CN113289172A - Aromatic methoxyflurane inhalation device for treating emergency traumatic pain - Google Patents
Aromatic methoxyflurane inhalation device for treating emergency traumatic pain Download PDFInfo
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- CN113289172A CN113289172A CN202110598136.7A CN202110598136A CN113289172A CN 113289172 A CN113289172 A CN 113289172A CN 202110598136 A CN202110598136 A CN 202110598136A CN 113289172 A CN113289172 A CN 113289172A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
- A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
- A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0086—Inhalation chambers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0606—Face
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/10—Trunk
- A61M2210/1025—Respiratory system
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Abstract
The invention relates to the technical field of medical supplies, and provides an aromatized methoxyflurane inhalation device for treating emergency traumatic pain, which comprises a base end part, a nozzle end part and a coaxial air inhalation-exhalation chamber structure, wherein the air inhalation-exhalation chamber structure comprises an air inhalation chamber and an air exhalation chamber, and the air inhalation chamber and the air exhalation chamber are respectively communicated with the nozzle end part through an air inlet channel and an air outlet channel; the end part of the base part is communicated with the air inhalation chamber through a methoxyflurane connecting pipe and an aromatic gas connecting pipe and is communicated with the air exhalation chamber through an exhaust hole; the air breathing cavity is internally provided with an evaporation chamber, an air supply chamber and a turbulence chamber in sequence from one side of the end part of the base part to one side of the end part of the nozzle, and the air breathing cavity is internally provided with an air filtering device. The methoxyflurane and the aromatic gas are mixed for the patient to inhale the aromatized methoxyflurane, so that the tolerance of the emergency trauma patient to the analgesic is improved while effective analgesia is provided.
Description
Technical Field
The invention relates to the technical field of medical supplies, in particular to an aromatized methoxyflurane inhalation device for treating emergency traumatic pain.
Background
Storing an active agent or an inhalable liquid that is itself an active agent is often challenging, as is administration of the inhalable liquid to a patient. Due to patient preference or different circumstances of administration, the active agent (e.g., therapeutic or pharmaceutical agent) can be formulated for oral delivery in the form of tablets and capsules, for nasal delivery in the form of a spray, or for intravenous delivery as a liquid.
In order to successfully administer an active agent to the lungs of a patient for the purpose of alleviating or treating respiratory diseases, the active agent can be administered by the oral or nasal inhalation route, and it is important to select an appropriate inhalation device. These oral inhalation devices typically require delivery of the active agent to the lungs and to the desired site of action via a pressurized device.
And the use as an active agent or volatile liquid containing an active agent is known. Such as halogenated volatile liquids, which have been described as useful for inducing, maintaining anaesthesia (including amnesia, muscle paralysis, sedation) and thus as anaesthetics, analgesics. Halogenated volatile liquids, when used in general anesthesia, can be inhaled by a patient under positive pressure via a delivery system that includes a vaporizer and a breathable gas. More recently, halogenated volatile liquids have been formulated for local or regional anesthesia and analgesia via non-inhalation routes.
Inhalation devices that form liquids into respirable-sized droplets by atomization or aerosolization, or form vapors by heating, require the provision of structures including moving devices, mechanical devices, heating devices, and/or electrical devices, which add to the design, complexity of manufacture, and cost and operability for the end user.
For safe storage and handling of volatile liquids, major considerations typically include vapor pressure build-up, robustness of the container, and integrity of the container seal. Many researchers are trying to designNew inhalation device for inhalable medicaments, figure 1 shows a Green Whistle of the prior artTMInhaler device (1) (Medical Developments International Limited) which is currently used in australia to deliver methoxyflurane (1.5mL or 3mL screw-cap storage brown glass vial container) as an inhaled analgesic drug. When required for use, a delivered dose of methoxyflurane is poured into the base end (3) of the device. After methoxyflurane poured into the base end is delivered to an evaporation device (not shown), the methoxyflurane evaporates so that the patient can administer the analgesic by inhaling the air/vapor mixture through the nozzle end (2). Whilst the patient is breathing from the end of the mouthpiece, any exhaled air/vapour mixture will leave the device via an externally fitted chamber containing an activated carbon "AC chamber" (4).
