CN113209187A - Traditional Chinese medicine prescription for treating bone fracture and bone injury - Google Patents
Traditional Chinese medicine prescription for treating bone fracture and bone injury Download PDFInfo
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- 208000010392 Bone Fractures Diseases 0.000 title claims abstract description 26
- 239000003814 drug Substances 0.000 title claims abstract description 23
- 206010061363 Skeletal injury Diseases 0.000 title claims abstract description 12
- 229940079593 drug Drugs 0.000 claims description 12
- 244000020518 Carthamus tinctorius Species 0.000 claims description 11
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims description 11
- 241000736199 Paeonia Species 0.000 claims description 11
- 244000236658 Paeonia lactiflora Species 0.000 claims description 11
- 235000008598 Paeonia lactiflora Nutrition 0.000 claims description 11
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 11
- 241000405414 Rehmannia Species 0.000 claims description 11
- 235000001287 Guettarda speciosa Nutrition 0.000 claims description 7
- 244000299790 Rheum rhabarbarum Species 0.000 claims description 6
- 235000009411 Rheum rhabarbarum Nutrition 0.000 claims description 6
- 239000002994 raw material Substances 0.000 claims description 6
- 244000144730 Amygdalus persica Species 0.000 claims description 5
- 235000006040 Prunus persica var persica Nutrition 0.000 claims description 5
- 230000006378 damage Effects 0.000 claims description 5
- 241000628997 Flos Species 0.000 claims description 2
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 2
- 210000000582 semen Anatomy 0.000 claims description 2
- 244000061520 Angelica archangelica Species 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 241000213006 Angelica dahurica Species 0.000 claims 1
- 239000008280 blood Substances 0.000 abstract description 16
- 210000004369 blood Anatomy 0.000 abstract description 16
- 230000000694 effects Effects 0.000 abstract description 14
- 230000036407 pain Effects 0.000 abstract description 14
- 210000000988 bone and bone Anatomy 0.000 abstract description 11
- 230000017531 blood circulation Effects 0.000 abstract description 8
- 210000002435 tendon Anatomy 0.000 abstract description 7
- 230000001737 promoting effect Effects 0.000 abstract description 6
- 230000001105 regulatory effect Effects 0.000 abstract description 4
- 230000007246 mechanism Effects 0.000 abstract description 2
- 231100000957 no side effect Toxicity 0.000 abstract description 2
- 230000008506 pathogenesis Effects 0.000 abstract description 2
- 206010017076 Fracture Diseases 0.000 description 14
- 230000008961 swelling Effects 0.000 description 7
- 241000125175 Angelica Species 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 208000014674 injury Diseases 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 241000382455 Angelica sinensis Species 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 208000012661 Dyskinesia Diseases 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 208000021945 Tendon injury Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 210000003414 extremity Anatomy 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 230000005906 menstruation Effects 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000002040 relaxant effect Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 230000008733 trauma Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 244000183685 Citrus aurantium Species 0.000 description 1
- 235000007716 Citrus aurantium Nutrition 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 208000034656 Contusions Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 206010014080 Ecchymosis Diseases 0.000 description 1
- 208000032912 Local swelling Diseases 0.000 description 1
- 208000016285 Movement disease Diseases 0.000 description 1
- 230000035508 accumulation Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 208000034526 bruise Diseases 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
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- 229910052742 iron Inorganic materials 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 238000009527 percussion Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 210000001364 upper extremity Anatomy 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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Abstract
The invention discloses a traditional Chinese medicine prescription for treating bone fracture and bone injury, which comprises prescription 1 and prescription 2, and the traditional Chinese medicine prescription divides the bone fracture treatment into two stages according to the pathogenesis of the bone fracture and the traditional Chinese medicine treatment mechanism, wherein the first stage adopts prescription 1 mainly for promoting blood circulation and removing blood stasis, relieving pain and regulating qi, and the second stage adopts prescription 2 for promoting blood circulation and connecting tendons and bones, so that the traditional Chinese medicine prescription can effectively treat the bone fracture, has obvious treatment effect, short treatment course and no side effect.
