpace and rotating shaft 3, and imports light phase feed liquid 9 to cavity 14.The effect of cavity 14 is to carry the cavity 15 of light phase feed liquid 9 to rotary drum 4.The effect of rotary drum 4 is to stir heavy phase feed liquid 8 and throw away light phase drop 10.The effect of rotating disk 5 is to stir light phase feed liquid 9.
When heavy phase was disperseed, the effect of cavity 14 was to carry the cavity 15 of heavy phase feed liquid 8 to rotary drum 4.The effect of aperture 13 is to be communicated with the cavity 14 of rotating shaft 3 and the cavity 15 of rotary drum 4.The effect of rotary drum 4 is to stir light phase 9 and throw away heavy phase drop 11.The effect of rotating disk 5 is to stir heavy phase feed liquid 8.
The effect of mixing channel 1 is to hold heavy phase feed liquid 8 and light feed liquid 9 mutually, and the effect of baffle plate 12 is to avoid forming eddy current, makes stirring more effective.The effect of light phase charging aperture 21 is to introduce light phase feed liquid 9, and the effect of heavy phase charging aperture 23 is to introduce heavy phase feed liquid 8, and the effect of light phase discharging opening 22 is to derive light phase feed liquid 9, and the effect of heavy phase discharging opening 24 is to derive heavy phase feed liquid 8.
Two kinds of self-priming stirring extraction devices of the present invention's design efficiently solve the problem of the two-phase separation difficulty of reverse micelle extraction protein process, and are applicable to the extraction of other easy emulsifying system; This self-priming stirring extraction device investment is little, be easy to processing; Motor speed is lower during work, and power consumption is lower; Rotating disk and drum structure make self-absorbing type stirrer lower to the shearing force of solution, help the maintenance of biological substance activity such as protein.This device can be used for interrupted extraction operation and continuous extraction operation, and the scope of application is big.Especially for the continuous extraction process, can save defecator, significantly reduce the hold-up of material and solvent, reduce occupation area of equipment, thereby reduce the production cost of extraction process greatly.Low-shearing force self-sucking stirring extraction device of the present invention and method of operating are applicable to the extraction process of the easy emulsifying system of biochemical industry, hydrometallurgy, pharmaceuticals industry, petrochemical industry, oil prodution industry, food industry etc.
Below in conjunction with drawings and Examples technical scheme of the present invention is further described.
Fig. 1 the present invention gently is scattered in the self-priming stirring extraction device schematic diagram of heavy phase mutually;
Fig. 2 heavy phase of the present invention is scattered in gently mutually self-priming stirring extraction device schematic diagram;
Fig. 3 the present invention gently is scattered in heavy phase self-absorbing type stirrer schematic diagram mutually;
Fig. 4 heavy phase of the present invention is scattered in light phase self-absorbing type stirrer schematic diagram;
The vertical view of Fig. 5 mixing channel of the present invention;
Fig. 6 rotating disk plan structure of the present invention schematic diagram;
Fig. 7 embodiment of the invention 1 lysozyme extraction rate of transform and time relation schematic diagram;
Fig. 8 embodiment of the invention 2 lysozymes extraction rate of transform and time relation schematic diagram;
Fig. 9 embodiment of the invention 3 lysozymes extraction rate of transform and time relation schematic diagram;
Number in the figure is:
1. mixing channel 2. agitators 3. rotating shafts 4. rotary drums 5. rotating disks 6. axle sleeves
7. motor 8. heavy phase feed liquids 9. light phase feed liquid 10. light phase drop 11. heavy phase drops 12. baffle plates
13. 18. times disks of disk on aperture 14. cavitys 15. cavitys 16. apertures 17.