However, methoxyflurane itself has a characteristic odor and is generally not tolerated by patients. Therefore, the application additionally adds an aromatic drug administration device on the basis of the existing inhalation device so as to improve the tolerance of a patient and the analgesic effect of the drug.
Disclosure of Invention
The invention aims to provide an aromatic methoxyflurane inhalation device for treating emergency traumatic pain, which aims to solve the problem of the prior art.
The embodiment of the invention is realized by the following technical scheme:
an aromatised methoxyflurane inhalation device for the treatment of emergency traumatic pain comprising a base end, a mouthpiece end and a coaxial air inhalation-exhalation chamber structure comprising an air inhalation chamber and an air exhalation chamber;
the air suction chamber, the air exhalation chamber and the end part of the nozzle form mutually independent chambers through a first clapboard, the air suction chamber and the air exhalation chamber are respectively communicated with the end part of the nozzle through an air inlet channel and an air outlet channel, an air inlet valve is arranged in the air inlet channel, and an air outlet valve is arranged in the air outlet channel;
the air inhalation chamber is positioned in the air exhalation chamber, the end part of the base part, the air inhalation chamber and the air exhalation chamber form mutually independent chambers through a second clapboard, and the second clapboard is provided with a methoxyflurane connecting pipe and an aromatic gas connecting pipe which are communicated with the air inhalation chamber, and an exhaust hole which is communicated with the air exhalation chamber;
an evaporation chamber, an air supply chamber and a turbulent flow chamber are sequentially arranged in the air suction cavity from one side of the end part of the base part to one side of the end part of the pipe nozzle, the evaporation chamber is over against the methoxyflurane connecting pipe, an evaporation supporting material for evaporating methoxyflurane liquid is arranged in the evaporation chamber, a compression fan for sending methoxyflurane and aromatic gas into the turbulent flow chamber is arranged in the air supply chamber, and a turbulent flow impeller for mixing methoxyflurane and aromatic gas is arranged in the turbulent flow chamber;
an air filtering device is arranged in the air exhalation chamber and is used for filtering the exhaled air when the patient exhales through the end part of the nozzle and enabling the exhaled air to leave through the exhaust hole.
Furthermore, the air inlet valve comprises a first valve plate connected to the inner wall of the air inlet channel in a rotating mode and a first baffle arranged on the inner wall of the air inlet channel and used for preventing the first valve plate from rotating towards one side of the air suction chamber.
Further, discharge valve sets up in the second valve plate of air outlet channel inner wall and sets up in air outlet channel inner wall and be used for the prevention the second valve plate is toward nozzle tip one side pivoted second baffle, second valve plate articulates on the side of air exhalation cavity towards has the connecting rod, be connected with the floater on the connecting rod.
Further, the internal diameter of air outlet channel is by discharge valve toward the diameter that air exhalation cavity one end grow gradually to being greater than the floater, and the air outlet channel inner chamber that is close to discharge valve department with the floater is laminated mutually.
Further, the vortex impeller is including rotating the pivot that sets up in air suction cavity inner wall and along a plurality of diaphragms of the external diameter circumference setting of pivot, the pivot both ends be provided with all diaphragm tip fixed connection's end plate.
Further, a breathing mask is arranged on the end part of the nozzle.
Further, the air filtration device includes a plurality of activated carbon particles and a gas permeable web confining the activated carbon particles within an air exhalation chamber.