Description
Technical Field
The invention relates to the technical field of medicines, in particular to a traditional Chinese medicine prescription for treating bone fracture and bone injury.
Background
Bone injuries are commonly referred to as bone fractures, which refers to a disease in which bone mass is partially or completely broken due to trauma or pathology. Fracture can be usually divided into block, broken or oblique fracture, and the affected part may have various manifestations such as blood stasis, swelling and pain, dislocation, deformity, bone sound, pain due to axial percussion, abnormal movement and dysfunction. The main clinical manifestations are localized pain and tenderness in fracture, local swelling and ecchymosis, complete loss of limb functional parts, complete bone and deformity and abnormal movement of limbs. The common treatment methods for fracture include manual reduction, incision reduction, clamping, fixation, etc. However, these methods are long and the therapeutic effect is not very significant.
Disclosure of Invention
Therefore, based on the background, the invention provides a Chinese medicinal formula for treating bone fracture and bone injury with remarkable curative effect and short treatment course.
The invention is realized by the following technical scheme:
a Chinese medicinal composition for treating fracture and bone injury comprises formula 1 and formula 2,
the prescription 1 consists of the following raw material medicines: radix Angelicae sinensis, fructus Aurantii (parched), radix rehmanniae Preparata, radix Paeoniae alba (parched), Carthami flos, semen Persicae, and radix Paeoniae Rubra;
the prescription 2 consists of the following raw material medicines: chinese angelica root, white peony root (fried), prepared rhizome of rehmannia, safflower, red peony root, rhubarb (wine).
Further, the bulk drugs of the formula 1 are respectively: 30 parts of angelica, 30 parts of fructus aurantii (fried), 20 parts of prepared rehmannia root, 20 parts of white peony root (fried), 10 parts of safflower, 10 parts of peach kernel and 10 parts of red peony root; the bulk drugs of the prescription 2 are respectively as follows: 15 parts of angelica, 20 parts of white peony root (fried), 30 parts of prepared rehmannia root, 20 parts of safflower, 10 parts of red peony root and 15 parts of rhubarb (wine).
Further, formulations 1 and 2 are oral formulations.
In the formula, the angelica is warm in nature, sweet and pungent in taste, and has the effects of enriching and activating blood, regulating menstruation and relieving pain, relaxing bowel and the like; peach kernel, neutral in nature, bitter and sweet in taste, has the effects of promoting blood circulation, removing blood stasis, loosening the bowel to relieve constipation and the like; safflower is warm in nature and pungent in taste, and has the effects of promoting blood circulation, dredging meridian, removing blood stasis, relieving pain and the like; the prepared rhizome of rehmannia is warm in nature and sweet in taste, and has the effects of tonifying kidney, nourishing yin, nourishing blood, tonifying deficiency and the like; the bitter orange is slightly cold in nature, bitter, pungent and sour in taste, and has the effects of regulating qi, relieving epigastric distention, activating stagnancy, relieving distension and the like; white peony root, slightly cold in nature, bitter and sour in taste, has the effects of nourishing blood, regulating menstruation, astringing yin, arresting sweating, softening liver, relieving pain, calming liver yang and the like; red peony root, slightly cold in nature and bitter in taste, has the effects of clearing heat and cooling blood, dissipating blood stasis and relieving pain and the like.
Fracture injury is usually accompanied by skin, flesh, pulse and tendon injuries, and the influence on tendons is particularly important. Tendon and bone injuries are likely to be injured after fracture, and the change of liver, kidney and qi and blood is affected by the injury of bones and muscles. Fracture, channel damage, qi and blood separation, blood stasis accumulation, swelling and pain due to trauma, and failure of muscles and bones to nourish. The traditional Chinese medicine has a saying that bones cannot be connected when blood does not activate, and bones cannot be connected when blood stasis does not remove, so that the treatment mainly aims at relaxing tendons and collaterals, relieving swelling and pain, promoting blood circulation and removing blood stasis in the early period of the tendon and bone connection treatment, and mainly aims at promoting blood circulation and connecting tendons and bones in the later period.
