CN113244363B

CN113244363B - An orthopedic traditional Chinese medicine herbal cake moxibustion and its preparation method and application

Info

Publication number: CN113244363B
Application number: CN202110601386.1A
Authority: CN
Inventors: 谌祖江; 王宁; 钟伟兴; 李俊桦; 邝珊珊; 冯梓誉; 廖立青; 李义凯
Original assignee: Southern Medical University
Current assignee: Southern Medical University
Priority date: 2021-05-31
Filing date: 2021-05-31
Publication date: 2022-01-04
Anticipated expiration: 2041-05-31
Also published as: CN113244363A

Abstract

The invention discloses a traditional Chinese medicine cake moxibustion for orthopedics department, a preparation method and application thereof, wherein the traditional Chinese medicine cake moxibustion comprises the following traditional Chinese medicine components: sappan wood, angelica, safflower, semen brassicae, rhizoma corydalis, cinnamon, monkshood, rhizoma zingiberis and ginger. The traditional Chinese medicine moxibustion is combined with the moxibustion, the moxibustion has the effects of promoting qi and blood circulation, warming and dredging channels and collaterals, eliminating dampness and dispelling cold, the heat of fire in the moxibustion stimulates the human body with warmth and heat, and the warmth acts on the deep layer of soft tissues, so that the effects of directly reducing the tension of local tissues, promoting blood circulation, increasing local blood supply and the like can be achieved, the chronic lumbar muscle strain and the wind-cold-dampness arthralgia can be prevented and treated, and no side effect exists.

Description

Traditional Chinese medicine cake moxibustion for orthopedics department as well as preparation method and application thereof

Technical Field

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine cake moxibustion for orthopedics department, and a preparation method and application thereof.

Background

Chronic lumbar muscle strain (Chronic lumbar muscle strain) is a clinical frequently-occurring disease and a common disease, and is one of the main pathogenic factors of Chronic low back pain. Chronic lumbar muscle strain belongs to the category of nonspecific lower back pain, and the nonspecific lower back pain accounts for more than 85% of lower back pain. In recent years, the prevalence rate of lumbago in the lower reaches 13.6%, and there is a gradually increasing tendency. The arthralgia syndrome due to wind-cold-dampness is a common and frequently encountered disease in clinic, is related to bone and joint diseases in modern medicine, is commonly seen in rheumatic Osteoarthritis (OA), Rheumatoid Arthritis (RA), Ankylosing Spondylitis (AS) and the like, and belongs to the category of arthralgia syndrome in traditional Chinese medicine. When the disease occurs, the disease causes osteoarticular pain, soreness, movement disorder and even deformity, and the health and the life quality of people are seriously influenced. The treatment of the two diseases mostly adopts non-steroidal anti-inflammatory drugs as main drugs, but the non-steroidal anti-inflammatory drugs cannot last for a long time and have certain side effects.

Disclosure of Invention

The invention aims to provide a medicinal cake moxibustion which combines traditional Chinese medicines and moxibustion to achieve the effects of preventing and treating chronic lumbar muscle strain and wind-cold-dampness arthralgia without side effects.

The technical scheme adopted by the invention is as follows:

the invention provides a traditional Chinese medicine composition, which comprises the following components: sappan wood, angelica, safflower, semen brassicae, rhizoma corydalis, cinnamon, monkshood, rhizoma zingiberis and ginger.

In some embodiments of the present invention, the traditional Chinese medicine composition comprises the following raw material medicines in parts by weight: 5-18 parts of sappan wood, 5-10 parts of Chinese angelica, 5-10 parts of safflower, 1-5 parts of semen brassicae, 5-15 parts of rhizoma corydalis, 10-12 parts of cinnamon, 5-10 parts of rhizoma typhonii, 12-20 parts of rhizoma zingiberis and 30-70 parts of ginger.

In some preferred embodiments of the present invention, the traditional Chinese medicine composition comprises the following raw material medicines in parts by weight: 15 parts of sappan wood, 10 parts of Chinese angelica, 10 parts of safflower, 3 parts of white mustard seed, 5 parts of corydalis tuber, 10 parts of cinnamon, 5 parts of monkshood, 12 parts of dried ginger and 50 parts of ginger.

The invention also provides a traditional Chinese medicine preparation which is characterized by being prepared into powder, tablets, injections, capsules, decoction, granules, pills, paste, cakes or targeted preparations by the traditional Chinese medicine composition.

The invention also provides a medicine cake moxibustion which comprises the traditional Chinese medicine composition.