The technical scheme of the embodiment of the invention at least has the following advantages and beneficial effects:
the methoxyflurane connecting pipe and the aromatic gas connecting pipe which are connected with the air suction chamber are arranged at the end part of the base part, and are used for sending methoxyflurane and aromatic gas into the air suction chamber and mixing the methoxyflurane and the aromatic gas in the air suction chamber to enable a patient to suck aromatized methoxyflurane, so that the tolerance of an emergency trauma patient to analgesic drugs is improved while effective analgesia is provided.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
FIG. 1 is a schematic view of an inhalation device according to the prior art;
FIG. 2 is a schematic diagram of the structure of an aromatase methoxyflurane inhalation device for the treatment of acute traumatic pain as provided in example 1 of the present invention;
FIG. 3 is a cross-sectional view taken along A-A of FIG. 2;
FIG. 4 is an enlarged view at B in FIG. 3;
FIG. 5 is a diagram of the status of an aromatherapy methoxyflurane inhalation device for the treatment of acute traumatic pain as provided in example 1 of the present invention upon inhalation;
FIG. 6 is a diagram of the state of an aromatherapy methoxyflurane inhalation device for the treatment of acute traumatic pain according to example 1 of the present invention during exhalation;
fig. 7 is a sectional view of a turbulator impeller.
Icon: 1-inhalation device, 2-nozzle end, 3-base end, 4-AC chamber, 5-air inhalation-exhalation chamber structure, 501-air inhalation chamber, 502-air exhalation chamber, 6-first partition, 7-air inlet channel, 8-air outlet channel, 9-air inlet valve, 901-first valve plate, 902-first baffle, 10-exhaust valve, 101-second valve plate, 102-second baffle, 103-connecting rod, 104-floating ball, 11-second partition, 12-methoxyflurane connecting pipe, 13-aromatic gas connecting pipe, 14-exhaust hole, 15-evaporation chamber, 16-evaporation support material, 17-blast chamber, 18-compression fan, 19-turbulent flow chamber, 20-turbulent flow impeller, 201-rotating shaft, 202-transverse plate, 203-end plate, 21-breathing mask, 22-activated carbon particles and 23-breathable net film.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
Referring to fig. 2 to 7, the present embodiment provides an aromatised methoxyflurane inhalation device for the treatment of emergency traumatic pain, comprising a base end 3, a nozzle end 2 and a coaxial air inhalation-exhalation chamber structure 5, said coaxial air inhalation-exhalation chamber structure 5 comprising an air inhalation chamber 501 and an air exhalation chamber 502, and said air inhalation chamber 501 being located inside the air exhalation chamber 502.
Specifically, the method comprises the following steps:
the base end part 3 and the air inhalation chamber 501 and the air exhalation chamber 502 form mutually independent chambers through the second partition plate 11, the second partition plate 11 is provided with a methoxyflurane connecting pipe 12 and an aromatic gas connecting pipe 13 which are communicated with the air inhalation chamber 501, the methoxyflurane connecting pipe 12 and the aromatic gas connecting pipe 13 are both provided with external threads so as to be connected with a container for storing methoxyflurane and aromatic gas, the second partition plate 11 is further provided with an exhaust hole 14, and the base end part 3 and the air exhalation chamber 502 are communicated through the exhaust hole 14.
The utility model discloses an air intake device, including air intake cavity 501, by 3 one side of basal portion tip to nozzle tip 2 one side in the air have set gradually evaporating chamber 15, blast chamber 17 and vortex chamber 19, evaporating chamber 15 is just to methoxyflurane connecting pipe 12, and evaporating chamber 15 is provided with the opening that supplies the circulation of methoxyflurane, be provided with evaporation support material 16 in the evaporating chamber 15, evaporation support material 16 is prior art, can refer to the suction device 1 that provides in the background art, makes methoxyflurane liquid evaporate into gaseous entering blast chamber 17 through evaporation support material 16, be provided with compressor fan 18 in the blast chamber 17, compressor fan 18 is used for sending methoxyflurane vapour and aromatic gas into vortex chamber 19, be provided with vortex impeller 20 in the vortex chamber 19, vortex impeller 20 is including rotating the pivot 201 that sets up in air intake cavity 501 inner wall and a plurality of diaphragms 202 that set up along the external diameter surface circumference of pivot 201, the both ends of pivot 201 are provided with the end plate 203 with all diaphragm 202 tip fixed connection, and after methoxy flurane vapour and fragrant gas were sent into the vortex chamber 19 by compressor fan 18, methoxy flurane vapour and fragrant gas are with certain speed striking diaphragm 202, and diaphragm 202 atress drives pivot 201 and rotates together to play the effect of mixed vortex to methoxy flurane vapour and fragrant gas, make methoxy flurane vapour full of aromatic smell, vortex chamber 19 can set up a plurality ofly, so that methoxy flurane vapour and fragrant gas intensive mixing.