According to the invention, according to the pathogenesis of the fracture and the traditional Chinese medicine treatment mechanism thereof, the fracture treatment is divided into two stages, the first stage adopts the prescription 1 to mainly promote blood circulation to remove blood stasis, relieve pain and regulate qi, and the second stage adopts the prescription 2 to promote blood circulation and join tendons and bones, and the medicines are used together, so that the fracture can be effectively treated, the treatment effect is remarkable, the treatment course is short, and no side effect is caused.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1: a Chinese medicinal composition for treating fracture and bone injury comprises formula 1 and formula 2,
the raw material medicines of the prescription 1 are respectively as follows by weight: 30 parts of angelica, 30 parts of fructus aurantii (fried), 20 parts of prepared rehmannia root, 20 parts of white peony root (fried), 10 parts of safflower, 10 parts of peach kernel and 10 parts of red peony root; the bulk drugs of the prescription 2 are respectively as follows: 15 parts of angelica, 20 parts of white peony root (fried), 30 parts of prepared rehmannia root, 20 parts of safflower, 10 parts of red peony root and 15 parts of rhubarb (wine).
In the prescription 1 of the embodiment, 30 g of angelica sinensis, 30 g of fructus aurantii (fried), 20 g of prepared rehmannia root, 20 g of white peony root (fried), 10 g of safflower, 10 g of peach kernel and 10 g of red peony root, and in the prescription 2, 15 g of angelica sinensis, 20 g of white peony root (fried), 30 g of prepared rehmannia root, 20 g of safflower, 10 g of red peony root and 15 g of rhubarb (wine) are adopted.
When the prescription of the invention is used for treating fracture, the prescription 1 can be decocted in water firstly, and then the prescription 2 can be decocted in water for taking.
Example 2: therapeutic effect
The treatment time is 300, wherein 167 men and 133 women have the same treatment time, wherein 98 upper limbs are fractured, 111 lower limbs are fractured, 91 trunk are fractured, and the patients are injured to the longest treatment time of 14d and the shortest treatment time of 2 h.
The treatment process comprises the following steps: after the patient takes the prescription 1 of the embodiment for 3 days, the patient is changed to take the prescription 2 and continues to take the treatment for 12 days, and the external fixation is added in the treatment process.
And (3) diagnosis results:
diagnostic evaluation criteria:
the effect is shown: the clinical symptoms and physical symptoms basically disappear, no obvious tenderness exists on the part, and the weight bearing can be carried out for functional exercise;
the method has the following advantages: the clinical symptoms and physical signs are obviously improved, and the local pain and swelling are obviously relieved.
And (4) invalidation: no obvious improvement on clinical symptoms and physical signs, no obvious reduction on local pain and swelling, and movement disorder.
105 cases of obvious effect, 187 cases of effect and 8 cases of no effect, and the effective rate is 97.3 percent.
Implementation 3: typical case
Case 1: wangzhi, male, 43 years old, because of the bruise and redness and swelling of the skin under the rib, the patient is hard to feel painful when coughing after being collided by the electric vehicle when walking, and the rib is unhappy after going to a hospital and taking a picture, after taking the prescription 1 of the embodiment 1 for one day, and after changing the prescription 2 for two days, the patient can be cured.
Case 2: in 34 years old, the arms of a male in Maji cannot be lifted up by striking the middle part with an iron rod, and pain and swelling are obvious and cannot move. Taking X-ray, examining the correct position to determine the transverse fracture of the hit part, and fixing with a splint pad for surgery. After taking the prescription 1 of example 1 for three days, and after taking the prescription 2 for seven days, the patient can be cured.
The present invention and the embodiments thereof have been described above, and the description is not limiting, and the embodiments shown in the examples are only one of the embodiments of the present invention, and the practical implementation manner is not limited thereto. In summary, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the spirit and scope of the invention as defined by the appended claims.