19. blade 20. apertures 21. light phase charging aperture 22. light phase discharging openings
23. heavy phase charging aperture 24. heavy phase discharging openings
-◇-330rpm -■-350rpm -●-500rpm -▲-580rpm
-mouth-0.10MKCl-zero-0.05MKCl-△-0.02MKCl
Embodiment 1:
Organic facies is 50mMAOT/ benzinum (bp.:90-120 a ℃), and water is the lysozyme of 1mg/ml, 0.05M borax-HCl buffer solution, and pH=9.00, KCl concentration is 0.1M.Mixing channel internal diameter 80mm, high 120mm, the wide 8mm of baffle plate (4).To be decentralized photo mutually gently, rotary drum 4 is positioned at the bottom of heavy phase feed liquid 8, and rotating disk 5 is positioned at the middle part (as shown in Figure 1) of light phase feed liquid 9.Rotating shaft cavity diameter 8mm, aperture 13 (4) diameter 5mm.Roller diameter 40mm, high 10mm, aperture 16 (12) diameter 3mm.Disk diameter 40mm, high 10mm.Each 200ml of water and organic facies.Carry out intermittently operated.At first in mixing channel 1, add heavy phase feed liquid 8 by heavy phase charging aperture 23, add light phase feed liquid 9 by light phase charging aperture 21, starting motor 7 then stirs, keeping two-phase interface clearly under the situation, when reaching certain extraction yield, stop to stir, wait solution to clarify fully after, successively emit heavy phase feed liquid 8 and light feed liquid 9 mutually from heavy phase discharging opening 24, thereby finish the single extraction operation.
Under suitable rotating speed, two-phase clarification, the good (see figure 7) of effect of extracting.Improving extraction rate with rotating speed increases.
Embodiment 2:
Organic facies and water are with embodiment 1, and water KCl concentration is respectively 0.1M, 0.05M, 0.02M.Agitator and mixing channel are with embodiment 1.Agitator speed is 500rpm.Each 200ml of water and organic facies.Carry out intermittently operated, operation is as embodiment 1.Under different ionic strengths, the good (see figure 8) of effect of extracting.Under lower ionic strength, two-phase keeps clarification.
Embodiment 3:
Organic facies and water are with embodiment 1.Mixing channel is decentralized photo with embodiment 1 with the heavy phase, and rotary drum 4 is positioned at the top of light phase feed liquid 9, and rotating disk 5 is positioned at the middle part of heavy phase feed liquid 8, as shown in Figure 2.Rotating shaft cavity diameter 8mm, aperture 13 (4) diameter 5mm.Roller diameter 40mm, high 5mm, aperture 16 (12) diameter 3mm.Disk diameter 40mm, high 6mm.Agitator speed 330rpm.Each 200ml of water and organic facies.Carry out intermittently operated, operation is as embodiment 1.The good (see figure 9) of effect of extracting.
Embodiment 4:
Organic facies and water are with embodiment 1.Mixing channel is with embodiment 1, and to be decentralized photo mutually gently, rotary drum 4 is positioned at the bottom of heavy phase feed liquid 8, and rotating disk 5 is positioned at the middle part (as shown in Figure 1) of light phase feed liquid 9.Rotating shaft cavity diameter 8mm, aperture 13 (4) diameter 5mm.Roller diameter 40mm, high 5mm, aperture 16 (12) diameter 3mm.Disk diameter 40mm, high 6mm.Agitator speed 500rpm.Each 200ml of water and organic facies.Carry out continued operation, in mixing channel 1, add heavy phase feed liquid 8 by heavy phase charging aperture 23, in mixing channel 1, add light phase feed liquid 9 by light phase charging aperture 21, keeping two-phase interface clearly under the situation, when reaching certain extraction yield, emit light phase feed liquid 9 continuously by light phase discharging opening 22, emit heavy phase feed liquid 8 continuously by heavy phase discharging opening 24, and additional simultaneously light phase feed liquid and heavy phase feed liquid, its light phase feed liquid inlet amount equals light phase feed liquid load, and heavy phase feed liquid inlet amount equals heavy phase feed liquid load.
Claims (6)
1. self-priming stirring extraction device, comprise motor, axle sleeve, agitator, mixing channel and baffle plate, it is characterized in that: described agitator is in mixing channel (1), this agitator is self-absorbing type stirrer (2), self-absorbing type stirrer (2) is thin circular shaft at the epimere that disperses light phase time rotating shaft (3), and hypomere is for having the circular shaft of cavity (14); On the circular shaft above or below the rotating disk (5), have one or more apertures (13) that communicate with the top or the top of cavity (14), the lower end of rotating shaft (3) connects the rotary drum (4) of hollow, and the cavity (14) of rotating shaft (3) communicates with the cavity (15) of rotary drum (4); On rotary drum (4), have the aperture (16) that communicates with cavity (15); The rotating disk (5) that is positioned at rotating shaft (3) middle part is by last disk (17), following disk (18) and blade (19) are formed, or be that one or more disks are formed, wherein said blade (19) is that the center of circle is uniformly distributed in rotating shaft (3) and be vertically connected at up and down between the disk all around with rotating shaft (3);
The epimere of described self-absorbing type stirrer (2) in mixing channel (1) rotating shaft (3) when disperseing heavy phase is thin circular shaft, and the hypomere of rotating shaft (3) is the circular shaft of hollow open, and the rotary drum of hollow (4) is positioned at the middle part of rotating shaft (3); The cavity (14) of rotating shaft (3) and the cavity (15) of rotary drum (4) are connected by the aperture (13) in the rotating shaft (3); Aperture (13) can be opened top or the top that is positioned at cavity (14) in rotating shaft (3); Have the aperture (16) that communicates with cavity 15 on the rotary drum (4); Rotating disk (5) is positioned at the bottom of rotating shaft (3), rotating disk (5) is made up of last disk (17), following disk (18) and blade (19), or be that one or more disks are formed, wherein said blade (19) is that the center of circle is uniformly distributed in rotating shaft (3) and be vertically connected at up and down between the disk all around with rotating shaft (3).