In some embodiments of the invention, the cake moxibustion further comprises oil and flour.

In some embodiments of the invention, the oil is sesame oil, olive oil, sesame oil or cottonseed oil.

In some preferred embodiments of the invention, the oil is sesame oil.

In some embodiments of the present invention, the cake moxibustion comprises the following raw materials in parts by weight: 5-18 parts of sappan wood, 5-10 parts of Chinese angelica, 5-10 parts of safflower, 1-5 parts of semen brassicae, 5-15 parts of rhizoma corydalis, 10-12 parts of cinnamon, 5-10 parts of rhizoma typhonii, 12-20 parts of rhizoma zingiberis, 30-70 parts of ginger, 5-10 parts of sesame oil and 500-1500 parts of flour.

In some preferred embodiments of the present invention, the cake moxibustion comprises the following raw materials in parts by weight: 15 parts of sappan wood, 10 parts of Chinese angelica, 10 parts of safflower, 3 parts of white mustard seed, 5 parts of corydalis tuber, 10 parts of cinnamon, 5 parts of monkshood, 12 parts of dried ginger, 50 parts of ginger, 5 parts of sesame oil and 1000 parts of flour.

The invention also provides a preparation method of the medicinal cake moxibustion, which comprises the following steps:

s1: pulverizing lignum sappan, radix Angelicae sinensis, Carthami flos, semen Sinapis Albae, rhizoma corydalis, cortex Cinnamomi, radix Aconiti lateralis, and Zingiberis rhizoma, and sieving;

s2: adding water into rhizoma Zingiberis recens to obtain succus Zingiberis recens;

s3: mixing flour and the pulverized medicinal materials obtained in step S1, adding ginger juice and oil, and making into medicinal cake.

In some embodiments of the present invention, the mesh number of the screen in the step S1 is 150 to 250 mesh.

In some preferred embodiments of the present invention, the mesh number of the sieve in step S1 is 200 mesh.

In some embodiments of the present invention, the mass ratio of ginger to water in step S2 is 1: (8-12).

In some preferred embodiments of the present invention, the mass ratio of the ginger to the water in the step S2 is 1: 10.

the invention also provides application of the composition in preparing a medicament for treating chronic lumbar muscle strain and wind-cold-dampness arthralgia.

In some embodiments of the invention, the application comprises the steps of:

(1) placing the medicinal cake on the treatment acupoint, igniting folium Artemisiae Argyi, and fixing in the middle of the medicinal cake;

(2) removing the moxa stick and the medicinal cake after the moxa stick is burnt out.

In some embodiments of the present invention, the properties of the ingredients of the Chinese medicinal composition are shown in Table 1.

TABLE 1 Chinese medicine ingredients

The invention has the beneficial effects that:

the invention provides a traditional Chinese medicine composition which can effectively treat chronic lumbar muscle strain and wind-cold-dampness arthralgia, and also provides a medicine cake moxibustion, wherein the traditional Chinese medicine is combined with moxibustion, the moxibustion has the effects of promoting qi and blood circulation, warming and dredging channels and collaterals, dispelling dampness and expelling cold, and the like, the heat of fire in the moxibustion stimulates the human body with warmth and heat, and the warmth acts on the deep layer of soft tissues to directly reduce the tension of local tissues, promote blood circulation, increase the blood supply of the local parts and the like, and the traditional Chinese medicine composition is combined with the moxibustion, can prevent and treat chronic lumbar muscle strain and wind-cold-dampness arthralgia without side effects. In the formula, the dried ginger is hot and pungent, can assist yang to dispel cold, and the corydalis tuber is used for treating pain caused by qi stagnation and blood stasis of all parts of the body, and the dried ginger and the corydalis tuber are combined to be monarch drugs, so that the rheumatism and arthralgia can be eliminated, and the channels and collaterals can be warmed and dredged; the ministerial drugs comprise ginger, monkshood and cinnamon for dispelling cold, tonifying fire and supporting yang, and strengthening the effect of warmth, and the safflower and the sappan wood for promoting blood circulation, removing blood stasis and relieving pain; semen Sinapis Albae can dissipate stagnation and relieve swelling; when used together with warm nature, Dang Gui can tonify blood and activate blood.

Detailed Description

The concept and technical effects of the present invention will be clearly and completely described below in conjunction with the embodiments to fully understand the objects, features and effects of the present invention. It is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and those skilled in the art can obtain other embodiments without inventive effort based on the embodiments of the present invention, and all embodiments are within the protection scope of the present invention.