The air inhalation chamber 501, the air exhalation chamber 502 and the nozzle end 2 form mutually independent chambers through the first partition plate 6, the air inhalation chamber 501 and the air exhalation chamber 502 are respectively communicated with the nozzle end 2 through the air inlet channel 7 and the air outlet channel 8, the nozzle end 2 is provided with the breathing mask 21, the breathing mask 21 is used for preventing methoxyflurane from leaking, and people around a patient are prevented from passively inhaling methoxyflurane. An air inlet valve 9 is arranged in the air inlet channel 7, an exhaust valve 10 is arranged in the air outlet channel 8, the air inlet valve 9 comprises a first valve plate 901 which is rotatably connected to the inner wall of the air inlet channel 7 and a first baffle 902 which is arranged on the inner wall of the air inlet channel 7 and used for preventing the first valve plate 901 from rotating towards one side of the air suction chamber 501, when a patient inhales air, the first valve plate 901 rotates towards one side of the end part of the nozzle to open the air inlet channel 7, and methoxyflurane steam and aromatic gas enter the end part 2 of the nozzle from the air suction chamber 501 through the air inlet channel 7 for the patient to inhale; the exhaust valve 10 comprises a second valve plate 101 rotatably arranged on the inner wall of the exhaust passage 8 and a second baffle plate 102 arranged on the inner wall of the exhaust passage 8 and used for preventing the second valve plate 101 from rotating towards one side of the end part 2 of the nozzle, the side of the second valve plate 101 facing the air exhaling chamber 502 is hinged with a connecting rod 103, the connecting rod 103 is connected with a floating ball 104, the inner diameter of the air exhaling passage 8 is gradually increased from the exhaust valve 10 to one end of the air exhaling chamber 502 to be larger than the diameter of the floating ball 104, and the inner cavity of the air exhaling passage 8 close to the exhaust valve 10 is attached to the floating ball 104, when a patient exhales, the first valve plate 901 is blocked by the first baffle plate 902 and cannot rotate towards one side of the air inhaling chamber 501, so that the air intake passage 7 is closed, the exhaled air exerts pressure on the second valve plate 101, so that the second valve plate 101 rotates towards one side of the air exhaling chamber 502, and the second valve plate 101 pushes the floating ball 104 to move towards the air exhaling chamber 502 through the connecting rod, thereby open outlet channel 8, make gaseous entering air exhalation cavity 502, be provided with air filter in the air exhalation cavity 502, air filter includes a plurality of activated carbon particle 22 and will activated carbon particle 22 limits ventilative nethike embrane 23 in the air exhalation cavity 502, and the air of exhalation is discharged from exhaust hole 14 after activated carbon particle 22 filters, exhales after accomplishing, when breathing in next time, floater 104 is at the suction effect, toward 2 one sides of nozzle tip come-up to close the exhaust passage through second valve plate 101.
As can be seen from the above, the method of using the aromatic methoxyflurane inhalation device 1 for treating emergency traumatic pain provided in this embodiment is as follows:
firstly, a container containing methoxyflurane and aromatic gas is respectively connected with a methoxyflurane connecting pipe 12 and an aromatic gas connecting pipe 13, methoxyflurane liquid is sent into an evaporation chamber 15 to be evaporated into methoxyflurane vapor, then the methoxyflurane vapor and the aromatic gas are sent into a turbulent flow chamber 19 by a compression fan 18, the methoxyflurane vapor and the aromatic gas are mixed by a turbulent flow impeller 20 and then are inhaled by a patient from an air inlet channel 7, and the exhaled gas of the patient enters an air exhalation chamber 502 through an air outlet channel 8 and is exhausted through an exhaust hole 14.