Claims (3)
1. A Chinese medicinal preparation for treating bone fracture and bone injury is characterized in that,
which comprises a prescription 1 and a prescription 2,
the prescription 1 consists of the following raw material medicines: radix Angelicae sinensis, fructus Aurantii (parched), radix rehmanniae Preparata, radix Paeoniae alba (parched), Carthami flos, semen Persicae, and radix Paeoniae Rubra;
the prescription 2 consists of the following raw material medicines: chinese angelica root, white peony root (fried), prepared rhizome of rehmannia, safflower, red peony root, rhubarb (wine).
2. The traditional Chinese medicine prescription for treating bone fracture and injury according to claim 1, wherein the raw material medicines of prescription 1 are respectively: 30 parts of angelica, 30 parts of fructus aurantii (fried), 20 parts of prepared rehmannia root, 20 parts of white peony root (fried), 10 parts of safflower, 10 parts of peach kernel and 10 parts of red peony root; the bulk drugs of the prescription 2 are respectively as follows: 15 parts of angelica, 20 parts of white peony root (fried), 30 parts of prepared rehmannia root, 20 parts of safflower, 10 parts of red peony root and 15 parts of rhubarb (wine).
3. The traditional Chinese medicine prescription for treating bone fracture and injury according to claim 1, wherein prescription 1 and prescription 2 are oral preparations.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN202110570424.1A CN113209187A (en) | 2021-05-25 | 2021-05-25 | Traditional Chinese medicine prescription for treating bone fracture and bone injury |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202110570424.1A CN113209187A (en) | 2021-05-25 | 2021-05-25 | Traditional Chinese medicine prescription for treating bone fracture and bone injury |
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| CN113209187A true CN113209187A (en) | 2021-08-06 |
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| CN202110570424.1A Withdrawn CN113209187A (en) | 2021-05-25 | 2021-05-25 | Traditional Chinese medicine prescription for treating bone fracture and bone injury |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1876041A (en) * | 2006-04-21 | 2006-12-13 | 刘皇琼 | A compound Chinese medicine for treating bone fracture quickly |
| CN102188535A (en) * | 2010-03-10 | 2011-09-21 | 胡清文 | Chinese medicine preparation for nourishing blood and promoting blood circulation and preparation method thereof |
| CN105535237A (en) * | 2015-12-29 | 2016-05-04 | 广东一方制药有限公司 | Preparation method and quality control method for peach-kernel-safflower decoction-of-four-ingredients formula granules |
-
2021
- 2021-05-25 CN CN202110570424.1A patent/CN113209187A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1876041A (en) * | 2006-04-21 | 2006-12-13 | 刘皇琼 | A compound Chinese medicine for treating bone fracture quickly |
| CN102188535A (en) * | 2010-03-10 | 2011-09-21 | 胡清文 | Chinese medicine preparation for nourishing blood and promoting blood circulation and preparation method thereof |
| CN105535237A (en) * | 2015-12-29 | 2016-05-04 | 广东一方制药有限公司 | Preparation method and quality control method for peach-kernel-safflower decoction-of-four-ingredients formula granules |
Non-Patent Citations (6)
| Title |
|---|
| 岳端利: "《临床骨伤科学》", 30 June 2018, 西安交通大学出版社 * |
| 张宝林 等: "《中医儿科集成》", 31 May 1991, 湖南大学技术出版社 * |
| 曹是褒 等: "《方剂歌诀394首》", 31 January 2018, 广东科技出版社 * |
| 杨旸: "《实用中医诊疗手册》", 31 March 2017, 河南科学技术出版社 * |
| 范颖 等: "《中药药对配方理论及应用》", 31 October 2015, 辽宁科学技术出版社 * |
| 鞠可心: "中药配合DHS内固定治疗老年股骨粗隆间骨折的疗效分析", 《辽宁中医药大学学报》 * |
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Application publication date: 20210806 |