Example 1

A medicinal cake moxibustion for treating chronic lumbar muscle strain and arthralgia due to wind-cold-dampness is composed of 15 parts by mass of sappan wood, 10 parts by mass of Chinese angelica, 10 parts by mass of safflower, 5 parts by mass of white mustard seed, 5 parts by mass of corydalis tuber, 10 parts by mass of cinnamon, 5 parts by mass of monkshood, 12 parts by mass of dried ginger, 50 parts by mass of ginger, 5 parts by mass of sesame oil and 1000 parts by mass of flour. The specific components are shown in Table 2.

TABLE 2 composition of the moxibustion ingredients of the cake

A preparation method of a medicinal cake moxibustion for treating chronic lumbar muscle strain and wind-cold-dampness arthralgia comprises the following steps:

1) pulverizing lignum sappan, radix Angelicae sinensis, Carthami flos, semen Sinapis Albae, rhizoma corydalis, cortex Cinnamomi, radix Aconiti lateralis, and Zingiberis rhizoma into fine powder, sieving with 200 mesh sieve, and placing rhizoma Zingiberis recens and water in a juicer to obtain ginger juice;

2) mixing flour and the fine powder, adding succus Zingiberis recens and oleum Sesami a little for multiple times, and kneading into smooth dough, wherein the process lasts for 10 min;

3) dividing the kneaded dough into a plurality of round balls with the mass of about 3g, and wrapping the round balls by preservative films.

Example 2

Weighing the following traditional Chinese medicine raw materials in proportion:

5 parts by mass of sappan wood, 5 parts by mass of Chinese angelica, 5 parts by mass of safflower, 3 parts by mass of white mustard seed, 15 parts by mass of corydalis tuber, 10 parts by mass of cinnamon, 10 parts by mass of monkshood, 20 parts by mass of dried ginger, 70 parts by mass of ginger, 10 parts by mass of sesame oil and 1500 parts by mass of flour.

1) pulverizing lignum sappan, radix Angelicae sinensis, Carthami flos, semen Sinapis Albae, rhizoma corydalis, cortex Cinnamomi, radix Aconiti lateralis, and Zingiberis rhizoma into fine powder, sieving with 150 mesh sieve, and placing rhizoma Zingiberis recens and water in a juicer to obtain ginger juice;

2) mixing flour and the fine powder, adding succus Zingiberis recens and oleum Sesami a little for several times, and kneading into smooth dough, wherein the process lasts for 15 min;

Example 3

18 parts by mass of sappan wood, 10 parts by mass of Chinese angelica, 5 parts by mass of safflower, 1 part by mass of white mustard seed, 10 parts by mass of corydalis tuber, 10 parts by mass of cinnamon, 10 parts by mass of monkshood, 12 parts by mass of dried ginger, 30 parts by mass of ginger, 5 parts by mass of sesame oil and 500 parts by mass of flour. The preparation method is the same as example 1.

Example 4

5 parts by mass of sappan wood, 5 parts by mass of Chinese angelica, 10 parts by mass of safflower, 1 part by mass of white mustard seed, 15 parts by mass of corydalis tuber, 10 parts by mass of cinnamon, 5 parts by mass of monkshood, 20 parts by mass of dried ginger, 70 parts by mass of ginger, 8 parts by mass of sesame oil and 1000 parts by mass of flour. The preparation method is the same as example 1.

Example 5

5 parts by mass of sappan wood, 10 parts by mass of Chinese angelica, 5 parts by mass of safflower, 5 parts by mass of white mustard seed, 10 parts by mass of corydalis tuber, 10 parts by mass of cinnamon, 10 parts by mass of monkshood, 18 parts by mass of dried ginger, 30 parts by mass of ginger, 5 parts by mass of sesame oil and 1000 parts by mass of flour. The preparation method is the same as example 1.

Comparative example 1

The preparation process of this example 1 is the same as that of example 1 except that 3 parts by mass of acanthopanax bark, 5 parts by mass of asarum herb and 10 parts by mass of astragalus root are added to the traditional Chinese medicine.

Test examples

1. Patient data

302 patients with chronic lumbar muscle strain and wind-cold-dampness arthralgia who come to hospital for diagnosis in 5 months and 1 day in 2020 and 6 months and 30 days in 2020 are selected, wherein 100 male patients, 202 female patients and the average age is 30-59 years. The longest course of disease is 3 years, and the shortest is 7 days. The patients were divided into A, B groups, 151 patients in group A and 151 patients in group B, and there was no significant difference in sex, age, and course of disease between the two groups.