2. self-priming stirring extraction device as claimed in claim 1 is characterized in that described rotary drum (4) is the oblate cylinder of a hollow.
3. self-priming stirring extraction device as claimed in claim 1, the number that it is characterized in that described blade (19) is more than 2.
4. self-priming stirring extraction device as claimed in claim 1, the quantity that it is characterized in that having on the described rotary drum (4) aperture (16) that communicates with cavity (15) is single row or multiple rows.
5. self-priming stirring extraction device as claimed in claim 1, the top that it is characterized in that described agitator (2) further include a motor (7) that is connected with rotating shaft (3) by axle sleeve (6).
6. method of operating as any described self-priming stirring extraction device of claim 1-5 is characterized in that:
(1). when carrying out intermittently operated, in mixing channel (1), add heavy phase feed liquid (8) and light feed liquid (9) mutually; When gently disperseing mutually, the rotary drum (4) of self-absorbing type stirrer (2) is positioned at the bottom of heavy phase feed liquid (8), and rotating disk (5) is positioned at the middle part of light phase feed liquid (9); When heavy phase was disperseed, the rotary drum (4) of self-absorbing type stirrer (2) was positioned at the top of light phase feed liquid (9), and rotating disk (5) is positioned at the middle part of heavy phase feed liquid (8); Start motor (7) then and stir, keeping two-phase interface clearly under the situation, when reaching required extraction yield, stop to stir, after solution clarifies fully, successively emit heavy phase feed liquid (8) and light feed liquid (9) mutually from heavy phase discharging opening (24), operate thereby finish single extraction; Perhaps
(2). when carrying out continued operation, in mixing channel (1), add heavy phase feed liquid (8) and light feed liquid (9) mutually; When gently disperseing mutually, the rotary drum (4) of self-absorbing type stirrer (2) is positioned at the bottom of heavy phase feed liquid (8), and rotating disk (5) is positioned at the middle part of light phase feed liquid (9); When heavy phase was disperseed, the rotary drum (4) of self-absorbing type stirrer (2) was positioned at the top of light phase feed liquid (9), and rotating disk (5) is positioned at the middle part of heavy phase feed liquid (8); Starting motor (7) then stirs, keeping two-phase interface clearly under the situation, in mixing channel (1), add heavy phase feed liquid (8) continuously by heavy phase charging aperture (23) simultaneously, in mixing channel (1), add light phase feed liquid (9) continuously by light phase charging aperture (21), and emit light phase feed liquid (9) continuously by light phase discharging opening (22) simultaneously, emit heavy phase feed liquid (8) continuously by heavy phase discharging opening (24); Described light phase feed liquid inlet amount equals light phase feed liquid load, and heavy phase feed liquid inlet amount equals heavy phase feed liquid load.
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| CN100448504C (en) * | 2004-02-21 | 2009-01-07 | 西北工业大学 | Carbon Dioxide Dissolution Device |
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| CN102772913B (en) * | 2012-07-16 | 2014-12-24 | 中国科学院过程工程研究所 | Column type extraction device for pipe bundle multi-channel phase-dispersing and extraction method thereof |
| CN105312098B (en) * | 2015-11-30 | 2017-04-05 | 河南师范大学 | A kind of separatory funnel in extraction process |
| CN111481964B (en) * | 2020-03-25 | 2021-11-02 | 中国原子能科学研究院 | A miniature mixing and clarifying tank |
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|---|---|
| CN1310034A (en) | 2001-08-29 |
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