It is noted that methoxyflurane may be replaced by other halogenated volatile liquids that may be used as anesthetic analgesics, such as halothane, sevoflurane, desflurane, enflurane, isoflurane, and the like.
The above is only a preferred embodiment of the present invention, and is not intended to limit the present invention, and various modifications and changes will occur to those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (7)
1. An aromatized methoxyflurane inhalation device for the treatment of emergency traumatic pain comprising a base end, a mouthpiece end and a coaxial air inhalation-exhalation chamber structure comprising an air inhalation chamber and an air exhalation chamber, characterized in that:
the air suction chamber, the air exhalation chamber and the end part of the nozzle form mutually independent chambers through a first clapboard, the air suction chamber and the air exhalation chamber are respectively communicated with the end part of the nozzle through an air inlet channel and an air outlet channel, an air inlet valve is arranged in the air inlet channel, and an air outlet valve is arranged in the air outlet channel;
the air inhalation chamber is positioned in the air exhalation chamber, the end part of the base part, the air inhalation chamber and the air exhalation chamber form mutually independent chambers through a second clapboard, and the second clapboard is provided with a methoxyflurane connecting pipe and an aromatic gas connecting pipe which are communicated with the air inhalation chamber, and an exhaust hole which is communicated with the air exhalation chamber;
an evaporation chamber, an air supply chamber and a turbulent flow chamber are sequentially arranged in the air suction cavity from one side of the end part of the base part to one side of the end part of the pipe nozzle, the evaporation chamber is over against the methoxyflurane connecting pipe, an evaporation supporting material for evaporating methoxyflurane liquid is arranged in the evaporation chamber, a compression fan for sending methoxyflurane and aromatic gas into the turbulent flow chamber is arranged in the air supply chamber, and a turbulent flow impeller for mixing methoxyflurane and aromatic gas is arranged in the turbulent flow chamber;
an air filtering device is arranged in the air exhalation chamber and is used for filtering the exhaled air when the patient exhales through the end part of the nozzle and enabling the exhaled air to leave through the exhaust hole.
2. The aromatic methoxyflurane inhalation device for use in the treatment of emergency traumatic pain according to claim 1, characterized in that: the air inlet valve comprises a first valve plate and a first baffle, wherein the first valve plate is rotatably connected to the inner wall of the air inlet channel, and the first baffle is arranged on the inner wall of the air inlet channel and used for preventing the first valve plate from rotating towards one side of the air suction chamber.
3. The aromatic methoxyflurane inhalation device for use in the treatment of emergency traumatic pain according to claim 1, characterized in that: discharge valve sets up in the second valve plate of air outlet channel inner wall and sets up in air outlet channel inner wall and be used for preventing the second valve plate is toward nozzle tip one side pivoted second baffle, the second valve plate articulates on the side of air exhalation cavity towards has the connecting rod, be connected with the floater on the connecting rod.
4. The aromatic methoxyflurane inhalation device for use in the treatment of emergency traumatic pain according to claim 3, characterized in that: the internal diameter of air outlet channel is by discharge valve toward the diameter that air exhalation cavity one end grow gradually to being greater than the floater, and be close to air outlet channel inner chamber near discharge valve department with the floater is laminated mutually.
5. The aromatic methoxyflurane inhalation device for use in the treatment of emergency traumatic pain according to claim 1, characterized in that: the vortex impeller sets up in the pivot of air suction cavity inner wall and a plurality of diaphragms that set up along the external diameter circumference of pivot including rotating, and the pivot both ends are provided with the end plate with all diaphragm tip fixed connection.
6. The aromatic methoxyflurane inhalation device for use in the treatment of emergency traumatic pain according to claim 1, characterized in that: a breathing mask is arranged at the end part of the nozzle.
7. The aromatic methoxyflurane inhalation device for use in the treatment of emergency traumatic pain according to claim 1, characterized in that: the air filtration device includes a plurality of activated carbon particles and a gas permeable web confining the activated carbon particles within an air exhalation chamber.
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