2. Method of treatment

Group a patients: the cake prepared in example 1 was subjected to moxibustion for topical application 3 times a week for 15 minutes, with 3 weeks as 1 course of treatment. The treatment is continued for 2 courses.

Patients in group B: the cake prepared in comparative example 1 was moxibustion applied topically, 3 times a week for 15 minutes, 3 weeks being 1 course of treatment. The treatment is continued for 2 courses.

Wherein the treatment method comprises the following steps:

1) pressing the cake moxibustion round into dough with the diameter of 3cm, placing the dough on the treatment acupuncture point of a patient, igniting a 3cm moxa roll, placing the moxa roll in the middle of the dough and fixing; (avoidance of skin lesions, mucous membranes, allergies, etc.);

2) after 15min, the moxa stick is burnt out, and removed together with the cake, preferably with a local skin areola.

3. Criteria for efficacy assessment

And (3) curing: the symptom signs are completely disappeared, the VAS pain score is 0, the affected part can freely move, and no recurrence is caused;

the effect is shown: the symptom and sign basically disappear, the affected part is obviously improved, and the VAS pain score is 1-2, so that the original work can be basically recovered;

the method has the following advantages: pain was significantly reduced, VAS pain scored 3-4, with slight discomfort from excessive movement;

and (4) invalidation: pain and activity of affected parts did not change significantly before and after treatment, and VAS pain score was greater than 4.

The basic method for VAS pain scoring is to use a moving scale about 10cm long, one side of which is marked with 10 scales, the two ends are respectively a 0-point and a 10-point, the 0-point represents no pain, and the 10-point represents the most severe pain which is difficult to bear. The participators do not need to fill in complicated questionnaires, only need to look at a pain ruler and then speak a number between 0 and 10.

4. Therapeutic effects

Group A: among 151 patients, 83 patients are cured, accounting for 55%; 41 cases of obvious effect account for 27.2 percent; 23 cases of effectiveness account for 15.2 percent; ineffective 4 cases, account for 2.6%. The total effective rate is 97.4%.

Group B: among 151 patients, 85 patients are cured and account for 56.3%; 44 cases of obvious effect account for 29.1 percent; 19 effective cases account for 12.6 percent; ineffective 3 cases, account for 2%. The total effective rate is 98%.

Compared with example 1, the acanthopanax bark, the astragalus membranaceus and the asarum are additionally added in the comparative example 1, wherein the acanthopanax bark, the astragalus membranaceus and the asarum are common traditional Chinese medicines for treating rheumatism, and after the acanthopanax bark, the astragalus membranaceus and the asarum are additionally added in the traditional Chinese medicine composition in the example 1, the two groups of treatment effects have no significant difference, and it can be seen that the traditional Chinese medicine composition in the example 1 is not combined randomly, but has a synergistic effect.

The present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art. Furthermore, the embodiments of the present invention and the features of the embodiments may be combined with each other without conflict.

Claims

1. a medicinal cake moxibustion for the treatment of chronic lumbar muscle strain, wind-cold-damp arthralgia, comprising a Chinese medicinal composition, and the Chinese medicinal composition is made up of the raw material medicines of the following parts by weight: 5～18 parts of hematoxylin, 5～18 parts 10 parts of Angelica, 5-10 parts of safflower, 1-5 parts of white mustard seeds, 5-15 parts of Corydalis, 10-12 parts of cinnamon, 5-10 parts of Sichuan aconite, 12-20 parts of dried ginger , 30 to 70 servings of ginger.

2. The medicinal cake moxibustion according to claim 1, further comprising oil and flour.

3. The medicinal cake moxibustion according to claim 2, wherein the oil is sesame oil, olive oil, sesame oil or cottonseed oil.

4. The preparation method of the medicinal cake moxibustion according to any one of claims 1 to 3, comprising the following steps:

S1: Pulverize hematoxylin, angelica, safflower, white mustard seed, Corydalis, cinnamon, Sichuan aconite, dried ginger and sieve;

S2: add water to ginger to make ginger juice;

S3: Mix the flour with the medicinal materials crushed in step S1, add ginger juice and oil to prepare medicinal cakes.

5. The preparation method according to claim 4, wherein the mesh number of the sieve in step S1 is 150-250 mesh.

6 . The preparation method according to claim 4 , wherein the mass ratio of ginger to water in the step S2 is 1: (8～12). 7 .

7. The application of the medicinal cake moxibustion according to any one of claims 1 to 3 in the preparation of medicines for the treatment of chronic lumbar muscle strain and wind-cold-dampness arthralgia.